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Compile Data Set for Download or QSAR

Found 975 hits Enz. Inhib. hit(s) with Target = 'Methionine aminopeptidase 2'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36588
PNG
(AGM-1470)
Show SMILES CO[C@@H]1[C@@H](CC[C@]2(CO2)C1[C@]1(C)OC1CC=C(C)C)OC(=O)NC(=O)CCl
Show InChI InChI=1S/C19H28ClNO6/c1-11(2)5-6-13-18(3,27-13)16-15(24-4)12(7-8-19(16)10-25-19)26-17(23)21-14(22)9-20/h5,12-13,15-16H,6-10H2,1-4H3,(H,21,22,23)/t12-,13?,15-,16?,18-,19+/m1/s1
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n/an/a 1n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36589
PNG
(Ovalicin)
Show SMILES CO[C@@H]1C(=O)CC[C@]2(CO2)[C@@]1(O)[C@]1(C)OC1CC=C(C)C
Show InChI InChI=1S/C16H24O5/c1-10(2)5-6-12-14(3,21-12)16(18)13(19-4)11(17)7-8-15(16)9-20-15/h5,12-13,18H,6-9H2,1-4H3/t12?,13-,14-,15+,16+/m1/s1
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n/an/a 0.400n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36590
PNG
(FOS-72)
Show SMILES CO[C@H]1C([C@]2(C)OC2CC=C(C)C)[C@@]2(CO2)CCC1=O
Show InChI InChI=1S/C16H24O4/c1-10(2)5-6-12-15(3,20-12)14-13(18-4)11(17)7-8-16(14)9-19-16/h5,12-14H,6-9H2,1-4H3/t12?,13-,14?,15-,16+/m1/s1
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n/an/a 6n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36595
PNG
(FOS-68)
Show SMILES CO[C@@H]1[C@@H](CC[C@]2(CO2)[C@@]1(O)[C@]1(C)OC1CC=C(C)C)OC(=O)NC(=O)CCl
Show InChI InChI=1S/C19H28ClNO7/c1-11(2)5-6-13-17(3,28-13)19(24)15(25-4)12(7-8-18(19)10-26-18)27-16(23)21-14(22)9-20/h5,12-13,15,24H,6-10H2,1-4H3,(H,21,22,23)/t12-,13?,15-,17-,18+,19+/m1/s1
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n/an/a 2n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36597
PNG
(FOS-69)
Show SMILES CO[C@@H]1[C@@H](CC[C@]2(CO2)[C@@]1(O)[C@]1(C)OC1CC=C(C)C)OC(=O)CCCCl
Show InChI InChI=1S/C20H31ClO6/c1-13(2)7-8-15-18(3,27-15)20(23)17(24-4)14(9-10-19(20)12-25-19)26-16(22)6-5-11-21/h7,14-15,17,23H,5-6,8-12H2,1-4H3/t14-,15?,17-,18-,19+,20+/m1/s1
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n/an/a 0.100n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36594
PNG
(FOS-202)
Show SMILES CO[C@@H]1[C@H](O)CC[C@](O)(SC)C1[C@]1(C)OC1CC=C(C)C
Show InChI InChI=1S/C16H28O4S/c1-10(2)6-7-12-15(3,20-12)14-13(19-4)11(17)8-9-16(14,18)21-5/h6,11-14,17-18H,7-9H2,1-5H3/t11-,12?,13-,14?,15-,16+/m1/s1
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n/an/a 5.00E+3n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36591
PNG
(FOS-37)
Show SMILES CO[C@@H]1[C@H](O)CC[C@]2(CO2)C1[C@]1(C)OC1CC=C(C)C
Show InChI InChI=1S/C16H26O4/c1-10(2)5-6-12-15(3,20-12)14-13(18-4)11(17)7-8-16(14)9-19-16/h5,11-14,17H,6-9H2,1-4H3/t11-,12?,13-,14?,15-,16+/m1/s1
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n/an/a 8n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36596
PNG
(FOS-34)
Show SMILES CO[C@@H]1[C@H](O)CC[C@]2(CO2)[C@@]1(O)[C@]1(C)OC1CC=C(C)C
Show InChI InChI=1S/C16H26O5/c1-10(2)5-6-12-14(3,21-12)16(18)13(19-4)11(17)7-8-15(16)9-20-15/h5,11-13,17-18H,6-9H2,1-4H3/t11-,12?,13-,14-,15+,16+/m1/s1
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n/an/a 4n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
3D
3D Structure (docked)
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36593
PNG
(FOS-64)
Show SMILES CO[C@@H]1[C@@H](CC[C@](O)(SC)C1[C@]1(C)OC1CC=C(C)C)OC(=O)NC(=O)CCl
Show InChI InChI=1S/C19H30ClNO6S/c1-11(2)6-7-13-18(3,27-13)16-15(25-4)12(8-9-19(16,24)28-5)26-17(23)21-14(22)10-20/h6,12-13,15-16,24H,7-10H2,1-5H3,(H,21,22,23)/t12-,13?,15-,16?,18-,19+/m1/s1
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n/an/a 3.00E+3n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36599
PNG
(FOS-201)
Show SMILES CO[C@@H]1[C@H](O)CC[C@](O)(SC)[C@@]1(O)[C@]1(C)OC1CC=C(C)C
Show InChI InChI=1S/C16H28O5S/c1-10(2)6-7-12-14(3,21-12)16(19)13(20-4)11(17)8-9-15(16,18)22-5/h6,11-13,17-19H,7-9H2,1-5H3/t11-,12?,13-,14-,15+,16+/m1/s1
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n/an/a 45n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM36592
PNG
(FOS-70)
Show SMILES CO[C@@H]1[C@@H](CC[C@]2(CO2)C1[C@]1(C)OC1CC=C(C)C)OC(=O)CCCCl
Show InChI InChI=1S/C20H31ClO5/c1-13(2)7-8-15-19(3,26-15)18-17(23-4)14(9-10-20(18)12-24-20)25-16(22)6-5-11-21/h7,14-15,17-18H,5-6,8-12H2,1-4H3/t14-,15?,17-,18?,19-,20+/m1/s1
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n/an/a 3.5n/an/an/an/a7.3537



