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Compile Data Set for Download or QSAR

Found 511 hits Enz. Inhib. hit(s) with Target = 'Menin'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Menin/Histone-lysine N-methyltransferase MLL


(Homo sapiens (Human))
BDBM50489222
PNG
(CHEMBL2314822)
Show SMILES NC(=N)NCCC[C@H](NC(=O)COCCOCCOCCNC(=O)c1ccc2c(c1)C(=O)OC21c2ccc(O)cc2Oc2cc(O)ccc12)C(=O)N[C@@H](Cc1cc2ccccc2[nH]1)C(=O)N[C@H]1CCCCCCCCNC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC(=O)C2(CCC2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cc(F)cc(F)c2)NC1=O
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n/an/an/a 1.40n/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay


J Med Chem 56: 1113-23 (2013)

More data for this
Ligand-Target Pair
Menin


(Homo sapiens (Human))
BDBM50156122
PNG
(CHEMBL3781030)
Show SMILES Oc1cc2n(Cc3cn[nH]c3)c(cc2cc1CN1CCC(CC1)Nc1ncnc2sc(CC(F)(F)F)cc12)C#N
Show InChI InChI=1S/C27H25F3N8OS/c28-27(29,30)9-21-7-22-25(32-15-33-26(22)40-21)36-19-1-3-37(4-2-19)14-18-5-17-6-20(10-31)38(23(17)8-24(18)39)13-16-11-34-35-12-16/h5-8,11-12,15,19,39H,1-4,9,13-14H2,(H,34,35)(H,32,33,36)
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n/an/an/a 6.5n/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity to menin (unknown origin)


J Med Chem 59: 892-913 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01305
BindingDB Entry DOI: 10.7270/Q2M32XM7
More data for this
Ligand-Target Pair
Menin/Histone-lysine N-methyltransferase MLL


(Homo sapiens (Human))
BDBM50455873
PNG
(CHEMBL4216801)
Show SMILES Cc1c(CN2CCC(CC2)Nc2ncnc3sc(CC(F)(F)F)cc23)ccc2n(C[C@@H]3CNC(=O)CO3)c(cc12)C#N
Show InChI InChI=1S/C29H30F3N7O2S/c1-17-18(2-3-25-23(17)8-20(11-33)39(25)14-21-12-34-26(40)15-41-21)13-38-6-4-19(5-7-38)37-27-24-9-22(10-29(30,31)32)42-28(24)36-16-35-27/h2-3,8-9,16,19,21H,4-7,10,12-15H2,1H3,(H,34,40)(H,35,36,37)/t21-/m0/s1
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n/an/an/a 9n/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity to human C-terminal Avi-tagged menin expressed in Escherichia coli BL21 (DE3) cells by bio-layer interferometry


J Med Chem 61: 4832-4850 (2018)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Menin/Histone-lysine N-methyltransferase MLL


(Homo sapiens (Human))
BDBM50454124
PNG
(CHEMBL3780822)
Show SMILES Cc1c(CN2CCC(CC2)Nc2ncnc3sc(CC(F)(F)F)cc23)ccc2n(Cc3cn[nH]c3)c(cc12)C#N
Show InChI InChI=1S/C28H27F3N8S/c1-17-19(2-3-25-23(17)8-21(11-32)39(25)14-18-12-35-36-13-18)15-38-6-4-20(5-7-38)37-26-24-9-22(10-28(29,30)31)40-27(24)34-16-33-26/h2-3,8-9,12-13,16,20H,4-7,10,14-15H2,1H3,(H,35,36)(H,33,34,37)
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n/an/an/a 9.30n/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Binding affinity to menin (unknown origin) by isothermal titration calorimetry


Bioorg Med Chem 26: 356-365 (2018)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Menin/Histone-lysine N-methyltransferase MLL


(Homo sapiens (Human))
BDBM50489223
PNG
(CHEMBL2314821)
Show SMILES C[C@@H](O)[C@H](NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1cc2ccccc2[nH]1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CO)NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(=O)NCCCCCC(=O)NCCCCCC(=O)N[C@@H](CCCCNC(=O)c1ccc2c(c1)C(=O)OC21C2C=CC(O)=CC2Oc2cc(O)ccc12)C(N)=O
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n/an/an/a 16n/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay


J Med Chem 56: 1113-23 (2013)

