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Compile Data Set for Download or QSAR

Found 3222 hits Enz. Inhib. hit(s) with Target = 'B-RAF V600E'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
B-RAF V600E


(Homo sapiens (Human))
BDBM333638
PNG
(1-(3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(no4)C(C)(C)F)c3)c2cc1OC
Show InChI InChI=1S/C23H22FN5O4S/c1-23(2,24)19-11-20(33-29-19)28-22(30)27-13-6-5-7-14(8-13)34-21-15-9-17(31-3)18(32-4)10-16(15)25-12-26-21/h5-12H,1-4H3,(H2,27,28,30)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333642
PNG
(1-[5-(1,3- difluoro-2- methylpropan- 2- yl)isoxazo...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(CF)CF)c3)c2cc1OC
Show InChI InChI=1S/C24H23F2N5O4S/c1-24(11-25,12-26)20-10-21(31-35-20)30-23(32)29-14-5-4-6-15(7-14)36-22-16-8-18(33-2)19(34-3)9-17(16)27-13-28-22/h4-10,13H,11-12H2,1-3H3,(H2,29,30,31,32)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333644
PNG
(1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(nn4C)C(F)(F)F)c3)c2cc1OC
Show InChI InChI=1S/C22H19F3N6O3S/c1-31-19(10-18(30-31)22(23,24)25)29-21(32)28-12-5-4-6-13(7-12)35-20-14-8-16(33-2)17(34-3)9-15(14)26-11-27-20/h4-11H,1-3H3,(H2,28,29,32)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333645
PNG
(1-[3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)NC4=CC(=[N](C)N4)C(F)(F)F)c3)c2cc1OC
Show InChI InChI=1S/C22H20F3N6O3S/c1-31-18(22(23,24)25)10-19(30-31)29-21(32)28-12-5-4-6-13(7-12)35-20-14-8-16(33-2)17(34-3)9-15(14)26-11-27-20/h4-11,30H,1-3H3,(H2,28,29,32)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333652
PNG
(1-(5- cyclopentyl- isoxazol- 3-yl)- 3-(3-(6,7- dim...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(on4)C4CCCC4)c3)c2cc1OC
Show InChI InChI=1S/C25H25N5O4S/c1-32-21-11-18-19(12-22(21)33-2)26-14-27-24(18)35-17-9-5-8-16(10-17)28-25(31)29-23-13-20(34-30-23)15-6-3-4-7-15/h5,8-15H,3-4,6-7H2,1-2H3,(H2,28,29,30,31)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333653
PNG
(1-(3-tert- butylisoxazol- 5-yl)-3-(3- (6-methoxy- ...)
Show SMILES COCCOc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(no4)C(C)(C)C)c3)c2cc1OC
Show InChI InChI=1S/C26H29N5O6/c1-26(2,3)22-14-23(37-31-22)30-25(32)29-16-7-6-8-17(11-16)36-24-18-12-20(34-5)21(35-10-9-33-4)13-19(18)27-15-28-24/h6-8,11-15H,9-10H2,1-5H3,(H2,29,30,32)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333510
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-{3- [6-methoxy- ...)
Show SMILES COCCOc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)c2cc1OC
Show InChI InChI=1S/C26H29N5O5S/c1-26(2,3)22-14-23(31-36-22)30-25(32)29-16-7-6-8-17(11-16)37-24-18-12-20(34-5)21(35-10-9-33-4)13-19(18)27-15-28-24/h6-8,11-15H,9-10H2,1-5H3,(H2,29,30,31,32)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333511
PNG
(1-{3-[6,7- bis(2- methoxyethoxy) quinazolin-4- ylt...)
Show SMILES COCCOc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)c2cc1OCCOC
Show InChI InChI=1S/C28H33N5O6S/c1-28(2,3)24-16-25(33-39-24)32-27(34)31-18-7-6-8-19(13-18)40-26-20-14-22(37-11-9-35-4)23(38-12-10-36-5)15-21(20)29-17-30-26/h6-8,13-17H,9-12H2,1-5H3,(H2,31,32,33,34)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333513
PNG
(1-(5-tert- Butylisoxazol- 3-yl)-3-{3- [7-methoxy- ...)
Show SMILES COc1cc(OC2CCOCC2)c2c(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)ncnc2c1
Show InChI InChI=1S/C28H31N5O5S/c1-28(2,3)23-15-24(33-38-23)32-27(34)31-17-6-5-7-20(12-17)39-26-25-21(29-16-30-26)13-19(35-4)14-22(25)37-18-8-10-36-11-9-18/h5-7,12-16,18H,8-11H2,1-4H3,(H2,31,32,33,34)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333514
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-ethoxy-7-...)
Show SMILES CCOc1cc2c(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)ncnc2cc1OC
Show InChI InChI=1S/C25H27N5O4S/c1-6-33-20-11-17-18(12-19(20)32-5)26-14-27-23(17)35-16-9-7-8-15(10-16)28-24(31)29-22-13-21(34-30-22)25(2,3)4/h7-14H,6H2,1-5H3,(H2,28,29,30,31)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333516
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-methoxy- ...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)c2cc1OCCCN1CCCCC1
Show InChI InChI=1S/C31H38N6O4S/c1-31(2,3)27-19-28(36-41-27)35-30(38)34-21-10-8-11-22(16-21)42-29-23-17-26(25(39-4)18-24(23)32-20-33-29)40-15-9-14-37-12-6-5-7-13-37/h8,10-11,16-20H,5-7,9,12-15H2,1-4H3,(H2,34,35,36,38)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333517
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-(3-(4- (h...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)c2cc1OCCCN1CCC(CO)CC1
Show InChI InChI=1S/C32H40N6O5S/c1-32(2,3)28-18-29(37-43-28)36-31(40)35-22-7-5-8-23(15-22)44-30-24-16-27(26(41-4)17-25(24)33-20-34-30)42-14-6-11-38-12-9-21(19-39)10-13-38/h5,7-8,15-18,20-21,39H,6,9-14,19H2,1-4H3,(H2,35,36,37,40)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333518
PNG
(1-(5-tert- Butylisoxazol- 3-yl)-3-(3- (7-methoxy- ...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)c2cc1OCCCN1CCN(C)CC1
Show InChI InChI=1S/C31H39N7O4S/c1-31(2,3)27-19-28(36-42-27)35-30(39)34-21-8-6-9-22(16-21)43-29-23-17-26(25(40-5)18-24(23)32-20-33-29)41-15-7-10-38-13-11-37(4)12-14-38/h6,8-9,16-20H,7,10-15H2,1-5H3,(H2,34,35,36,39)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333519
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-methoixy-...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)c2cc1OCCCN1CCN(CC1)S(C)(=O)=O
Show InChI InChI=1S/C31H39N7O6S2/c1-31(2,3)27-19-28(36-44-27)35-30(39)34-21-8-6-9-22(16-21)45-29-23-17-26(25(42-4)18-24(23)32-20-33-29)43-15-7-10-37-11-13-38(14-12-37)46(5,40)41/h6,8-9,16-20H,7,10-15H2,1-5H3,(H2,34,35,36,39)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333520
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-(3-(4-(2-...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)c2cc1OCCCN1CCN(CCO)CC1
Show InChI InChI=1S/C32H41N7O5S/c1-32(2,3)28-20-29(37-44-28)36-31(41)35-22-7-5-8-23(17-22)45-30-24-18-27(26(42-4)19-25(24)33-21-34-30)43-16-6-9-38-10-12-39(13-11-38)14-15-40/h5,7-8,17-21,40H,6,9-16H2,1-4H3,(H2,35,36,37,41)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333521
PNG
(1-(5-tert- butyl- isoxazol-3- yl)-3-(3-{6- [3-(1,1...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)c2cc1OCCCN1CCS(=O)(=O)CC1
Show InChI InChI=1S/C30H36N6O6S2/c1-30(2,3)26-18-27(35-42-26)34-29(37)33-20-7-5-8-21(15-20)43-28-22-16-25(24(40-4)17-23(22)31-19-32-28)41-12-6-9-36-10-13-44(38,39)14-11-36/h5,7-8,15-19H,6,9-14H2,1-4H3,(H2,33,34,35,37)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333522
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-methoxy- ...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)c2cc1OCCCN1CCOCC1
Show InChI InChI=1S/C30H36N6O5S/c1-30(2,3)26-18-27(35-41-26)34-29(37)33-20-7-5-8-21(15-20)42-28-22-16-25(24(38-4)17-23(22)31-19-32-28)40-12-6-9-36-10-13-39-14-11-36/h5,7-8,15-19H,6,9-14H2,1-4H3,(H2,33,34,35,37)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333502
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-methoxy- ...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)c2cc1OCCCS(C)(=O)=O
Show InChI InChI=1S/C27H31N5O6S2/c1-27(2,3)23-15-24(32-38-23)31-26(33)30-17-8-6-9-18(12-17)39-25-19-13-22(37-10-7-11-40(5,34)35)21(36-4)14-20(19)28-16-29-25/h6,8-9,12-16H,7,10-11H2,1-5H3,(H2,30,31,32,33)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333524
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-methoxy- ...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)c2cc1OCCN1CCCCC1
Show InChI InChI=1S/C30H36N6O4S/c1-30(2,3)26-18-27(35-40-26)34-29(37)33-20-9-8-10-21(15-20)41-28-22-16-25(24(38-4)17-23(22)31-19-32-28)39-14-13-36-11-6-5-7-12-36/h8-10,15-19H,5-7,11-14H2,1-4H3,(H2,33,34,35,37)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333525
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-(2-(4- (h...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)c2cc1OCCN1CCC(CO)CC1
Show InChI InChI=1S/C31H38N6O5S/c1-31(2,3)27-17-28(36-42-27)35-30(39)34-21-6-5-7-22(14-21)43-29-23-15-26(25(40-4)16-24(23)32-19-33-29)41-13-12-37-10-8-20(18-38)9-11-37/h5-7,14-17,19-20,38H,8-13,18H2,1-4H3,(H2,34,35,36,39)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333713
PNG
(1-(3-(7- hydroxy-6- methoxy- quinazolin- 4- yloxy)...)
Show SMILES COc1cc2c(Oc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C(F)(F)F)c3)ncnc2cc1O
Show InChI InChI=1S/C23H20F3N5O5/c1-22(2,23(24,25)26)18-10-19(31-36-18)30-21(33)29-12-5-4-6-13(7-12)35-20-14-8-17(34-3)16(32)9-15(14)27-11-28-20/h4-11,32H,1-3H3,(H2,29,30,31,33)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333714
PNG
(1-(3-(6- hydroxy-7- methoxy- quinazolin- 4- yloxy)...)
Show SMILES COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C(F)(F)F)c3)c2cc1O
Show InChI InChI=1S/C23H20F3N5O5/c1-22(2,23(24,25)26)18-10-19(31-36-18)30-21(33)29-12-5-4-6-13(7-12)35-20-14-8-16(32)17(34-3)9-15(14)27-11-28-20/h4-11,32H,1-3H3,(H2,29,30,31,33)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333715
PNG
(1-(3-(6,7- dimethoxy- quinazolin- 4- yloxy)-2- flu...)
Show SMILES COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C(F)(F)F)c3F)c2cc1OC
Show InChI InChI=1S/C24H21F4N5O5/c1-23(2,24(26,27)28)18-10-19(33-38-18)32-22(34)31-13-6-5-7-15(20(13)25)37-21-12-8-16(35-3)17(36-4)9-14(12)29-11-30-21/h5-11H,1-4H3,(H2,31,32,33,34)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333716
PNG
(1-(3-(6,7- dimethoxy- quinazolin- 4- yloxy)-4- flu...)
Show SMILES COc1cc2ncnc(Oc3cc(NC(=O)Nc4cc(on4)C(C)(C)C(F)(F)F)ccc3F)c2cc1OC
Show InChI InChI=1S/C24H21F4N5O5/c1-23(2,24(26,27)28)19-10-20(33-38-19)32-22(34)31-12-5-6-14(25)16(7-12)37-21-13-8-17(35-3)18(36-4)9-15(13)29-11-30-21/h5-11H,1-4H3,(H2,31,32,33,34)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333717
PNG
(1-(3-(6,7- dimethoxy- quinazolin- 4- yloxy)phenyl)...)
Show SMILES COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(no4)C(C)(C)C(F)(F)F)c3)c2cc1OC
Show InChI InChI=1S/C24H22F3N5O5/c1-23(2,24(25,26)27)19-11-20(37-32-19)31-22(33)30-13-6-5-7-14(8-13)36-21-15-9-17(34-3)18(35-4)10-16(15)28-12-29-21/h5-12H,1-4H3,(H2,30,31,33)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333718
PNG
(1-(3-(6,7- dimethoxy- quinazolin- 4- ylthio)phenyl...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(no4)C(C)(C)C(F)(F)F)c3)c2cc1OC
Show InChI InChI=1S/C24H22F3N5O4S/c1-23(2,24(25,26)27)19-11-20(36-32-19)31-22(33)30-13-6-5-7-14(8-13)37-21-15-9-17(34-3)18(35-4)10-16(15)28-12-29-21/h5-12H,1-4H3,(H2,30,31,33)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333719
PNG
(1-(5-(6,7- dimethoxy- quinazolin- 4-yloxy)- 2,4-di...)
Show SMILES COc1cc2ncnc(Oc3cc(NC(=O)Nc4cc(no4)C(C)(C)F)c(F)cc3F)c2cc1OC
Show InChI InChI=1S/C23H20F3N5O5/c1-23(2,26)19-9-20(36-31-19)30-22(32)29-15-8-16(13(25)6-12(15)24)35-21-11-5-17(33-3)18(34-4)7-14(11)27-10-28-21/h5-10H,1-4H3,(H2,29,30,32)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333720
PNG
(1-(5-tert- butylisoxazol- 3-yl)- 3-(5- (6,7- dimet...)
Show SMILES COc1cc2ncnc(Oc3cc(NC(=O)Nc4cc(on4)C(C)(C)C)c(F)cc3F)c2cc1OC
Show InChI InChI=1S/C24H23F2N5O5/c1-24(2,3)20-10-21(31-36-20)30-23(32)29-16-9-17(14(26)7-13(16)25)35-22-12-6-18(33-4)19(34-5)8-15(12)27-11-28-22/h6-11H,1-5H3,(H2,29,30,31,32)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333726
PNG
(1-(3-tert- butyl-1-p- tolyl-1H- pyrazol-5-yl)- 3-(...)
Show SMILES COCCOc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(nn4-c4ccc(C)cc4)C(C)(C)C)c3)c2cc1OC
Show InChI InChI=1S/C33H36N6O5/c1-21-10-12-23(13-11-21)39-30(19-29(38-39)33(2,3)4)37-32(40)36-22-8-7-9-24(16-22)44-31-25-17-27(42-6)28(43-15-14-41-5)18-26(25)34-20-35-31/h7-13,16-20H,14-15H2,1-6H3,(H2,36,37,40)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333728
PNG
(1-(3-(2-cyano- propan- 2- yl)phenyl)-3- (3-(6,7- d...)
Show SMILES COc1cc2ncnc(Oc3cccc(NC(=O)Nc4cccc(c4)C(C)(C)C#N)c3)c2cc1OC
Show InChI InChI=1S/C27H25N5O4/c1-27(2,15-28)17-7-5-8-18(11-17)31-26(33)32-19-9-6-10-20(12-19)36-25-21-13-23(34-3)24(35-4)14-22(21)29-16-30-25/h5-14,16H,1-4H3,(H2,31,32,33)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333526
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-methoxy- ...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)c2cc1OCCN1CCN(C)CC1
Show InChI InChI=1S/C30H37N7O4S/c1-30(2,3)26-18-27(35-41-26)34-29(38)33-20-7-6-8-21(15-20)42-28-22-16-25(24(39-5)17-23(22)31-19-32-28)40-14-13-37-11-9-36(4)10-12-37/h6-8,15-19H,9-14H2,1-5H3,(H2,33,34,35,38)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333527
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-(2-(4-(2-...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)c2cc1OCCN1CCN(CCO)CC1
Show InChI InChI=1S/C31H39N7O5S/c1-31(2,3)27-19-28(36-43-27)35-30(40)34-21-6-5-7-22(16-21)44-29-23-17-26(25(41-4)18-24(23)32-20-33-29)42-15-13-38-10-8-37(9-11-38)12-14-39/h5-7,16-20,39H,8-15H2,1-4H3,(H2,34,35,36,40)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333528
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-methoxy- ...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)c2cc1OCCN1CCN(CC1)S(C)(=O)=O
Show InChI InChI=1S/C30H37N7O6S2/c1-30(2,3)26-18-27(35-43-26)34-29(38)33-20-7-6-8-21(15-20)44-28-22-16-25(24(41-4)17-23(22)31-19-32-28)42-14-13-36-9-11-37(12-10-36)45(5,39)40/h6-8,15-19H,9-14H2,1-5H3,(H2,33,34,35,38)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333529
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-methoxy- ...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)c2cc1OCCN1CCOCC1
Show InChI InChI=1S/C29H34N6O5S/c1-29(2,3)25-17-26(34-40-25)33-28(36)32-19-6-5-7-20(14-19)41-27-21-15-24(23(37-4)16-22(21)30-18-31-27)39-13-10-35-8-11-38-12-9-35/h5-7,14-18H,8-13H2,1-4H3,(H2,32,33,34,36)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333530
PNG
(1-(5-tert- butyl- isoxazol-3- yl)-3-(3-{6- [2-1,1-...)
Show SMILES COc1cc2ncnc(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)c2cc1OCCN1CCS(=O)(=O)CC1
Show InChI InChI=1S/C29H34N6O6S2/c1-29(2,3)25-17-26(34-41-25)33-28(36)32-19-6-5-7-20(14-19)42-27-21-15-24(23(39-4)16-22(21)30-18-31-27)40-11-8-35-9-12-43(37,38)13-10-35/h5-7,14-18H,8-13H2,1-4H3,(H2,32,33,34,36)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333531
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-methoxy- ...)
Show SMILES COc1cc2c(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)ncnc2cc1OCCCN1CCOCC1
Show InChI InChI=1S/C30H36N6O5S/c1-30(2,3)26-18-27(35-41-26)34-29(37)33-20-7-5-8-21(15-20)42-28-22-16-24(38-4)25(17-23(22)31-19-32-28)40-12-6-9-36-10-13-39-14-11-36/h5,7-8,15-19H,6,9-14H2,1-4H3,(H2,33,34,35,37)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333532
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-methoxy- ...)
Show SMILES COc1cc2c(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)ncnc2cc1OCCCN1CCN(C)CC1
Show InChI InChI=1S/C31H39N7O4S/c1-31(2,3)27-19-28(36-42-27)35-30(39)34-21-8-6-9-22(16-21)43-29-23-17-25(40-5)26(18-24(23)32-20-33-29)41-15-7-10-38-13-11-37(4)12-14-38/h6,8-9,16-20H,7,10-15H2,1-5H3,(H2,34,35,36,39)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333533
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-(3-(4- (h...)
Show SMILES COc1cc2c(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)ncnc2cc1OCCCN1CCC(CO)CC1
Show InChI InChI=1S/C32H40N6O5S/c1-32(2,3)28-18-29(37-43-28)36-31(40)35-22-7-5-8-23(15-22)44-30-24-16-26(41-4)27(17-25(24)33-20-34-30)42-14-6-11-38-12-9-21(19-39)10-13-38/h5,7-8,15-18,20-21,39H,6,9-14,19H2,1-4H3,(H2,35,36,37,40)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333534
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-(3-(4-(2-...)
Show SMILES COc1cc2c(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)ncnc2cc1OCCCN1CCN(CCO)CC1
Show InChI InChI=1S/C32H41N7O5S/c1-32(2,3)28-20-29(37-44-28)36-31(41)35-22-7-5-8-23(17-22)45-30-24-18-26(42-4)27(19-25(24)33-21-34-30)43-16-6-9-38-10-12-39(13-11-38)14-15-40/h5,7-8,17-21,40H,6,9-16H2,1-4H3,(H2,35,36,37,41)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333535
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-methoxy- ...)
Show SMILES COc1cc2c(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)ncnc2cc1OCCCN1CCCCC1
Show InChI InChI=1S/C31H38N6O4S/c1-31(2,3)27-19-28(36-41-27)35-30(38)34-21-10-8-11-22(16-21)42-29-23-17-25(39-4)26(18-24(23)32-20-33-29)40-15-9-14-37-12-6-5-7-13-37/h8,10-11,16-20H,5-7,9,12-15H2,1-4H3,(H2,34,35,36,38)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333536
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-methoxy- ...)
Show SMILES COc1cc2c(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)ncnc2cc1OCCCN1CCN(CC1)S(C)(=O)=O
Show InChI InChI=1S/C31H39N7O6S2/c1-31(2,3)27-19-28(36-44-27)35-30(39)34-21-8-6-9-22(16-21)45-29-23-17-25(42-4)26(18-24(23)32-20-33-29)43-15-7-10-37-11-13-38(14-12-37)46(5,40)41/h6,8-9,16-20H,7,10-15H2,1-5H3,(H2,34,35,36,39)
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AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333537
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-methoxy- ...)
Show SMILES COc1cc2c(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)ncnc2cc1OCCN1CCOCC1
Show InChI InChI=1S/C29H34N6O5S/c1-29(2,3)25-17-26(34-40-25)33-28(36)32-19-6-5-7-20(14-19)41-27-21-15-23(37-4)24(16-22(21)30-18-31-27)39-13-10-35-8-11-38-12-9-35/h5-7,14-18H,8-13H2,1-4H3,(H2,32,33,34,36)
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n/an/an/a<250n/an/an/an/an/a



AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333538
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-methoxy- ...)
Show SMILES COc1cc2c(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)ncnc2cc1OCCN1CCCCC1
Show InChI InChI=1S/C30H36N6O4S/c1-30(2,3)26-18-27(35-40-26)34-29(37)33-20-9-8-10-21(15-20)41-28-22-16-24(38-4)25(17-23(22)31-19-32-28)39-14-13-36-11-6-5-7-12-36/h8-10,15-19H,5-7,11-14H2,1-4H3,(H2,33,34,35,37)
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n/an/an/a<250n/an/an/an/an/a



AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333539
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-methoxy- ...)
Show SMILES COc1cc2c(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)ncnc2cc1OCCN1CCN(CC1)S(C)(=O)=O
Show InChI InChI=1S/C30H37N7O6S2/c1-30(2,3)26-18-27(35-43-26)34-29(38)33-20-7-6-8-21(15-20)44-28-22-16-24(41-4)25(17-23(22)31-19-32-28)42-14-13-36-9-11-37(12-10-36)45(5,39)40/h6-8,15-19H,9-14H2,1-5H3,(H2,33,34,35,38)
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n/an/an/a<250n/an/an/an/an/a



AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333540
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (6-methoxy- ...)
Show SMILES COc1cc2c(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)ncnc2cc1OCCN1CCN(C)CC1
Show InChI InChI=1S/C30H37N7O4S/c1-30(2,3)26-18-27(35-41-26)34-29(38)33-20-7-6-8-21(15-20)42-28-22-16-24(39-5)25(17-23(22)31-19-32-28)40-14-13-37-11-9-36(4)10-12-37/h6-8,15-19H,9-14H2,1-5H3,(H2,33,34,35,38)
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n/an/an/a<250n/an/an/an/an/a



AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333541
PNG
(1-(5-tert- butylisoxazol- 3-yl)-3-(3- (7-(2-(4-(2-...)
Show SMILES COc1cc2c(Sc3cccc(NC(=O)Nc4cc(on4)C(C)(C)C)c3)ncnc2cc1OCCN1CCC(CCO)CC1
Show InChI InChI=1S/C32H40N6O5S/c1-32(2,3)28-19-29(37-43-28)36-31(40)35-22-6-5-7-23(16-22)44-30-24-17-26(41-4)27(18-25(24)33-20-34-30)42-15-13-38-11-8-21(9-12-38)10-14-39/h5-7,16-21,39H,8-15H2,1-4H3,(H2,35,36,37,40)
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n/an/an/a<250n/an/an/an/an/a



AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333658
PNG
(1-{3-[6- methoxy-7- (2- methoxyethoxy) quinazolin-...)
Show SMILES COCCOc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(n(C)n4)C(F)(F)F)c3)c2cc1OC
Show InChI InChI=1S/C24H23F3N6O5/c1-33-20(24(25,26)27)12-21(32-33)31-23(34)30-14-5-4-6-15(9-14)38-22-16-10-18(36-3)19(37-8-7-35-2)11-17(16)28-13-29-22/h4-6,9-13H,7-8H2,1-3H3,(H2,30,31,32,34)
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n/an/an/a<250n/an/an/an/an/a



AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333663
PNG
(1-[5-(1,3- difluoro-2- methylpropan-2- yl)isoxazol...)
Show SMILES COCCOc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(on4)C(C)(CF)CF)c3)c2cc1OC
Show InChI InChI=1S/C26H27F2N5O6/c1-26(13-27,14-28)22-12-23(33-39-22)32-25(34)31-16-5-4-6-17(9-16)38-24-18-10-20(36-3)21(37-8-7-35-2)11-19(18)29-15-30-24/h4-6,9-12,15H,7-8,13-14H2,1-3H3,(H2,31,32,33,34)
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n/an/an/a<250n/an/an/an/an/a



AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333664
PNG
(1-(3- cyclopropyl- isoxazol- 5- yl)-3-(3-(6- metho...)
Show SMILES COCCOc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(no4)C4CC4)c3)c2cc1OC
Show InChI InChI=1S/C25H25N5O6/c1-32-8-9-34-22-12-20-18(11-21(22)33-2)24(27-14-26-20)35-17-5-3-4-16(10-17)28-25(31)29-23-13-19(30-36-23)15-6-7-15/h3-5,10-15H,6-9H2,1-2H3,(H2,28,29,31)
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n/an/an/a<250n/an/an/an/an/a



AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
B-RAF V600E


(Homo sapiens (Human))
BDBM333665
PNG
(1-(3- isopropylisoxazol- 5-yl)- 3-(3-(6-methoxy- 7...)
Show SMILES COCCOc1cc2ncnc(Oc3cccc(NC(=O)Nc4cc(no4)C(C)C)c3)c2cc1OC
Show InChI InChI=1S/C25H27N5O6/c1-15(2)19-13-23(36-30-19)29-25(31)28-16-6-5-7-17(10-16)35-24-18-11-21(33-4)22(34-9-8-32-3)12-20(18)26-14-27-24/h5-7,10-15H,8-9H2,1-4H3,(H2,28,29,31)
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n/an/an/a<250n/an/an/an/an/a



AMBIT BIOSCIENCES CORPORATION

US Patent


Assay Description
Competition binding assays used herein were developed, validated and performed as described in Fabian et al., Nature Biotechnology 2005, 23, 329-336....


US Patent US9730937 (2017)

More data for this
Ligand-Target Pair
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