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Compile Data Set for Download or QSAR

Found 370 hits Enz. Inhib. hit(s) with Target = 'Carboxypeptidase B2 isoform A'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173886
PNG
(US9688645, 1-1)
Show SMILES CC(C)[C@H]1COCCCCOc2ccc(C[C@@H](NC(=O)N[C@@H](CCCCN)C(O)=O)C(=O)N1)cc2
Show InChI InChI=1S/C25H40N4O6/c1-17(2)22-16-34-13-5-6-14-35-19-10-8-18(9-11-19)15-21(23(30)27-22)29-25(33)28-20(24(31)32)7-3-4-12-26/h8-11,17,20-22H,3-7,12-16,26H2,1-2H3,(H,27,30)(H,31,32)(H2,28,29,33)/t20-,21+,22+/m0/s1
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n/an/a 6n/an/an/an/a7.425



Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173931
PNG
(US9688645, 8-3)
Show SMILES CC(C)[C@H]1COCCCCOc2ccc(C[C@@H](NS(=O)(=O)N[C@@H](CCCCN)C(O)=O)C(=O)N1)cc2
Show InChI InChI=1S/C24H40N4O7S/c1-17(2)22-16-34-13-5-6-14-35-19-10-8-18(9-11-19)15-21(23(29)26-22)28-36(32,33)27-20(24(30)31)7-3-4-12-25/h8-11,17,20-22,27-28H,3-7,12-16,25H2,1-2H3,(H,26,29)(H,30,31)/t20-,21+,22+/m0/s1
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n/an/a 59n/an/an/an/a7.425



Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173894
PNG
(US9688645, 1-3)
Show SMILES CC1(C)COCCCCOc2ccc(C[C@@H](NC(=O)N[C@@H](CCCCN)C(O)=O)C(=O)N1)cc2
Show InChI InChI=1S/C24H38N4O6/c1-24(2)16-33-13-5-6-14-34-18-10-8-17(9-11-18)15-20(21(29)28-24)27-23(32)26-19(22(30)31)7-3-4-12-25/h8-11,19-20H,3-7,12-16,25H2,1-2H3,(H,28,29)(H,30,31)(H2,26,27,32)/t19-,20+/m0/s1
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n/an/a 269n/an/an/an/a7.425



Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173897
PNG
(US9688645, 1-4)
Show SMILES NCCCC[C@H](NC(=O)N[C@@H]1Cc2ccc(OCCCCOC[C@@H](NC1=O)c1ccccc1)cc2)C(O)=O
Show InChI InChI=1S/C28H38N4O6/c29-15-5-4-10-23(27(34)35)31-28(36)32-24-18-20-11-13-22(14-12-20)38-17-7-6-16-37-19-25(30-26(24)33)21-8-2-1-3-9-21/h1-3,8-9,11-14,23-25H,4-7,10,15-19,29H2,(H,30,33)(H,34,35)(H2,31,32,36)/t23-,24+,25+/m0/s1
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n/an/a 71n/an/an/an/a7.425



Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173898
PNG
(US9688645, 1-5)
Show SMILES NCCCC[C@H](NC(=O)N[C@@H]1Cc2ccc(OCCCCOC[C@H](Cc3ccccc3)NC1=O)cc2)C(O)=O
Show InChI InChI=1S/C29H40N4O6/c30-15-5-4-10-25(28(35)36)32-29(37)33-26-19-22-11-13-24(14-12-22)39-17-7-6-16-38-20-23(31-27(26)34)18-21-8-2-1-3-9-21/h1-3,8-9,11-14,23,25-26H,4-7,10,15-20,30H2,(H,31,34)(H,35,36)(H2,32,33,37)/t23-,25-,26+/m0/s1
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Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173899
PNG
(US9688645, 1-6)
Show SMILES NCCCC[C@H](NC(=O)N[C@@H]1Cc2ccc(OCCCCOC[C@@H](NC1=O)C1CCCCC1)cc2)C(O)=O
Show InChI InChI=1S/C28H44N4O6/c29-15-5-4-10-23(27(34)35)31-28(36)32-24-18-20-11-13-22(14-12-20)38-17-7-6-16-37-19-25(30-26(24)33)21-8-2-1-3-9-21/h11-14,21,23-25H,1-10,15-19,29H2,(H,30,33)(H,34,35)(H2,31,32,36)/t23-,24+,25+/m0/s1
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Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173900
PNG
(US9688645, 1-7)
Show SMILES CCC[C@H]1COCCCCOc2ccc(C[C@@H](NC(=O)N[C@@H](CCCCN)C(O)=O)C(=O)N1)cc2
Show InChI InChI=1S/C25H40N4O6/c1-2-7-19-17-34-14-5-6-15-35-20-11-9-18(10-12-20)16-22(23(30)27-19)29-25(33)28-21(24(31)32)8-3-4-13-26/h9-12,19,21-22H,2-8,13-17,26H2,1H3,(H,27,30)(H,31,32)(H2,28,29,33)/t19-,21-,22+/m0/s1
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Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173902
PNG
(US9688645, 1-8)
Show SMILES C[C@H]1COCCCCOc2ccc(C[C@@H](NC(=O)N[C@@H](CCCCN)C(O)=O)C(=O)N1)cc2
Show InChI InChI=1S/C23H36N4O6/c1-16-15-32-12-4-5-13-33-18-9-7-17(8-10-18)14-20(21(28)25-16)27-23(31)26-19(22(29)30)6-2-3-11-24/h7-10,16,19-20H,2-6,11-15,24H2,1H3,(H,25,28)(H,29,30)(H2,26,27,31)/t16-,19-,20+/m0/s1
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Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173903
PNG
(US9688645, 1-9)
Show SMILES CC(C)(C)[C@H]1COCCCCOc2ccc(C[C@@H](NC(=O)N[C@@H](CCCCN)C(O)=O)C(=O)N1)cc2
Show InChI InChI=1S/C26H42N4O6/c1-26(2,3)22-17-35-14-6-7-15-36-19-11-9-18(10-12-19)16-21(23(31)30-22)29-25(34)28-20(24(32)33)8-4-5-13-27/h9-12,20-22H,4-8,13-17,27H2,1-3H3,(H,30,31)(H,32,33)(H2,28,29,34)/t20-,21+,22+/m0/s1
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Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173904
PNG
(US9688645, 2-1)
Show SMILES CC(C)[C@H]1COCCCCCCCCOc2ccc(C[C@@H](NC(=O)N[C@@H](CCCCN)C(O)=O)C(=O)N1)cc2
Show InChI InChI=1S/C29H48N4O6/c1-21(2)26-20-38-17-9-5-3-4-6-10-18-39-23-14-12-22(13-15-23)19-25(27(34)31-26)33-29(37)32-24(28(35)36)11-7-8-16-30/h12-15,21,24-26H,3-11,16-20,30H2,1-2H3,(H,31,34)(H,35,36)(H2,32,33,37)/t24-,25+,26+/m0/s1
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Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173906
PNG
(US9688645, 3-1)
Show SMILES CC(C)[C@H]1COC\C=C\COc2ccc(C[C@@H](NC(=O)N[C@@H](CCCCN)C(O)=O)C(=O)N1)cc2
Show InChI InChI=1S/C25H38N4O6/c1-17(2)22-16-34-13-5-6-14-35-19-10-8-18(9-11-19)15-21(23(30)27-22)29-25(33)28-20(24(31)32)7-3-4-12-26/h5-6,8-11,17,20-22H,3-4,7,12-16,26H2,1-2H3,(H,27,30)(H,31,32)(H2,28,29,33)/b6-5+/t20-,21+,22+/m0/s1
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Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173908
PNG
(US9688645, 4-1)
Show SMILES NCCCCC(NC(=O)N[C@@H]1CCCCCCCCOCCNC1=O)C(O)=O
Show InChI InChI=1S/C19H36N4O5/c20-11-7-6-10-16(18(25)26)23-19(27)22-15-9-5-3-1-2-4-8-13-28-14-12-21-17(15)24/h15-16H,1-14,20H2,(H,21,24)(H,25,26)(H2,22,23,27)/t15-,16?/m1/s1
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Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173911
PNG
(US9688645, 5-1)
Show SMILES CC(C)[C@H]1COCCCCOc2ccc(C[C@@H](NC(=O)N[C@@H](CS(=O)(=O)CCN)C(O)=O)C(=O)N1)cc2
Show InChI InChI=1S/C24H38N4O8S/c1-16(2)20-14-35-10-3-4-11-36-18-7-5-17(6-8-18)13-19(22(29)26-20)27-24(32)28-21(23(30)31)15-37(33,34)12-9-25/h5-8,16,19-21H,3-4,9-15,25H2,1-2H3,(H,26,29)(H,30,31)(H2,27,28,32)/t19-,20-,21+/m1/s1
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Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173918
PNG
(US9688645, 5-2)
Show SMILES CC(C)[C@H]1COCCCCOc2ccc(C[C@@H](NC(=O)N[C@@H](Cc3ccc(N)nc3)C(O)=O)C(=O)N1)cc2
Show InChI InChI=1S/C27H37N5O6/c1-17(2)23-16-37-11-3-4-12-38-20-8-5-18(6-9-20)13-21(25(33)30-23)31-27(36)32-22(26(34)35)14-19-7-10-24(28)29-15-19/h5-10,15,17,21-23H,3-4,11-14,16H2,1-2H3,(H2,28,29)(H,30,33)(H,34,35)(H2,31,32,36)/t21-,22+,23-/m1/s1
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US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173920
PNG
(US9688645, 5-3)
Show SMILES Nc1ccc(C[C@H](NC(=O)N[C@@H]2Cc3ccc(OCCCCOC[C@@H](NC2=O)C2CC2)cc3)C(O)=O)cn1
Show InChI InChI=1S/C27H35N5O6/c28-24-10-5-18(15-29-24)14-22(26(34)35)32-27(36)31-21-13-17-3-8-20(9-4-17)38-12-2-1-11-37-16-23(19-6-7-19)30-25(21)33/h3-5,8-10,15,19,21-23H,1-2,6-7,11-14,16H2,(H2,28,29)(H,30,33)(H,34,35)(H2,31,32,36)/t21-,22+,23-/m1/s1
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US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173921
PNG
(US9688645, 6-1)
Show SMILES CC(C)[C@H]1COCCCCC2=CC(C[C@@H](NC(=O)N[C@@H](Cc3ccc(N)nc3)C(O)=O)C(=O)N1)=CC2
Show InChI InChI=1S/C26H37N5O5/c1-16(2)22-15-36-10-4-3-5-17-6-7-18(11-17)12-20(24(32)29-22)30-26(35)31-21(25(33)34)13-19-8-9-23(27)28-14-19/h7-9,11,14,16,20-22H,3-6,10,12-13,15H2,1-2H3,(H2,27,28)(H,29,32)(H,33,34)(H2,30,31,35)/t20-,21+,22-/m1/s1
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US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173922
PNG
(US9688645, 6-2)
Show SMILES CC(C)[C@H]1COCCCCc2ccc(C[C@@H](NC(=O)N[C@@H](Cc3ccc(N)nc3)C(O)=O)C(=O)N1)cc2
Show InChI InChI=1S/C27H37N5O5/c1-17(2)23-16-37-12-4-3-5-18-6-8-19(9-7-18)13-21(25(33)30-23)31-27(36)32-22(26(34)35)14-20-10-11-24(28)29-15-20/h6-11,15,17,21-23H,3-5,12-14,16H2,1-2H3,(H2,28,29)(H,30,33)(H,34,35)(H2,31,32,36)/t21-,22+,23-/m1/s1
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US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173923
PNG
(US9688645, 6-3)
Show SMILES CC(C)[C@H]1COCCCCOc2ccc(C[C@@H](NC(=O)N[C@@H](Cc3ccc(N)nc3)C(O)=O)C(=O)N1)cc2F
Show InChI InChI=1S/C27H36FN5O6/c1-16(2)22-15-38-9-3-4-10-39-23-7-5-17(11-19(23)28)12-20(25(34)31-22)32-27(37)33-21(26(35)36)13-18-6-8-24(29)30-14-18/h5-8,11,14,16,20-22H,3-4,9-10,12-13,15H2,1-2H3,(H2,29,30)(H,31,34)(H,35,36)(H2,32,33,37)/t20-,21+,22-/m1/s1
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n/an/a 12n/an/an/an/a7.425



Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173924
PNG
(US9688645, 6-4)
Show SMILES CC(C)[C@H]1COCCCCOC[C@@H](NC(=O)N[C@H](Cc2ccc(N)nc2)C(O)=O)C(=O)N1
Show InChI InChI=1S/C21H33N5O6/c1-13(2)16-11-31-7-3-4-8-32-12-17(19(27)24-16)26-21(30)25-15(20(28)29)9-14-5-6-18(22)23-10-14/h5-6,10,13,15-17H,3-4,7-9,11-12H2,1-2H3,(H2,22,23)(H,24,27)(H,28,29)(H2,25,26,30)/t15-,16-,17-/m1/s1
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n/an/a 55n/an/an/an/a7.425



Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173932
PNG
(US9688645, 6-6)
Show SMILES CC(C)[C@H]1COCCCCOC[C@@H](NC(=O)N[C@H](CCCCN)C(O)=O)C(=O)N1
Show InChI InChI=1S/C19H36N4O6/c1-13(2)15-11-28-9-5-6-10-29-12-16(17(24)21-15)23-19(27)22-14(18(25)26)7-3-4-8-20/h13-16H,3-12,20H2,1-2H3,(H,21,24)(H,25,26)(H2,22,23,27)/t14-,15-,16-/m1/s1
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n/an/a 53n/an/an/an/a7.425



Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173926
PNG
(US9688645, 7-1)
Show SMILES CC(C)[C@H]1COCCC(=O)Nc2ccc(C[C@@H](NC(=O)N[C@@H](CCCCN)C(O)=O)C(=O)N1)cc2
Show InChI InChI=1S/C24H37N5O6/c1-15(2)20-14-35-12-10-21(30)26-17-8-6-16(7-9-17)13-19(22(31)27-20)29-24(34)28-18(23(32)33)5-3-4-11-25/h6-9,15,18-20H,3-5,10-14,25H2,1-2H3,(H,26,30)(H,27,31)(H,32,33)(H2,28,29,34)/t18-,19+,20+/m0/s1
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n/an/a 22n/an/an/an/a7.425



Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173928
PNG
(US9688645, 7-4)
Show SMILES CC(C)[C@H]1COCCNC(=O)c2ccc(C[C@@H](NC(=O)N[C@@H](Cc3ccc(N)nc3)C(O)=O)C(=O)N1)cc2
Show InChI InChI=1S/C26H34N6O6/c1-15(2)21-14-38-10-9-28-23(33)18-6-3-16(4-7-18)11-19(24(34)30-21)31-26(37)32-20(25(35)36)12-17-5-8-22(27)29-13-17/h3-8,13,15,19-21H,9-12,14H2,1-2H3,(H2,27,29)(H,28,33)(H,30,34)(H,35,36)(H2,31,32,37)/t19-,20+,21-/m1/s1
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n/an/a 40n/an/an/an/a7.425



Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173929
PNG
(US9688645, 8-1)
Show SMILES CC(C)[C@H]1COCC(O)C(O)COc2ccc(C[C@@H](NC(=O)N[C@@H](CCCCN)C(O)=O)C(=O)N1)cc2
Show InChI InChI=1S/C25H40N4O8/c1-15(2)20-12-36-13-21(30)22(31)14-37-17-8-6-16(7-9-17)11-19(23(32)27-20)29-25(35)28-18(24(33)34)5-3-4-10-26/h6-9,15,18-22,30-31H,3-5,10-14,26H2,1-2H3,(H,27,32)(H,33,34)(H2,28,29,35)/t18-,19+,20+,21?,22?/m0/s1
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n/an/a 23n/an/an/an/a7.425



Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173930
PNG
(US9688645, 8-2)
Show SMILES CC(C)[C@H]1COCC(O)CCOc2ccc(C[C@@H](NC(=O)N[C@@H](CCCCN)C(O)=O)C(=O)N1)cc2
Show InChI InChI=1S/C25H40N4O7/c1-16(2)22-15-35-14-18(30)10-12-36-19-8-6-17(7-9-19)13-21(23(31)27-22)29-25(34)28-20(24(32)33)5-3-4-11-26/h6-9,16,18,20-22,30H,3-5,10-15,26H2,1-2H3,(H,27,31)(H,32,33)(H2,28,29,34)/t18?,20-,21+,22+/m0/s1
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n/an/a 33n/an/an/an/a7.425



Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM173893
PNG
(US9688645, 1-2)
Show SMILES NCCCC[C@H](NC(=O)N[C@@H]1Cc2ccc(OCCCCOCCNC1=O)cc2)C(O)=O
Show InChI InChI=1S/C22H34N4O6/c23-10-2-1-5-18(21(28)29)25-22(30)26-19-15-16-6-8-17(9-7-16)32-13-4-3-12-31-14-11-24-20(19)27/h6-9,18-19H,1-5,10-15,23H2,(H,24,27)(H,28,29)(H2,25,26,30)/t18-,19+/m0/s1
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n/an/a 9.04E+3n/an/an/an/a7.425



Sanofi

US Patent


Assay Description
The prepared substances were tested for TAFIa inhibition using the Actichrome plasma TAFI Activity Kit from American Diagnostica (Pr. No. 874). This ...


US Patent US9688645 (2017)


BindingDB Entry DOI: 10.7270/Q2PV6HJ3
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50305346
PNG
((S)-2-(2-aminoethoxy)-3-(1-phenyl-1H-imidazol-4-yl...)
Show SMILES NCCO[C@@H](Cc1cn(cn1)-c1ccccc1)C(O)=O
Show InChI InChI=1S/C14H17N3O3/c15-6-7-20-13(14(18)19)8-11-9-17(10-16-11)12-4-2-1-3-5-12/h1-5,9-10,13H,6-8,15H2,(H,18,19)/t13-/m0/s1
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3.5n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins


Bioorg Med Chem Lett 20: 92-6 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.029
BindingDB Entry DOI: 10.7270/Q2J1038R
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50201438
PNG
((+/-)-5-guanidino-2-(mercaptomethyl)pentanoic acid...)
Show SMILES NC(N)=NCCCC(CS)C(O)=O
Show InChI InChI=1S/C7H15N3O2S/c8-7(9)10-3-1-2-5(4-13)6(11)12/h5,13H,1-4H2,(H,11,12)(H4,8,9,10)
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4n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of human TAFIa


J Med Chem 50: 6095-103 (2007)


Article DOI: 10.1021/jm0702433
BindingDB Entry DOI: 10.7270/Q2T153CG
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50305347
PNG
((S)-2-(2-aminoethoxy)-3-(1-(4-tert-butylphenyl)-1H...)
Show SMILES CC(C)(C)c1ccc(cc1)-n1cnc(C[C@H](OCCN)C(O)=O)c1
Show InChI InChI=1S/C18H25N3O3/c1-18(2,3)13-4-6-15(7-5-13)21-11-14(20-12-21)10-16(17(22)23)24-9-8-19/h4-7,11-12,16H,8-10,19H2,1-3H3,(H,22,23)/t16-/m0/s1
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5.70n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins


Bioorg Med Chem Lett 20: 92-6 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.029
BindingDB Entry DOI: 10.7270/Q2J1038R
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50305351
PNG
((S)-2-((R)-1-aminopropan-2-yloxy)-3-(1-(pyridin-2-...)
Show SMILES C[C@H](CN)O[C@@H](Cc1cn(cn1)-c1ccccn1)C(O)=O
Show InChI InChI=1S/C14H18N4O3/c1-10(7-15)21-12(14(19)20)6-11-8-18(9-17-11)13-4-2-3-5-16-13/h2-5,8-10,12H,6-7,15H2,1H3,(H,19,20)/t10-,12+/m1/s1
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5.80n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins


Bioorg Med Chem Lett 20: 92-6 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.029
BindingDB Entry DOI: 10.7270/Q2J1038R
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50305345
PNG
((S)-2-(2-aminoethoxy)-3-(1-propyl-1H-imidazol-4-yl...)
Show SMILES CCCn1cnc(C[C@H](OCCN)C(O)=O)c1
Show InChI InChI=1S/C11H19N3O3/c1-2-4-14-7-9(13-8-14)6-10(11(15)16)17-5-3-12/h7-8,10H,2-6,12H2,1H3,(H,15,16)/t10-/m0/s1
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6.70n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins


Bioorg Med Chem Lett 20: 92-6 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.029
BindingDB Entry DOI: 10.7270/Q2J1038R
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50305352
PNG
((S)-2-((R)-1-aminopropan-2-yloxy)-3-(1-phenyl-1H-i...)
Show SMILES C[C@H](CN)O[C@@H](Cc1cn(cn1)-c1ccccc1)C(O)=O
Show InChI InChI=1S/C15H19N3O3/c1-11(8-16)21-14(15(19)20)7-12-9-18(10-17-12)13-5-3-2-4-6-13/h2-6,9-11,14H,7-8,16H2,1H3,(H,19,20)/t11-,14+/m1/s1
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7.5n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins


Bioorg Med Chem Lett 20: 92-6 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.029
BindingDB Entry DOI: 10.7270/Q2J1038R
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50305348
PNG
((S)-2-(2-aminoethoxy)-3-(1-(2-cyclohexylethyl)-1H-...)
Show SMILES NCCO[C@@H](Cc1cn(CCC2CCCCC2)cn1)C(O)=O
Show InChI InChI=1S/C16H27N3O3/c17-7-9-22-15(16(20)21)10-14-11-19(12-18-14)8-6-13-4-2-1-3-5-13/h11-13,15H,1-10,17H2,(H,20,21)/t15-/m0/s1
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8.20n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins


Bioorg Med Chem Lett 20: 92-6 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.029
BindingDB Entry DOI: 10.7270/Q2J1038R
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50226610
PNG
((2S)-5-AMINO-2-[(1-PROPYL-1H-IMIDAZOL-4-YL)METHYL]...)
Show SMILES CCCn1cnc(C[C@H](CCCN)C(O)=O)c1
Show InChI InChI=1S/C12H21N3O2/c1-2-6-15-8-11(14-9-15)7-10(12(16)17)4-3-5-13/h8-10H,2-7,13H2,1H3,(H,16,17)/t10-/m0/s1
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10n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of human TAFIa


J Med Chem 50: 6095-103 (2007)


Article DOI: 10.1021/jm0702433
BindingDB Entry DOI: 10.7270/Q2T153CG
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50305349
PNG
((+/-)-2-(2-aminoethoxy)-3-(1-butyl-1H-imidazol-4-y...)
Show SMILES CCCCn1cnc(CC(OCCN)C(O)=O)c1
Show InChI InChI=1S/C12H21N3O3/c1-2-3-5-15-8-10(14-9-15)7-11(12(16)17)18-6-4-13/h8-9,11H,2-7,13H2,1H3,(H,16,17)
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15n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins


Bioorg Med Chem Lett 20: 92-6 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.029
BindingDB Entry DOI: 10.7270/Q2J1038R
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50226610
PNG
((2S)-5-AMINO-2-[(1-PROPYL-1H-IMIDAZOL-4-YL)METHYL]...)
Show SMILES CCCn1cnc(C[C@H](CCCN)C(O)=O)c1
Show InChI InChI=1S/C12H21N3O2/c1-2-6-15-8-11(14-9-15)7-10(12(16)17)4-3-5-13/h8-10H,2-7,13H2,1H3,(H,16,17)/t10-/m0/s1
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16n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins


Bioorg Med Chem Lett 20: 92-6 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.029
BindingDB Entry DOI: 10.7270/Q2J1038R
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50226605
PNG
((+/-)-5-amino-2-((1-propyl-1H-imidazol-4-yl)methyl...)
Show SMILES CCCn1cnc(CC(CCCN)C(O)=O)c1
Show InChI InChI=1S/C12H21N3O2/c1-2-6-15-8-11(14-9-15)7-10(12(16)17)4-3-5-13/h8-10H,2-7,13H2,1H3,(H,16,17)
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46n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of human TAFIa


J Med Chem 50: 6095-103 (2007)


Article DOI: 10.1021/jm0702433
BindingDB Entry DOI: 10.7270/Q2T153CG
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50305350
PNG
((+/-)-2-(2-aminoethoxy)-3-(1-o-tolyl-1H-imidazol-4...)
Show SMILES Cc1ccccc1-n1cnc(CC(OCCN)C(O)=O)c1
Show InChI InChI=1S/C15H19N3O3/c1-11-4-2-3-5-13(11)18-9-12(17-10-18)8-14(15(19)20)21-7-6-16/h2-5,9-10,14H,6-8,16H2,1H3,(H,19,20)
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65n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins


Bioorg Med Chem Lett 20: 92-6 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.029
BindingDB Entry DOI: 10.7270/Q2J1038R
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50226598
PNG
((S)-2-(2-aminoethylamino)-3-(1-butyl-1H-imidazol-4...)
Show SMILES CCCCn1cnc(C[C@H](NCCN)C(O)=O)c1
Show InChI InChI=1S/C12H22N4O2/c1-2-3-6-16-8-10(15-9-16)7-11(12(17)18)14-5-4-13/h8-9,11,14H,2-7,13H2,1H3,(H,17,18)/t11-/m0/s1
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70n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of human TAFIa


J Med Chem 50: 6095-103 (2007)


Article DOI: 10.1021/jm0702433
BindingDB Entry DOI: 10.7270/Q2T153CG
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50226606
PNG
((S)-2-(2-aminoethylamino)-3-(1-propyl-1H-imidazol-...)
Show SMILES CCCn1cnc(C[C@H](NCCN)C(O)=O)c1
Show InChI InChI=1S/C11H20N4O2/c1-2-5-15-7-9(14-8-15)6-10(11(16)17)13-4-3-12/h7-8,10,13H,2-6,12H2,1H3,(H,16,17)/t10-/m0/s1
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84n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of human TAFIa


J Med Chem 50: 6095-103 (2007)


Article DOI: 10.1021/jm0702433
BindingDB Entry DOI: 10.7270/Q2T153CG
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50226597
PNG
((S)-2-(2-aminoethylamino)-3-(1-isobutyl-1H-imidazo...)
Show SMILES CC(C)Cn1cnc(C[C@H](NCCN)C(O)=O)c1
Show InChI InChI=1S/C12H22N4O2/c1-9(2)6-16-7-10(15-8-16)5-11(12(17)18)14-4-3-13/h7-9,11,14H,3-6,13H2,1-2H3,(H,17,18)/t11-/m0/s1
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100n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of human TAFIa


J Med Chem 50: 6095-103 (2007)


Article DOI: 10.1021/jm0702433
BindingDB Entry DOI: 10.7270/Q2T153CG
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50226611
PNG
((S)-2-(2-aminoethylamino)-3-(1-(3-hydroxypropyl)-1...)
Show SMILES NCCN[C@@H](Cc1cn(CCCO)cn1)C(O)=O
Show InChI InChI=1S/C11H20N4O3/c12-2-3-13-10(11(17)18)6-9-7-15(8-14-9)4-1-5-16/h7-8,10,13,16H,1-6,12H2,(H,17,18)/t10-/m0/s1
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111n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of human TAFIa


J Med Chem 50: 6095-103 (2007)


Article DOI: 10.1021/jm0702433
BindingDB Entry DOI: 10.7270/Q2T153CG
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50226614
PNG
((S)-2-(2-aminoethylamino)-3-(1-(cyclobutylmethyl)-...)
Show SMILES NCCN[C@@H](Cc1cn(CC2CCC2)cn1)C(O)=O
Show InChI InChI=1S/C13H22N4O2/c14-4-5-15-12(13(18)19)6-11-8-17(9-16-11)7-10-2-1-3-10/h8-10,12,15H,1-7,14H2,(H,18,19)/t12-/m0/s1
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124n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of human TAFIa


J Med Chem 50: 6095-103 (2007)


Article DOI: 10.1021/jm0702433
BindingDB Entry DOI: 10.7270/Q2T153CG
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50226613
PNG
((S)-2-(2-aminoethylamino)-3-(1-phenethyl-1H-imidaz...)
Show SMILES NCCN[C@@H](Cc1cn(CCc2ccccc2)cn1)C(O)=O
Show InChI InChI=1S/C16H22N4O2/c17-7-8-18-15(16(21)22)10-14-11-20(12-19-14)9-6-13-4-2-1-3-5-13/h1-5,11-12,15,18H,6-10,17H2,(H,21,22)/t15-/m0/s1
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140n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of human TAFIa


J Med Chem 50: 6095-103 (2007)


Article DOI: 10.1021/jm0702433
BindingDB Entry DOI: 10.7270/Q2T153CG
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50226607
PNG
((+/-)-2-((1H-imidazol-4-yl)methyl)-5-aminopentanoi...)
Show SMILES NCCCC(Cc1cnc[nH]1)C(O)=O
Show InChI InChI=1S/C9H15N3O2/c10-3-1-2-7(9(13)14)4-8-5-11-6-12-8/h5-7H,1-4,10H2,(H,11,12)(H,13,14)
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140n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of human TAFIa


J Med Chem 50: 6095-103 (2007)


Article DOI: 10.1021/jm0702433
BindingDB Entry DOI: 10.7270/Q2T153CG
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50226606
PNG
((S)-2-(2-aminoethylamino)-3-(1-propyl-1H-imidazol-...)
Show SMILES CCCn1cnc(C[C@H](NCCN)C(O)=O)c1
Show InChI InChI=1S/C11H20N4O2/c1-2-5-15-7-9(14-8-15)6-10(11(16)17)13-4-3-12/h7-8,10,13H,2-6,12H2,1H3,(H,16,17)/t10-/m0/s1
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150n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of active form of human recombinant TAFI assessed as substrate turnover every 15 seconds for 30 mins


Bioorg Med Chem Lett 20: 92-6 (2010)


Article DOI: 10.1016/j.bmcl.2009.11.029
BindingDB Entry DOI: 10.7270/Q2J1038R
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50226602
PNG
((S)-2-(2-aminoethylamino)-3-(1-pentyl-1H-imidazol-...)
Show SMILES CCCCCn1cnc(C[C@H](NCCN)C(O)=O)c1
Show InChI InChI=1S/C13H24N4O2/c1-2-3-4-7-17-9-11(16-10-17)8-12(13(18)19)15-6-5-14/h9-10,12,15H,2-8,14H2,1H3,(H,18,19)/t12-/m0/s1
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160n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of human TAFIa


J Med Chem 50: 6095-103 (2007)


Article DOI: 10.1021/jm0702433
BindingDB Entry DOI: 10.7270/Q2T153CG
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50226601
PNG
((2S)-2-[(2-aminoethyl)amino]-3-(1-methyl-1H-imidaz...)
Show SMILES Cn1cnc(C[C@H](NCCN)C(O)=O)c1
Show InChI InChI=1S/C9H16N4O2/c1-13-5-7(12-6-13)4-8(9(14)15)11-3-2-10/h5-6,8,11H,2-4,10H2,1H3,(H,14,15)/t8-/m0/s1
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235n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of human TAFIa


J Med Chem 50: 6095-103 (2007)


Article DOI: 10.1021/jm0702433
BindingDB Entry DOI: 10.7270/Q2T153CG
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50226599
PNG
((S)-2-(2-aminoethylamino)-3-(1-ethyl-1H-imidazol-4...)
Show SMILES CCn1cnc(C[C@H](NCCN)C(O)=O)c1
Show InChI InChI=1S/C10H18N4O2/c1-2-14-6-8(13-7-14)5-9(10(15)16)12-4-3-11/h6-7,9,12H,2-5,11H2,1H3,(H,15,16)/t9-/m0/s1
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250n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of human TAFIa


J Med Chem 50: 6095-103 (2007)


Article DOI: 10.1021/jm0702433
BindingDB Entry DOI: 10.7270/Q2T153CG
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50226608
PNG
((S)-2-(2-aminoethylamino)-3-(1-benzyl-1H-imidazol-...)
Show SMILES NCCN[C@@H](Cc1cn(Cc2ccccc2)cn1)C(O)=O
Show InChI InChI=1S/C15H20N4O2/c16-6-7-17-14(15(20)21)8-13-10-19(11-18-13)9-12-4-2-1-3-5-12/h1-5,10-11,14,17H,6-9,16H2,(H,20,21)/t14-/m0/s1
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269n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of human TAFIa


J Med Chem 50: 6095-103 (2007)


Article DOI: 10.1021/jm0702433
BindingDB Entry DOI: 10.7270/Q2T153CG
More data for this
Ligand-Target Pair
Carboxypeptidase B2 isoform A


(Homo sapiens (Human))
BDBM50226603
PNG
((+/-)-5-amino-2-(mercaptomethyl)pentanoic acid | C...)
Show SMILES NCCCC(CS)C(O)=O
Show InChI InChI=1S/C6H13NO2S/c7-3-1-2-5(4-10)6(8)9/h5,10H,1-4,7H2,(H,8,9)
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300n/an/an/an/an/an/an/an/a



Pfizer Inc

Curated by ChEMBL


Assay Description
Inhibition of human TAFIa


J Med Chem 50: 6095-103 (2007)


Article DOI: 10.1021/jm0702433
BindingDB Entry DOI: 10.7270/Q2T153CG
More data for this
Ligand-Target Pair
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