BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 423 hits Enz. Inhib. hit(s) with Target = 'Dual Specificity Protein Phosphatase 1'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35451
PNG
(2-(trifluoromethyl)-4-quinolinecarboxylic acid | 2...)
Show SMILES OC(=O)c1cc(nc2ccccc12)C(F)(F)F
Show InChI InChI=1S/C11H6F3NO2/c12-11(13,14)9-5-7(10(16)17)6-3-1-2-4-8(6)15-9/h1-5H,(H,16,17)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35452
PNG
(2,8-bis(trifluoromethyl)-4-quinolinecarboxylic aci...)
Show SMILES OC(=O)c1cc(nc2c(cccc12)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C12H5F6NO2/c13-11(14,15)7-3-1-2-5-6(10(20)21)4-8(12(16,17)18)19-9(5)7/h1-4H,(H,20,21)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35453
PNG
(2-(2-furanyl)-4-quinolinecarboxylic acid | 2-(2-fu...)
Show SMILES OC(=O)c1cc(nc2ccccc12)-c1ccco1
Show InChI InChI=1S/C14H9NO3/c16-14(17)10-8-12(13-6-3-7-18-13)15-11-5-2-1-4-9(10)11/h1-8H,(H,16,17)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35454
PNG
(2-cyclopropyl-4-quinolinecarboxylic acid | 2-cyclo...)
Show SMILES OC(=O)c1cc(nc2ccccc12)C1CC1
Show InChI InChI=1S/C13H11NO2/c15-13(16)10-7-12(8-5-6-8)14-11-4-2-1-3-9(10)11/h1-4,7-8H,5-6H2,(H,15,16)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35379
PNG
(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)
Show SMILES CC(C)Cn1c(N)c(C(=O)COC(=O)c2cc(nc3ccccc23)-c2ccco2)c(=O)n(C)c1=O
Show InChI InChI=1S/C25H24N4O6/c1-14(2)12-29-22(26)21(23(31)28(3)25(29)33)19(30)13-35-24(32)16-11-18(20-9-6-10-34-20)27-17-8-5-4-7-15(16)17/h4-11,14H,12-13,26H2,1-3H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

n/an/a 5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35455
PNG
(1-(cyclopropylmethyl)urea | CC-PMLSC-DMA-P126 | ci...)
Show SMILES NC(=O)NCC1CC1
Show InChI InChI=1S/C5H10N2O/c6-5(8)7-3-4-1-2-4/h4H,1-3H2,(H3,6,7,8)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35456
PNG
(CC-PMLSC-DMA-P128 | N'-(2,6-diketo-3-methyl-pyrimi...)
Show SMILES CN(C)C=Nc1cc(=O)[nH]c(=O)n1C
Show InChI InChI=1S/C8H12N4O2/c1-11(2)5-9-6-4-7(13)10-8(14)12(6)3/h4-5H,1-3H3,(H,10,13,14)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35457
PNG
(CC-PMLSC-DMA-P129 | N'-(3-benzyl-1-methyl-2,6-diox...)
Show SMILES CN(C)\C=N\c1cc(=O)n(C)c(=O)n1Cc1ccccc1
Show InChI InChI=1S/C15H18N4O2/c1-17(2)11-16-13-9-14(20)18(3)15(21)19(13)10-12-7-5-4-6-8-12/h4-9,11H,10H2,1-3H3/b16-11+
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35458
PNG
(2-cyano-N-(cyclopropylmethylcarbamoyl)acetamide | ...)
Show SMILES O=C(CC#N)NC(=O)NCC1CC1
Show InChI InChI=1S/C8H11N3O2/c9-4-3-7(12)11-8(13)10-5-6-1-2-6/h6H,1-3,5H2,(H2,10,11,12,13)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35459
PNG
(CC-PMLSC-DMA-P131 | N'-(1-benzyl-2,6-diketo-3-meth...)
Show SMILES CN(C)\C=N\c1cc(=O)n(Cc2ccccc2)c(=O)n1C
Show InChI InChI=1S/C15H18N4O2/c1-17(2)11-16-13-9-14(20)19(15(21)18(13)3)10-12-7-5-4-6-8-12/h4-9,11H,10H2,1-3H3/b16-11+
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Patents


Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35460
PNG
(6-amino-1-(cyclopropylmethyl)pyrimidine-2,4-dione ...)
Show SMILES Nc1cc(=O)[nH]c(=O)n1CC1CC1
Show InChI InChI=1S/C8H11N3O2/c9-6-3-7(12)10-8(13)11(6)4-5-1-2-5/h3,5H,1-2,4,9H2,(H,10,12,13)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35461
PNG
(6-amino-1-benzyl-3-methyl-pyrimidine-2,4-quinone |...)
Show SMILES Cn1c(=O)cc(N)n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C12H13N3O2/c1-14-11(16)7-10(13)15(12(14)17)8-9-5-3-2-4-6-9/h2-7H,8,13H2,1H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35462
PNG
(6-amino-1-methyl-3-(phenylmethyl)pyrimidine-2,4-di...)
Show SMILES Cn1c(N)cc(=O)n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C12H13N3O2/c1-14-10(13)7-11(16)15(12(14)17)8-9-5-3-2-4-6-9/h2-7H,8,13H2,1H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35463
PNG
(2-(2-furanyl)-4-quinolinecarboxylic acid [2-(4-ami...)
Show SMILES Cn1c(N)c(C(=O)COC(=O)c2cc(nc3ccccc23)-c2ccco2)c(=O)n(C)c1=O
Show InChI InChI=1S/C22H18N4O6/c1-25-19(23)18(20(28)26(2)22(25)30)16(27)11-32-21(29)13-10-15(17-8-5-9-31-17)24-14-7-4-3-6-12(13)14/h3-10H,11,23H2,1-2H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