More data for this
Ligand-Target Pair
Menin/Histone-lysine N-methyltransferase MLL


(Homo sapiens (Human))
BDBM50454122
PNG
(CHEMBL4206413)
Show SMILES CC1(C)CN=C(S1)N1CCN(CC1)c1ncnc2sc(cc12)C(F)(F)F
Show InChI InChI=1S/C16H18F3N5S2/c1-15(2)8-20-14(26-15)24-5-3-23(4-6-24)12-10-7-11(16(17,18)19)25-13(10)22-9-21-12/h7,9H,3-6,8H2,1-2H3
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n/an/an/a 22n/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Binding affinity to menin (unknown origin) by isothermal titration calorimetry


Bioorg Med Chem 26: 356-365 (2018)

More data for this
Ligand-Target Pair
Menin/Histone-lysine N-methyltransferase MLL


(Homo sapiens (Human))
BDBM50455876
PNG
(CHEMBL4217916)
Show SMILES Cc1c(CN2CCC(CC2)Nc2ncnc3sc(CC(F)(F)F)cc23)ccc2n(Cc3cc[nH]n3)c(cc12)C#N
Show InChI InChI=1S/C28H27F3N8S/c1-17-18(2-3-25-23(17)10-21(13-32)39(25)15-20-4-7-35-37-20)14-38-8-5-19(6-9-38)36-26-24-11-22(12-28(29,30)31)40-27(24)34-16-33-26/h2-4,7,10-11,16,19H,5-6,8-9,12,14-15H2,1H3,(H,35,37)(H,33,34,36)
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n/an/an/a 24n/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity to human C-terminal Avi-tagged menin expressed in Escherichia coli BL21 (DE3) cells by bio-layer interferometry


J Med Chem 61: 4832-4850 (2018)

More data for this
Ligand-Target Pair
Menin


(Homo sapiens (Human))
BDBM50156121
PNG
(CHEMBL3780497)
Show SMILES FC(F)(F)Cc1cc2c(NC3CCN(Cc4ccc5[nH]c(cc5c4)C#N)CC3)ncnc2s1
Show InChI InChI=1S/C23H21F3N6S/c24-23(25,26)10-18-9-19-21(28-13-29-22(19)33-18)31-16-3-5-32(6-4-16)12-14-1-2-20-15(7-14)8-17(11-27)30-20/h1-2,7-9,13,16,30H,3-6,10,12H2,(H,28,29,31)
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n/an/an/a 24n/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity to menin (unknown origin)


J Med Chem 59: 892-913 (2016)


Article DOI: 10.1021/acs.jmedchem.5b01305
BindingDB Entry DOI: 10.7270/Q2M32XM7
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Menin/Histone-lysine N-methyltransferase MLL


(Homo sapiens (Human))
BDBM50496327
PNG
(CHEMBL3126198)
Show SMILES N[C@](C1CCCC1)(C1CCN(CCCOc2ccc(cc2)C#N)CC1)c1ccccc1
Show InChI InChI=1S/C27H35N3O/c28-21-22-11-13-26(14-12-22)31-20-6-17-30-18-15-25(16-19-30)27(29,24-9-4-5-10-24)23-7-2-1-3-8-23/h1-3,7-8,11-14,24-25H,4-6,9-10,15-20,29H2/t27-/m1/s1
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n/an/an/a 85n/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity to human menin by isothermal titration calorimetric analysis


J Med Chem 57: 1543-56 (2014)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Menin/Histone-lysine N-methyltransferase MLL


(Homo sapiens (Human))
BDBM152235
PNG
(US8993552, 70)
Show SMILES CCCc1cc2c(ncnc2s1)N1CCN(CC1)C1=NCC(C)(C)S1
Show InChI InChI=1S/C18H25N5S2/c1-4-5-13-10-14-15(20-12-21-16(14)24-13)22-6-8-23(9-7-22)17-19-11-18(2,3)25-17/h10,12H,4-9,11H2,1-3H3
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n/an/an/a 158n/an/an/an/an/a



China Pharmaceutical University

Curated by ChEMBL


Assay Description
Binding affinity to menin (unknown origin) by isothermal titration calorimetry


Bioorg Med Chem 26: 356-365 (2018)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Menin/Histone-lysine N-methyltransferase MLL


