Affinity DataKd: 0.280nMAssay Description:Displacement of [20-3H] phorbol 12, 13-dibutylate from recombinant PKCalpha (unknown origin) in presence of 100 ug/ml 100% phosphatidylserineMore data for this Ligand-Target Pair
Affinity DataKd: 0.280nMAssay Description:Binding affinity for human Protein kinase C alpha with [Ca2+]More data for this Ligand-Target Pair
Affinity DataKd: 0.800nMAssay Description:Dissociation constant for Protein kinase C alphaMore data for this Ligand-Target Pair
Affinity DataKd: 1.10nMAssay Description:Binding affinity for protein kinase C Alpha-C1A domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.10nMAssay Description:Inhibition of [3H]PDBu binding to PKC alpha C1A peptideMore data for this Ligand-Target Pair
Affinity DataKd: 1.10nMAssay Description:Displacement of [3H]- PDBu from Protein kinase C epsilon C1b domainMore data for this Ligand-Target Pair
Affinity DataKd: 1.10nMAssay Description:Binding affinity to PKCalpha-C1A domain peptide using [3H]-labeled compoundMore data for this Ligand-Target Pair
Affinity DataKd: 1.40nMAssay Description:Displacement of [20-3H] phorbol 12, 13-dibutylate from recombinant PKCalpha (unknown origin) in presence of nuclear membrane mimetic lipid mixtureMore data for this Ligand-Target Pair
Affinity DataKd: 3.40nMpH: 7.4 T: 2°CAssay Description:[3H]PDBu binding to the C1 domains of MRCK alpha/beta and PKC alpha/delta was measured using the polyethylene glycol precipitation assay.More data for this Ligand-Target Pair
Affinity DataKd: 6.40nMAssay Description:Binding affinity to PKCalpha (unknown origin) using Lys-Arg-Thr-Leu-Arg-Arg as substrate after 8 mins in presence of [gamma-32P]ATP by liquid scintil...More data for this Ligand-Target Pair
Affinity DataKd: 7.40nMAssay Description:Displacement of [3H]-PDBu from protein kinase C Alpha-C1A domainMore data for this Ligand-Target Pair
Affinity DataKd: 7.40nMAssay Description:Binding affinity for Protein kinase C alpha C1b domainMore data for this Ligand-Target Pair
Affinity DataKd: 43nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PRKCA (unknown origin) expressed in baculovirus infected Sf9 insect cells ...More data for this Ligand-Target Pair
Affinity DataKd: 47nMAssay Description:Displacement of [3H]-PDBu from Protein kinase C alpha C1b domainMore data for this Ligand-Target Pair
Affinity DataKd: 50nMAssay Description:Average Binding Constant for PRKACA; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: 92nMAssay Description:Binding affinity to recombinant full-length N-terminal His-FLAG-GST-tagged PRKCA (unknown origin) expressed in baculovirus infected Sf9 insect cells ...More data for this Ligand-Target Pair
Affinity DataKd: 220nMAssay Description:Binding affinity to PKAC-alphaMore data for this Ligand-Target Pair
Affinity DataKd: 720nMAssay Description:Binding affinity to PKAC-alphaMore data for this Ligand-Target Pair
Affinity DataKd: 6.00E+3nMAssay Description:Average Binding Constant for PRKACA; NA=Not Active at 10 uMMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to PKAC-alphaMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to PKAC-alphaMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to PKAC-alphaMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to PKAC-alphaMore data for this Ligand-Target Pair
Affinity DataKd: >1.00E+4nMAssay Description:Binding affinity to PKAC-alphaMore data for this Ligand-Target Pair
Affinity DataKi: 0.140nMAssay Description:Displacement of [3H]-PDBU from protein kinase C-alphaMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Bos taurus (bovine))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 0.200nMAssay Description:Ability to displace bound [20-3H]-PDBU from a recombinant single isozyme (PKCalpha) in the presence of phosphatidylserineMore data for this Ligand-Target Pair
Affinity DataKi: 0.200nMAssay Description:Binding Affinity against protein kinase C alphaMore data for this Ligand-Target Pair
Affinity DataKi: 0.260nMAssay Description:Inhibition of [3H]PDBu binding to PKCalpha C1A domainMore data for this Ligand-Target Pair
Affinity DataKi: 0.400nMAssay Description:Inhibition of [3H]PDBu binding to PKC alpha C1A peptideMore data for this Ligand-Target Pair
Affinity DataKi: 0.480nMAssay Description:Inhibition of [20-3H]phorbol 12,13-dibutyrate binding to human PKCalpha by scintillation counting based poly(ethylene) glycol precipitation assayMore data for this Ligand-Target Pair
Affinity DataKi: 0.5nMAssay Description:Displacement of [3H]- PDBu from recombinant PKC alpha expressed in baculovirusMore data for this Ligand-Target Pair
Affinity DataKi: 0.540nMAssay Description:Displacement of [3H]-PDBU from protein kinase C-alphaMore data for this Ligand-Target Pair
Affinity DataKi: 0.780nMAssay Description:Binding affinity (Ki) towards Protein kinase CMore data for this Ligand-Target Pair
Affinity DataKi: 0.930nMAssay Description:Inhibition of human Protein kinase C alpha with [Ca2+]More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Displacement of [3H]PDBu from PKCalpha C1A domain (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1nMAssay Description:Reversible competitive inhibition of PKCalpha (unknown origin)More data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Affinity for protein kinase C alphaMore data for this Ligand-Target Pair
Affinity DataKi: 1.5nMAssay Description:Displacement of [20-3H]PDBu from recombinant PKC alpha in presence of phosphatidylserineMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of [3H]PDBu form PKCalphaMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Displacement of 3[H]PDBu from Protein kinase C alpha C1a domainMore data for this Ligand-Target Pair
TargetProtein kinase C alpha type(Bos taurus (bovine))
National Cancer Institute-Frederick
Curated by ChEMBL
National Cancer Institute-Frederick
Curated by ChEMBL
Affinity DataKi: 1.80nMAssay Description:Tested for ability to displace [20e3] phorbol 12,13- dibutyrate binding from recombinant bovine Protein kinase C alpha in presence of [Ca2+]More data for this Ligand-Target Pair
Affinity DataKi: 1.80nMAssay Description:Affinity for protein kinase C alphaMore data for this Ligand-Target Pair