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Compile Data Set for Download or QSAR

Found 729 hits Enz. Inhib. hit(s) with Target = 'Lysophosphatidic acid receptor 1'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50176394
PNG
(CHEMBL202361 | octanoic acid (R)-2-octanoyloxy-3-t...)
Show SMILES CCCCCCCC(=O)OC[C@H](COP(O)(O)=S)OC(=O)CCCCCCC
Show InChI InChI=1S/C19H37O7PS/c1-3-5-7-9-11-13-18(20)24-15-17(16-25-27(22,23)28)26-19(21)14-12-10-8-6-4-2/h17H,3-16H2,1-2H3,(H2,22,23,28)/t17-/m1/s1
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5n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Activity at LPA3 receptor transfected RH7777 cells


Bioorg Med Chem Lett 16: 633-40 (2005)


Article DOI: 10.1016/j.bmcl.2005.10.031
BindingDB Entry DOI: 10.7270/Q2ZC82DB
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50170847
PNG
(CHEMBL190484 | Thiophosphoric acid (E)-dodec-9-eny...)
Show SMILES CC\C=C\CCCCCCCCOP(O)(O)=S
Show InChI InChI=1S/C12H25O3PS/c1-2-3-4-5-6-7-8-9-10-11-12-15-16(13,14)17/h3-4H,2,5-12H2,1H3,(H2,13,14,17)/b4-3+
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14n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cells


J Med Chem 48: 4919-30 (2005)


Article DOI: 10.1021/jm049609r
BindingDB Entry DOI: 10.7270/Q2HD7V5N
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50170860
PNG
(CHEMBL191365 | Thiophosphoric acid dodecyl ester)
Show SMILES CCCCCCCCCCCCOP(O)(O)=S
Show InChI InChI=1S/C12H27O3PS/c1-2-3-4-5-6-7-8-9-10-11-12-15-16(13,14)17/h2-12H2,1H3,(H2,13,14,17)
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14n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cells


J Med Chem 48: 4919-30 (2005)


Article DOI: 10.1021/jm049609r
BindingDB Entry DOI: 10.7270/Q2HD7V5N
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50170852
PNG
(CHEMBL187402 | Thiophosphoric acid (E)-tetradec-9-...)
Show SMILES CCCC\C=C\CCCCCCCCOP(O)(O)=S
Show InChI InChI=1S/C14H29O3PS/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17-18(15,16)19/h5-6H,2-4,7-14H2,1H3,(H2,15,16,19)/b6-5+
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14n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cells


J Med Chem 48: 4919-30 (2005)


Article DOI: 10.1021/jm049609r
BindingDB Entry DOI: 10.7270/Q2HD7V5N
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1


(Homo sapiens (Human))
BDBM50146232
PNG
(CHEMBL440696 | Phosphoric acid mono-{(R)-2-((Z)-oc...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](COP(O)(O)=O)Cc1ccc(OCc2ccccn2)cc1
Show InChI InChI=1S/C33H51N2O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-33(36)35-31(28-41-42(37,38)39)26-29-21-23-32(24-22-29)40-27-30-19-17-18-25-34-30/h9-10,17-19,21-25,31H,2-8,11-16,20,26-28H2,1H3,(H,35,36)(H2,37,38,39)/b10-9-/t31-/m1/s1
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18n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro ability to antagonize LPA-evoked [35S]-GTP-gammaS binding to lysophosphatidic acid receptor 1 in HEK293T cell lines


Bioorg Med Chem Lett 14: 2735-40 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.076
BindingDB Entry DOI: 10.7270/Q2DF6QN9
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1


(Homo sapiens (Human))
BDBM50146232
PNG
(CHEMBL440696 | Phosphoric acid mono-{(R)-2-((Z)-oc...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](COP(O)(O)=O)Cc1ccc(OCc2ccccn2)cc1
Show InChI InChI=1S/C33H51N2O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-33(36)35-31(28-41-42(37,38)39)26-29-21-23-32(24-22-29)40-27-30-19-17-18-25-34-30/h9-10,17-19,21-25,31H,2-8,11-16,20,26-28H2,1H3,(H,35,36)(H2,37,38,39)/b10-9-/t31-/m1/s1
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18n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Binding affinity towards Lysophosphatidic acid 1 (LPA1) receptor


Bioorg Med Chem Lett 14: 4069-74 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.023
BindingDB Entry DOI: 10.7270/Q2930SM1
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1


(Homo sapiens (Human))
BDBM50150007
PNG
(CHEMBL183221 | Phosphoric acid mono-((R)-2-((Z)-oc...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](COP(O)(O)=O)Cc1ccc(OCc2cc(OCC(F)(F)F)ccn2)cc1
Show InChI InChI=1S/C35H52F3N2O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-34(41)40-31(27-47-48(42,43)44)24-29-18-20-32(21-19-29)45-26-30-25-33(22-23-39-30)46-28-35(36,37)38/h9-10,18-23,25,31H,2-8,11-17,24,26-28H2,1H3,(H,40,41)(H2,42,43,44)/b10-9-/t31-/m1/s1
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19n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Binding affinity towards Lysophosphatidic acid 1 (LPA1) receptor


Bioorg Med Chem Lett 14: 4069-74 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.023
BindingDB Entry DOI: 10.7270/Q2930SM1
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1


(Homo sapiens (Human))
BDBM50149996
PNG
(CHEMBL183143 | Phosphoric acid mono-[3-[4-(4-ethox...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](COP(O)(O)=O)Cc1ccc(OCc2cc(OCC)ccn2)cc1
Show InChI InChI=1S/C35H55N2O7P/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-35(38)37-32(29-44-45(39,40)41)26-30-20-22-33(23-21-30)43-28-31-27-34(42-4-2)24-25-36-31/h11-12,20-25,27,32H,3-10,13-19,26,28-29H2,1-2H3,(H,37,38)(H2,39,40,41)/b12-11-/t32-/m1/s1
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26n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Binding affinity towards Lysophosphatidic acid 1 (LPA1) receptor


Bioorg Med Chem Lett 14: 4069-74 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.023
BindingDB Entry DOI: 10.7270/Q2930SM1
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50170858
PNG
(CHEMBL190349 | Phosphoric acid mono-((E)-dodec-9-e...)
Show SMILES CC\C=C\CCCCCCCCOP(O)(O)=O
Show InChI InChI=1S/C12H25O4P/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15/h3-4H,2,5-12H2,1H3,(H2,13,14,15)/b4-3+
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27n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cells


J Med Chem 48: 4919-30 (2005)


Article DOI: 10.1021/jm049609r
BindingDB Entry DOI: 10.7270/Q2HD7V5N
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1


(Homo sapiens (Human))
BDBM50149997
PNG
(CHEMBL362053 | Phosphoric acid mono-[3-[4-(4-metho...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](COP(O)(O)=O)Cc1ccc(OCc2ncc(C)c(OC)c2C)cc1
Show InChI InChI=1S/C36H57N2O7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-35(39)38-32(27-45-46(40,41)42)25-31-21-23-33(24-22-31)44-28-34-30(3)36(43-4)29(2)26-37-34/h12-13,21-24,26,32H,5-11,14-20,25,27-28H2,1-4H3,(H,38,39)(H2,40,41,42)/b13-12-/t32-/m1/s1
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28n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Binding affinity towards Lysophosphatidic acid 1 (LPA1) receptor


Bioorg Med Chem Lett 14: 4069-74 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.023
BindingDB Entry DOI: 10.7270/Q2930SM1
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1


(Homo sapiens (Human))
BDBM50146240
PNG
(CHEMBL91058 | Phosphoric acid mono-[(R)-3-[4-(3-me...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](COP(O)(O)=O)Cc1ccc(OCc2cccc(OC)c2)cc1
Show InChI InChI=1S/C35H54NO7P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21-35(37)36-32(29-43-44(38,39)40)26-30-22-24-33(25-23-30)42-28-31-19-18-20-34(27-31)41-2/h10-11,18-20,22-25,27,32H,3-9,12-17,21,26,28-29H2,1-2H3,(H,36,37)(H2,38,39,40)/b11-10-/t32-/m1/s1
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34n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro ability to antagonize LPA-evoked [35S]-GTP-gammaS binding to lysophosphatidic acid receptor 1 in HEK293T cell lines


Bioorg Med Chem Lett 14: 2735-40 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.076
BindingDB Entry DOI: 10.7270/Q2DF6QN9
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1


(Homo sapiens (Human))
BDBM50150000
PNG
(CHEMBL182446 | Phosphoric acid mono-[(R)-3-{4-[4-(...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](COP(O)(O)=O)Cc1ccc(OCc2cc(OCCOC)ccn2)cc1
Show InChI InChI=1S/C36H57N2O8P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-36(39)38-33(30-46-47(40,41)42)27-31-19-21-34(22-20-31)45-29-32-28-35(23-24-37-32)44-26-25-43-2/h10-11,19-24,28,33H,3-9,12-18,25-27,29-30H2,1-2H3,(H,38,39)(H2,40,41,42)/b11-10-/t33-/m1/s1
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35n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Binding affinity towards Lysophosphatidic acid 1 (LPA1) receptor


Bioorg Med Chem Lett 14: 4069-74 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.023
BindingDB Entry DOI: 10.7270/Q2930SM1
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50149996
PNG
(CHEMBL183143 | Phosphoric acid mono-[3-[4-(4-ethox...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](COP(O)(O)=O)Cc1ccc(OCc2cc(OCC)ccn2)cc1
Show InChI InChI=1S/C35H55N2O7P/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-35(38)37-32(29-44-45(39,40)41)26-30-20-22-33(23-21-30)43-28-31-27-34(42-4-2)24-25-36-31/h11-12,20-25,27,32H,3-10,13-19,26,28-29H2,1-2H3,(H,37,38)(H2,39,40,41)/b12-11-/t32-/m1/s1
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39n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Binding affinity towards Lysophosphatidic acid 3 (LPA3) receptor


Bioorg Med Chem Lett 14: 4069-74 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.023
BindingDB Entry DOI: 10.7270/Q2930SM1
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50149997
PNG
(CHEMBL362053 | Phosphoric acid mono-[3-[4-(4-metho...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](COP(O)(O)=O)Cc1ccc(OCc2ncc(C)c(OC)c2C)cc1
Show InChI InChI=1S/C36H57N2O7P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-35(39)38-32(27-45-46(40,41)42)25-31-21-23-33(24-22-31)44-28-34-30(3)36(43-4)29(2)26-37-34/h12-13,21-24,26,32H,5-11,14-20,25,27-28H2,1-4H3,(H,38,39)(H2,40,41,42)/b13-12-/t32-/m1/s1
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39n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Binding affinity towards Lysophosphatidic acid 3 (LPA3) receptor


Bioorg Med Chem Lett 14: 4069-74 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.023
BindingDB Entry DOI: 10.7270/Q2930SM1
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50176391
PNG
(CHEMBL202185 | octanoic acid (R)-2-octanoyloxy-3-p...)
Show SMILES CCCCCCCC(=O)OC[C@H](COP(O)(O)=O)OC(=O)CCCCCCC
Show InChI InChI=1S/C19H37O8P/c1-3-5-7-9-11-13-18(20)25-15-17(16-26-28(22,23)24)27-19(21)14-12-10-8-6-4-2/h17H,3-16H2,1-2H3,(H2,22,23,24)/t17-/m1/s1
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39n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Activity at LPA3 receptor transfected RH7777 cells


Bioorg Med Chem Lett 16: 633-40 (2005)


Article DOI: 10.1016/j.bmcl.2005.10.031
BindingDB Entry DOI: 10.7270/Q2ZC82DB
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50170851
PNG
(CHEMBL188591 | Phosphoric acid mono-((E)-tetradec-...)
Show SMILES CC\C=C\CCCCCCCCCCOP(O)(O)=O
Show InChI InChI=1S/C14H29O4P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-18-19(15,16)17/h3-4H,2,5-14H2,1H3,(H2,15,16,17)/b4-3+
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40n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cells


J Med Chem 48: 4919-30 (2005)


Article DOI: 10.1021/jm049609r
BindingDB Entry DOI: 10.7270/Q2HD7V5N
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50150007
PNG
(CHEMBL183221 | Phosphoric acid mono-((R)-2-((Z)-oc...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](COP(O)(O)=O)Cc1ccc(OCc2cc(OCC(F)(F)F)ccn2)cc1
Show InChI InChI=1S/C35H52F3N2O7P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-34(41)40-31(27-47-48(42,43)44)24-29-18-20-32(21-19-29)45-26-30-25-33(22-23-39-30)46-28-35(36,37)38/h9-10,18-23,25,31H,2-8,11-17,24,26-28H2,1H3,(H,40,41)(H2,42,43,44)/b10-9-/t31-/m1/s1
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48n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Binding affinity towards Lysophosphatidic acid 3 (LPA3) receptor


Bioorg Med Chem Lett 14: 4069-74 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.023
BindingDB Entry DOI: 10.7270/Q2930SM1
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1


(Homo sapiens (Human))
BDBM50304580
PNG
(2-(3-(4-nitrophenoxy)phenyl)-1,3-dioxoisoindoline-...)
Show SMILES OC(=O)c1ccc2C(=O)N(C(=O)c2c1)c1cccc(Oc2ccc(cc2)[N+]([O-])=O)c1
Show InChI InChI=1S/C21H12N2O7/c24-19-17-9-4-12(21(26)27)10-18(17)20(25)22(19)14-2-1-3-16(11-14)30-15-7-5-13(6-8-15)23(28)29/h1-11H,(H,26,27)
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48n/an/an/an/an/an/an/an/a



The University of Memphis

Curated by ChEMBL


Assay Description
Binding affinity to LPA1


Bioorg Med Chem 17: 7457-64 (2009)


Article DOI: 10.1016/j.bmc.2009.09.022
BindingDB Entry DOI: 10.7270/Q2GB244M
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50170857
PNG
(CHEMBL187795 | Thiophosphoric acid decyl ester)
Show SMILES CCCCCCCCCCOP(O)(O)=S
Show InChI InChI=1S/C10H23O3PS/c1-2-3-4-5-6-7-8-9-10-13-14(11,12)15/h2-10H2,1H3,(H2,11,12,15)
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49n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cells


J Med Chem 48: 4919-30 (2005)


Article DOI: 10.1021/jm049609r
BindingDB Entry DOI: 10.7270/Q2HD7V5N
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50176397
PNG
(CHEMBL203986 | nonanoic acid (S)-2-nonanoyloxy-3-p...)
Show SMILES CCCCCCCCOC[C@@H](COP(O)(O)=O)OCCCCCCCC
Show InChI InChI=1S/C19H41O6P/c1-3-5-7-9-11-13-15-23-17-19(18-25-26(20,21)22)24-16-14-12-10-8-6-4-2/h19H,3-18H2,1-2H3,(H2,20,21,22)/t19-/m0/s1
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50n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Activity at LPA3 receptor transfected RH7777 cells


Bioorg Med Chem Lett 16: 633-40 (2005)


Article DOI: 10.1016/j.bmcl.2005.10.031
BindingDB Entry DOI: 10.7270/Q2ZC82DB
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1


(Homo sapiens (Human))
BDBM50271763
PNG
(3-[3-(3-Carboxy-acryloylamino)-phenylcarbamoyl]-ac...)
Show SMILES OC(=O)\C=C\C(=O)Nc1cccc(NC(=O)\C=C\C(O)=O)c1
Show InChI InChI=1S/C14H12N2O6/c17-11(4-6-13(19)20)15-9-2-1-3-10(8-9)16-12(18)5-7-14(21)22/h1-8H,(H,15,17)(H,16,18)(H,19,20)(H,21,22)/b6-4+,7-5+
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50n/an/an/an/an/an/an/an/a



The University of Memphis

Curated by ChEMBL


Assay Description
Antagonist activity at LPA1 receptor (unknown origin) expressed in rat RH7777 cells assessed as inhibition of LPA-induced intracellular calcium conce...


Bioorg Med Chem 16: 6207-17 (2008)


Article DOI: 10.1016/j.bmc.2008.04.035
BindingDB Entry DOI: 10.7270/Q270817C
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50170843
PNG
(CHEMBL190430 | Phosphoric acid mono-((E)-tetradec-...)
Show SMILES CCCC\C=C\CCCCCCCCOP(O)(O)=O
Show InChI InChI=1S/C14H29O4P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-18-19(15,16)17/h5-6H,2-4,7-14H2,1H3,(H2,15,16,17)/b6-5+
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58n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cells


J Med Chem 48: 4919-30 (2005)


Article DOI: 10.1021/jm049609r
BindingDB Entry DOI: 10.7270/Q2HD7V5N
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1


(Homo sapiens (Human))
BDBM50193515
PNG
(1-fluoro-(3S)-hydroxyl-4-oleoyloxylbutane 1,3-cycl...)
Show SMILES CCCCCCCCCCCCCCCCCC(=O)OC[C@@H]1CC(F)P(O)(=O)O1
Show InChI InChI=1S/C22H42FO5P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-22(24)27-19-20-18-21(23)29(25,26)28-20/h20-21H,2-19H2,1H3,(H,25,26)/t20-,21?/m0/s1
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60.7n/an/an/an/an/an/an/an/a



The University of Utah

Curated by ChEMBL


Assay Description
Activity at human LPA1 receptor expressed in RH7777 cells by calcium mobilization assay


J Med Chem 49: 5309-15 (2006)


Article DOI: 10.1021/jm060351+
BindingDB Entry DOI: 10.7270/Q2VM4BWW
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1


(Homo sapiens (Human))
BDBM50150014
PNG
(CHEMBL291229 | Phosphoric acid mono-{2-((Z)-(R)-oc...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](COP(O)(O)=O)Cc1ccc(OCc2cc(OCCC)ccn2)cc1
Show InChI InChI=1S/C36H57N2O7P/c1-3-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-36(39)38-33(30-45-46(40,41)42)27-31-20-22-34(23-21-31)44-29-32-28-35(24-25-37-32)43-26-4-2/h11-12,20-25,28,33H,3-10,13-19,26-27,29-30H2,1-2H3,(H,38,39)(H2,40,41,42)/b12-11-/t33-/m1/s1
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64n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Binding affinity towards Lysophosphatidic acid 1 (LPA1) receptor


Bioorg Med Chem Lett 14: 4069-74 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.023
BindingDB Entry DOI: 10.7270/Q2930SM1
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1


(Homo sapiens (Human))
BDBM50146238
PNG
(CHEMBL314554 | Phosphoric acid mono-[(R)-3-[4-(1H-...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](COP(O)(O)=O)Cc1ccc(Oc2cc3ccccc3[nH]2)cc1
Show InChI InChI=1S/C35H51N2O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-21-34(38)36-31(28-42-44(39,40)41)26-29-22-24-32(25-23-29)43-35-27-30-19-17-18-20-33(30)37-35/h9-10,17-20,22-25,27,31,37H,2-8,11-16,21,26,28H2,1H3,(H,36,38)(H2,39,40,41)/b10-9-/t31-/m1/s1
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73n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro ability to antagonize LPA-evoked [35S]-GTP-gammaS binding to lysophosphatidic acid receptor 1 in HEK293T cell lines


Bioorg Med Chem Lett 14: 2735-40 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.076
BindingDB Entry DOI: 10.7270/Q2DF6QN9
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50170849
PNG
(CHEMBL189296 | Thiophosphoric acid tetradecyl este...)
Show SMILES CCCCCCCCCCCCCCOP(O)(O)=S
Show InChI InChI=1S/C14H31O3PS/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-17-18(15,16)19/h2-14H2,1H3,(H2,15,16,19)
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76n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cells


J Med Chem 48: 4919-30 (2005)


Article DOI: 10.1021/jm049609r
BindingDB Entry DOI: 10.7270/Q2HD7V5N
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1/lysophosphatidic acid receptor 3


(Rattus norvegicus)
BDBM50177339
PNG
(CHEMBL436763 | potassium ((2R,4R)-2-(heptadec-9-en...)
Show SMILES CCCCCCC\C=C\CCCCCCCC[C@@H]1OC[C@H](COP(O)([O-])=O)O1
Show InChI InChI=1S/C21H41O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21-25-18-20(27-21)19-26-28(22,23)24/h8-9,20-21H,2-7,10-19H2,1H3,(H2,22,23,24)/p-1/b9-8+/t20-,21-/m1/s1
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83n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Activity at LPA3 receptor in RH7777 rat hepatoma cell line


Bioorg Med Chem Lett 16: 451-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.096
BindingDB Entry DOI: 10.7270/Q2Z89C01
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50150010
PNG
(CHEMBL265967 | Phosphoric acid mono-[(R)-3-[4-(4-m...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](COP(O)(O)=O)Cc1ccc(OCc2cc(OC)ccn2)cc1
Show InChI InChI=1S/C34H53N2O7P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-34(37)36-31(28-43-44(38,39)40)25-29-19-21-32(22-20-29)42-27-30-26-33(41-2)23-24-35-30/h10-11,19-24,26,31H,3-9,12-18,25,27-28H2,1-2H3,(H,36,37)(H2,38,39,40)/b11-10-/t31-/m1/s1
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102n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Binding affinity towards Lysophosphatidic acid 3 (LPA3) receptor


Bioorg Med Chem Lett 14: 4069-74 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.023
BindingDB Entry DOI: 10.7270/Q2930SM1
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50176392
PNG
(CHEMBL379248 | thiophosphoric acid (R)-2-octanoyla...)
Show SMILES CCCCCCCCNC(=O)[C@@H](COP(O)(O)=S)NC(=O)CCCCCCC
Show InChI InChI=1S/C19H39N2O5PS/c1-3-5-7-9-11-13-15-20-19(23)17(16-26-27(24,25)28)21-18(22)14-12-10-8-6-4-2/h17H,3-16H2,1-2H3,(H,20,23)(H,21,22)(H2,24,25,28)/t17-/m1/s1
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118n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Activity at LPA3 receptor transfected RH7777 cells


Bioorg Med Chem Lett 16: 633-40 (2005)


Article DOI: 10.1016/j.bmcl.2005.10.031
BindingDB Entry DOI: 10.7270/Q2ZC82DB
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50176393
PNG
(CHEMBL383095 | octanoic acid (S)-2-octanoyloxy-3-p...)
Show SMILES CCCCCCCC(=O)OC[C@@H](COP(O)(O)=O)OC(=O)CCCCCCC
Show InChI InChI=1S/C19H37O8P/c1-3-5-7-9-11-13-18(20)25-15-17(16-26-28(22,23)24)27-19(21)14-12-10-8-6-4-2/h17H,3-16H2,1-2H3,(H2,22,23,24)/t17-/m0/s1
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119n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Activity at LPA3 receptor transfected RH7777 cells


Bioorg Med Chem Lett 16: 633-40 (2005)


Article DOI: 10.1016/j.bmcl.2005.10.031
BindingDB Entry DOI: 10.7270/Q2ZC82DB
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50170854
PNG
(CHEMBL187711 | Phosphoric acid monododecyl ester)
Show SMILES CCCCCCCCCCCCOP(O)(O)=O
Show InChI InChI=1S/C12H27O4P/c1-2-3-4-5-6-7-8-9-10-11-12-16-17(13,14)15/h2-12H2,1H3,(H2,13,14,15)
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121n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cells


J Med Chem 48: 4919-30 (2005)


Article DOI: 10.1021/jm049609r
BindingDB Entry DOI: 10.7270/Q2HD7V5N
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50170850
PNG
(CHEMBL361255 | Phosphoric acid monodecyl ester)
Show SMILES CCCCCCCCCCOP(O)(O)=O
Show InChI InChI=1S/C10H23O4P/c1-2-3-4-5-6-7-8-9-10-14-15(11,12)13/h2-10H2,1H3,(H2,11,12,13)
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121n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cells


J Med Chem 48: 4919-30 (2005)


Article DOI: 10.1021/jm049609r
BindingDB Entry DOI: 10.7270/Q2HD7V5N
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50170855
PNG
(CHEMBL363935 | Thiophosphoric acid dec-9-enyl este...)
Show SMILES OP(O)(=S)OCCCCCCCCC=C
Show InChI InChI=1S/C10H21O3PS/c1-2-3-4-5-6-7-8-9-10-13-14(11,12)15/h2H,1,3-10H2,(H2,11,12,15)
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128n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cells


J Med Chem 48: 4919-30 (2005)


Article DOI: 10.1021/jm049609r
BindingDB Entry DOI: 10.7270/Q2HD7V5N
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1


(Homo sapiens (Human))
BDBM50146250
PNG
(CHEMBL313413 | Phosphoric acid mono-[(R)-3-[4-(ind...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](COP(O)(O)=O)Cc1ccc(OC2Cc3ccccc3C2)cc1
Show InChI InChI=1S/C36H54NO6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-21-36(38)37-33(29-42-44(39,40)41)26-30-22-24-34(25-23-30)43-35-27-31-19-17-18-20-32(31)28-35/h9-10,17-20,22-25,33,35H,2-8,11-16,21,26-29H2,1H3,(H,37,38)(H2,39,40,41)/b10-9-/t33-/m1/s1
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134n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro ability to antagonize LPA-evoked [35S]-GTP-gammaS binding to lysophosphatidic acid receptor 1 in HEK293T cell lines


Bioorg Med Chem Lett 14: 2735-40 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.076
BindingDB Entry DOI: 10.7270/Q2DF6QN9
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1


(Homo sapiens (Human))
BDBM50146237
PNG
(CHEMBL262906 | Phosphoric acid mono-[3-(4-benzylox...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)NC(COP(O)(O)=O)Cc1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C34H52NO6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-34(36)35-32(29-41-42(37,38)39)27-30-23-25-33(26-24-30)40-28-31-20-17-16-18-21-31/h9-10,16-18,20-21,23-26,32H,2-8,11-15,19,22,27-29H2,1H3,(H,35,36)(H2,37,38,39)/b10-9-
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137n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro ability to antagonize LPA-evoked [35S]-GTP-gammaS binding to lysophosphatidic acid receptor 1 in HEK293T cell lines


Bioorg Med Chem Lett 14: 2735-40 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.076
BindingDB Entry DOI: 10.7270/Q2DF6QN9
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1


(Homo sapiens (Human))
BDBM50176398
PNG
((S)-O-2,3-bis(octyloxy)propyl O,O-dihydrogen phosp...)
Show SMILES CCCCCCCCOC[C@@H](COP(O)(O)=S)OCCCCCCCC
Show InChI InChI=1S/C19H41O5PS/c1-3-5-7-9-11-13-15-22-17-19(18-24-25(20,21)26)23-16-14-12-10-8-6-4-2/h19H,3-18H2,1-2H3,(H2,20,21,26)/t19-/m0/s1
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139n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Activity at LPA1 receptor transfected RH7777 cells


Bioorg Med Chem Lett 16: 633-40 (2005)


Article DOI: 10.1016/j.bmcl.2005.10.031
BindingDB Entry DOI: 10.7270/Q2ZC82DB
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50170859
PNG
(3-(4-(4-((1-(2-chlorophenyl)ethoxy)carbonyl)-3-met...)
Show SMILES CC(OC(=O)Nc1c(C)noc1-c1ccc(CSCCC(O)=O)cc1)c1ccccc1Cl
Show InChI InChI=1S/C23H23ClN2O5S/c1-14-21(25-23(29)30-15(2)18-5-3-4-6-19(18)24)22(31-26-14)17-9-7-16(8-10-17)13-32-12-11-20(27)28/h3-10,15H,11-13H2,1-2H3,(H,25,29)(H,27,28)
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148n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cells


J Med Chem 48: 4919-30 (2005)


Article DOI: 10.1021/jm049609r
BindingDB Entry DOI: 10.7270/Q2HD7V5N
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50150008
PNG
(CHEMBL182773 | [4-[4-(4-Methoxy-3,5-dimethyl-pyrid...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](CCP(O)(O)=O)Cc1ccc(OCc2ncc(C)c(OC)c2C)cc1
Show InChI InChI=1S/C37H59N2O6P/c1-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-36(40)39-33(25-26-46(41,42)43)27-32-21-23-34(24-22-32)45-29-35-31(3)37(44-4)30(2)28-38-35/h12-13,21-24,28,33H,5-11,14-20,25-27,29H2,1-4H3,(H,39,40)(H2,41,42,43)/b13-12-/t33-/m0/s1
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150n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Binding affinity towards Lysophosphatidic acid 3 (LPA3) receptor


Bioorg Med Chem Lett 14: 4069-74 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.023
BindingDB Entry DOI: 10.7270/Q2930SM1
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1


(Homo sapiens (Human))
BDBM50146230
PNG
(CHEMBL314555 | Phosphoric acid mono-{(S)-2-((Z)-oc...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](COP(O)(O)=O)Cc1ccc(OCc2ccccn2)cc1
Show InChI InChI=1S/C33H51N2O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-33(36)35-31(28-41-42(37,38)39)26-29-21-23-32(24-22-29)40-27-30-19-17-18-25-34-30/h9-10,17-19,21-25,31H,2-8,11-16,20,26-28H2,1H3,(H,35,36)(H2,37,38,39)/b10-9-/t31-/m0/s1
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156n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
In vitro ability to antagonize LPA-evoked [35S]-GTP-gammaS binding to lysophosphatidic acid receptor 1 in HEK293T cell lines


Bioorg Med Chem Lett 14: 2735-40 (2004)


Article DOI: 10.1016/j.bmcl.2004.03.076
BindingDB Entry DOI: 10.7270/Q2DF6QN9
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1


(Homo sapiens (Human))
BDBM50146230
PNG
(CHEMBL314555 | Phosphoric acid mono-{(S)-2-((Z)-oc...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](COP(O)(O)=O)Cc1ccc(OCc2ccccn2)cc1
Show InChI InChI=1S/C33H51N2O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-33(36)35-31(28-41-42(37,38)39)26-29-21-23-32(24-22-29)40-27-30-19-17-18-25-34-30/h9-10,17-19,21-25,31H,2-8,11-16,20,26-28H2,1H3,(H,35,36)(H2,37,38,39)/b10-9-/t31-/m0/s1
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156n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Binding affinity towards Lysophosphatidic acid 1 (LPA1) receptor


Bioorg Med Chem Lett 14: 4069-74 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.023
BindingDB Entry DOI: 10.7270/Q2930SM1
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1/lysophosphatidic acid receptor 3


(Rattus norvegicus)
BDBM50177329
PNG
(CHEMBL199380 | potassium (2-(6-(4-octylphenyl)hexy...)
Show SMILES CCCCCCCCc1ccc(CCCCCCC2OCC(COP(O)([O-])=O)O2)cc1
Show InChI InChI=1S/C24H41O6P/c1-2-3-4-5-6-9-12-21-15-17-22(18-16-21)13-10-7-8-11-14-24-28-19-23(30-24)20-29-31(25,26)27/h15-18,23-24H,2-14,19-20H2,1H3,(H2,25,26,27)/p-1
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171n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Activity at LPA3 receptor in RH7777 rat hepatoma cell line


Bioorg Med Chem Lett 16: 451-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.096
BindingDB Entry DOI: 10.7270/Q2Z89C01
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50146232
PNG
(CHEMBL440696 | Phosphoric acid mono-{(R)-2-((Z)-oc...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@@H](COP(O)(O)=O)Cc1ccc(OCc2ccccn2)cc1
Show InChI InChI=1S/C33H51N2O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-33(36)35-31(28-41-42(37,38)39)26-29-21-23-32(24-22-29)40-27-30-19-17-18-25-34-30/h9-10,17-19,21-25,31H,2-8,11-16,20,26-28H2,1H3,(H,35,36)(H2,37,38,39)/b10-9-/t31-/m1/s1
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175n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Binding affinity towards Lysophosphatidic acid 3 (LPA3) receptor


Bioorg Med Chem Lett 14: 4069-74 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.023
BindingDB Entry DOI: 10.7270/Q2930SM1
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50176396
PNG
(CHEMBL204037 | Serine amide phospate derivative | ...)
Show SMILES CCCCCCCCNC(=O)[C@H](COP(O)(O)=O)NC(=O)CCCCCCC
Show InChI InChI=1S/C19H39N2O6P/c1-3-5-7-9-11-13-15-20-19(23)17(16-27-28(24,25)26)21-18(22)14-12-10-8-6-4-2/h17H,3-16H2,1-2H3,(H,20,23)(H,21,22)(H2,24,25,26)/t17-/m0/s1
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196n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Activity at LPA3 receptor transfected RH7777 cells


Bioorg Med Chem Lett 16: 633-40 (2005)


Article DOI: 10.1016/j.bmcl.2005.10.031
BindingDB Entry DOI: 10.7270/Q2ZC82DB
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50170862
PNG
(CHEMBL191055 | Octanoic acid (S)-1-methyl-2-octano...)
Show SMILES CCCCCCCC(=O)OC[C@H](COP(O)(=O)OP(O)(O)=O)OC(=O)CCCCCCC
Show InChI InChI=1S/C19H38O11P2/c1-3-5-7-9-11-13-18(20)27-15-17(16-28-32(25,26)30-31(22,23)24)29-19(21)14-12-10-8-6-4-2/h17H,3-16H2,1-2H3,(H,25,26)(H2,22,23,24)/t17-/m1/s1
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202n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cells


J Med Chem 48: 4919-30 (2005)


Article DOI: 10.1021/jm049609r
BindingDB Entry DOI: 10.7270/Q2HD7V5N
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50170842
PNG
(CHEMBL187633 | Phosphoric acid monotetradecyl este...)
Show SMILES CCCCCCCCCCCCCCOP(O)(O)=O
Show InChI InChI=1S/C14H31O4P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-18-19(15,16)17/h2-14H2,1H3,(H2,15,16,17)
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211n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cells


J Med Chem 48: 4919-30 (2005)


Article DOI: 10.1021/jm049609r
BindingDB Entry DOI: 10.7270/Q2HD7V5N
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1


(Homo sapiens (Human))
BDBM50176393
PNG
(CHEMBL383095 | octanoic acid (S)-2-octanoyloxy-3-p...)
Show SMILES CCCCCCCC(=O)OC[C@@H](COP(O)(O)=O)OC(=O)CCCCCCC
Show InChI InChI=1S/C19H37O8P/c1-3-5-7-9-11-13-18(20)25-15-17(16-26-28(22,23)24)27-19(21)14-12-10-8-6-4-2/h17H,3-16H2,1-2H3,(H2,22,23,24)/t17-/m0/s1
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221n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Activity at LPA1 receptor transfected RH7777 cells


Bioorg Med Chem Lett 16: 633-40 (2005)


Article DOI: 10.1016/j.bmcl.2005.10.031
BindingDB Entry DOI: 10.7270/Q2ZC82DB
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50304580
PNG
(2-(3-(4-nitrophenoxy)phenyl)-1,3-dioxoisoindoline-...)
Show SMILES OC(=O)c1ccc2C(=O)N(C(=O)c2c1)c1cccc(Oc2ccc(cc2)[N+]([O-])=O)c1
Show InChI InChI=1S/C21H12N2O7/c24-19-17-9-4-12(21(26)27)10-18(17)20(25)22(19)14-2-1-3-16(11-14)30-15-7-5-13(6-8-15)23(28)29/h1-11H,(H,26,27)
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230n/an/an/an/an/an/an/an/a



The University of Memphis

Curated by ChEMBL


Assay Description
Binding affinity to LPA3


Bioorg Med Chem 17: 7457-64 (2009)


Article DOI: 10.1016/j.bmc.2009.09.022
BindingDB Entry DOI: 10.7270/Q2GB244M
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50149993
PNG
(CHEMBL181612 | [4-(4-Benzyloxy-phenyl)-1-hydroxy-3...)
Show SMILES CCCCCCCC\C=C/CCCCCCCC(=O)N[C@H](CC(=O)P(O)(O)O)Cc1ccc(OCc2ccccc2)cc1
Show InChI InChI=1S/C35H54NO6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-34(37)36-32(28-35(38)43(39,40)41)27-30-23-25-33(26-24-30)42-29-31-20-17-16-18-21-31/h9-10,16-18,20-21,23-26,32,39-41,43H,2-8,11-15,19,22,27-29H2,1H3,(H,36,37)/b10-9-/t32-/m0/s1
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232n/an/an/an/an/an/an/an/a



University of Virginia

Curated by ChEMBL


Assay Description
Binding affinity towards Lysophosphatidic acid 3 (LPA3) receptor


Bioorg Med Chem Lett 14: 4069-74 (2004)


Article DOI: 10.1016/j.bmcl.2004.05.023
BindingDB Entry DOI: 10.7270/Q2930SM1
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 1/lysophosphatidic acid receptor 3


(Rattus norvegicus)
BDBM50177340
PNG
(CHEMBL382116 | potassium ((2R,4S)-2-(heptadec-9-en...)
Show SMILES CCCCCCC\C=C\CCCCCCCC[C@@H]1OC[C@@H](COP(O)([O-])=O)O1
Show InChI InChI=1S/C21H41O6P/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21-25-18-20(27-21)19-26-28(22,23)24/h8-9,20-21H,2-7,10-19H2,1H3,(H2,22,23,24)/p-1/b9-8+/t20-,21+/m0/s1
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241n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Activity at LPA3 receptor in RH7777 rat hepatoma cell line


Bioorg Med Chem Lett 16: 451-6 (2005)


Article DOI: 10.1016/j.bmcl.2005.08.096
BindingDB Entry DOI: 10.7270/Q2Z89C01
More data for this
Ligand-Target Pair
Lysophosphatidic acid receptor 3 (LPAR3)


(Homo sapiens (Human))
BDBM50170845
PNG
(CHEMBL363067 | Dodecyl-phosphonic acid)
Show SMILES CCCCCCCCCCCCP(O)(O)=O
Show InChI InChI=1S/C12H27O3P/c1-2-3-4-5-6-7-8-9-10-11-12-16(13,14)15/h2-12H2,1H3,(H2,13,14,15)
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303n/an/an/an/an/an/an/an/a



University of Tennessee Health Science Center

Curated by ChEMBL


Assay Description
Binding affinity for Lysophosphatidic acid receptor 3 expressed in RH7777 rat hepatoma cells


J Med Chem 48: 4919-30 (2005)


Article DOI: 10.1021/jm049609r
BindingDB Entry DOI: 10.7270/Q2HD7V5N
More data for this
Ligand-Target Pair
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