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Found 1857 hits Enz. Inhib. hit(s) with Target = 'Fibroblast growth factor receptor 3'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194886
PNG
(US9206184, 67)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNC(C)=O)c(CN2CCNC(=O)C2)n2ncnc(N)c12
Show InChI InChI=1S/C24H27N7O3S/c1-13-6-15-8-19(35-23(15)18(7-13)34-3)21-16(9-27-14(2)32)17(10-30-5-4-26-20(33)11-30)31-22(21)24(25)28-12-29-31/h6-8,12H,4-5,9-11H2,1-3H3,(H,26,33)(H,27,32)(H2,25,28,29)
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n/an/a 9.40n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194887
PNG
(US9206184, 68)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CO)c(C#N)n2ncnc(N)c12
Show InChI InChI=1S/C18H15N5O2S/c1-9-3-10-5-14(26-17(10)13(4-9)25-2)15-11(7-24)12(6-19)23-16(15)18(20)21-8-22-23/h3-5,8,24H,7H2,1-2H3,(H2,20,21,22)
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n/an/a 42.7n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194888
PNG
(US9206184, 69)
Show SMILES COCc1c(C#N)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C19H17N5O2S/c1-10-4-11-6-15(27-18(11)14(5-10)26-3)16-12(8-25-2)13(7-20)24-17(16)19(21)22-9-23-24/h4-6,9H,8H2,1-3H3,(H2,21,22,23)
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n/an/a 58.1n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194890
PNG
(US9206184, 71)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCNC(=O)C2)c(C#N)n2ncnc(N)c12
Show InChI InChI=1S/C22H21N7O2S/c1-12-5-13-7-17(32-21(13)16(6-12)31-2)19-14(9-28-4-3-25-18(30)10-28)15(8-23)29-20(19)22(24)26-11-27-29/h5-7,11H,3-4,9-10H2,1-2H3,(H,25,30)(H2,24,26,27)
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n/an/a 5.40n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194891
PNG
(US9206184, 72)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNC(C)=O)c(CNC(C)=O)n2ncnc(N)c12
Show InChI InChI=1S/C22H24N6O3S/c1-11-5-14-7-18(32-21(14)17(6-11)31-4)19-15(8-24-12(2)29)16(9-25-13(3)30)28-20(19)22(23)26-10-27-28/h5-7,10H,8-9H2,1-4H3,(H,24,29)(H,25,30)(H2,23,26,27)
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n/an/a 0.700n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194892
PNG
(US9206184, 73)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CO)c(n2ncnc(N)c12)C(C)(C)O
Show InChI InChI=1S/C20H22N4O3S/c1-10-5-11-7-14(28-17(11)13(6-10)27-4)15-12(8-25)18(20(2,3)26)24-16(15)19(21)22-9-23-24/h5-7,9,25-26H,8H2,1-4H3,(H2,21,22,23)
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n/an/a 12.2n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194893
PNG
(US9206184, 74)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCNC(=O)C2)c(n2ncnc(N)c12)C(C)(C)O
Show InChI InChI=1S/C24H28N6O3S/c1-13-7-14-9-17(34-21(14)16(8-13)33-4)19-15(10-29-6-5-26-18(31)11-29)22(24(2,3)32)30-20(19)23(25)27-12-28-30/h7-9,12,32H,5-6,10-11H2,1-4H3,(H,26,31)(H2,25,27,28)
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n/an/a 1.40n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194894
PNG
(US9206184, 75)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CO)c(C)n2ncnc(N)c12
Show InChI InChI=1S/C18H18N4O2S/c1-9-4-11-6-14(25-17(11)13(5-9)24-3)15-12(7-23)10(2)22-16(15)18(19)20-8-21-22/h4-6,8,23H,7H2,1-3H3,(H2,19,20,21)
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n/an/a 19.8n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194895
PNG
(US9206184, 76)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN2CCNC(=O)C2)c(C)n2ncnc(N)c12
Show InChI InChI=1S/C22H24N6O2S/c1-12-6-14-8-17(31-21(14)16(7-12)30-3)19-15(9-27-5-4-24-18(29)10-27)13(2)28-20(19)22(23)25-11-26-28/h6-8,11H,4-5,9-10H2,1-3H3,(H,24,29)(H2,23,25,26)
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n/an/a 1.40n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194896
PNG
(US9206184, 77 | US9206184, 78)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNCC(C)(C)O)c(C)n2ncnc(N)c12
Show InChI InChI=1S/C22H27N5O2S/c1-12-6-14-8-17(30-20(14)16(7-12)29-5)18-15(9-24-10-22(3,4)28)13(2)27-19(18)21(23)25-11-26-27/h6-8,11,24,28H,9-10H2,1-5H3,(H2,23,25,26)
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n/an/a 3.80n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194896
PNG
(US9206184, 77 | US9206184, 78)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNCC(C)(C)O)c(C)n2ncnc(N)c12
Show InChI InChI=1S/C22H27N5O2S/c1-12-6-14-8-17(30-20(14)16(7-12)29-5)18-15(9-24-10-22(3,4)28)13(2)27-19(18)21(23)25-11-26-27/h6-8,11,24,28H,9-10H2,1-5H3,(H2,23,25,26)
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n/an/a 2n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194820
PNG
(US9206184, 1 | US9206184, 2)
Show SMILES COCc1c(CN2CCNC(=O)C2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C23H26N6O3S/c1-13-6-14-8-18(33-22(14)17(7-13)32-3)20-15(11-31-2)16(9-28-5-4-25-19(30)10-28)29-21(20)23(24)26-12-27-29/h6-8,12H,4-5,9-11H2,1-3H3,(H,25,30)(H2,24,26,27)
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n/an/a 24.8n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194820
PNG
(US9206184, 1 | US9206184, 2)
Show SMILES COCc1c(CN2CCNC(=O)C2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C23H26N6O3S/c1-13-6-14-8-18(33-22(14)17(7-13)32-3)20-15(11-31-2)16(9-28-5-4-25-19(30)10-28)29-21(20)23(24)26-12-27-29/h6-8,12H,4-5,9-11H2,1-3H3,(H,25,30)(H2,24,26,27)
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n/an/a 29.4n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194822
PNG
(US9206184, 3 | US9206184, 4)
Show SMILES COCc1c(CN[C@@H]2CCNC2=O)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C23H26N6O3S/c1-12-6-13-8-18(33-21(13)17(7-12)32-3)19-14(10-31-2)16(9-26-15-4-5-25-23(15)30)29-20(19)22(24)27-11-28-29/h6-8,11,15,26H,4-5,9-10H2,1-3H3,(H,25,30)(H2,24,27,28)/t15-/m1/s1
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n/an/a 46.6n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194822
PNG
(US9206184, 3 | US9206184, 4)
Show SMILES COCc1c(CN[C@@H]2CCNC2=O)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C23H26N6O3S/c1-12-6-13-8-18(33-21(13)17(7-12)32-3)19-14(10-31-2)16(9-26-15-4-5-25-23(15)30)29-20(19)22(24)27-11-28-29/h6-8,11,15,26H,4-5,9-10H2,1-3H3,(H,25,30)(H2,24,27,28)/t15-/m1/s1
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n/an/a 24.8n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194824
PNG
(US9206184, 5 | US9206184, 6)
Show SMILES CCOCc1c(CN2CCNC(=O)C2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C24H28N6O3S/c1-4-33-12-16-17(10-29-6-5-26-20(31)11-29)30-22(24(25)27-13-28-30)21(16)19-9-15-7-14(2)8-18(32-3)23(15)34-19/h7-9,13H,4-6,10-12H2,1-3H3,(H,26,31)(H2,25,27,28)
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n/an/a 12.1n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194824
PNG
(US9206184, 5 | US9206184, 6)
Show SMILES CCOCc1c(CN2CCNC(=O)C2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C24H28N6O3S/c1-4-33-12-16-17(10-29-6-5-26-20(31)11-29)30-22(24(25)27-13-28-30)21(16)19-9-15-7-14(2)8-18(32-3)23(15)34-19/h7-9,13H,4-6,10-12H2,1-3H3,(H,26,31)(H2,25,27,28)
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n/an/a 28.5n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194826
PNG
(US9206184, 7 | US9206184, 8)
Show SMILES CCOCc1c(CN[C@@H]2CCNC2=O)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C24H28N6O3S/c1-4-33-11-15-17(10-27-16-5-6-26-24(16)31)30-21(23(25)28-12-29-30)20(15)19-9-14-7-13(2)8-18(32-3)22(14)34-19/h7-9,12,16,27H,4-6,10-11H2,1-3H3,(H,26,31)(H2,25,28,29)/t16-/m1/s1
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n/an/a 10.4n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194826
PNG
(US9206184, 7 | US9206184, 8)
Show SMILES CCOCc1c(CN[C@@H]2CCNC2=O)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C24H28N6O3S/c1-4-33-11-15-17(10-27-16-5-6-26-24(16)31)30-21(23(25)28-12-29-30)20(15)19-9-14-7-13(2)8-18(32-3)22(14)34-19/h7-9,12,16,27H,4-6,10-11H2,1-3H3,(H,26,31)(H2,25,28,29)/t16-/m1/s1
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n/an/a 17.7n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194828
PNG
(US9206184, 9)
Show SMILES CCOCc1c(CNCC(N)=O)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C22H26N6O3S/c1-4-31-10-14-15(8-25-9-18(23)29)28-20(22(24)26-11-27-28)19(14)17-7-13-5-12(2)6-16(30-3)21(13)32-17/h5-7,11,25H,4,8-10H2,1-3H3,(H2,23,29)(H2,24,26,27)
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US Patent
n/an/a 63.9n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194829
PNG
(US9206184, 10)
Show SMILES CCOCc1c(CN2CCOCC2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C24H29N5O3S/c1-4-31-13-17-18(12-28-5-7-32-8-6-28)29-22(24(25)26-14-27-29)21(17)20-11-16-9-15(2)10-19(30-3)23(16)33-20/h9-11,14H,4-8,12-13H2,1-3H3,(H2,25,26,27)
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n/an/a 8.30n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194830
PNG
(US9206184, 11 | US9206184, 20)
Show SMILES CCOCc1c(CN2CCN(CC2)C(C)=O)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C26H32N6O3S/c1-5-35-14-19-20(13-30-6-8-31(9-7-30)17(3)33)32-24(26(27)28-15-29-32)23(19)22-12-18-10-16(2)11-21(34-4)25(18)36-22/h10-12,15H,5-9,13-14H2,1-4H3,(H2,27,28,29)
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n/an/a 13n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194831
PNG
(US9206184, 12)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CO)c(CN2CCNCC2)n2ncnc(N)c12
Show InChI InChI=1S/C22H26N6O2S/c1-13-7-14-9-18(31-21(14)17(8-13)30-2)19-15(11-29)16(10-27-5-3-24-4-6-27)28-20(19)22(23)25-12-26-28/h7-9,12,24,29H,3-6,10-11H2,1-2H3,(H2,23,25,26)
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n/an/a 14n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194832
PNG
(US9206184, 13)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CO)c(CN2CCNC(=O)C2)n2ncnc(N)c12
Show InChI InChI=1S/C22H24N6O3S/c1-12-5-13-7-17(32-21(13)16(6-12)31-2)19-14(10-29)15(8-27-4-3-24-18(30)9-27)28-20(19)22(23)25-11-26-28/h5-7,11,29H,3-4,8-10H2,1-2H3,(H,24,30)(H2,23,25,26)
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n/an/a 10n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194833
PNG
(US9206184, 14)
Show SMILES COCc1c(CN2CC[C@](C)(N)C2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C24H30N6O2S/c1-14-7-15-9-19(33-22(15)18(8-14)32-4)20-16(11-31-3)17(10-29-6-5-24(2,26)12-29)30-21(20)23(25)27-13-28-30/h7-9,13H,5-6,10-12,26H2,1-4H3,(H2,25,27,28)/t24-/m0/s1
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n/an/a 2.5n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194834
PNG
(US9206184, 15)
Show SMILES CCOCc1c(CN2CC[C@](C)(N)C2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C25H32N6O2S/c1-5-33-12-17-18(11-30-7-6-25(3,27)13-30)31-22(24(26)28-14-29-31)21(17)20-10-16-8-15(2)9-19(32-4)23(16)34-20/h8-10,14H,5-7,11-13,27H2,1-4H3,(H2,26,28,29)/t25-/m0/s1
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n/an/a 1n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194835
PNG
(US9206184, 16)
Show SMILES COCc1c(CN2CCN(CC2)C(C)=O)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C25H30N6O3S/c1-15-9-17-11-21(35-24(17)20(10-15)34-4)22-18(13-33-3)19(31-23(22)25(26)27-14-28-31)12-29-5-7-30(8-6-29)16(2)32/h9-11,14H,5-8,12-13H2,1-4H3,(H2,26,27,28)
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n/an/a 9.40n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194836
PNG
(US9206184, 17)
Show SMILES COCc1c(CN2CCNCC2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C23H28N6O2S/c1-14-8-15-10-19(32-22(15)18(9-14)31-3)20-16(12-30-2)17(11-28-6-4-25-5-7-28)29-21(20)23(24)26-13-27-29/h8-10,13,25H,4-7,11-12H2,1-3H3,(H2,24,26,27)
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n/an/a 3.30n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194837
PNG
(US9206184, 18 | US9206184, 19)
Show SMILES CCOCc1c(CN2CCNCC2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C24H30N6O2S/c1-4-32-13-17-18(12-29-7-5-26-6-8-29)30-22(24(25)27-14-28-30)21(17)20-11-16-9-15(2)10-19(31-3)23(16)33-20/h9-11,14,26H,4-8,12-13H2,1-3H3,(H2,25,27,28)
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n/an/a 2.80n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194837
PNG
(US9206184, 18 | US9206184, 19)
Show SMILES CCOCc1c(CN2CCNCC2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C24H30N6O2S/c1-4-32-13-17-18(12-29-7-5-26-6-8-29)30-22(24(25)27-14-28-30)21(17)20-11-16-9-15(2)10-19(31-3)23(16)33-20/h9-11,14,26H,4-8,12-13H2,1-3H3,(H2,25,27,28)
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n/an/a 2.70n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194830
PNG
(US9206184, 11 | US9206184, 20)
Show SMILES CCOCc1c(CN2CCN(CC2)C(C)=O)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C26H32N6O3S/c1-5-35-14-19-20(13-30-6-8-31(9-7-30)17(3)33)32-24(26(27)28-15-29-32)23(19)22-12-18-10-16(2)11-21(34-4)25(18)36-22/h10-12,15H,5-9,13-14H2,1-4H3,(H2,27,28,29)
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n/an/a 26.1n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194840
PNG
(US9206184, 21)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COCCO)c(CN2CCNC(=O)C2)n2ncnc(N)c12
Show InChI InChI=1S/C24H28N6O4S/c1-14-7-15-9-19(35-23(15)18(8-14)33-2)21-16(12-34-6-5-31)17(10-29-4-3-26-20(32)11-29)30-22(21)24(25)27-13-28-30/h7-9,13,31H,3-6,10-12H2,1-2H3,(H,26,32)(H2,25,27,28)
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n/an/a 13n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194841
PNG
(US9206184, 22)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COCCO)c(CN2CCNCC2)n2ncnc(N)c12
Show InChI InChI=1S/C24H30N6O3S/c1-15-9-16-11-20(34-23(16)19(10-15)32-2)21-17(13-33-8-7-31)18(12-29-5-3-26-4-6-29)30-22(21)24(25)27-14-28-30/h9-11,14,26,31H,3-8,12-13H2,1-2H3,(H2,25,27,28)
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n/an/a 4.70n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194842
PNG
(US9206184, 23)
Show SMILES CCCCOCc1c(CN2CCNCC2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C26H34N6O2S/c1-4-5-10-34-15-19-20(14-31-8-6-28-7-9-31)32-24(26(27)29-16-30-32)23(19)22-13-18-11-17(2)12-21(33-3)25(18)35-22/h11-13,16,28H,4-10,14-15H2,1-3H3,(H2,27,29,30)
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n/an/a 41.9n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194843
PNG
(US9206184, 24)
Show SMILES CCCOCc1c(CN2CCNCC2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C25H32N6O2S/c1-4-9-33-14-18-19(13-30-7-5-27-6-8-30)31-23(25(26)28-15-29-31)22(18)21-12-17-10-16(2)11-20(32-3)24(17)34-21/h10-12,15,27H,4-9,13-14H2,1-3H3,(H2,26,28,29)
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n/an/a 5.70n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194844
PNG
(US9206184, 25)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COCC2CC2)c(CN2CCNCC2)n2ncnc(N)c12
Show InChI InChI=1S/C26H32N6O2S/c1-16-9-18-11-22(35-25(18)21(10-16)33-2)23-19(14-34-13-17-3-4-17)20(12-31-7-5-28-6-8-31)32-24(23)26(27)29-15-30-32/h9-11,15,17,28H,3-8,12-14H2,1-2H3,(H2,27,29,30)
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n/an/a 5.20n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194845
PNG
(US9206184, 26)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COC2CCC2)c(CN2CCNCC2)n2ncnc(N)c12
Show InChI InChI=1S/C26H32N6O2S/c1-16-10-17-12-22(35-25(17)21(11-16)33-2)23-19(14-34-18-4-3-5-18)20(13-31-8-6-28-7-9-31)32-24(23)26(27)29-15-30-32/h10-12,15,18,28H,3-9,13-14H2,1-2H3,(H2,27,29,30)
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n/an/a 4.90n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194846
PNG
(US9206184, 27)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COC(C)C)c(CN2CCNCC2)n2ncnc(N)c12
Show InChI InChI=1S/C25H32N6O2S/c1-15(2)33-13-18-19(12-30-7-5-27-6-8-30)31-23(25(26)28-14-29-31)22(18)21-11-17-9-16(3)10-20(32-4)24(17)34-21/h9-11,14-15,27H,5-8,12-13H2,1-4H3,(H2,26,28,29)
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n/an/a 12.6n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194847
PNG
(US9206184, 28)
Show SMILES COCCOCc1c(CN2CCNCC2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C25H32N6O3S/c1-16-10-17-12-21(35-24(17)20(11-16)33-3)22-18(14-34-9-8-32-2)19(13-30-6-4-27-5-7-30)31-23(22)25(26)28-15-29-31/h10-12,15,27H,4-9,13-14H2,1-3H3,(H2,26,28,29)
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n/an/a 9.70n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194848
PNG
(US9206184, 29)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COCC(F)(F)F)c(CN2CCNCC2)n2ncnc(N)c12
Show InChI InChI=1S/C24H27F3N6O2S/c1-14-7-15-9-19(36-22(15)18(8-14)34-2)20-16(11-35-12-24(25,26)27)17(10-32-5-3-29-4-6-32)33-21(20)23(28)30-13-31-33/h7-9,13,29H,3-6,10-12H2,1-2H3,(H2,28,30,31)
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n/an/a 2.5n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194849
PNG
(US9206184, 30)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COCCN)c(CN2CCNCC2)n2ncnc(N)c12
Show InChI InChI=1S/C24H31N7O2S/c1-15-9-16-11-20(34-23(16)19(10-15)32-2)21-17(13-33-8-3-25)18(12-30-6-4-27-5-7-30)31-22(21)24(26)28-14-29-31/h9-11,14,27H,3-8,12-13,25H2,1-2H3,(H2,26,28,29)
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n/an/a 6.40n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194850
PNG
(US9206184, 31)
Show SMILES COC(=O)COCc1c(CN2CCNCC2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C25H30N6O4S/c1-15-8-16-10-20(36-24(16)19(9-15)33-2)22-17(12-35-13-21(32)34-3)18(11-30-6-4-27-5-7-30)31-23(22)25(26)28-14-29-31/h8-10,14,27H,4-7,11-13H2,1-3H3,(H2,26,28,29)
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n/an/a 13.3n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194851
PNG
(US9206184, 32)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COCC(O)=O)c(CN2CCNCC2)n2ncnc(N)c12
Show InChI InChI=1S/C24H28N6O4S/c1-14-7-15-9-19(35-23(15)18(8-14)33-2)21-16(11-34-12-20(31)32)17(10-29-5-3-26-4-6-29)30-22(21)24(25)27-13-28-30/h7-9,13,26H,3-6,10-12H2,1-2H3,(H,31,32)(H2,25,27,28)
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n/an/a 52.3n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194852
PNG
(US9206184, 33)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COCC(N)=O)c(CN2CCNCC2)n2ncnc(N)c12
Show InChI InChI=1S/C24H29N7O3S/c1-14-7-15-9-19(35-23(15)18(8-14)33-2)21-16(11-34-12-20(25)32)17(10-30-5-3-27-4-6-30)31-22(21)24(26)28-13-29-31/h7-9,13,27H,3-6,10-12H2,1-2H3,(H2,25,32)(H2,26,28,29)
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US Patent
n/an/a 7.20n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194853
PNG
(US9206184, 34)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COCC(N)=O)c(CN2CCN(CC2)C(C)=O)n2ncnc(N)c12
Show InChI InChI=1S/C26H31N7O4S/c1-15-8-17-10-21(38-25(17)20(9-15)36-3)23-18(12-37-13-22(27)35)19(33-24(23)26(28)29-14-30-33)11-31-4-6-32(7-5-31)16(2)34/h8-10,14H,4-7,11-13H2,1-3H3,(H2,27,35)(H2,28,29,30)
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n/an/a 10.5n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194854
PNG
(US9206184, 35)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(COc2ccccc2)c(CN2CCNCC2)n2ncnc(N)c12
Show InChI InChI=1S/C28H30N6O2S/c1-18-12-19-14-24(37-27(19)23(13-18)35-2)25-21(16-36-20-6-4-3-5-7-20)22(15-33-10-8-30-9-11-33)34-26(25)28(29)31-17-32-34/h3-7,12-14,17,30H,8-11,15-16H2,1-2H3,(H2,29,31,32)
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n/an/a 65.4n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194855
PNG
(US9206184, 36)
Show SMILES CNCc1c(CN2CCNCC2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C23H29N7OS/c1-14-8-15-10-19(32-22(15)18(9-14)31-3)20-16(11-25-2)17(12-29-6-4-26-5-7-29)30-21(20)23(24)27-13-28-30/h8-10,13,25-26H,4-7,11-12H2,1-3H3,(H2,24,27,28)
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n/an/a 9.80n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194856
PNG
(US9206184, 37)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CN(C)C)c(CN2CCNCC2)n2ncnc(N)c12
Show InChI InChI=1S/C24H31N7OS/c1-15-9-16-11-20(33-23(16)19(10-15)32-4)21-17(12-29(2)3)18(13-30-7-5-26-6-8-30)31-22(21)24(25)27-14-28-31/h9-11,14,26H,5-8,12-13H2,1-4H3,(H2,25,27,28)
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n/an/a 34.6n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194857
PNG
(US9206184, 38)
Show SMILES CCNCc1c(CN2CCNCC2)n2ncnc(N)c2c1-c1cc2cc(C)cc(OC)c2s1
Show InChI InChI=1S/C24H31N7OS/c1-4-26-12-17-18(13-30-7-5-27-6-8-30)31-22(24(25)28-14-29-31)21(17)20-11-16-9-15(2)10-19(32-3)23(16)33-20/h9-11,14,26-27H,4-8,12-13H2,1-3H3,(H2,25,28,29)
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n/an/a 18.8n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
Fibroblast growth factor receptor 3


(Homo sapiens (Human))
BDBM194858
PNG
(US9206184, 39)
Show SMILES COc1cc(C)cc2cc(sc12)-c1c(CNCCO)c(CN2CCNCC2)n2ncnc(N)c12
Show InChI InChI=1S/C24H31N7O2S/c1-15-9-16-11-20(34-23(16)19(10-15)33-2)21-17(12-27-5-8-32)18(13-30-6-3-26-4-7-30)31-22(21)24(25)28-14-29-31/h9-11,14,26-27,32H,3-8,12-13H2,1-2H3,(H2,25,28,29)
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n/an/a 4.90n/an/an/an/a7.022



BAYER INTELLECTUAL PROPERTY GmbH

US Patent


Assay Description
For the assay, 50 nl of each stock solution of the test compound in DMSO was pipetted into a black, low-volume 384-well microtiter plate (Greiner Bio...


US Patent US9206184 (2015)


BindingDB Entry DOI: 10.7270/Q2SN07SH
More data for this
Ligand-Target Pair
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