Compile Data Set for Download or QSAR

Found 416 hits Enz. Inhib. hit(s) with Target = 'Monoglyceride lipase (MGL)'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Monoglyceride lipase (MGL) (Rattus norvegicus (Rat))	BDBM50274152 ((2S,9Z)-octadec-9-ene-1,2-diamine dihydrochloride ...) Show SMILES CCCCCCCC\C=C/CCCCCC[C@H](N)CN Show InChI InChI=1S/C18H38N2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18(20)17-19/h9-10,18H,2-8,11-17,19-20H2,1H3/b10-9-/t18-/m0/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	2.18E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Sprague-Dawley rat MGL				Bioorg Med Chem Lett 18: 5424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.09.039 BindingDB Entry DOI: 10.7270/Q2VM4C30
					More data for this Ligand-Target Pair
Monoglyceride lipase (MGL) (Rattus norvegicus (Rat))	BDBM50274153 ((2R,9Z)-octadec-9-ene-1,2-diamine dihydrochloride ...) Show SMILES CCCCCCCC\C=C/CCCCCC[C@@H](N)CN Show InChI InChI=1S/C18H38N2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18(20)17-19/h9-10,18H,2-8,11-17,19-20H2,1H3/b10-9-/t18-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	3.90E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Sprague-Dawley rat MGL				Bioorg Med Chem Lett 18: 5424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.09.039 BindingDB Entry DOI: 10.7270/Q2VM4C30
					More data for this Ligand-Target Pair
Monoglyceride lipase (MGL) (Rattus norvegicus (Rat))	BDBM50274151 (CHEMBL473249 | hexadecane-1,2-diamine dihydrochlor...) Show SMILES CCCCCCCCCCCCCCC(N)CN Show InChI InChI=1S/C16H36N2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16(18)15-17/h16H,2-15,17-18H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.87E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
University of Athens Curated by ChEMBL					Assay Description Inhibition of Sprague-Dawley rat MGL				Bioorg Med Chem Lett 18: 5424-7 (2008) Article DOI: 10.1016/j.bmcl.2008.09.039 BindingDB Entry DOI: 10.7270/Q2VM4C30
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50247050 (4-cyanophenyl ethyl dodecylphosphonate | CHEMBL462...) Show SMILES CCCCCCCCCCCCP(=O)(OCC)Oc1ccc(cc1)C#N Show InChI InChI=1S/C21H34NO3P/c1-3-5-6-7-8-9-10-11-12-13-18-26(23,24-4-2)25-21-16-14-20(19-22)15-17-21/h14-17H,3-13,18H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.0700	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brain				Bioorg Med Chem Lett 18: 5875-8 (2008) Article DOI: 10.1016/j.bmcl.2008.08.007 BindingDB Entry DOI: 10.7270/Q2S75G4N
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50247049 (CHEMBL462610 | ethyl 3,5,6-trichloropyridin-2-yl d...) Show SMILES CCCCCCCCCCCCP(=O)(OCC)Oc1nc(Cl)c(Cl)cc1Cl Show InChI InChI=1S/C19H31Cl3NO3P/c1-3-5-6-7-8-9-10-11-12-13-14-27(24,25-4-2)26-19-17(21)15-16(20)18(22)23-19/h15H,3-14H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.140	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brain				Bioorg Med Chem Lett 18: 5875-8 (2008) Article DOI: 10.1016/j.bmcl.2008.08.007 BindingDB Entry DOI: 10.7270/Q2S75G4N
					More data for this Ligand-Target Pair
Monoglyceride lipase (MGL) (Rattus norvegicus (Rat))	BDBM50160284 (CHEMBL3785379) Show SMILES Fc1ccc(cc1)[C@@H]1[C@H](N(C2CCN(CC2)C(=O)n2cncn2)C1=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C24H22FN5O4/c25-17-4-1-15(2-5-17)21-22(16-3-6-19-20(11-16)34-14-33-19)30(23(21)31)18-7-9-28(10-8-18)24(32)29-13-26-12-27-29/h1-6,11-13,18,21-22H,7-10,14H2/t21-,22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.25	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of rat MAGL				J Med Chem 59: 2612-32 (2016) Article DOI: 10.1021/acs.jmedchem.5b01812 BindingDB Entry DOI: 10.7270/Q21R6SC7
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50247051 (CHEMBL512224 | isopropyl 4-nitrophenyl dodecylphos...) Show SMILES CCCCCCCCCCCCP(=O)(OC(C)C)Oc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C21H36NO5P/c1-4-5-6-7-8-9-10-11-12-13-18-28(25,26-19(2)3)27-21-16-14-20(15-17-21)22(23)24/h14-17,19H,4-13,18H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.280	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brain				Bioorg Med Chem Lett 18: 5875-8 (2008) Article DOI: 10.1016/j.bmcl.2008.08.007 BindingDB Entry DOI: 10.7270/Q2S75G4N
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50247052 (2-Nonylsulfanyl-4H-benzo[1,3,2]dioxaphosphinine 2-...) Show SMILES CCCCCCCCCSP1(=O)OCc2ccccc2O1 Show InChI InChI=1S/C16H25O3PS/c1-2-3-4-5-6-7-10-13-21-20(17)18-14-15-11-8-9-12-16(15)19-20/h8-9,11-12H,2-7,10,13-14H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	0.310	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brain				Bioorg Med Chem Lett 18: 5875-8 (2008) Article DOI: 10.1016/j.bmcl.2008.08.007 BindingDB Entry DOI: 10.7270/Q2S75G4N
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50132717 (CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...) Show SMILES CCCCCCCCCCCCP(F)(=O)OC(C)C Show InChI InChI=1S/C15H32FO2P/c1-4-5-6-7-8-9-10-11-12-13-14-19(16,17)18-15(2)3/h15H,4-14H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Displacement of 2-arachidonylglycerol from MAGL in Swiss Webster mouse brain after 5 mins				Nat Chem Biol 4: 373-8 (2008) Article DOI: 10.1038/nchembio.86 BindingDB Entry DOI: 10.7270/Q2SX6DF4
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50132717 (CHEMBL333149 | Isopropyl dodecylfluorophosphonate ...) Show SMILES CCCCCCCCCCCCP(F)(=O)OC(C)C Show InChI InChI=1S/C15H32FO2P/c1-4-5-6-7-8-9-10-11-12-13-14-19(16,17)18-15(2)3/h15H,4-14H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	0.800	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brain				Bioorg Med Chem Lett 18: 5875-8 (2008) Article DOI: 10.1016/j.bmcl.2008.08.007 BindingDB Entry DOI: 10.7270/Q2S75G4N
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50247048 (CHEMBL462609 | methyl icosylphosphonofluoridate) Show SMILES CCCCCCCCCCCCCCCCCCCCP(F)(=O)OC Show InChI InChI=1S/C21H44FO2P/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25(22,23)24-2/h3-21H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.20	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brain				Bioorg Med Chem Lett 18: 5875-8 (2008) Article DOI: 10.1016/j.bmcl.2008.08.007 BindingDB Entry DOI: 10.7270/Q2S75G4N
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50324698 (CHEMBL1222256 | Ethyl octylfluorophosphonate) Show SMILES CCCCCCCCP(F)(=O)OC(C)C Show InChI InChI=1S/C11H24FO2P/c1-4-5-6-7-8-9-10-15(12,13)14-11(2)3/h11H,4-10H2,1-3H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Displacement of 2-arachidonylglycerol from MAGL in Swiss Webster mouse brain after 5 mins				Nat Chem Biol 4: 373-8 (2008) Article DOI: 10.1038/nchembio.86 BindingDB Entry DOI: 10.7270/Q2SX6DF4
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM26736 (CHEMBL509860 | LY2183240 | N,N-dimethyl-5-[(4-phen...) Show SMILES CN(C)C(=O)n1nnnc1Cc1ccc(cc1)-c1ccccc1 Show InChI InChI=1S/C17H17N5O/c1-21(2)17(23)22-16(18-19-20-22)12-13-8-10-15(11-9-13)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	5.30	n/a	n/a	n/a	n/a	7.4	22
The Scripps Research Institute					Assay Description Serine hydrolase targets were recombinantly expressed in COS-7 cells by transient transfection. IC50 values were obtained by competitive ABPP with F...				J Am Chem Soc 128: 9699-704 (2006) Article DOI: 10.1021/ja062999h BindingDB Entry DOI: 10.7270/Q20K26VX
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM60622 (BDBM50300355 | US9133148, A) Show SMILES OC(C1CCN(CC1)C(=O)Oc1ccc(cc1)[N+]([O-])=O)(c1ccc2OCOc2c1)c1ccc2OCOc2c1 Show InChI InChI=1S/C27H24N2O9/c30-26(38-21-5-3-20(4-6-21)29(32)33)28-11-9-17(10-12-28)27(31,18-1-7-22-24(13-18)36-15-34-22)19-2-8-23-25(14-19)37-16-35-23/h1-8,13-14,17,31H,9-12,15-16H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	6	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brain membranes preincubated for 30 mins				Eur J Med Chem 63: 64-75 (2013) Article DOI: 10.1016/j.ejmech.2013.01.050 BindingDB Entry DOI: 10.7270/Q2377B2N
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM60622 (BDBM50300355 | US9133148, A) Show SMILES OC(C1CCN(CC1)C(=O)Oc1ccc(cc1)[N+]([O-])=O)(c1ccc2OCOc2c1)c1ccc2OCOc2c1 Show InChI InChI=1S/C27H24N2O9/c30-26(38-21-5-3-20(4-6-21)29(32)33)28-11-9-17(10-12-28)27(31,18-1-7-22-24(13-18)36-15-34-22)19-2-8-23-25(14-19)37-16-35-23/h1-8,13-14,17,31H,9-12,15-16H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
Monash University (Parkville Campus) Curated by ChEMBL					Assay Description Inhibition of mouse recombinant MAGL expressed in african green monkey COS7 cells assessed as inhibition of 2-AG hydrolysis after 30 mins by LC-MS an...				Bioorg Med Chem Lett 21: 6782-7 (2011) Article DOI: 10.1016/j.bmcl.2011.09.038 BindingDB Entry DOI: 10.7270/Q2TH8N3G
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM60622 (BDBM50300355 | US9133148, A) Show SMILES OC(C1CCN(CC1)C(=O)Oc1ccc(cc1)[N+]([O-])=O)(c1ccc2OCOc2c1)c1ccc2OCOc2c1 Show InChI InChI=1S/C27H24N2O9/c30-26(38-21-5-3-20(4-6-21)29(32)33)28-11-9-17(10-12-28)27(31,18-1-7-22-24(13-18)36-15-34-22)19-2-8-23-25(14-19)37-16-35-23/h1-8,13-14,17,31H,9-12,15-16H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	8	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAGL in C57B1/6J mouse brain membrane after 30 mins by using 2-AG as a substrate by LC-MS method				Nat Chem Biol 5: 37-44 (2008) Article DOI: 10.1038/nchembio.129 BindingDB Entry DOI: 10.7270/Q2DN4582
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50307065 (4-Nitrophenyl 4-((4-Phenylthiophen-2-yl)methyl)pip...) Show SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3cc(cs3)-c3ccccc3)CC2)cc1 Show InChI InChI=1S/C22H21N3O4S/c26-22(29-20-8-6-19(7-9-20)25(27)28)24-12-10-23(11-13-24)15-21-14-18(16-30-21)17-4-2-1-3-5-17/h1-9,14,16H,10-13,15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAGL in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM60622 (BDBM50300355 | US9133148, A) Show SMILES OC(C1CCN(CC1)C(=O)Oc1ccc(cc1)[N+]([O-])=O)(c1ccc2OCOc2c1)c1ccc2OCOc2c1 Show InChI InChI=1S/C27H24N2O9/c30-26(38-21-5-3-20(4-6-21)29(32)33)28-11-9-17(10-12-28)27(31,18-1-7-22-24(13-18)36-15-34-22)19-2-8-23-25(14-19)37-16-35-23/h1-8,13-14,17,31H,9-12,15-16H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAGL in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50247086 (CHEMBL444970 | Chlorphrifos oxon | diethyl 3,5,6-t...) Show SMILES CCOP(=O)(OCC)Oc1nc(Cl)c(Cl)cc1Cl Show InChI InChI=1S/C9H11Cl3NO4P/c1-3-15-18(14,16-4-2)17-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of MAGL-mediated 2-arachidonoylglycerol hydrolysis in mouse brain				Bioorg Med Chem Lett 18: 5875-8 (2008) Article DOI: 10.1016/j.bmcl.2008.08.007 BindingDB Entry DOI: 10.7270/Q2S75G4N
					More data for this Ligand-Target Pair
Monoglyceride lipase (MGL) (Rattus norvegicus (Rat))	BDBM50160284 (CHEMBL3785379) Show SMILES Fc1ccc(cc1)[C@@H]1[C@H](N(C2CCN(CC2)C(=O)n2cncn2)C1=O)c1ccc2OCOc2c1 Show InChI InChI=1S/C24H22FN5O4/c25-17-4-1-15(2-5-17)21-22(16-3-6-19-20(11-16)34-14-33-19)30(23(21)31)18-7-9-28(10-8-18)24(32)29-13-26-12-27-29/h1-6,11-13,18,21-22H,7-10,14H2/t21-,22-/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of Siena Curated by ChEMBL					Assay Description Inhibition of MAGL in rat brain membranes preincubated for 20 mins followed by fluorophosphonate-rhodamine addition measured after 30 mins by competi...				J Med Chem 59: 2612-32 (2016) Article DOI: 10.1021/acs.jmedchem.5b01812 BindingDB Entry DOI: 10.7270/Q21R6SC7
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50247086 (CHEMBL444970 | Chlorphrifos oxon | diethyl 3,5,6-t...) Show SMILES CCOP(=O)(OCC)Oc1nc(Cl)c(Cl)cc1Cl Show InChI InChI=1S/C9H11Cl3NO4P/c1-3-15-18(14,16-4-2)17-9-7(11)5-6(10)8(12)13-9/h5H,3-4H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	10	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Displacement of 2-arachidonylglycerol from MAGL in Swiss Webster mouse brain after 5 mins				Nat Chem Biol 4: 373-8 (2008) Article DOI: 10.1038/nchembio.86 BindingDB Entry DOI: 10.7270/Q2SX6DF4
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50307072 (4-Nitrophenyl 4-(Biphenyl-4-ylmethyl)piperazine-1-...) Show SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3ccc(cc3)-c3ccccc3)CC2)cc1 Show InChI InChI=1S/C24H23N3O4/c28-24(31-23-12-10-22(11-13-23)27(29)30)26-16-14-25(15-17-26)18-19-6-8-21(9-7-19)20-4-2-1-3-5-20/h1-13H,14-18H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	15	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAGL in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50350559 (CHEMBL1812718) Show SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCC(Cc3cccc(Oc4ccccc4)c3)CC2)cc1 Show InChI InChI=1S/C25H24N2O5/c28-25(32-23-11-9-21(10-12-23)27(29)30)26-15-13-19(14-16-26)17-20-5-4-8-24(18-20)31-22-6-2-1-3-7-22/h1-12,18-19H,13-17H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of mouse MAGL				Bioorg Med Chem Lett 21: 4674-85 (2011) Article DOI: 10.1016/j.bmcl.2011.06.096 BindingDB Entry DOI: 10.7270/Q2W959JK