(Homo sapiens (Human))
BDBM50496328
PNG
(CHEMBL3126187)
Show SMILES O[C@](C1CCCC1)(C1CCN(CCCOc2ccc(cc2)C#N)CC1)c1ccccc1
Show InChI InChI=1S/C27H34N2O2/c28-21-22-11-13-26(14-12-22)31-20-6-17-29-18-15-25(16-19-29)27(30,24-9-4-5-10-24)23-7-2-1-3-8-23/h1-3,7-8,11-14,24-25,30H,4-6,9-10,15-20H2/t27-/m1/s1
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n/an/an/a 285n/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity to human menin by isothermal titration calorimetric analysis


J Med Chem 57: 1543-56 (2014)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Menin/Histone-lysine N-methyltransferase MLL


(Homo sapiens (Human))
BDBM50496340
PNG
(CHEMBL3124953)
Show SMILES O[C@@](C1CCCC1)(C1CCN(CCCOc2ccc(cc2)C#N)CC1)c1ccccc1
Show InChI InChI=1S/C27H34N2O2/c28-21-22-11-13-26(14-12-22)31-20-6-17-29-18-15-25(16-19-29)27(30,24-9-4-5-10-24)23-7-2-1-3-8-23/h1-3,7-8,11-14,24-25,30H,4-6,9-10,15-20H2/t27-/m0/s1
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n/an/an/a 952n/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity to human menin by isothermal titration calorimetric analysis


J Med Chem 57: 1543-56 (2014)

More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Menin


(Homo sapiens (Human))
BDBM50366388
PNG
(NEOMYCIN | NEOMYCIN A)
Show SMILES NCC1O[C@@H](O[C@@H]2[C@@H](CO)O[C@@H](O[C@H]3[C@H](O)[C@@H](N)C[C@@H](N)[C@@H]3O[C@H]3O[C@H](CN)[C@@H](O)[C@H](O)[C@H]3N)[C@@H]2O)[C@@H](N)[C@H](O)[C@H]1O
Show InChI InChI=1/C23H46N6O13/c24-2-7-13(32)15(34)10(28)21(37-7)40-18-6(27)1-5(26)12(31)20(18)42-23-17(36)19(9(4-30)39-23)41-22-11(29)16(35)14(33)8(3-25)38-22/h5-23,30-36H,1-4,24-29H2/t5-,6+,7+,8?,9+,10+,11-,12+,13+,14-,15+,16-,17+,18-,19+,20-,21+,22-,23-/s2
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n/an/an/a 1.56E+4n/an/an/an/an/a



Fuzhou University

Curated by ChEMBL


Assay Description
Binding affinity to menin (unknown origin) by isothermal titration calorimetry analysis


Bioorg Med Chem Lett 24: 2090-3 (2014)


Article DOI: 10.1016/j.bmcl.2014.03.055
BindingDB Entry DOI: 10.7270/Q27M09G0
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM50035105
PNG
(1'-{4-[1-(4-fluorophenyl)-1H-3-indolyl]butyl}spiro...)
Show SMILES Fc1ccc(cc1)-n1cc(CCCCN2CCC3(CC2)OCc2ccccc32)c2ccccc12
Show InChI InChI=1S/C30H31FN2O/c31-25-12-14-26(15-13-25)33-21-23(27-9-2-4-11-29(27)33)7-5-6-18-32-19-16-30(17-20-32)28-10-3-1-8-24(28)22-34-30/h1-4,8-15,21H,5-7,16-20,22H2
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0.120n/an/an/an/an/an/an/an/a



Guangdong Medical University

Curated by ChEMBL


Assay Description
Binding affinity to sigma-2 receptor (unknown origin)


Eur J Med Chem 147: 227-237 (2018)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM50216056
PNG
((N-[4-(6,7-dimethoxy-3,4-dihydro-1H-isoquinolin-2-...)
Show SMILES COc1cc2CCN(CCCCNC(=O)c3cc(I)cc(OC)c3OCCF)Cc2cc1OC
Show InChI InChI=1S/C25H32FIN2O5/c1-31-21-12-17-6-10-29(16-18(17)13-22(21)32-2)9-5-4-8-28-25(30)20-14-19(27)15-23(33-3)24(20)34-11-7-26/h12-15H,4-11,16H2,1-3H3,(H,28,30)
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0.260n/an/an/an/an/an/an/an/a



Guangdong Medical University

Curated by ChEMBL


Assay Description
Binding affinity to sigma-2 receptor (unknown origin)


Eur J Med Chem 147: 227-237 (2018)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM50048866
PNG
(1-Cyclohexyl-4-[3-(5-methoxy-1,2,3,4-tetrahydro-na...)
Show SMILES COc1cccc2C(CCCN3CCN(CC3)C3CCCCC3)CCCc12
Show InChI InChI=1/C24H38N2O/c1-27-24-14-6-12-22-20(8-5-13-23(22)24)9-7-15-25-16-18-26(19-17-25)21-10-3-2-4-11-21/h6,12,14,20-21H,2-5,7-11,13,15-19H2,1H3
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0.340n/an/an/an/an/an/an/an/a



Guangdong Medical University

Curated by ChEMBL


Assay Description
Binding affinity to sigma-2 receptor (unknown origin)


Eur J Med Chem 147: 227-237 (2018)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349368
PNG
(US10207991, Ex. Cpd. No. 11)
Show SMILES COc1cc2CN(Cc2cc1OC)[C@H](C)CCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1/C20H23Cl2NO2/c1-13(4-5-14-6-7-17(21)18(22)8-14)23-11-15-9-19(24-2)20(25-3)10-16(15)12-23/h6-10,13H,4-5,11-12H2,1-3H3/t13-/s2
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0.440n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...


US Patent US10207991 (2019)


Article DOI: 10.1021/jm060653b
BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349368
PNG
(US10207991, Ex. Cpd. No. 11)
Show SMILES COc1cc2CN(Cc2cc1OC)[C@H](C)CCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1/C20H23Cl2NO2/c1-13(4-5-14-6-7-17(21)18(22)8-14)23-11-15-9-19(24-2)20(25-3)10-16(15)12-23/h6-10,13H,4-5,11-12H2,1-3H3/t13-/s2
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0.440n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...


US Patent US9796672 (2017)


Article DOI: 10.1021/jm061066t
BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349518
PNG
(US10207991, Ex. Cpd. No. 34)
Show SMILES COc1cc2CN(Cc2cc1OC)C(C)(C)CCc1ccc(F)cc1
Show InChI InChI=1S/C21H26FNO2/c1-21(2,10-9-15-5-7-18(22)8-6-15)23-13-16-11-19(24-3)20(25-4)12-17(16)14-23/h5-8,11-12H,9-10,13-14H2,1-4H3
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0.530n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...


US Patent US9796672 (2017)


Article DOI: 10.1021/jm061066t
BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349518
PNG
(US10207991, Ex. Cpd. No. 34)
Show SMILES COc1cc2CN(Cc2cc1OC)C(C)(C)CCc1ccc(F)cc1
Show InChI InChI=1S/C21H26FNO2/c1-21(2,10-9-15-5-7-18(22)8-6-15)23-13-16-11-19(24-3)20(25-4)12-17(16)14-23/h5-8,11-12H,9-10,13-14H2,1-4H3
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0.530n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...


US Patent US10207991 (2019)


Article DOI: 10.1021/jm060653b
BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349505
PNG
(US10207991, Ex. Cpd. No. 20)
Show SMILES COc1cc2CN(Cc2cc1OC)[C@@H](C)CCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1/C20H23Cl2NO2/c1-13(4-5-14-6-7-17(21)18(22)8-14)23-11-15-9-19(24-2)20(25-3)10-16(15)12-23/h6-10,13H,4-5,11-12H2,1-3H3/t13-/s2
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0.670n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...


US Patent US9796672 (2017)


Article DOI: 10.1021/jm061066t
BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349505
PNG
(US10207991, Ex. Cpd. No. 20)
Show SMILES COc1cc2CN(Cc2cc1OC)[C@@H](C)CCc1ccc(Cl)c(Cl)c1
Show InChI InChI=1/C20H23Cl2NO2/c1-13(4-5-14-6-7-17(21)18(22)8-14)23-11-15-9-19(24-2)20(25-3)10-16(15)12-23/h6-10,13H,4-5,11-12H2,1-3H3/t13-/s2
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0.670n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...


US Patent US10207991 (2019)


Article DOI: 10.1021/jm060653b
BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349569
PNG
(US10207991, Ex. Cpd. No. 87)
Show SMILES CC(C)COc1cc(CCC(C)(C)N2Cc3ccc(cc3C2)S(C)(=O)=O)ccc1O
Show InChI InChI=1S/C24H33NO4S/c1-17(2)16-29-23-12-18(6-9-22(23)26)10-11-24(3,4)25-14-19-7-8-21(30(5,27)28)13-20(19)15-25/h6-9,12-13,17,26H,10-11,14-16H2,1-5H3
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1.10n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...


US Patent US10207991 (2019)


Article DOI: 10.1021/jm060653b
BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349569
PNG
(US10207991, Ex. Cpd. No. 87)
Show SMILES CC(C)COc1cc(CCC(C)(C)N2Cc3ccc(cc3C2)S(C)(=O)=O)ccc1O
Show InChI InChI=1S/C24H33NO4S/c1-17(2)16-29-23-12-18(6-9-22(23)26)10-11-24(3,4)25-14-19-7-8-21(30(5,27)28)13-20(19)15-25/h6-9,12-13,17,26H,10-11,14-16H2,1-5H3
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1.10n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...


US Patent US9796672 (2017)


Article DOI: 10.1021/jm061066t
BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349570
PNG
(US10207991, Ex. Cpd. No. 88)
Show SMILES CC(C)COc1cc(CCC(C)(C)N2Cc3cccc(F)c3C2)ccc1O
Show InChI InChI=1S/C23H30FNO2/c1-16(2)15-27-22-12-17(8-9-21(22)26)10-11-23(3,4)25-13-18-6-5-7-20(24)19(18)14-25/h5-9,12,16,26H,10-11,13-15H2,1-4H3
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1.30n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...


US Patent US10207991 (2019)


Article DOI: 10.1021/jm060653b
BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349570
PNG
(US10207991, Ex. Cpd. No. 88)
Show SMILES CC(C)COc1cc(CCC(C)(C)N2Cc3cccc(F)c3C2)ccc1O
Show InChI InChI=1S/C23H30FNO2/c1-16(2)15-27-22-12-17(8-9-21(22)26)10-11-23(3,4)25-13-18-6-5-7-20(24)19(18)14-25/h5-9,12,16,26H,10-11,13-15H2,1-4H3
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1.30n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...


US Patent US9796672 (2017)


Article DOI: 10.1021/jm061066t
BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349578
PNG
(US10207991, Ex. Cpd. No. 103)
Show SMILES COc1cccc(CCC(C)(C)N2Cc3ccc(cc3C2)S(C)(=O)=O)c1
Show InChI InChI=1S/C21H27NO3S/c1-21(2,11-10-16-6-5-7-19(12-16)25-3)22-14-17-8-9-20(26(4,23)24)13-18(17)15-22/h5-9,12-13H,10-11,14-15H2,1-4H3
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1.40n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...


US Patent US9796672 (2017)


Article DOI: 10.1021/jm061066t
BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349578
PNG
(US10207991, Ex. Cpd. No. 103)
Show SMILES COc1cccc(CCC(C)(C)N2Cc3ccc(cc3C2)S(C)(=O)=O)c1
Show InChI InChI=1S/C21H27NO3S/c1-21(2,11-10-16-6-5-7-19(12-16)25-3)22-14-17-8-9-20(26(4,23)24)13-18(17)15-22/h5-9,12-13H,10-11,14-15H2,1-4H3
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1.40n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...


US Patent US10207991 (2019)


Article DOI: 10.1021/jm060653b
BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349387
PNG
(US10207991, Ex. Cpd. No. 18)
Show SMILES C[C@H](CCc1ccc(Cl)c(Cl)c1)N1Cc2cc3ccccc3cc2C1
Show InChI InChI=1/C22H21Cl2N/c1-15(6-7-16-8-9-21(23)22(24)10-16)25-13-19-11-17-4-2-3-5-18(17)12-20(19)14-25/h2-5,8-12,15H,6-7,13-14H2,1H3/t15-/s2
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1.5n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...


US Patent US9796672 (2017)


Article DOI: 10.1021/jm061066t
BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349387
PNG
(US10207991, Ex. Cpd. No. 18)
Show SMILES C[C@H](CCc1ccc(Cl)c(Cl)c1)N1Cc2cc3ccccc3cc2C1
Show InChI InChI=1/C22H21Cl2N/c1-15(6-7-16-8-9-21(23)22(24)10-16)25-13-19-11-17-4-2-3-5-18(17)12-20(19)14-25/h2-5,8-12,15H,6-7,13-14H2,1H3/t15-/s2
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1.5n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...


