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Compile Data Set for Download or QSAR

Found 1385 hits Enz. Inhib. hit(s) with Target = 'MAPK-Activated Protein Kinase 2 (MK2)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM175242
PNG
(US9115089, 49)
Show SMILES Cc1cnc(cc1-n1c(C)cc(OCc2ncc(F)cc2F)c(Cl)c1=O)-c1ccnc(n1)C(C)(C)O
Show InChI InChI=1S/C25H22ClF2N5O3/c1-13-10-30-18(17-5-6-29-24(32-17)25(3,4)35)9-20(13)33-14(2)7-21(22(26)23(33)34)36-12-19-16(28)8-15(27)11-31-19/h5-11,35H,12H2,1-4H3
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US Patent
n/an/a 21n/an/an/an/a7.5n/a



CONFLUENCE LIFE SCIENCES, INC.

US Patent


Assay Description
The ability of compounds to inhibit activated phospho-p38alpha is evaluated using a p38alpha /MK2 and a p38alpha /PRAK cascade assay format. The kina...


US Patent US9115089 (2015)


BindingDB Entry DOI: 10.7270/Q25M64H1
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30195
PNG
(Pyrrolopyridine, 26)
Show SMILES FC(F)(F)c1ccc(cc1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1
Show InChI InChI=1S/C19H14F3N3O/c20-19(21,22)13-3-1-11(2-4-13)16-9-12(5-7-23-16)17-10-14-15(25-17)6-8-24-18(14)26/h1-5,7,9-10,25H,6,8H2,(H,24,26)
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n/an/a 71n/an/an/an/a7.530



Pfizer



Assay Description
The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...


J Med Chem 50: 2647-54 (2007)


Article DOI: 10.1021/jm0611004
BindingDB Entry DOI: 10.7270/Q2794313
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30309
PNG
(Pyrrolo-pyrimidone, 2)
Show SMILES Fc1ccc(cc1)-c1cc(ccn1)-c1cc2c(nc[nH]c2=O)[nH]1
Show InChI InChI=1S/C17H11FN4O/c18-12-3-1-10(2-4-12)14-7-11(5-6-19-14)15-8-13-16(22-15)20-9-21-17(13)23/h1-9H,(H2,20,21,22,23)
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n/an/a 1.30E+3n/an/an/an/a7.522



Novartis



Assay Description
For MK2 inhibition, reactions contained compound or vehicle control, hsp27 peptide substrate and activated MK2 mix containing ATP. After incubation, ...


Bioorg Med Chem Lett 18: 6142-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.039
BindingDB Entry DOI: 10.7270/Q2V40SKW
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30310
PNG
(Pyrrolo-pyrimidone, 3)
Show SMILES Fc1cccc(c1)-c1cc(ccn1)-c1cc2c(nc[nH]c2=O)[nH]1
Show InChI InChI=1S/C17H11FN4O/c18-12-3-1-2-10(6-12)14-7-11(4-5-19-14)15-8-13-16(22-15)20-9-21-17(13)23/h1-9H,(H2,20,21,22,23)
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n/an/a 1.23E+3n/an/an/an/a7.522



Novartis



Assay Description
For MK2 inhibition, reactions contained compound or vehicle control, hsp27 peptide substrate and activated MK2 mix containing ATP. After incubation, ...


Bioorg Med Chem Lett 18: 6142-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.039
BindingDB Entry DOI: 10.7270/Q2V40SKW
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30311
PNG
(Pyrrolo-pyrimidone, 4)
Show SMILES COc1ccc(cc1)-c1cc(ccn1)-c1cc2c(nc[nH]c2=O)[nH]1
Show InChI InChI=1S/C18H14N4O2/c1-24-13-4-2-11(3-5-13)15-8-12(6-7-19-15)16-9-14-17(22-16)20-10-21-18(14)23/h2-10H,1H3,(H2,20,21,22,23)
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n/an/a 550n/an/an/an/a7.522



Novartis



Assay Description
For MK2 inhibition, reactions contained compound or vehicle control, hsp27 peptide substrate and activated MK2 mix containing ATP. After incubation, ...


