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Compile Data Set for Download or QSAR

Found 4 hits Enz. Inhib. hit(s) with Target = 'Inosine-uridine preferring nucleoside hydrolase'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Inosine-uridine preferring nucleoside hydrolase


(Crithidia fasciculata)
BDBM50187701
PNG
(CHEMBL3827395)
Show SMILES Nc1ncnc2C(C=Nc12)[C@@H]1N[C@H](CO)[C@@H](O)[C@H]1O
Show InChI InChI=1S/C11H15N5O3/c12-11-8-6(14-3-15-11)4(1-13-8)7-10(19)9(18)5(2-17)16-7/h1,3-5,7,9-10,16-19H,2H2,(H2,12,14,15)/t4?,5-,7+,9-,10+/m1/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
7n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Inhibition of Crithidia fasciculata inosine-uridine nucleoside hydrolase expressed in Escherichia coli using p-nitrophenyl beta-D-ribofuranoside as s...


Eur J Med Chem 118: 121-42 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.034
BindingDB Entry DOI: 10.7270/Q2ZP482X
More data for this
Ligand-Target Pair
Inosine-uridine preferring nucleoside hydrolase


(Crithidia fasciculata)
BDBM50187700
PNG
(CHEMBL3828042)
Show SMILES Nc1nc(O)c2ncn(C[C@@H]3N[C@H](CO)[C@@H](O)[C@H]3O)c2n1
Show InChI InChI=1S/C11H16N6O4/c12-11-15-9-6(10(21)16-11)13-3-17(9)1-4-7(19)8(20)5(2-18)14-4/h3-5,7-8,14,18-20H,1-2H2,(H3,12,15,16,21)/t4-,5+,7-,8+/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.40E+3n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Inhibition of Crithidia fasciculata inosine-uridine nucleoside hydrolase expressed in Escherichia coli using p-nitrophenyl beta-D-ribofuranoside as s...


Eur J Med Chem 118: 121-42 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.034
BindingDB Entry DOI: 10.7270/Q2ZP482X
More data for this
Ligand-Target Pair
Inosine-uridine preferring nucleoside hydrolase


(Crithidia fasciculata)
BDBM50187702
PNG
(CHEMBL3828258)
Show SMILES Nc1ncnc2n(C[C@@H]3N[C@H](CO)[C@@H](O)[C@H]3O)cnc12
Show InChI InChI=1S/C11H16N6O3/c12-10-7-11(14-3-13-10)17(4-15-7)1-5-8(19)9(20)6(2-18)16-5/h3-6,8-9,16,18-20H,1-2H2,(H2,12,13,14)/t5-,6+,8-,9+/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.40E+3n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Inhibition of Crithidia fasciculata inosine-uridine nucleoside hydrolase expressed in Escherichia coli using p-nitrophenyl beta-D-ribofuranoside as s...


Eur J Med Chem 118: 121-42 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.034
BindingDB Entry DOI: 10.7270/Q2ZP482X
More data for this
Ligand-Target Pair
Inosine-uridine preferring nucleoside hydrolase


(Crithidia fasciculata)
BDBM50187703
PNG
(CHEMBL3827853)
Show SMILES OC[C@H]1N[C@@H](Cn2cnc3c(O)ncnc23)[C@H](O)[C@@H]1O
Show InChI InChI=1S/C11H15N5O4/c17-2-6-9(19)8(18)5(15-6)1-16-4-14-7-10(16)12-3-13-11(7)20/h3-6,8-9,15,17-19H,1-2H2,(H,12,13,20)/t5-,6+,8-,9+/m0/s1
PDB

UniProtKB/TrEMBL

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
5.40E+3n/an/an/an/an/an/an/an/a



Medical University of Lodz

Curated by ChEMBL


Assay Description
Inhibition of Crithidia fasciculata inosine-uridine nucleoside hydrolase expressed in Escherichia coli using p-nitrophenyl beta-D-ribofuranoside as s...


Eur J Med Chem 118: 121-42 (2016)


Article DOI: 10.1016/j.ejmech.2016.04.034
BindingDB Entry DOI: 10.7270/Q2ZP482X
More data for this
Ligand-Target Pair