TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKd: 1.60nMAssay Description:Antagonist activity at human CCR5 expressed in HEK 293 Glosensor cells assessed as reduction in RANTES-induced intracellular calcium levels preincuba...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKd: 3.10nMAssay Description:Activation of CCR5 in human PBMC cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKd: 10nMAssay Description:Antagonist activity at human CCR5 expressed in HEK 293 Glosensor cells assessed as reduction in RANTES-induced intracellular calcium levels preincuba...More data for this Ligand-Target Pair
Affinity DataKd: 11nMAssay Description:Binding affinity to CCR5 in NY1DD transgenic mouse brain membraneMore data for this Ligand-Target Pair
Affinity DataKd: 21nMAssay Description:Binding affinity to CCR5 in C57BL/6J mouse brain membraneMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKd: 24nMAssay Description:Binding affinity to CCR5 in T-cell (unknown origin)More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKd: 25nMAssay Description:Binding affinity to CCR5More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKd: 316nMAssay Description:Antagonist activity at human CCR5 expressed in HEK 293 Glosensor cells assessed as reduction in RANTES-induced intracellular calcium levels preincuba...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKd: 8.20E+3nMAssay Description:Binding affinity to C-terminus C9-tagged immobilized CCR5 by SPR analysisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKd: 1.00E+4nMAssay Description:Binding affinity to C-terminus C9-tagged immobilized CCR5 by SPR analysisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKd: 1.08E+4nMAssay Description:Binding affinity to C-terminus C9-tagged immobilized CCR5 after 1 min by SPR assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKd: 1.75E+4nMAssay Description:Binding affinity to C-terminus C9-tagged immobilized CCR5 by SPR analysisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKd: 1.84E+4nMAssay Description:Binding affinity to C-terminus C9-tagged immobilized CCR5 by SPR analysisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKd: 2.26E+4nMAssay Description:Binding affinity to C-terminus C9-tagged immobilized CCR5 by SPR analysisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKd: 2.75E+4nMAssay Description:Binding affinity to C-terminus C9-tagged immobilized CCR5 by SPR analysisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKd: 2.86E+4nMAssay Description:Binding affinity to C-terminus C9-tagged immobilized CCR5 after 1 min by SPR assayMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKd: 4.90E+4nMAssay Description:Binding affinity to C-terminus C9-tagged immobilized CCR5 by SPR analysisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 0.100nMAssay Description:Inhibition of RANTES binding to the human C-C chemokine receptor type 5 (CCR5)More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Macaca fascicularis)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:Displacement of [125I]-MIP-1alpha from CCR5 in rhesus monkey Chem-1 cell membranes after 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Macaca fascicularis)
Virginia Commonwealth University
Curated by ChEMBL
Virginia Commonwealth University
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:Displacement of [125I]MIP-1alpha from CCR5 receptor in rhesus monkey membrane incubated for 120 mins by liquid scintillation counting analysisMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 0.240nMAssay Description:Afterwards, the pharmacological profile of bivalent ligand 1 at the chemokine receptor CCR5 was characterized similarly. The competitive radioligand ...More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Inhibition of [125I]RANTES binding to CCR5 receptor.More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 0.300nMAssay Description:Inhibition of RANTES binding to the human C-C chemokine receptor type 5 (CCR5)More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of [125I]RANTES binding to CCR5 receptor.More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 0.400nMAssay Description:Inhibition of RANTES binding to the human C-C chemokine receptor type 5 (CCR5)More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Inhibition of [125I]RANTES binding to CCR5 receptor.More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Inhibition of RANTES binding to the human C-C chemokine receptor type 5 (CCR5)More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to the CCR5 receptor expressed in membrane preparations from CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 0.700nMAssay Description:Inhibition of RANTES binding to the human C-C chemokine receptor type 5 (CCR5)More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of RANTES binding to C-C chemokine receptor type 5More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 1nMAssay Description:Inhibition of RANTES binding to the human C-C chemokine receptor type 5 (CCR5)More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Inhibition of RANTES binding to the human C-C chemokine receptor type 5 (CCR5)More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of RANTES binding to Chemokine receptor type 5 receptor from NIH 3T3 cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Antagonistic activity of the compound against C-C chemokine receptor type 5More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Inhibition of RANTES binding to C-C chemokine receptor type 5More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Inhibition of RANTES binding to C-C chemokine receptor type 5More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 1.10nMAssay Description:Inhibition of RANTES binding to the human C-C chemokine receptor type 5 (CCR5)More data for this Ligand-Target Pair
Affinity DataKi: 1.10nMAssay Description:Inhibition of RANTES binding to Chemokine receptor type 5 receptor from NIH 3T3 cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Inhibition of [125I]RANTES binding to CCR5 receptor.More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 1.20nMAssay Description:Inhibition of RANTES binding to the human C-C chemokine receptor type 5 (CCR5)More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of RANTES binding to the human C-C chemokine receptor type 5 (CCR5)More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 1.30nMAssay Description:Inhibition of [125I]RANTES binding to CCR5 receptor.More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Antagonistic activity of the compound against C-C chemokine receptor type 5More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 1.40nMAssay Description:Inhibitory activity of the compound against specific binding of [125I]-MIP-1 alpha to human CCR5 receptorMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 1.60nMAssay Description:Antagonistic activity of the compound against C-C chemokine receptor type 5More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Inhibition of RANTES binding to C-C chemokine receptor type 5More data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Ability to inhibit [125I]-labeled RANTES binding to the CCR5 receptor expressed in membrane preparations from CHO cellsMore data for this Ligand-Target Pair
TargetC-C chemokine receptor type 5(Homo sapiens (Human))
University Park Nottingham
Curated by ChEMBL
University Park Nottingham
Curated by ChEMBL
Affinity DataKi: 2nMAssay Description:Inhibition of RANTES binding to C-C chemokine receptor type 5More data for this Ligand-Target Pair