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50307083 (4-nitrophenyl 4-(3-phenoxybenzyl)piperazine-1-carb...) Show SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3cccc(Oc4ccccc4)c3)CC2)cc1 Show InChI InChI=1S/C24H23N3O5/c28-24(32-22-11-9-20(10-12-22)27(29)30)26-15-13-25(14-16-26)18-19-5-4-8-23(17-19)31-21-6-2-1-3-7-21/h1-12,17H,13-16,18H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	19	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAGL in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoglyceride lipase (MGL) (Rattus norvegicus (Rat))	BDBM60622 (BDBM50300355 | US9133148, A) Show SMILES OC(C1CCN(CC1)C(=O)Oc1ccc(cc1)[N+]([O-])=O)(c1ccc2OCOc2c1)c1ccc2OCOc2c1 Show InChI InChI=1S/C27H24N2O9/c30-26(38-21-5-3-20(4-6-21)29(32)33)28-11-9-17(10-12-28)27(31,18-1-7-22-24(13-18)36-15-34-22)19-2-8-23-25(14-19)37-16-35-23/h1-8,13-14,17,31H,9-12,15-16H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	25	n/a	n/a	n/a	n/a	n/a	n/a
University of M£nster Curated by ChEMBL					Assay Description Inhibition of rat MAGL expressed in monkey COS7 cells				Eur J Med Chem 63: 64-75 (2013) Article DOI: 10.1016/j.ejmech.2013.01.050 BindingDB Entry DOI: 10.7270/Q2377B2N
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50307073 (4-nitrophenyl 4-(hydroxybis(4-methoxyphenyl)methyl...) Show SMILES COc1ccc(cc1)C(O)(C1CCN(CC1)C(=O)Oc1ccc(cc1)[N+]([O-])=O)c1ccc(OC)cc1 Show InChI InChI=1S/C27H28N2O7/c1-34-23-9-3-19(4-10-23)27(31,20-5-11-24(35-2)12-6-20)21-15-17-28(18-16-21)26(30)36-25-13-7-22(8-14-25)29(32)33/h3-14,21,31H,15-18H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAGL in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50307086 (4-Nitrophenyl 4-(3-(Pyridin-2-yloxy)benzyl)piperaz...) Show SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3cccc(Oc4ccccn4)c3)CC2)cc1 Show InChI InChI=1S/C23H22N4O5/c28-23(32-20-9-7-19(8-10-20)27(29)30)26-14-12-25(13-15-26)17-18-4-3-5-21(16-18)31-22-6-1-2-11-24-22/h1-11,16H,12-15,17H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAGL in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50307085 (4-Nitrophenyl 4-((5-Phenylthiophen-2-yl)methyl)pip...) Show SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3ccc(s3)-c3ccccc3)CC2)cc1 Show InChI InChI=1S/C22H21N3O4S/c26-22(29-19-8-6-18(7-9-19)25(27)28)24-14-12-23(13-15-24)16-20-10-11-21(30-20)17-4-2-1-3-5-17/h1-11H,12-16H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAGL in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoglyceride lipase (MGL) (Rattus norvegicus (Rat))	BDBM50359050 (CHEMBL1922513) Show SMILES CCCCCCCCn1sc2ccccc2c1=O Show InChI InChI=1S/C15H21NOS/c1-2-3-4-5-6-9-12-16-15(17)13-10-7-8-11-14(13)18-16/h7-8,10-11H,2-6,9,12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	59	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ catholique de Louvain Curated by ChEMBL					Assay Description Inhibition of rat recombinant N-terminal his-tagged MAGL expressed in Escherichia coli DH5alpha assessed as 2-oleoylglycerol hydrolysis after 10 mins...				Bioorg Med Chem Lett 21: 7321-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.026 BindingDB Entry DOI: 10.7270/Q2B27VPC
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50307087 (4-Nitrophenyl 4-(Naphthalen-2-ylmethyl)piperazine-...) Show SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3ccc4ccccc4c3)CC2)cc1 Show InChI InChI=1S/C22H21N3O4/c26-22(29-21-9-7-20(8-10-21)25(27)28)24-13-11-23(12-14-24)16-17-5-6-18-3-1-2-4-19(18)15-17/h1-10,15H,11-14,16H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAGL in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50247050 (4-cyanophenyl ethyl dodecylphosphonate | CHEMBL462...) Show SMILES CCCCCCCCCCCCP(=O)(OCC)Oc1ccc(cc1)C#N Show InChI InChI=1S/C21H34NO3P/c1-3-5-6-7-8-9-10-11-12-13-18-26(23,24-4-2)25-21-16-14-20(19-22)15-17-21/h14-17H,3-13,18H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
University of California Curated by ChEMBL					Assay Description Inhibition of MAGL-mediated [14C]1-oleoylglycerol hydrolysis in mouse brain				Bioorg Med Chem Lett 18: 5875-8 (2008) Article DOI: 10.1016/j.bmcl.2008.08.007 BindingDB Entry DOI: 10.7270/Q2S75G4N
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50307081 (4-Nitrophenyl 4-((5-(2-(Trifluoromethoxy)phenyl)fu...) Show SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3ccc(o3)-c3ccccc3OC(F)(F)F)CC2)cc1 Show InChI InChI=1S/C23H20F3N3O6/c24-23(25,26)35-21-4-2-1-3-19(21)20-10-9-18(33-20)15-27-11-13-28(14-12-27)22(30)34-17-7-5-16(6-8-17)29(31)32/h1-10H,11-15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAGL in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50307061 (4-Nitrophenyl 4-(Hydroxybis(4-methoxyphenyl)methyl...) Show SMILES COc1ccc(cc1)C(C1CCN(CC1)C(=O)Oc1ccc(cc1)[N+]([O-])=O)c1ccc(OC)cc1 Show InChI InChI=1S/C27H28N2O6/c1-33-23-9-3-19(4-10-23)26(20-5-11-24(34-2)12-6-20)21-15-17-28(18-16-21)27(30)35-25-13-7-22(8-14-25)29(31)32/h3-14,21,26H,15-18H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	73	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAGL in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50307060 (4-Nitrophenyl 4-(Quinolin-2-ylmethyl)piperazine-1-...) Show SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3ccc4ccccc4n3)CC2)cc1 Show InChI InChI=1S/C21H20N4O4/c26-21(29-19-9-7-18(8-10-19)25(27)28)24-13-11-23(12-14-24)15-17-6-5-16-3-1-2-4-20(16)22-17/h1-10H,11-15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAGL in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoglyceride lipase (MGL) (Rattus norvegicus (Rat))	BDBM50359049 (CHEMBL1922512) Show SMILES CCCCCCCCN1SCCC1=O Show InChI InChI=1S/C11H21NOS/c1-2-3-4-5-6-7-9-12-11(13)8-10-14-12/h2-10H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Patents	Article PubMed	n/a	n/a	88	n/a	n/a	n/a	n/a	n/a	n/a
Universit£ catholique de Louvain Curated by ChEMBL					Assay Description Inhibition of rat recombinant N-terminal his-tagged MAGL expressed in Escherichia coli DH5alpha assessed as 2-oleoylglycerol hydrolysis after 10 mins...				Bioorg Med Chem Lett 21: 7321-4 (2011) Article DOI: 10.1016/j.bmcl.2011.10.026 BindingDB Entry DOI: 10.7270/Q2B27VPC
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50307084 (4-Nitrophenyl 4-((5-Phenylfuran-2-yl)methyl)pipera...) Show SMILES [O-][N+](=O)c1ccc(OC(=O)N2CCN(Cc3ccc(o3)-c3ccccc3)CC2)cc1 Show InChI InChI=1S/C22H21N3O5/c26-22(30-19-8-6-18(7-9-19)25(27)28)24-14-12-23(13-15-24)16-20-10-11-21(29-20)17-4-2-1-3-5-17/h1-11H,12-16H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAGL in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50307088 (4-Nitrophenyl 4-(5-Bromo-2-hydroxybenzyl)piperazin...) Show SMILES Oc1ccc(Br)cc1CN1CCN(CC1)C(=O)Oc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C18H18BrN3O5/c19-14-1-6-17(23)13(11-14)12-20-7-9-21(10-8-20)18(24)27-16-4-2-15(3-5-16)22(25)26/h1-6,11,23H,7-10,12H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAGL in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM50307089 (4-Nitrophenyl 4-(4-(Benzyloxy)-2-methoxybenzyl)pip...) Show SMILES COc1cc(OCc2ccccc2)ccc1CN1CCN(CC1)C(=O)Oc1ccc(cc1)[N+]([O-])=O Show InChI InChI=1S/C26H27N3O6/c1-33-25-17-24(34-19-20-5-3-2-4-6-20)10-7-21(25)18-27-13-15-28(16-14-27)26(30)35-23-11-8-22(9-12-23)29(31)32/h2-12,17H,13-16,18-19H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
The Scripps Research Institute Curated by ChEMBL					Assay Description Inhibition of MAGL in mouse brain membrane				J Med Chem 53: 1830-42 (2010) Article DOI: 10.1021/jm9016976 BindingDB Entry DOI: 10.7270/Q2KH0NFR
					More data for this Ligand-Target Pair
Monoglyceride lipase (MGL) (Rattus norvegicus (Rat))	BDBM81363 (Pristimerin) Show SMILES COC(=O)[C@]1(C)CC[C@]2(C)CC[C@]3(C)C4=CC=c5c(cc(O)c(O)c5=C)[C@]4(C)CC[C@@]3(C)C2C1 Show InChI InChI=1S/C30H40O4/c1-18-19-8-9-22-28(4,20(19)16-21(31)24(18)32)13-15-30(6)23-17-27(3,25(33)34-7)11-10-26(23,2)12-14-29(22,30)5/h8-9,16,23,31-32H,1,10-15,17H2,2-7H3/t23?,26-,27-,28+,29-,30+/m1/s1	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	93	n/a	n/a	n/a	n/a	n/a	37
University of California Irvine					Assay Description Purified recombinant rat MGL was prepared and enzyme activity was assayed.				Chem Biol 16: 1045-52 (2009) Article DOI: 10.1016/j.chembiol.2009.09.012 BindingDB Entry DOI: 10.7270/Q2HH6HJ3
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM280586 (US10030020, Example 131) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2ccc(Cl)c(c2)N2CCOCC2)CC1)C(F)(F)F Show InChI InChI=1S/C23H28ClF6N3O3/c24-17-3-2-16(14-18(17)31-10-12-35-13-11-31)15-33-7-1-4-21(33)5-8-32(9-6-21)20(34)36-19(22(25,26)27)23(28,29)30/h2-3,14,19H,1,4-13,15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018)
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM280587 (US10030020, Example 132) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2ccc(Cl)c(c2)N2CCCC2)CC1)C(F)(F)F Show InChI InChI=1S/C23H28ClF6N3O2/c24-17-5-4-16(14-18(17)31-9-1-2-10-31)15-33-11-3-6-21(33)7-12-32(13-8-21)20(34)35-19(22(25,26)27)23(28,29)30/h4-5,14,19H,1-3,6-13,15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018)
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM280588 (US10030020, Example 133) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2ccc(c(c2)N2CCOCC2)C(F)(F)F)CC1)C(F)(F)F Show InChI InChI=1S/C24H28F9N3O3/c25-22(26,27)17-3-2-16(14-18(17)34-10-12-38-13-11-34)15-36-7-1-4-21(36)5-8-35(9-6-21)20(37)39-19(23(28,29)30)24(31,32)33/h2-3,14,19H,1,4-13,15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018)
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM280589 (US10030020, Example 134) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2ccc(c(c2)N2CCCC2)C(F)(F)F)CC1)C(F)(F)F Show InChI InChI=1S/C24H28F9N3O2/c25-22(26,27)17-5-4-16(14-18(17)34-9-1-2-10-34)15-36-11-3-6-21(36)7-12-35(13-8-21)20(37)38-19(23(28,29)30)24(31,32)33/h4-5,14,19H,1-3,6-13,15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018)
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM280590 (US10030020, Example 135) Show SMILES Cc1cc(CN2CCC3(C2)CCN(CC3)C(=O)OC(C(F)(F)F)C(F)(F)F)ccc1Cl Show InChI InChI=1S/C20H23ClF6N2O2/c1-13-10-14(2-3-15(13)21)11-28-7-4-18(12-28)5-8-29(9-6-18)17(30)31-16(19(22,23)24)20(25,26)27/h2-3,10,16H,4-9,11-12H2,1H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018)
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM280595 (US10030020, Example 140) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCN(Cc3ccc(N4CCOCC4)c(c3)C(F)(F)F)C2)CC1)C(F)(F)F Show InChI InChI=1S/C24H28F9N3O3/c25-22(26,27)17-13-16(1-2-18(17)35-9-11-38-12-10-35)14-34-6-3-21(15-34)4-7-36(8-5-21)20(37)39-19(23(28,29)30)24(31,32)33/h1-2,13,19H,3-12,14-15H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018)
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM280506 (US10030020, Example 51) Show SMILES CC1(C)CC2(CN1Cc1ccc(cc1N1CCOCC1)C(F)(F)F)CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C26H32F9N3O3/c1-22(2)15-23(5-7-37(8-6-23)21(39)41-20(25(30,31)32)26(33,34)35)16-38(22)14-17-3-4-18(24(27,28)29)13-19(17)36-9-11-40-12-10-36/h3-4,13,20H,5-12,14-16H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018)
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM280507 (US10030020, Example 52) Show SMILES CC1(C)CC2(CN1Cc1ccc(cc1N1CCC3(C1)CCOCC3)C(F)(F)F)CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C30H38F9N3O3/c1-25(2)17-27(6-10-40(11-7-27)24(43)45-23(29(34,35)36)30(37,38)39)19-42(25)16-20-3-4-21(28(31,32)33)15-22(20)41-12-5-26(18-41)8-13-44-14-9-26/h3-4,15,23H,5-14,16-19H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018)
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM280509 (US10030020, Example 54) Show SMILES CC1(C)CC2(CN1Cc1cccc(Cl)c1N1CCOCC1)CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C25H32ClF6N3O3/c1-22(2)15-23(6-8-34(9-7-23)21(36)38-20(24(27,28)29)25(30,31)32)16-35(22)14-17-4-3-5-18(26)19(17)33-10-12-37-13-11-33/h3-5,20H,6-16H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018)
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM280510 (US10030020, Example 55) Show SMILES CC1(C)CC2(CN1Cc1ccc(cc1N1CC3COCC3C1)C(F)(F)F)CCN(CC2)C(=O)OC(C(F)(F)F)C(F)(F)F Show InChI InChI=1S/C28H34F9N3O3/c1-24(2)15-25(5-7-38(8-6-25)23(41)43-22(27(32,33)34)28(35,36)37)16-40(24)12-17-3-4-20(26(29,30)31)9-21(17)39-10-18-13-42-14-19(18)11-39/h3-4,9,18-19,22H,5-8,10-16H2,1-2H3	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018)
					More data for this Ligand-Target Pair
Monoglyceride Lipase (MGL) (Mus musculus (mouse))	BDBM280515 (US10030020, Example 60) Show SMILES FC(F)(F)C(OC(=O)N1CCC2(CCCN2Cc2ccccc2Cl)CC1)C(F)(F)F Show InChI InChI=1S/C19H21ClF6N2O2/c20-14-5-2-1-4-13(14)12-28-9-3-6-17(28)7-10-27(11-8-17)16(29)30-15(18(21,22)23)19(24,25)26/h1-2,4-5,15H,3,6-12H2	Reactome pathway KEGG UniProtKB/SwissProt GoogleScholar AffyNet	UniChem		n/a	n/a	<100	n/a	n/a	n/a	n/a	n/a	n/a
ABIDE THERAPEUTICS, INC. US Patent					Assay Description Proteomes (mouse brain membrane fraction or cell lysates) (50 μL, 1.0 mg/mL total protein concentration) were preincubated with varying concentr...				US Patent US10030020 (2018)
					More data for this Ligand-Target Pair

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