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Compile Data Set for Download or QSAR

Found 281 hits Enz. Inhib. hit(s) with Target = 'AXL receptor tyrosine kinase'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308065
PNG
(US9649309, Compound UNC1844A)
Show SMILES CCCCNc1ncc(C(=O)NCCCCO)c(NC2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C19H33N5O3/c1-2-3-10-21-19-22-13-16(18(27)20-11-4-5-12-25)17(24-19)23-14-6-8-15(26)9-7-14/h13-15,25-26H,2-12H2,1H3,(H,20,27)(H2,21,22,23,24)/t14?,15-
PDB

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US Patent
n/an/a 1.08E+3n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308066
PNG
(US9649309, Compound UNC1845A)
Show SMILES CCCCNc1ncc(C(=O)NCCCOC)c(NC2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C19H33N5O3/c1-3-4-10-21-19-22-13-16(18(26)20-11-5-12-27-2)17(24-19)23-14-6-8-15(25)9-7-14/h13-15,25H,3-12H2,1-2H3,(H,20,26)(H2,21,22,23,24)/t14?,15-
PDB

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n/an/a 1.03E+3n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308069
PNG
(US9649309, Compound UNC1846A)
Show SMILES CCCCNc1ncc(C(=O)Nc2ccc(CCO)cc2)c(NC2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C23H33N5O3/c1-2-3-13-24-23-25-15-20(21(28-23)26-17-8-10-19(30)11-9-17)22(31)27-18-6-4-16(5-7-18)12-14-29/h4-7,15,17,19,29-30H,2-3,8-14H2,1H3,(H,27,31)(H2,24,25,26,28)/t17?,19-
PDB

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n/an/a 1.07E+3n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308070
PNG
(US9649309, Compound UNC1849A)
Show SMILES CCCCNc1ncc(C(=O)NCc2ccncc2)c(NC2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C21H30N6O2/c1-2-3-10-23-21-25-14-18(20(29)24-13-15-8-11-22-12-9-15)19(27-21)26-16-4-6-17(28)7-5-16/h8-9,11-12,14,16-17,28H,2-7,10,13H2,1H3,(H,24,29)(H2,23,25,26,27)/t16?,17-
PDB

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n/an/a 1.74E+3n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308071
PNG
(US9649309, Compound UNC1850A)
Show SMILES CCCCNc1ncc(C(=O)NCCc2ccc(F)cc2)c(NC2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C23H32FN5O2/c1-2-3-13-26-23-27-15-20(21(29-23)28-18-8-10-19(30)11-9-18)22(31)25-14-12-16-4-6-17(24)7-5-16/h4-7,15,18-19,30H,2-3,8-14H2,1H3,(H,25,31)(H2,26,27,28,29)/t18?,19-
PDB

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n/an/a 1.22E+3n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308073
PNG
(US9649309, Compound UNC1839A)
Show SMILES CCCCNc1ncc(C(=O)NCCCN2CCOCC2)c(NC2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C22H38N6O3/c1-2-3-9-24-22-25-16-19(20(27-22)26-17-5-7-18(29)8-6-17)21(30)23-10-4-11-28-12-14-31-15-13-28/h16-18,29H,2-15H2,1H3,(H,23,30)(H2,24,25,26,27)/t17?,18-
PDB

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n/an/a 1.07E+3n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308074
PNG
(US9649309, Compound UNC1840A)
Show SMILES CCCCNc1ncc(C(=O)NCCCN2CCOCC2)c(NCCCC)n1
Show InChI InChI=1S/C20H36N6O2/c1-3-5-8-21-18-17(16-24-20(25-18)23-9-6-4-2)19(27)22-10-7-11-26-12-14-28-15-13-26/h16H,3-15H2,1-2H3,(H,22,27)(H2,21,23,24,25)
PDB

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n/an/a 4.64E+3n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308075
PNG
(US9649309, Compound UNC2579A)
Show SMILES CCCCNc1ncc(C(=O)NCc2ccccn2)c(NC2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C21H30N6O2/c1-2-3-11-23-21-25-14-18(20(29)24-13-16-6-4-5-12-22-16)19(27-21)26-15-7-9-17(28)10-8-15/h4-6,12,14-15,17,28H,2-3,7-11,13H2,1H3,(H,24,29)(H2,23,25,26,27)/t15?,17-
PDB

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n/an/a 381n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308076
PNG
(US9649309, Compound UNC2580A)
Show SMILES CCCCNc1ncc(C(=O)NCc2cccnc2)c(NC2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C21H30N6O2/c1-2-3-11-23-21-25-14-18(20(29)24-13-15-5-4-10-22-12-15)19(27-21)26-16-6-8-17(28)9-7-16/h4-5,10,12,14,16-17,28H,2-3,6-9,11,13H2,1H3,(H,24,29)(H2,23,25,26,27)/t16?,17-
PDB

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n/an/a 233n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308077
PNG
(US9649309, Compound UNC2581A)
Show SMILES CCCCNc1ncc(C(=O)NCc2ccc(cc2)N(C)C)c(NC2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C24H36N6O2/c1-4-5-14-25-24-27-16-21(22(29-24)28-18-8-12-20(31)13-9-18)23(32)26-15-17-6-10-19(11-7-17)30(2)3/h6-7,10-11,16,18,20,31H,4-5,8-9,12-15H2,1-3H3,(H,26,32)(H2,25,27,28,29)/t18?,20-
PDB

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n/an/a 643n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308078
PNG
(US9649309, Compound UNC2582A)
Show SMILES CCCCNc1ncc(C(=O)NCc2ccccc2C(F)(F)F)c(NC2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C23H30F3N5O2/c1-2-3-12-27-22-29-14-18(20(31-22)30-16-8-10-17(32)11-9-16)21(33)28-13-15-6-4-5-7-19(15)23(24,25)26/h4-7,14,16-17,32H,2-3,8-13H2,1H3,(H,28,33)(H2,27,29,30,31)/t16?,17-
PDB

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n/an/a 436n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308296
PNG
(US9649309, Compound UNC3190A)
Show SMILES CCCCNc1ncc(c(NC2CC[C@H](O)CC2)n1)-c1cc(NCCC)ncn1
Show InChI InChI=1S/C21H33N7O/c1-3-5-11-23-21-24-13-17(18-12-19(22-10-4-2)26-14-25-18)20(28-21)27-15-6-8-16(29)9-7-15/h12-16,29H,3-11H2,1-2H3,(H,22,25,26)(H2,23,24,27,28)/t15?,16-
PDB

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n/an/a 90n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308297
PNG
(US9649309, Compound UNC3193A)
Show SMILES CCCCNc1ncc(c(NC2CC[C@H](O)CC2)n1)-c1cc(NC2CC2)ncn1
Show InChI InChI=1S/C21H31N7O/c1-2-3-10-22-21-23-12-17(18-11-19(25-13-24-18)26-14-4-5-14)20(28-21)27-15-6-8-16(29)9-7-15/h11-16,29H,2-10H2,1H3,(H,24,25,26)(H2,22,23,27,28)/t15?,16-
PDB

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n/an/a 115n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308298
PNG
(US9649309, Compound UNC3195A)
Show SMILES CCCCNc1ncc(c(NC2CC[C@H](O)CC2)n1)-c1cc(ncn1)N1CCCC1
Show InChI InChI=1S/C22H33N7O/c1-2-3-10-23-22-24-14-18(21(28-22)27-16-6-8-17(30)9-7-16)19-13-20(26-15-25-19)29-11-4-5-12-29/h13-17,30H,2-12H2,1H3,(H2,23,24,27,28)/t16?,17-
PDB

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n/an/a 230n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308299
PNG
(US9649309, Compound UNC3194A)
Show SMILES CCCCNc1ncc(c(NC2CC[C@H](O)CC2)n1)-c1cc(NC2CCCCC2)ncn1
Show InChI InChI=1S/C24H37N7O/c1-2-3-13-25-24-26-15-20(23(31-24)30-18-9-11-19(32)12-10-18)21-14-22(28-16-27-21)29-17-7-5-4-6-8-17/h14-19,32H,2-13H2,1H3,(H,27,28,29)(H2,25,26,30,31)/t18?,19-
PDB

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n/an/a 239n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308300
PNG
(US9649309, Compound UNC3199A)
Show SMILES CCCCNc1ncc(c(NC2CC[C@H](O)CC2)n1)-c1cc(NC2CCCC2)ncn1
Show InChI InChI=1S/C23H35N7O/c1-2-3-12-24-23-25-14-19(22(30-23)29-17-8-10-18(31)11-9-17)20-13-21(27-15-26-20)28-16-6-4-5-7-16/h13-18,31H,2-12H2,1H3,(H,26,27,28)(H2,24,25,29,30)/t17?,18-
PDB

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n/an/a 847n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308301
PNG
(US9649309, Compound UNC3198A)
Show SMILES CCCCNc1ncc(c(NC2CC[C@H](O)CC2)n1)-c1cc(ncn1)N1CCCCC1
Show InChI InChI=1S/C23H35N7O/c1-2-3-11-24-23-25-15-19(22(29-23)28-17-7-9-18(31)10-8-17)20-14-21(27-16-26-20)30-12-5-4-6-13-30/h14-18,31H,2-13H2,1H3,(H2,24,25,28,29)/t17?,18-
PDB

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n/an/a 3.74E+3n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308302
PNG
(US9649309, Compound UNC3196A)
Show SMILES CCCCNc1ncc(c(NC2CC[C@H](O)CC2)n1)-c1cc(ncn1)N1CCOCC1
Show InChI InChI=1S/C22H33N7O2/c1-2-3-8-23-22-24-14-18(21(28-22)27-16-4-6-17(30)7-5-16)19-13-20(26-15-25-19)29-9-11-31-12-10-29/h13-17,30H,2-12H2,1H3,(H2,23,24,27,28)/t16?,17-
PDB

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n/an/a 1.00E+3n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308303
PNG
(US9649309, Compound UNC3197A)
Show SMILES CCCCNc1ncc(c(NC2CC[C@H](O)CC2)n1)-c1cc(ncn1)N1CCN(C)CC1
Show InChI InChI=1S/C23H36N8O/c1-3-4-9-24-23-25-15-19(22(29-23)28-17-5-7-18(32)8-6-17)20-14-21(27-16-26-20)31-12-10-30(2)11-13-31/h14-18,32H,3-13H2,1-2H3,(H2,24,25,28,29)/t17?,18-
PDB

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n/an/a 1.17E+3n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308304
PNG
(US9649309, Compound UNC3203A)
Show SMILES O[C@H]1CCC(CC1)Nc1nc(Nc2ccc(cc2)C#C)ncc1-c1ccccn1
Show InChI InChI=1S/C23H23N5O/c1-2-16-6-8-18(9-7-16)27-23-25-15-20(21-5-3-4-14-24-21)22(28-23)26-17-10-12-19(29)13-11-17/h1,3-9,14-15,17,19,29H,10-13H2,(H2,25,26,27,28)/t17?,19-
PDB

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n/an/a 3.70n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308305
PNG
(US9649309, Compound UNC4223A)
Show SMILES CCCCNc1ncc(-c2ncc(CN3CCCC3)s2)c(NC2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C22H34N6OS/c1-2-3-10-23-22-25-14-19(20(27-22)26-16-6-8-17(29)9-7-16)21-24-13-18(30-21)15-28-11-4-5-12-28/h13-14,16-17,29H,2-12,15H2,1H3,(H2,23,25,26,27)/t16?,17-
PDB

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n/an/a 14n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308306
PNG
(US9649309, Compound UNC4261A)
Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1cc(NC2CCCCCC2)ncn1
Show InChI InChI=1S/C25H39N7O/c1-2-3-14-26-25-27-16-21(24(32-25)31-19-10-12-20(33)13-11-19)22-15-23(29-17-28-22)30-18-8-6-4-5-7-9-18/h15-20,33H,2-14H2,1H3,(H,28,29,30)(H2,26,27,31,32)/t19-,20-
PDB

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n/an/a 380n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308307
PNG
(US9649309, Compound UNC4268A)
Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1cc(Nc2ccccc2)ncn1
Show InChI InChI=1S/C24H31N7O/c1-2-3-13-25-24-26-15-20(23(31-24)30-18-9-11-19(32)12-10-18)21-14-22(28-16-27-21)29-17-7-5-4-6-8-17/h4-8,14-16,18-19,32H,2-3,9-13H2,1H3,(H,27,28,29)(H2,25,26,30,31)/t18-,19-
PDB

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n/an/a 82n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308308
PNG
(US9649309, Compound UNC4269A)
Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1cc(Nc2ccc(OC)cc2)ncn1
Show InChI InChI=1S/C25H33N7O2/c1-3-4-13-26-25-27-15-21(24(32-25)31-18-5-9-19(33)10-6-18)22-14-23(29-16-28-22)30-17-7-11-20(34-2)12-8-17/h7-8,11-12,14-16,18-19,33H,3-6,9-10,13H2,1-2H3,(H,28,29,30)(H2,26,27,31,32)/t18-,19-
PDB

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n/an/a 234n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308309
PNG
(US9649309, Compound UNC4270A)
Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1cc(Nc2cccc(OC)c2)ncn1
Show InChI InChI=1S/C25H33N7O2/c1-3-4-12-26-25-27-15-21(24(32-25)31-17-8-10-19(33)11-9-17)22-14-23(29-16-28-22)30-18-6-5-7-20(13-18)34-2/h5-7,13-17,19,33H,3-4,8-12H2,1-2H3,(H,28,29,30)(H2,26,27,31,32)/t17-,19-
PDB

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n/an/a 121n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308079
PNG
(US9649309, Compound UNC2583A)
Show SMILES CCCCNc1ncc(C(=O)NCc2ccc(cc2)C(F)(F)F)c(NC2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C23H30F3N5O2/c1-2-3-12-27-22-29-14-19(20(31-22)30-17-8-10-18(32)11-9-17)21(33)28-13-15-4-6-16(7-5-15)23(24,25)26/h4-7,14,17-18,32H,2-3,8-13H2,1H3,(H,28,33)(H2,27,29,30,31)/t17?,18-
PDB

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n/an/a 527n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308080
PNG
(US9649309, Compound UNC2591A)
Show SMILES CCCCNc1ncc(C(=O)NCc2ccc(cc2)-c2ccccc2)c(NC2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C28H35N5O2/c1-2-3-17-29-28-31-19-25(26(33-28)32-23-13-15-24(34)16-14-23)27(35)30-18-20-9-11-22(12-10-20)21-7-5-4-6-8-21/h4-12,19,23-24,34H,2-3,13-18H2,1H3,(H,30,35)(H2,29,31,32,33)/t23?,24-
PDB

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n/an/a 1.51E+3n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308082
PNG
(US9649309, Compound UNC2592A)
Show SMILES CCCCNc1ncc(C(=O)NCc2cccc(OC)c2)c(N[C@H]2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C23H33N5O3/c1-3-4-12-24-23-26-15-20(21(28-23)27-17-8-10-18(29)11-9-17)22(30)25-14-16-6-5-7-19(13-16)31-2/h5-7,13,15,17-18,29H,3-4,8-12,14H2,1-2H3,(H,25,30)(H2,24,26,27,28)/t17-,18-
PDB

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The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308083
PNG
(US9649309, Compound UNC2584A)
Show SMILES CCCCNc1ncc(C(=O)NCc2cc(OC)cc(OC)c2)c(N[C@H]2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C24H35N5O4/c1-4-5-10-25-24-27-15-21(22(29-24)28-17-6-8-18(30)9-7-17)23(31)26-14-16-11-19(32-2)13-20(12-16)33-3/h11-13,15,17-18,30H,4-10,14H2,1-3H3,(H,26,31)(H2,25,27,28,29)/t17-,18-
PDB

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n/an/a 273n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308084
PNG
(US9649309, Compound UNC2585A)
Show SMILES CCCCNc1ncc(C(=O)NCc2ccc(OC)cc2OC)c(N[C@H]2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C24H35N5O4/c1-4-5-12-25-24-27-15-20(22(29-24)28-17-7-9-18(30)10-8-17)23(31)26-14-16-6-11-19(32-2)13-21(16)33-3/h6,11,13,15,17-18,30H,4-5,7-10,12,14H2,1-3H3,(H,26,31)(H2,25,27,28,29)/t17-,18-
PDB

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n/an/a 1.10E+3n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308085
PNG
(US9649309, Compound UNC2593A)
Show SMILES CCCCNc1ncc(C(=O)NCc2cccc(c2)N2CCCC2)c(N[C@H]2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C26H38N6O2/c1-2-3-13-27-26-29-18-23(24(31-26)30-20-9-11-22(33)12-10-20)25(34)28-17-19-7-6-8-21(16-19)32-14-4-5-15-32/h6-8,16,18,20,22,33H,2-5,9-15,17H2,1H3,(H,28,34)(H2,27,29,30,31)/t20-,22-
PDB

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n/an/a 559n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308086
PNG
(US9649309, Compound UNC2587A)
Show SMILES CCCCNc1ncc(C(=O)NCc2ccc(CN3CCN(C)CC3)cc2)c(N[C@H]2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C28H43N7O2/c1-3-4-13-29-28-31-19-25(26(33-28)32-23-9-11-24(36)12-10-23)27(37)30-18-21-5-7-22(8-6-21)20-35-16-14-34(2)15-17-35/h5-8,19,23-24,36H,3-4,9-18,20H2,1-2H3,(H,30,37)(H2,29,31,32,33)/t23-,24-
PDB

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n/an/a 291n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308087
PNG
(US9649309, Compound UNC2586A)
Show SMILES CCCCNc1ncc(C(=O)NCc2cc3ccccc3o2)c(N[C@H]2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C24H31N5O3/c1-2-3-12-25-24-27-15-20(22(29-24)28-17-8-10-18(30)11-9-17)23(31)26-14-19-13-16-6-4-5-7-21(16)32-19/h4-7,13,15,17-18,30H,2-3,8-12,14H2,1H3,(H,26,31)(H2,25,27,28,29)/t17-,18-
PDB

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n/an/a 477n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308088
PNG
(US9649309, Compound UNC2594A)
Show SMILES CCCCNc1ncc(C(=O)NCc2ccc(nc2)-n2cccn2)c(N[C@H]2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C24H32N8O2/c1-2-3-11-25-24-28-16-20(22(31-24)30-18-6-8-19(33)9-7-18)23(34)27-15-17-5-10-21(26-14-17)32-13-4-12-29-32/h4-5,10,12-14,16,18-19,33H,2-3,6-9,11,15H2,1H3,(H,27,34)(H2,25,28,30,31)/t18-,19-
PDB

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n/an/a 118n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308089
PNG
(US9649309, Compound UNC2595A)
Show SMILES CCCCNc1ncc(C(=O)NCc2ccc(NC(=O)CC)nc2)c(N[C@H]2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C24H35N7O3/c1-3-5-12-25-24-28-15-19(22(31-24)29-17-7-9-18(32)10-8-17)23(34)27-14-16-6-11-20(26-13-16)30-21(33)4-2/h6,11,13,15,17-18,32H,3-5,7-10,12,14H2,1-2H3,(H,27,34)(H,26,30,33)(H2,25,28,29,31)/t17-,18-
PDB

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n/an/a 215n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308090
PNG
(US9649309, Compound UNC2598A)
Show SMILES CCCCNc1ncc(C(=O)NCc2ccc(nc2)-c2cccs2)c(N[C@H]2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C25H32N6O2S/c1-2-3-12-26-25-29-16-20(23(31-25)30-18-7-9-19(32)10-8-18)24(33)28-15-17-6-11-21(27-14-17)22-5-4-13-34-22/h4-6,11,13-14,16,18-19,32H,2-3,7-10,12,15H2,1H3,(H,28,33)(H2,26,29,30,31)/t18-,19-
PDB

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n/an/a 214n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308091
PNG
(US9649309, Compound UNC2599A)
Show SMILES CCCCNc1ncc(C(=O)NCc2ccc(nc2)-c2ccco2)c(N[C@H]2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C25H32N6O3/c1-2-3-12-26-25-29-16-20(23(31-25)30-18-7-9-19(32)10-8-18)24(33)28-15-17-6-11-21(27-14-17)22-5-4-13-34-22/h4-6,11,13-14,16,18-19,32H,2-3,7-10,12,15H2,1H3,(H,28,33)(H2,26,29,30,31)/t18-,19-
PDB

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n/an/a 165n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308092
PNG
(US9649309, Compound UNC2600A)
Show SMILES CCCCNc1ncc(C(=O)NC2CCN(Cc3ccccc3)CC2)c(N[C@H]2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C27H40N6O2/c1-2-3-15-28-27-29-18-24(25(32-27)30-21-9-11-23(34)12-10-21)26(35)31-22-13-16-33(17-14-22)19-20-7-5-4-6-8-20/h4-8,18,21-23,34H,2-3,9-17,19H2,1H3,(H,31,35)(H2,28,29,30,32)/t21-,23-
PDB

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n/an/a 159n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308093
PNG
(US9649309, Compound UNC2601A)
Show SMILES CCCCNc1ncc(C(=O)NC2CCN(C)CC2)c(N[C@H]2CC[C@H](O)CC2)n1
Show InChI InChI=1S/C21H36N6O2/c1-3-4-11-22-21-23-14-18(20(29)25-16-9-12-27(2)13-10-16)19(26-21)24-15-5-7-17(28)8-6-15/h14-17,28H,3-13H2,1-2H3,(H,25,29)(H2,22,23,24,26)/t15-,17-
PDB

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n/an/a 249n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308310
PNG
(US9649309, Compound UNC4272A)
Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1cc(Nc2ccccc2OC)ncn1
Show InChI InChI=1S/C25H33N7O2/c1-3-4-13-26-25-27-15-19(24(32-25)30-17-9-11-18(33)12-10-17)21-14-23(29-16-28-21)31-20-7-5-6-8-22(20)34-2/h5-8,14-18,33H,3-4,9-13H2,1-2H3,(H,28,29,31)(H2,26,27,30,32)/t17-,18-
PDB

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n/an/a 194n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308311
PNG
(US9649309, Compound UNC4322A)
Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1cc(Nc2cccc(c2)[N+]([O-])=O)ncn1
Show InChI InChI=1S/C24H30N8O3/c1-2-3-11-25-24-26-14-20(23(31-24)30-16-7-9-19(33)10-8-16)21-13-22(28-15-27-21)29-17-5-4-6-18(12-17)32(34)35/h4-6,12-16,19,33H,2-3,7-11H2,1H3,(H,27,28,29)(H2,25,26,30,31)/t16-,19-
PDB

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n/an/a 889n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308312
PNG
(US9649309, Compound UNC4323A)
Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1cc(Nc2cccc(c2)C(C)C)ncn1
Show InChI InChI=1S/C27H37N7O/c1-4-5-13-28-27-29-16-23(26(34-27)33-20-9-11-22(35)12-10-20)24-15-25(31-17-30-24)32-21-8-6-7-19(14-21)18(2)3/h6-8,14-18,20,22,35H,4-5,9-13H2,1-3H3,(H,30,31,32)(H2,28,29,33,34)/t20-,22-
PDB

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n/an/a 619n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308313
PNG
(US9649309, Compound UNC4333A)
Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1cc(Nc2cccc(c2)C(C)(C)C)ncn1
Show InChI InChI=1S/C28H39N7O/c1-5-6-14-29-27-30-17-23(26(35-27)34-20-10-12-22(36)13-11-20)24-16-25(32-18-31-24)33-21-9-7-8-19(15-21)28(2,3)4/h7-9,15-18,20,22,36H,5-6,10-14H2,1-4H3,(H,31,32,33)(H2,29,30,34,35)/t20-,22-
PDB

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n/an/a 867n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308314
PNG
(US9649309, Compound UNC4353A)
Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1cc(Nc2cccc(c2)-c2ccccc2)ncn1
Show InChI InChI=1S/C30H35N7O/c1-2-3-16-31-30-32-19-26(29(37-30)36-23-12-14-25(38)15-13-23)27-18-28(34-20-33-27)35-24-11-7-10-22(17-24)21-8-5-4-6-9-21/h4-11,17-20,23,25,38H,2-3,12-16H2,1H3,(H,33,34,35)(H2,31,32,36,37)/t23-,25-
PDB

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UniChem
US Patent
n/an/a 1.51E+4n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308315
PNG
(US9649309, Compound UNC3664A)
Show SMILES CCCCNc1ncc(c(NC2CCC(O)CC2)n1)-c1ccc(cn1)C1(CC1)N1CCOCC1
Show InChI InChI=1S/C26H38N6O2/c1-2-3-12-27-25-29-18-22(24(31-25)30-20-5-7-21(33)8-6-20)23-9-4-19(17-28-23)26(10-11-26)32-13-15-34-16-14-32/h4,9,17-18,20-21,33H,2-3,5-8,10-16H2,1H3,(H2,27,29,30,31)
PDB

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US Patent
n/an/a 18n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308316
PNG
(US9649309, Compound UNC3665A)
Show SMILES CCCC1(CC1)Nc1ncc(c(NC2CCC(O)CC2)n1)-c1ccccn1
Show InChI InChI=1S/C21H29N5O/c1-2-10-21(11-12-21)26-20-23-14-17(18-5-3-4-13-22-18)19(25-20)24-15-6-8-16(27)9-7-15/h3-5,13-16,27H,2,6-12H2,1H3,(H2,23,24,25,26)
PDB

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US Patent
n/an/a 3.07E+3n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308317
PNG
(US9649309, Compound UNC3666A)
Show SMILES CCCCNc1ncc(c(NC2CCC(O)CC2)n1)-c1ccc(cn1)C1(CCC1)N1CCOCC1
Show InChI InChI=1S/C27H40N6O2/c1-2-3-13-28-26-30-19-23(25(32-26)31-21-6-8-22(34)9-7-21)24-10-5-20(18-29-24)27(11-4-12-27)33-14-16-35-17-15-33/h5,10,18-19,21-22,34H,2-4,6-9,11-17H2,1H3,(H2,28,30,31,32)
PDB

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US Patent
n/an/a 11n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308318
PNG
(US9649309, Compound UNC3667A)
Show SMILES CCCCNc1ncc(c(NC2CCC(O)CC2)n1)-c1ccc(cn1)C1(CCCC1)N1CCOCC1
Show InChI InChI=1S/C28H42N6O2/c1-2-3-14-29-27-31-20-24(26(33-27)32-22-7-9-23(35)10-8-22)25-11-6-21(19-30-25)28(12-4-5-13-28)34-15-17-36-18-16-34/h6,11,19-20,22-23,35H,2-5,7-10,12-18H2,1H3,(H2,29,31,32,33)
PDB

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US Patent
n/an/a 7.40n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308319
PNG
(US9649309, Compound UNC3669A)
Show SMILES CCCCNc1ncc(c(NC2CCC(O)CC2)n1)-c1ccc(cn1)C1(CCC1)N1CCN(C)CC1
Show InChI InChI=1S/C28H43N7O/c1-3-4-14-29-27-31-20-24(26(33-27)32-22-7-9-23(36)10-8-22)25-11-6-21(19-30-25)28(12-5-13-28)35-17-15-34(2)16-18-35/h6,11,19-20,22-23,36H,3-5,7-10,12-18H2,1-2H3,(H2,29,31,32,33)
PDB

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US Patent
n/an/a 7.70n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
Growth arrest-specific protein 6


(Homo sapiens (human))
BDBM308320
PNG
(US9649309, Compound UNC4359A)
Show SMILES CCCCNc1ncc(c(N[C@H]2CC[C@H](O)CC2)n1)-c1ccc(N)cn1
Show InChI InChI=1S/C19H28N6O/c1-2-3-10-21-19-23-12-16(17-9-4-13(20)11-22-17)18(25-19)24-14-5-7-15(26)8-6-14/h4,9,11-12,14-15,26H,2-3,5-8,10,20H2,1H3,(H2,21,23,24,25)/t14-,15-
PDB

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UniChem
US Patent
n/an/a 568n/an/an/an/an/an/a



The University of North Carolina at Chapel Hill

US Patent


Assay Description
Briefly, activity assays were performed in a 384 well, polypropylene microplate in a final volume of 50 μL of 50 mM Hepes, Ph 7.4 containing 10 ...


US Patent US9649309 (2017)

More data for this
Ligand-Target Pair
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