BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 412 hits Enz. Inhib. hit(s) with Target = 'IgG receptor FcRn large subunit p51'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50314079
PNG
((5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-23-[...)
Show SMILES CC(C)C[C@@H]1N(C)C(=O)CN2CCC[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)CNC(=O)[C@H](C)N(C)C(=O)[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]3CCCN3C(=O)C(=O)[C@H](Cc3ccc(O)cc3)NC1=O)C(N)=O)C2=O
Show InChI InChI=1S/C75H103N19O16S2/c1-42(2)32-58-70(107)86-52(33-47-25-27-49(96)28-26-47)61(99)72(109)94-31-17-24-57(94)69(106)89-56(63(76)100)40-111-112-75(5,6)62(90-68(105)54(35-46-20-13-10-14-21-46)87-65(102)50(83-44(4)95)22-15-29-80-74(77)78)73(110)91(7)43(3)64(101)81-38-59(97)84-55(36-48-37-79-41-82-48)67(104)88-53(34-45-18-11-9-12-19-45)66(103)85-51-23-16-30-93(71(51)108)39-60(98)92(58)8/h9-14,18-21,25-28,37,41-43,50-58,62,96H,15-17,22-24,29-36,38-40H2,1-8H3,(H2,76,100)(H,79,82)(H,81,101)(H,83,95)(H,84,97)(H,85,103)(H,86,107)(H,87,102)(H,88,104)(H,89,106)(H,90,105)(H4,77,78,80)/t43-,50-,51-,52-,53-,54-,55-,56-,57-,58-,62+/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 150n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assay


J Med Chem 53: 1587-96 (2010)


Article DOI: 10.1021/jm901128z
BindingDB Entry DOI: 10.7270/Q23R0T1H
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50314080
PNG
((3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-...)
Show SMILES CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O
Show InChI InChI=1S/C73H101N19O17S2/c1-40(2)29-55-68(106)84-49(30-45-23-25-47(95)26-24-45)60(99)71(109)92-28-16-22-54(92)67(105)87-53(62(74)100)38-110-111-73(5,6)61(89-66(104)51(32-44-19-13-10-14-20-44)86-64(102)48(82-42(4)94)21-15-27-78-72(75)76)70(108)88-59(41(3)93)69(107)79-35-56(96)83-52(33-46-34-77-39-81-46)65(103)85-50(31-43-17-11-9-12-18-43)63(101)80-36-57(97)90(7)37-58(98)91(55)8/h9-14,17-20,23-26,34,39-41,48-55,59,61,93,95H,15-16,21-22,27-33,35-38H2,1-8H3,(H2,74,100)(H,77,81)(H,79,107)(H,80,101)(H,82,94)(H,83,96)(H,84,106)(H,85,103)(H,86,102)(H,87,105)(H,88,108)(H,89,104)(H4,75,76,78)/t41-,48+,49+,50+,51+,52+,53+,54+,55+,59+,61-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 31n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assay


J Med Chem 53: 1587-96 (2010)


Article DOI: 10.1021/jm901128z
BindingDB Entry DOI: 10.7270/Q23R0T1H
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50314081
PNG
((3R,8R,11S,17S,26S,29S,35aS)-8-((S)-2-((S)-2-aceta...)
Show SMILES CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccc(cc2)N=C(N)N)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)[C@@H](C)O
Show InChI InChI=1S/C68H97N19O16S2/c1-36(2)28-50-62(100)80-45(29-41-20-24-43(90)25-21-41)55(94)65(103)87-27-13-17-49(87)61(99)82-48(57(69)95)35-104-105-68(5,6)56(84-60(98)47(30-39-14-10-9-11-15-39)81-59(97)44(77-38(4)89)16-12-26-74-66(70)71)64(102)83-54(37(3)88)63(101)75-32-51(91)79-46(31-40-18-22-42(23-19-40)78-67(72)73)58(96)76-33-52(92)85(7)34-53(93)86(50)8/h9-11,14-15,18-25,36-37,44-50,54,56,88,90H,12-13,16-17,26-35H2,1-8H3,(H2,69,95)(H,75,101)(H,76,96)(H,77,89)(H,79,91)(H,80,100)(H,81,97)(H,82,99)(H,83,102)(H,84,98)(H4,70,71,74)(H4,72,73,78)/t37-,44+,45+,46+,47+,48+,49+,50+,54+,56-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 62n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assay


J Med Chem 53: 1587-96 (2010)


Article DOI: 10.1021/jm901128z
BindingDB Entry DOI: 10.7270/Q23R0T1H
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50314082
PNG
((S)-N1-((S)-1-((S)-1-((3S,11S,14S,20S,23S,32S,35S,...)
Show SMILES CC(C)C[C@@H]1N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CC(=O)NCCCC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(C)=O)[C@@H](C)O
Show InChI InChI=1S/C91H128N26O24/c1-49(2)36-68-88(139)108-60(37-54-26-28-56(120)29-27-54)77(128)90(141)117-35-17-25-67(117)87(138)107-57(81(132)111-64(41-70(93)122)80(131)102-46-74(126)116-34-16-24-66(116)78(94)129)22-13-14-32-98-71(123)42-65(112-84(135)62(39-53-20-11-8-12-21-53)110-82(133)58(23-15-33-99-91(95)96)106-83(134)59(104-51(4)119)30-31-69(92)121)86(137)113-76(50(3)118)89(140)100-44-72(124)105-63(40-55-43-97-48-103-55)85(136)109-61(38-52-18-9-7-10-19-52)79(130)101-45-73(125)114(5)47-75(127)115(68)6/h7-12,18-21,26-29,43,48-50,57-68,76,118,120H,13-17,22-25,30-42,44-47H2,1-6H3,(H2,92,121)(H2,93,122)(H2,94,129)(H,97,103)(H,98,123)(H,100,140)(H,101,130)(H,102,131)(H,104,119)(H,105,124)(H,106,134)(H,107,138)(H,108,139)(H,109,136)(H,110,133)(H,111,132)(H,112,135)(H,113,137)(H4,95,96,99)/t50-,57+,58+,59+,60+,61+,62+,63+,64+,65+,66+,67+,68+,76+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 2.60E+3n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assay


J Med Chem 53: 1587-96 (2010)


Article DOI: 10.1021/jm901128z
BindingDB Entry DOI: 10.7270/Q23R0T1H
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50314106
PNG
((S)-N1-((S)-1-((S)-1-((3R,8R,11S,17S,20S,29S,32S,3...)
Show SMILES CC(C)C[C@@H]1NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(=O)[C@H](CCC(N)=O)NC(C)=O)[C@@H](C)O
Show InChI InChI=1S/C85H117N25O23S2/c1-44(2)30-55-77(126)102-54(31-49-21-23-51(113)24-22-49)71(120)84(133)110-29-13-20-63(110)82(131)107-60(80(129)105-59(35-65(87)115)74(123)96-40-69(119)109-28-12-19-62(109)72(88)121)41-134-135-42-61(106-78(127)57(33-48-16-9-6-10-17-48)104-75(124)52(18-11-27-92-85(89)90)101-76(125)53(98-46(4)112)25-26-64(86)114)81(130)108-70(45(3)111)83(132)95-39-68(118)100-58(34-50-36-91-43-97-50)79(128)103-56(32-47-14-7-5-8-15-47)73(122)94-37-66(116)93-38-67(117)99-55/h5-10,14-17,21-24,36,43-45,52-63,70,111,113H,11-13,18-20,25-35,37-42H2,1-4H3,(H2,86,114)(H2,87,115)(H2,88,121)(H,91,97)(H,93,116)(H,94,122)(H,95,132)(H,96,123)(H,98,112)(H,99,117)(H,100,118)(H,101,125)(H,102,126)(H,103,128)(H,104,124)(H,105,129)(H,106,127)(H,107,131)(H,108,130)(H4,89,90,92)/t45-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,70+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 5.30E+3n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assay


J Med Chem 53: 1587-96 (2010)


Article DOI: 10.1021/jm901128z
BindingDB Entry DOI: 10.7270/Q23R0T1H
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50314107
PNG
((3R,8R,11S,17S,20S,29S,32S,38aS)-17-((1H-imidazol-...)
Show SMILES CC(C)C[C@@H]1NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(N)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)[C@@H](C)O
Show InChI InChI=1S/C69H93N19O17S2/c1-37(2)25-47-62(99)82-46(26-42-19-21-44(91)22-20-42)58(95)68(105)88-24-12-18-53(88)66(103)85-51(59(70)96)34-106-107-35-52(86-63(100)49(28-41-15-9-6-10-16-41)84-61(98)45(79-39(4)90)17-11-23-74-69(71)72)65(102)87-57(38(3)89)67(104)77-33-56(94)81-50(29-43-30-73-36-78-43)64(101)83-48(27-40-13-7-5-8-14-40)60(97)76-31-54(92)75-32-55(93)80-47/h5-10,13-16,19-22,30,36-38,45-53,57,89,91H,11-12,17-18,23-29,31-35H2,1-4H3,(H2,70,96)(H,73,78)(H,75,92)(H,76,97)(H,77,104)(H,79,90)(H,80,93)(H,81,94)(H,82,99)(H,83,101)(H,84,98)(H,85,103)(H,86,100)(H,87,102)(H4,71,72,74)/t38-,45+,46+,47+,48+,49+,50+,51+,52+,53+,57+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 5.90E+3n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assay