US Patent US10207991 (2019)


Article DOI: 10.1021/jm060653b
BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349577
PNG
(US10207991, Ex. Cpd. No. 102)
Show SMILES COc1ccc(CCC(C)(C)N2Cc3ccc(cc3C2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C21H27NO3S/c1-21(2,12-11-16-5-8-19(25-3)9-6-16)22-14-17-7-10-20(26(4,23)24)13-18(17)15-22/h5-10,13H,11-12,14-15H2,1-4H3
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1.80n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...


US Patent US9796672 (2017)


Article DOI: 10.1021/jm061066t
BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM350897
PNG
(US9796672, Example Compound 19)
Show SMILES C[C@H](CCc1ccc(Cl)c(Cl)c1)N1Cc2ccc3ccccc3c2C1
Show InChI InChI=1/C22H21Cl2N/c1-15(6-7-16-8-11-21(23)22(24)12-16)25-13-18-10-9-17-4-2-3-5-19(17)20(18)14-25/h2-5,8-12,15H,6-7,13-14H2,1H3/t15-/s2
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1.80n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...


US Patent US9796672 (2017)


Article DOI: 10.1021/jm061066t
BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349577
PNG
(US10207991, Ex. Cpd. No. 102)
Show SMILES COc1ccc(CCC(C)(C)N2Cc3ccc(cc3C2)S(C)(=O)=O)cc1
Show InChI InChI=1S/C21H27NO3S/c1-21(2,12-11-16-5-8-19(25-3)9-6-16)22-14-17-7-10-20(26(4,23)24)13-18(17)15-22/h5-10,13H,11-12,14-15H2,1-4H3
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1.80n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...


US Patent US10207991 (2019)


Article DOI: 10.1021/jm060653b
BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349478
PNG
(US10207991, Ex. Cpd. No. 19)
Show SMILES CC(CCc1ccc(Cl)c(Cl)c1)N1Cc2ccc3ccccc3c2C1
Show InChI InChI=1/C22H21Cl2N/c1-15(6-7-16-8-11-21(23)22(24)12-16)25-13-18-10-9-17-4-2-3-5-19(17)20(18)14-25/h2-5,8-12,15H,6-7,13-14H2,1H3
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1.80n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...


US Patent US10207991 (2019)


Article DOI: 10.1021/jm060653b
BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349307
PNG
(US10207991, Ex. Cpd. No. 4)
Show SMILES C[C@H](CCc1ccc(Cl)c(Cl)c1)N1Cc2ccc(cc2C1)C(F)(F)F
Show InChI InChI=1/C19H18Cl2F3N/c1-12(2-3-13-4-7-17(20)18(21)8-13)25-10-14-5-6-16(19(22,23)24)9-15(14)11-25/h4-9,12H,2-3,10-11H2,1H3/t12-/s2
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2.20n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...


US Patent US9796672 (2017)


Article DOI: 10.1021/jm061066t
BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349307
PNG
(US10207991, Ex. Cpd. No. 4)
Show SMILES C[C@H](CCc1ccc(Cl)c(Cl)c1)N1Cc2ccc(cc2C1)C(F)(F)F
Show InChI InChI=1/C19H18Cl2F3N/c1-12(2-3-13-4-7-17(20)18(21)8-13)25-10-14-5-6-16(19(22,23)24)9-15(14)11-25/h4-9,12H,2-3,10-11H2,1H3/t12-/s2
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2.20n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...


US Patent US10207991 (2019)


Article DOI: 10.1021/jm060653b
BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349551
PNG
(US10207991, Ex. Cpd. No. 66)
Show SMILES CC(C)(C)Oc1cc(CCC(C)(C)N2Cc3cccc(c3C2)S(C)(=O)=O)ccc1O
Show InChI InChI=1S/C24H33NO4S/c1-23(2,3)29-21-14-17(10-11-20(21)26)12-13-24(4,5)25-15-18-8-7-9-22(19(18)16-25)30(6,27)28/h7-11,14,26H,12-13,15-16H2,1-6H3
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2.60n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...


