BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 5686 hits Enz. Inhib. hit(s) with Target = 'Baculoviral IAP repeat-containing protein 2'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Estrogen receptor


(Homo sapiens (Human))
BDBM269356
PNG
((E)-3-(4-((6-hydroxy-2- (2-methyl-4- (trifluoromet...)
Show SMILES Cc1cc(ccc1-c1sc2cc(O)ccc2c1Oc1ccc(\C=C\C(O)=O)cc1)C(F)(F)F
Show InChI InChI=1S/C25H17F3O4S/c1-14-12-16(25(26,27)28)5-9-19(14)24-23(20-10-6-17(29)13-21(20)33-24)32-18-7-2-15(3-8-18)4-11-22(30)31/h2-13,29H,1H3,(H,30,31)/b11-4+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 207n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269357
PNG
((E)-3-(4-((2-(2,4- bis(trifluoromethyl) phenyl)-6-...)
Show SMILES OC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccc(cc2C(F)(F)F)C(F)(F)F)cc1
Show InChI InChI=1S/C25H14F6O4S/c26-24(27,28)14-4-8-17(19(11-14)25(29,30)31)23-22(18-9-5-15(32)12-20(18)36-23)35-16-6-1-13(2-7-16)3-10-21(33)34/h1-12,32H,(H,33,34)/b10-3+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 53n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269358
PNG
((E)-3-(4-((2-(4-fluoro- 2-methylphenyl)-6- hydroxy...)
Show SMILES Cc1cc(F)ccc1-c1sc2cc(O)ccc2c1Oc1ccc(\C=C\C(O)=O)cc1
Show InChI InChI=1S/C24H17FO4S/c1-14-12-16(25)5-9-19(14)24-23(20-10-6-17(26)13-21(20)30-24)29-18-7-2-15(3-8-18)4-11-22(27)28/h2-13,26H,1H3,(H,27,28)/b11-4+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 78n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269359
PNG
((E)-3-(4-((2-(2,3- dimethylphenyl)-6- hydroxybenzo...)
Show SMILES Cc1cccc(-c2sc3cc(O)ccc3c2Oc2ccc(\C=C\C(O)=O)cc2)c1C
Show InChI InChI=1S/C25H20O4S/c1-15-4-3-5-20(16(15)2)25-24(21-12-9-18(26)14-22(21)30-25)29-19-10-6-17(7-11-19)8-13-23(27)28/h3-14,26H,1-2H3,(H,27,28)/b13-8+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 151n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269360
PNG
((E)-3-(4-((2-(2,5- dimethylphenyl)-6- hydroxybenzo...)
Show SMILES Cc1ccc(C)c(c1)-c1sc2cc(O)ccc2c1Oc1ccc(\C=C\C(O)=O)cc1
Show InChI InChI=1S/C25H20O4S/c1-15-3-4-16(2)21(13-15)25-24(20-11-8-18(26)14-22(20)30-25)29-19-9-5-17(6-10-19)7-12-23(27)28/h3-14,26H,1-2H3,(H,27,28)/b12-7+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 238n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269361
PNG
((E)-3-(4-((2-(3,5- dimethylisoxazol-4-yl)- 6-hydro...)
Show SMILES Cc1noc(C)c1-c1sc2cc(O)ccc2c1Oc1ccc(\C=C\C(O)=O)cc1
Show InChI InChI=1S/C22H17NO5S/c1-12-20(13(2)28-23-12)22-21(17-9-6-15(24)11-18(17)29-22)27-16-7-3-14(4-8-16)5-10-19(25)26/h3-11,24H,1-2H3,(H,25,26)/b10-5+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 404n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269362
PNG
((E)-3-(4-((6-hydroxy-2- (3-hydroxy-2-methyl- pheny...)
Show SMILES Cc1c(O)cccc1-c1sc2cc(O)ccc2c1Oc1ccc(\C=C\C(O)=O)cc1
Show InChI InChI=1S/C24H18O5S/c1-14-18(3-2-4-20(14)26)24-23(19-11-8-16(25)13-21(19)30-24)29-17-9-5-15(6-10-17)7-12-22(27)28/h2-13,25-26H,1H3,(H,27,28)/b12-7+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 128n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269363
PNG
((E)-3-(4-((2-(4-fluoro- 2-(trifluoromethyl)- pheny...)
Show SMILES OC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccc(F)cc2C(F)(F)F)cc1
Show InChI InChI=1S/C24H14F4O4S/c25-14-4-8-17(19(11-14)24(26,27)28)23-22(18-9-5-15(29)12-20(18)33-23)32-16-6-1-13(2-7-16)3-10-21(30)31/h1-12,29H,(H,30,31)/b10-3+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 12n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269364
PNG
((E)-3-(4-((2-(2- ethylphenyl)-6- hydroxybenzo[b] t...)
Show SMILES CCc1ccccc1-c1sc2cc(O)ccc2c1Oc1ccc(\C=C\C(O)=O)cc1
Show InChI InChI=1S/C25H20O4S/c1-2-17-5-3-4-6-20(17)25-24(21-13-10-18(26)15-22(21)30-25)29-19-11-7-16(8-12-19)9-14-23(27)28/h3-15,26H,2H2,1H3,(H,27,28)/b14-9+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 36n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269365
PNG
((E)-3-(4-((2-(2- acetylphenyl)-6- hydroxybenzo[b] ...)
Show SMILES CC(=O)c1ccccc1-c1sc2cc(O)ccc2c1Oc1ccc(\C=C\C(O)=O)cc1
Show InChI InChI=1S/C25H18O5S/c1-15(26)19-4-2-3-5-20(19)25-24(21-12-9-17(27)14-22(21)31-25)30-18-10-6-16(7-11-18)8-13-23(28)29/h2-14,27H,1H3,(H,28,29)/b13-8+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 218n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269430
PNG
(US10058534, 85)
Show SMILES CC(C)[C@H](N)C(=O)Oc1ccc2c(Oc3ccc(\C=C\C(O)=O)cc3)c(sc2c1)-c1ccccc1C(C)C
Show InChI InChI=1S/C31H31NO5S/c1-18(2)23-7-5-6-8-24(23)30-29(36-21-12-9-20(10-13-21)11-16-27(33)34)25-15-14-22(17-26(25)38-30)37-31(35)28(32)19(3)4/h5-19,28H,32H2,1-4H3,(H,33,34)/b16-11+/t28-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269431
PNG
((E)-3-(4-((2-(2-(sec- butyl)phenyl)-6- hydroxybenz...)
Show SMILES CCC(C)c1ccccc1-c1sc2cc(O)ccc2c1Oc1ccc(\C=C\C(O)=O)cc1
Show InChI InChI=1S/C27H24O4S/c1-3-17(2)21-6-4-5-7-22(21)27-26(23-14-11-19(28)16-24(23)32-27)31-20-12-8-18(9-13-20)10-15-25(29)30/h4-17,28H,3H2,1-2H3,(H,29,30)/b15-10+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269432
PNG
((E)-3-(4-((2-(2- cyclopentylphenyl)-6- hydroxybenz...)
Show SMILES OC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccccc2C2CCCC2)cc1
Show InChI InChI=1S/C28H24O4S/c29-20-12-15-24-25(17-20)33-28(23-8-4-3-7-22(23)19-5-1-2-6-19)27(24)32-21-13-9-18(10-14-21)11-16-26(30)31/h3-4,7-17,19,29H,1-2,5-6H2,(H,30,31)/b16-11+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 14n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269433
PNG
((E)-3-(4-((2-(4-fluoro- 2-(2,2,2- trifluoroethyl)p...)
Show SMILES OC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccc(F)cc2CC(F)(F)F)cc1
Show InChI InChI=1S/C25H16F4O4S/c26-16-4-8-19(15(11-16)13-25(27,28)29)24-23(20-9-5-17(30)12-21(20)34-24)33-18-6-1-14(2-7-18)3-10-22(31)32/h1-12,30H,13H2,(H,31,32)/b10-3+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 13n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269434
PNG
((E)-3-(4-((2-(2- cyclobutylphenyl)-6- hydroxybenzo...)
Show SMILES OC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccccc2C2CCC2)cc1
Show InChI InChI=1S/C27H22O4S/c28-19-11-14-23-24(16-19)32-27(22-7-2-1-6-21(22)18-4-3-5-18)26(23)31-20-12-8-17(9-13-20)10-15-25(29)30/h1-2,6-16,18,28H,3-5H2,(H,29,30)/b15-10+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 19n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269435
PNG
((E)-3-(4-((2-(3-fluoro- 2- (trifluoromethyl) pheny...)
Show SMILES OC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2cccc(F)c2C(F)(F)F)cc1
Show InChI InChI=1S/C24H14F4O4S/c25-18-3-1-2-17(21(18)24(26,27)28)23-22(16-10-7-14(29)12-19(16)33-23)32-15-8-4-13(5-9-15)6-11-20(30)31/h1-12,29H,(H,30,31)/b11-6+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 26n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269436
PNG
((E)-3-(4-((6-hydroxy-2- (6-methoxy-2- (trifluorome...)
Show SMILES COc1ccc(-c2sc3cc(O)ccc3c2Oc2ccc(\C=C\C(O)=O)cc2)c(n1)C(F)(F)F
Show InChI InChI=1S/C24H16F3NO5S/c1-32-19-10-9-17(23(28-19)24(25,26)27)22-21(16-8-5-14(29)12-18(16)34-22)33-15-6-2-13(3-7-15)4-11-20(30)31/h2-12,29H,1H3,(H,30,31)/b11-4+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 23n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269437
PNG
((E)-3-(4-((6-hydroxy-2- (2-(pyrrolidin-1- ylmethyl...)
Show SMILES OC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccccc2CN2CCCC2)cc1
Show InChI InChI=1S/C28H25NO4S/c30-21-10-13-24-25(17-21)34-28(23-6-2-1-5-20(23)18-29-15-3-4-16-29)27(24)33-22-11-7-19(8-12-22)9-14-26(31)32/h1-2,5-14,17,30H,3-4,15-16,18H2,(H,31,32)/b14-9+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 29n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269438
PNG
(3-(4-((6-hydroxy-2-(2- isopropylphenyl)benzo [b]th...)
Show SMILES CC(C)c1ccccc1-c1sc2cc(O)ccc2c1Oc1ccc(CCC(O)=O)cc1
Show InChI InChI=1S/C26H24O4S/c1-16(2)20-5-3-4-6-21(20)26-25(22-13-10-18(27)15-23(22)31-26)30-19-11-7-17(8-12-19)9-14-24(28)29/h3-8,10-13,15-16,27H,9,14H2,1-2H3,(H,28,29)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 72n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269439
PNG
((E)-3-(4-((2-(2- (cyanomethyl)phenyl)- 6- hydroxyb...)
Show SMILES OC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccccc2CC#N)cc1
Show InChI InChI=1S/C25H17NO4S/c26-14-13-17-3-1-2-4-20(17)25-24(21-11-8-18(27)15-22(21)31-25)30-19-9-5-16(6-10-19)7-12-23(28)29/h1-12,15,27H,13H2,(H,28,29)/b12-7+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 86n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269440
PNG
((E)-3-(4-((2-(5-fluoro- 2- (trifluoromethyl) pheny...)
Show SMILES OC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2cc(F)ccc2C(F)(F)F)cc1
Show InChI InChI=1S/C24H14F4O4S/c25-14-4-9-19(24(26,27)28)18(11-14)23-22(17-8-5-15(29)12-20(17)33-23)32-16-6-1-13(2-7-16)3-10-21(30)31/h1-12,29H,(H,30,31)/b10-3+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 109n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269441
PNG
((E)-3-(4-((6-hydroxy-2- (2-((2-methyl-2H- tetrazol...)
Show SMILES Cn1nnc(Cc2ccccc2-c2sc3cc(O)ccc3c2Oc2ccc(\C=C\C(O)=O)cc2)n1
Show InChI InChI=1S/C26H20N4O4S/c1-30-28-23(27-29-30)14-17-4-2-3-5-20(17)26-25(21-12-9-18(31)15-22(21)35-26)34-19-10-6-16(7-11-19)8-13-24(32)33/h2-13,15,31H,14H2,1H3,(H,32,33)/b13-8+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 212n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269442
PNG
((E)-3-(4-((2-(2- (azetidin-1- ylmethyl)phenyl)-6- ...)
Show SMILES OC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccccc2CN2CCC2)cc1
Show InChI InChI=1S/C27H23NO4S/c29-20-9-12-23-24(16-20)33-27(22-5-2-1-4-19(22)17-28-14-3-15-28)26(23)32-21-10-6-18(7-11-21)8-13-25(30)31/h1-2,4-13,16,29H,3,14-15,17H2,(H,30,31)/b13-8+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 292n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269443
PNG
((E)-3-(4-((6-hydroxy-2- (3- isopropylphenyl) benzo...)
Show SMILES CC(C)c1cccc(c1)-c1sc2cc(O)ccc2c1Oc1ccc(\C=C\C(O)=O)cc1
Show InChI InChI=1S/C26H22O4S/c1-16(2)18-4-3-5-19(14-18)26-25(22-12-9-20(27)15-23(22)31-26)30-21-10-6-17(7-11-21)8-13-24(28)29/h3-16,27H,1-2H3,(H,28,29)/b13-8+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 382n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269444
PNG
((E)-3-(4-((2-(4-fluoro- 2-((2-oxopyrrolidin-1- yl)...)
Show SMILES OC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccc(F)cc2CN2CCCC2=O)cc1
Show InChI InChI=1S/C28H22FNO5S/c29-19-6-10-22(18(14-19)16-30-13-1-2-25(30)32)28-27(23-11-7-20(31)15-24(23)36-28)35-21-8-3-17(4-9-21)5-12-26(33)34/h3-12,14-15,31H,1-2,13,16H2,(H,33,34)/b12-5+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 544n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269366
PNG
((E)-3-(4-((2-(2-(tert- butyl)phenyl)-6- hydroxyben...)
Show SMILES CC(C)(C)c1ccccc1-c1sc2cc(O)ccc2c1Oc1ccc(\C=C\C(O)=O)cc1
Show InChI InChI=1S/C27H24O4S/c1-27(2,3)22-7-5-4-6-20(22)26-25(21-14-11-18(28)16-23(21)32-26)31-19-12-8-17(9-13-19)10-15-24(29)30/h4-16,28H,1-3H3,(H,29,30)/b15-10+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 36n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269367
PNG
((E)-3-(4-((6-hydroxy-2- (2-nitrophenyl)- benzo[b]t...)
Show SMILES OC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccccc2[N+]([O-])=O)cc1
Show InChI InChI=1S/C23H15NO6S/c25-15-8-11-18-20(13-15)31-23(17-3-1-2-4-19(17)24(28)29)22(18)30-16-9-5-14(6-10-16)7-12-21(26)27/h1-13,25H,(H,26,27)/b12-7+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 313n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269368
PNG
((E)-3-(4-((2-(4-(tert- butyl)phenyl)-6- hydroxyben...)
Show SMILES CC(C)(C)c1ccc(cc1)-c1sc2cc(O)ccc2c1Oc1ccc(\C=C\C(O)=O)cc1
Show InChI InChI=1S/C27H24O4S/c1-27(2,3)19-9-7-18(8-10-19)26-25(22-14-11-20(28)16-23(22)32-26)31-21-12-4-17(5-13-21)6-15-24(29)30/h4-16,28H,1-3H3,(H,29,30)/b15-6+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 853n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269369
PNG
((E)-3-(4-((2-(3,5- dimethylphenyl)-6- hydroxybenzo...)
Show SMILES Cc1cc(C)cc(c1)-c1sc2cc(O)ccc2c1Oc1ccc(\C=C\C(O)=O)cc1
Show InChI InChI=1S/C25H20O4S/c1-15-11-16(2)13-18(12-15)25-24(21-9-6-19(26)14-22(21)30-25)29-20-7-3-17(4-8-20)5-10-23(27)28/h3-14,26H,1-2H3,(H,27,28)/b10-5+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 748n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269370
PNG
((E)-3-(4-((6-hydroxy-2- (2-isocyanophenyl)- benzo[...)
Show SMILES OC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccccc2[N+]#[C-])cc1
Show InChI InChI=1S/C24H15NO4S/c1-25-20-5-3-2-4-18(20)24-23(19-12-9-16(26)14-21(19)30-24)29-17-10-6-15(7-11-17)8-13-22(27)28/h2-14,26H,(H,27,28)/b13-8+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.58E+3n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269371
PNG
((S,E)-3-(4-((6-hydroxy- 2-(2-(1- hydroxyethyl)phen...)
Show SMILES C[C@H](O)c1ccccc1-c1sc2cc(O)ccc2c1Oc1ccc(\C=C\C(O)=O)cc1
Show InChI InChI=1S/C25H20O5S/c1-15(26)19-4-2-3-5-20(19)25-24(21-12-9-17(27)14-22(21)31-25)30-18-10-6-16(7-11-18)8-13-23(28)29/h2-15,26-27H,1H3,(H,28,29)/b13-8+/t15-/m0/s1
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 179n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269372
PNG
(US10058534, 26)
Show SMILES COc1ccc(cc1)-c1sc2cc(O)ccc2c1Oc1ccc(\C=C\C(O)=O)cc1
Show InChI InChI=1S/C24H18O5S/c1-28-18-10-5-16(6-11-18)24-23(20-12-7-17(25)14-21(20)30-24)29-19-8-2-15(3-9-19)4-13-22(26)27/h2-14,25H,1H3,(H,26,27)/b13-4+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 647n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269373
PNG
(US10058534, 27)
Show SMILES OC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccc(cc2)C(F)F)cc1
Show InChI InChI=1S/C24H16F2O4S/c25-24(26)16-6-4-15(5-7-16)23-22(19-11-8-17(27)13-20(19)31-23)30-18-9-1-14(2-10-18)3-12-21(28)29/h1-13,24,27H,(H,28,29)/b12-3+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.97E+3n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269374
PNG
(US10058534, 28)
Show SMILES C\C(=C/c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccc(O)cc2)cc1)C(O)=O
Show InChI InChI=1S/C24H18O5S/c1-14(24(27)28)12-15-2-9-19(10-3-15)29-22-20-11-8-18(26)13-21(20)30-23(22)16-4-6-17(25)7-5-16/h2-13,25-26H,1H3,(H,27,28)/b14-12+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 886n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269375
PNG
(US10058534, 29)
Show SMILES OC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccc(O)cc2)cn1
Show InChI InChI=1S/C22H15NO5S/c24-15-5-1-13(2-6-15)22-21(18-9-7-16(25)11-19(18)29-22)28-17-8-3-14(23-12-17)4-10-20(26)27/h1-12,24-25H,(H,26,27)/b10-4+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.75E+3n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269376
PNG
(US10058534, 30)
Show SMILES COc1ccc2c(Oc3ccc(\C=C\C(=O)OC(C)(C)C)cc3)csc2c1
Show InChI InChI=1S/C22H22O4S/c1-22(2,3)26-21(23)12-7-15-5-8-16(9-6-15)25-19-14-27-20-13-17(24-4)10-11-18(19)20/h5-14H,1-4H3/b12-7+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.40E+3n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269377
PNG
(US10058534, 31)
Show SMILES Oc1ccc(cc1)-c1sc2cc(O)ccc2c1Oc1ccc(\C=C\C(=O)NCCC(F)(F)F)cc1
Show InChI InChI=1S/C26H20F3NO4S/c27-26(28,29)13-14-30-23(33)12-3-16-1-9-20(10-2-16)34-24-21-11-8-19(32)15-22(21)35-25(24)17-4-6-18(31)7-5-17/h1-12,15,31-32H,13-14H2,(H,30,33)/b12-3+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 10n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269378
PNG
(US10058534, 32)
Show SMILES COC(=O)\C=C\c1ccc(Oc2c(sc3cc(OC)ccc23)-c2ccccc2C(C)C)cc1
Show InChI InChI=1S/C28H26O4S/c1-18(2)22-7-5-6-8-23(22)28-27(24-15-14-21(30-3)17-25(24)33-28)32-20-12-9-19(10-13-20)11-16-26(29)31-4/h5-18H,1-4H3/b16-11+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 15n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269379
PNG
((E)-3-(4-((2-(4- fluorophenyl)-6- hydroxybenzo[b] ...)
Show SMILES Oc1ccc2c(Oc3ccc(\C=C\C(=O)NCCC(F)(F)F)cc3)c(sc2c1)-c1ccc(F)cc1
Show InChI InChI=1S/C26H19F4NO3S/c27-18-6-4-17(5-7-18)25-24(21-11-8-19(32)15-22(21)35-25)34-20-9-1-16(2-10-20)3-12-23(33)31-14-13-26(28,29)30/h1-12,15,32H,13-14H2,(H,31,33)/b12-3+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 73n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269380
PNG
((E)-ethyl 3-(4-((6- hydroxy-2-(4- hydroxyphenyl)be...)
Show SMILES CCOC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccc(O)cc2)cc1C
Show InChI InChI=1S/C26H22O5S/c1-3-30-24(29)13-7-17-6-11-21(14-16(17)2)31-25-22-12-10-20(28)15-23(22)32-26(25)18-4-8-19(27)9-5-18/h4-15,27-28H,3H2,1-2H3/b13-7+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 48n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269381
PNG
((E)-ethyl 3-(4-((6- hydroxy-2-(4- hydroxyphenyl)be...)
Show SMILES CCOC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccc(O)cc2)c(C)c1
Show InChI InChI=1S/C26H22O5S/c1-3-30-24(29)13-5-17-4-12-22(16(2)14-17)31-25-21-11-10-20(28)15-23(21)32-26(25)18-6-8-19(27)9-7-18/h4-15,27-28H,3H2,1-2H3/b13-5+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 103n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269382
PNG
((E)-methyl 3-(4-((2-(4- fluorophenyl)-6- hydroxybe...)
Show SMILES COC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccc(F)cc2)cc1
Show InChI InChI=1S/C24H17FO4S/c1-28-22(27)13-4-15-2-10-19(11-3-15)29-23-20-12-9-18(26)14-21(20)30-24(23)16-5-7-17(25)8-6-16/h2-14,26H,1H3/b13-4+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 137n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269383
PNG
((E)-methyl 3-(4-((5,7- difluoro-6-hydroxy-2- (4-hy...)
Show SMILES COC(=O)\C=C\c1ccc(Oc2c(sc3c(F)c(O)c(F)cc23)-c2ccc(O)cc2)cc1
Show InChI InChI=1S/C24H16F2O5S/c1-30-19(28)11-4-13-2-9-16(10-3-13)31-22-17-12-18(25)21(29)20(26)24(17)32-23(22)14-5-7-15(27)8-6-14/h2-12,27,29H,1H3/b11-4+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 41n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269384
PNG
((E)-3-(4-((5,7-difluoro- 6-hydroxy-2-(4- hydroxyph...)
Show SMILES OC(=O)\C=C\c1ccc(Oc2c(sc3c(F)c(O)c(F)cc23)-c2ccc(O)cc2)cc1
Show InChI InChI=1S/C23H14F2O5S/c24-17-11-16-21(30-15-8-1-12(2-9-15)3-10-18(27)28)22(13-4-6-14(26)7-5-13)31-23(16)19(25)20(17)29/h1-11,26,29H,(H,27,28)/b10-3+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 152n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269385
PNG
((E)-3-(4-((7-fluoro-6- hydroxy-2-(4- hydroxyphenyl...)
Show SMILES OC(=O)\C=C\c1ccc(Oc2c(sc3c(F)c(O)ccc23)-c2ccc(O)cc2)cc1
Show InChI InChI=1S/C23H15FO5S/c24-20-18(26)11-10-17-21(22(30-23(17)20)14-4-6-15(25)7-5-14)29-16-8-1-13(2-9-16)3-12-19(27)28/h1-12,25-26H,(H,27,28)/b12-3+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 653n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269386
PNG
((E)-3-(4-((2-(3-fluoro- 4-hydroxyphenyl)-6- hydrox...)
Show SMILES OC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccc(O)c(F)c2)cc1
Show InChI InChI=1S/C23H15FO5S/c24-18-11-14(4-9-19(18)26)23-22(17-8-5-15(25)12-20(17)30-23)29-16-6-1-13(2-7-16)3-10-21(27)28/h1-12,25-26H,(H,27,28)/b10-3+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 424n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269387
PNG
((E)-methyl 3-(4-((6- hydroxy-2-(4-hydroxy- 3-methy...)
Show SMILES COC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccc(O)c(C)c2)cc1
Show InChI InChI=1S/C25H20O5S/c1-15-13-17(6-11-21(15)27)25-24(20-10-7-18(26)14-22(20)31-25)30-19-8-3-16(4-9-19)5-12-23(28)29-2/h3-14,26-27H,1-2H3/b12-5+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.00E+4n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269388
PNG
((E)-ethyl 3-(4-((6- hydroxy-2-(4- hydroxyphenyl)be...)
Show SMILES CCOC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccc(O)cc2)cc1OC
Show InChI InChI=1S/C26H22O6S/c1-3-31-24(29)13-7-16-6-11-20(15-22(16)30-2)32-25-21-12-10-19(28)14-23(21)33-26(25)17-4-8-18(27)9-5-17/h4-15,27-28H,3H2,1-2H3/b13-7+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.00E+4n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269389
PNG
((E)-methyl 3-(4-((6- hydroxy-2- phenylbenzo[b]thio...)
Show SMILES COC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccccc2)cc1
Show InChI InChI=1S/C24H18O4S/c1-27-22(26)14-9-16-7-11-19(12-8-16)28-23-20-13-10-18(25)15-21(20)29-24(23)17-5-3-2-4-6-17/h2-15,25H,1H3/b14-9+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.00E+4n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Estrogen receptor


(Homo sapiens (Human))
BDBM269390
PNG
(US10058534, 45)
Show SMILES COC(=O)\C=C\c1ccc(Oc2c(sc3cc(O)ccc23)-c2ccccc2C(C)C)cc1
Show InChI InChI=1S/C27H24O4S/c1-17(2)21-6-4-5-7-22(21)27-26(23-14-11-19(28)16-24(23)32-27)31-20-12-8-18(9-13-20)10-15-25(29)30-3/h4-17,28H,1-3H3/b15-10+
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 23n/an/an/an/a5.137



Novartis AG

US Patent


Assay Description
The ER transcription assay is a reporter assay that is based on the ability of ER to induce transcription from a luciferase reporter gene containing ...


US Patent US10058534 (2018)

More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 5686 total )  |  Next  |  Last  >>
Jump to: