TargetHemagglutinin(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Third Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The Third Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataKd: 0.00700nMAssay Description:Binding affinity to Influenza A Puerto Rico/8/1934/H1N1 hemagglutin assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Third Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The Third Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataKd: 0.00700nMAssay Description:Binding affinity to Influenza A Puerto Rico/8/1934/H1N1 hemagglutin assessed as dissociation constant by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Third Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The Third Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataKd: 1.20nMAssay Description:Binding affinity to influenza A virus hemagglutin by surface plasmon resonance assayMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University
Curated by ChEMBL
Keio University
Curated by ChEMBL
Affinity DataKd: 7.80nMAssay Description:Binding affinity to Influenza A virus (A/Puerto Rico/8/34(H1N1)) hemagglutinin by phage ELISAMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University
Curated by ChEMBL
Keio University
Curated by ChEMBL
Affinity DataKd: 7.80nMAssay Description:Binding affinity to Influenza A virus (A/Puerto Rico/8/34(H1N1)) hemagglutinin by phage ELISAMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University
Curated by ChEMBL
Keio University
Curated by ChEMBL
Affinity DataKd: 11nMAssay Description:Binding affinity to Influenza A virus (A/Puerto Rico/8/34(H1N1)) hemagglutinin by phage ELISAMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Third Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The Third Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataKd: 16nMAssay Description:Binding affinity to hemagglutinin by SPR assayMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University
Curated by ChEMBL
Keio University
Curated by ChEMBL
Affinity DataKd: 19nMAssay Description:Binding affinity to Influenza A virus (A/Puerto Rico/8/34(H1N1)) hemagglutinin by phage ELISAMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University
Curated by ChEMBL
Keio University
Curated by ChEMBL
Affinity DataKd: 30nMAssay Description:Binding affinity to Influenza A virus (A/Puerto Rico/8/34(H1N1)) hemagglutinin by phage ELISAMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Third Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The Third Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataKd: 446nMAssay Description:Inhibition of CM5 chip immobilized Influenza A virus (A/Viet Nam/1203/2004(H5N1)) HA by SPR methodMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University
Curated by ChEMBL
Keio University
Curated by ChEMBL
Affinity DataKd: 2.63E+3nMAssay Description:Binding affinity to CM5 chip immobilized Influenza A virus (A/Michigan/45/2015) (H1N1)) hemagglutin assessed as dissociation constant by surface plas...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Third Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The Third Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataKd: 3.18E+3nMAssay Description:Binding affinity to recombinant influenza A hemagglutinin assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University
Curated by ChEMBL
Keio University
Curated by ChEMBL
Affinity DataKd: 4.50E+3nMAssay Description:Binding affinity to Influenza A virus (A/Puerto Rico/8/1934(H1N1)) Hemagglutinin at 1.5625 to 50 uM by SPR assayMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University
Curated by ChEMBL
Keio University
Curated by ChEMBL
Affinity DataKd: 6.30E+3nMAssay Description:Binding affinity to Influenza A virus (A/Puerto Rico/8/1934(H1N1)) Hemagglutinin at 1.5625 to 50 uM by SPR assayMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University
Curated by ChEMBL
Keio University
Curated by ChEMBL
Affinity DataKd: 6.90E+3nMAssay Description:Binding affinity to Influenza A virus (A/California/04/2009(H1N1)) Hemagglutinin at 1.5625 to 50 uM by SPR assayMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Third Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The Third Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataKd: 1.09E+4nMAssay Description:Binding affinity to recombinant influenza A hemagglutinin assessed as dissociation constant by SPR assayMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University
Curated by ChEMBL
Keio University
Curated by ChEMBL
Affinity DataKd: 1.11E+4nMAssay Description:Binding affinity to Influenza A virus (A/Puerto Rico/8/1934(H1N1)) Hemagglutinin at 1.5625 to 50 uM by SPR assayMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University
Curated by ChEMBL
Keio University
Curated by ChEMBL
Affinity DataKd: 1.56E+4nMAssay Description:Binding affinity to recombinant Influenza A virus (A/California/04/2009 (H1N1)) hemagglutinin by SPR assayMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University
Curated by ChEMBL
Keio University
Curated by ChEMBL
Affinity DataKd: 1.56E+4nMAssay Description:Binding affinity to recombinant Influenza A virus (A/California/04/2009 (H1N1)) hemagglutinin by SPR assayMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Third Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The Third Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataKd: 3.20E+4nMAssay Description:Binding affinity to influenza A virus A/WSN/33 (H1N1) Hemagglutinin by surface Plasmon resonance assayMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University
Curated by ChEMBL
Keio University
Curated by ChEMBL
Affinity DataKd: 3.60E+4nMAssay Description:Binding affinity to recombinant Influenza A virus (A/California/04/2009 (H1N1)) hemagglutinin by SPR assayMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University
Curated by ChEMBL
Keio University
Curated by ChEMBL
Affinity DataKd: 3.60E+4nMAssay Description:Binding affinity to recombinant Influenza A virus (A/California/04/2009 (H1N1)) hemagglutinin by SPR assayMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University
Curated by ChEMBL
Keio University
Curated by ChEMBL
Affinity DataKd: 4.65E+4nMAssay Description:Binding affinity to recombinant Influenza A virus (A/California/04/2009 (H1N1)) hemagglutinin by SPR assayMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University
Curated by ChEMBL
Keio University
Curated by ChEMBL
Affinity DataKd: 4.65E+4nMAssay Description:Binding affinity to recombinant Influenza A virus (A/California/04/2009 (H1N1)) hemagglutinin by SPR assayMore data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Wilson-Smith/1933 H1N1...)
The Third Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
The Third Affiliated Hospital Of Guangzhou Medical University
Curated by ChEMBL
Affinity DataKd: 9.80E+4nMAssay Description:Binding affinity to influenza A virus A/WSN/33 (H1N1) Hemagglutinin by surface Plasmon resonance assayMore data for this Ligand-Target Pair
Affinity DataKi: 1nM ΔG°: -53.4kJ/mole IC50: 5nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+5nM ΔG°: >-23.7kJ/mole IC50: >1.00E+5nMpH: 6.5 T: 2°CAssay Description:A standard fluorimetric assay was used to measure influenza virus neuraminidase activity. The substrate 2 -(4-methylumbelliferyl)-alpha-D-acetylneura...More data for this Ligand-Target Pair
Affinity DataEC50: 1.22nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
Affinity DataEC50: 0.521nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
Affinity DataEC50: 0.680nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0110nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
Affinity DataEC50: 0.0790nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
Affinity DataEC50: 0.887nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
Affinity DataEC50: 0.274nMAssay Description:MDCK cells (Madin-Daby canine kidney cells) were seeded in a 384-well plate with 2000 cells per well and cultured at 37° C. under 5% CO2 condition ov...More data for this Ligand-Target Pair
TargetHemagglutinin(Influenza A virus (strain A/Puerto Rico/8/1934 H1N...)
Keio University
Curated by ChEMBL
Keio University
Curated by ChEMBL
Affinity DataIC50: 1.20E+4nMAssay Description:Inhibition of Influenza A virus (A/PR 8/34 (H1N1)) hemagglutinin transfected in human HeLa cells assessed as reduction in low pH-indued polykaryon fo...More data for this Ligand-Target Pair
Affinity DataEC50: 5.07E+3nMAssay Description:The ability of the tested compound to block influenza virus replication (PR8 and X31) in Calu-3 human bronchial epithelial cells was evaluated as des...More data for this Ligand-Target Pair
Affinity DataEC50: 7.70E+3nMAssay Description:The ability of the tested compound to block influenza virus replication (PR8 and X31) in Calu-3 human bronchial epithelial cells was evaluated as des...More data for this Ligand-Target Pair
Affinity DataEC50: 5.69E+3nMAssay Description:The ability of the tested compound to block influenza virus replication (PR8 and X31) in Calu-3 human bronchial epithelial cells was evaluated as des...More data for this Ligand-Target Pair
Affinity DataEC50: 27.3nMAssay Description:The ability of the tested compound to block influenza virus replication (PR8 and X31) in Calu-3 human bronchial epithelial cells was evaluated as des...More data for this Ligand-Target Pair
Affinity DataEC50: 20.9nMAssay Description:The ability of the tested compound to block influenza virus replication (PR8 and X31) in Calu-3 human bronchial epithelial cells was evaluated as des...More data for this Ligand-Target Pair
Affinity DataEC50: 1.56nMAssay Description:The ability of the tested compound to block influenza virus replication (PR8 and X31) in Calu-3 human bronchial epithelial cells was evaluated as des...More data for this Ligand-Target Pair
Affinity DataEC50: 9.33nMAssay Description:The ability of the tested compound to block influenza virus replication (PR8 and X31) in Calu-3 human bronchial epithelial cells was evaluated as des...More data for this Ligand-Target Pair
Affinity DataEC50: 2.28nMAssay Description:The ability of the tested compound to block influenza virus replication (PR8 and X31) in Calu-3 human bronchial epithelial cells was evaluated as des...More data for this Ligand-Target Pair
Affinity DataEC50: 34nMAssay Description:The ability of the tested compound to block influenza virus replication (PR8 and X31) in Calu-3 human bronchial epithelial cells was evaluated as des...More data for this Ligand-Target Pair
Affinity DataIC50: 7.38E+3nMAssay Description:The cytopathic effect (CPE) inhibition test is used for measuring the antiviral effect. Monolayer cells in 96-well plates are inoculated with 0.1 ml ...More data for this Ligand-Target Pair
Affinity DataIC50: 6.60E+3nMAssay Description:The cytopathic effect (CPE) inhibition test is used for measuring the antiviral effect. Monolayer cells in 96-well plates are inoculated with 0.1 ml ...More data for this Ligand-Target Pair
Affinity DataIC50: 9.60E+3nMAssay Description:The cytopathic effect (CPE) inhibition test is used for measuring the antiviral effect. Monolayer cells in 96-well plates are inoculated with 0.1 ml ...More data for this Ligand-Target Pair
Affinity DataIC50: 30nMAssay Description:The cytopathic effect (CPE) inhibition test is used for measuring the antiviral effect. Monolayer cells in 96-well plates are inoculated with 0.1 ml ...More data for this Ligand-Target Pair
Affinity DataIC50: 130nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair
Affinity DataIC50: 1nMAssay Description:The in vitro antiviral activity of the compounds was determined using a cell-based antiviral assay. In this assay, the cytopathic effect (CPE) in Mad...More data for this Ligand-Target Pair