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Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Phospholipase C-beta-1'   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phospholipase C-beta-1


(Homo sapiens)
BDBM50030627
PNG
((+-)-MCPG | (R,S)-alpha-Methyl-4-carboxyphenylglyc...)
Show SMILES CC(N)(C(O)=O)c1ccc(cc1)C(O)=O
Show InChI InChI=1S/C10H11NO4/c1-10(11,9(14)15)7-4-2-6(3-5-7)8(12)13/h2-5H,11H2,1H3,(H,12,13)(H,14,15)
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PC sid
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Article
PubMed
n/an/a 1.50E+5n/an/an/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Antagonistic activity against phospholipase C (PLC) was determined in adult rat hippocampal slices


Citation and Details
More data for this
Ligand-Target Pair
Phospholipase C-beta-1


(Homo sapiens)
BDBM66976
PNG
((1S,3R)-1-aminocyclopentane-1,3-dicarboxylic acid;...)
Show SMILES N[C@]1(CC[C@H](C1)C(O)=O)C(O)=O
Show InChI InChI=1S/C7H11NO4/c8-7(6(11)12)2-1-4(3-7)5(9)10/h4H,1-3,8H2,(H,9,10)(H,11,12)/t4-,7+/m1/s1
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CHEMBL
PC cid
PC sid
PDB
UniChem

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AffyNet 
Article
PubMed
n/an/an/an/a 5.00E+4n/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Agonistic activity against phospholipase C (PLC) was determined in adult rat hippocampal slices


Citation and Details
More data for this
Ligand-Target Pair
Phospholipase C-beta-1


(Homo sapiens)
BDBM50050924
PNG
((1R,2S,3S)-2-(Amino-carboxy-methyl)-3-phenyl-cyclo...)
Show SMILES NC([C@@H]1[C@@H]([C@H]1c1ccccc1)C(O)=O)C(O)=O
Show InChI InChI=1S/C12H13NO4/c13-10(12(16)17)8-7(9(8)11(14)15)6-4-2-1-3-5-6/h1-5,7-10H,13H2,(H,14,15)(H,16,17)/t7-,8-,9+,10?/m0/s1
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CHEMBL
PC cid
PC sid
UniChem

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Article
PubMed
n/an/an/an/a>3.00E+5n/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Agonistic activity against phospholipase C (PLC) was determined in adult rat hippocampal slices


Citation and Details
More data for this
Ligand-Target Pair
Phospholipase C-beta-1


(Homo sapiens)
BDBM50079183
PNG
((2S)-amino(3,5-dihydroxyphenyl)ethanoic acid | (S)...)
Show SMILES N[C@H](C(O)=O)c1cc(O)cc(O)c1
Show InChI InChI=1S/C8H9NO4/c9-7(8(12)13)4-1-5(10)3-6(11)2-4/h1-3,7,10-11H,9H2,(H,12,13)/t7-/m0/s1
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CHEMBL
DrugBank
KEGG
PC cid
PC sid
PDB
UniChem

Similars

AffyNet 
Article
PubMed
n/an/an/an/a 6.50E+4n/an/an/an/a



Università di Perugia

Curated by ChEMBL


Assay Description
Agonistic activity against phospholipase C (PLC) was determined in adult rat hippocampal slices


Citation and Details
More data for this
Ligand-Target Pair