Bioorg Med Chem Lett 18: 6142-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.039
BindingDB Entry DOI: 10.7270/Q2V40SKW
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30312
PNG
(Pyrrolo-pyrimidone, 5)
Show SMILES COc1cccc(c1)-c1cc(ccn1)-c1cc2c(nc[nH]c2=O)[nH]1
Show InChI InChI=1S/C18H14N4O2/c1-24-13-4-2-3-11(7-13)15-8-12(5-6-19-15)16-9-14-17(22-16)20-10-21-18(14)23/h2-10H,1H3,(H2,20,21,22,23)
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n/an/a 5.20E+3n/an/an/an/a7.522



Novartis



Assay Description
For MK2 inhibition, reactions contained compound or vehicle control, hsp27 peptide substrate and activated MK2 mix containing ATP. After incubation, ...


Bioorg Med Chem Lett 18: 6142-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.039
BindingDB Entry DOI: 10.7270/Q2V40SKW
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30313
PNG
(Pyrrolo-pyrimidone, 6)
Show SMILES O=c1[nH]cnc2[nH]c(cc12)-c1ccnc(c1)-c1ccc(CN2CCOCC2)cc1
Show InChI InChI=1S/C22H21N5O2/c28-22-18-12-20(26-21(18)24-14-25-22)17-5-6-23-19(11-17)16-3-1-15(2-4-16)13-27-7-9-29-10-8-27/h1-6,11-12,14H,7-10,13H2,(H2,24,25,26,28)
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n/an/a 1.45E+3n/an/an/an/a7.522



Novartis



Assay Description
For MK2 inhibition, reactions contained compound or vehicle control, hsp27 peptide substrate and activated MK2 mix containing ATP. After incubation, ...


Bioorg Med Chem Lett 18: 6142-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.039
BindingDB Entry DOI: 10.7270/Q2V40SKW
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30314
PNG
(Pyrrolo-pyrimidone, 7)
Show SMILES O=C(NC1CCCC1)c1ccc(cc1)-c1cc(ccn1)-c1cc2c(nc[nH]c2=O)[nH]1
Show InChI InChI=1S/C23H21N5O2/c29-22(27-17-3-1-2-4-17)15-7-5-14(6-8-15)19-11-16(9-10-24-19)20-12-18-21(28-20)25-13-26-23(18)30/h5-13,17H,1-4H2,(H,27,29)(H2,25,26,28,30)
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n/an/a 190n/an/an/an/a7.522



Novartis



Assay Description
For MK2 inhibition, reactions contained compound or vehicle control, hsp27 peptide substrate and activated MK2 mix containing ATP. After incubation, ...


Bioorg Med Chem Lett 18: 6142-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.039
BindingDB Entry DOI: 10.7270/Q2V40SKW
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30315
PNG
(Pyrrolo-pyrimidone, 8)
Show SMILES O=c1[nH]cnc2[nH]c(cc12)-c1ccnc(C=Cc2ccccc2)c1
Show InChI InChI=1S/C19H14N4O/c24-19-16-11-17(23-18(16)21-12-22-19)14-8-9-20-15(10-14)7-6-13-4-2-1-3-5-13/h1-12H,(H2,21,22,23,24)
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n/an/a 170n/an/an/an/a7.522



Novartis



Assay Description
For MK2 inhibition, reactions contained compound or vehicle control, hsp27 peptide substrate and activated MK2 mix containing ATP. After incubation, ...


Bioorg Med Chem Lett 18: 6142-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.039
BindingDB Entry DOI: 10.7270/Q2V40SKW
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30316
PNG
(Pyrrolo-pyrimidone, 9)
Show SMILES Fc1ccc(C=Cc2cc(ccn2)-c2cc3c(nc[nH]c3=O)[nH]2)cc1
Show InChI InChI=1S/C19H13FN4O/c20-14-4-1-12(2-5-14)3-6-15-9-13(7-8-21-15)17-10-16-18(24-17)22-11-23-19(16)25/h1-11H,(H2,22,23,24,25)
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n/an/a 200n/an/an/an/a7.522



Novartis



Assay Description
For MK2 inhibition, reactions contained compound or vehicle control, hsp27 peptide substrate and activated MK2 mix containing ATP. After incubation, ...


Bioorg Med Chem Lett 18: 6142-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.039
BindingDB Entry DOI: 10.7270/Q2V40SKW
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30317
PNG
(Pyrrolo-pyrimidone, 10)
Show SMILES Nc1nc2[nH]c(cc2c(=O)[nH]1)-c1ccnc(C=Cc2ccccc2)c1
Show InChI InChI=1S/C19H15N5O/c20-19-23-17-15(18(25)24-19)11-16(22-17)13-8-9-21-14(10-13)7-6-12-4-2-1-3-5-12/h1-11H,(H4,20,22,23,24,25)
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n/an/a 290n/an/an/an/a7.522



Novartis



Assay Description
For MK2 inhibition, reactions contained compound or vehicle control, hsp27 peptide substrate and activated MK2 mix containing ATP. After incubation, ...


Bioorg Med Chem Lett 18: 6142-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.039
BindingDB Entry DOI: 10.7270/Q2V40SKW
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30318
PNG
(Pyrrolo-pyrimidone, 11)
Show SMILES FC(F)(F)c1nc2[nH]c(cc2c(=O)[nH]1)-c1ccnc(C=Cc2ccccc2)c1
Show InChI InChI=1S/C20H13F3N4O/c21-20(22,23)19-26-17-15(18(28)27-19)11-16(25-17)13-8-9-24-14(10-13)7-6-12-4-2-1-3-5-12/h1-11H,(H2,25,26,27,28)
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n/an/a 1.70E+3n/an/an/an/a7.522



Novartis



Assay Description
For MK2 inhibition, reactions contained compound or vehicle control, hsp27 peptide substrate and activated MK2 mix containing ATP. After incubation, ...


Bioorg Med Chem Lett 18: 6142-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.039
BindingDB Entry DOI: 10.7270/Q2V40SKW
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30319
PNG
(Pyrrolo-pyrimidone, 12)
Show SMILES Cc1nc2[nH]c(cc2c(=O)[nH]1)-c1ccnc(C=Cc2ccccc2)c1
Show InChI InChI=1S/C20H16N4O/c1-13-22-19-17(20(25)23-13)12-18(24-19)15-9-10-21-16(11-15)8-7-14-5-3-2-4-6-14/h2-12H,1H3,(H2,22,23,24,25)
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n/an/a 350n/an/an/an/a7.522



Novartis



Assay Description
For MK2 inhibition, reactions contained compound or vehicle control, hsp27 peptide substrate and activated MK2 mix containing ATP. After incubation, ...


Bioorg Med Chem Lett 18: 6142-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.039
BindingDB Entry DOI: 10.7270/Q2V40SKW
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30320
PNG
(Pyrrolo-pyrimidone, 13)
Show SMILES CCCCc1nc2[nH]c(cc2c(=O)[nH]1)-c1ccnc(C=Cc2ccccc2)c1
Show InChI InChI=1S/C23H22N4O/c1-2-3-9-21-26-22-19(23(28)27-21)15-20(25-22)17-12-13-24-18(14-17)11-10-16-7-5-4-6-8-16/h4-8,10-15H,2-3,9H2,1H3,(H2,25,26,27,28)
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n/an/a 1.26E+3n/an/an/an/a7.522



Novartis



Assay Description
For MK2 inhibition, reactions contained compound or vehicle control, hsp27 peptide substrate and activated MK2 mix containing ATP. After incubation, ...


Bioorg Med Chem Lett 18: 6142-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.039
BindingDB Entry DOI: 10.7270/Q2V40SKW
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30321
PNG
(Pyrrolo-pyrimidone, 14)
Show SMILES O=c1[nH]c(Cc2ccccc2)nc2[nH]c(cc12)-c1ccnc(C=Cc2ccccc2)c1
Show InChI InChI=1S/C26H20N4O/c31-26-22-17-23(28-25(22)29-24(30-26)15-19-9-5-2-6-10-19)20-13-14-27-21(16-20)12-11-18-7-3-1-4-8-18/h1-14,16-17H,15H2,(H2,28,29,30,31)
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n/an/a 340n/an/an/an/a7.522



Novartis



Assay Description
For MK2 inhibition, reactions contained compound or vehicle control, hsp27 peptide substrate and activated MK2 mix containing ATP. After incubation, ...


Bioorg Med Chem Lett 18: 6142-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.039
BindingDB Entry DOI: 10.7270/Q2V40SKW
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30322
PNG
(Pyrrolo-pyrimidone, 15)
Show SMILES O=C(N1CCOCC1)c1ccc(C=Cc2cc(ccn2)-c2cc3c(nc[nH]c3=O)[nH]2)cc1
Show InChI InChI=1S/C24H21N5O3/c30-23-20-14-21(28-22(20)26-15-27-23)18-7-8-25-19(13-18)6-3-16-1-4-17(5-2-16)24(31)29-9-11-32-12-10-29/h1-8,13-15H,9-12H2,(H2,26,27,28,30)
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n/an/a 42n/an/an/an/a7.522



Novartis



Assay Description
For MK2 inhibition, reactions contained compound or vehicle control, hsp27 peptide substrate and activated MK2 mix containing ATP. After incubation, ...


Bioorg Med Chem Lett 18: 6142-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.039
BindingDB Entry DOI: 10.7270/Q2V40SKW
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30323
PNG
(Pyrrolo-pyrimidone, 16)
Show SMILES O=c1[nH]cnc2[nH]c(cc12)-c1ccnc(C=Cc2ccc(CN3CCOCC3)cc2)c1
Show InChI InChI=1S/C24H23N5O2/c30-24-21-14-22(28-23(21)26-16-27-24)19-7-8-25-20(13-19)6-5-17-1-3-18(4-2-17)15-29-9-11-31-12-10-29/h1-8,13-14,16H,9-12,15H2,(H2,26,27,28,30)
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n/an/a 51n/an/an/an/a7.522



Novartis



Assay Description
For MK2 inhibition, reactions contained compound or vehicle control, hsp27 peptide substrate and activated MK2 mix containing ATP. After incubation, ...


Bioorg Med Chem Lett 18: 6142-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.039
BindingDB Entry DOI: 10.7270/Q2V40SKW
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30324
PNG
(Pyrrolo-pyrimidone, 17)
Show SMILES CN(C)CCOc1ccc(C=Cc2cc(ccn2)-c2cc3c(nc[nH]c3=O)[nH]2)cc1
Show InChI InChI=1S/C23H23N5O2/c1-28(2)11-12-30-19-7-4-16(5-8-19)3-6-18-13-17(9-10-24-18)21-14-20-22(27-21)25-15-26-23(20)29/h3-10,13-15H,11-12H2,1-2H3,(H2,25,26,27,29)
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n/an/a 82n/an/an/an/a7.522



Novartis



Assay Description
For MK2 inhibition, reactions contained compound or vehicle control, hsp27 peptide substrate and activated MK2 mix containing ATP. After incubation, ...


Bioorg Med Chem Lett 18: 6142-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.039
BindingDB Entry DOI: 10.7270/Q2V40SKW
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30325
PNG
(Pyrrolo-pyrimidone, 18)
Show SMILES CCN(CC)Cc1ccc(C=Cc2cc(ccn2)-c2cc3c(nc[nH]c3=O)[nH]2)cc1
Show InChI InChI=1S/C24H25N5O/c1-3-29(4-2)15-18-7-5-17(6-8-18)9-10-20-13-19(11-12-25-20)22-14-21-23(28-22)26-16-27-24(21)30/h5-14,16H,3-4,15H2,1-2H3,(H2,26,27,28,30)
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n/an/a 150n/an/an/an/a7.522



Novartis



Assay Description
For MK2 inhibition, reactions contained compound or vehicle control, hsp27 peptide substrate and activated MK2 mix containing ATP. After incubation, ...


Bioorg Med Chem Lett 18: 6142-6 (2008)


Article DOI: 10.1016/j.bmcl.2008.10.039
BindingDB Entry DOI: 10.7270/Q2V40SKW
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM27344
PNG
(2-(pyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,2-c]pyri...)
Show SMILES O=C1NCCc2[nH]c(cc12)-c1ccncc1
Show InChI InChI=1S/C12H11N3O/c16-12-9-7-11(8-1-4-13-5-2-8)15-10(9)3-6-14-12/h1-2,4-5,7,15H,3,6H2,(H,14,16)
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n/an/a 171n/an/an/an/a7.530



Pfizer



Assay Description
The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...


J Med Chem 50: 2647-54 (2007)


Article DOI: 10.1021/jm0611004
BindingDB Entry DOI: 10.7270/Q2794313
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM27388
PNG
(2-(2-chloropyridin-4-yl)-1H,4H,5H,6H,7H-pyrrolo[3,...)
Show SMILES Clc1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1
Show InChI InChI=1S/C12H10ClN3O/c13-11-5-7(1-3-14-11)10-6-8-9(16-10)2-4-15-12(8)17/h1,3,5-6,16H,2,4H2,(H,15,17)
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n/an/a 608n/an/an/an/a7.530



Pfizer



Assay Description
The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...


J Med Chem 50: 2647-54 (2007)


Article DOI: 10.1021/jm0611004
BindingDB Entry DOI: 10.7270/Q2794313
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30178
PNG
(Pyrrolopyridine, 9)
Show SMILES O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1ccccc1
Show InChI InChI=1S/C18H15N3O/c22-18-14-11-17(21-15(14)7-9-20-18)13-6-8-19-16(10-13)12-4-2-1-3-5-12/h1-6,8,10-11,21H,7,9H2,(H,20,22)
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n/an/a 66n/an/an/an/a7.530



Pfizer



Assay Description
The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...


J Med Chem 50: 2647-54 (2007)


Article DOI: 10.1021/jm0611004
BindingDB Entry DOI: 10.7270/Q2794313
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30179
PNG
(Pyrrolopyridine, 10)
Show SMILES O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1ccncc1
Show InChI InChI=1S/C17H14N4O/c22-17-13-10-16(21-14(13)4-8-20-17)12-3-7-19-15(9-12)11-1-5-18-6-2-11/h1-3,5-7,9-10,21H,4,8H2,(H,20,22)
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n/an/a 56n/an/an/an/a7.530



Pfizer



Assay Description
The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...


J Med Chem 50: 2647-54 (2007)


Article DOI: 10.1021/jm0611004
BindingDB Entry DOI: 10.7270/Q2794313
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30180
PNG
(Pyrrolopyridine, 11)
Show SMILES O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1cccnc1
Show InChI InChI=1S/C17H14N4O/c22-17-13-9-16(21-14(13)4-7-20-17)11-3-6-19-15(8-11)12-2-1-5-18-10-12/h1-3,5-6,8-10,21H,4,7H2,(H,20,22)
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n/an/a 48n/an/an/an/a7.530



Pfizer



Assay Description
The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...


J Med Chem 50: 2647-54 (2007)


Article DOI: 10.1021/jm0611004
BindingDB Entry DOI: 10.7270/Q2794313
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30181
PNG
(Pyrrolopyridine, 12)
Show SMILES O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1cncnc1
Show InChI InChI=1S/C16H13N5O/c22-16-12-6-15(21-13(12)2-4-20-16)10-1-3-19-14(5-10)11-7-17-9-18-8-11/h1,3,5-9,21H,2,4H2,(H,20,22)
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n/an/a 83n/an/an/an/a7.530



Pfizer



Assay Description
The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...


J Med Chem 50: 2647-54 (2007)


Article DOI: 10.1021/jm0611004
BindingDB Entry DOI: 10.7270/Q2794313
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30182
PNG
(Pyrrolopyridine, 13)
Show SMILES O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1ccsc1
Show InChI InChI=1S/C16H13N3OS/c20-16-12-8-15(19-13(12)2-5-18-16)10-1-4-17-14(7-10)11-3-6-21-9-11/h1,3-4,6-9,19H,2,5H2,(H,18,20)
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n/an/a 76n/an/an/an/a7.530



Pfizer



Assay Description
The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...


J Med Chem 50: 2647-54 (2007)


Article DOI: 10.1021/jm0611004
BindingDB Entry DOI: 10.7270/Q2794313
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30183
PNG
(Pyrrolopyridine, 14)
Show SMILES O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1ccc2ccccc2c1
Show InChI InChI=1S/C22H17N3O/c26-22-18-13-21(25-19(18)8-10-24-22)17-7-9-23-20(12-17)16-6-5-14-3-1-2-4-15(14)11-16/h1-7,9,11-13,25H,8,10H2,(H,24,26)
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n/an/a 52n/an/an/an/a7.530



Pfizer



Assay Description
The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...


J Med Chem 50: 2647-54 (2007)


Article DOI: 10.1021/jm0611004
BindingDB Entry DOI: 10.7270/Q2794313
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30184
PNG
(Pyrrolopyridine, 15)
Show SMILES O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1cc2ccccc2s1
Show InChI InChI=1S/C20H15N3OS/c24-20-14-11-16(23-15(14)6-8-22-20)12-5-7-21-17(9-12)19-10-13-3-1-2-4-18(13)25-19/h1-5,7,9-11,23H,6,8H2,(H,22,24)
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n/an/a 30n/an/an/an/a7.530



Pfizer



Assay Description
The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...


J Med Chem 50: 2647-54 (2007)


Article DOI: 10.1021/jm0611004
BindingDB Entry DOI: 10.7270/Q2794313
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30185
PNG
(CHEMBL226403 | Pyrrolopyridine, 16)
Show SMILES O=C1NCCc2[nH]c(cc12)-c1ccnc(c1)-c1cnc2ccccc2c1
Show InChI InChI=1S/C21H16N4O/c26-21-16-11-20(25-18(16)6-8-23-21)14-5-7-22-19(10-14)15-9-13-3-1-2-4-17(13)24-12-15/h1-5,7,9-12,25H,6,8H2,(H,23,26)
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n/an/a 8.5n/an/an/an/a7.530



Pfizer



Assay Description
The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...


J Med Chem 50: 2647-54 (2007)


Article DOI: 10.1021/jm0611004
BindingDB Entry DOI: 10.7270/Q2794313
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30186
PNG
(Pyrrolopyridine, 17)
Show SMILES Oc1ccccc1-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1
Show InChI InChI=1S/C18H15N3O2/c22-17-4-2-1-3-12(17)16-9-11(5-7-19-16)15-10-13-14(21-15)6-8-20-18(13)23/h1-5,7,9-10,21-22H,6,8H2,(H,20,23)
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n/an/a 410n/an/an/an/a7.530



Pfizer



Assay Description
The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...


J Med Chem 50: 2647-54 (2007)


Article DOI: 10.1021/jm0611004
BindingDB Entry DOI: 10.7270/Q2794313
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30187
PNG
(Pyrrolopyridine, 18)
Show SMILES Oc1cccc(c1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1
Show InChI InChI=1S/C18H15N3O2/c22-13-3-1-2-11(8-13)16-9-12(4-6-19-16)17-10-14-15(21-17)5-7-20-18(14)23/h1-4,6,8-10,21-22H,5,7H2,(H,20,23)
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n/an/a 25n/an/an/an/a7.530



Pfizer



Assay Description
The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...


J Med Chem 50: 2647-54 (2007)


Article DOI: 10.1021/jm0611004
BindingDB Entry DOI: 10.7270/Q2794313
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30188
PNG
(Pyrrolopyridine, 19)
Show SMILES Oc1ccc(cc1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1
Show InChI InChI=1S/C18H15N3O2/c22-13-3-1-11(2-4-13)16-9-12(5-7-19-16)17-10-14-15(21-17)6-8-20-18(14)23/h1-5,7,9-10,21-22H,6,8H2,(H,20,23)
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n/an/a 21n/an/an/an/a7.530



Pfizer



Assay Description
The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...


J Med Chem 50: 2647-54 (2007)


Article DOI: 10.1021/jm0611004
BindingDB Entry DOI: 10.7270/Q2794313
More data for this
Ligand-Target Pair
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30189
PNG
(Pyrrolopyridine, 20)
Show SMILES Clc1ccccc1-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1
Show InChI InChI=1S/C18H14ClN3O/c19-14-4-2-1-3-12(14)17-9-11(5-7-20-17)16-10-13-15(22-16)6-8-21-18(13)23/h1-5,7,9-10,22H,6,8H2,(H,21,23)
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n/an/a 606n/an/an/an/a7.530



Pfizer



Assay Description
The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...


J Med Chem 50: 2647-54 (2007)


Article DOI: 10.1021/jm0611004
BindingDB Entry DOI: 10.7270/Q2794313
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30190
PNG
(Pyrrolopyridine, 21)
Show SMILES Clc1cccc(c1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1
Show InChI InChI=1S/C18H14ClN3O/c19-13-3-1-2-11(8-13)16-9-12(4-6-20-16)17-10-14-15(22-17)5-7-21-18(14)23/h1-4,6,8-10,22H,5,7H2,(H,21,23)
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n/an/a 37n/an/an/an/a7.530



Pfizer



Assay Description
The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...


