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Found 2192 hits Enz. Inhib. hit(s) with Target = 'Casein kinase II alpha/beta'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Casein Kinase II


(Homo sapiens (human))
BDBM92673
PNG
(Isoquinolinesulfonamide, CKI-6)
Show SMILES NCCNS(=O)(=O)c1cccc2ccncc12
Show InChI InChI=1S/C11H13N3O2S/c12-5-7-14-17(15,16)11-3-1-2-9-4-6-13-8-10(9)11/h1-4,6,8,14H,5,7,12H2
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n/an/a>3.00E+5n/an/an/an/a7.430



Nagoya University School of Medicine



Assay Description
Casein kinase activities were determined under the conditions as described by Huang et al (1982).


J Biol Chem 264: 4924-7 (1989)


BindingDB Entry DOI: 10.7270/Q2K072VK
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM50011236
PNG
(CHEMBL344314 | Isoquinoline-5-sulfonic acid (2-ami...)
Show SMILES NCCNS(=O)(=O)c1cccc2cnccc12
Show InChI InChI=1S/C11H13N3O2S/c12-5-7-14-17(15,16)11-3-1-2-9-8-13-6-4-10(9)11/h1-4,6,8,14H,5,7,12H2
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n/an/a>3.00E+5n/an/an/an/a7.430



Nagoya University School of Medicine



Assay Description
Casein kinase activities were determined under the conditions as described by Huang et al (1982).


J Biol Chem 264: 4924-7 (1989)


BindingDB Entry DOI: 10.7270/Q2K072VK
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM92674
PNG
(Isoquinolinesulfonamide, CKI-7)
Show SMILES NCCNS(=O)(=O)c1ccc(Cl)c2ccncc12
Show InChI InChI=1S/C11H12ClN3O2S/c12-10-1-2-11(18(16,17)15-6-4-13)9-7-14-5-3-8(9)10/h1-3,5,7,15H,4,6,13H2
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n/an/a 9.00E+4n/an/an/an/a7.430



Nagoya University School of Medicine



Assay Description
Casein kinase activities were determined under the conditions as described by Huang et al (1982).


J Biol Chem 264: 4924-7 (1989)


BindingDB Entry DOI: 10.7270/Q2K072VK
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM11319
PNG
((5-oxo-5,6-dihydroindolo[1,2-a]quinazolin-7-yl)ace...)
Show SMILES OC(=O)Cc1c2ccccc2n2c1[nH]c(=O)c1ccccc21
Show InChI InChI=1S/C17H12N2O3/c20-15(21)9-12-10-5-1-3-7-13(10)19-14-8-4-2-6-11(14)17(22)18-16(12)19/h1-8H,9H2,(H,18,22)(H,20,21)
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170 -38.2 390n/an/an/an/a7.522



University of Padova



Assay Description
In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...


Biochem J 374: 639-46 (2003)


Article DOI: 10.1042/BJ20030674
BindingDB Entry DOI: 10.7270/Q2BV7DTQ
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM11323
PNG
(4,5,6,7-tetrabromo-1H-1,2,3-benzotriazole | 4,5,6,...)
Show SMILES Brc1c(Br)c(Br)c2[nH]nnc2c1Br
Show InChI InChI=1S/C6HBr4N3/c7-1-2(8)4(10)6-5(3(1)9)11-13-12-6/h(H,11,12,13)
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400 -36.2 500n/an/an/an/a7.522



University of Padova



Assay Description
In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...


Biochem J 374: 639-46 (2003)


Article DOI: 10.1042/BJ20030674
BindingDB Entry DOI: 10.7270/Q2BV7DTQ
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM7458
PNG
(5,7-dihydroxy-2-(4-hydroxyphenyl)-4H-chromen-4-one...)
Show SMILES Oc1ccc(cc1)-c1cc(=O)c2c(O)cc(O)cc2o1
Show InChI InChI=1S/C15H10O5/c16-9-3-1-8(2-4-9)13-7-12(19)15-11(18)5-10(17)6-14(15)20-13/h1-7,16-18H
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740 -34.6n/an/an/an/an/a7.522



University of Padova



Assay Description
In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...


Biochem J 374: 639-46 (2003)


Article DOI: 10.1042/BJ20030674
BindingDB Entry DOI: 10.7270/Q2BV7DTQ
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM7460
PNG
(2-(3,4-dihydroxyphenyl)-3,5,7-trihydroxy-4H-chrome...)
Show SMILES Oc1cc(O)c2c(c1)oc(-c1ccc(O)c(O)c1)c(O)c2=O
Show InChI InChI=1S/C15H10O7/c16-7-4-10(19)12-11(5-7)22-15(14(21)13(12)20)6-1-2-8(17)9(18)3-6/h1-5,16-19,21H
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1.18E+3 -33.5n/an/an/an/an/a7.522



University of Padova



Assay Description
In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...


Biochem J 374: 639-46 (2003)


Article DOI: 10.1042/BJ20030674
BindingDB Entry DOI: 10.7270/Q2BV7DTQ
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM11318
PNG
(1,3,8-trihydroxy-6-methyl-9,10-dihydroanthracene-9...)
Show SMILES Cc1cc(O)c2C(=O)c3c(O)cc(O)cc3C(=O)c2c1
Show InChI InChI=1S/C15H10O5/c1-6-2-8-12(10(17)3-6)15(20)13-9(14(8)19)4-7(16)5-11(13)18/h2-5,16-18H,1H3
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1.85E+3 -32.4 890n/an/an/an/a7.522



University of Padova



Assay Description
In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...


Biochem J 374: 639-46 (2003)


Article DOI: 10.1042/BJ20030674
BindingDB Entry DOI: 10.7270/Q2BV7DTQ
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM11324
PNG
((2R,3R,4S,5R)-2-(5,6-dichloro-1H-1,3-benzodiazol-1...)
Show SMILES OC[C@H]1O[C@H]([C@H](O)[C@@H]1O)n1cnc2cc(Cl)c(Cl)cc12
Show InChI InChI=1S/C12H12Cl2N2O4/c13-5-1-7-8(2-6(5)14)16(4-15-7)12-11(19)10(18)9(3-17)20-12/h1-2,4,9-12,17-19H,3H2/t9-,10-,11-,12-/m1/s1
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4.50E+3 -30.2n/an/an/an/an/a7.522



University of Padova



Assay Description
In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...


Biochem J 374: 639-46 (2003)


Article DOI: 10.1042/BJ20030674
BindingDB Entry DOI: 10.7270/Q2BV7DTQ
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248077
PNG
(2-hydroxy-4-{[4-(4-methyl-1,1-dioxido-3-oxoisothia...)
Show SMILES CC1CS(=O)(=O)N(C1=O)c1ccc(cc1)C(=O)Nc1ccc(C(O)=O)c(O)c1
Show InChI InChI=1S/C18H16N2O7S/c1-10-9-28(26,27)20(17(10)23)13-5-2-11(3-6-13)16(22)19-12-4-7-14(18(24)25)15(21)8-12/h2-8,10,21H,9H2,1H3,(H,19,22)(H,24,25)
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n/an/a 1.95E+4n/an/an/an/a7.530



NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248078
PNG
(3-{[4-(4,4-dimethyl-1,1-dioxido-3-oxoisothiazolidi...)
Show SMILES CC1(C)CS(=O)(=O)N(C1=O)c1ccc(cc1)C(=O)Nc1cccc(c1)C(O)=O
Show InChI InChI=1S/C19H18N2O6S/c1-19(2)11-28(26,27)21(18(19)25)15-8-6-12(7-9-15)16(22)20-14-5-3-4-13(10-14)17(23)24/h3-10H,11H2,1-2H3,(H,20,22)(H,23,24)
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n/an/a 8.00E+3n/an/an/an/a7.530



NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248079
PNG
(5-{[4-(4,4-dimethyl-1,1-dioxido-3-oxoisothiazolidi...)
Show SMILES CC1(C)CS(=O)(=O)N(C1=O)c1ccc(cc1)C(=O)Nc1ccc(O)c(c1)C(O)=O
Show InChI InChI=1S/C19H18N2O7S/c1-19(2)10-29(27,28)21(18(19)26)13-6-3-11(4-7-13)16(23)20-12-5-8-15(22)14(9-12)17(24)25/h3-9,22H,10H2,1-2H3,(H,20,23)(H,24,25)
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n/an/a>3.00E+4n/an/an/an/a7.530



NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248080
PNG
(4-{[4-(4,4-dimethyl-1,1-dioxido-3-oxoisothiazolidi...)
Show SMILES CC1(C)CS(=O)(=O)N(C1=O)c1ccc(cc1)C(=O)Nc1ccc(C(O)=O)c(O)c1
Show InChI InChI=1S/C19H18N2O7S/c1-19(2)10-29(27,28)21(18(19)26)13-6-3-11(4-7-13)16(23)20-12-5-8-14(17(24)25)15(22)9-12/h3-9,22H,10H2,1-2H3,(H,20,23)(H,24,25)
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n/an/a>3.00E+4n/an/an/an/a7.530



NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248081
PNG
(3-{[2-chloro-4-(1,1-dioxido-3-oxoisothiazolidin-2-...)
Show SMILES OC(=O)c1cccc(NC(=O)c2ccc(cc2Cl)N2C(=O)CCS2(=O)=O)c1
Show InChI InChI=1S/C17H13ClN2O6S/c18-14-9-12(20-15(21)6-7-27(20,25)26)4-5-13(14)16(22)19-11-3-1-2-10(8-11)17(23)24/h1-5,8-9H,6-7H2,(H,19,22)(H,23,24)
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n/an/a 1.50E+3n/an/an/an/a7.530



NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248082
PNG
(5-{[2-chloro-4-(1,1-dioxido-3-oxoisothiazolidin-2-...)
Show SMILES OC(=O)c1cc(NC(=O)c2ccc(cc2Cl)N2C(=O)CCS2(=O)=O)ccc1O
Show InChI InChI=1S/C17H13ClN2O7S/c18-13-8-10(20-15(22)5-6-28(20,26)27)2-3-11(13)16(23)19-9-1-4-14(21)12(7-9)17(24)25/h1-4,7-8,21H,5-6H2,(H,19,23)(H,24,25)
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n/an/a 9.00E+3n/an/an/an/a7.530



NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248083
PNG
(4-{[2-chloro-4-(1,1-dioxido-3-oxoisothiazolidin-2-...)
Show SMILES OC(=O)c1ccc(NC(=O)c2ccc(cc2Cl)N2C(=O)CCS2(=O)=O)cc1O
Show InChI InChI=1S/C17H13ClN2O7S/c18-13-8-10(20-15(22)5-6-28(20,26)27)2-4-11(13)16(23)19-9-1-3-12(17(24)25)14(21)7-9/h1-4,7-8,21H,5-6H2,(H,19,23)(H,24,25)
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n/an/a 3.00E+3n/an/an/an/a7.530



NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248084
PNG
(4-{[2-chloro-4-(1,1-dioxido-3-oxoisothiazolidin-2-...)
Show SMILES OC(=O)c1ccc(NC(=O)c2ccc(cc2Cl)N2C(=O)CCS2(=O)=O)cc1
Show InChI InChI=1S/C17H13ClN2O6S/c18-14-9-12(20-15(21)7-8-27(20,25)26)5-6-13(14)16(22)19-11-3-1-10(2-4-11)17(23)24/h1-6,9H,7-8H2,(H,19,22)(H,23,24)
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n/an/a>3.00E+4n/an/an/an/a7.530



NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248085
PNG
(3-{[2-chloro-4-(4-methyl-1,1-dioxido-3-oxoisothiaz...)
Show SMILES CC1CS(=O)(=O)N(C1=O)c1ccc(C(=O)Nc2cccc(c2)C(O)=O)c(Cl)c1
Show InChI InChI=1S/C18H15ClN2O6S/c1-10-9-28(26,27)21(17(10)23)13-5-6-14(15(19)8-13)16(22)20-12-4-2-3-11(7-12)18(24)25/h2-8,10H,9H2,1H3,(H,20,22)(H,24,25)
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n/an/a 3.60E+3n/an/an/an/a7.530



NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248086
PNG
(5-{[2-chloro-4-(4-methyl-1,1-dioxido-3-oxoisothiaz...)
Show SMILES CC1CS(=O)(=O)N(C1=O)c1ccc(C(=O)Nc2ccc(O)c(c2)C(O)=O)c(Cl)c1
Show InChI InChI=1S/C18H15ClN2O7S/c1-9-8-29(27,28)21(17(9)24)11-3-4-12(14(19)7-11)16(23)20-10-2-5-15(22)13(6-10)18(25)26/h2-7,9,22H,8H2,1H3,(H,20,23)(H,25,26)
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n/an/a 6.00E+3n/an/an/an/a7.530



NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248087
PNG
(3-{[2-chloro-4-(4-methyl-1,1-dioxido-3-oxoisothiaz...)
Show SMILES CC1CS(=O)(=O)N(C1=O)c1ccc(C(=O)Nc2cc(ccc2O)C(O)=O)c(Cl)c1
Show InChI InChI=1S/C18H15ClN2O7S/c1-9-8-29(27,28)21(17(9)24)11-3-4-12(13(19)7-11)16(23)20-14-6-10(18(25)26)2-5-15(14)22/h2-7,9,22H,8H2,1H3,(H,20,23)(H,25,26)
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n/an/a 3.70E+3n/an/an/an/a7.530



NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248088
PNG
(4-{[2-chloro-4-(4-methyl-1,1-dioxido-3-oxoisothiaz...)
Show SMILES CC1CS(=O)(=O)N(C1=O)c1ccc(C(=O)Nc2ccc(C(O)=O)c(O)c2)c(Cl)c1
Show InChI InChI=1S/C18H15ClN2O7S/c1-9-8-29(27,28)21(17(9)24)11-3-5-12(14(19)7-11)16(23)20-10-2-4-13(18(25)26)15(22)6-10/h2-7,9,22H,8H2,1H3,(H,20,23)(H,25,26)
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n/an/a 3.50E+3n/an/an/an/a7.530



NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248089
PNG
(Methyl 5-{[2-chloro-4-(4-methyl-1,1-dioxido-3-oxoi...)
Show SMILES COC(=O)c1cc(NC(=O)c2ccc(cc2Cl)N2C(=O)C(C)CS2(=O)=O)ccc1O
Show InChI InChI=1S/C19H17ClN2O7S/c1-10-9-30(27,28)22(18(10)25)12-4-5-13(15(20)8-12)17(24)21-11-3-6-16(23)14(7-11)19(26)29-2/h3-8,10,23H,9H2,1-2H3,(H,21,24)
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n/an/a>3.00E+4n/an/an/an/a7.530



NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248090
PNG
(N-[4-(4-methyl-1,1-dioxido-3-oxoisothiazolidin-2-y...)
Show SMILES CC1CS(=O)(=O)N(C1=O)c1ccc(cc1)C(=O)NCC(O)=O
Show InChI InChI=1S/C13H14N2O6S/c1-8-7-22(20,21)15(13(8)19)10-4-2-9(3-5-10)12(18)14-6-11(16)17/h2-5,8H,6-7H2,1H3,(H,14,18)(H,16,17)
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NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248091
PNG
(N-[4-(4-methyl-1,1-dioxido-3-oxoisothiazolidin-2-y...)
Show SMILES CC1CS(=O)(=O)N(C1=O)c1ccc(cc1)C(=O)NCCC(O)=O
Show InChI InChI=1S/C14H16N2O6S/c1-9-8-23(21,22)16(14(9)20)11-4-2-10(3-5-11)13(19)15-7-6-12(17)18/h2-5,9H,6-8H2,1H3,(H,15,19)(H,17,18)
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NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248076
PNG
(4-hydroxy-3-{[4-(4-methyl-1,1-dioxido-3-oxoisothia...)
Show SMILES CC1CS(=O)(=O)N(C1=O)c1ccc(cc1)C(=O)Nc1cc(ccc1O)C(O)=O
Show InChI InChI=1S/C18H16N2O7S/c1-10-9-28(26,27)20(17(10)23)13-5-2-11(3-6-13)16(22)19-14-8-12(18(24)25)4-7-15(14)21/h2-8,10,21H,9H2,1H3,(H,19,22)(H,24,25)
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n/an/a 1.60E+4n/an/an/an/a7.530



NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248075
PNG
(2-hydroxy-5-{[4-(4-methyl-1,1-dioxido-3-oxoisothia...)
Show SMILES CC1CS(=O)(=O)N(C1=O)c1ccc(cc1)C(=O)Nc1ccc(O)c(c1)C(O)=O
Show InChI InChI=1S/C18H16N2O7S/c1-10-9-28(26,27)20(17(10)23)13-5-2-11(3-6-13)16(22)19-12-4-7-15(21)14(8-12)18(24)25/h2-8,10,21H,9H2,1H3,(H,19,22)(H,24,25)
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NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248074
PNG
(3-{[4-(4-methyl-1,1-dioxido-3-oxoisothiazolidin-2-...)
Show SMILES CC1CS(=O)(=O)N(C1=O)c1ccc(cc1)C(=O)Nc1cccc(c1)C(O)=O
Show InChI InChI=1S/C18H16N2O6S/c1-11-10-27(25,26)20(17(11)22)15-7-5-12(6-8-15)16(21)19-14-4-2-3-13(9-14)18(23)24/h2-9,11H,10H2,1H3,(H,19,21)(H,23,24)
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n/an/a 3.10E+3n/an/an/an/a7.530



NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248073
PNG
(4-{[4-(1,1-dioxido-3-oxoisothiazolidin-2-yl)benzoy...)
Show SMILES OC(=O)c1ccc(NC(=O)c2ccc(cc2)N2C(=O)CCS2(=O)=O)cc1O
Show InChI InChI=1S/C17H14N2O7S/c20-14-9-11(3-6-13(14)17(23)24)18-16(22)10-1-4-12(5-2-10)19-15(21)7-8-27(19,25)26/h1-6,9,20H,7-8H2,(H,18,22)(H,23,24)
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n/an/a 1.40E+4n/an/an/an/a7.530



NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248072
PNG
(5-{[4-(1,1-dioxido-3-oxoisothiazolidin-2-yl)benzoy...)
Show SMILES OC(=O)c1cc(NC(=O)c2ccc(cc2)N2C(=O)CCS2(=O)=O)ccc1O
Show InChI InChI=1S/C17H14N2O7S/c20-14-6-3-11(9-13(14)17(23)24)18-16(22)10-1-4-12(5-2-10)19-15(21)7-8-27(19,25)26/h1-6,9,20H,7-8H2,(H,18,22)(H,23,24)
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n/an/a 8.00E+3n/an/an/an/a7.530



NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248071
PNG
(3-{[4-(1,1-dioxido-3-oxoisothiazolidin-2-yl)benzoy...)
Show SMILES OC(=O)c1cccc(NC(=O)c2ccc(cc2)N2C(=O)CCS2(=O)=O)c1
Show InChI InChI=1S/C17H14N2O6S/c20-15-8-9-26(24,25)19(15)14-6-4-11(5-7-14)16(21)18-13-3-1-2-12(10-13)17(22)23/h1-7,10H,8-9H2,(H,18,21)(H,22,23)
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n/an/a 1.80E+3n/an/an/an/a7.530



NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM11322
PNG
((3-chloro-phenyl)-(4-{2-[2-(1H-imidazol-4-yl)-ethy...)
Show SMILES Clc1cccc(Nc2nccc(n2)-c2ccnc(NCCc3cnc[nH]3)c2)c1
Show InChI InChI=1S/C20H18ClN7/c21-15-2-1-3-16(11-15)27-20-25-9-6-18(28-20)14-4-7-23-19(10-14)24-8-5-17-12-22-13-26-17/h1-4,6-7,9-13H,5,8H2,(H,22,26)(H,23,24)(H,25,27,28)
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n/an/a 3.20E+3n/an/an/an/a7.522



University of Padova



Assay Description
In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...


Biochem J 374: 639-46 (2003)


Article DOI: 10.1042/BJ20030674
BindingDB Entry DOI: 10.7270/Q2BV7DTQ
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM11321
PNG
(4-{2-[(2-aminoethyl)amino]pyridin-4-yl}-N-(3-chlor...)
Show SMILES NCCNc1cc(ccn1)-c1ccnc(Nc2cccc(Cl)c2)n1
Show InChI InChI=1S/C17H17ClN6/c18-13-2-1-3-14(11-13)23-17-22-8-5-15(24-17)12-4-7-20-16(10-12)21-9-6-19/h1-5,7-8,10-11H,6,9,19H2,(H,20,21)(H,22,23,24)
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n/an/a 9.60E+3n/an/an/an/a7.522



University of Padova



Assay Description
In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...


Biochem J 374: 639-46 (2003)


Article DOI: 10.1042/BJ20030674
BindingDB Entry DOI: 10.7270/Q2BV7DTQ
More data for this
Ligand-Target Pair
Casein kinase II alpha/beta


(Homo sapiens (human)-Rattus norvegicus)
BDBM248092
PNG
(4-{[4-(4-methyl-1,1-dioxido-3-oxoisothiazolidin-2-...)
Show SMILES CC1CS(=O)(=O)N(C1=O)c1ccc(cc1)C(=O)NCCCC(O)=O
Show InChI InChI=1S/C15H18N2O6S/c1-10-9-24(22,23)17(15(10)21)12-6-4-11(5-7-12)14(20)16-8-2-3-13(18)19/h4-7,10H,2-3,8-9H2,1H3,(H,16,20)(H,18,19)
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NAS of Ukraine



Assay Description
Each test was performed twice in a total reaction volume of 30 μL, containing 6 μg of peptide substrate RRRDDDSDDD (New England Biolabs (UK) Lt...


J Enzyme Inhib Med Chem 29: 338-43 (2014)


Article DOI: 10.3109/14756366.2013.782024
BindingDB Entry DOI: 10.7270/Q2DB80RP
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM11320
PNG
(3-{[4-(2-{[3-(1,1,2,2-tetrafluoroethoxy)phenyl]ami...)
Show SMILES OCCCNc1cc(ccn1)-c1ccnc(Nc2cccc(OC(F)(F)C(F)F)c2)n1
Show InChI InChI=1S/C20H19F4N5O2/c21-18(22)20(23,24)31-15-4-1-3-14(12-15)28-19-27-9-6-16(29-19)13-5-8-26-17(11-13)25-7-2-10-30/h1,3-6,8-9,11-12,18,30H,2,7,10H2,(H,25,26)(H,27,28,29)
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n/an/a 3.60E+3n/an/an/an/a7.522



University of Padova



Assay Description
In vitro kinase assay using purified enzyme, was incubated at room temperature with substrate, and test compounds in the presence of 100 uM ATP/ [gam...


Biochem J 374: 639-46 (2003)


Article DOI: 10.1042/BJ20030674
BindingDB Entry DOI: 10.7270/Q2BV7DTQ
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM50214466
PNG
(CHEMBL398149 | N-(3-(8-cyano-4-(cyclopropylamino)p...)
Show SMILES CC(=O)Nc1cccc(Nc2nc(NC3CC3)n3ncc(C#N)c3n2)c1
Show InChI InChI=1S/C17H16N8O/c1-10(26)20-13-3-2-4-14(7-13)21-16-23-15-11(8-18)9-19-25(15)17(24-16)22-12-5-6-12/h2-4,7,9,12H,5-6H2,1H3,(H,20,26)(H2,21,22,23,24)
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0.260n/an/an/an/an/an/an/an/a



Polaris Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha


Bioorg Med Chem Lett 17: 4191-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.041
BindingDB Entry DOI: 10.7270/Q23778D9
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM50214473
PNG
(CHEMBL230354 | N-(3-(8-CYANO-4-(PHENYLAMINO)PYRAZO...)
Show SMILES CC(=O)Nc1cccc(Nc2nc(Nc3ccccc3)n3ncc(C#N)c3n2)c1
Show InChI InChI=1S/C20H16N8O/c1-13(29)23-16-8-5-9-17(10-16)24-19-26-18-14(11-21)12-22-28(18)20(27-19)25-15-6-3-2-4-7-15/h2-10,12H,1H3,(H,23,29)(H2,24,25,26,27)
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0.350n/an/an/an/an/an/an/an/a



Polaris Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha


Bioorg Med Chem Lett 17: 4191-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.041
BindingDB Entry DOI: 10.7270/Q23778D9
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM50214454
PNG
(CHEMBL230462 | N-(3-(8-cyano-4-(cyclobutylamino)py...)
Show SMILES CC(=O)Nc1cccc(Nc2nc(NC3CCC3)n3ncc(C#N)c3n2)c1
Show InChI InChI=1S/C18H18N8O/c1-11(27)21-14-6-3-7-15(8-14)22-17-24-16-12(9-19)10-20-26(16)18(25-17)23-13-4-2-5-13/h3,6-8,10,13H,2,4-5H2,1H3,(H,21,27)(H2,22,23,24,25)
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1.90n/an/an/an/an/an/an/an/a



Polaris Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha


Bioorg Med Chem Lett 17: 4191-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.041
BindingDB Entry DOI: 10.7270/Q23778D9
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM50214444
PNG
(2-(p-toluidino)-4-(phenylamino)pyrazolo[1,5-a][1,3...)
Show SMILES Cc1ccc(Nc2nc(Nc3ccccc3)n3ncc(C#N)c3n2)cc1
Show InChI InChI=1S/C19H15N7/c1-13-7-9-16(10-8-13)22-18-24-17-14(11-20)12-21-26(17)19(25-18)23-15-5-3-2-4-6-15/h2-10,12H,1H3,(H2,22,23,24,25)
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5n/an/an/an/an/an/an/an/a



Polaris Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha


Bioorg Med Chem Lett 17: 4191-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.041
BindingDB Entry DOI: 10.7270/Q23778D9
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM50214465
PNG
(2-(4-chlorobenzylamino)-4-(phenylamino)pyrazolo[1,...)
Show SMILES Clc1ccc(CNc2nc(Nc3ccccc3)n3ncc(C#N)c3n2)cc1
Show InChI InChI=1S/C19H14ClN7/c20-15-8-6-13(7-9-15)11-22-18-25-17-14(10-21)12-23-27(17)19(26-18)24-16-4-2-1-3-5-16/h1-9,12H,11H2,(H2,22,24,25,26)
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5n/an/an/an/an/an/an/an/a



Polaris Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha


Bioorg Med Chem Lett 17: 4191-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.041
BindingDB Entry DOI: 10.7270/Q23778D9
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM50214477
PNG
(4-(phenylamino)-2-(4-(pyridin-2-yl)piperazin-1-yl)...)
Show SMILES N#Cc1cnn2c(Nc3ccccc3)nc(nc12)N1CCN(CC1)c1ccccn1
Show InChI InChI=1S/C21H19N9/c22-14-16-15-24-30-19(16)26-20(27-21(30)25-17-6-2-1-3-7-17)29-12-10-28(11-13-29)18-8-4-5-9-23-18/h1-9,15H,10-13H2,(H,25,26,27)
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7n/an/an/an/an/an/an/an/a



Polaris Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha


Bioorg Med Chem Lett 17: 4191-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.041
BindingDB Entry DOI: 10.7270/Q23778D9
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM50214460
PNG
(2-(CYCLOHEXYLMETHYLAMINO)-4-(PHENYLAMINO)PYRAZOLO[...)
Show SMILES N#Cc1cnn2c(Nc3ccccc3)nc(NCC3CCCCC3)nc12
Show InChI InChI=1S/C19H21N7/c20-11-15-13-22-26-17(15)24-18(21-12-14-7-3-1-4-8-14)25-19(26)23-16-9-5-2-6-10-16/h2,5-6,9-10,13-14H,1,3-4,7-8,12H2,(H2,21,23,24,25)
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8n/an/an/an/an/an/an/an/a



Polaris Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha


Bioorg Med Chem Lett 17: 4191-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.041
BindingDB Entry DOI: 10.7270/Q23778D9
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM50214474
PNG
(CHEMBL230353 | N-(3-(8-cyano-4-(phenethylamino)pyr...)
Show SMILES CC(=O)Nc1cccc(Nc2nc(NCCc3ccccc3)n3ncc(C#N)c3n2)c1
Show InChI InChI=1S/C22H20N8O/c1-15(31)26-18-8-5-9-19(12-18)27-21-28-20-17(13-23)14-25-30(20)22(29-21)24-11-10-16-6-3-2-4-7-16/h2-9,12,14H,10-11H2,1H3,(H,26,31)(H2,24,27,28,29)
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8n/an/an/an/an/an/an/an/a



Polaris Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha


Bioorg Med Chem Lett 17: 4191-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.041
BindingDB Entry DOI: 10.7270/Q23778D9
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM50214448
PNG
(2-(3,4-dimethoxyphenylamino)-4-(phenylamino)pyrazo...)
Show SMILES COc1ccc(Nc2nc(Nc3ccccc3)n3ncc(C#N)c3n2)cc1OC
Show InChI InChI=1S/C20H17N7O2/c1-28-16-9-8-15(10-17(16)29-2)23-19-25-18-13(11-21)12-22-27(18)20(26-19)24-14-6-4-3-5-7-14/h3-10,12H,1-2H3,(H2,23,24,25,26)
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9n/an/an/an/an/an/an/an/a



Polaris Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha


Bioorg Med Chem Lett 17: 4191-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.041
BindingDB Entry DOI: 10.7270/Q23778D9
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM50214464
PNG
(CHEMBL230568 | N-(3-(8-methyl-4-(phenylamino)pyraz...)
Show SMILES CC(=O)Nc1cccc(Nc2nc(Nc3ccccc3)n3ncc(C)c3n2)c1
Show InChI InChI=1S/C20H19N7O/c1-13-12-21-27-18(13)25-19(26-20(27)24-15-7-4-3-5-8-15)23-17-10-6-9-16(11-17)22-14(2)28/h3-12H,1-2H3,(H,22,28)(H2,23,24,25,26)
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11n/an/an/an/an/an/an/an/a



Polaris Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha


Bioorg Med Chem Lett 17: 4191-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.041
BindingDB Entry DOI: 10.7270/Q23778D9
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM50214450
PNG
(2-(3,4-dihydroisoquinolin-2(1H)-yl)-4-(phenylamino...)
Show SMILES N#Cc1cnn2c(Nc3ccccc3)nc(nc12)N1CCc2ccccc2C1
Show InChI InChI=1S/C21H17N7/c22-12-17-13-23-28-19(17)25-20(26-21(28)24-18-8-2-1-3-9-18)27-11-10-15-6-4-5-7-16(15)14-27/h1-9,13H,10-11,14H2,(H,24,25,26)
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11n/an/an/an/an/an/an/an/a



Polaris Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha


Bioorg Med Chem Lett 17: 4191-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.041
BindingDB Entry DOI: 10.7270/Q23778D9
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM50214457
PNG
(2-(2,3-dihydro-1H-inden-2-ylamino)-4-(phenylamino)...)
Show SMILES N#Cc1cnn2c(Nc3ccccc3)nc(NC3Cc4ccccc4C3)nc12
Show InChI InChI=1S/C21H17N7/c22-12-16-13-23-28-19(16)26-20(27-21(28)25-17-8-2-1-3-9-17)24-18-10-14-6-4-5-7-15(14)11-18/h1-9,13,18H,10-11H2,(H2,24,25,26,27)
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12n/an/an/an/an/an/an/an/a



Polaris Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha


Bioorg Med Chem Lett 17: 4191-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.041
BindingDB Entry DOI: 10.7270/Q23778D9
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM50214453
PNG
(2-(isopentylamino)-4-(phenylamino)pyrazolo[1,5-a][...)
Show SMILES CC(C)CCNc1nc(Nc2ccccc2)n2ncc(C#N)c2n1
Show InChI InChI=1S/C17H19N7/c1-12(2)8-9-19-16-22-15-13(10-18)11-20-24(15)17(23-16)21-14-6-4-3-5-7-14/h3-7,11-12H,8-9H2,1-2H3,(H2,19,21,22,23)
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13n/an/an/an/an/an/an/an/a



Polaris Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha


Bioorg Med Chem Lett 17: 4191-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.041
BindingDB Entry DOI: 10.7270/Q23778D9
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM50359842
PNG
(CHEMBL1928905)
Show SMILES Cn1c(SCC(O)=O)nc2c(Br)c(Br)c(Br)c(Br)c12
Show InChI InChI=1S/C10H6Br4N2O2S/c1-16-9-7(14)5(12)4(11)6(13)8(9)15-10(16)19-2-3(17)18/h2H2,1H3,(H,17,18)
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13n/an/an/an/an/an/an/an/a



The John Paul II Catholic University of Lublin

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha catalytic subunit expressed in Escherichia coli BL21 (DE3) assessed as [33P]gamma-ATP incorporation into RRRADDSDDDDD s...


Eur J Med Chem 47: 345-50 (2012)


Article DOI: 10.1016/j.ejmech.2011.11.002
BindingDB Entry DOI: 10.7270/Q2377944
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM50214468
PNG
(4-(phenylamino)-2-(pyrrolidin-1-yl)pyrazolo[1,5-a]...)
Show SMILES N#Cc1cnn2c(Nc3ccccc3)nc(nc12)N1CCCC1
Show InChI InChI=1S/C16H15N7/c17-10-12-11-18-23-14(12)20-15(22-8-4-5-9-22)21-16(23)19-13-6-2-1-3-7-13/h1-3,6-7,11H,4-5,8-9H2,(H,19,20,21)
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14n/an/an/an/an/an/an/an/a



Polaris Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha


Bioorg Med Chem Lett 17: 4191-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.041
BindingDB Entry DOI: 10.7270/Q23778D9
More data for this
Ligand-Target Pair
Casein Kinase II


(Homo sapiens (human))
BDBM50214446
PNG
(2,4-bis(phenylamino)pyrazolo[1,5-a][1,3,5]triazine...)
Show SMILES N#Cc1cnn2c(Nc3ccccc3)nc(Nc3ccccc3)nc12
Show InChI InChI=1S/C18H13N7/c19-11-13-12-20-25-16(13)23-17(21-14-7-3-1-4-8-14)24-18(25)22-15-9-5-2-6-10-15/h1-10,12H,(H2,21,22,23,24)
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15n/an/an/an/an/an/an/an/a



Polaris Pharmaceuticals Inc.

Curated by ChEMBL


Assay Description
Inhibition of human CK2 alpha


Bioorg Med Chem Lett 17: 4191-5 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.041
BindingDB Entry DOI: 10.7270/Q23778D9
More data for this
Ligand-Target Pair
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