n/an/a 2.06E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35464
PNG
(CC-PMLSC- DMA-P139 | N'-[3-(cyclopropylmethyl)-2,6...)
Show SMILES CN(C)C=Nc1cc(=O)[nH]c(=O)n1CC1CC1
Show InChI InChI=1S/C11H16N4O2/c1-14(2)7-12-9-5-10(16)13-11(17)15(9)6-8-3-4-8/h5,7-8H,3-4,6H2,1-2H3,(H,13,16,17)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35465
PNG
(2-cyclopropyl-4-quinolinecarboxylic acid [2-(4-ami...)
Show SMILES Cn1c(N)c(C(=O)COC(=O)c2cc(nc3ccccc23)C2CC2)c(=O)n(C)c1=O
Show InChI InChI=1S/C21H20N4O5/c1-24-18(22)17(19(27)25(2)21(24)29)16(26)10-30-20(28)13-9-15(11-7-8-11)23-14-6-4-3-5-12(13)14/h3-6,9,11H,7-8,10,22H2,1-2H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35466
PNG
(2-cyclopropyl-4-quinolinecarboxylic acid [2-[4-ami...)
Show SMILES CC(C)Cn1c(N)c(C(=O)COC(=O)c2cc(nc3ccccc23)C2CC2)c(=O)n(C)c1=O
Show InChI InChI=1S/C24H26N4O5/c1-13(2)11-28-21(25)20(22(30)27(3)24(28)32)19(29)12-33-23(31)16-10-18(14-8-9-14)26-17-7-5-4-6-15(16)17/h4-7,10,13-14H,8-9,11-12,25H2,1-3H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35467
PNG
(CC-PMLSC-DMA-P142 | N'-[3-(cyclopropylmethyl)-1-me...)
Show SMILES CN(C)\C=N\c1cc(=O)n(C)c(=O)n1CC1CC1
Show InChI InChI=1S/C12H18N4O2/c1-14(2)8-13-10-6-11(17)15(3)12(18)16(10)7-9-4-5-9/h6,8-9H,4-5,7H2,1-3H3/b13-8+
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35468
PNG
(6-amino-1-benzyl-5-(2-chloroacetyl)-3-methyl-pyrim...)
Show SMILES Cn1c(=O)c(C(=O)CCl)c(N)n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C14H14ClN3O3/c1-17-13(20)11(10(19)7-15)12(16)18(14(17)21)8-9-5-3-2-4-6-9/h2-6H,7-8,16H2,1H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35469
PNG
(2-(trifluoromethyl)-4-quinolinecarboxylic acid [2-...)
Show SMILES Cn1c(N)c(C(=O)COC(=O)c2cc(nc3ccccc23)C(F)(F)F)c(=O)n(C)c1=O
Show InChI InChI=1S/C19H15F3N4O5/c1-25-15(23)14(16(28)26(2)18(25)30)12(27)8-31-17(29)10-7-13(19(20,21)22)24-11-6-4-3-5-9(10)11/h3-7H,8,23H2,1-2H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35470
PNG
(2,8-bis(trifluoromethyl)-4-quinolinecarboxylic aci...)
Show SMILES Cn1c(N)c(C(=O)COC(=O)c2cc(nc3c(cccc23)C(F)(F)F)C(F)(F)F)c(=O)n(C)c1=O
Show InChI InChI=1S/C20H14F6N4O5/c1-29-15(27)13(16(32)30(2)18(29)34)11(31)7-35-17(33)9-6-12(20(24,25)26)28-14-8(9)4-3-5-10(14)19(21,22)23/h3-6H,7,27H2,1-2H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35471
PNG
(2-phenyl-4-quinolinecarboxylic acid [2-[4-amino-1-...)
Show SMILES Cn1c(=O)c(C(=O)COC(=O)c2cc(nc3ccccc23)-c2ccccc2)c(N)n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C30H24N4O5/c1-33-28(36)26(27(31)34(30(33)38)17-19-10-4-2-5-11-19)25(35)18-39-29(37)22-16-24(20-12-6-3-7-13-20)32-23-15-9-8-14-21(22)23/h2-16H,17-18,31H2,1H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a 5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35472
PNG
(6-amino-3-benzyl-5-(2-chloroacetyl)-1-methyl-pyrim...)
Show SMILES Cn1c(N)c(C(=O)CCl)c(=O)n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C14H14ClN3O3/c1-17-12(16)11(10(19)7-15)13(20)18(14(17)21)8-9-5-3-2-4-6-9/h2-6H,7-8,16H2,1H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35473
PNG
(2,8-bis(trifluoromethyl)-4-quinolinecarboxylic aci...)
Show SMILES CC(C)Cn1c(N)c(C(=O)COC(=O)c2cc(nc3c(cccc23)C(F)(F)F)C(F)(F)F)c(=O)n(C)c1=O
Show InChI InChI=1S/C23H20F6N4O5/c1-10(2)8-33-18(30)16(19(35)32(3)21(33)37)14(34)9-38-20(36)12-7-15(23(27,28)29)31-17-11(12)5-4-6-13(17)22(24,25)26/h4-7,10H,8-9,30H2,1-3H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35474
PNG
(2-(trifluoromethyl)-4-quinolinecarboxylic acid [2-...)
Show SMILES Cn1c(=O)c(C(=O)COC(=O)c2cc(nc3ccccc23)C(F)(F)F)c(N)n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C25H19F3N4O5/c1-31-22(34)20(21(29)32(24(31)36)12-14-7-3-2-4-8-14)18(33)13-37-23(35)16-11-19(25(26,27)28)30-17-10-6-5-9-15(16)17/h2-11H,12-13,29H2,1H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35475
PNG
(2,8-bis(trifluoromethyl)-4-quinolinecarboxylic aci...)
Show SMILES Cn1c(=O)c(C(=O)COC(=O)c2cc(nc3c(cccc23)C(F)(F)F)C(F)(F)F)c(N)n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C26H18F6N4O5/c1-35-22(38)19(21(33)36(24(35)40)11-13-6-3-2-4-7-13)17(37)12-41-23(39)15-10-18(26(30,31)32)34-20-14(15)8-5-9-16(20)25(27,28)29/h2-10H,11-12,33H2,1H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM33114
PNG
(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[4-ami...)
Show SMILES Cn1c(=O)c(C(=O)COC(=O)c2cc(nc3ccccc23)-c2ccco2)c(N)n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C28H22N4O6/c1-31-26(34)24(25(29)32(28(31)36)15-17-8-3-2-4-9-17)22(33)16-38-27(35)19-14-21(23-12-7-13-37-23)30-20-11-6-5-10-18(19)20/h2-14H,15-16,29H2,1H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a 1.34E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35476
PNG
(2-cyclopropyl-4-quinolinecarboxylic acid [2-[4-ami...)
Show SMILES Cn1c(=O)c(C(=O)COC(=O)c2cc(nc3ccccc23)C2CC2)c(N)n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C27H24N4O5/c1-30-25(33)23(24(28)31(27(30)35)14-16-7-3-2-4-8-16)22(32)15-36-26(34)19-13-21(17-11-12-17)29-20-10-6-5-9-18(19)20/h2-10,13,17H,11-12,14-15,28H2,1H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35477
PNG
(2-(trifluoromethyl)-4-quinolinecarboxylic acid [2-...)
Show SMILES Cn1c(N)c(C(=O)COC(=O)c2cc(nc3ccccc23)C(F)(F)F)c(=O)n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C25H19F3N4O5/c1-31-21(29)20(22(34)32(24(31)36)12-14-7-3-2-4-8-14)18(33)13-37-23(35)16-11-19(25(26,27)28)30-17-10-6-5-9-15(16)17/h2-11H,12-13,29H2,1H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35478
PNG
(2,8-bis(trifluoromethyl)-4-quinolinecarboxylic aci...)
Show SMILES Cn1c(N)c(C(=O)COC(=O)c2cc(nc3c(cccc23)C(F)(F)F)C(F)(F)F)c(=O)n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C26H18F6N4O5/c1-35-21(33)19(22(38)36(24(35)40)11-13-6-3-2-4-7-13)17(37)12-41-23(39)15-10-18(26(30,31)32)34-20-14(15)8-5-9-16(20)25(27,28)29/h2-10H,11-12,33H2,1H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35479
PNG
(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[6-ami...)
Show SMILES Cn1c(N)c(C(=O)COC(=O)c2cc(nc3ccccc23)-c2ccco2)c(=O)n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C28H22N4O6/c1-31-25(29)24(26(34)32(28(31)36)15-17-8-3-2-4-9-17)22(33)16-38-27(35)19-14-21(23-12-7-13-37-23)30-20-11-6-5-10-18(19)20/h2-14H,15-16,29H2,1H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a 1.69E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35480
PNG
(2-cyclopropyl-4-quinolinecarboxylic acid [2-[6-ami...)
Show SMILES Cn1c(N)c(C(=O)COC(=O)c2cc(nc3ccccc23)C2CC2)c(=O)n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C27H24N4O5/c1-30-24(28)23(25(33)31(27(30)35)14-16-7-3-2-4-8-16)22(32)15-36-26(34)19-13-21(17-11-12-17)29-20-10-6-5-9-18(19)20/h2-10,13,17H,11-12,14-15,28H2,1H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a 2.89E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35481
PNG
(2-phenyl-4-quinolinecarboxylic acid [2-[6-amino-1-...)
Show SMILES Cn1c(N)c(C(=O)COC(=O)c2cc(nc3ccccc23)-c2ccccc2)c(=O)n(Cc2ccccc2)c1=O
Show InChI InChI=1S/C30H24N4O5/c1-33-27(31)26(28(36)34(30(33)38)17-19-10-4-2-5-11-19)25(35)18-39-29(37)22-16-24(20-12-6-3-7-13-20)32-23-15-9-8-14-21(22)23/h2-16H,17-18,31H2,1H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35482
PNG
(2-(trifluoromethyl)-4-quinolinecarboxylic acid [2-...)
Show SMILES CC(C)Cn1c(N)c(C(=O)COC(=O)c2cc(nc3ccccc23)C(F)(F)F)c(=O)n(C)c1=O
Show InChI InChI=1S/C22H21F3N4O5/c1-11(2)9-29-18(26)17(19(31)28(3)21(29)33)15(30)10-34-20(32)13-8-16(22(23,24)25)27-14-7-5-4-6-12(13)14/h4-8,11H,9-10,26H2,1-3H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35483
PNG
(6-amino-5-(2-chloro-1-oxoethyl)-1-(cyclopropylmeth...)
Show SMILES Cn1c(=O)c(C(=O)CCl)c(N)n(CC2CC2)c1=O
Show InChI InChI=1S/C11H14ClN3O3/c1-14-10(17)8(7(16)4-12)9(13)15(11(14)18)5-6-2-3-6/h6H,2-5,13H2,1H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35484
PNG
(2-(2-furanyl)-4-quinolinecarboxylic acid [2-[6-ami...)
Show SMILES Cn1c(=O)c(C(=O)COC(=O)c2cc(nc3ccccc23)-c2ccco2)c(N)n(CC2CC2)c1=O
Show InChI InChI=1S/C25H22N4O6/c1-28-23(31)21(22(26)29(25(28)33)12-14-8-9-14)19(30)13-35-24(32)16-11-18(20-7-4-10-34-20)27-17-6-3-2-5-15(16)17/h2-7,10-11,14H,8-9,12-13,26H2,1H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a 2.46E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35485
PNG
(2,8-bis(trifluoromethyl)-4-quinolinecarboxylic aci...)
Show SMILES Cn1c(=O)c(C(=O)COC(=O)c2cc(nc3c(cccc23)C(F)(F)F)C(F)(F)F)c(N)n(CC2CC2)c1=O
Show InChI InChI=1S/C23H18F6N4O5/c1-32-19(35)16(18(30)33(21(32)37)8-10-5-6-10)14(34)9-38-20(36)12-7-15(23(27,28)29)31-17-11(12)3-2-4-13(17)22(24,25)26/h2-4,7,10H,5-6,8-9,30H2,1H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.023