J Med Chem 50: 2647-54 (2007)


Article DOI: 10.1021/jm0611004
BindingDB Entry DOI: 10.7270/Q2794313
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30191
PNG
(Pyrrolopyridine, 22)
Show SMILES Clc1ccc(cc1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1
Show InChI InChI=1S/C18H14ClN3O/c19-13-3-1-11(2-4-13)16-9-12(5-7-20-16)17-10-14-15(22-17)6-8-21-18(14)23/h1-5,7,9-10,22H,6,8H2,(H,21,23)
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n/an/a 32n/an/an/an/a7.530



Pfizer



Assay Description
The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...


J Med Chem 50: 2647-54 (2007)


Article DOI: 10.1021/jm0611004
BindingDB Entry DOI: 10.7270/Q2794313
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30192
PNG
(Pyrrolopyridine, 23)
Show SMILES Fc1ccccc1-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1
Show InChI InChI=1S/C18H14FN3O/c19-14-4-2-1-3-12(14)17-9-11(5-7-20-17)16-10-13-15(22-16)6-8-21-18(13)23/h1-5,7,9-10,22H,6,8H2,(H,21,23)
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n/an/a 126n/an/an/an/a7.530



Pfizer



Assay Description
The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...


J Med Chem 50: 2647-54 (2007)


Article DOI: 10.1021/jm0611004
BindingDB Entry DOI: 10.7270/Q2794313
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30193
PNG
(Pyrrolopyridine, 24)
Show SMILES Fc1cccc(c1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1
Show InChI InChI=1S/C18H14FN3O/c19-13-3-1-2-11(8-13)16-9-12(4-6-20-16)17-10-14-15(22-17)5-7-21-18(14)23/h1-4,6,8-10,22H,5,7H2,(H,21,23)
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n/an/a 30n/an/an/an/a7.530



Pfizer



Assay Description
The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...


J Med Chem 50: 2647-54 (2007)


Article DOI: 10.1021/jm0611004
BindingDB Entry DOI: 10.7270/Q2794313
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM30194
PNG
(Pyrrolopyridine, 25)
Show SMILES Fc1ccc(cc1)-c1cc(ccn1)-c1cc2c(CCNC2=O)[nH]1
Show InChI InChI=1S/C18H14FN3O/c19-13-3-1-11(2-4-13)16-9-12(5-7-20-16)17-10-14-15(22-17)6-8-21-18(14)23/h1-5,7,9-10,22H,6,8H2,(H,21,23)
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n/an/a 50n/an/an/an/a7.530



Pfizer



Assay Description
The phosphorylation of HSP27 peptide by MAPKAPK2 was measured using an anion exchange resin capture assay method. The reaction was carried out in rea...


J Med Chem 50: 2647-54 (2007)


Article DOI: 10.1021/jm0611004
BindingDB Entry DOI: 10.7270/Q2794313
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
MAP kinase-activated protein kinase 2


(Homo sapiens (human))
BDBM236557
PNG
(US9365572, 5)
Show SMILES Nc1ccc(cn1)-c1ccc2ncc3c(n(-c4cccc(c4)C(F)(F)F)c(=O)[nH]c3=O)c2n1
Show InChI InChI=1S/C22H13F3N6O2/c23-22(24,25)12-2-1-3-13(8-12)31-19-14(20(32)30-21(31)33)10-27-16-6-5-15(29-18(16)19)11-4-7-17(26)28-9-11/h1-10H,(H2,26,28)(H,30,32,33)
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US Patent
n/an/a>1.00E+4n/an/an/an/a7.528



Xuanzhu Pharma Co., Ltd.

US Patent


Assay Description
Agents: 1-fold kinase buffer without MnCl2: 50 mM HEPES, pH 7.5, 0.0015% Brij-35, 10 mM MgCl2, 2 mM DTT. 1-fold kinase buffer with MnCl2: 50 mM HEPES...


US Patent US9365572 (2016)


