Found 252 Enz. Inhib. hit(s) with Target = 'Acyl-protein thioesterase 1' TargetAcyl-protein thioesterase 1 [I75L,S82A,Q83P,R149H,A150R,S151A](Homo sapiens (Human))
University Of Michigan
University Of Michigan
Affinity DataKi: 180nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
Affinity DataKi: 280nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
Affinity DataKi: 280nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
3D Structure (crystal)Affinity DataKi: 340nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
Affinity DataKi: 370nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
Affinity DataKi: 370nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
Affinity DataKi: 1.20E+3nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
Affinity DataKi: 2.20E+3nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1 [I75L,S82A,Q83P,R149H,A150R,S151A](Homo sapiens (Human))
University Of Michigan
University Of Michigan
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMpH: 6.5Assay Description:Enzymes were diluted to 10 nM in PBS pH 6.5 (adjusted with sodium acetate) supplemented with 0.1 g/L pluronic F127 (Sigma). Varying concentrations of...More data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1(Rattus norvegicus)
Peking University First Hospital
Curated by ChEMBL
Peking University First Hospital
Curated by ChEMBL
Affinity DataKi: 23nMAssay Description:Inhibition of recombinant N-terminal FLAG-tagged FAP (unknown origin) (38 to 760 residues) expressed in HEK293 cells using AMCC as substrate by fluor...More data for this Ligand-Target Pair
Affinity DataKi: 300nMAssay Description:Inhibition of APT1 (unknown origin) by FluPol-ABPP assayMore data for this Ligand-Target Pair
Affinity DataKi: 990nMAssay Description:Inhibition of APT1 (unknown origin) by enzyme kinetic assayMore data for this Ligand-Target Pair
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of APT1 (unknown origin) by FluPol-ABPP assayMore data for this Ligand-Target Pair
Affinity DataIC50: 510nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 1.10E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 1.40E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 2.30E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 2.60E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 2.70E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 3.20E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 3.70E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 3.90E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 4.60E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 6.30E+3nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 1.02E+4nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 1.35E+4nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 1.48E+4nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 1.69E+4nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: 3.36E+4nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
Affinity DataIC50: >5.00E+4nMAssay Description:The enzyme activities were determined by measuring the release of fluorescent 6,8-difluoro-4-methylumbelliferone (DiFMU) by the APT hydrolysis of DiF...More data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1(Rattus norvegicus)
Peking University First Hospital
Curated by ChEMBL
Peking University First Hospital
Curated by ChEMBL
Affinity DataIC50: 1.80E+4nMAssay Description:Inhibition of human FAPMore data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1(Rattus norvegicus)
Peking University First Hospital
Curated by ChEMBL
Peking University First Hospital
Curated by ChEMBL
Affinity DataIC50: 1.00E+5nMAssay Description:Inhibition of human FAPMore data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1(Rattus norvegicus)
Peking University First Hospital
Curated by ChEMBL
Peking University First Hospital
Curated by ChEMBL
Affinity DataIC50: 4.60E+3nMAssay Description:Inhibition of human FAPMore data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1(Rattus norvegicus)
Peking University First Hospital
Curated by ChEMBL
Peking University First Hospital
Curated by ChEMBL
Affinity DataIC50: 2.30E+4nMAssay Description:Inhibition of human FAPMore data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1(Rattus norvegicus)
Peking University First Hospital
Curated by ChEMBL
Peking University First Hospital
Curated by ChEMBL
Affinity DataIC50: 2.70E+3nMAssay Description:Inhibition of human FAPMore data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1(Rattus norvegicus)
Peking University First Hospital
Curated by ChEMBL
Peking University First Hospital
Curated by ChEMBL
Affinity DataIC50: 9.70E+3nMAssay Description:Inhibition of human FAPMore data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1(Rattus norvegicus)
Peking University First Hospital
Curated by ChEMBL
Peking University First Hospital
Curated by ChEMBL
Affinity DataIC50: 7.70E+4nMAssay Description:Inhibition of human FAPMore data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1(Rattus norvegicus)
Peking University First Hospital
Curated by ChEMBL
Peking University First Hospital
Curated by ChEMBL
Affinity DataIC50: 6.40E+3nMAssay Description:Inhibition of human FAPMore data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1(Rattus norvegicus)
Peking University First Hospital
Curated by ChEMBL
Peking University First Hospital
Curated by ChEMBL
Affinity DataIC50: 7.00E+3nMAssay Description:Inhibition of human FAPMore data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1(Rattus norvegicus)
Peking University First Hospital
Curated by ChEMBL
Peking University First Hospital
Curated by ChEMBL
Affinity DataIC50: 1.00E+4nMAssay Description:Inhibition of human FAPMore data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1(Rattus norvegicus)
Peking University First Hospital
Curated by ChEMBL
Peking University First Hospital
Curated by ChEMBL
Affinity DataIC50: 5.50E+4nMAssay Description:Inhibition of human FAPMore data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1(Rattus norvegicus)
Peking University First Hospital
Curated by ChEMBL
Peking University First Hospital
Curated by ChEMBL
Affinity DataIC50: 1.70E+3nMAssay Description:Inhibition of human FAPMore data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1(Rattus norvegicus)
Peking University First Hospital
Curated by ChEMBL
Peking University First Hospital
Curated by ChEMBL
Affinity DataIC50: 5.80E+4nMAssay Description:Inhibition of human FAPMore data for this Ligand-Target Pair
TargetAcyl-protein thioesterase 1(Rattus norvegicus)
Peking University First Hospital
Curated by ChEMBL
Peking University First Hospital
Curated by ChEMBL
Affinity DataIC50: 3.00E+4nMAssay Description:Inhibition of human FAPMore data for this Ligand-Target Pair