US Patent US10207991 (2019)


Article DOI: 10.1021/jm060653b
BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349559
PNG
(US10207991, Ex. Cpd. No. 76)
Show SMILES COc1cc(CCC(C)(C)N2Cc3cccc(C(=O)N4CCNCC4)c3C2)ccc1O
Show InChI InChI=1S/C25H33N3O3/c1-25(2,10-9-18-7-8-22(29)23(15-18)31-3)28-16-19-5-4-6-20(21(19)17-28)24(30)27-13-11-26-12-14-27/h4-8,15,26,29H,9-14,16-17H2,1-3H3
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2.60n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...


US Patent US10207991 (2019)


Article DOI: 10.1021/jm060653b
BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349559
PNG
(US10207991, Ex. Cpd. No. 76)
Show SMILES COc1cc(CCC(C)(C)N2Cc3cccc(C(=O)N4CCNCC4)c3C2)ccc1O
Show InChI InChI=1S/C25H33N3O3/c1-25(2,10-9-18-7-8-22(29)23(15-18)31-3)28-16-19-5-4-6-20(21(19)17-28)24(30)27-13-11-26-12-14-27/h4-8,15,26,29H,9-14,16-17H2,1-3H3
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2.60n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...


US Patent US9796672 (2017)


Article DOI: 10.1021/jm061066t
BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349551
PNG
(US10207991, Ex. Cpd. No. 66)
Show SMILES CC(C)(C)Oc1cc(CCC(C)(C)N2Cc3cccc(c3C2)S(C)(=O)=O)ccc1O
Show InChI InChI=1S/C24H33NO4S/c1-23(2,3)29-21-14-17(10-11-20(21)26)12-13-24(4,5)25-15-18-8-7-9-22(19(18)16-25)30(6,27)28/h7-11,14,26H,12-13,15-16H2,1-6H3
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2.60n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...


US Patent US9796672 (2017)


Article DOI: 10.1021/jm061066t
BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349316
PNG
(US10207991, Ex. Cpd. No. 5)
Show SMILES C[C@H](CCc1ccc(Cl)c(Cl)c1)N1Cc2cc(Cl)c(Cl)cc2C1
Show InChI InChI=1/C18H17Cl4N/c1-11(2-3-12-4-5-15(19)16(20)6-12)23-9-13-7-17(21)18(22)8-14(13)10-23/h4-8,11H,2-3,9-10H2,1H3/t11-/s2
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2.70n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...


US Patent US9796672 (2017)


Article DOI: 10.1021/jm061066t
BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349316
PNG
(US10207991, Ex. Cpd. No. 5)
Show SMILES C[C@H](CCc1ccc(Cl)c(Cl)c1)N1Cc2cc(Cl)c(Cl)cc2C1
Show InChI InChI=1/C18H17Cl4N/c1-11(2-3-12-4-5-15(19)16(20)6-12)23-9-13-7-17(21)18(22)8-14(13)10-23/h4-8,11H,2-3,9-10H2,1H3/t11-/s2
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2.70n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...


US Patent US10207991 (2019)


Article DOI: 10.1021/jm060653b
BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Menin/Histone-lysine N-methyltransferase MLL


(Homo sapiens (Human))
BDBM50489239
PNG
(CHEMBL2314823)
Show SMILES C[C@@H](O)[C@H](NC(=O)CNC(=O)[C@@H]1CCCN1C(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](C)NC(=O)[C@@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(=O)NCC(=O)N[C@@H](CCCNC(N)=N)C(=O)N[C@@H](CCCNC(N)=N)C(N)=O
PDB

KEGG

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2.90n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay


J Med Chem 56: 1113-23 (2013)

More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349517
PNG
(US10207991, Ex. Cpd. No. 33)
Show SMILES CC(C)(CCc1ccc(F)cc1)N1Cc2cccc(F)c2C1
Show InChI InChI=1S/C19H21F2N/c1-19(2,11-10-14-6-8-16(20)9-7-14)22-12-15-4-3-5-18(21)17(15)13-22/h3-9H,10-13H2,1-2H3
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3.20n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...


US Patent US9796672 (2017)


Article DOI: 10.1021/jm061066t
BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349517
PNG
(US10207991, Ex. Cpd. No. 33)
Show SMILES CC(C)(CCc1ccc(F)cc1)N1Cc2cccc(F)c2C1
Show InChI InChI=1S/C19H21F2N/c1-19(2,11-10-14-6-8-16(20)9-7-14)22-12-15-4-3-5-18(21)17(15)13-22/h3-9H,10-13H2,1-2H3
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3.20n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...


