BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 744 hits Enz. Inhib. hit(s) with Target = 'Glycogen Phosphorylase (PYGM)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM34110
PNG
(glucopyranosylidene-spiro-isoxazoline, 4e)
Show SMILES OC[C@H]1O[C@@]2(CC(=NO2)c2ccc3ccccc3c2)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C18H19NO6/c20-9-14-15(21)16(22)17(23)18(24-14)8-13(19-25-18)12-6-5-10-3-1-2-4-11(10)7-12/h1-7,14-17,20-23H,8-9H2/t14-,15-,16+,17-,18-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
630 -36.0n/an/an/an/an/a6.830



Universite de Lyon



Assay Description
Phosphorylase activity was measured in the direction of glycogen synthesis by the release of orthophosphate from Glc-1-P. The enzyme was assayed in g...


Bioorg Med Chem 17: 7368-80 (2009)


Article DOI: 10.1016/j.bmc.2009.08.060
BindingDB Entry DOI: 10.7270/Q28P5XV8
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM34106
PNG
(glucopyranosylidene-spiro-isoxazoline, 4a)
Show SMILES COc1ccc(cc1)C1=NO[C@@]2(C1)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O
Show InChI InChI=1S/C15H19NO7/c1-21-9-4-2-8(3-5-9)10-6-15(23-16-10)14(20)13(19)12(18)11(7-17)22-15/h2-5,11-14,17-20H,6-7H2,1H3/t11-,12-,13+,14-,15-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
PDB
UniChem

Similars

PDB
Article
PubMed
6.60E+3 -30.1n/an/an/an/an/a6.830



Universite de Lyon



Assay Description
Phosphorylase activity was measured in the direction of glycogen synthesis by the release of orthophosphate from Glc-1-P. The enzyme was assayed in g...


Bioorg Med Chem 17: 7368-80 (2009)


Article DOI: 10.1016/j.bmc.2009.08.060
BindingDB Entry DOI: 10.7270/Q28P5XV8
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM34107
PNG
(glucopyranosylidene-spiro-isoxazoline, 4b)
Show SMILES Cc1ccc(cc1)C1=NO[C@@]2(C1)O[C@H](CO)[C@@H](O)[C@H](O)[C@H]2O
Show InChI InChI=1S/C15H19NO6/c1-8-2-4-9(5-3-8)10-6-15(22-16-10)14(20)13(19)12(18)11(7-17)21-15/h2-5,11-14,17-20H,6-7H2,1H3/t11-,12-,13+,14-,15-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
7.90E+3 -29.6n/an/an/an/an/a6.830



Universite de Lyon



Assay Description
Phosphorylase activity was measured in the direction of glycogen synthesis by the release of orthophosphate from Glc-1-P. The enzyme was assayed in g...


Bioorg Med Chem 17: 7368-80 (2009)


Article DOI: 10.1016/j.bmc.2009.08.060
BindingDB Entry DOI: 10.7270/Q28P5XV8
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM34108
PNG
(glucopyranosylidene-spiro-isoxazoline, 4c)
Show SMILES OC[C@H]1O[C@@]2(CC(=NO2)c2ccccc2)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C14H17NO6/c16-7-10-11(17)12(18)13(19)14(20-10)6-9(15-21-14)8-4-2-1-3-5-8/h1-5,10-13,16-19H,6-7H2/t10-,11-,12+,13-,14-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
DrugBank
PC cid
PC sid
PDB
UniChem

Similars

PDB
Article
PubMed
1.96E+4 -27.3n/an/an/an/an/a6.830



Universite de Lyon



Assay Description
Phosphorylase activity was measured in the direction of glycogen synthesis by the release of orthophosphate from Glc-1-P. The enzyme was assayed in g...


Bioorg Med Chem 17: 7368-80 (2009)


Article DOI: 10.1016/j.bmc.2009.08.060
BindingDB Entry DOI: 10.7270/Q28P5XV8
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM34109
PNG
(glucopyranosylidene-spiro-isoxazoline, 4d)
Show SMILES OC[C@H]1O[C@@]2(CC(=NO2)c2ccc(cc2)[N+]([O-])=O)[C@H](O)[C@@H](O)[C@@H]1O
Show InChI InChI=1S/C14H16N2O8/c17-6-10-11(18)12(19)13(20)14(23-10)5-9(15-24-14)7-1-3-8(4-2-7)16(21)22/h1-4,10-13,17-20H,5-6H2/t10-,11-,12+,13-,14-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
9.25E+4 -23.4n/an/an/an/an/a6.830



Universite de Lyon



Assay Description
Phosphorylase activity was measured in the direction of glycogen synthesis by the release of orthophosphate from Glc-1-P. The enzyme was assayed in g...


Bioorg Med Chem 17: 7368-80 (2009)


Article DOI: 10.1016/j.bmc.2009.08.060
BindingDB Entry DOI: 10.7270/Q28P5XV8
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM35331
PNG
(2-oxo-1,2-dihydropyridin-3-yl amide derivative, 7t)
Show SMILES Clc1ccc(CNC(=O)Cn2cccc(NCc3ccccc3)c2=O)cc1Cl
Show InChI InChI=1S/C21H19Cl2N3O2/c22-17-9-8-16(11-18(17)23)13-25-20(27)14-26-10-4-7-19(21(26)28)24-12-15-5-2-1-3-6-15/h1-11,24H,12-14H2,(H,25,27)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 6.30E+3n/an/an/an/a7.222



Griffith University



Assay Description
RMGPa (Rabbit Muscle Glycogen Phosphorylase a) activity was measured in the direction of glycogen synthesis by the formation of inorganic phosphate f...


Bioorg Med Chem 17: 4724-33 (2009)


Article DOI: 10.1016/j.bmc.2009.04.049
BindingDB Entry DOI: 10.7270/Q2PR7TBG
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM35332
PNG
(2-oxo-1,2-dihydropyridin-3-yl amide derivative, 7u)
Show SMILES OC[C@H](Cc1ccccc1)NC(=O)Cn1cccc(NCc2ccccc2)c1=O
Show InChI InChI=1S/C23H25N3O3/c27-17-20(14-18-8-3-1-4-9-18)25-22(28)16-26-13-7-12-21(23(26)29)24-15-19-10-5-2-6-11-19/h1-13,20,24,27H,14-17H2,(H,25,28)/t20-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.222



Griffith University



Assay Description
RMGPa (Rabbit Muscle Glycogen Phosphorylase a) activity was measured in the direction of glycogen synthesis by the formation of inorganic phosphate f...


Bioorg Med Chem 17: 4724-33 (2009)


Article DOI: 10.1016/j.bmc.2009.04.049
BindingDB Entry DOI: 10.7270/Q2PR7TBG
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM35333
PNG
(2-oxo-1,2-dihydropyridin-3-yl amide derivative, 7v)
Show SMILES OC[C@@H](NC(=O)Cn1cccc(NCc2ccccc2)c1=O)c1ccccc1
Show InChI InChI=1S/C22H23N3O3/c26-16-20(18-10-5-2-6-11-18)24-21(27)15-25-13-7-12-19(22(25)28)23-14-17-8-3-1-4-9-17/h1-13,20,23,26H,14-16H2,(H,24,27)/t20-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.20E+5n/an/an/an/a7.222



Griffith University



Assay Description
RMGPa (Rabbit Muscle Glycogen Phosphorylase a) activity was measured in the direction of glycogen synthesis by the formation of inorganic phosphate f...


Bioorg Med Chem 17: 4724-33 (2009)


Article DOI: 10.1016/j.bmc.2009.04.049
BindingDB Entry DOI: 10.7270/Q2PR7TBG
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM35334
PNG
(2-oxo-1,2-dihydropyridin-3-yl amide derivative, 7w)
Show SMILES O=C(Cn1cccc(NCc2ccccc2)c1=O)NC1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C26H30N4O2/c31-25(28-23-13-16-29(17-14-23)19-22-10-5-2-6-11-22)20-30-15-7-12-24(26(30)32)27-18-21-8-3-1-4-9-21/h1-12,15,23,27H,13-14,16-20H2,(H,28,31)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 8.13E+5n/an/an/an/a7.222



Griffith University



Assay Description
RMGPa (Rabbit Muscle Glycogen Phosphorylase a) activity was measured in the direction of glycogen synthesis by the formation of inorganic phosphate f...


Bioorg Med Chem 17: 4724-33 (2009)


Article DOI: 10.1016/j.bmc.2009.04.049
BindingDB Entry DOI: 10.7270/Q2PR7TBG
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM35335
PNG
(2-oxo-1,2-dihydropyridin-3-yl amide derivative, 7x)
Show SMILES COc1ccccc1CNC(=O)Cn1cccc(NCc2ccccc2)c1=O
Show InChI InChI=1S/C22H23N3O3/c1-28-20-12-6-5-10-18(20)15-24-21(26)16-25-13-7-11-19(22(25)27)23-14-17-8-3-2-4-9-17/h2-13,23H,14-16H2,1H3,(H,24,26)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.08E+5n/an/an/an/a7.222



Griffith University



Assay Description
RMGPa (Rabbit Muscle Glycogen Phosphorylase a) activity was measured in the direction of glycogen synthesis by the formation of inorganic phosphate f...


Bioorg Med Chem 17: 4724-33 (2009)


Article DOI: 10.1016/j.bmc.2009.04.049
BindingDB Entry DOI: 10.7270/Q2PR7TBG
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM35336
PNG
(2-oxo-1,2-dihydropyridin-3-yl amide derivative, 8t)
Show SMILES CC(=O)Nc1cccn(CC(=O)NCc2ccc(Cl)c(Cl)c2)c1=O
Show InChI InChI=1S/C16H15Cl2N3O3/c1-10(22)20-14-3-2-6-21(16(14)24)9-15(23)19-8-11-4-5-12(17)13(18)7-11/h2-7H,8-9H2,1H3,(H,19,23)(H,20,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.72E+5n/an/an/an/a7.222



Griffith University



Assay Description
RMGPa (Rabbit Muscle Glycogen Phosphorylase a) activity was measured in the direction of glycogen synthesis by the formation of inorganic phosphate f...


Bioorg Med Chem 17: 4724-33 (2009)


Article DOI: 10.1016/j.bmc.2009.04.049
BindingDB Entry DOI: 10.7270/Q2PR7TBG
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM35337
PNG
(2-oxo-1,2-dihydropyridin-3-yl amide derivative, 9t)
Show SMILES Clc1ccc(CNC(=O)Cn2cccc(NC(=O)c3ccccc3)c2=O)cc1Cl
Show InChI InChI=1S/C21H17Cl2N3O3/c22-16-9-8-14(11-17(16)23)12-24-19(27)13-26-10-4-7-18(21(26)29)25-20(28)15-5-2-1-3-6-15/h1-11H,12-13H2,(H,24,27)(H,25,28)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.62E+5n/an/an/an/a7.222



Griffith University



Assay Description
RMGPa (Rabbit Muscle Glycogen Phosphorylase a) activity was measured in the direction of glycogen synthesis by the formation of inorganic phosphate f...


Bioorg Med Chem 17: 4724-33 (2009)


Article DOI: 10.1016/j.bmc.2009.04.049
BindingDB Entry DOI: 10.7270/Q2PR7TBG
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23187
PNG
((4aS,6aS,6bR,10S,12aR,12bR,14bS)-10-hydroxy-2,2,6a...)
Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@@]34C)[C@@H]2C1)C(O)=O
Show InChI InChI=1S/C30H48O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21?,22+,23-,27-,28+,29+,30-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.40E+4n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23189
PNG
((4aS,6aS,6bR,10R,12aR,12bR,14bS)-10-hydroxy-2,2,6a...)
Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@@H](O)C(C)(C)C5CC[C@@]34C)[C@@H]2C1)C(O)=O
Show InChI InChI=1S/C30H48O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21?,22+,23+,27-,28+,29+,30-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.10E+4n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23190
PNG
((4aS,6aS,6bR,10R,11R,12aR,12bR,14bS)-10,11-dihydro...)
Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)C5CC[C@@]34C)[C@@H]2C1)C(O)=O
Show InChI InChI=1S/C30H48O4/c1-25(2)12-14-30(24(33)34)15-13-28(6)18(19(30)16-25)8-9-22-27(5)17-20(31)23(32)26(3,4)21(27)10-11-29(22,28)7/h8,19-23,31-32H,9-17H2,1-7H3,(H,33,34)/t19-,20+,21?,22+,23-,27-,28+,29+,30-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.80E+4n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23191
PNG
((4aS,6aS,6bR,10S,11R,12aR,12bR,14bS)-10,11-dihydro...)
Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@@H](O)C(C)(C)C5CC[C@@]34C)[C@@H]2C1)C(O)=O
Show InChI InChI=1S/C30H48O4/c1-25(2)12-14-30(24(33)34)15-13-28(6)18(19(30)16-25)8-9-22-27(5)17-20(31)23(32)26(3,4)21(27)10-11-29(22,28)7/h8,19-23,31-32H,9-17H2,1-7H3,(H,33,34)/t19-,20+,21?,22+,23+,27-,28+,29+,30-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.44E+5n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23192
PNG
((4aS,6aS,6bR,10R,11S,12aR,12bR,14bS)-10,11-dihydro...)
Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@H](O)[C@H](O)C(C)(C)C5CC[C@@]34C)[C@@H]2C1)C(O)=O
Show InChI InChI=1S/C30H48O4/c1-25(2)12-14-30(24(33)34)15-13-28(6)18(19(30)16-25)8-9-22-27(5)17-20(31)23(32)26(3,4)21(27)10-11-29(22,28)7/h8,19-23,31-32H,9-17H2,1-7H3,(H,33,34)/t19-,20-,21?,22+,23-,27-,28+,29+,30-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.40E+4n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23193
PNG
((4aS,6aS,6bR,12aR,12bR,14bS)-2,2,6a,6b,9,9,12a-hep...)
Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CCC(=O)C(C)(C)C5CC[C@@]34C)[C@@H]2C1)C(O)=O
Show InChI InChI=1S/C30H46O3/c1-25(2)14-16-30(24(32)33)17-15-28(6)19(20(30)18-25)8-9-22-27(5)12-11-23(31)26(3,4)21(27)10-13-29(22,28)7/h8,20-22H,9-18H2,1-7H3,(H,32,33)/t20-,21?,22+,27-,28+,29+,30-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.80E+4n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23194
PNG
((2S,3S,4S,5R,6S)-6-{[(3S,6aR,6bS,8aS,11S,12aR,14aR...)
Show SMILES CC1(C)[C@H](CC[C@@]2(C)C1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O)O[C@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O[C@@H]1O[C@@H]([C@@H](O)[C@H](O)[C@H]1O)C(O)=O)C(O)=O
Show InChI InChI=1S/C42H62O16/c1-37(2)21-8-11-42(7)31(20(43)16-18-19-17-39(4,36(53)54)13-12-38(19,3)14-15-41(18,42)6)40(21,5)10-9-22(37)55-35-30(26(47)25(46)29(57-35)33(51)52)58-34-27(48)23(44)24(45)28(56-34)32(49)50/h16,19,21-31,34-35,44-48H,8-15,17H2,1-7H3,(H,49,50)(H,51,52)(H,53,54)/t19-,21?,22-,23-,24-,25-,26-,27+,28-,29-,30+,31+,34-,35-,38+,39-,40-,41+,42+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.22E+5n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23195
PNG
((2S,4aS,6aS,6bR,10S,12aS,12bR,14bR)-10-hydroxy-2,4...)
Show SMILES CC1(C)[C@@H](O)CC[C@@]2(C)C1CC[C@]1(C)[C@@H]2C(=O)C=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O
Show InChI InChI=1S/C30H46O4/c1-25(2)21-8-11-30(7)23(28(21,5)10-9-22(25)32)20(31)16-18-19-17-27(4,24(33)34)13-12-26(19,3)14-15-29(18,30)6/h16,19,21-23,32H,8-15,17H2,1-7H3,(H,33,34)/t19-,21?,22-,23+,26+,27-,28-,29+,30+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 6.60E+4n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23196
PNG
((2S,4aS,6aS,6bR,10S,12aR,12bR,14bR)-10-hydroxy-2,4...)
Show SMILES CC1(C)[C@@H](O)CC[C@@]2(C)C1CC[C@]1(C)[C@@H]2CC=C2[C@@H]3C[C@](C)(CC[C@]3(C)CC[C@@]12C)C(O)=O
Show InChI InChI=1S/C30H48O3/c1-25(2)21-10-13-30(7)22(28(21,5)12-11-23(25)31)9-8-19-20-18-27(4,24(32)33)15-14-26(20,3)16-17-29(19,30)6/h8,20-23,31H,9-18H2,1-7H3,(H,32,33)/t20-,21?,22+,23-,26+,27-,28-,29+,30+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.20E+4n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23197
PNG
((1S,2R,4aS,6aS,6bR,10S,12aR,12bR,14bS)-10-hydroxy-...)
Show SMILES C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O
Show InChI InChI=1S/C30H48O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21?,22-,23+,24+,27+,28-,29-,30+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 9.00E+3n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23198
PNG
((1S,2R,4aS,6aS,6bR,10R,12aR,12bR,14bS)-10-hydroxy-...)
Show SMILES C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@@H](O)C(C)(C)C5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O
Show InChI InChI=1S/C30H48O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-24,31H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21?,22-,23-,24+,27+,28-,29-,30+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.90E+4n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23199
PNG
((1S,2R,4aS,6aS,6bR,10R,11R,12aR,12bR,14bS)-10,11-d...)
Show SMILES C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)C5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O
Show InChI InChI=1S/C30H48O4/c1-17-10-13-30(25(33)34)15-14-28(6)19(23(30)18(17)2)8-9-22-27(5)16-20(31)24(32)26(3,4)21(27)11-12-29(22,28)7/h8,17-18,20-24,31-32H,9-16H2,1-7H3,(H,33,34)/t17-,18+,20-,21?,22-,23+,24+,27+,28-,29-,30+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.00E+4n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23200
PNG
((1S,2R,4aS,6aS,6bR,10S,11R,12aR,12bR,14bS)-10,11-d...)
Show SMILES C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@@H](O)C(C)(C)C5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O
Show InChI InChI=1S/C30H48O4/c1-17-10-13-30(25(33)34)15-14-28(6)19(23(30)18(17)2)8-9-22-27(5)16-20(31)24(32)26(3,4)21(27)11-12-29(22,28)7/h8,17-18,20-24,31-32H,9-16H2,1-7H3,(H,33,34)/t17-,18+,20-,21?,22-,23+,24-,27+,28-,29-,30+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 2.13E+5n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23201
PNG
((1S,2R,4aS,6aS,6bR,10R,11S,12aR,12bR,14bS)-10,11-d...)
Show SMILES C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@H](O)[C@H](O)C(C)(C)C5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O
Show InChI InChI=1S/C30H48O4/c1-17-10-13-30(25(33)34)15-14-28(6)19(23(30)18(17)2)8-9-22-27(5)16-20(31)24(32)26(3,4)21(27)11-12-29(22,28)7/h8,17-18,20-24,31-32H,9-16H2,1-7H3,(H,33,34)/t17-,18+,20+,21?,22-,23+,24+,27+,28-,29-,30+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.16E+5n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23202
PNG
((1S,2R,4aS,6aS,6bR,9R,10R,11R,12aR,12bR,14bS)-10,1...)
Show SMILES C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O
Show InChI InChI=1S/C30H48O5/c1-17-9-12-30(25(34)35)14-13-28(5)19(23(30)18(17)2)7-8-22-26(3)15-20(32)24(33)27(4,16-31)21(26)10-11-29(22,28)6/h7,17-18,20-24,31-33H,8-16H2,1-6H3,(H,34,35)/t17-,18+,20-,21?,22-,23+,24+,26+,27+,28-,29-,30+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.70E+4n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23203
PNG
((1S,2R,4aS,6aS,6bR,12aR,12bR,14bS)-1,2,6a,6b,9,9,1...)
Show SMILES C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CCC(=O)C(C)(C)C5CC[C@@]34C)[C@@H]2[C@H]1C)C(O)=O
Show InChI InChI=1S/C30H46O3/c1-18-10-15-30(25(32)33)17-16-28(6)20(24(30)19(18)2)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h8,18-19,21-22,24H,9-17H2,1-7H3,(H,32,33)/t18-,19+,21?,22-,24+,27+,28-,29-,30+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.70E+4n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23204
PNG
((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl...)
Show SMILES CC1(C)CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@@]34C)[C@@H]2C1)C(=O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C36H58O8/c1-31(2)14-16-36(30(42)44-29-28(41)27(40)26(39)22(19-37)43-29)17-15-34(6)20(21(36)18-31)8-9-24-33(5)12-11-25(38)32(3,4)23(33)10-13-35(24,34)7/h8,21-29,37-41H,9-19H2,1-7H3/t21-,22+,23?,24+,25-,26+,27-,28+,29-,33-,34+,35+,36-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.93E+5n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23205
PNG
((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl...)
Show SMILES C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)C5CC[C@@]34C)[C@@H]2[C@H]1C)C(=O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C36H58O8/c1-19-10-15-36(31(42)44-30-29(41)28(40)27(39)22(18-37)43-30)17-16-34(6)21(26(36)20(19)2)8-9-24-33(5)13-12-25(38)32(3,4)23(33)11-14-35(24,34)7/h8,19-20,22-30,37-41H,9-18H2,1-7H3/t19-,20+,22-,23?,24-,25+,26+,27-,28+,29-,30+,33+,34-,35-,36+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.70E+4n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23206
PNG
((2S,3R,4S,5S,6R)-3,4,5-trihydroxy-6-(hydroxymethyl...)
Show SMILES C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)C(C)(C)C5CC[C@@]34C)[C@@H]2[C@H]1C)C(=O)O[C@@H]1O[C@H](CO)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C36H58O9/c1-18-10-13-36(31(43)45-30-28(41)27(40)26(39)22(17-37)44-30)15-14-34(6)20(25(36)19(18)2)8-9-24-33(5)16-21(38)29(42)32(3,4)23(33)11-12-35(24,34)7/h8,18-19,21-30,37-42H,9-17H2,1-7H3/t18-,19+,21-,22-,23?,24-,25+,26-,27+,28-,29+,30+,33+,34-,35-,36+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.06E+5n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23207
PNG
((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-5-(hydroxymet...)
Show SMILES CC(=C)[C@@H]1CC[C@]2(CO)CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12
Show InChI InChI=1S/C30H50O2/c1-19(2)20-10-15-30(18-31)17-16-28(6)21(25(20)30)8-9-23-27(5)13-12-24(32)26(3,4)22(27)11-14-29(23,28)7/h20-25,31-32H,1,8-18H2,2-7H3/t20-,21+,22-,23+,24-,25+,27-,28+,29+,30+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.70E+4n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23208
PNG
((1R,2R,5S,8R,9R,10R,13R,14R,17S,19R)-17-hydroxy-1,...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)C(C)(C)[C@@H]5CC[C@@]34C)[C@@H]12)C(O)=O
Show InChI InChI=1S/C30H48O3/c1-18(2)19-10-15-30(25(32)33)17-16-28(6)20(24(19)30)8-9-22-27(5)13-12-23(31)26(3,4)21(27)11-14-29(22,28)7/h19-24,31H,1,8-17H2,2-7H3,(H,32,33)/t19-,20+,21-,22+,23-,24+,27-,28+,29+,30-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
KEGG
PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 4.30E+4n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23209
PNG
((1R,2R,5S,8R,9R,10R,13R,14R,17S,18R,19R)-17-hydrox...)
Show SMILES CC(=C)[C@@H]1CC[C@@]2(CC[C@]3(C)[C@H](CC[C@@H]4[C@@]5(C)CC[C@H](O)[C@@](C)(CO)[C@@H]5CC[C@@]34C)[C@@H]12)C(O)=O
Show InChI InChI=1S/C30H48O4/c1-18(2)19-9-14-30(25(33)34)16-15-28(5)20(24(19)30)7-8-22-26(3)12-11-23(32)27(4,17-31)21(26)10-13-29(22,28)6/h19-24,31-32H,1,7-17H2,2-6H3,(H,33,34)/t19-,20+,21+,22+,23-,24+,26-,27-,28+,29+,30-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Patents


Similars

Article
PubMed
n/an/a 1.60E+4n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM10849
PNG
(1,3,7-trimethyl-2,3,6,7-tetrahydro-1H-purine-2,6-d...)
Show SMILES Cn1cnc2n(C)c(=O)n(C)c(=O)c12
Show InChI InChI=1S/C8H10N4O2/c1-10-4-9-6-5(10)7(13)12(3)8(14)11(6)2/h4H,1-3H3
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

CHEMBL
DrugBank
KEGG
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

PDB
Article
PubMed
n/an/a 1.14E+5n/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23210
PNG
((1S,2R,4aS,6aS,6bR,8R,9R,10R,11R,12aR,12bR,14bS)-8...)
Show SMILES C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)C5[C@H](O)C[C@@]34C)[C@@H]2[C@H]1C)C(O)=O
Show InChI InChI=1S/C30H48O6/c1-16-9-10-30(25(35)36)12-11-28(5)18(22(30)17(16)2)7-8-21-26(3)13-20(33)24(34)27(4,15-31)23(26)19(32)14-29(21,28)6/h7,16-17,19-24,31-34H,8-15H2,1-6H3,(H,35,36)/t16-,17+,19-,20-,21-,22+,23?,24+,26-,27+,28-,29-,30+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23211
PNG
((2S,3R,4S,5S,6R)-6-({[(2R,3R,4R,5S,6R)-3,4-dihydro...)
Show SMILES C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]5CC[C@@]34C)[C@@H]2[C@H]1C)C(=O)O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C48H78O19/c1-20-10-13-48(15-14-46(6)23(29(48)21(20)2)8-9-28-44(4)16-24(51)39(60)45(5,19-50)27(44)11-12-47(28,46)7)43(61)67-42-36(58)33(55)31(53)26(65-42)18-62-40-37(59)34(56)38(25(17-49)64-40)66-41-35(57)32(54)30(52)22(3)63-41/h8,20-22,24-42,49-60H,9-19H2,1-7H3/t20-,21+,22+,24-,25-,26-,27-,28-,29+,30+,31-,32-,33+,34-,35-,36-,37-,38-,39+,40-,41+,42+,44+,45+,46-,47-,48+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

KEGG
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
Glycogen phosphorylase, muscle form


(Oryctolagus cuniculus (rabbit))
BDBM23212
PNG
((2S,3R,4S,5S,6R)-6-({[(2R,3R,4R,5S,6R)-3,4-dihydro...)
Show SMILES C[C@@H]1CC[C@@]2(CC[C@]3(C)C(=CC[C@@H]4[C@@]5(C)C[C@@H](O)[C@H](O)[C@@](C)(CO)[C@@H]5[C@H](O)C[C@@]34C)[C@@H]2[C@H]1C)C(=O)O[C@@H]1O[C@H](CO[C@@H]2O[C@H](CO)[C@@H](O[C@@H]3O[C@@H](C)[C@H](O)[C@@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C48H78O20/c1-19-10-11-48(13-12-46(6)22(28(48)20(19)2)8-9-27-44(4)14-24(52)39(61)45(5,18-50)38(44)23(51)15-47(27,46)7)43(62)68-42-35(59)32(56)30(54)26(66-42)17-63-40-36(60)33(57)37(25(16-49)65-40)67-41-34(58)31(55)29(53)21(3)64-41/h8,19-21,23-42,49-61H,9-18H2,1-7H3/t19-,20+,21+,23-,24-,25-,26-,27-,28+,29+,30-,31-,32+,33-,34-,35-,36-,37-,38-,39+,40-,41+,42+,44-,45+,46-,47-,48+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/an/an/an/an/a7.222



China Pharmaceutical University



Assay Description
The activity of the compounds is determined by measuring the inhibitory effect of the compounds in the direction of glycogen synthesis, the conversio...


J Med Chem 51: 3540-54 (2008)


Article DOI: 10.1021/jm8000949
BindingDB Entry DOI: 10.7270/Q2WQ0233
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM34071
PNG
(benzamide derivative, 6)
Show SMILES Cn1ccnc1Sc1cc(C(=O)Nc2nccs2)c(N)cc1F
Show InChI InChI=1S/C14H12FN5OS2/c1-20-4-2-18-14(20)23-11-6-8(10(16)7-9(11)15)12(21)19-13-17-3-5-22-13/h2-7H,16H2,1H3,(H,17,19,21)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
Purchase

DrugBank
MMDB
PC cid
PC sid
PDB
UniChem

Patents


Similars

Article
PubMed
n/an/a 4.39E+4n/an/an/an/a7.222



Shanghai Institutes for Biological Sciences



Assay Description
The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...


Bioorg Med Chem 17: 7301-12 (2009)


Article DOI: 10.1016/j.bmc.2009.08.045
BindingDB Entry DOI: 10.7270/Q2DF6PK0
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM34072
PNG
(benzamide derivative, 12)
Show SMILES Cn1ccnc1Sc1cc(C(=O)Nc2cccc(N)c2)c(N)cc1F
Show InChI InChI=1S/C17H16FN5OS/c1-23-6-5-21-17(23)25-15-8-12(14(20)9-13(15)18)16(24)22-11-4-2-3-10(19)7-11/h2-9H,19-20H2,1H3,(H,22,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.68E+3n/an/an/an/a7.222



Shanghai Institutes for Biological Sciences



Assay Description
The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...


Bioorg Med Chem 17: 7301-12 (2009)


Article DOI: 10.1016/j.bmc.2009.08.045
BindingDB Entry DOI: 10.7270/Q2DF6PK0
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM34073
PNG
(benzamide derivative, 13a)
Show SMILES Nc1cccc(NC(=O)c2cc(Sc3nccs3)c(F)cc2N)c1
Show InChI InChI=1S/C16H13FN4OS2/c17-12-8-13(19)11(7-14(12)24-16-20-4-5-23-16)15(22)21-10-3-1-2-9(18)6-10/h1-8H,18-19H2,(H,21,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 5.40E+3n/an/an/an/a7.222



Shanghai Institutes for Biological Sciences



Assay Description
The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...


Bioorg Med Chem 17: 7301-12 (2009)


Article DOI: 10.1016/j.bmc.2009.08.045
BindingDB Entry DOI: 10.7270/Q2DF6PK0
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM34074
PNG
(benzamide derivative, 13b)
Show SMILES Cc1csc(Sc2cc(C(=O)Nc3cccc(N)c3)c(N)cc2F)n1
Show InChI InChI=1S/C17H15FN4OS2/c1-9-8-24-17(21-9)25-15-6-12(14(20)7-13(15)18)16(23)22-11-4-2-3-10(19)5-11/h2-8H,19-20H2,1H3,(H,22,23)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.50E+3n/an/an/an/a7.222



Shanghai Institutes for Biological Sciences



Assay Description
The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...


Bioorg Med Chem 17: 7301-12 (2009)


Article DOI: 10.1016/j.bmc.2009.08.045
BindingDB Entry DOI: 10.7270/Q2DF6PK0
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM34075
PNG
(benzamide derivative, 13c)
Show SMILES Nc1cccc(NC(=O)c2cc(Sc3nncs3)c(F)cc2N)c1
Show InChI InChI=1S/C15H12FN5OS2/c16-11-6-12(18)10(5-13(11)24-15-21-19-7-23-15)14(22)20-9-3-1-2-8(17)4-9/h1-7H,17-18H2,(H,20,22)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.77E+4n/an/an/an/a7.222



Shanghai Institutes for Biological Sciences



Assay Description
The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...


Bioorg Med Chem 17: 7301-12 (2009)


Article DOI: 10.1016/j.bmc.2009.08.045
BindingDB Entry DOI: 10.7270/Q2DF6PK0
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM34076
PNG
(benzamide derivative, 13d)
Show SMILES Nc1cccc(NC(=O)c2cc(Sc3ccccn3)c(F)cc2N)c1
Show InChI InChI=1S/C18H15FN4OS/c19-14-10-15(21)13(9-16(14)25-17-6-1-2-7-22-17)18(24)23-12-5-3-4-11(20)8-12/h1-10H,20-21H2,(H,23,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.06E+4n/an/an/an/a7.222



Shanghai Institutes for Biological Sciences



Assay Description
The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...


Bioorg Med Chem 17: 7301-12 (2009)


Article DOI: 10.1016/j.bmc.2009.08.045
BindingDB Entry DOI: 10.7270/Q2DF6PK0
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM34077
PNG
(benzamide derivative, 13e)
Show SMILES Cc1cc(C)nc(Sc2cc(C(=O)Nc3cccc(N)c3)c(N)cc2F)n1
Show InChI InChI=1S/C19H18FN5OS/c1-10-6-11(2)24-19(23-10)27-17-8-14(16(22)9-15(17)20)18(26)25-13-5-3-4-12(21)7-13/h3-9H,21-22H2,1-2H3,(H,25,26)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 9.80E+3n/an/an/an/a7.222



Shanghai Institutes for Biological Sciences



Assay Description
The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...


Bioorg Med Chem 17: 7301-12 (2009)


Article DOI: 10.1016/j.bmc.2009.08.045
BindingDB Entry DOI: 10.7270/Q2DF6PK0
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM34078
PNG
(benzamide derivative, 13f)
Show SMILES Cn1ccnc1Sc1cc(NC(=O)c2cccc(N)c2)c(N)cc1F
Show InChI InChI=1S/C17H16FN5OS/c1-23-6-5-21-17(23)25-15-9-14(13(20)8-12(15)18)22-16(24)10-3-2-4-11(19)7-10/h2-9H,19-20H2,1H3,(H,22,24)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.89E+4n/an/an/an/a7.222



Shanghai Institutes for Biological Sciences



Assay Description
The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...


Bioorg Med Chem 17: 7301-12 (2009)


Article DOI: 10.1016/j.bmc.2009.08.045
BindingDB Entry DOI: 10.7270/Q2DF6PK0
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM34079
PNG
(benzamide derivative, 13g)
Show SMILES Cn1ccnc1Sc1cc(C(=O)Nc2cccc(CN)c2)c(N)cc1F
Show InChI InChI=1S/C18H18FN5OS/c1-24-6-5-22-18(24)26-16-8-13(15(21)9-14(16)19)17(25)23-12-4-2-3-11(7-12)10-20/h2-9H,10,20-21H2,1H3,(H,23,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.53E+4n/an/an/an/a7.222



Shanghai Institutes for Biological Sciences



Assay Description
The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...


Bioorg Med Chem 17: 7301-12 (2009)


Article DOI: 10.1016/j.bmc.2009.08.045
BindingDB Entry DOI: 10.7270/Q2DF6PK0
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM34080
PNG
(benzamide derivative, 13h)
Show SMILES Cn1ccnc1Sc1cc(C(=O)Nc2cccc(c2)C(F)(F)F)c(N)cc1F
Show InChI InChI=1S/C18H14F4N4OS/c1-26-6-5-24-17(26)28-15-8-12(14(23)9-13(15)19)16(27)25-11-4-2-3-10(7-11)18(20,21)22/h2-9H,23H2,1H3,(H,25,27)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.95E+3n/an/an/an/a7.222



Shanghai Institutes for Biological Sciences



Assay Description
The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...


Bioorg Med Chem 17: 7301-12 (2009)


Article DOI: 10.1016/j.bmc.2009.08.045
BindingDB Entry DOI: 10.7270/Q2DF6PK0
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM34081
PNG
(benzamide derivative, 13i)
Show SMILES Nc1cc(F)c(Sc2nccs2)cc1C(=O)Nc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C17H11F4N3OS2/c18-12-8-13(22)11(7-14(12)27-16-23-4-5-26-16)15(25)24-10-3-1-2-9(6-10)17(19,20)21/h1-8H,22H2,(H,24,25)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 2.11E+4n/an/an/an/a7.222



Shanghai Institutes for Biological Sciences



Assay Description
The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...


Bioorg Med Chem 17: 7301-12 (2009)


Article DOI: 10.1016/j.bmc.2009.08.045
BindingDB Entry DOI: 10.7270/Q2DF6PK0
More data for this
Ligand-Target Pair
Glycogen Phosphorylase (PYGM)


(Oryctolagus cuniculus (rabbit))
BDBM34082
PNG
(benzamide derivative, 13j)
Show SMILES Cc1csc(Sc2cc(C(=O)Nc3cccc(c3)C(F)(F)F)c(N)cc2F)n1
Show InChI InChI=1S/C18H13F4N3OS2/c1-9-8-27-17(24-9)28-15-6-12(14(23)7-13(15)19)16(26)25-11-4-2-3-10(5-11)18(20,21)22/h2-8H,23H2,1H3,(H,25,26)
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
DrugBank
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.25E+4n/an/an/an/a7.222



Shanghai Institutes for Biological Sciences



Assay Description
The enzymatic inhibition of phosphorylase activity was monitored using microplate reader (Bio-Rad). In brief, GPa activity was measured in the direct...


Bioorg Med Chem 17: 7301-12 (2009)


Article DOI: 10.1016/j.bmc.2009.08.045
BindingDB Entry DOI: 10.7270/Q2DF6PK0
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 744 total )  |  Next  |  Last  >>
Jump to: