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Compile Data Set for Download or QSAR

Found 2 hits Enz. Inhib. hit(s) with Target = 'Paired box protein 2 (Pax2)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Paired box protein 2 (Pax2)


(Homo sapiens (Human))
BDBM218809
PNG
(EG1)
Show SMILES COc1ccccc1C(=O)Nc1ccc(cc1)C(=O)Nc1ccccc1C(O)=O
Show InChI InChI=1S/C22H18N2O5/c1-29-19-9-5-3-7-17(19)21(26)23-15-12-10-14(11-13-15)20(25)24-18-8-4-2-6-16(18)22(27)28/h2-13H,1H3,(H,23,26)(H,24,25)(H,27,28)
PDB

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PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 1.35E+3n/an/an/an/an/a



University of Michigan



Assay Description
For this experiment, we immobilized the biotinylated recombinant Pax2 paired domain, containing amino acids 1−81, onto streptavidin biosensors ...


ACS Chem Biol 12: 724-734 (2017)


Article DOI: 10.1021/acschembio.6b00782
BindingDB Entry DOI: 10.7270/Q28W3C4J
More data for this
Ligand-Target Pair
Paired box protein 2 (Pax2)


(Homo sapiens (Human))
BDBM218809
PNG
(EG1)
Show SMILES COc1ccccc1C(=O)Nc1ccc(cc1)C(=O)Nc1ccccc1C(O)=O
Show InChI InChI=1S/C22H18N2O5/c1-29-19-9-5-3-7-17(19)21(26)23-15-12-10-14(11-13-15)20(25)24-18-8-4-2-6-16(18)22(27)28/h2-13H,1H3,(H,23,26)(H,24,25)(H,27,28)
PDB

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
Article
PubMed
n/an/an/a 1.50E+3n/an/an/an/an/a



University of Michigan



Assay Description
For this experiment, we immobilized the biotinylated recombinant Pax2 paired domain, containing amino acids 1−81, onto streptavidin biosensors ...


ACS Chem Biol 12: 724-734 (2017)


Article DOI: 10.1021/acschembio.6b00782
BindingDB Entry DOI: 10.7270/Q28W3C4J
More data for this
Ligand-Target Pair