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Compile Data Set for Download or QSAR

Found 2781 hits Enz. Inhib. hit(s) with Target = 'Histone Deacetylase 6 (HDAC6)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Histone deacetylase


(Homo sapiens (human))
BDBM24622
PNG
(3-[(dimethylamino)methyl]-N-{2-[4-(hydroxycarbamoy...)
Show SMILES CN(C)Cc1c(oc2ccccc12)C(=O)NCCOc1ccc(cc1)C(=O)NO
Show InChI InChI=1S/C21H23N3O5/c1-24(2)13-17-16-5-3-4-6-18(16)29-19(17)21(26)22-11-12-28-15-9-7-14(8-10-15)20(25)23-27/h3-10,27H,11-13H2,1-2H3,(H,22,26)(H,23,25)
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Article
PubMed
17 -43.9n/an/an/an/an/a7.422



Celera Genomics



Assay Description
HDAC activity was measured using a continuous trypsin-coupled assay. For inhibitor characterization, measurements were done using 96-well assay plat...


Mol Cancer Ther 5: 1309-17 (2006)


Article DOI: 10.1158/1535-7163.MCT-05-0442
BindingDB Entry DOI: 10.7270/Q2DF6PJJ
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM19149
PNG
(CHEMBL98 | N-hydroxy-N'-phenyloctanediamide | SAHA...)
Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccccc1
Show InChI InChI=1S/C14H20N2O3/c17-13(15-12-8-4-3-5-9-12)10-6-1-2-7-11-14(18)16-19/h3-5,8-9,19H,1-2,6-7,10-11H2,(H,15,17)(H,16,18)
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PubMed
21 -43.4n/an/an/an/an/a7.422



University of Notre Dame



Assay Description
To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...


J Med Chem 51: 2898-906 (2008)


Article DOI: 10.1021/jm7015254
BindingDB Entry DOI: 10.7270/Q2NC5ZG2
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM22450
PNG
(N-hydroxy-N -(4-{(2R,4S,6R)-4-phenyl-6-[(pyridin-4...)
Show SMILES ONC(=O)CCCCCCC(=O)Nc1ccc(cc1)[C@H]1O[C@@H](CSc2ccncc2)C[C@H](O1)c1ccccc1
Show InChI InChI=1S/C30H35N3O5S/c34-28(10-6-1-2-7-11-29(35)33-36)32-24-14-12-23(13-15-24)30-37-25(21-39-26-16-18-31-19-17-26)20-27(38-30)22-8-4-3-5-9-22/h3-5,8-9,12-19,25,27,30,36H,1-2,6-7,10-11,20-21H2,(H,32,34)(H,33,35)/t25-,27+,30+/m1/s1
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28 -42.7n/an/an/an/an/a7.422



University of Notre Dame



Assay Description
To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...


J Med Chem 51: 2898-906 (2008)


Article DOI: 10.1021/jm7015254
BindingDB Entry DOI: 10.7270/Q2NC5ZG2
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM22449
PNG
(CHEMBL356769 | N-(4-{(2R,4R,6S)-4-{[(4,5-diphenyl-...)
Show SMILES OCc1ccc(cc1)[C@@H]1C[C@H](CSc2nc(c(o2)-c2ccccc2)-c2ccccc2)O[C@@H](O1)c1ccc(NC(=O)CCCCCCC(=O)NO)cc1
Show InChI InChI=1S/C41H43N3O7S/c45-26-28-17-19-29(20-18-28)35-25-34(27-52-41-43-38(30-11-5-3-6-12-30)39(51-41)31-13-7-4-8-14-31)49-40(50-35)32-21-23-33(24-22-32)42-36(46)15-9-1-2-10-16-37(47)44-48/h3-8,11-14,17-24,34-35,40,45,48H,1-2,9-10,15-16,25-27H2,(H,42,46)(H,44,47)/t34-,35+,40+/m1/s1
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142 -38.7n/an/an/an/an/a7.422



University of Notre Dame



Assay Description
To assess the effect of test compounds on histone deacetylase enzyme function in Vitro, a fluorometric assay was performed using HDAC, which incubate...


J Med Chem 51: 2898-906 (2008)


Article DOI: 10.1021/jm7015254
BindingDB Entry DOI: 10.7270/Q2NC5ZG2
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110087
PNG
(US8609678, 4-((4-fluorophenyl)(hydroxy)(pyridin-2-...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(cc1)C(O)(c1ccc(F)cc1)c1ccccn1
Show InChI InChI=1S/C26H28FN3O4/c27-22-15-13-21(14-16-22)26(33,23-7-4-6-17-28-23)20-11-9-19(10-12-20)25(32)29-18-5-2-1-3-8-24(31)30-34/h4,6-7,9-17,33-34H,1-3,5,8,18H2,(H,29,32)(H,30,31)
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n/an/a 80n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110088
PNG
(US8609678, 4-((4-fluorophenyl)(hydroxy)(pyridin-2-...)
Show SMILES CN(CCCCCCC(=O)NO)C(=O)c1ccc(cc1)C(O)(c1ccc(F)cc1)c1ccccn1
Show InChI InChI=1S/C27H30FN3O4/c1-31(19-7-3-2-4-9-25(32)30-35)26(33)20-10-12-21(13-11-20)27(34,24-8-5-6-18-29-24)22-14-16-23(28)17-15-22/h5-6,8,10-18,34-35H,2-4,7,9,19H2,1H3,(H,30,32)
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n/an/a 284n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110089
PNG
(US8609678, 4-((4-fluorophenyl)(methoxy)(pyridin-2-...)
Show SMILES COC(c1ccc(F)cc1)(c1ccc(cc1)C(=O)NCCCCCCC(=O)NO)c1ccccn1
Show InChI InChI=1S/C27H30FN3O4/c1-35-27(24-8-5-7-18-29-24,22-14-16-23(28)17-15-22)21-12-10-20(11-13-21)26(33)30-19-6-3-2-4-9-25(32)31-34/h5,7-8,10-18,34H,2-4,6,9,19H2,1H3,(H,30,33)(H,31,32)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110090
PNG
(US8609678, 4-((4-fluorophenyl)(methoxy)(pyridin-2-...)
Show SMILES COC(c1ccc(F)cc1)(c1ccc(cc1)C(=O)N(C)CCCCCCC(=O)NO)c1ccccn1
Show InChI InChI=1S/C28H32FN3O4/c1-32(20-8-4-3-5-10-26(33)31-35)27(34)21-11-13-22(14-12-21)28(36-2,25-9-6-7-19-30-25)23-15-17-24(29)18-16-23/h6-7,9,11-19,35H,3-5,8,10,20H2,1-2H3,(H,31,33)
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n/an/a 361n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110091
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-4-(hyd...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(cc1)C(O)(c1nccs1)c1nccs1
Show InChI InChI=1S/C21H24N4O4S2/c26-17(25-29)5-3-1-2-4-10-22-18(27)15-6-8-16(9-7-15)21(28,19-23-11-13-30-19)20-24-12-14-31-20/h6-9,11-14,28-29H,1-5,10H2,(H,22,27)(H,25,26)
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n/an/a 141n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110092
PNG
(US8609678, 3-(bis(4-fluorophenyl)(hydroxy)methyl)-...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1cccc(c1)C(O)(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C27H28F2N2O4/c28-23-13-9-20(10-14-23)27(34,21-11-15-24(29)16-12-21)22-7-5-6-19(18-22)26(33)30-17-4-2-1-3-8-25(32)31-35/h5-7,9-16,18,34-35H,1-4,8,17H2,(H,30,33)(H,31,32)
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n/an/a 63n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110093
PNG
(US8609678, 3-(bis(4-fluorophenyl)(hydroxy)methyl)-...)
Show SMILES CN(CCCCCCC(=O)NO)C(=O)c1cccc(c1)C(O)(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C28H30F2N2O4/c1-32(18-5-3-2-4-9-26(33)31-36)27(34)20-7-6-8-23(19-20)28(35,21-10-14-24(29)15-11-21)22-12-16-25(30)17-13-22/h6-8,10-17,19,35-36H,2-5,9,18H2,1H3,(H,31,33)
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n/an/a 349n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110094
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-4-(2,2...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(cc1)C(O)(c1ccc(F)cc1)C(F)(F)F
Show InChI InChI=1S/C22H24F4N2O4/c23-18-12-10-17(11-13-18)21(31,22(24,25)26)16-8-6-15(7-9-16)20(30)27-14-4-2-1-3-5-19(29)28-32/h6-13,31-32H,1-5,14H2,(H,27,30)(H,28,29)
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n/an/a 50n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110095
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-4-(2,2...)
Show SMILES COC(c1ccc(F)cc1)(c1ccc(cc1)C(=O)NCCCCCCC(=O)NO)C(F)(F)F
Show InChI InChI=1S/C23H26F4N2O4/c1-33-22(23(25,26)27,18-11-13-19(24)14-12-18)17-9-7-16(8-10-17)21(31)28-15-5-3-2-4-6-20(30)29-32/h7-14,32H,2-6,15H2,1H3,(H,28,31)(H,29,30)
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n/an/a 174n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110096
PNG
(US8609678, 4-(2-(4-fluorophenyl)tetrahydrofuran-2-...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(cc1)C1(CCCO1)c1ccc(F)cc1
Show InChI InChI=1S/C24H29FN2O4/c25-21-13-11-20(12-14-21)24(15-5-17-31-24)19-9-7-18(8-10-19)23(29)26-16-4-2-1-3-6-22(28)27-30/h7-14,30H,1-6,15-17H2,(H,26,29)(H,27,28)
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n/an/a 47n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110097
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-2-((2-...)
Show SMILES OCCN(c1ccccc1)c1ncc(cn1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C20H27N5O4/c26-13-12-25(17-8-4-3-5-9-17)20-22-14-16(15-23-20)19(28)21-11-7-2-1-6-10-18(27)24-29/h3-5,8-9,14-15,26,29H,1-2,6-7,10-13H2,(H,21,28)(H,24,27)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110098
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-3-(hyd...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1cccc(c1)C(O)(c1ccccn1)c1ccccn1
Show InChI InChI=1S/C25H28N4O4/c30-23(29-33)14-3-1-2-6-17-28-24(31)19-10-9-11-20(18-19)25(32,21-12-4-7-15-26-21)22-13-5-8-16-27-22/h4-5,7-13,15-16,18,32-33H,1-3,6,14,17H2,(H,28,31)(H,29,30)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110099
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-3-(met...)
Show SMILES COC(c1cccc(c1)C(=O)NCCCCCCC(=O)NO)(c1ccccn1)c1ccccn1
Show InChI InChI=1S/C26H30N4O4/c1-34-26(22-13-5-8-16-27-22,23-14-6-9-17-28-23)21-12-10-11-20(19-21)25(32)29-18-7-3-2-4-15-24(31)30-33/h5-6,8-14,16-17,19,33H,2-4,7,15,18H2,1H3,(H,29,32)(H,30,31)
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n/an/a 217n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110100
PNG
(US8609678, 4-(hydroxy(4-(7-(hydroxyamino)-7-oxohep...)
Show SMILES CN(C)C(=O)c1ccc(cc1)C(O)(c1ccccc1)c1ccc(cc1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C30H35N3O5/c1-33(2)29(36)23-15-19-26(20-16-23)30(37,24-10-6-5-7-11-24)25-17-13-22(14-18-25)28(35)31-21-9-4-3-8-12-27(34)32-38/h5-7,10-11,13-20,37-38H,3-4,8-9,12,21H2,1-2H3,(H,31,35)(H,32,34)
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n/an/a 86n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110101
PNG
(US8609678, 3-(hydroxy(4-(7-(hydroxyamino)-7-oxohep...)
Show SMILES CN(C)C(=O)c1cccc(c1)C(O)(c1ccccc1)c1ccc(cc1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C30H35N3O5/c1-33(2)29(36)23-11-10-14-26(21-23)30(37,24-12-6-5-7-13-24)25-18-16-22(17-19-25)28(35)31-20-9-4-3-8-15-27(34)32-38/h5-7,10-14,16-19,21,37-38H,3-4,8-9,15,20H2,1-2H3,(H,31,35)(H,32,34)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110102
PNG
(US8609678, 2-(bis(4-fluorophenyl)amino)-N-(7-(hydr...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1cnc(nc1)N(c1ccc(F)cc1)c1ccc(F)cc1
Show InChI InChI=1S/C24H25F2N5O3/c25-18-6-10-20(11-7-18)31(21-12-8-19(26)9-13-21)24-28-15-17(16-29-24)23(33)27-14-4-2-1-3-5-22(32)30-34/h6-13,15-16,34H,1-5,14H2,(H,27,33)(H,30,32)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110103
PNG
(US8609678, N-(7-amino-7-oxoheptyl)-2-(diphenylamin...)
Show SMILES NC(=O)CCCCCCNC(=O)c1cnc(nc1)N(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H27N5O2/c25-22(30)15-9-1-2-10-16-26-23(31)19-17-27-24(28-18-19)29(20-11-5-3-6-12-20)21-13-7-4-8-14-21/h3-8,11-14,17-18H,1-2,9-10,15-16H2,(H2,25,30)(H,26,31)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110104
PNG
(US8609678, 4-((4-(7-(hydroxyamino)-7-oxoheptylcarb...)
Show SMILES COC(c1ccccc1)(c1ccc(cc1)C(=O)NCCCCCCC(=O)NO)c1ccc(cc1)C(=O)N(C)C
Show InChI InChI=1S/C31H37N3O5/c1-34(2)30(37)24-16-20-27(21-17-24)31(39-3,25-11-7-6-8-12-25)26-18-14-23(15-19-26)29(36)32-22-10-5-4-9-13-28(35)33-38/h6-8,11-12,14-21,38H,4-5,9-10,13,22H2,1-3H3,(H,32,36)(H,33,35)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110105
PNG
(US8609678, 3-((4-(7-(hydroxyamino)-7-oxoheptylcarb...)
Show SMILES COC(c1ccccc1)(c1ccc(cc1)C(=O)NCCCCCCC(=O)NO)c1cccc(c1)C(=O)N(C)C
Show InChI InChI=1S/C31H37N3O5/c1-34(2)30(37)24-12-11-15-27(22-24)31(39-3,25-13-7-6-8-14-25)26-19-17-23(18-20-26)29(36)32-21-10-5-4-9-16-28(35)33-38/h6-8,11-15,17-20,22,38H,4-5,9-10,16,21H2,1-3H3,(H,32,36)(H,33,35)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110106
PNG
(US8609678, 7-(2-(diphenylamino)pyrimidine-5-carbox...)
Show SMILES OC(=O)CCCCCCNC(=O)c1cnc(nc1)N(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C24H26N4O3/c29-22(30)15-9-1-2-10-16-25-23(31)19-17-26-24(27-18-19)28(20-11-5-3-6-12-20)21-13-7-4-8-14-21/h3-8,11-14,17-18H,1-2,9-10,15-16H2,(H,25,31)(H,29,30)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110107
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-4-(3-o...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1ccc(cc1)C1(OC(=O)c2ccccc12)c1ccccc1
Show InChI InChI=1S/C28H28N2O5/c31-25(30-34)14-6-1-2-9-19-29-26(32)20-15-17-22(18-16-20)28(21-10-4-3-5-11-21)24-13-8-7-12-23(24)27(33)35-28/h3-5,7-8,10-13,15-18,34H,1-2,6,9,14,19H2,(H,29,32)(H,30,31)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110108
PNG
(US8609678, 2-(bis(4-fluorophenyl)methylamino)-N-(7...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1cnc(NC(c2ccc(F)cc2)c2ccc(F)cc2)nc1
Show InChI InChI=1S/C25H27F2N5O3/c26-20-10-6-17(7-11-20)23(18-8-12-21(27)13-9-18)31-25-29-15-19(16-30-25)24(34)28-14-4-2-1-3-5-22(33)32-35/h6-13,15-16,23,35H,1-5,14H2,(H,28,34)(H,32,33)(H,29,30,31)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110109
PNG
(US8609678, 2-(3,4-dihydroquinolin-1(2H)-yl)-N-(7-(...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1cnc(nc1)N1CCCc2ccccc12
Show InChI InChI=1S/C21H27N5O3/c27-19(25-29)11-3-1-2-6-12-22-20(28)17-14-23-21(24-15-17)26-13-7-9-16-8-4-5-10-18(16)26/h4-5,8,10,14-15,29H,1-3,6-7,9,11-13H2,(H,22,28)(H,25,27)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110062
PNG
(US8609678, 4-(bis(3-fluorophenyl)(methoxy)methyl)-...)
Show SMILES COC(c1ccc(cc1)C(=O)N(C)CCCCCCC(=O)NO)(c1cccc(F)c1)c1cccc(F)c1
Show InChI InChI=1S/C29H32F2N2O4/c1-33(18-6-4-3-5-13-27(34)32-36)28(35)21-14-16-22(17-15-21)29(37-2,23-9-7-11-25(30)19-23)24-10-8-12-26(31)20-24/h7-12,14-17,19-20,36H,3-6,13,18H2,1-2H3,(H,32,34)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110110
PNG
(US8609678, 2-(3,4-dihydroisoquinolin-2(1H)-yl)-N-(...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1cnc(nc1)N1CCc2ccccc2C1
Show InChI InChI=1S/C21H27N5O3/c27-19(25-29)9-3-1-2-6-11-22-20(28)18-13-23-21(24-14-18)26-12-10-16-7-4-5-8-17(16)15-26/h4-5,7-8,13-14,29H,1-3,6,9-12,15H2,(H,22,28)(H,25,27)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110111
PNG
(US8609678, 2-((2,2-bis(4-fluorophenyl)ethyl)(2-hyd...)
Show SMILES OCCN(CC(c1ccc(F)cc1)c1ccc(F)cc1)c1ncc(cn1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C28H33F2N5O4/c29-23-10-6-20(7-11-23)25(21-8-12-24(30)13-9-21)19-35(15-16-36)28-32-17-22(18-33-28)27(38)31-14-4-2-1-3-5-26(37)34-39/h6-13,17-18,25,36,39H,1-5,14-16,19H2,(H,31,38)(H,34,37)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110112
PNG
(US8609678, 2-((2-(1H-indol-3-yl)ethyl)(2-hydroxyet...)
Show SMILES OCCN(CCc1c[nH]c2ccccc12)c1ncc(cn1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C24H32N6O4/c31-14-13-30(12-10-18-15-26-21-8-5-4-7-20(18)21)24-27-16-19(17-28-24)23(33)25-11-6-2-1-3-9-22(32)29-34/h4-5,7-8,15-17,26,31,34H,1-3,6,9-14H2,(H,25,33)(H,29,32)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110113
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-2-morp...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1cnc(nc1)N1CCOCC1
Show InChI InChI=1S/C16H25N5O4/c22-14(20-24)5-3-1-2-4-6-17-15(23)13-11-18-16(19-12-13)21-7-9-25-10-8-21/h11-12,24H,1-10H2,(H,17,23)(H,20,22)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110114
PNG
(US8609678, 2-((2S,6R)-2,6-dimethylmorpholino)-N-(7...)
Show SMILES C[C@H]1CN(C[C@@H](C)O1)c1ncc(cn1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C18H29N5O4/c1-13-11-23(12-14(2)27-13)18-20-9-15(10-21-18)17(25)19-8-6-4-3-5-7-16(24)22-26/h9-10,13-14,26H,3-8,11-12H2,1-2H3,(H,19,25)(H,22,24)/t13-,14+
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110115
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-2-(pip...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1cnc(nc1)N1CCNCC1
Show InChI InChI=1S/C16H26N6O3/c23-14(21-25)5-3-1-2-4-6-18-15(24)13-11-19-16(20-12-13)22-9-7-17-8-10-22/h11-12,17,25H,1-10H2,(H,18,24)(H,21,23)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110116
PNG
(US8609678, 2-(4-benzylpiperazin-1-yl)-N-(7-(hydrox...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1cnc(nc1)N1CCN(Cc2ccccc2)CC1
Show InChI InChI=1S/C23H32N6O3/c30-21(27-32)10-6-1-2-7-11-24-22(31)20-16-25-23(26-17-20)29-14-12-28(13-15-29)18-19-8-4-3-5-9-19/h3-5,8-9,16-17,32H,1-2,6-7,10-15,18H2,(H,24,31)(H,27,30)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110117
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-2-(4-(...)
Show SMILES OCCN1CCN(CC1)c1ncc(cn1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C18H30N6O4/c25-12-11-23-7-9-24(10-8-23)18-20-13-15(14-21-18)17(27)19-6-4-2-1-3-5-16(26)22-28/h13-14,25,28H,1-12H2,(H,19,27)(H,22,26)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110118
PNG
(US8609678, 2-(6,7-dimethoxy-3,4-dihydroisoquinolin...)
Show SMILES COc1cc2CCN(Cc2cc1OC)c1ncc(cn1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C23H31N5O5/c1-32-19-11-16-8-10-28(15-17(16)12-20(19)33-2)23-25-13-18(14-26-23)22(30)24-9-6-4-3-5-7-21(29)27-31/h11-14,31H,3-10,15H2,1-2H3,(H,24,30)(H,27,29)
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Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110119
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-2-(3-(...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1cnc(nc1)N1CCn2c(C1)nnc2C(F)(F)F
Show InChI InChI=1S/C18H23F3N8O3/c19-18(20,21)16-26-25-13-11-28(7-8-29(13)16)17-23-9-12(10-24-17)15(31)22-6-4-2-1-3-5-14(30)27-32/h9-10,32H,1-8,11H2,(H,22,31)(H,27,30)
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n/an/a 149n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110120
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-2-(4-p...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1cnc(nc1)N1CCN(CC1)c1ccccc1
Show InChI InChI=1S/C22H30N6O3/c29-20(26-31)10-6-1-2-7-11-23-21(30)18-16-24-22(25-17-18)28-14-12-27(13-15-28)19-8-4-3-5-9-19/h3-5,8-9,16-17,31H,1-2,6-7,10-15H2,(H,23,30)(H,26,29)
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n/an/a 57n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110121
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-2-(4-(...)
Show SMILES COc1ccc(cc1)N1CCN(CC1)c1ncc(cn1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C23H32N6O4/c1-33-20-9-7-19(8-10-20)28-12-14-29(15-13-28)23-25-16-18(17-26-23)22(31)24-11-5-3-2-4-6-21(30)27-32/h7-10,16-17,32H,2-6,11-15H2,1H3,(H,24,31)(H,27,30)
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n/an/a 58n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110122
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-2-(4-(...)
Show SMILES COCCN1CCN(CC1)c1ncc(cn1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C19H32N6O4/c1-29-13-12-24-8-10-25(11-9-24)19-21-14-16(15-22-19)18(27)20-7-5-3-2-4-6-17(26)23-28/h14-15,28H,2-13H2,1H3,(H,20,27)(H,23,26)
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n/an/a 133n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110123
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-2-(4-(...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1cnc(nc1)N1CCN(CC1)c1nccc(n1)C(F)(F)F
Show InChI InChI=1S/C21H27F3N8O3/c22-21(23,24)16-6-8-26-20(29-16)32-11-9-31(10-12-32)19-27-13-15(14-28-19)18(34)25-7-4-2-1-3-5-17(33)30-35/h6,8,13-14,35H,1-5,7,9-12H2,(H,25,34)(H,30,33)
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n/an/a 54n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110124
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-2-(2-(...)
Show SMILES OCC1CN(CCO1)c1ncc(cn1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C17H27N5O5/c23-12-14-11-22(7-8-27-14)17-19-9-13(10-20-17)16(25)18-6-4-2-1-3-5-15(24)21-26/h9-10,14,23,26H,1-8,11-12H2,(H,18,25)(H,21,24)
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n/an/a 34n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110125
PNG
(US8609678, (R)-N-(7-(hydroxyamino)-7-oxoheptyl)-2-...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1cnc(nc1)N1CCC[C@@H](O)C1
Show InChI InChI=1S/C17H27N5O4/c23-14-6-5-9-22(12-14)17-19-10-13(11-20-17)16(25)18-8-4-2-1-3-7-15(24)21-26/h10-11,14,23,26H,1-9,12H2,(H,18,25)(H,21,24)/t14-/m1/s1
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n/an/a 49n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110126
PNG
(US8609678, 2-(4-carbamoylpiperidin-1-yl)-N-(7-(hyd...)
Show SMILES NC(=O)C1CCN(CC1)c1ncc(cn1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C18H28N6O4/c19-16(26)13-6-9-24(10-7-13)18-21-11-14(12-22-18)17(27)20-8-4-2-1-3-5-15(25)23-28/h11-13,28H,1-10H2,(H2,19,26)(H,20,27)(H,23,25)
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n/an/a 41n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110127
PNG
(US8609678, 2-(4-hydroxy-4-phenylpiperidin-1-yl)-N-...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1cnc(nc1)N1CCC(O)(CC1)c1ccccc1
Show InChI InChI=1S/C23H31N5O4/c29-20(27-32)10-6-1-2-7-13-24-21(30)18-16-25-22(26-17-18)28-14-11-23(31,12-15-28)19-8-4-3-5-9-19/h3-5,8-9,16-17,31-32H,1-2,6-7,10-15H2,(H,24,30)(H,27,29)
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n/an/a 39n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110128
PNG
(US8609678, 2-(4-(4-chlorophenyl)-4-hydroxypiperidi...)
Show SMILES ONC(=O)CCCCCCNC(=O)c1cnc(nc1)N1CCC(O)(CC1)c1ccc(Cl)cc1
Show InChI InChI=1S/C23H30ClN5O4/c24-19-8-6-18(7-9-19)23(32)10-13-29(14-11-23)22-26-15-17(16-27-22)21(31)25-12-4-2-1-3-5-20(30)28-33/h6-9,15-16,32-33H,1-5,10-14H2,(H,25,31)(H,28,30)
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n/an/a 53n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110129
PNG
(US8609678, (R)-2-(3-(dimethylamino)pyrrolidin-1-yl...)
Show SMILES CN(C)[C@@H]1CCN(C1)c1ncc(cn1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C18H30N6O3/c1-23(2)15-8-10-24(13-15)18-20-11-14(12-21-18)17(26)19-9-6-4-3-5-7-16(25)22-27/h11-12,15,27H,3-10,13H2,1-2H3,(H,19,26)(H,22,25)/t15-/m1/s1
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n/an/a 80n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110130
PNG
(US8609678, (S)-N-(7-(hydroxyamino)-7-oxoheptyl)-2-...)
Show SMILES OC[C@@H]1CCCN1c1ncc(cn1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C17H27N5O4/c23-12-14-6-5-9-22(14)17-19-10-13(11-20-17)16(25)18-8-4-2-1-3-7-15(24)21-26/h10-11,14,23,26H,1-9,12H2,(H,18,25)(H,21,24)/t14-/m0/s1
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n/an/a 30n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
Histone deacetylase


(Homo sapiens (human))
BDBM110131
PNG
(US8609678, N-(7-(hydroxyamino)-7-oxoheptyl)-2-(4-m...)
Show SMILES CN1CCN(C(C1)c1ccccc1)c1ncc(cn1)C(=O)NCCCCCCC(=O)NO
Show InChI InChI=1S/C23H32N6O3/c1-28-13-14-29(20(17-28)18-9-5-4-6-10-18)23-25-15-19(16-26-23)22(31)24-12-8-3-2-7-11-21(30)27-32/h4-6,9-10,15-16,20,32H,2-3,7-8,11-14,17H2,1H3,(H,24,31)(H,27,30)
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n/an/a 51n/an/an/an/a7.4n/a



Acetylon Pharmaceuticals

US Patent


Assay Description
Compounds for testing were diluted in DMSO to 50 fold the final concentration and a ten point three fold dilution series was made. The compounds were...


US Patent US8609678 (2013)


BindingDB Entry DOI: 10.7270/Q25M64BS
More data for this
Ligand-Target Pair
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