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Compile Data Set for Download or QSAR

Found 1183 hits Enz. Inhib. hit(s) with Target = 'Glucokinase'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glucokinase


(Mus musculus (Mouse))
BDBM239065
PNG
(US9409900, 6)
Show SMILES CS(=O)(=O)c1ccc(Oc2ccc(Nc3ccc(cn3)C(O)=O)cc2CN2CCCC2=O)cn1
Show InChI InChI=1S/C23H22N4O6S/c1-34(31,32)21-9-6-18(13-25-21)33-19-7-5-17(11-16(19)14-27-10-2-3-22(27)28)26-20-8-4-15(12-24-20)23(29)30/h4-9,11-13H,2-3,10,14H2,1H3,(H,24,26)(H,29,30)
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n/an/an/an/a 2.00E+3n/an/a7.1n/a



FUJIAN HAIXI PHARMACEUTICALS, INC.; BETTA PHARMACUETICALS CO., LTD.

US Patent


Assay Description
The final assay volume was 200 uL and the final buffer conditions used in this assay were as follows: 25 mM HEPES, 5 mM glucose, 1 mM ATP, 2 mM MgCl2...


US Patent US9409900 (2016)


BindingDB Entry DOI: 10.7270/Q2SF2V3P
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus (Mouse))
BDBM239067
PNG
(US9409900, 78)
Show SMILES CN(C)C(=O)c1ccc(Oc2ccc(Nc3ccc(CCC(O)=O)cn3)cc2CN2CCCC2=O)cn1
Show InChI InChI=1S/C27H29N5O5/c1-31(2)27(36)22-9-8-21(16-28-22)37-23-10-7-20(14-19(23)17-32-13-3-4-25(32)33)30-24-11-5-18(15-29-24)6-12-26(34)35/h5,7-11,14-16H,3-4,6,12-13,17H2,1-2H3,(H,29,30)(H,34,35)
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n/an/an/an/a 1.50E+3n/an/a7.1n/a



FUJIAN HAIXI PHARMACEUTICALS, INC.; BETTA PHARMACUETICALS CO., LTD.

US Patent


Assay Description
The final assay volume was 200 uL and the final buffer conditions used in this assay were as follows: 25 mM HEPES, 5 mM glucose, 1 mM ATP, 2 mM MgCl2...


US Patent US9409900 (2016)


BindingDB Entry DOI: 10.7270/Q2SF2V3P
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus (Mouse))
BDBM239068
PNG
(US9409900, 65)
Show SMILES CN(C)C(=O)c1ccc(Oc2ccc(Nc3ccccn3)cc2CN2CCCC2=O)cn1
Show InChI InChI=1S/C24H25N5O3/c1-28(2)24(31)20-10-9-19(15-26-20)32-21-11-8-18(27-22-6-3-4-12-25-22)14-17(21)16-29-13-5-7-23(29)30/h3-4,6,8-12,14-15H,5,7,13,16H2,1-2H3,(H,25,27)
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n/an/an/an/a 5.00E+3n/an/a7.1n/a



FUJIAN HAIXI PHARMACEUTICALS, INC.; BETTA PHARMACUETICALS CO., LTD.

US Patent


Assay Description
The final assay volume was 200 uL and the final buffer conditions used in this assay were as follows: 25 mM HEPES, 5 mM glucose, 1 mM ATP, 2 mM MgCl2...


US Patent US9409900 (2016)


BindingDB Entry DOI: 10.7270/Q2SF2V3P
More data for this
Ligand-Target Pair
Glucokinase


(Mus musculus (Mouse))
BDBM239066
PNG
(US9409900, 13)
Show SMILES Cc1cnc(Nc2ccc(Oc3ccc(nc3)S(C)(=O)=O)c(CN3CCCC3=O)c2)s1
Show InChI InChI=1S/C21H22N4O4S2/c1-14-11-23-21(30-14)24-16-5-7-18(15(10-16)13-25-9-3-4-20(25)26)29-17-6-8-19(22-12-17)31(2,27)28/h5-8,10-12H,3-4,9,13H2,1-2H3,(H,23,24)
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n/an/an/an/a 2.00E+3n/an/a7.1n/a



FUJIAN HAIXI PHARMACEUTICALS, INC.; BETTA PHARMACUETICALS CO., LTD.

US Patent


Assay Description
The final assay volume was 200 uL and the final buffer conditions used in this assay were as follows: 25 mM HEPES, 5 mM glucose, 1 mM ATP, 2 mM MgCl2...


US Patent US9409900 (2016)


BindingDB Entry DOI: 10.7270/Q2SF2V3P
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431731
PNG
(CHEMBL2346751)
Show SMILES Cc1cc(cc(=O)n1[C@@H](CC1CCCC1)C(=O)Nc1ncc(Cl)s1)S(=O)(=O)C1CC1
Show InChI InChI=1S/C20H24ClN3O4S2/c1-12-8-15(30(27,28)14-6-7-14)10-18(25)24(12)16(9-13-4-2-3-5-13)19(26)23-20-22-11-17(21)29-20/h8,10-11,13-14,16H,2-7,9H2,1H3,(H,22,23,26)/t16-/m0/s1
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n/an/an/an/a 160n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431732
PNG
(CHEMBL2346752)
Show SMILES Cc1cc(cc(=O)n1[C@@H](CC1CCCCO1)C(=O)Nc1ncc(Cl)s1)S(=O)(=O)C1CC1
Show InChI InChI=1S/C20H24ClN3O5S2/c1-12-8-15(31(27,28)14-5-6-14)10-18(25)24(12)16(9-13-4-2-3-7-29-13)19(26)23-20-22-11-17(21)30-20/h8,10-11,13-14,16H,2-7,9H2,1H3,(H,22,23,26)/t13?,16-/m0/s1
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n/an/an/an/a 1.20E+3n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431733
PNG
(CHEMBL2346756)
Show SMILES Cc1cc(cc(=O)n1[C@@H](CC1CCCC1)C(=O)Nc1ncc(F)s1)S(=O)(=O)C1CC1
Show InChI InChI=1S/C20H24FN3O4S2/c1-12-8-15(30(27,28)14-6-7-14)10-18(25)24(12)16(9-13-4-2-3-5-13)19(26)23-20-22-11-17(21)29-20/h8,10-11,13-14,16H,2-7,9H2,1H3,(H,22,23,26)/t16-/m0/s1
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n/an/an/an/a 630n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431734
PNG
(CHEMBL2346755)
Show SMILES Cc1cc(cc(=O)n1[C@@H](CC1CCCCO1)C(=O)Nc1ncc(F)s1)S(=O)(=O)C1CCCC1
Show InChI InChI=1S/C22H28FN3O5S2/c1-14-10-17(33(29,30)16-7-2-3-8-16)12-20(27)26(14)18(11-15-6-4-5-9-31-15)21(28)25-22-24-13-19(23)32-22/h10,12-13,15-16,18H,2-9,11H2,1H3,(H,24,25,28)/t15?,18-/m0/s1
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n/an/an/an/a 500n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431735
PNG
(CHEMBL2346754)
Show SMILES Cc1cc(cc(=O)n1[C@@H](CC1CCCCO1)C(=O)Nc1ncc(Cl)s1)S(=O)(=O)C1CCCC1
Show InChI InChI=1S/C22H28ClN3O5S2/c1-14-10-17(33(29,30)16-7-2-3-8-16)12-20(27)26(14)18(11-15-6-4-5-9-31-15)21(28)25-22-24-13-19(23)32-22/h10,12-13,15-16,18H,2-9,11H2,1H3,(H,24,25,28)/t15?,18-/m0/s1
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n/an/an/an/a 160n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431736
PNG
(CHEMBL2346753)
Show SMILES CCCCC(C(=O)Nc1nccs1)n1c(C)cc(cc1=O)S(=O)(=O)C1CCCC1
Show InChI InChI=1S/C20H27N3O4S2/c1-3-4-9-17(19(25)22-20-21-10-11-28-20)23-14(2)12-16(13-18(23)24)29(26,27)15-7-5-6-8-15/h10-13,15,17H,3-9H2,1-2H3,(H,21,22,25)
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n/an/an/an/a 1.60E+3n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431737
PNG
(CHEMBL2346757)
Show SMILES Cc1cc(cc(=O)n1C(CC1CCCCO1)C(=O)Nc1nccs1)S(=O)(=O)C1CCCC1
Show InChI InChI=1S/C22H29N3O5S2/c1-15-12-18(32(28,29)17-7-2-3-8-17)14-20(26)25(15)19(13-16-6-4-5-10-30-16)21(27)24-22-23-9-11-31-22/h9,11-12,14,16-17,19H,2-8,10,13H2,1H3,(H,23,24,27)
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n/an/an/an/a 1.00E+3n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431738
PNG
(CHEMBL2346758)
Show SMILES Cc1cc(cc(=O)n1C(CC1CCCC1)C(=O)Nc1nccs1)S(=O)(=O)C1CCCC1
Show InChI InChI=1S/C22H29N3O4S2/c1-15-12-18(31(28,29)17-8-4-5-9-17)14-20(26)25(15)19(13-16-6-2-3-7-16)21(27)24-22-23-10-11-30-22/h10-12,14,16-17,19H,2-9,13H2,1H3,(H,23,24,27)
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n/an/an/an/a 200n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431739
PNG
(CHEMBL2346759)
Show SMILES Cc1cc(cc(=O)n1C(CC1CC1)C(=O)Nc1nccs1)S(=O)(=O)C1CCCC1
Show InChI InChI=1S/C20H25N3O4S2/c1-13-10-16(29(26,27)15-4-2-3-5-15)12-18(24)23(13)17(11-14-6-7-14)19(25)22-20-21-8-9-28-20/h8-10,12,14-15,17H,2-7,11H2,1H3,(H,21,22,25)
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n/an/an/an/a 1.60E+3n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431740
PNG
(CHEMBL2346760)
Show SMILES CC(C)CC(C(=O)Nc1nccs1)n1c(C)cc(cc1=O)S(=O)(=O)C1CCCC1
Show InChI InChI=1S/C20H27N3O4S2/c1-13(2)10-17(19(25)22-20-21-8-9-28-20)23-14(3)11-16(12-18(23)24)29(26,27)15-6-4-5-7-15/h8-9,11-13,15,17H,4-7,10H2,1-3H3,(H,21,22,25)
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n/an/an/an/a 790n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431741
PNG
(CHEMBL2346761)
Show SMILES Cc1cc(cc(=O)n1[C@@H](CC1CCCCC1)C(=O)Nc1nccs1)S(=O)(=O)C1CCCC1
Show InChI InChI=1S/C23H31N3O4S2/c1-16-13-19(32(29,30)18-9-5-6-10-18)15-21(27)26(16)20(14-17-7-3-2-4-8-17)22(28)25-23-24-11-12-31-23/h11-13,15,17-18,20H,2-10,14H2,1H3,(H,24,25,28)/t20-/m0/s1
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n/an/an/an/a 79n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431742
PNG
(CHEMBL2346762)
Show SMILES CCS(=O)(=O)c1cc(C)n([C@@H](CC2CCCCC2)C(=O)Nc2nccs2)c(=O)c1
Show InChI InChI=1S/C20H27N3O4S2/c1-3-29(26,27)16-11-14(2)23(18(24)13-16)17(12-15-7-5-4-6-8-15)19(25)22-20-21-9-10-28-20/h9-11,13,15,17H,3-8,12H2,1-2H3,(H,21,22,25)/t17-/m0/s1
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n/an/an/an/a 2.00E+3n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431743
PNG
(CHEMBL2346763)
Show SMILES Cc1cc(cc(=O)n1[C@@H](CC1CCCCC1)C(=O)Nc1nccs1)S(C)(=O)=O
Show InChI InChI=1S/C19H25N3O4S2/c1-13-10-15(28(2,25)26)12-17(23)22(13)16(11-14-6-4-3-5-7-14)18(24)21-19-20-8-9-27-19/h8-10,12,14,16H,3-7,11H2,1-2H3,(H,20,21,24)/t16-/m0/s1
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n/an/an/an/a 6.30E+3n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431744
PNG
(CHEMBL2346764)
Show SMILES CC(C)S(=O)(=O)N1CCN([C@@H](CC2CCCCC2)C(=O)Nc2nccs2)C(=O)C1
Show InChI InChI=1S/C19H30N4O4S2/c1-14(2)29(26,27)22-9-10-23(17(24)13-22)16(12-15-6-4-3-5-7-15)18(25)21-19-20-8-11-28-19/h8,11,14-16H,3-7,9-10,12-13H2,1-2H3,(H,20,21,25)/t16-/m0/s1
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n/an/an/an/a 1.00E+3n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431745
PNG
(CHEMBL2346875)
Show SMILES O=C(Nc1nccs1)[C@H](CC1CCCCC1)N1CCN(CC1=O)S(=O)(=O)Cc1ccccc1
Show InChI InChI=1S/C23H30N4O4S2/c28-21-16-26(33(30,31)17-19-9-5-2-6-10-19)12-13-27(21)20(15-18-7-3-1-4-8-18)22(29)25-23-24-11-14-32-23/h2,5-6,9-11,14,18,20H,1,3-4,7-8,12-13,15-17H2,(H,24,25,29)/t20-/m0/s1
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n/an/an/an/a 400n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431746
PNG
(CHEMBL2346877)
Show SMILES O=C(Nc1nccs1)[C@H](CC1CCCCC1)N1CCN(CC1=O)S(=O)(=O)c1ccco1
Show InChI InChI=1S/C20H26N4O5S2/c25-17-14-23(31(27,28)18-7-4-11-29-18)9-10-24(17)16(13-15-5-2-1-3-6-15)19(26)22-20-21-8-12-30-20/h4,7-8,11-12,15-16H,1-3,5-6,9-10,13-14H2,(H,21,22,26)/t16-/m0/s1
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n/an/an/an/a 160n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431747
PNG
(CHEMBL2346876)
Show SMILES Cc1ccc(c(F)c1)S(=O)(=O)N1CCN([C@@H](CC2CCCCC2)C(=O)Nc2nccs2)C(=O)C1
Show InChI InChI=1S/C23H29FN4O4S2/c1-16-7-8-20(18(24)13-16)34(31,32)27-10-11-28(21(29)15-27)19(14-17-5-3-2-4-6-17)22(30)26-23-25-9-12-33-23/h7-9,12-13,17,19H,2-6,10-11,14-15H2,1H3,(H,25,26,30)/t19-/m0/s1
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n/an/an/an/a 250n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431748
PNG
(CHEMBL2346667)
Show SMILES Cc1cccc(c1)S(=O)(=O)N1CCN([C@@H](CC2CCCCC2)C(=O)Nc2nccs2)C(=O)C1
Show InChI InChI=1S/C23H30N4O4S2/c1-17-6-5-9-19(14-17)33(30,31)26-11-12-27(21(28)16-26)20(15-18-7-3-2-4-8-18)22(29)25-23-24-10-13-32-23/h5-6,9-10,13-14,18,20H,2-4,7-8,11-12,15-16H2,1H3,(H,24,25,29)/t20-/m0/s1
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n/an/an/an/a 200n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431749
PNG
(CHEMBL2346879)
Show SMILES Fc1cc(F)cc(c1)S(=O)(=O)N1CCN([C@@H](CC2CCCCC2)C(=O)Nc2nccs2)C(=O)C1
Show InChI InChI=1S/C22H26F2N4O4S2/c23-16-11-17(24)13-18(12-16)34(31,32)27-7-8-28(20(29)14-27)19(10-15-4-2-1-3-5-15)21(30)26-22-25-6-9-33-22/h6,9,11-13,15,19H,1-5,7-8,10,14H2,(H,25,26,30)/t19-/m0/s1
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n/an/an/an/a 200n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431750
PNG
(CHEMBL2346878)
Show SMILES Clc1cccc(c1)S(=O)(=O)N1CCN([C@@H](CC2CCCCC2)C(=O)Nc2nccs2)C(=O)C1
Show InChI InChI=1S/C22H27ClN4O4S2/c23-17-7-4-8-18(14-17)33(30,31)26-10-11-27(20(28)15-26)19(13-16-5-2-1-3-6-16)21(29)25-22-24-9-12-32-22/h4,7-9,12,14,16,19H,1-3,5-6,10-11,13,15H2,(H,24,25,29)/t19-/m0/s1
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n/an/an/an/a 310n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431751
PNG
(CHEMBL2346880)
Show SMILES CS(=O)(=O)N1CCN([C@@H](CC2CCCCO2)C(=O)Nc2ncc(Cl)s2)C(=O)C1
Show InChI InChI=1S/C16H23ClN4O5S2/c1-28(24,25)20-5-6-21(14(22)10-20)12(8-11-4-2-3-7-26-11)15(23)19-16-18-9-13(17)27-16/h9,11-12H,2-8,10H2,1H3,(H,18,19,23)/t11?,12-/m0/s1
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n/an/an/an/a 2.00E+3n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431752
PNG
(CHEMBL2346881)
Show SMILES Clc1cnc(NC(=O)[C@H](CC2CCCCO2)N2CCN(CC2=O)S(=O)(=O)C2CC2)s1
Show InChI InChI=1S/C18H25ClN4O5S2/c19-15-10-20-18(29-15)21-17(25)14(9-12-3-1-2-8-28-12)23-7-6-22(11-16(23)24)30(26,27)13-4-5-13/h10,12-14H,1-9,11H2,(H,20,21,25)/t12?,14-/m0/s1
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n/an/an/an/a 790n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431753
PNG
(CHEMBL2346882)
Show SMILES O=C(Nc1nccs1)[C@H](CC1CCCCC1)N1CCN(CC1=O)S(=O)(=O)C1CCCC1
Show InChI InChI=1S/C21H32N4O4S2/c26-19-15-24(31(28,29)17-8-4-5-9-17)11-12-25(19)18(14-16-6-2-1-3-7-16)20(27)23-21-22-10-13-30-21/h10,13,16-18H,1-9,11-12,14-15H2,(H,22,23,27)/t18-/m0/s1
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n/an/an/an/a 63n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431754
PNG
(CHEMBL2346883)
Show SMILES O=C(Nc1nccs1)C(CC1CCCCC1)N1CCN(CC1=O)S(=O)(=O)C1CC1
Show InChI InChI=1S/C19H28N4O4S2/c24-17-13-22(29(26,27)15-6-7-15)9-10-23(17)16(12-14-4-2-1-3-5-14)18(25)21-19-20-8-11-28-19/h8,11,14-16H,1-7,9-10,12-13H2,(H,20,21,25)
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n/an/an/an/a 250n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431755
PNG
(CHEMBL2346884)
Show SMILES CS(=O)(=O)N1CCN(C(CC2CCCCC2)C(=O)Nc2nccs2)C(=O)C1
Show InChI InChI=1S/C17H26N4O4S2/c1-27(24,25)20-8-9-21(15(22)12-20)14(11-13-5-3-2-4-6-13)16(23)19-17-18-7-10-26-17/h7,10,13-14H,2-6,8-9,11-12H2,1H3,(H,18,19,23)
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n/an/an/an/a 1.60E+3n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431756
PNG
(CHEMBL2346885)
Show SMILES O=C(Nc1nccs1)[C@H](CC1CCCC1)n1cnc2cc(ccc2c1=O)S(=O)(=O)C1CC1
Show InChI InChI=1S/C22H24N4O4S2/c27-20(25-22-23-9-10-31-22)19(11-14-3-1-2-4-14)26-13-24-18-12-16(7-8-17(18)21(26)28)32(29,30)15-5-6-15/h7-10,12-15,19H,1-6,11H2,(H,23,25,27)/t19-/m0/s1
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n/an/an/an/a 2.00E+3n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431757
PNG
(CHEMBL2346886)
Show SMILES CCS(=O)(=O)c1ccc2c(c1)ncn([C@@H](CC1CCCCO1)C(=O)Nc1ncc(F)s1)c2=O
Show InChI InChI=1S/C21H23FN4O5S2/c1-2-33(29,30)14-6-7-15-16(10-14)24-12-26(20(15)28)17(9-13-5-3-4-8-31-13)19(27)25-21-23-11-18(22)32-21/h6-7,10-13,17H,2-5,8-9H2,1H3,(H,23,25,27)/t13?,17-/m0/s1
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n/an/an/an/a 5.00E+3n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431758
PNG
(CHEMBL2346887)
Show SMILES CCS(=O)(=O)c1ccc2c(c1)ncn([C@@H](CC1CCCCC1)C(=O)Nc1ncc(F)s1)c2=O
Show InChI InChI=1S/C22H25FN4O4S2/c1-2-33(30,31)15-8-9-16-17(11-15)25-13-27(21(16)29)18(10-14-6-4-3-5-7-14)20(28)26-22-24-12-19(23)32-22/h8-9,11-14,18H,2-7,10H2,1H3,(H,24,26,28)/t18-/m0/s1
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n/an/an/an/a 630n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431759
PNG
(CHEMBL2346888)
Show SMILES Clc1cnc(NC(=O)[C@H](CC2CCCCC2)n2cnc3cc(ccc3c2=O)S(=O)(=O)C2CCCC2)s1
Show InChI InChI=1S/C25H29ClN4O4S2/c26-22-14-27-25(35-22)29-23(31)21(12-16-6-2-1-3-7-16)30-15-28-20-13-18(10-11-19(20)24(30)32)36(33,34)17-8-4-5-9-17/h10-11,13-17,21H,1-9,12H2,(H,27,29,31)/t21-/m0/s1
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n/an/an/an/a 400n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431760
PNG
(CHEMBL2346892)
Show SMILES Fc1cnc(NC(=O)[C@H](CC2CCCCC2)n2cnc3cc(ccc3c2=O)S(=O)(=O)C2CCCC2)s1
Show InChI InChI=1S/C25H29FN4O4S2/c26-22-14-27-25(35-22)29-23(31)21(12-16-6-2-1-3-7-16)30-15-28-20-13-18(10-11-19(20)24(30)32)36(33,34)17-8-4-5-9-17/h10-11,13-17,21H,1-9,12H2,(H,27,29,31)/t21-/m0/s1
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n/an/an/an/a 310n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431761
PNG
(CHEMBL2346891)
Show SMILES CNC(=O)c1ccc2c(c1)ncn([C@@H](CC1CCCCC1)C(=O)Nc1ncc(Cl)s1)c2=O
Show InChI InChI=1S/C22H24ClN5O3S/c1-24-19(29)14-7-8-15-16(10-14)26-12-28(21(15)31)17(9-13-5-3-2-4-6-13)20(30)27-22-25-11-18(23)32-22/h7-8,10-13,17H,2-6,9H2,1H3,(H,24,29)(H,25,27,30)/t17-/m0/s1
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n/an/an/an/a 79n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431762
PNG
(CHEMBL2346890)
Show SMILES Cc1ccc2ncn([C@@H](CC3CCCCC3)C(=O)Nc3nccs3)c(=O)c2c1
Show InChI InChI=1S/C21H24N4O2S/c1-14-7-8-17-16(11-14)20(27)25(13-23-17)18(12-15-5-3-2-4-6-15)19(26)24-21-22-9-10-28-21/h7-11,13,15,18H,2-6,12H2,1H3,(H,22,24,26)/t18-/m0/s1
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n/an/an/an/a 2.50E+3n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431763
PNG
(CHEMBL2346889)
Show SMILES Fc1ccc2ncn([C@@H](CC3CCCCC3)C(=O)Nc3nccs3)c(=O)c2c1
Show InChI InChI=1S/C20H21FN4O2S/c21-14-6-7-16-15(11-14)19(27)25(12-23-16)17(10-13-4-2-1-3-5-13)18(26)24-20-22-8-9-28-20/h6-9,11-13,17H,1-5,10H2,(H,22,24,26)/t17-/m0/s1
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n/an/an/an/a 4.00E+3n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431764
PNG
(CHEMBL2346893)
Show SMILES Clc1ccc2ncn(C(CC3CCCCC3)C(=O)Nc3nccs3)c(=O)c2c1
Show InChI InChI=1S/C20H21ClN4O2S/c21-14-6-7-16-15(11-14)19(27)25(12-23-16)17(10-13-4-2-1-3-5-13)18(26)24-20-22-8-9-28-20/h6-9,11-13,17H,1-5,10H2,(H,22,24,26)
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n/an/an/an/a 2.00E+3n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431765
PNG
(CHEMBL2346894)
Show SMILES Clc1cnc(NC(=O)C(CC2CCCCO2)n2cnc3cc(ccc3c2=O)C(=O)NC2CC2)s1
Show InChI InChI=1S/C23H24ClN5O4S/c24-19-11-25-23(34-19)28-21(31)18(10-15-3-1-2-8-33-15)29-12-26-17-9-13(4-7-16(17)22(29)32)20(30)27-14-5-6-14/h4,7,9,11-12,14-15,18H,1-3,5-6,8,10H2,(H,27,30)(H,25,28,31)
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n/an/an/an/a 1.20E+3n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431766
PNG
(CHEMBL2346898)
Show SMILES Clc1cnc(NC(=O)C(CC2CCCCC2)n2cnc3cc(ccc3c2=O)C(=O)NC2CC2)s1
Show InChI InChI=1S/C24H26ClN5O3S/c25-20-12-26-24(34-20)29-22(32)19(10-14-4-2-1-3-5-14)30-13-27-18-11-15(6-9-17(18)23(30)33)21(31)28-16-7-8-16/h6,9,11-14,16,19H,1-5,7-8,10H2,(H,28,31)(H,26,29,32)
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n/an/an/an/a 120n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431767
PNG
(CHEMBL2346897)
Show SMILES CS(=O)(=O)c1ccc2c(c1)ncn([C@@H](CC1CCCCC1)C(=O)Nc1nccs1)c2=O
Show InChI InChI=1S/C21H24N4O4S2/c1-31(28,29)15-7-8-16-17(12-15)23-13-25(20(16)27)18(11-14-5-3-2-4-6-14)19(26)24-21-22-9-10-30-21/h7-10,12-14,18H,2-6,11H2,1H3,(H,22,24,26)/t18-/m0/s1
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n/an/an/an/a 500n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431768
PNG
(CHEMBL2346896)
Show SMILES O=C(Nc1nccs1)[C@H](CC1CCCCC1)n1cnc2ccccc2c1=O
Show InChI InChI=1S/C20H22N4O2S/c25-18(23-20-21-10-11-27-20)17(12-14-6-2-1-3-7-14)24-13-22-16-9-5-4-8-15(16)19(24)26/h4-5,8-11,13-14,17H,1-3,6-7,12H2,(H,21,23,25)/t17-/m0/s1
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n/an/an/an/a 1.00E+4n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431769
PNG
(CHEMBL2346895)
Show SMILES CS(=O)(=O)c1ccc2c(c1)[nH]c(=O)n(C(CC1CCCCC1)C(=O)Nc1ncc(Cl)s1)c2=O
Show InChI InChI=1S/C21H23ClN4O5S2/c1-33(30,31)13-7-8-14-15(10-13)24-21(29)26(19(14)28)16(9-12-5-3-2-4-6-12)18(27)25-20-23-11-17(22)32-20/h7-8,10-12,16H,2-6,9H2,1H3,(H,24,29)(H,23,25,27)
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n/an/an/an/a 630n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431770
PNG
(CHEMBL2346899)
Show SMILES Fc1ccc2[nH]c(=O)n([C@@H](CC3CCCCC3)C(=O)Nc3nccs3)c(=O)c2c1
Show InChI InChI=1S/C20H21FN4O3S/c21-13-6-7-15-14(11-13)18(27)25(20(28)23-15)16(10-12-4-2-1-3-5-12)17(26)24-19-22-8-9-29-19/h6-9,11-12,16H,1-5,10H2,(H,23,28)(H,22,24,26)/t16-/m0/s1
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n/an/an/an/a 3.10E+3n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431771
PNG
(CHEMBL2346902)
Show SMILES COc1ccc2[nH]c(=O)n([C@@H](CC3CCCCC3)C(=O)Nc3nccs3)c(=O)c2c1
Show InChI InChI=1S/C21H24N4O4S/c1-29-14-7-8-16-15(12-14)19(27)25(21(28)23-16)17(11-13-5-3-2-4-6-13)18(26)24-20-22-9-10-30-20/h7-10,12-13,17H,2-6,11H2,1H3,(H,23,28)(H,22,24,26)/t17-/m0/s1
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n/an/an/an/a 1.00E+4n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431772
PNG
(CHEMBL2346901)
Show SMILES Clc1ccc2c(c1)[nH]c(=O)n([C@@H](CC1CCCCC1)C(=O)Nc1nccs1)c2=O
Show InChI InChI=1S/C20H21ClN4O3S/c21-13-6-7-14-15(11-13)23-20(28)25(18(14)27)16(10-12-4-2-1-3-5-12)17(26)24-19-22-8-9-29-19/h6-9,11-12,16H,1-5,10H2,(H,23,28)(H,22,24,26)/t16-/m0/s1
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n/an/an/an/a 2.00E+3n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431773
PNG
(CHEMBL2346909)
Show SMILES CC(C)CC(N1C(=O)c2ccccc2C1=O)C(=O)Nc1nccs1
Show InChI InChI=1S/C17H17N3O3S/c1-10(2)9-13(14(21)19-17-18-7-8-24-17)20-15(22)11-5-3-4-6-12(11)16(20)23/h3-8,10,13H,9H2,1-2H3,(H,18,19,21)
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n/an/an/an/a 1.00E+4n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431774
PNG
(CHEMBL2346907)
Show SMILES CC(C)CC(N1Cc2ccccc2C1)C(=O)Nc1nccs1
Show InChI InChI=1S/C17H21N3OS/c1-12(2)9-15(16(21)19-17-18-7-8-22-17)20-10-13-5-3-4-6-14(13)11-20/h3-8,12,15H,9-11H2,1-2H3,(H,18,19,21)
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n/an/an/an/a>1.00E+5n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50431775
PNG
(CHEMBL2346908)
Show SMILES CC(C)CC(N1CCN(CC1)S(C)(=O)=O)C(=O)Nc1nccs1
Show InChI InChI=1S/C14H24N4O3S2/c1-11(2)10-12(13(19)16-14-15-4-9-22-14)17-5-7-18(8-6-17)23(3,20)21/h4,9,11-12H,5-8,10H2,1-3H3,(H,15,16,19)
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n/an/an/an/a>1.00E+5n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
Hexokinase type IV


(Homo sapiens (Human))
BDBM50346020
PNG
((2R)-3-Cyclopentyl-2-(4-methanesulfonylphenyl)-N-t...)
Show SMILES CS(=O)(=O)c1ccc(cc1)[C@@H](CC1CCCC1)C(=O)Nc1nccs1
Show InChI InChI=1S/C18H22N2O3S2/c1-25(22,23)15-8-6-14(7-9-15)16(12-13-4-2-3-5-13)17(21)20-18-19-10-11-24-18/h6-11,13,16H,2-5,12H2,1H3,(H,19,20,21)/t16-/m1/s1
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n/an/an/an/a 500n/an/an/an/a



Takeda California

Curated by ChEMBL


Assay Description
Activation of glucokinase (unknown origin)


Bioorg Med Chem Lett 23: 2166-71 (2013)


Article DOI: 10.1016/j.bmcl.2013.01.093
BindingDB Entry DOI: 10.7270/Q2W09791
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
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