BindingDB Entry DOI: 10.7270/Q20C4TNC
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30212
PNG
(carboline analog, 17)
Show SMILES COc1ccc2[nH]c3c(C(C)CNC3=O)c2c1
Show InChI InChI=1S/C13H14N2O2/c1-7-6-14-13(16)12-11(7)9-5-8(17-2)3-4-10(9)15-12/h3-5,7,15H,6H2,1-2H3,(H,14,16)
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n/an/a 4.50E+3n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30213
PNG
(carboline analog, 25)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(OCc4ccccc4)cc3c12
Show InChI InChI=1S/C19H18N2O2/c1-12-10-20-19(22)18-17(12)15-9-14(7-8-16(15)21-18)23-11-13-5-3-2-4-6-13/h2-9,12,21H,10-11H2,1H3,(H,20,22)
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n/an/a>4.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30214
PNG
(carboline analog, 26)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(NC(C)=O)cc3c12
Show InChI InChI=1S/C14H15N3O2/c1-7-6-15-14(19)13-12(7)10-5-9(16-8(2)18)3-4-11(10)17-13/h3-5,7,17H,6H2,1-2H3,(H,15,19)(H,16,18)
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n/an/a>4.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30215
PNG
(carboline analog, 27)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(N)=O
Show InChI InChI=1S/C13H13N3O2/c1-6-5-15-13(18)11-10(6)8-4-7(12(14)17)2-3-9(8)16-11/h2-4,6,16H,5H2,1H3,(H2,14,17)(H,15,18)
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n/an/a 5.40E+3n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30216
PNG
(carboline analog, 28)
Show SMILES CNC(=O)c1ccc2[nH]c3c(C(C)CNC3=O)c2c1
Show InChI InChI=1S/C14H15N3O2/c1-7-6-16-14(19)12-11(7)9-5-8(13(18)15-2)3-4-10(9)17-12/h3-5,7,17H,6H2,1-2H3,(H,15,18)(H,16,19)
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n/an/a 1.20E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30217
PNG
(carboline analog, 29)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)N(C)C
Show InChI InChI=1S/C15H17N3O2/c1-8-7-16-14(19)13-12(8)10-6-9(15(20)18(2)3)4-5-11(10)17-13/h4-6,8,17H,7H2,1-3H3,(H,16,19)
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n/an/a>2.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30218
PNG
(carboline analog, 30)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)NC1CCCCC1
Show InChI InChI=1S/C19H23N3O2/c1-11-10-20-19(24)17-16(11)14-9-12(7-8-15(14)22-17)18(23)21-13-5-3-2-4-6-13/h7-9,11,13,22H,2-6,10H2,1H3,(H,20,24)(H,21,23)
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n/an/a>2.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30219
PNG
(carboline analog, 31)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)N1CCCCC1
Show InChI InChI=1S/C18H21N3O2/c1-11-10-19-17(22)16-15(11)13-9-12(5-6-14(13)20-16)18(23)21-7-3-2-4-8-21/h5-6,9,11,20H,2-4,7-8,10H2,1H3,(H,19,22)
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n/an/a>2.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30220
PNG
(carboline analog, 32)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)Nc1ccccc1
Show InChI InChI=1S/C19H17N3O2/c1-11-10-20-19(24)17-16(11)14-9-12(7-8-15(14)22-17)18(23)21-13-5-3-2-4-6-13/h2-9,11,22H,10H2,1H3,(H,20,24)(H,21,23)
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n/an/a 2.90E+3n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30221
PNG
(carboline analog, 33)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)NCc1ccccc1
Show InChI InChI=1S/C20H19N3O2/c1-12-10-21-20(25)18-17(12)15-9-14(7-8-16(15)23-18)19(24)22-11-13-5-3-2-4-6-13/h2-9,12,23H,10-11H2,1H3,(H,21,25)(H,22,24)
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n/an/a>2.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
MAPK-Activated Protein Kinase 2 (MK2)


(Homo sapiens (human))
BDBM30222
PNG
(carboline analog, 34)
Show SMILES CC1CNC(=O)c2[nH]c3ccc(cc3c12)C(=O)NCCc1ccccc1
Show InChI InChI=1S/C21H21N3O2/c1-13-12-23-21(26)19-18(13)16-11-15(7-8-17(16)24-19)20(25)22-10-9-14-5-3-2-4-6-14/h2-8,11,13,24H,9-10,12H2,1H3,(H,22,25)(H,23,26)
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n/an/a>2.00E+4n/an/an/an/a7.625



Boehringer Ingelheim Pharmaceuticals Inc.



Assay Description
Diluted compounds and activated GST-MK2 were incubated in neutravidin coated plates (Pierce) in reaction buffer containing biotinylated GST-LSP1 and ...


Bioorg Med Chem Lett 17: 4664-9 (2007)


Article DOI: 10.1016/j.bmcl.2007.05.101
BindingDB Entry DOI: 10.7270/Q23N21QP
More data for this
Ligand-Target Pair
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