Affinity DataKd: 10.3nMAssay Description:Binding affinity to recombinant human Smo receptor assessed as dissociation constant at equilibrium by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 10.6nMAssay Description:Binding affinity to recombinant human Smo receptor assessed as dissociation constant at equilibrium by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 12.4nMAssay Description:Binding affinity to wild type Smo expressed in U2OS cells by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKd: 97.5nMAssay Description:Binding affinity to recombinant human Smo receptor assessed as dissociation constant at equilibrium by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.21E+4nMAssay Description:Binding affinity to recombinant human Smo receptor assessed as dissociation constant at equilibrium by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKd: 1.36E+4nMAssay Description:Binding affinity to recombinant human Smo receptor assessed as dissociation constant at equilibrium by SPR analysisMore data for this Ligand-Target Pair
Affinity DataKi: 6nMAssay Description:Displacement of [3H]cyclopamine from wild type Smo expressed in U2OS cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 12.7nMAssay Description:Displacement of [3H]cyclopamine from wild type Smo expressed in U2OS cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 16.2nMAssay Description:Displacement of [3H]cyclopamine from wild type Smo expressed in U2OS cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 28nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 30nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 33nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 37.9nMAssay Description:Displacement of [3H]cyclopamine from wild type Smo expressed in U2OS cells after 2 hrs by scintillation countingMore data for this Ligand-Target Pair
Affinity DataKi: 42nMAssay Description:Displacement of [3H]-cyclopamine from human wild-type SMO receptor expressed in HEK293T cell membranes by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 45nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 55nMAssay Description:Displacement of BODIPY-LY from SMO (unknown origin) expressed in HEK293F cells measured after 15 mins by flow cytometric analysisMore data for this Ligand-Target Pair
Affinity DataKi: 60nMAssay Description:Displacement of [3H]-cyclopamine from human wild-type SMO receptor expressed in HEK293T cell membranes by liquid scintillation spectrometryMore data for this Ligand-Target Pair
Affinity DataEC50: 1.50E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
Affinity DataEC50: 600nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
Affinity DataEC50: 900nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
Affinity DataEC50: 800nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
Affinity DataEC50: 1.20E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
Affinity DataEC50: 3.60E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
Affinity DataEC50: 360nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
Affinity DataEC50: 600nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
Affinity DataEC50: 5.80E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
Affinity DataEC50: 800nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
Affinity DataEC50: 130nMAssay Description:Agonist activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosp...More data for this Ligand-Target Pair
Affinity DataEC50: 700nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
Affinity DataEC50: 800nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
Affinity DataEC50: 2.00E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
Affinity DataEC50: 6.50E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
Affinity DataEC50: 3.40E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
Affinity DataEC50: 30nMAssay Description:Agonist activity at Smo in mouse NIH/3T3 cells transfected with Gli-dependent firefly luciferase reporter assessed as stimulation of Gli transcriptio...More data for this Ligand-Target Pair
Affinity DataEC50: 4.90E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
Affinity DataEC50: 3.10E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
Affinity DataEC50: 2.60E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
Affinity DataEC50: 2.40E+3nMAssay Description:Activity at Smo in mouse C3H10T1/2 cells assessed as induction of cell differentiation into osteoblast incubated for 6 days by alkaline phosphatase a...More data for this Ligand-Target Pair
Affinity DataIC50: 18.7nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
Affinity DataIC50: 75nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
Affinity DataIC50: 32.1nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
Affinity DataIC50: 32.9nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
Affinity DataIC50: 18.8nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair
Affinity DataIC50: 110nMT: 2°CAssay Description:For the binding competition assay, 100 μL of Assay Buffer was added to all the wells of a 96 well GF/B filter plate (Millipore MultiScreen-HTS-F...More data for this Ligand-Target Pair