J Med Chem 53: 1587-96 (2010)


Article DOI: 10.1021/jm901128z
BindingDB Entry DOI: 10.7270/Q23R0T1H
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270965
PNG
((2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3R)-3-[(2S)-2...)
Show SMILES CC(C)C[C@H](N(C)C(=O)CN1CCC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C72H102N18O16S2/c1-40(2)30-55(65(100)84-52(33-44-23-25-46(92)26-24-44)69(104)90-29-15-22-54(90)64(99)85-53(38-107)70(105)106)88(6)57(94)37-89-28-14-21-48(68(89)103)81-61(96)49(31-42-16-9-7-10-17-42)83-62(97)51(34-45-35-76-39-79-45)80-56(93)36-78-66(101)58(41(3)91)86-67(102)59(72(4,5)108)87-63(98)50(32-43-18-11-8-12-19-43)82-60(95)47(73)20-13-27-77-71(74)75/h7-12,16-19,23-26,35,39-41,47-55,58-59,91-92,107-108H,13-15,20-22,27-34,36-38,73H2,1-6H3,(H,76,79)(H,78,101)(H,80,93)(H,81,96)(H,82,95)(H,83,97)(H,84,100)(H,85,99)(H,86,102)(H,87,98)(H,105,106)(H4,74,75,77)/t41-,47+,48-,49+,50+,51+,52+,53+,54+,55+,58+,59+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 43n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270964
PNG
((2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{[(3S,6R,8aR)-6-[(...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H]1CS[C@@H]2CC[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N12)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C72H100N18O16S3/c1-38(2)28-47(60(95)85-51(31-42-20-22-44(92)23-21-42)68(103)89-27-13-19-53(89)64(99)86-52(35-107)70(105)106)84-65(100)54-36-109-56-25-24-46(69(104)90(54)56)81-61(96)48(29-40-14-8-6-9-15-40)83-62(97)50(32-43-33-76-37-79-43)80-55(93)34-78-66(101)57(39(3)91)87-67(102)58(72(4,5)108)88-63(98)49(30-41-16-10-7-11-17-41)82-59(94)45(73)18-12-26-77-71(74)75/h6-11,14-17,20-23,33,37-39,45-54,56-58,91-92,107-108H,12-13,18-19,24-32,34-36,73H2,1-5H3,(H,76,79)(H,78,101)(H,80,93)(H,81,96)(H,82,94)(H,83,97)(H,84,100)(H,85,95)(H,86,99)(H,87,102)(H,88,98)(H,105,106)(H4,74,75,77)/t39-,45+,46-,47+,48+,49+,50+,51+,52+,53+,54-,56-,57+,58+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 320n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270962
PNG
((2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{[(3S,6R)-6-[(2S)-...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H]1CSC2C[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N12)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C71H98N18O16S3/c1-37(2)26-45(59(94)83-49(29-41-20-22-43(91)23-21-41)67(102)88-25-13-19-52(88)63(98)85-51(34-106)69(104)105)82-64(99)53-35-108-55-31-50(68(103)89(53)55)84-60(95)46(27-39-14-8-6-9-15-39)81-61(96)48(30-42-32-75-36-78-42)79-54(92)33-77-65(100)56(38(3)90)86-66(101)57(71(4,5)107)87-62(97)47(28-40-16-10-7-11-17-40)80-58(93)44(72)18-12-24-76-70(73)74/h6-11,14-17,20-23,32,36-38,44-53,55-57,90-91,106-107H,12-13,18-19,24-31,33-35,72H2,1-5H3,(H,75,78)(H,77,100)(H,79,92)(H,80,93)(H,81,96)(H,82,99)(H,83,94)(H,84,95)(H,85,98)(H,86,101)(H,87,97)(H,104,105)(H4,73,74,76)/t38-,44+,45+,46+,47+,48+,49+,50-,51+,52+,53-,55?,56+,57+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 990n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270961
PNG
((2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3R)-3-[(2S)-2...)
Show SMILES CC(C)C[C@H](NC(=O)CN1CCCC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C72H102N18O16S2/c1-40(2)30-49(61(96)85-53(33-44-23-25-46(92)26-24-44)69(104)90-29-15-22-55(90)65(100)86-54(38-107)70(105)106)81-57(94)37-89-28-13-12-21-48(68(89)103)82-62(97)50(31-42-16-8-6-9-17-42)84-63(98)52(34-45-35-76-39-79-45)80-56(93)36-78-66(101)58(41(3)91)87-67(102)59(72(4,5)108)88-64(99)51(32-43-18-10-7-11-19-43)83-60(95)47(73)20-14-27-77-71(74)75/h6-11,16-19,23-26,35,39-41,47-55,58-59,91-92,107-108H,12-15,20-22,27-34,36-38,73H2,1-5H3,(H,76,79)(H,78,101)(H,80,93)(H,81,94)(H,82,97)(H,83,95)(H,84,98)(H,85,96)(H,86,100)(H,87,102)(H,88,99)(H,105,106)(H4,74,75,77)/t41-,47+,48-,49+,50+,51+,52+,53+,54+,55+,58+,59+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 103n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270960
PNG
((2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3S)-3-[(2S)-2...)
Show SMILES CC(C)C[C@H](NC(=O)CN1CCC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C71H100N18O16S2/c1-39(2)29-48(60(95)84-52(32-43-22-24-45(91)25-23-43)68(103)89-28-14-21-54(89)64(99)85-53(37-106)69(104)105)80-56(93)36-88-27-13-20-47(67(88)102)81-61(96)49(30-41-15-8-6-9-16-41)83-62(97)51(33-44-34-75-38-78-44)79-55(92)35-77-65(100)57(40(3)90)86-66(101)58(71(4,5)107)87-63(98)50(31-42-17-10-7-11-18-42)82-59(94)46(72)19-12-26-76-70(73)74/h6-11,15-18,22-25,34,38-40,46-54,57-58,90-91,106-107H,12-14,19-21,26-33,35-37,72H2,1-5H3,(H,75,78)(H,77,100)(H,79,92)(H,80,93)(H,81,96)(H,82,94)(H,83,97)(H,84,95)(H,85,99)(H,86,101)(H,87,98)(H,104,105)(H4,73,74,76)/t40-,46+,47+,48+,49+,50+,51+,52+,53+,54+,57+,58+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 670n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270959
PNG
((2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3R)-3-[(2S)-2...)
Show SMILES CC(C)C[C@H](NC(=O)CN1CCC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C71H100N18O16S2/c1-39(2)29-48(60(95)84-52(32-43-22-24-45(91)25-23-43)68(103)89-28-14-21-54(89)64(99)85-53(37-106)69(104)105)80-56(93)36-88-27-13-20-47(67(88)102)81-61(96)49(30-41-15-8-6-9-16-41)83-62(97)51(33-44-34-75-38-78-44)79-55(92)35-77-65(100)57(40(3)90)86-66(101)58(71(4,5)107)87-63(98)50(31-42-17-10-7-11-18-42)82-59(94)46(72)19-12-26-76-70(73)74/h6-11,15-18,22-25,34,38-40,46-54,57-58,90-91,106-107H,12-14,19-21,26-33,35-37,72H2,1-5H3,(H,75,78)(H,77,100)(H,79,92)(H,80,93)(H,81,96)(H,82,94)(H,83,97)(H,84,95)(H,85,99)(H,86,101)(H,87,98)(H,104,105)(H4,73,74,76)/t40-,46+,47-,48+,49+,50+,51+,52+,53+,54+,57+,58-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 160n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270958
PNG
((2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-{2-[(3R)-3-[(2S)-2...)
Show SMILES CC(C)C[C@H](NC(=O)CN1CC[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C1=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C70H98N18O16S2/c1-38(2)28-47(59(94)83-51(31-42-20-22-44(90)23-21-42)67(102)88-26-13-19-53(88)63(98)84-52(36-105)68(103)104)79-55(92)35-87-27-24-46(66(87)101)80-60(95)48(29-40-14-8-6-9-15-40)82-61(96)50(32-43-33-74-37-77-43)78-54(91)34-76-64(99)56(39(3)89)85-65(100)57(70(4,5)106)86-62(97)49(30-41-16-10-7-11-17-41)81-58(93)45(71)18-12-25-75-69(72)73/h6-11,14-17,20-23,33,37-39,45-53,56-57,89-90,105-106H,12-13,18-19,24-32,34-36,71H2,1-5H3,(H,74,77)(H,76,99)(H,78,91)(H,79,92)(H,80,95)(H,81,93)(H,82,96)(H,83,94)(H,84,98)(H,85,100)(H,86,97)(H,103,104)(H4,72,73,75)/t39-,45+,46-,47+,48+,49+,50+,51+,52+,53+,56+,57-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 280n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270987
PNG
(CHEMBL443697 | SYN-1327)
Show SMILES CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C70H100N18O16S2/c1-39(2)28-53(64(99)82-50(31-43-22-24-45(90)25-23-43)67(102)88-27-15-21-52(88)63(98)83-51(37-105)68(103)104)87(7)56(93)36-86(6)55(92)35-77-60(95)47(29-41-16-10-8-11-17-41)81-61(96)49(32-44-33-74-38-78-44)79-54(91)34-76-65(100)57(40(3)89)84-66(101)58(70(4,5)106)85-62(97)48(30-42-18-12-9-13-19-42)80-59(94)46(71)20-14-26-75-69(72)73/h8-13,16-19,22-25,33,38-40,46-53,57-58,89-90,105-106H,14-15,20-21,26-32,34-37,71H2,1-7H3,(H,74,78)(H,76,100)(H,77,95)(H,79,91)(H,80,94)(H,81,96)(H,82,99)(H,83,98)(H,84,101)(H,85,97)(H,103,104)(H4,72,73,75)/t40-,46+,47+,48+,49+,50+,51+,52+,53+,57+,58-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 31n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270892
PNG
((2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2...)
Show SMILES CC(C)C[C@H](N(C)C(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C86H124N24O22S2/c1-45(2)33-63(80(127)104-59(36-50-24-26-52(112)27-25-50)83(130)110-32-15-22-61(110)79(126)105-60(43-133)78(125)103-58(38-65(89)114)73(120)96-42-68(117)109-31-16-23-62(109)84(131)132)108(7)67(116)41-95-71(118)46(3)98-75(122)55(34-48-17-10-8-11-18-48)102-76(123)57(37-51-39-92-44-97-51)99-66(115)40-94-81(128)69(47(4)111)106-82(129)70(86(5,6)134)107-77(124)56(35-49-19-12-9-13-20-49)101-74(121)54(21-14-30-93-85(90)91)100-72(119)53(87)28-29-64(88)113/h8-13,17-20,24-27,39,44-47,53-63,69-70,111-112,133-134H,14-16,21-23,28-38,40-43,87H2,1-7H3,(H2,88,113)(H2,89,114)(H,92,97)(H,94,128)(H,95,118)(H,96,120)(H,98,122)(H,99,115)(H,100,119)(H,101,121)(H,102,123)(H,103,125)(H,104,127)(H,105,126)(H,106,129)(H,107,124)(H,131,132)(H4,90,91,93)/t46-,47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,69+,70-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 230n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270891
PNG
((2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2...)
Show SMILES CC(C)C[C@H](N(C)C(=O)CNC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C92H128N24O22S2/c1-50(2)37-69(86(133)110-65(41-55-28-30-57(118)31-29-55)89(136)116-36-17-26-67(116)85(132)111-66(48-139)84(131)109-64(43-71(95)120)79(126)102-47-74(123)115-35-18-27-68(115)90(137)138)114(6)73(122)46-101-78(125)60(38-52-19-10-7-11-20-52)106-81(128)61(39-53-21-12-8-13-22-53)108-82(129)63(42-56-44-98-49-103-56)104-72(121)45-100-87(134)75(51(3)117)112-88(135)76(92(4,5)140)113-83(130)62(40-54-23-14-9-15-24-54)107-80(127)59(25-16-34-99-91(96)97)105-77(124)58(93)32-33-70(94)119/h7-15,19-24,28-31,44,49-51,58-69,75-76,117-118,139-140H,16-18,25-27,32-43,45-48,93H2,1-6H3,(H2,94,119)(H2,95,120)(H,98,103)(H,100,134)(H,101,125)(H,102,126)(H,104,121)(H,105,124)(H,106,128)(H,107,127)(H,108,129)(H,109,131)(H,110,133)(H,111,132)(H,112,135)(H,113,130)(H,137,138)(H4,96,97,99)/t51-,58+,59+,60-,61+,62+,63+,64+,65+,66+,67+,68+,69+,75+,76-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 240n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270890
PNG
((2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H]1CCCN1C(=O)[C@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C90H128N24O22S2/c1-48(2)37-57(77(124)106-62(40-52-26-28-54(116)29-27-52)85(132)112-34-13-22-64(112)82(129)108-63(46-137)80(127)104-60(42-69(93)118)75(122)99-45-71(120)111-33-16-25-67(111)88(135)136)105-81(128)65-23-14-35-113(65)87(134)66-24-15-36-114(66)86(133)61(39-51-19-10-7-11-20-51)107-78(125)59(41-53-43-96-47-100-53)101-70(119)44-98-83(130)72(49(3)115)109-84(131)73(90(4,5)138)110-79(126)58(38-50-17-8-6-9-18-50)103-76(123)56(21-12-32-97-89(94)95)102-74(121)55(91)30-31-68(92)117/h6-11,17-20,26-29,43,47-49,55-67,72-73,115-116,137-138H,12-16,21-25,30-42,44-46,91H2,1-5H3,(H2,92,117)(H2,93,118)(H,96,100)(H,98,130)(H,99,122)(H,101,119)(H,102,121)(H,103,123)(H,104,127)(H,105,128)(H,106,124)(H,107,125)(H,108,129)(H,109,131)(H,110,126)(H,135,136)(H4,94,95,97)/t49-,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,65-,66-,67+,72+,73-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 3.30E+3n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270889
PNG
((2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](C)NC(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C92H128N24O22S2/c1-49(2)37-60(81(128)111-66(41-55-28-30-57(118)31-29-55)89(136)116-36-17-26-68(116)86(133)112-67(47-139)85(132)110-65(43-71(95)120)78(125)101-46-73(122)115-35-18-27-69(115)90(137)138)106-76(123)50(3)103-80(127)61(38-52-19-10-7-11-20-52)108-82(129)62(39-53-21-12-8-13-22-53)109-83(130)64(42-56-44-98-48-102-56)104-72(121)45-100-87(134)74(51(4)117)113-88(135)75(92(5,6)140)114-84(131)63(40-54-23-14-9-15-24-54)107-79(126)59(25-16-34-99-91(96)97)105-77(124)58(93)32-33-70(94)119/h7-15,19-24,28-31,44,48-51,58-69,74-75,117-118,139-140H,16-18,25-27,32-43,45-47,93H2,1-6H3,(H2,94,119)(H2,95,120)(H,98,102)(H,100,134)(H,101,125)(H,103,127)(H,104,121)(H,105,124)(H,106,123)(H,107,126)(H,108,129)(H,109,130)(H,110,132)(H,111,128)(H,112,133)(H,113,135)(H,114,131)(H,137,138)(H4,96,97,99)/t50-,51-,58+,59+,60+,61-,62+,63+,64+,65+,66+,67+,68+,69+,74+,75-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 410n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270888
PNG
((2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H]1CCCN1C(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C94H130N24O22S2/c1-51(2)39-61(81(128)111-67(43-56-29-31-58(120)32-30-56)91(138)118-38-17-27-70(118)87(134)113-68(49-141)85(132)109-65(45-73(97)122)79(126)103-48-75(124)116-36-18-28-71(116)92(139)140)110-86(133)69-26-16-37-117(69)90(137)66(42-55-23-13-8-14-24-55)112-82(129)62(40-53-19-9-6-10-20-53)108-83(130)64(44-57-46-100-50-104-57)105-74(123)47-102-88(135)76(52(3)119)114-89(136)77(94(4,5)142)115-84(131)63(41-54-21-11-7-12-22-54)107-80(127)60(25-15-35-101-93(98)99)106-78(125)59(95)33-34-72(96)121/h6-14,19-24,29-32,46,50-52,59-71,76-77,119-120,141-142H,15-18,25-28,33-45,47-49,95H2,1-5H3,(H2,96,121)(H2,97,122)(H,100,104)(H,102,135)(H,103,126)(H,105,123)(H,106,125)(H,107,127)(H,108,130)(H,109,132)(H,110,133)(H,111,128)(H,112,129)(H,113,134)(H,114,136)(H,115,131)(H,139,140)(H4,98,99,101)/t52-,59+,60+,61+,62+,63+,64+,65+,66-,67+,68+,69-,70+,71+,76+,77-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 720n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270887
PNG
((2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2...)
Show SMILES CC(C)C[C@H](NC(=O)[C@H]1CCCN1C(=O)[C@@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C88H126N24O22S2/c1-46(2)35-56(76(123)106-61(38-51-25-27-53(114)28-26-51)85(132)112-34-15-23-64(112)81(128)107-62(44-135)79(126)104-60(40-67(91)116)73(120)97-43-69(118)110-32-16-24-65(110)86(133)134)105-80(127)63-22-14-33-111(63)84(131)47(3)99-75(122)57(36-49-17-9-7-10-18-49)103-77(124)59(39-52-41-94-45-98-52)100-68(117)42-96-82(129)70(48(4)113)108-83(130)71(88(5,6)136)109-78(125)58(37-50-19-11-8-12-20-50)102-74(121)55(21-13-31-95-87(92)93)101-72(119)54(89)29-30-66(90)115/h7-12,17-20,25-28,41,45-48,54-65,70-71,113-114,135-136H,13-16,21-24,29-40,42-44,89H2,1-6H3,(H2,90,115)(H2,91,116)(H,94,98)(H,96,129)(H,97,120)(H,99,122)(H,100,117)(H,101,119)(H,102,121)(H,103,124)(H,104,126)(H,105,127)(H,106,123)(H,107,128)(H,108,130)(H,109,125)(H,133,134)(H4,92,93,95)/t47-,48-,54+,55+,56+,57+,58+,59+,60+,61+,62+,63-,64+,65+,70+,71-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 430n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270886
PNG
((2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H](C)NC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C86H124N24O22S2/c1-44(2)33-55(76(123)105-60(36-50-24-26-52(112)27-25-50)83(130)110-32-15-22-62(110)80(127)106-61(42-133)79(126)104-59(38-65(89)114)73(120)95-41-67(116)109-31-16-23-63(109)84(131)132)101-71(118)46(4)97-70(117)45(3)98-75(122)56(34-48-17-10-8-11-18-48)103-77(124)58(37-51-39-92-43-96-51)99-66(115)40-94-81(128)68(47(5)111)107-82(129)69(86(6,7)134)108-78(125)57(35-49-19-12-9-13-20-49)102-74(121)54(21-14-30-93-85(90)91)100-72(119)53(87)28-29-64(88)113/h8-13,17-20,24-27,39,43-47,53-63,68-69,111-112,133-134H,14-16,21-23,28-38,40-42,87H2,1-7H3,(H2,88,113)(H2,89,114)(H,92,96)(H,94,128)(H,95,120)(H,97,117)(H,98,122)(H,99,115)(H,100,119)(H,101,118)(H,102,121)(H,103,124)(H,104,126)(H,105,123)(H,106,127)(H,107,129)(H,108,125)(H,131,132)(H4,90,91,93)/t45-,46-,47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,68+,69-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 450n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270885
PNG
((2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2...)
Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)[C@@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C85H122N24O22S2/c1-44(2)32-54(75(122)104-59(35-49-23-25-51(111)26-24-49)82(129)109-31-14-21-61(109)79(126)105-60(42-132)78(125)103-58(37-64(88)113)72(119)95-41-67(116)108-30-15-22-62(108)83(130)131)98-65(114)39-93-70(117)45(3)97-74(121)55(33-47-16-9-7-10-17-47)102-76(123)57(36-50-38-91-43-96-50)99-66(115)40-94-80(127)68(46(4)110)106-81(128)69(85(5,6)133)107-77(124)56(34-48-18-11-8-12-19-48)101-73(120)53(20-13-29-92-84(89)90)100-71(118)52(86)27-28-63(87)112/h7-12,16-19,23-26,38,43-46,52-62,68-69,110-111,132-133H,13-15,20-22,27-37,39-42,86H2,1-6H3,(H2,87,112)(H2,88,113)(H,91,96)(H,93,117)(H,94,127)(H,95,119)(H,97,121)(H,98,114)(H,99,115)(H,100,118)(H,101,120)(H,102,123)(H,103,125)(H,104,122)(H,105,126)(H,106,128)(H,107,124)(H,130,131)(H4,89,90,92)/t45-,46-,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,68+,69-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 490n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270916
PNG
((2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S...)
Show SMILES CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCN)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C68H101N17O16S2/c1-38(2)30-51(62(96)79-48(33-42-22-24-43(87)25-23-42)65(99)85-29-15-21-50(85)61(95)80-49(37-102)66(100)101)84(7)54(90)36-83(6)53(89)35-75-58(92)46(31-40-16-10-8-11-17-40)78-59(93)45(26-27-69)76-52(88)34-74-63(97)55(39(3)86)81-64(98)56(68(4,5)103)82-60(94)47(32-41-18-12-9-13-19-41)77-57(91)44(70)20-14-28-73-67(71)72/h8-13,16-19,22-25,38-39,44-51,55-56,86-87,102-103H,14-15,20-21,26-37,69-70H2,1-7H3,(H,74,97)(H,75,92)(H,76,88)(H,77,91)(H,78,93)(H,79,96)(H,80,95)(H,81,98)(H,82,94)(H,100,101)(H4,71,72,73)/t39-,44+,45+,46+,47+,48+,49+,50+,51+,55+,56-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1.20E+3n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270943
PNG
((2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S...)
Show SMILES CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccsc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C71H100N16O16S3/c1-40(2)30-54(65(98)81-51(33-44-22-24-46(89)25-23-44)68(101)87-28-15-21-53(87)64(97)82-52(38-104)69(102)103)86(7)57(92)37-85(6)56(91)36-77-61(94)48(31-42-16-10-8-11-17-42)80-62(95)49(34-45-26-29-106-39-45)78-55(90)35-76-66(99)58(41(3)88)83-67(100)59(71(4,5)105)84-63(96)50(32-43-18-12-9-13-19-43)79-60(93)47(72)20-14-27-75-70(73)74/h8-13,16-19,22-26,29,39-41,47-54,58-59,88-89,104-105H,14-15,20-21,27-28,30-38,72H2,1-7H3,(H,76,99)(H,77,94)(H,78,90)(H,79,93)(H,80,95)(H,81,98)(H,82,97)(H,83,100)(H,84,96)(H,102,103)(H4,73,74,75)/t41-,47+,48+,49+,50+,51+,52+,53+,54+,58+,59-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 2.00E+3n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270942
PNG
((2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S...)
Show SMILES CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccncc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C72H101N17O16S2/c1-41(2)32-55(66(100)83-52(36-45-22-24-47(91)25-23-45)69(103)89-31-15-21-54(89)65(99)84-53(40-106)70(104)105)88(7)58(94)39-87(6)57(93)38-79-62(96)49(33-43-16-10-8-11-17-43)82-63(97)50(35-46-26-29-76-30-27-46)80-56(92)37-78-67(101)59(42(3)90)85-68(102)60(72(4,5)107)86-64(98)51(34-44-18-12-9-13-19-44)81-61(95)48(73)20-14-28-77-71(74)75/h8-13,16-19,22-27,29-30,41-42,48-55,59-60,90-91,106-107H,14-15,20-21,28,31-40,73H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,74,75,77)/t42-,48+,49+,50+,51+,52+,53+,54+,55+,59+,60-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 67n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270941
PNG
((2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S...)
Show SMILES CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cccnc1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C72H101N17O16S2/c1-41(2)31-55(66(100)83-52(34-45-24-26-47(91)27-25-45)69(103)89-30-16-23-54(89)65(99)84-53(40-106)70(104)105)88(7)58(94)39-87(6)57(93)38-79-62(96)49(32-43-17-10-8-11-18-43)82-63(97)50(35-46-21-14-28-76-36-46)80-56(92)37-78-67(101)59(42(3)90)85-68(102)60(72(4,5)107)86-64(98)51(33-44-19-12-9-13-20-44)81-61(95)48(73)22-15-29-77-71(74)75/h8-14,17-21,24-28,36,41-42,48-55,59-60,90-91,106-107H,15-16,22-23,29-35,37-40,73H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,74,75,77)/t42-,48+,49+,50+,51+,52+,53+,54+,55+,59+,60-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 640n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270940
PNG
((2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S...)
Show SMILES CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccn1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C72H101N17O16S2/c1-41(2)32-55(66(100)83-52(35-45-25-27-47(91)28-26-45)69(103)89-31-17-24-54(89)65(99)84-53(40-106)70(104)105)88(7)58(94)39-87(6)57(93)38-79-62(96)49(33-43-18-10-8-11-19-43)82-63(97)51(36-46-22-14-15-29-76-46)80-56(92)37-78-67(101)59(42(3)90)85-68(102)60(72(4,5)107)86-64(98)50(34-44-20-12-9-13-21-44)81-61(95)48(73)23-16-30-77-71(74)75/h8-15,18-22,25-29,41-42,48-55,59-60,90-91,106-107H,16-17,23-24,30-40,73H2,1-7H3,(H,78,101)(H,79,96)(H,80,92)(H,81,95)(H,82,97)(H,83,100)(H,84,99)(H,85,102)(H,86,98)(H,104,105)(H4,74,75,77)/t42-,48+,49+,50+,51+,52+,53+,54+,55+,59+,60-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 330n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270939
PNG
((2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S...)
Show SMILES CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnn[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C69H99N19O16S2/c1-38(2)28-52(63(99)80-49(31-42-22-24-44(90)25-23-42)66(102)88-27-15-21-51(88)62(98)81-50(37-105)67(103)104)87(7)55(93)36-86(6)54(92)35-75-59(95)46(29-40-16-10-8-11-17-40)79-60(96)48(32-43-33-76-85-84-43)77-53(91)34-74-64(100)56(39(3)89)82-65(101)57(69(4,5)106)83-61(97)47(30-41-18-12-9-13-19-41)78-58(94)45(70)20-14-26-73-68(71)72/h8-13,16-19,22-25,33,38-39,45-52,56-57,89-90,105-106H,14-15,20-21,26-32,34-37,70H2,1-7H3,(H,74,100)(H,75,95)(H,77,91)(H,78,94)(H,79,96)(H,80,99)(H,81,98)(H,82,101)(H,83,97)(H,103,104)(H4,71,72,73)(H,76,84,85)/t39-,45+,46+,47+,48+,49+,50+,51+,52+,56+,57-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 320n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270938
PNG
(4-[(2S)-2-{2-[(2S,3R)-2-[(2R)-2-[(2S)-2-[(2S)-2-am...)
Show SMILES CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1csc[n+]1C)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(N)=O
Show InChI InChI=1S/C71H102N18O15S3/c1-40(2)29-54(66(101)82-51(32-44-23-25-46(91)26-24-44)69(104)89-28-16-22-53(89)65(100)83-52(37-105)60(73)95)88(8)57(94)36-86(6)56(93)35-78-62(97)48(30-42-17-11-9-12-18-42)81-63(98)50(33-45-38-107-39-87(45)7)79-55(92)34-77-67(102)58(41(3)90)84-68(103)59(71(4,5)106)85-64(99)49(31-43-19-13-10-14-20-43)80-61(96)47(72)21-15-27-76-70(74)75/h9-14,17-20,23-26,38-41,47-54,58-59,90H,15-16,21-22,27-37,72H2,1-8H3,(H17-,73,74,75,76,77,78,79,80,81,82,83,84,85,91,92,95,96,97,98,99,100,101,102,103,105,106)/p+1/t41-,47+,48+,49+,50+,51+,52+,53+,54+,58+,59-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 110n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270937
PNG
((2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2-(2-{2-[(2S)-2-[(2S...)
Show SMILES CC(C)C[C@H](N(C)C(=O)CN(C)C(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cscn1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C70H99N17O16S3/c1-39(2)28-53(64(98)81-50(31-43-22-24-45(89)25-23-43)67(101)87-27-15-21-52(87)63(97)82-51(36-104)68(102)103)86(7)56(92)35-85(6)55(91)34-76-60(94)47(29-41-16-10-8-11-17-41)80-61(95)49(32-44-37-106-38-77-44)78-54(90)33-75-65(99)57(40(3)88)83-66(100)58(70(4,5)105)84-62(96)48(30-42-18-12-9-13-19-42)79-59(93)46(71)20-14-26-74-69(72)73/h8-13,16-19,22-25,37-40,46-53,57-58,88-89,104-105H,14-15,20-21,26-36,71H2,1-7H3,(H,75,99)(H,76,94)(H,78,90)(H,79,93)(H,80,95)(H,81,98)(H,82,97)(H,83,100)(H,84,96)(H,102,103)(H4,72,73,74)/t40-,46+,47+,48+,49+,50+,51+,52+,53+,57+,58-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 840n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270783
PNG
(CHEMBL508411 | QRFCTGHFGGLYPCNGP)
Show SMILES CC(C)C[C@@H]1NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@@H]2CCCN2C(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O
Show InChI InChI=1S/C82H114N24O22S2/c1-43(2)29-52-73(119)101-57(32-47-20-22-49(108)23-21-47)80(126)106-28-11-18-60(106)78(124)103-58(76(122)100-56(34-63(85)110)71(117)93-39-67(114)105-27-12-19-61(105)81(127)128)40-129-130-41-59(102-74(120)54(31-46-15-8-5-9-16-46)99-72(118)51(17-10-26-89-82(86)87)97-69(115)50(83)24-25-62(84)109)77(123)104-68(44(3)107)79(125)92-38-66(113)96-55(33-48-35-88-42-94-48)75(121)98-53(30-45-13-6-4-7-14-45)70(116)91-36-64(111)90-37-65(112)95-52/h4-9,13-16,20-23,35,42-44,50-61,68,107-108H,10-12,17-19,24-34,36-41,83H2,1-3H3,(H2,84,109)(H2,85,110)(H,88,94)(H,90,111)(H,91,116)(H,92,125)(H,93,117)(H,95,112)(H,96,113)(H,97,115)(H,98,121)(H,99,118)(H,100,122)(H,101,119)(H,102,120)(H,103,124)(H,104,123)(H,127,128)(H4,86,87,89)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 5.70E+3n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270797
PNG
(CHEMBL505689 | RFCTGHFGGLYPC)
Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C66H92N18O16S2/c1-36(2)24-44(58(92)80-48(27-40-18-20-42(86)21-19-40)64(98)84-23-11-17-51(84)62(96)82-50(34-102)65(99)100)76-53(88)31-72-52(87)30-73-57(91)45(25-38-12-6-4-7-13-38)79-60(94)47(28-41-29-70-35-75-41)77-54(89)32-74-63(97)55(37(3)85)83-61(95)49(33-101)81-59(93)46(26-39-14-8-5-9-15-39)78-56(90)43(67)16-10-22-71-66(68)69/h4-9,12-15,18-21,29,35-37,43-51,55,85-86,101-102H,10-11,16-17,22-28,30-34,67H2,1-3H3,(H,70,75)(H,72,87)(H,73,91)(H,74,97)(H,76,88)(H,77,89)(H,78,90)(H,79,94)(H,80,92)(H,81,93)(H,82,96)(H,83,95)(H,99,100)(H4,68,69,71)/t37-,43+,44+,45+,46+,47+,48+,49+,50+,51+,55+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1.00E+4n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270796
PNG
(CHEMBL524509 | QRFCTGHFGGLYPCN)
Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(N)=O
Show InChI InChI=1S/C75H107N23O19S2/c1-39(2)26-49(67(110)94-53(29-43-18-20-45(100)21-19-43)74(117)98-25-11-17-56(98)72(115)96-54(36-118)70(113)91-48(63(79)106)31-58(78)102)88-60(104)34-84-59(103)33-85-65(108)50(27-41-12-6-4-7-13-41)92-69(112)52(30-44-32-82-38-87-44)89-61(105)35-86-73(116)62(40(3)99)97-71(114)55(37-119)95-68(111)51(28-42-14-8-5-9-15-42)93-66(109)47(16-10-24-83-75(80)81)90-64(107)46(76)22-23-57(77)101/h4-9,12-15,18-21,32,38-40,46-56,62,99-100,118-119H,10-11,16-17,22-31,33-37,76H2,1-3H3,(H2,77,101)(H2,78,102)(H2,79,106)(H,82,87)(H,84,103)(H,85,108)(H,86,116)(H,88,104)(H,89,105)(H,90,107)(H,91,113)(H,92,112)(H,93,109)(H,94,110)(H,95,111)(H,96,115)(H,97,114)(H4,80,81,83)/t40-,46+,47+,48+,49+,50+,51+,52+,53+,54+,55+,56+,62+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 6.10E+3n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270795
PNG
(CHEMBL503730 | QRFCTGHFGGLYPCNG)
Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(O)=O
Show InChI InChI=1S/C77H109N23O21S2/c1-40(2)26-49(69(114)96-54(29-44-18-20-46(102)21-19-44)76(121)100-25-11-17-57(100)74(119)98-55(37-122)72(117)95-53(31-59(80)104)67(112)88-36-63(108)109)90-61(106)34-85-60(105)33-86-66(111)50(27-42-12-6-4-7-13-42)93-71(116)52(30-45-32-83-39-89-45)91-62(107)35-87-75(120)64(41(3)101)99-73(118)56(38-123)97-70(115)51(28-43-14-8-5-9-15-43)94-68(113)48(16-10-24-84-77(81)82)92-65(110)47(78)22-23-58(79)103/h4-9,12-15,18-21,32,39-41,47-57,64,101-102,122-123H,10-11,16-17,22-31,33-38,78H2,1-3H3,(H2,79,103)(H2,80,104)(H,83,89)(H,85,105)(H,86,111)(H,87,120)(H,88,112)(H,90,106)(H,91,107)(H,92,110)(H,93,116)(H,94,113)(H,95,117)(H,96,114)(H,97,115)(H,98,119)(H,99,118)(H,108,109)(H4,81,82,84)/t41-,47+,48+,49+,50+,51+,52+,53+,54+,55+,56+,57+,64+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 4.60E+3n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270794
PNG
(CHEMBL526683 | FCTGHFGGLYPCNGP)
Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@@H](N)Cc1ccccc1)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C71H96N18O19S2/c1-38(2)24-46(64(100)84-50(27-42-18-20-44(91)21-19-42)70(106)89-23-10-16-53(89)68(104)86-51(35-109)66(102)83-49(29-55(73)92)63(99)78-34-59(96)88-22-11-17-54(88)71(107)108)80-57(94)32-75-56(93)31-76-62(98)47(26-41-14-8-5-9-15-41)82-65(101)48(28-43-30-74-37-79-43)81-58(95)33-77-69(105)60(39(3)90)87-67(103)52(36-110)85-61(97)45(72)25-40-12-6-4-7-13-40/h4-9,12-15,18-21,30,37-39,45-54,60,90-91,109-110H,10-11,16-17,22-29,31-36,72H2,1-3H3,(H2,73,92)(H,74,79)(H,75,93)(H,76,98)(H,77,105)(H,78,99)(H,80,94)(H,81,95)(H,82,101)(H,83,102)(H,84,100)(H,85,97)(H,86,104)(H,87,103)(H,107,108)/t39-,45+,46+,47+,48+,49+,50+,51+,52+,53+,54+,60+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1.10E+4n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270793
PNG
(CHEMBL207341 | RFCTGHFGGLYPCNGP)
Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](N)CCCN=C(N)N)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C77H108N22O20S2/c1-41(2)27-49(68(110)94-54(30-45-20-22-47(101)23-21-45)75(117)99-26-11-18-57(99)73(115)96-55(38-120)71(113)93-53(32-59(79)102)67(109)87-37-63(106)98-25-12-19-58(98)76(118)119)89-61(104)35-84-60(103)34-85-66(108)50(28-43-13-6-4-7-14-43)92-70(112)52(31-46-33-82-40-88-46)90-62(105)36-86-74(116)64(42(3)100)97-72(114)56(39-121)95-69(111)51(29-44-15-8-5-9-16-44)91-65(107)48(78)17-10-24-83-77(80)81/h4-9,13-16,20-23,33,40-42,48-58,64,100-101,120-121H,10-12,17-19,24-32,34-39,78H2,1-3H3,(H2,79,102)(H,82,88)(H,84,103)(H,85,108)(H,86,116)(H,87,109)(H,89,104)(H,90,105)(H,91,107)(H,92,112)(H,93,113)(H,94,110)(H,95,111)(H,96,115)(H,97,114)(H,118,119)(H4,80,81,83)/t42-,48+,49+,50+,51+,52+,53+,54+,55+,56+,57+,58+,64+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 2.90E+3n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270792
PNG
(CHEMBL498954 | TGHFGGLYP)
Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](N)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C45H61N11O12/c1-25(2)16-31(41(63)55-34(18-28-11-13-30(58)14-12-28)44(66)56-15-7-10-35(56)45(67)68)52-37(60)22-48-36(59)21-49-40(62)32(17-27-8-5-4-6-9-27)54-42(64)33(19-29-20-47-24-51-29)53-38(61)23-50-43(65)39(46)26(3)57/h4-6,8-9,11-14,20,24-26,31-35,39,57-58H,7,10,15-19,21-23,46H2,1-3H3,(H,47,51)(H,48,59)(H,49,62)(H,50,65)(H,52,60)(H,53,61)(H,54,64)(H,55,63)(H,67,68)/t26-,31+,32+,33+,34+,35+,39+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a>2.50E+5n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270791
PNG
(CHEMBL444514 | CTGHFGGLYPC)
Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](N)CS)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C51H71N13O14S2/c1-27(2)16-34(46(72)61-37(18-30-11-13-32(66)14-12-30)50(76)64-15-7-10-39(64)48(74)62-38(25-80)51(77)78)58-41(68)22-54-40(67)21-55-45(71)35(17-29-8-5-4-6-9-29)60-47(73)36(19-31-20-53-26-57-31)59-42(69)23-56-49(75)43(28(3)65)63-44(70)33(52)24-79/h4-6,8-9,11-14,20,26-28,33-39,43,65-66,79-80H,7,10,15-19,21-25,52H2,1-3H3,(H,53,57)(H,54,67)(H,55,71)(H,56,75)(H,58,68)(H,59,69)(H,60,73)(H,61,72)(H,62,74)(H,63,70)(H,77,78)/t28-,33+,34+,35+,36+,37+,38+,39+,43+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 2.00E+4n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270790
PNG
(CHEMBL451944 | QRFCTGHFGGLYPC)
Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(O)=O
Show InChI InChI=1S/C71H100N20O18S2/c1-38(2)26-47(63(101)87-51(29-42-18-20-44(93)21-19-42)69(107)91-25-11-17-54(91)67(105)89-53(36-111)70(108)109)82-57(96)33-78-56(95)32-79-61(99)48(27-40-12-6-4-7-13-40)85-65(103)50(30-43-31-76-37-81-43)83-58(97)34-80-68(106)59(39(3)92)90-66(104)52(35-110)88-64(102)49(28-41-14-8-5-9-15-41)86-62(100)46(16-10-24-77-71(74)75)84-60(98)45(72)22-23-55(73)94/h4-9,12-15,18-21,31,37-39,45-54,59,92-93,110-111H,10-11,16-17,22-30,32-36,72H2,1-3H3,(H2,73,94)(H,76,81)(H,78,95)(H,79,99)(H,80,106)(H,82,96)(H,83,97)(H,84,98)(H,85,103)(H,86,100)(H,87,101)(H,88,102)(H,89,105)(H,90,104)(H,108,109)(H4,74,75,77)/t39-,45+,46+,47+,48+,49+,50+,51+,52+,53+,54+,59+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 4.20E+3n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270789
PNG
(CHEMBL525216 | CTGHFGGLYPCNGP)
Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](N)CS)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C62H87N17O18S2/c1-32(2)19-39(71-49(84)26-66-48(83)25-67-54(88)40(20-34-9-5-4-6-10-34)73-57(91)41(22-36-24-65-31-70-36)72-50(85)27-68-60(94)52(33(3)80)77-53(87)38(63)29-98)56(90)75-43(21-35-13-15-37(81)16-14-35)61(95)79-18-7-11-45(79)59(93)76-44(30-99)58(92)74-42(23-47(64)82)55(89)69-28-51(86)78-17-8-12-46(78)62(96)97/h4-6,9-10,13-16,24,31-33,38-46,52,80-81,98-99H,7-8,11-12,17-23,25-30,63H2,1-3H3,(H2,64,82)(H,65,70)(H,66,83)(H,67,88)(H,68,94)(H,69,89)(H,71,84)(H,72,85)(H,73,91)(H,74,92)(H,75,90)(H,76,93)(H,77,87)(H,96,97)/t33-,38+,39+,40+,41+,42+,43+,44+,45+,46+,52+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 3.40E+4n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270788
PNG
(CHEMBL506507 | QRFCTGHFGGLYPCNGP)
Show SMILES CC(C)C[C@H](NC(=O)CNC(=O)CNC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@H](CS)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C82H116N24O22S2/c1-43(2)29-52(73(119)101-57(32-47-20-22-49(108)23-21-47)80(126)106-28-11-18-60(106)78(124)103-58(40-129)76(122)100-56(34-63(85)110)71(117)93-39-67(114)105-27-12-19-61(105)81(127)128)95-65(112)37-90-64(111)36-91-70(116)53(30-45-13-6-4-7-14-45)98-75(121)55(33-48-35-88-42-94-48)96-66(113)38-92-79(125)68(44(3)107)104-77(123)59(41-130)102-74(120)54(31-46-15-8-5-9-16-46)99-72(118)51(17-10-26-89-82(86)87)97-69(115)50(83)24-25-62(84)109/h4-9,13-16,20-23,35,42-44,50-61,68,107-108,129-130H,10-12,17-19,24-34,36-41,83H2,1-3H3,(H2,84,109)(H2,85,110)(H,88,94)(H,90,111)(H,91,116)(H,92,125)(H,93,117)(H,95,112)(H,96,113)(H,97,115)(H,98,121)(H,99,118)(H,100,122)(H,101,119)(H,102,120)(H,103,124)(H,104,123)(H,127,128)(H4,86,87,89)/t44-,50+,51+,52+,53+,54+,55+,56+,57+,58+,59+,60+,61+,68+/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 5.10E+3n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270787
PNG
(CHEMBL509774 | NSFCRGRPGHFGGCYLF)
Show SMILES CC(C)C[C@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H]1CSSC[C@H](NC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](CO)NC(=O)[C@@H](N)CC(N)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)N[C@@H](CCCN=C(N)N)C(=O)N2CCC[C@H]2C(=O)NCC(=O)N[C@@H](Cc2cnc[nH]2)C(=O)N[C@@H](Cc2ccccc2)C(=O)NCC(=O)NCC(=O)N1)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C86H118N26O21S2/c1-47(2)31-57(75(123)109-62(84(132)133)35-50-19-10-5-11-20-50)105-76(124)60(34-51-24-26-53(114)27-25-51)108-80(128)64-44-134-135-45-65(111-77(125)59(33-49-17-8-4-9-18-49)107-79(127)63(43-113)110-72(120)54(87)37-67(88)115)81(129)104-55(21-12-28-94-85(89)90)73(121)98-41-70(118)101-56(22-13-29-95-86(91)92)83(131)112-30-14-23-66(112)82(130)99-42-71(119)102-61(36-52-38-93-46-100-52)78(126)106-58(32-48-15-6-3-7-16-48)74(122)97-39-68(116)96-40-69(117)103-64/h3-11,15-20,24-27,38,46-47,54-66,113-114H,12-14,21-23,28-37,39-45,87H2,1-2H3,(H2,88,115)(H,93,100)(H,96,116)(H,97,122)(H,98,121)(H,99,130)(H,101,118)(H,102,119)(H,103,117)(H,104,129)(H,105,124)(H,106,126)(H,107,127)(H,108,128)(H,109,123)(H,110,120)(H,111,125)(H,132,133)(H4,89,90,94)(H4,91,92,95)/t54-,55-,56-,57-,58-,59-,60-,61-,62-,63-,64-,65-,66-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 9.40E+3n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270786
PNG
(CHEMBL501558 | PSYCIEGHIDGIYCFNA)
Show SMILES CC[C@H](C)[C@@H]1NC(=O)CNC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](C)C(O)=O)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CO)NC(=O)[C@@H]1CCCN1)[C@@H](C)CC)[C@@H](C)CC
Show InChI InChI=1S/C85H118N20O26S2/c1-8-42(4)68-82(127)98-56(31-48-20-24-51(108)25-21-48)77(122)101-61(80(125)96-54(29-46-15-12-11-13-16-46)75(120)97-58(33-63(86)109)74(119)92-45(7)85(130)131)39-132-133-40-62(102-76(121)55(30-47-18-22-50(107)23-19-47)95-79(124)60(38-106)100-73(118)52-17-14-28-88-52)81(126)105-69(43(5)9-2)83(128)94-53(26-27-66(112)113)71(116)89-36-64(110)93-57(32-49-35-87-41-91-49)78(123)104-70(44(6)10-3)84(129)99-59(34-67(114)115)72(117)90-37-65(111)103-68/h11-13,15-16,18-25,35,41-45,52-62,68-70,88,106-108H,8-10,14,17,26-34,36-40H2,1-7H3,(H2,86,109)(H,87,91)(H,89,116)(H,90,117)(H,92,119)(H,93,110)(H,94,128)(H,95,124)(H,96,125)(H,97,120)(H,98,127)(H,99,129)(H,100,118)(H,101,122)(H,102,121)(H,103,111)(H,104,123)(H,105,126)(H,112,113)(H,114,115)(H,130,131)/t42-,43-,44-,45-,52-,53-,54-,55-,56-,57-,58-,59-,60-,61-,62-,68-,69-,70-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 8.80E+3n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270785
PNG
(CHEMBL503219 | KIICSPGHFGGMYCQGK)
Show SMILES CC[C@H](C)[C@H](NC(=O)[C@@H](N)CCCCN)C(=O)N[C@@H]([C@@H](C)CC)C(=O)N[C@H]1CSSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC(=O)[C@H](CCSC)NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H]2CCCN2C(=O)[C@H](CO)NC1=O)C(=O)N[C@@H](CCC(N)=O)C(=O)NCC(=O)N[C@@H](CCCCN)C(O)=O
Show InChI InChI=1S/C80H122N22O21S3/c1-6-44(3)66(101-78(120)67(45(4)7-2)100-68(110)50(83)18-11-13-28-81)77(119)99-59-42-126-125-41-58(74(116)94-51(25-26-61(84)105)69(111)88-38-64(108)92-53(80(122)123)19-12-14-29-82)98-72(114)55(33-47-21-23-49(104)24-22-47)96-71(113)52(27-31-124-5)91-63(107)37-86-62(106)36-87-70(112)54(32-46-16-9-8-10-17-46)95-73(115)56(34-48-35-85-43-90-48)93-65(109)39-89-76(118)60-20-15-30-102(60)79(121)57(40-103)97-75(59)117/h8-10,16-17,21-24,35,43-45,50-60,66-67,103-104H,6-7,11-15,18-20,25-34,36-42,81-83H2,1-5H3,(H2,84,105)(H,85,90)(H,86,106)(H,87,112)(H,88,111)(H,89,118)(H,91,107)(H,92,108)(H,93,109)(H,94,116)(H,95,115)(H,96,113)(H,97,117)(H,98,114)(H,99,119)(H,100,110)(H,101,120)(H,122,123)/t44-,45-,50-,51-,52-,53-,54-,55-,56-,57-,58-,59-,60-,66-,67-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 2.20E+4n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270784
PNG
(CHEMBL499790 | GGGCVTGHFGGIYCNYQ)
Show SMILES CC[C@H](C)[C@@H]1NC(=O)CNC(=O)CNC(=O)[C@H](Cc2ccccc2)NC(=O)[C@H](Cc2cnc[nH]2)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CSSC[C@H](NC(=O)[C@H](Cc2ccc(O)cc2)NC1=O)C(=O)N[C@@H](CC(N)=O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N[C@@H](CCC(N)=O)C(O)=O)NC(=O)CNC(=O)CNC(=O)CN)C(C)C)[C@H](C)O
Show InChI InChI=1S/C75H103N21O23S2/c1-6-38(4)63-74(117)92-49(24-42-14-18-45(99)19-15-42)67(110)93-53(70(113)91-51(26-55(78)101)69(112)90-48(23-41-12-16-44(98)17-13-41)66(109)88-46(75(118)119)20-21-54(77)100)35-121-120-34-52(87-59(105)31-81-57(103)29-80-56(102)27-76)71(114)95-62(37(2)3)73(116)96-64(39(5)97)72(115)84-33-60(106)86-50(25-43-28-79-36-85-43)68(111)89-47(22-40-10-8-7-9-11-40)65(108)83-30-58(104)82-32-61(107)94-63/h7-19,28,36-39,46-53,62-64,97-99H,6,20-27,29-35,76H2,1-5H3,(H2,77,100)(H2,78,101)(H,79,85)(H,80,102)(H,81,103)(H,82,104)(H,83,108)(H,84,115)(H,86,106)(H,87,105)(H,88,109)(H,89,111)(H,90,112)(H,91,113)(H,92,117)(H,93,110)(H,94,107)(H,95,114)(H,96,116)(H,118,119)/t38-,39-,46-,47-,48-,49-,50-,51-,52-,53-,62-,63-,64-/m0/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 5.20E+3n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50314078
PNG
((5S,8S,15S,18R,23R,26S,32S,35S,38S)-35-benzyl-23-[...)
Show SMILES CC(C)C[C@@H]1N(C)C(=O)CN2CCC[C@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](Cc3cnc[nH]3)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc3ccccc3)NC(=O)[C@H](CCCNC(N)=N)NC(C)=O)C(C)(C)SSC[C@H](NC(=O)[C@@H]3CCCN3C(=O)C(=O)[C@H](Cc3ccc(O)cc3)NC1=O)C(N)=O)[C@@H](C)O)C2=O
Show InChI InChI=1S/C75H103N19O17S2/c1-41(2)31-57-69(107)86-51(32-46-24-26-48(97)27-25-46)61(100)73(111)94-30-16-23-56(94)68(106)89-55(63(76)101)39-112-113-75(5,6)62(91-67(105)53(34-45-19-12-9-13-20-45)87-64(102)49(83-43(4)96)21-14-28-80-74(77)78)71(109)90-60(42(3)95)70(108)81-37-58(98)84-54(35-47-36-79-40-82-47)66(104)88-52(33-44-17-10-8-11-18-44)65(103)85-50-22-15-29-93(72(50)110)38-59(99)92(57)7/h8-13,17-20,24-27,36,40-42,49-57,60,62,95,97H,14-16,21-23,28-35,37-39H2,1-7H3,(H2,76,101)(H,79,82)(H,81,108)(H,83,96)(H,84,98)(H,85,103)(H,86,107)(H,87,102)(H,88,104)(H,89,106)(H,90,109)(H,91,105)(H4,77,78,80)/t42-,49+,50+,51+,52+,53+,54+,55+,56+,57+,60+,62-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 43n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to soluble human FcRn at pH 6 by surface plasmon resonance assay


J Med Chem 53: 1587-96 (2010)


Article DOI: 10.1021/jm901128z
BindingDB Entry DOI: 10.7270/Q23R0T1H
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270896
PNG
((2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2...)
Show SMILES CC(C)C[C@H](NC(=O)CN(C)C(=O)[C@@H](C)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C86H124N24O22S2/c1-45(2)33-55(75(122)104-60(36-50-24-26-52(112)27-25-50)83(130)110-32-15-22-62(110)79(126)105-61(43-133)78(125)103-59(38-65(89)114)72(119)95-41-68(117)109-31-16-23-63(109)84(131)132)99-67(116)42-108(7)82(129)46(3)97-74(121)56(34-48-17-10-8-11-18-48)102-76(123)58(37-51-39-92-44-96-51)98-66(115)40-94-80(127)69(47(4)111)106-81(128)70(86(5,6)134)107-77(124)57(35-49-19-12-9-13-20-49)101-73(120)54(21-14-30-93-85(90)91)100-71(118)53(87)28-29-64(88)113/h8-13,17-20,24-27,39,44-47,53-63,69-70,111-112,133-134H,14-16,21-23,28-38,40-43,87H2,1-7H3,(H2,88,113)(H2,89,114)(H,92,96)(H,94,127)(H,95,119)(H,97,121)(H,98,115)(H,99,116)(H,100,118)(H,101,120)(H,102,123)(H,103,125)(H,104,122)(H,105,126)(H,106,128)(H,107,124)(H,131,132)(H4,90,91,93)/t46-,47-,53+,54+,55+,56+,57+,58+,59+,60+,61+,62+,63+,69+,70-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 190n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270895
PNG
((2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@@H](Cc1ccccc1)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C94H130N24O22S2/c1-51(2)39-61(81(128)111-67(43-56-29-31-58(120)32-30-56)91(138)118-38-17-27-70(118)87(134)113-68(49-141)85(132)109-65(45-73(97)122)79(126)103-48-75(124)116-36-18-28-71(116)92(139)140)110-86(133)69-26-16-37-117(69)90(137)66(42-55-23-13-8-14-24-55)112-82(129)62(40-53-19-9-6-10-20-53)108-83(130)64(44-57-46-100-50-104-57)105-74(123)47-102-88(135)76(52(3)119)114-89(136)77(94(4,5)142)115-84(131)63(41-54-21-11-7-12-22-54)107-80(127)60(25-15-35-101-93(98)99)106-78(125)59(95)33-34-72(96)121/h6-14,19-24,29-32,46,50-52,59-71,76-77,119-120,141-142H,15-18,25-28,33-45,47-49,95H2,1-5H3,(H2,96,121)(H2,97,122)(H,100,104)(H,102,135)(H,103,126)(H,105,123)(H,106,125)(H,107,127)(H,108,130)(H,109,132)(H,110,133)(H,111,128)(H,112,129)(H,113,134)(H,114,136)(H,115,131)(H,139,140)(H4,98,99,101)/t52-,59+,60+,61+,62+,63+,64+,65+,66-,67+,68+,69+,70+,71+,76+,77-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 3.80E+3n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270894
PNG
((2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-[(2S)-2...)
Show SMILES CC(C)C[C@H](NC(=O)[C@@H]1CCCN1C(=O)[C@H]1CCCN1C(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)CNC(=O)[C@@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)[C@@H](C)O)C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C90H128N24O22S2/c1-48(2)37-57(77(124)106-62(40-52-26-28-54(116)29-27-52)85(132)112-34-13-22-64(112)82(129)108-63(46-137)80(127)104-60(42-69(93)118)75(122)99-45-71(120)111-33-16-25-67(111)88(135)136)105-81(128)65-23-14-35-113(65)87(134)66-24-15-36-114(66)86(133)61(39-51-19-10-7-11-20-51)107-78(125)59(41-53-43-96-47-100-53)101-70(119)44-98-83(130)72(49(3)115)109-84(131)73(90(4,5)138)110-79(126)58(38-50-17-8-6-9-18-50)103-76(123)56(21-12-32-97-89(94)95)102-74(121)55(91)30-31-68(92)117/h6-11,17-20,26-29,43,47-49,55-67,72-73,115-116,137-138H,12-16,21-25,30-42,44-46,91H2,1-5H3,(H2,92,117)(H2,93,118)(H,96,100)(H,98,130)(H,99,122)(H,101,119)(H,102,121)(H,103,123)(H,104,127)(H,105,128)(H,106,124)(H,107,125)(H,108,129)(H,109,131)(H,110,126)(H,135,136)(H4,94,95,97)/t49-,55+,56+,57+,58+,59+,60+,61+,62+,63+,64+,65+,66-,67+,72+,73-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a>1.00E+5n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
IgG receptor FcRn large subunit p51


(Homo sapiens)
BDBM50270893
PNG
((2S)-1-{2-[(2S)-2-[(2R)-2-{[(2S)-1-[(2S)-2-{[(2S)-...)
Show SMILES C[C@@H](O)[C@H](NC(=O)[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCCN=C(N)N)NC(=O)[C@@H](N)CCC(N)=O)C(C)(C)S)C(=O)NCC(=O)N[C@@H](Cc1cnc[nH]1)C(=O)N[C@@H](Cc1ccccc1)C(=O)N[C@H](Cc1ccccc1)C(=O)NCC(=O)N1CCC[C@H]1C(=O)N[C@@H](Cc1ccc(O)cc1)C(=O)N1CCC[C@H]1C(=O)N[C@@H](CS)C(=O)N[C@@H](CC(N)=O)C(=O)NCC(=O)N1CCC[C@H]1C(O)=O
Show InChI InChI=1S/C90H122N24O22S2/c1-49(115)73(110-86(133)74(90(2,3)138)111-81(128)60(39-52-21-11-6-12-22-52)105-78(125)57(23-13-33-97-89(94)95)103-75(122)56(91)31-32-68(92)117)85(132)98-44-70(119)102-61(41-54-43-96-48-101-54)80(127)106-59(38-51-19-9-5-10-20-51)79(126)104-58(37-50-17-7-4-8-18-50)76(123)99-45-71(120)112-34-14-24-65(112)83(130)108-63(40-53-27-29-55(116)30-28-53)87(134)114-36-15-25-66(114)84(131)109-64(47-137)82(129)107-62(42-69(93)118)77(124)100-46-72(121)113-35-16-26-67(113)88(135)136/h4-12,17-22,27-30,43,48-49,56-67,73-74,115-116,137-138H,13-16,23-26,31-42,44-47,91H2,1-3H3,(H2,92,117)(H2,93,118)(H,96,101)(H,98,132)(H,99,123)(H,100,124)(H,102,119)(H,103,122)(H,104,126)(H,105,125)(H,106,127)(H,107,129)(H,108,130)(H,109,131)(H,110,133)(H,111,128)(H,135,136)(H4,94,95,97)/t49-,56+,57+,58-,59+,60+,61+,62+,63+,64+,65+,66+,67+,73+,74-/m1/s1
PDB
MMDB

KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
CHEMBL
PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/an/a 1.83E+4n/an/an/a6.0n/a



Syntonix Pharmaceuticals, Inc.

Curated by ChEMBL


Assay Description
Binding affinity to human FcRn at pH 6 by surface plasmon resonance assay


Bioorg Med Chem 16: 6394-405 (2008)


Article DOI: 10.1016/j.bmc.2008.05.004
BindingDB Entry DOI: 10.7270/Q2QV3M9C
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 412 total )  |  Next  |  Last  >>
Jump to: