Target (Institution) | Ligand | Target Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
mTOR/ Hck (Homo sapiens (human)) | BDBM36409![]() (2-(4-amino-1-isopropyl-1H-pyrazolo[3,4-d]pyrimidin...) | PDB KEGG UniProtKB/SwissProt antibodypedia antibodypedia antibodypedia GoogleScholar AffyNet ![]() | Purchase MMDB PC cid PC sid PDB UniChem Patents Similars AffyNet ![]() | PDB Article PubMed | n/a | n/a | 1.20E+3 | n/a | n/a | n/a | n/a | n/a | n/a |
University of California, San Francisco | Assay Description The assays were performed in 96-well microtiter plates that had been coated with a polyGluTyr peptide. Negative control wells received buffer alone w... | Nat Chem Biol 4: 691-9 (2008) | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |