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Found 970 hits Enz. Inhib. hit(s) with Target = 'Casein kinase II subunit beta (CK2 beta)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220044
PNG
(US9303033, N47, Table 58A, Compound 11)
Show SMILES CC(C)(C)NC(=O)Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C18H22N8O3/c1-18(2,3)25-17(29)23-12-7-13(20-10-4-5-10)26-14(22-12)9(8-19-26)6-11-15(27)24-16(28)21-11/h6-8,10,20H,4-5H2,1-3H3,(H2,21,24,27,28)(H2,22,23,25,29)/b11-6-
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n/an/a 3.82E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220047
PNG
(US9303033, Q47, Table 58A, Compound 14)
Show SMILES O=C(Nc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)c1cccc(c1)C#N
Show InChI InChI=1S/C21H16N8O3/c22-9-11-2-1-3-12(6-11)19(30)27-16-8-17(24-14-4-5-14)29-18(26-16)13(10-23-29)7-15-20(31)28-21(32)25-15/h1-3,6-8,10,14,24H,4-5H2,(H,26,27,30)(H2,25,28,31,32)/b15-7-
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n/an/a 3.75E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220054
PNG
(US9303033, D49, Table 59A, Compound 14 | US9303033...)
Show SMILES Clc1ccccc1COc1nc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C19H16ClN7O3/c20-13-4-2-1-3-10(13)9-30-19-24-15-11(7-14-16(28)25-18(29)23-14)8-21-27(15)17(26-19)22-12-5-6-12/h1-4,7-8,12H,5-6,9H2,(H,22,24,26)(H2,23,25,28,29)/b14-7-
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n/an/a 1.97E+4n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220063
PNG
(BDBM220095 | US9303033, G48, Table 58A, Compound 3...)
Show SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(Nc3cccc(c3)-n3cccn3)nc12
Show InChI InChI=1S/C22H19N9O2/c32-21-17(27-22(33)29-21)9-13-12-24-31-19(26-14-5-6-14)11-18(28-20(13)31)25-15-3-1-4-16(10-15)30-8-2-7-23-30/h1-4,7-12,14,26H,5-6H2,(H,25,28)(H2,27,29,32,33)/b17-9-
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n/an/a 1.73E+4n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220066
PNG
(BDBM220085 | US9303033, J48, Table 58A, Compound 3...)
Show SMILES Cc1ccccc1-c1cc(F)ccc1CNc1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C27H24FN7O2/c1-15-4-2-3-5-20(15)21-11-18(28)7-6-16(21)13-29-23-12-24(31-19-8-9-19)35-25(33-23)17(14-30-35)10-22-26(36)34-27(37)32-22/h2-7,10-12,14,19,31H,8-9,13H2,1H3,(H,29,33)(H2,32,34,36,37)/b22-10-
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n/an/a 4.73E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220072
PNG
(US9303033, P48, Table 58A, Compound 39)
Show SMILES COc1cccc(NC(=O)Nc2cc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1
Show InChI InChI=1S/C21H20N8O4/c1-33-14-4-2-3-13(8-14)24-20(31)27-16-9-17(23-12-5-6-12)29-18(26-16)11(10-22-29)7-15-19(30)28-21(32)25-15/h2-4,7-10,12,23H,5-6H2,1H3,(H2,24,26,27,31)(H2,25,28,30,32)/b15-7-
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n/an/a 3.16E+4n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM220057
PNG
(US9303033, A48, Table 58A, Compound 24 | US9303033...)
Show SMILES Clc1ccc(COc2nc(NC3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)cc1
Show InChI InChI=1S/C19H16ClN7O3/c20-12-3-1-10(2-4-12)9-30-19-24-15-11(7-14-16(28)25-18(29)23-14)8-21-27(15)17(26-19)22-13-5-6-13/h1-4,7-8,13H,5-6,9H2,(H,22,24,26)(H2,23,25,28,29)/b14-7-
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n/an/a 3.28E+4n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 mM MOPS pH ...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218937
PNG
(US9303033, R4, Table 13A, Compound 26 | US9303033,...)
Show SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1ccncc1
Show InChI InChI=1S/C18H15N7O2/c26-17-14(23-18(27)24-17)7-11-9-20-25-15(21-12-1-2-12)8-13(22-16(11)25)10-3-5-19-6-4-10/h3-9,12,21H,1-2H2,(H2,23,24,26,27)/b14-7-
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n/an/a 48.7n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218938
PNG
(US9303033, S4, Table 13A, Compound 27 | US9303033,...)
Show SMILES NCc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C20H19N7O2/c21-9-11-2-1-3-12(6-11)15-8-17(23-14-4-5-14)27-18(24-15)13(10-22-27)7-16-19(28)26-20(29)25-16/h1-3,6-8,10,14,23H,4-5,9,21H2,(H2,25,26,28,29)/b16-7-
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n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218939
PNG
(US9303033, T4, Table 13A, Compound 28 | US9303033,...)
Show SMILES CC(O)c1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C21H20N6O3/c1-11(28)12-3-2-4-13(7-12)16-9-18(23-15-5-6-15)27-19(24-16)14(10-22-27)8-17-20(29)26-21(30)25-17/h2-4,7-11,15,23,28H,5-6H2,1H3,(H2,25,26,29,30)/b17-8-
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n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218940
PNG
(US9303033, U4, Table 13A, Compound 29 | US9303033,...)
Show SMILES CCCS(=O)(=O)Nc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C22H23N7O4S/c1-2-8-34(32,33)28-16-5-3-4-13(9-16)17-11-19(24-15-6-7-15)29-20(25-17)14(12-23-29)10-18-21(30)27-22(31)26-18/h3-5,9-12,15,24,28H,2,6-8H2,1H3,(H2,26,27,30,31)/b18-10-
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n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218941
PNG
(US9303033, L8, Table 22A, Compound 32 | US9303033,...)
Show SMILES O=C1NC(=O)\C(N1)=C\c1cnn2c(NC3CC3)cc(nc12)-c1cccnc1
Show InChI InChI=1S/C18H15N7O2/c26-17-14(23-18(27)24-17)6-11-9-20-25-15(21-12-3-4-12)7-13(22-16(11)25)10-2-1-5-19-8-10/h1-2,5-9,12,21H,3-4H2,(H2,23,24,26,27)/b14-6-
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n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218942
PNG
(US9303033, W4, Table 13A, Compound 31)
Show SMILES CNc1cc(nc2c(\C=C3/NC(=O)NC3=O)cnn12)-c1cccc(CNC(C)=O)c1
Show InChI InChI=1S/C20H19N7O3/c1-11(28)22-9-12-4-3-5-13(6-12)15-8-17(21-2)27-18(24-15)14(10-23-27)7-16-19(29)26-20(30)25-16/h3-8,10,21H,9H2,1-2H3,(H,22,28)(H2,25,26,29,30)/b16-7-
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n/an/a 2.08E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218943
PNG
(US9303033, N8, Table 22A, Compound 34 | US9303033,...)
Show SMILES CC(=O)c1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C21H18N6O3/c1-11(28)12-3-2-4-13(7-12)16-9-18(23-15-5-6-15)27-19(24-16)14(10-22-27)8-17-20(29)26-21(30)25-17/h2-4,7-10,15,23H,5-6H2,1H3,(H2,25,26,29,30)/b17-8-
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n/an/a 1.73E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218944
PNG
(US9303033, O8, Table 22A, Compound 35 | US9303033,...)
Show SMILES CCS(=O)(=O)Nc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C21H21N7O4S/c1-2-33(31,32)27-15-5-3-4-12(8-15)16-10-18(23-14-6-7-14)28-19(24-16)13(11-22-28)9-17-20(29)26-21(30)25-17/h3-5,8-11,14,23,27H,2,6-7H2,1H3,(H2,25,26,29,30)/b17-9-
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n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218945
PNG
(US9303033, P8, Table 22A, Compound 36 | US9303033,...)
Show SMILES CCCCS(=O)(=O)Nc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C23H25N7O4S/c1-2-3-9-35(33,34)29-17-6-4-5-14(10-17)18-12-20(25-16-7-8-16)30-21(26-18)15(13-24-30)11-19-22(31)28-23(32)27-19/h4-6,10-13,16,25,29H,2-3,7-9H2,1H3,(H2,27,28,31,32)/b19-11-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218947
PNG
(US9303033, B5, Table 13A, Compound 36 | US9303033,...)
Show SMILES COc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C20H18N6O3/c1-29-14-4-2-3-11(7-14)15-9-17(22-13-5-6-13)26-18(23-15)12(10-21-26)8-16-19(27)25-20(28)24-16/h2-4,7-10,13,22H,5-6H2,1H3,(H2,24,25,27,28)/b16-8-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218948
PNG
(US9303033, C5, Table 13A, Compound 37 | US9303033,...)
Show SMILES CN(c1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1)S(C)(=O)=O
Show InChI InChI=1S/C21H21N7O4S/c1-27(33(2,31)32)15-5-3-4-12(8-15)16-10-18(23-14-6-7-14)28-19(24-16)13(11-22-28)9-17-20(29)26-21(30)25-17/h3-5,8-11,14,23H,6-7H2,1-2H3,(H2,25,26,29,30)/b17-9-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218949
PNG
(US9303033, D5, Table 14A, Compound 1)
Show SMILES CC(C)N1CCN(CC1)C(=O)c1cc(ccc1F)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C27H29FN8O3/c1-15(2)34-7-9-35(10-8-34)26(38)19-11-16(3-6-20(19)28)21-13-23(30-18-4-5-18)36-24(31-21)17(14-29-36)12-22-25(37)33-27(39)32-22/h3,6,11-15,18,30H,4-5,7-10H2,1-2H3,(H2,32,33,37,39)/b22-12-
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n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218950
PNG
(US9303033, E5, Table 14A, Compound 2)
Show SMILES Fc1ccc(cc1C(=O)NCCN1CCCC1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C26H27FN8O3/c27-19-6-3-15(11-18(19)24(36)28-7-10-34-8-1-2-9-34)20-13-22(30-17-4-5-17)35-23(31-20)16(14-29-35)12-21-25(37)33-26(38)32-21/h3,6,11-14,17,30H,1-2,4-5,7-10H2,(H,28,36)(H2,32,33,37,38)/b21-12-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218951
PNG
(US9303033, F5, Table 14A, Compound 3)
Show SMILES Fc1ccc(cc1C(=O)N1CCOCC1)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C24H22FN7O4/c25-17-4-1-13(9-16(17)23(34)31-5-7-36-8-6-31)18-11-20(27-15-2-3-15)32-21(28-18)14(12-26-32)10-19-22(33)30-24(35)29-19/h1,4,9-12,15,27H,2-3,5-8H2,(H2,29,30,33,35)/b19-10-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218952
PNG
(US9303033, G5, Table 14A, Compound 4)
Show SMILES CN(C)CCNC(=O)c1cc(ccc1F)-c1cc(NC2CC2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C24H25FN8O3/c1-32(2)8-7-26-22(34)16-9-13(3-6-17(16)25)18-11-20(28-15-4-5-15)33-21(29-18)14(12-27-33)10-19-23(35)31-24(36)30-19/h3,6,9-12,15,28H,4-5,7-8H2,1-2H3,(H,26,34)(H2,30,31,35,36)/b19-10-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218953
PNG
(US9303033, H5, Table 15A, Compound 1)
Show SMILES COc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/SC(=O)NC3=O)c2n1
Show InChI InChI=1S/C20H17N5O3S/c1-28-14-4-2-3-11(7-14)15-9-17(22-13-5-6-13)25-18(23-15)12(10-21-25)8-16-19(26)24-20(27)29-16/h2-4,7-10,13,22H,5-6H2,1H3,(H,24,26,27)/b16-8-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218954
PNG
(US9303033, I5, Table 15A, Compound 2)
Show SMILES Fc1cc(ccn1)-c1cc(NC2CC2)n2ncc(\C=C3/SC(=O)NC3=O)c2n1
Show InChI InChI=1S/C18H13FN6O2S/c19-14-6-9(3-4-20-14)12-7-15(22-11-1-2-11)25-16(23-12)10(8-21-25)5-13-17(26)24-18(27)28-13/h3-8,11,22H,1-2H2,(H,24,26,27)/b13-5-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218955
PNG
(US9303033, J5, Table 15A, Compound 3)
Show SMILES NCc1cccc(c1)-c1cc(NC2CC2)n2ncc(\C=C3/SC(=O)NC3=O)c2n1
Show InChI InChI=1S/C20H18N6O2S/c21-9-11-2-1-3-12(6-11)15-8-17(23-14-4-5-14)26-18(24-15)13(10-22-26)7-16-19(27)25-20(28)29-16/h1-3,6-8,10,14,23H,4-5,9,21H2,(H,25,27,28)/b16-7-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218956
PNG
(US9303033, Example 47, Table 16, Compound 1)
Show SMILES Fc1cc(ccn1)-c1cc(NC2CC2)n2ncc(\C=C3/SC(=S)NC3=O)c2n1
Show InChI InChI=1S/C18H13FN6OS2/c19-14-6-9(3-4-20-14)12-7-15(22-11-1-2-11)25-16(23-12)10(8-21-25)5-13-17(26)24-18(27)28-13/h3-8,11,22H,1-2H2,(H,24,26,27)/b13-5-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218957
PNG
(US9303033, K5, Table 17A, Compound 1)
Show SMILES Clc1cccc(Nc2cc(NC3CCNCC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1
Show InChI InChI=1S/C21H21ClN8O2/c22-13-2-1-3-15(9-13)25-17-10-18(26-14-4-6-23-7-5-14)30-19(28-17)12(11-24-30)8-16-20(31)29-21(32)27-16/h1-3,8-11,14,23,26H,4-7H2,(H,25,28)(H2,27,29,31,32)/b16-8-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218958
PNG
(US9303033, L5, Table 17A, Compound 2)
Show SMILES Clc1cccc(Nc2cc(NC3CCN(CC3)C(=O)C3CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1
Show InChI InChI=1S/C25H25ClN8O3/c26-16-2-1-3-18(11-16)28-20-12-21(29-17-6-8-33(9-7-17)24(36)14-4-5-14)34-22(31-20)15(13-27-34)10-19-23(35)32-25(37)30-19/h1-3,10-14,17,29H,4-9H2,(H,28,31)(H2,30,32,35,37)/b19-10-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218959
PNG
(US9303033, M5, Table 17A, Compound 3)
Show SMILES CC(C)(C)C(=O)N1CCC(CC1)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12
Show InChI InChI=1S/C26H29ClN8O3/c1-26(2,3)24(37)34-9-7-17(8-10-34)30-21-13-20(29-18-6-4-5-16(27)12-18)32-22-15(14-28-35(21)22)11-19-23(36)33-25(38)31-19/h4-6,11-14,17,30H,7-10H2,1-3H3,(H,29,32)(H2,31,33,36,38)/b19-11-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218960
PNG
(US9303033, N5, Table 17A, Compound 4)
Show SMILES CN(C)C(=O)N1CCC(CC1)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12
Show InChI InChI=1S/C24H26ClN9O3/c1-32(2)24(37)33-8-6-16(7-9-33)28-20-12-19(27-17-5-3-4-15(25)11-17)30-21-14(13-26-34(20)21)10-18-22(35)31-23(36)29-18/h3-5,10-13,16,28H,6-9H2,1-2H3,(H,27,30)(H2,29,31,35,36)/b18-10-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218961
PNG
(US9303033, O5, Table 17A, Compound 5)
Show SMILES COC(=O)CN1CCC(CC1)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12
Show InChI InChI=1S/C24H25ClN8O4/c1-37-21(34)13-32-7-5-16(6-8-32)28-20-11-19(27-17-4-2-3-15(25)10-17)30-22-14(12-26-33(20)22)9-18-23(35)31-24(36)29-18/h2-4,9-12,16,28H,5-8,13H2,1H3,(H,27,30)(H2,29,31,35,36)/b18-9-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218962
PNG
(US9303033, P5, Table 17A, Compound 6)
Show SMILES OCCN1CCC(CC1)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12
Show InChI InChI=1S/C23H25ClN8O3/c24-15-2-1-3-17(11-15)26-19-12-20(27-16-4-6-31(7-5-16)8-9-33)32-21(29-19)14(13-25-32)10-18-22(34)30-23(35)28-18/h1-3,10-13,16,27,33H,4-9H2,(H,26,29)(H2,28,30,34,35)/b18-10-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218963
PNG
(US9303033, Q5, Table 17A, Compound 7)
Show SMILES CC(C)N1CCC(CC1)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12
Show InChI InChI=1S/C24H27ClN8O2/c1-14(2)32-8-6-17(7-9-32)28-21-12-20(27-18-5-3-4-16(25)11-18)30-22-15(13-26-33(21)22)10-19-23(34)31-24(35)29-19/h3-5,10-14,17,28H,6-9H2,1-2H3,(H,27,30)(H2,29,31,34,35)/b19-10-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218964
PNG
(US9303033, R5, Table 17A, Compound 8)
Show SMILES CC(C)CN1CCC(CC1)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12
Show InChI InChI=1S/C25H29ClN8O2/c1-15(2)14-33-8-6-18(7-9-33)29-22-12-21(28-19-5-3-4-17(26)11-19)31-23-16(13-27-34(22)23)10-20-24(35)32-25(36)30-20/h3-5,10-13,15,18,29H,6-9,14H2,1-2H3,(H,28,31)(H2,30,32,35,36)/b20-10-
PDB

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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218965
PNG
(US9303033, S5, Table 17A, Compound 9)
Show SMILES CC(C)(C)CC(=O)N1CCC(CC1)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12
Show InChI InChI=1S/C27H31ClN8O3/c1-27(2,3)14-23(37)35-9-7-18(8-10-35)31-22-13-21(30-19-6-4-5-17(28)12-19)33-24-16(15-29-36(22)24)11-20-25(38)34-26(39)32-20/h4-6,11-13,15,18,31H,7-10,14H2,1-3H3,(H,30,33)(H2,32,34,38,39)/b20-11-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218966
PNG
(US9303033, T5, Table 17A, Compound 10)
Show SMILES COC(=O)N1CCC(CC1)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12
Show InChI InChI=1S/C23H23ClN8O4/c1-36-23(35)31-7-5-15(6-8-31)27-19-11-18(26-16-4-2-3-14(24)10-16)29-20-13(12-25-32(19)20)9-17-21(33)30-22(34)28-17/h2-4,9-12,15,27H,5-8H2,1H3,(H,26,29)(H2,28,30,33,34)/b17-9-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218967
PNG
(US9303033, U5, Table 17A, Compound 11)
Show SMILES CC(O)CN1CCC(CC1)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12
Show InChI InChI=1S/C24H27ClN8O3/c1-14(34)13-32-7-5-17(6-8-32)28-21-11-20(27-18-4-2-3-16(25)10-18)30-22-15(12-26-33(21)22)9-19-23(35)31-24(36)29-19/h2-4,9-12,14,17,28,34H,5-8,13H2,1H3,(H,27,30)(H2,29,31,35,36)/b19-9-
PDB

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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218968
PNG
(US9303033, V5, Table 17A, Compound 12)
Show SMILES Clc1cccc(Nc2cc(NC3CCN(Cc4ccccn4)CC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1
Show InChI InChI=1S/C27H26ClN9O2/c28-18-4-3-6-20(13-18)31-23-14-24(32-19-7-10-36(11-8-19)16-21-5-1-2-9-29-21)37-25(34-23)17(15-30-37)12-22-26(38)35-27(39)33-22/h1-6,9,12-15,19,32H,7-8,10-11,16H2,(H,31,34)(H2,33,35,38,39)/b22-12-
PDB

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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218969
PNG
(US9303033, W5, Table 17A, Compound 13)
Show SMILES CCN1CCC(CC1)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12
Show InChI InChI=1S/C23H25ClN8O2/c1-2-31-8-6-16(7-9-31)27-20-12-19(26-17-5-3-4-15(24)11-17)29-21-14(13-25-32(20)21)10-18-22(33)30-23(34)28-18/h3-5,10-13,16,27H,2,6-9H2,1H3,(H,26,29)(H2,28,30,33,34)/b18-10-
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n/an/a>2.50E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218970
PNG
(US9303033, X5, Table 18A, Compound 1)
Show SMILES Clc1cccc(Nc2cc(SCc3ccccc3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1
Show InChI InChI=1S/C23H17ClN6O2S/c24-16-7-4-8-17(10-16)26-19-11-20(33-13-14-5-2-1-3-6-14)30-21(28-19)15(12-25-30)9-18-22(31)29-23(32)27-18/h1-12H,13H2,(H,26,28)(H2,27,29,31,32)/b18-9-
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n/an/a 2.24E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218971
PNG
(US9303033, Y5, Table 18A, Compound 2)
Show SMILES Clc1cccc(c1)-c1cc(SCc2ccccc2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C23H16ClN5O2S/c24-17-8-4-7-15(9-17)18-11-20(32-13-14-5-2-1-3-6-14)29-21(26-18)16(12-25-29)10-19-22(30)28-23(31)27-19/h1-12H,13H2,(H2,27,28,30,31)/b19-10-
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n/an/a 291n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218972
PNG
(US9303033, Z5, Table 18A, Compound 3)
Show SMILES Clc1cccc(Nc2cc(S(=O)Cc3ccccc3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1
Show InChI InChI=1S/C23H17ClN6O3S/c24-16-7-4-8-17(10-16)26-19-11-20(34(33)13-14-5-2-1-3-6-14)30-21(28-19)15(12-25-30)9-18-22(31)29-23(32)27-18/h1-12H,13H2,(H,26,28)(H2,27,29,31,32)/b18-9-
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n/an/a 297n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218973
PNG
(US9303033, A6, Table 18A, Compound 4)
Show SMILES Clc1cccc(c1)-c1cc(S(=O)Cc2ccccc2)n2ncc(\C=C3/NC(=O)NC3=O)c2n1
Show InChI InChI=1S/C23H16ClN5O3S/c24-17-8-4-7-15(9-17)18-11-20(33(32)13-14-5-2-1-3-6-14)29-21(26-18)16(12-25-29)10-19-22(30)28-23(31)27-19/h1-12H,13H2,(H2,27,28,30,31)/b19-10-
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n/an/a 209n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218974
PNG
(US9303033, B6, Table 19A, Compound 1)
Show SMILES Clc1cccc(Nc2cc(NC3CCCC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1
Show InChI InChI=1S/C21H20ClN7O2/c22-13-4-3-7-15(9-13)24-17-10-18(25-14-5-1-2-6-14)29-19(27-17)12(11-23-29)8-16-20(30)28-21(31)26-16/h3-4,7-11,14,25H,1-2,5-6H2,(H,24,27)(H2,26,28,30,31)/b16-8-
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n/an/a 343n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218975
PNG
(US9303033, C6, Table 19A, Compound 2)
Show SMILES CCOCCNc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12
Show InChI InChI=1S/C20H20ClN7O3/c1-2-31-7-6-22-17-10-16(24-14-5-3-4-13(21)9-14)26-18-12(11-23-28(17)18)8-15-19(29)27-20(30)25-15/h3-5,8-11,22H,2,6-7H2,1H3,(H,24,26)(H2,25,27,29,30)/b15-8-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218976
PNG
(US9303033, D6, Table 19A, Compound 3)
Show SMILES OCCNc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12
Show InChI InChI=1S/C18H16ClN7O3/c19-11-2-1-3-12(7-11)22-14-8-15(20-4-5-27)26-16(24-14)10(9-21-26)6-13-17(28)25-18(29)23-13/h1-3,6-9,20,27H,4-5H2,(H,22,24)(H2,23,25,28,29)/b13-6-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218977
PNG
(US9303033, E6, Table 19A, Compound 4)
Show SMILES Clc1cccc(Nc2cc(NCc3ccncc3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1
Show InChI InChI=1S/C22H17ClN8O2/c23-15-2-1-3-16(9-15)27-18-10-19(25-11-13-4-6-24-7-5-13)31-20(29-18)14(12-26-31)8-17-21(32)30-22(33)28-17/h1-10,12,25H,11H2,(H,27,29)(H2,28,30,32,33)/b17-8-
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n/an/a 1.33E+3n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218978
PNG
(US9303033, F6, Table 19A, Compound 5)
Show SMILES CC(C)Nc1cc(Nc2cccc(Cl)c2)nc2c(\C=C3/NC(=O)NC3=O)cnn12
Show InChI InChI=1S/C19H18ClN7O2/c1-10(2)22-16-8-15(23-13-5-3-4-12(20)7-13)25-17-11(9-21-27(16)17)6-14-18(28)26-19(29)24-14/h3-10,22H,1-2H3,(H,23,25)(H2,24,26,28,29)/b14-6-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218979
PNG
(US9303033, G6, Table 19A, Compound 6)
Show SMILES Clc1cccc(Nc2cc(NC3CCC3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1
Show InChI InChI=1S/C20H18ClN7O2/c21-12-3-1-6-14(8-12)23-16-9-17(24-13-4-2-5-13)28-18(26-16)11(10-22-28)7-15-19(29)27-20(30)25-15/h1,3,6-10,13,24H,2,4-5H2,(H,23,26)(H2,25,27,29,30)/b15-7-
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SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
Casein kinase II subunit beta (CK2 beta)


(Homo sapiens (Human))
BDBM218980
PNG
(US9303033, H6, Table 19A, Compound 7)
Show SMILES Clc1cccc(Nc2cc(NCc3ccccn3)n3ncc(\C=C4/NC(=O)NC4=O)c3n2)c1
Show InChI InChI=1S/C22H17ClN8O2/c23-14-4-3-6-15(9-14)27-18-10-19(25-12-16-5-1-2-7-24-16)31-20(29-18)13(11-26-31)8-17-21(32)30-22(33)28-17/h1-11,25H,12H2,(H,27,29)(H2,28,30,32,33)/b17-8-
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n/an/a 421n/an/an/an/a7.0n/a



SENHWA BIOSCIENCES, INC.

US Patent


Assay Description
5 uM ATP: Test compounds dissolved and diluted in DMSO (2 μl) were added to a reaction mixture comprising 10 μl of 5 Reaction Buffer (40 m...


US Patent US9303033 (2016)


BindingDB Entry DOI: 10.7270/Q2CN72RX
More data for this
Ligand-Target Pair
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