Massachusetts Institute of Technology



Assay Description
Enzymatic assay using recombinant human type 2 methionine aminopeptidase (MetAP2).


Chem Biol 4: 461-71 (1997)


Article DOI: 10.1124/jpet.103.062398
BindingDB Entry DOI: 10.7270/Q2NG4P04
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17488
PNG
(2-[(2-{[3-(ethylamino)propyl]amino}benzene)sulfona...)
Show SMILES CCNCCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O
Show InChI InChI=1S/C22H29N3O4S/c1-2-23-14-7-15-24-18-10-5-6-11-20(18)30(28,29)25-19-13-12-16-8-3-4-9-17(16)21(19)22(26)27/h5-6,10-13,23-25H,2-4,7-9,14-15H2,1H3,(H,26,27)
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n/an/a 12n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17489
PNG
(2-{[2-({3-[(2-hydroxyethyl)amino]propyl}amino)benz...)
Show SMILES OCCNCCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O
Show InChI InChI=1S/C22H29N3O5S/c26-15-14-23-12-5-13-24-18-8-3-4-9-20(18)31(29,30)25-19-11-10-16-6-1-2-7-17(16)21(19)22(27)28/h3-4,8-11,23-26H,1-2,5-7,12-15H2,(H,27,28)
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n/an/a 15n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17490
PNG
(2-({2-[(3-{[(tert-butoxy)carbonyl]amino}propyl)ami...)
Show SMILES CC(C)(C)OC(=O)NCCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O
Show InChI InChI=1S/C25H33N3O6S/c1-25(2,3)34-24(31)27-16-8-15-26-19-11-6-7-12-21(19)35(32,33)28-20-14-13-17-9-4-5-10-18(17)22(20)23(29)30/h6-7,11-14,26,28H,4-5,8-10,15-16H2,1-3H3,(H,27,31)(H,29,30)
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n/an/a 77n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17491
PNG
(2-({2-[(3-{[(tert-butoxy)carbonyl](methyl)amino}pr...)
Show SMILES CN(CCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O)C(=O)OC(C)(C)C
Show InChI InChI=1S/C26H35N3O6S/c1-26(2,3)35-25(32)29(4)17-9-16-27-20-12-7-8-13-22(20)36(33,34)28-21-15-14-18-10-5-6-11-19(18)23(21)24(30)31/h7-8,12-15,27-28H,5-6,9-11,16-17H2,1-4H3,(H,30,31)
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n/an/a 110n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17492
PNG
(2-({2-[(3-aminopropyl)amino]benzene}sulfonamido)-5...)
Show SMILES NCCCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O
Show InChI InChI=1S/C20H25N3O4S/c21-12-5-13-22-16-8-3-4-9-18(16)28(26,27)23-17-11-10-14-6-1-2-7-15(14)19(17)20(24)25/h3-4,8-11,22-23H,1-2,5-7,12-13,21H2,(H,24,25)
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n/an/a 13n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17493
PNG
(2-[(2-{[3-(4-methylpiperazin-1-yl)propyl]amino}ben...)
Show SMILES CN1CCN(CCCNc2ccccc2S(=O)(=O)Nc2ccc3CCCCc3c2C(O)=O)CC1
Show InChI InChI=1S/C25H34N4O4S/c1-28-15-17-29(18-16-28)14-6-13-26-21-9-4-5-10-23(21)34(32,33)27-22-12-11-19-7-2-3-8-20(19)24(22)25(30)31/h4-5,9-12,26-27H,2-3,6-8,13-18H2,1H3,(H,30,31)
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n/an/a 26n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17494
PNG
(2-[(2-{[3-(piperidin-1-yl)propyl]amino}benzene)sul...)
Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCCCN2CCCCC2)ccc2CCCCc12
Show InChI InChI=1S/C25H33N3O4S/c29-25(30)24-20-10-3-2-9-19(20)13-14-22(24)27-33(31,32)23-12-5-4-11-21(23)26-15-8-18-28-16-6-1-7-17-28/h4-5,11-14,26-27H,1-3,6-10,15-18H2,(H,29,30)
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n/an/a 20n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17495
PNG
(2-[(2-{[3-(morpholin-4-yl)propyl]amino}benzene)sul...)
Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCCCN2CCOCC2)ccc2CCCCc12
Show InChI InChI=1S/C24H31N3O5S/c28-24(29)23-19-7-2-1-6-18(19)10-11-21(23)26-33(30,31)22-9-4-3-8-20(22)25-12-5-13-27-14-16-32-17-15-27/h3-4,8-11,25-26H,1-2,5-7,12-17H2,(H,28,29)
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n/an/a 22n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17496
PNG
(2-[(2-{[3-(pyrrolidin-1-yl)propyl]amino}benzene)su...)
Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCCCN2CCCC2)ccc2CCCCc12
Show InChI InChI=1S/C24H31N3O4S/c28-24(29)23-19-9-2-1-8-18(19)12-13-21(23)26-32(30,31)22-11-4-3-10-20(22)25-14-7-17-27-15-5-6-16-27/h3-4,10-13,25-26H,1-2,5-9,14-17H2,(H,28,29)
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n/an/a 17n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17497
PNG
(2-[(2-{[2-(1-methylpyrrolidin-2-yl)ethyl]amino}ben...)
Show SMILES CN1CCCC1CCNc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O
Show InChI InChI=1S/C24H31N3O4S/c1-27-16-6-8-18(27)14-15-25-20-10-4-5-11-22(20)32(30,31)26-21-13-12-17-7-2-3-9-19(17)23(21)24(28)29/h4-5,10-13,18,25-26H,2-3,6-9,14-16H2,1H3,(H,28,29)
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n/an/a 17n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17498
PNG
(2-({2-[(1-benzylpiperidin-4-yl)amino]benzene}sulfo...)
Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NC2CCN(Cc3ccccc3)CC2)ccc2CCCCc12
Show InChI InChI=1S/C29H33N3O4S/c33-29(34)28-24-11-5-4-10-22(24)14-15-26(28)31-37(35,36)27-13-7-6-12-25(27)30-23-16-18-32(19-17-23)20-21-8-2-1-3-9-21/h1-3,6-9,12-15,23,30-31H,4-5,10-11,16-20H2,(H,33,34)
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n/an/a 20n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17499
PNG
(2-({2-[(1,2,2,6,6-pentamethylpiperidin-4-yl)amino]...)
Show SMILES CN1C(C)(C)CC(CC1(C)C)Nc1ccccc1S(=O)(=O)Nc1ccc2CCCCc2c1C(O)=O
Show InChI InChI=1S/C27H37N3O4S/c1-26(2)16-19(17-27(3,4)30(26)5)28-21-12-8-9-13-23(21)35(33,34)29-22-15-14-18-10-6-7-11-20(18)24(22)25(31)32/h8-9,12-15,19,28-29H,6-7,10-11,16-17H2,1-5H3,(H,31,32)
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n/an/a 91n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17500
PNG
(2-({2-[(piperidin-3-ylmethyl)amino]benzene}sulfona...)
Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCC2CCCNC2)ccc2CCCCc12
Show InChI InChI=1S/C23H29N3O4S/c27-23(28)22-18-8-2-1-7-17(18)11-12-20(22)26-31(29,30)21-10-4-3-9-19(21)25-15-16-6-5-13-24-14-16/h3-4,9-12,16,24-26H,1-2,5-8,13-15H2,(H,27,28)
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n/an/a 35n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17501
PNG
(2-({2-[(pyrrolidin-3-ylmethyl)amino]benzene}sulfon...)
Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2NCC2CCNC2)ccc2CCCCc12
Show InChI InChI=1S/C22H27N3O4S/c26-22(27)21-17-6-2-1-5-16(17)9-10-19(21)25-30(28,29)20-8-4-3-7-18(20)24-14-15-11-12-23-13-15/h3-4,7-10,15,23-25H,1-2,5-6,11-14H2,(H,26,27)
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n/an/a 34n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


J Med Chem 49: 3832-49 (2006)


Article DOI: 10.1021/jm0601001
BindingDB Entry DOI: 10.7270/Q22V2DDZ
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17586
PNG
(bestatin-type inhibitor, 1 | ethyl (2S)-2-[(2S,3R)...)
Show SMILES CCOC(=O)[C@H](C)NC(=O)[C@@H](O)[C@H](N)CCSC
Show InChI InChI=1S/C11H22N2O4S/c1-4-17-11(16)7(2)13-10(15)9(14)8(12)5-6-18-3/h7-9,14H,4-6,12H2,1-3H3,(H,13,15)/t7-,8+,9-/m0/s1
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n/an/a 6.00E+3n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase activity by monitoring the production of free methionine with L...


Cancer Res 63: 7861-9 (2003)


BindingDB Entry DOI: 10.7270/Q2Z31WXK
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17587
PNG
(bestatin-type inhibitor, 2 | ethyl (2S)-2-[(2S,3R)...)
Show SMILES CCOC(=O)[C@H](C)NC(=O)[C@@H](O)[C@H](N)CCSCC
Show InChI InChI=1S/C12H24N2O4S/c1-4-18-12(17)8(3)14-11(16)10(15)9(13)6-7-19-5-2/h8-10,15H,4-7,13H2,1-3H3,(H,14,16)/t8-,9+,10-/m0/s1
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n/an/a 1.30E+3n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase activity by monitoring the production of free methionine with L...


Cancer Res 63: 7861-9 (2003)


BindingDB Entry DOI: 10.7270/Q2Z31WXK
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17588
PNG
(bestatin-type inhibitor, 3 | ethyl (2S)-2-[(2S,3S)...)
Show SMILES CCOC(=O)[C@H](C)NC(=O)[C@@H](O)[C@H](N)CSCC(C)C
Show InChI InChI=1S/C13H26N2O4S/c1-5-19-13(18)9(4)15-12(17)11(16)10(14)7-20-6-8(2)3/h8-11,16H,5-7,14H2,1-4H3,(H,15,17)/t9-,10+,11-/m0/s1
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n/an/a 1.10E+3n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase activity by monitoring the production of free methionine with L...


Cancer Res 63: 7861-9 (2003)


BindingDB Entry DOI: 10.7270/Q2Z31WXK
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17589
PNG
((2S,3R)-3-amino-5-(ethylsulfanyl)-2-hydroxy-N-[(1S...)
Show SMILES CCSCC[C@@H](N)[C@H](O)C(=O)N[C@@H](C)c1cccc2ccccc12
Show InChI InChI=1S/C19H26N2O2S/c1-3-24-12-11-17(20)18(22)19(23)21-13(2)15-10-6-8-14-7-4-5-9-16(14)15/h4-10,13,17-18,22H,3,11-12,20H2,1-2H3,(H,21,23)/t13-,17+,18-/m0/s1
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n/an/a 22n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase activity by monitoring the production of free methionine with L...


Cancer Res 63: 7861-9 (2003)


BindingDB Entry DOI: 10.7270/Q2Z31WXK
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17590
PNG
((2S,3S)-3-amino-2-hydroxy-4-[(2-methylpropyl)sulfa...)
Show SMILES CC(C)CSC[C@@H](N)[C@H](O)C(=O)N[C@@H](C)c1cccc2ccccc12
Show InChI InChI=1S/C20H28N2O2S/c1-13(2)11-25-12-18(21)19(23)20(24)22-14(3)16-10-6-8-15-7-4-5-9-17(15)16/h4-10,13-14,18-19,23H,11-12,21H2,1-3H3,(H,22,24)/t14-,18+,19-/m0/s1
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n/an/a 48n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase activity by monitoring the production of free methionine with L...


Cancer Res 63: 7861-9 (2003)


BindingDB Entry DOI: 10.7270/Q2Z31WXK
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17591
PNG
((2S,3R)-3-amino-2-hydroxy-N-[(1S)-1-(naphthalen-1-...)
Show SMILES CC(C)SCC[C@@H](N)[C@H](O)C(=O)N[C@@H](C)c1cccc2ccccc12
Show InChI InChI=1S/C20H28N2O2S/c1-13(2)25-12-11-18(21)19(23)20(24)22-14(3)16-10-6-8-15-7-4-5-9-17(15)16/h4-10,13-14,18-19,23H,11-12,21H2,1-3H3,(H,22,24)/t14-,18+,19-/m0/s1
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n/an/a 190n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase activity by monitoring the production of free methionine with L...


Cancer Res 63: 7861-9 (2003)


BindingDB Entry DOI: 10.7270/Q2Z31WXK
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17592
PNG
(CHEMBL169958 | N'-[(2S,3R)-3-amino-5-(ethylsulfany...)
Show SMILES CCSCC[C@@H](N)[C@H](O)C(=O)NNC(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C14H20ClN3O3S/c1-2-22-7-6-11(16)12(19)14(21)18-17-13(20)9-4-3-5-10(15)8-9/h3-5,8,11-12,19H,2,6-7,16H2,1H3,(H,17,20)(H,18,21)/t11-,12+/m1/s1
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n/an/a 110n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase activity by monitoring the production of free methionine with L...


Cancer Res 63: 7861-9 (2003)


BindingDB Entry DOI: 10.7270/Q2Z31WXK
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17593
PNG
(CHEMBL170733 | N'-[(2S,3S)-3-amino-2-hydroxy-4-[(2...)
Show SMILES CC(C)CSC[C@@H](N)[C@H](O)C(=O)NNC(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C15H22ClN3O3S/c1-9(2)7-23-8-12(17)13(20)15(22)19-18-14(21)10-4-3-5-11(16)6-10/h3-6,9,12-13,20H,7-8,17H2,1-2H3,(H,18,21)(H,19,22)/t12-,13+/m1/s1
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n/an/a 130n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase activity by monitoring the production of free methionine with L...


Cancer Res 63: 7861-9 (2003)


BindingDB Entry DOI: 10.7270/Q2Z31WXK
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17594
PNG
(A-357300 | CHEMBL352764 | N'-[(2S,3R)-3-amino-2-hy...)
Show SMILES CC(C)SCC[C@@H](N)[C@H](O)C(=O)NNC(=O)c1cccc(Cl)c1
Show InChI InChI=1S/C15H22ClN3O3S/c1-9(2)23-7-6-12(17)13(20)15(22)19-18-14(21)10-4-3-5-11(16)8-10/h3-5,8-9,12-13,20H,6-7,17H2,1-2H3,(H,18,21)(H,19,22)/t12-,13+/m1/s1
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n/an/a 120n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase activity by monitoring the production of free methionine with L...


Cancer Res 63: 7861-9 (2003)


BindingDB Entry DOI: 10.7270/Q2Z31WXK
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17595
PNG
(5-bromo-2-[(4-chlorobenzene)sulfonamido]benzoic ac...)
Show SMILES OC(=O)c1cc(Br)ccc1NS(=O)(=O)c1ccc(Cl)cc1
Show InChI InChI=1S/C13H9BrClNO4S/c14-8-1-6-12(11(7-8)13(17)18)16-21(19,20)10-4-2-9(15)3-5-10/h1-7,16H,(H,17,18)
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n/an/a 9.10E+3n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 16: 3574-7 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.085
BindingDB Entry DOI: 10.7270/Q2TB1556
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17596
PNG
(2-(2,1,3-benzothiadiazole-4-sulfonamido)-5-bromobe...)
Show SMILES OC(=O)c1cc(Br)ccc1NS(=O)(=O)c1cccc2nsnc12
Show InChI InChI=1S/C13H8BrN3O4S2/c14-7-4-5-9(8(6-7)13(18)19)17-23(20,21)11-3-1-2-10-12(11)16-22-15-10/h1-6,17H,(H,18,19)
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n/an/a 3.90E+3n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 16: 3574-7 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.085
BindingDB Entry DOI: 10.7270/Q2TB1556
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17597
PNG
(2-[(4-chlorobenzene)sulfonamido]-5-methylbenzoic a...)
Show SMILES Cc1ccc(NS(=O)(=O)c2ccc(Cl)cc2)c(c1)C(O)=O
Show InChI InChI=1S/C14H12ClNO4S/c1-9-2-7-13(12(8-9)14(17)18)16-21(19,20)11-5-3-10(15)4-6-11/h2-8,16H,1H3,(H,17,18)
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n/an/a 1.10E+4n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 16: 3574-7 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.085
BindingDB Entry DOI: 10.7270/Q2TB1556
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17477
PNG
(2-benzenesulfonamido-5-methylbenzoic acid | A44414...)
Show SMILES Cc1ccc(NS(=O)(=O)c2ccccc2)c(c1)C(O)=O
Show InChI InChI=1S/C14H13NO4S/c1-10-7-8-13(12(9-10)14(16)17)15-20(18,19)11-5-3-2-4-6-11/h2-9,15H,1H3,(H,16,17)
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n/an/a 1.00E+3n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 16: 3574-7 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.085
BindingDB Entry DOI: 10.7270/Q2TB1556
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17599
PNG
(2-benzenesulfonamido-3,5-dimethylbenzoic acid | su...)
Show SMILES Cc1cc(C)c(NS(=O)(=O)c2ccccc2)c(c1)C(O)=O
Show InChI InChI=1S/C15H15NO4S/c1-10-8-11(2)14(13(9-10)15(17)18)16-21(19,20)12-6-4-3-5-7-12/h3-9,16H,1-2H3,(H,17,18)
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n/an/a 350n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 16: 3574-7 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.085
BindingDB Entry DOI: 10.7270/Q2TB1556
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17600
PNG
(2-benzenesulfonamido-5-ethylbenzoic acid | sulfona...)
Show SMILES CCc1ccc(NS(=O)(=O)c2ccccc2)c(c1)C(O)=O
Show InChI InChI=1S/C15H15NO4S/c1-2-11-8-9-14(13(10-11)15(17)18)16-21(19,20)12-6-4-3-5-7-12/h3-10,16H,2H2,1H3,(H,17,18)
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n/an/a 90n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 16: 3574-7 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.085
BindingDB Entry DOI: 10.7270/Q2TB1556
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17601
PNG
(2-benzenesulfonamido-5-propylbenzoic acid | sulfon...)
Show SMILES CCCc1ccc(NS(=O)(=O)c2ccccc2)c(c1)C(O)=O
Show InChI InChI=1S/C16H17NO4S/c1-2-6-12-9-10-15(14(11-12)16(18)19)17-22(20,21)13-7-4-3-5-8-13/h3-5,7-11,17H,2,6H2,1H3,(H,18,19)
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n/an/a 1.10E+3n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 16: 3574-7 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.085
BindingDB Entry DOI: 10.7270/Q2TB1556
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17602
PNG
(2-benzenesulfonamido-5-butylbenzoic acid | sulfona...)
Show SMILES CCCCc1ccc(NS(=O)(=O)c2ccccc2)c(c1)C(O)=O
Show InChI InChI=1S/C17H19NO4S/c1-2-3-7-13-10-11-16(15(12-13)17(19)20)18-23(21,22)14-8-5-4-6-9-14/h4-6,8-12,18H,2-3,7H2,1H3,(H,19,20)
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n/an/a 1.00E+4n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 16: 3574-7 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.085
BindingDB Entry DOI: 10.7270/Q2TB1556
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17603
PNG
(2-benzenesulfonamidonaphthalene-1-carboxylic acid ...)
Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2)ccc2ccccc12
Show InChI InChI=1S/C17H13NO4S/c19-17(20)16-14-9-5-4-6-12(14)10-11-15(16)18-23(21,22)13-7-2-1-3-8-13/h1-11,18H,(H,19,20)
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n/an/a 19n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 16: 3574-7 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.085
BindingDB Entry DOI: 10.7270/Q2TB1556
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17604
PNG
(2-[(4-fluorobenzene)sulfonamido]naphthalene-1-carb...)
Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccc(F)cc2)ccc2ccccc12
Show InChI InChI=1S/C17H12FNO4S/c18-12-6-8-13(9-7-12)24(22,23)19-15-10-5-11-3-1-2-4-14(11)16(15)17(20)21/h1-10,19H,(H,20,21)
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n/an/a 15n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 16: 3574-7 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.085
BindingDB Entry DOI: 10.7270/Q2TB1556
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17478
PNG
(2-benzenesulfonamido-5,6,7,8-tetrahydronaphthalene...)
Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccccc2)ccc2CCCCc12
Show InChI InChI=1S/C17H17NO4S/c19-17(20)16-14-9-5-4-6-12(14)10-11-15(16)18-23(21,22)13-7-2-1-3-8-13/h1-3,7-8,10-11,18H,4-6,9H2,(H,19,20)
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n/an/a 9n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 16: 3574-7 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.085
BindingDB Entry DOI: 10.7270/Q2TB1556
More data for this
Ligand-Target Pair
3D
3D Structure (crystal)
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17606
PNG
(2-[(4-fluorobenzene)sulfonamido]-8-methyl-5,6-dihy...)
Show SMILES CC1=CCCc2ccc(NS(=O)(=O)c3ccc(F)cc3)c(C(O)=O)c12
Show InChI InChI=1S/C18H16FNO4S/c1-11-3-2-4-12-5-10-15(17(16(11)12)18(21)22)20-25(23,24)14-8-6-13(19)7-9-14/h3,5-10,20H,2,4H2,1H3,(H,21,22)
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n/an/a 20n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 16: 3574-7 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.085
BindingDB Entry DOI: 10.7270/Q2TB1556
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17607
PNG
(2-[(4-fluorobenzene)sulfonamido]-5,6,7,8-tetrahydr...)
Show SMILES OC(=O)c1c(NS(=O)(=O)c2ccc(F)cc2)ccc2CCCCc12
Show InChI InChI=1S/C17H16FNO4S/c18-12-6-8-13(9-7-12)24(22,23)19-15-10-5-11-3-1-2-4-14(11)16(15)17(20)21/h5-10,19H,1-4H2,(H,20,21)
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n/an/a 10n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 16: 3574-7 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.085
BindingDB Entry DOI: 10.7270/Q2TB1556
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17608
PNG
((8S)-2-[(4-fluorobenzene)sulfonamido]-8-methyl-5,6...)
Show SMILES C[C@H]1CCCc2ccc(NS(=O)(=O)c3ccc(F)cc3)c(C(O)=O)c12
Show InChI InChI=1S/C18H18FNO4S/c1-11-3-2-4-12-5-10-15(17(16(11)12)18(21)22)20-25(23,24)14-8-6-13(19)7-9-14/h5-11,20H,2-4H2,1H3,(H,21,22)/t11-/m0/s1
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n/an/a 27n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 16: 3574-7 (2006)


Article DOI: 10.1016/j.bmcl.2006.03.085
BindingDB Entry DOI: 10.7270/Q2TB1556
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17609
PNG
(5,6-disubstituted anthranilic acid sulfonamide, 9a...)
Show SMILES Cc1ccc(NS(=O)(=O)c2ccc(F)cc2)c(C(O)=O)c1C
Show InChI InChI=1S/C15H14FNO4S/c1-9-3-8-13(14(10(9)2)15(18)19)17-22(20,21)12-6-4-11(16)5-7-12/h3-8,17H,1-2H3,(H,18,19)
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n/an/a 78n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
Methionine aminopeptidase 2


(Homo sapiens (human))
BDBM17610
PNG
(3-ethenyl-6-[(4-fluorobenzene)sulfonamido]-2-methy...)
Show SMILES Cc1c(C=C)ccc(NS(=O)(=O)c2ccc(F)cc2)c1C(O)=O
Show InChI InChI=1S/C16H14FNO4S/c1-3-11-4-9-14(15(10(11)2)16(19)20)18-23(21,22)13-7-5-12(17)6-8-13/h3-9,18H,1H2,2H3,(H,19,20)
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n/an/a 60n/an/an/an/a7.422



Abbott Laboratories



Assay Description
A coupled enzyme chromogenic assay was developed to measure methionine aminopeptidase-2 activity by monitoring the production of free methionine with...


Bioorg Med Chem Lett 17: 2817-22 (2007)


Article DOI: 10.1016/j.bmcl.2007.02.062
BindingDB Entry DOI: 10.7270/Q2PK0DD1
More data for this
Ligand-Target Pair
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