US Patent US10207991 (2019)


Article DOI: 10.1021/jm060653b
BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349325
PNG
(US10207991, Ex. Cpd. No. 9)
Show SMILES C[C@H](CCc1ccc(Cl)c(Cl)c1)N1Cc2cccc(F)c2C1
Show InChI InChI=1/C18H18Cl2FN/c1-12(5-6-13-7-8-16(19)17(20)9-13)22-10-14-3-2-4-18(21)15(14)11-22/h2-4,7-9,12H,5-6,10-11H2,1H3/t12-/s2
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3.60n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...


US Patent US9796672 (2017)


Article DOI: 10.1021/jm061066t
BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349519
PNG
(US10207991, Ex. Cpd. No. 35)
Show SMILES CC(C)(CCc1ccc(F)cc1)N1Cc2ccc(F)cc2C1
Show InChI InChI=1S/C19H21F2N/c1-19(2,10-9-14-3-6-17(20)7-4-14)22-12-15-5-8-18(21)11-16(15)13-22/h3-8,11H,9-10,12-13H2,1-2H3
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3.60n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
Radioligand binding assays for Sigma-1 receptors and Sigma-2 receptors were carried out by a commercial contract research organization. For Sigma-1 b...


US Patent US9796672 (2017)


Article DOI: 10.1021/jm061066t
BindingDB Entry DOI: 10.7270/Q2X92DFN
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349519
PNG
(US10207991, Ex. Cpd. No. 35)
Show SMILES CC(C)(CCc1ccc(F)cc1)N1Cc2ccc(F)cc2C1
Show InChI InChI=1S/C19H21F2N/c1-19(2,10-9-14-3-6-17(20)7-4-14)22-12-15-5-8-18(21)11-16(15)13-22/h3-8,11H,9-10,12-13H2,1-2H3
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UniChem
Article
US Patent
3.60n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...


US Patent US10207991 (2019)


Article DOI: 10.1021/jm060653b
BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Sigma intracellular receptor 2


(Homo sapiens (Human))
BDBM349325
PNG
(US10207991, Ex. Cpd. No. 9)
Show SMILES C[C@H](CCc1ccc(Cl)c(Cl)c1)N1Cc2cccc(F)c2C1
Show InChI InChI=1/C18H18Cl2FN/c1-12(5-6-13-7-8-16(19)17(20)9-13)22-10-14-3-2-4-18(21)15(14)11-22/h2-4,7-9,12H,5-6,10-11H2,1H3/t12-/s2
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UniChem
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3.60n/an/an/an/an/an/an/an/a



COGNITION THERAPEUTICS, INC.

US Patent


Assay Description
The affinity of candidate sigma-2 ligand compounds at sigma-1 and sigma-2 receptors was also determined by displacement of different known labeled si...


US Patent US10207991 (2019)


Article DOI: 10.1021/jm060653b
BindingDB Entry DOI: 10.7270/Q2BV7JRG
More data for this
Ligand-Target Pair
Menin/Histone-lysine N-methyltransferase MLL


(Homo sapiens (Human))
BDBM50489254
PNG
(CHEMBL2314819)
Show SMILES N[C@H]1CCCCCCCCNC(=O)[C@@H]2CCCN2C(=O)[C@H](CCCNC(N)=N)NC(=O)C2(CCC2)NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2cc(F)cc(F)c2)NC1=O
Show InChI InChI=1S/C40H60F2N10O6/c41-26-21-25(22-27(42)24-26)23-30-37(57)52-20-9-14-32(52)35(55)50-40(15-10-16-40)38(58)49-29(12-7-18-47-39(44)45)36(56)51-19-8-13-31(51)34(54)46-17-6-4-2-1-3-5-11-28(43)33(53)48-30/h21-22,24,28-32H,1-20,23,43H2,(H,46,54)(H,48,53)(H,49,58)(H,50,55)(H4,44,45,47)/t28-,29-,30-,31-,32-/m0/s1
PDB

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4.70n/an/an/an/an/an/an/an/a



University of Michigan

Curated by ChEMBL


Assay Description
Binding affinity to menin (unknown origin) after 60 mins by fluorescence polarization assay


J Med Chem 56: 1113-23 (2013)

More data for this
Ligand-Target Pair
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