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Found 234 Enz. Inhib. hit(s) with Target = 'Cathepsin L2'
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM93450(Flavonid, 6[4,6])
Affinity DataIC50:  1.92E+4nMpH: 5.5 T: 2°CAssay Description:Recombinant human cathepsin V was expressed and purified as described previously.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM49933(6-methoxy-2-(4-methoxyphenyl)-1-benzopyran-4-one |...)
Affinity DataIC50:  1.20E+4nMpH: 5.5 T: 2°CAssay Description:Recombinant human cathepsin V was expressed and purified as described previously.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM93449(Flavonid, 6[4,3])
Affinity DataIC50: >5.00E+4nMpH: 5.5 T: 2°CAssay Description:Recombinant human cathepsin V was expressed and purified as described previously.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM93447(Flavonid, 6[3,6])
Affinity DataIC50:  2.90E+3nMpH: 5.5 T: 2°CAssay Description:Recombinant human cathepsin V was expressed and purified as described previously.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM93446(Flavonid, 6[3,3])
Affinity DataIC50:  4.10E+3nMpH: 5.5 T: 2°CAssay Description:Recombinant human cathepsin V was expressed and purified as described previously.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM93445(Flavonid, 6[3,2])
Affinity DataIC50:  1.60E+3nMpH: 5.5 T: 2°CAssay Description:Recombinant human cathepsin V was expressed and purified as described previously.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM93444(Flavonid, 6[3,1])
Affinity DataIC50:  800nMpH: 5.5 T: 2°CAssay Description:Recombinant human cathepsin V was expressed and purified as described previously.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM93443(Flavonid, 6[2,6])
Affinity DataIC50: >5.00E+4nMpH: 5.5 T: 2°CAssay Description:Recombinant human cathepsin V was expressed and purified as described previously.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM93448(Flavonid, 6[4,2])
Affinity DataIC50: >5.00E+4nMpH: 5.5 T: 2°CAssay Description:Recombinant human cathepsin V was expressed and purified as described previously.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM93434(Flavonid, 5a)
Affinity DataIC50: >5.00E+4nMpH: 5.5 T: 2°CAssay Description:Recombinant human cathepsin V was expressed and purified as described previously.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM93435(Flavonid, 5b)
Affinity DataIC50: >5.00E+4nMpH: 5.5 T: 2°CAssay Description:Recombinant human cathepsin V was expressed and purified as described previously.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM93436(Flavonid, 5c)
Affinity DataIC50: >5.00E+4nMpH: 5.5 T: 2°CAssay Description:Recombinant human cathepsin V was expressed and purified as described previously.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM93437(Flavonid, 6b)
Affinity DataIC50: >5.00E+4nMpH: 5.5 T: 2°CAssay Description:Recombinant human cathepsin V was expressed and purified as described previously.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM93438(Flavonid, 6d)
Affinity DataIC50:  1.20E+3nMpH: 5.5 T: 2°CAssay Description:Recombinant human cathepsin V was expressed and purified as described previously.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM93439(Flavonid, 6e)
Affinity DataIC50: >5.00E+4nMpH: 5.5 T: 2°CAssay Description:Recombinant human cathepsin V was expressed and purified as described previously.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM93451(Flavonid, 6[1,4])
Affinity DataIC50:  2.70E+3nMpH: 5.5 T: 2°CAssay Description:Recombinant human cathepsin V was expressed and purified as described previously.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM93440(Flavonid, 6[1,6])
Affinity DataIC50:  1.11E+4nMpH: 5.5 T: 2°CAssay Description:Recombinant human cathepsin V was expressed and purified as described previously.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM93441(Flavonid, 6[2,2])
Affinity DataIC50:  1.90E+4nMpH: 5.5 T: 2°CAssay Description:Recombinant human cathepsin V was expressed and purified as described previously.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM93442(Flavonid, 6[2,3])
Affinity DataIC50: >5.00E+4nMpH: 5.5 T: 2°CAssay Description:Recombinant human cathepsin V was expressed and purified as described previously.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM31975(Dipeptidyl nitrile inhibitor, 8)
Affinity DataIC50:  794nMpH: 7.0 T: 2°CAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM31974(Dipeptidyl nitrile inhibitor, 7)
Affinity DataIC50:  1.00E+3nMpH: 7.0 T: 2°CAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM31973(Dipeptidyl nitrile inhibitor, 6)
Affinity DataIC50:  6.31E+3nMpH: 7.0 T: 2°CAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM31972(Dipeptidyl nitrile inhibitor, 5)
Affinity DataIC50:  398nMpH: 7.0 T: 2°CAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM31971(Dipeptidyl nitrile inhibitor, 4)
Affinity DataIC50:  6.31E+3nMpH: 7.0 T: 2°CAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM31970(Dipeptidyl nitrile inhibitor, 1)
Affinity DataIC50:  794nMpH: 7.0 T: 2°CAssay Description:IC50 values for inhibition of Cathepsins were determined from dose dependent inhibition of cleavage of fluorogenic, AMC-tagged, peptide substrates.More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM19778((2S)-2-(1-benzofuran-2-ylformamido)-4-methyl-N-[(4...)
Affinity DataKi:  0.0630nMAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM19769((2S)-2-(1-benzofuran-2-ylformamido)-4-methyl-N-[(4...)
Affinity DataKi:  1.80nMAssay Description:Potential inhibitors were evaluated using the progress curve method. Assays were carried out in the presence of variable concentrations of test compo...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM103351(US8552202, Compound 3)
Affinity DataKi:  100nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM103364(US8552202, Compound 13)
Affinity DataKi:  170nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM50336482(CHEMBL1668599 | citibrasine)
Affinity DataKi:  200nMAssay Description:Inhibition of human recombinant cathepsin V expressed in Pichia pastoris by Lineweaver-Burk double-reciprocal plotsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM103358(US8552202, Compound 9)
Affinity DataKi:  240nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM50385972(CHEMBL2042470)
Affinity DataKi:  400nMAssay Description:Competitive inhibition of human recombinant cathepsin V expressed in Pichia pastoris using Z-Phe-Arg-MCA as substrate by Lineweaver-Burk plot analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM50336477(1,3,5-trihydroxy-4-methoxy-10-methyl-2,8-bis(3-met...)
Affinity DataKi:  500nMAssay Description:Inhibition of human recombinant cathepsin V expressed in Pichia pastoris by Lineweaver-Burk double-reciprocal plotsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM103350(US8552202, Compound 2)
Affinity DataKi:  700nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM50385984(CHEMBL2042454)
Affinity DataKi:  800nMAssay Description:Uncompetitive inhibition of human recombinant cathepsin V expressed in Pichia pastoris using Z-Phe-Arg-MCA as substrate by Lineweaver-Burk plot analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM50385977(CHEMBL2042446)
Affinity DataKi:  800nMAssay Description:Noncompetitive inhibition of human recombinant cathepsin V expressed in Pichia pastoris using Z-Phe-Arg-MCA as substrate by Lineweaver-Burk plot anal...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM50336481(CHEMBL451705 | citrusinine I | citrusinine-I)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of human recombinant cathepsin V expressed in Pichia pastoris by Lineweaver-Burk double-reciprocal plotsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM50385962(CHEMBL2042461)
Affinity DataKi:  1.10E+3nMAssay Description:Uncompetitive inhibition of human recombinant cathepsin V expressed in Pichia pastoris using Z-Phe-Arg-MCA as substrate by Lineweaver-Burk plot analy...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM50336478(1,3,5-trihydroxy-4-methoxy-2-(3-methylbut-2-enyl)-...)
Affinity DataKi:  1.10E+3nMAssay Description:Inhibition of human recombinant cathepsin V expressed in Pichia pastoris by Lineweaver-Burk double-reciprocal plotsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM50336476(1,3,5-trihydroxy-2,8-bis(3-methylbut-2-enyl)-10-me...)
Affinity DataKi:  1.20E+3nMAssay Description:Inhibition of human recombinant cathepsin V expressed in Pichia pastoris by Lineweaver-Burk double-reciprocal plotsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM50385966(CHEMBL2042465)
Affinity DataKi:  1.30E+3nMAssay Description:Competitive inhibition of human recombinant cathepsin V expressed in Pichia pastoris using Z-Phe-Arg-MCA as substrate by Lineweaver-Burk plot analysi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM50336486(3,4-dihydro-3,5,8-trihydroxy-6-methoxy-2,2,7-trime...)
Affinity DataKi:  1.70E+3nMAssay Description:Inhibition of human recombinant cathepsin V expressed in Pichia pastoris by Lineweaver-Burk double-reciprocal plotsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM103363(US8552202, Example 3)
Affinity DataKi:  1.70E+3nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM103365(US8552202, Compound 14)
Affinity DataKi:  1.80E+3nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM103349(US8552202, Compound 1)
Affinity DataKi:  1.90E+3nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM103357(US8552202, Compound 8)
Affinity DataKi:  2.00E+3nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM103367(US8552202, Example 4)
Affinity DataKi:  3.20E+3nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM50336480(1,3,5-trihydroxy-4-methoxy-10-methylacridone | CHE...)
Affinity DataKi:  4.20E+3nMAssay Description:Inhibition of human recombinant cathepsin V expressed in Pichia pastoris by Lineweaver-Burk double-reciprocal plotsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM50336485(2,3-dihydro-4,9-dihydroxy-2-(2-hydroxy-propan-2-yl...)
Affinity DataKi:  4.40E+3nMAssay Description:Inhibition of human recombinant cathepsin V expressed in Pichia pastoris by Lineweaver-Burk double-reciprocal plotsMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetCathepsin L2(Homo sapiens (Human))
Universidade Federal De SaO Carlo

LigandPNGBDBM103356(US8552202, Compound 7)
Affinity DataKi:  5.00E+3nMAssay Description:In vitro inhibition assay using cathepsin.More data for this Ligand-Target Pair
In DepthDetails US Patent
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