CC_PMLSC

Curated by PubChem BioAssay


Assay Description
The MKP-1 dose response assay SAR support Assay - has been developed to test the activity of a series Analog compounds synthesized by the PMLSC Chemi...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q29G5K5D
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35397
PNG
(MLS000095109 | N-cyclopentyl-1-methyl-6-(4-methylp...)
Show SMILES CC1CCN(CC1)S(=O)(=O)c1ccc2n(C)cc(C(=O)NC3CCCC3)c(=O)c2c1
Show InChI InChI=1S/C22H29N3O4S/c1-15-9-11-25(12-10-15)30(28,29)17-7-8-20-18(13-17)21(26)19(14-24(20)2)22(27)23-16-5-3-4-6-16/h7-8,13-16H,3-6,9-12H2,1-2H3,(H,23,27)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.022



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2F769WQ
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35398
PNG
(4-[[6-(4-fluorobenzyl)-5-keto-7H-pyrrolo[3,4-b]pyr...)
Show SMILES CCOC(=O)c1ccc(Nc2n(Cc3ccc(F)cc3)c(=O)c3ccc[nH]c23)cc1
Show InChI InChI=1S/C23H20FN3O3/c1-2-30-23(29)16-7-11-18(12-8-16)26-21-20-19(4-3-13-25-20)22(28)27(21)14-15-5-9-17(24)10-6-15/h3-13,25-26H,2,14H2,1H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>5.00E+4n/an/an/an/a7.022



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2F769WQ
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35399
PNG
(3-(4-{[4-(4-fluorophenyl)piperazin-1-yl]carbonyl}p...)
Show SMILES CC12CC(NC(=O)N1c1ccc(cc1)C(=O)N1CCN(CC1)c1ccc(F)cc1)c1ccccc1O2
Show InChI InChI=1S/C28H27FN4O3/c1-28-18-24(23-4-2-3-5-25(23)36-28)30-27(35)33(28)22-10-6-19(7-11-22)26(34)32-16-14-31(15-17-32)21-12-8-20(29)9-13-21/h2-13,24H,14-18H2,1H3,(H,30,35)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
n/an/a>5.00E+4n/an/an/an/a7.022



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2F769WQ
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35400
PNG
(3-amino-N-(5-propylsulfanyl-1,3,4-thiadiazol-2-yl)...)
Show SMILES CCCSc1nnc(NC(=O)c2sc3nc(ccc3c2N)-c2cccs2)s1
Show InChI InChI=1S/C17H15N5OS4/c1-2-7-25-17-22-21-16(27-17)20-14(23)13-12(18)9-5-6-10(19-15(9)26-13)11-4-3-8-24-11/h3-6,8H,2,7,18H2,1H3,(H,20,21,23)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

n/an/a 1.24E+4n/an/an/an/a7.022



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2F769WQ
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM34390
PNG
(MLS000043492 | N-(4-methoxyphenyl)-N-(4-methyl-2-s...)
Show SMILES COC(=O)N(c1ccc(OC)cc1)P1(=S)OCCC(C)O1
Show InChI InChI=1S/C13H18NO5PS/c1-10-8-9-18-20(21,19-10)14(13(15)17-3)11-4-6-12(16-2)7-5-11/h4-7,10H,8-9H2,1-3H3
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>5.00E+4n/an/an/an/a7.022



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2F769WQ
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35401
PNG
(3-hydroxy-2-phenyl-2,3-dihydro-1,5-benzothiazepin-...)
Show SMILES OC1C(Sc2ccccc2NC1=O)c1ccccc1
Show InChI InChI=1S/C15H13NO2S/c17-13-14(10-6-2-1-3-7-10)19-12-9-5-4-8-11(12)16-15(13)18/h1-9,13-14,17H,(H,16,18)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents

n/an/a 2.01E+4n/an/an/an/a7.022



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2F769WQ
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35402
PNG
(MLS000093276 | N-[2-(4-morpholinyl)-5-(trifluorome...)
Show SMILES FC(F)(F)c1ccc(N2CCOCC2)c(Nc2nc3ccccc3n3cnnc23)c1
Show InChI InChI=1S/C20H17F3N6O/c21-20(22,23)13-5-6-16(28-7-9-30-10-8-28)15(11-13)26-18-19-27-24-12-29(19)17-4-2-1-3-14(17)25-18/h1-6,11-12H,7-10H2,(H,25,26)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2.27E+4n/an/an/an/a7.022



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2F769WQ
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM32096
PNG
((6-phenyl-4,5-dihydropyrazolo[4,3-e][1,3]benzothia...)
Show SMILES Nc1nc-2c(CCc3c-2cnn3-c2ccccc2)s1
Show InChI InChI=1S/C14H12N4S/c15-14-17-13-10-8-16-18(9-4-2-1-3-5-9)11(10)6-7-12(13)19-14/h1-5,8H,6-7H2,(H2,15,17)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a>5.00E+4n/an/an/an/a7.022



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2F769WQ
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35403
PNG
(MLS000094302 | SMR000029892 | cid_3242856 | methyl...)
Show SMILES COC(=O)c1ccccc1NC(=O)CN1C(=O)C2CCCN2c2ncc(Cl)cc12
Show InChI InChI=1S/C20H19ClN4O4/c1-29-20(28)13-5-2-3-6-14(13)23-17(26)11-25-16-9-12(21)10-22-18(16)24-8-4-7-15(24)19(25)27/h2-3,5-6,9-10,15H,4,7-8,11H2,1H3,(H,23,26)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a 3.59E+4n/an/an/an/a7.022



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2F769WQ
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35404
PNG
(6-(4-methoxyphenyl)-3-methyl-N-(6-methyl-2-pyridin...)
Show SMILES COc1ccc(cc1)-c1cn2c(C)c(sc2n1)C(=O)Nc1cccc(C)n1
Show InChI InChI=1S/C20H18N4O2S/c1-12-5-4-6-17(21-12)23-19(25)18-13(2)24-11-16(22-20(24)27-18)14-7-9-15(26-3)10-8-14/h4-11H,1-3H3,(H,21,23,25)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

n/an/a>5.00E+4n/an/an/an/a7.022



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2F769WQ
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35405
PNG
(3-(2-keto-1,3-benzoxazol-3-yl)-N-(2-methylcyclohex...)
Show SMILES CC1CCCCC1NC(=O)CCn1c2ccccc2oc1=O
Show InChI InChI=1S/C17H22N2O3/c1-12-6-2-3-7-13(12)18-16(20)10-11-19-14-8-4-5-9-15(14)22-17(19)21/h4-5,8-9,12-13H,2-3,6-7,10-11H2,1H3,(H,18,20)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
n/an/a>5.00E+4n/an/an/an/a7.022



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2F769WQ
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35406
PNG
(3-(2-furanylmethyl)-6-(4-morpholinyl)-2-sulfanylid...)
Show SMILES O=c1n(Cc2ccco2)c(=S)[nH]c2ccc(cc12)N1CCOCC1
Show InChI InChI=1S/C17H17N3O3S/c21-16-14-10-12(19-5-8-22-9-6-19)3-4-15(14)18-17(24)20(16)11-13-2-1-7-23-13/h1-4,7,10H,5-6,8-9,11H2,(H,18,24)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem
n/an/a>5.00E+4n/an/an/an/a7.022



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2F769WQ
More data for this
Ligand-Target Pair
Dual Specificity Protein Phosphatase 1


(Homo sapiens)
BDBM35407
PNG
(8-(cyclohexoxycarbonyl)-3a,4,5,9b-tetrahydro-3H-cy...)
Show SMILES OC(=O)C1Nc2ccc(cc2C2C=CCC12)C(=O)OC1CCCCC1
Show InChI InChI=1S/C20H23NO4/c22-19(23)18-15-8-4-7-14(15)16-11-12(9-10-17(16)21-18)20(24)25-13-5-2-1-3-6-13/h4,7,9-11,13-15,18,21H,1-3,5-6,8H2,(H,22,23)
PDB
MMDB

NCI pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

n/an/a 7.66E+3n/an/an/an/a7.022



University of Pittsburgh Molecular Library Screening Center

Curated by PubChem BioAssay


Assay Description
The MKP-1 HTS confirmation dose response assay has been developed to confirm actives identified in the MH-76391 In vitro HTS assay for MKP-1 inhibito...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2F769WQ
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 423 total )  |  Next  |  Last  >>
Jump to: