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Compile Data Set for Download or QSAR

Found 416 hits Enz. Inhib. hit(s) with Target = 'Monoglyceride Lipase (MGL)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Monoglyceride Lipase (MGL)


(Mus musculus (mouse))
BDBM26736
PNG
(CHEMBL509860 | LY2183240 | N,N-dimethyl-5-[(4-phen...)
Show SMILES CN(C)C(=O)n1nnnc1Cc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C17H17N5O/c1-21(2)17(23)22-16(18-19-20-22)12-13-8-10-15(11-9-13)14-6-4-3-5-7-14/h3-11H,12H2,1-2H3
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n/an/a 5.30n/an/an/an/a7.422



The Scripps Research Institute



Assay Description
Serine hydrolase targets were recombinantly expressed in COS-7 cells by transient transfection. IC50 values were obtained by competitive ABPP with F...


J Am Chem Soc 128: 9699-704 (2006)


Article DOI: 10.1021/ja062999h
BindingDB Entry DOI: 10.7270/Q20K26VX
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM50128581
PNG
(Biphenyl-3-yl-carbamic acid cyclohexyl ester | CHE...)
Show SMILES O=C(Nc1cccc(c1)-c1ccccc1)OC1CCCCC1
Show InChI InChI=1S/C19H21NO2/c21-19(22-18-12-5-2-6-13-18)20-17-11-7-10-16(14-17)15-8-3-1-4-9-15/h1,3-4,7-11,14,18H,2,5-6,12-13H2,(H,20,21)
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n/an/a 2.23E+5n/an/an/an/a8.0n/a



University of California, Irvine



Assay Description
The measurement of the ability of URB602 compound to inhibit MGL activity.


Chem Biol 14: 1357-65 (2007)


Article DOI: 10.1016/j.chembiol.2007.10.017
BindingDB Entry DOI: 10.7270/Q2XS5SW0
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM81326
PNG
(URB602, 6)
Show SMILES O=C(Nc1cccc(c1)-c1ccccc1)SC1CCCCC1
Show InChI InChI=1S/C19H21NOS/c21-19(22-18-12-5-2-6-13-18)20-17-11-7-10-16(14-17)15-8-3-1-4-9-15/h1,3-4,7-11,14,18H,2,5-6,12-13H2,(H,20,21)
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n/an/a>3.00E+5n/an/an/an/a8.0n/a



University of California, Irvine



Assay Description
The measurement of the ability of URB602 compound to inhibit MGL activity.


Chem Biol 14: 1357-65 (2007)


Article DOI: 10.1016/j.chembiol.2007.10.017
BindingDB Entry DOI: 10.7270/Q2XS5SW0
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM81325
PNG
(URB602, 5)
Show SMILES O=C(CC1CCCCC1)Nc1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C20H23NO/c22-20(14-16-8-3-1-4-9-16)21-19-13-7-12-18(15-19)17-10-5-2-6-11-17/h2,5-7,10-13,15-16H,1,3-4,8-9,14H2,(H,21,22)
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n/an/a>3.00E+5n/an/an/an/a8.0n/a



University of California, Irvine



Assay Description
The measurement of the ability of URB602 compound to inhibit MGL activity.


Chem Biol 14: 1357-65 (2007)


Article DOI: 10.1016/j.chembiol.2007.10.017
BindingDB Entry DOI: 10.7270/Q2XS5SW0
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM81311
PNG
(URB602, 3a)
Show SMILES O=C(NCCCCCc1ccccc1)OC1CCCCC1
Show InChI InChI=1S/C18H27NO2/c20-18(21-17-13-7-2-8-14-17)19-15-9-3-6-12-16-10-4-1-5-11-16/h1,4-5,10-11,17H,2-3,6-9,12-15H2,(H,19,20)
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n/an/a>3.00E+5n/an/an/an/a8.0n/a



University of California, Irvine



Assay Description
The measurement of the ability of URB602 compound to inhibit MGL activity.


Chem Biol 14: 1357-65 (2007)


Article DOI: 10.1016/j.chembiol.2007.10.017
BindingDB Entry DOI: 10.7270/Q2XS5SW0
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM81312
PNG
(URB602, 3b)
Show SMILES O=C(Nc1ccccc1)OC1CCCCC1
Show InChI InChI=1S/C13H17NO2/c15-13(14-11-7-3-1-4-8-11)16-12-9-5-2-6-10-12/h1,3-4,7-8,12H,2,5-6,9-10H2,(H,14,15)
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n/an/a>3.00E+5n/an/an/an/a8.0n/a



University of California, Irvine



Assay Description
The measurement of the ability of URB602 compound to inhibit MGL activity.


Chem Biol 14: 1357-65 (2007)


Article DOI: 10.1016/j.chembiol.2007.10.017
BindingDB Entry DOI: 10.7270/Q2XS5SW0
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM81313
PNG
(URB602, 3c)
Show SMILES O=C(Nc1cccc(c1)-c1ccccc1)OCCCCCc1ccccc1
Show InChI InChI=1S/C24H25NO2/c26-24(27-18-9-3-6-13-20-11-4-1-5-12-20)25-23-17-10-16-22(19-23)21-14-7-2-8-15-21/h1-2,4-5,7-8,10-12,14-17,19H,3,6,9,13,18H2,(H,25,26)
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n/an/a>3.00E+5n/an/an/an/a8.0n/a



University of California, Irvine



Assay Description
The measurement of the ability of URB602 compound to inhibit MGL activity.


Chem Biol 14: 1357-65 (2007)


Article DOI: 10.1016/j.chembiol.2007.10.017
BindingDB Entry DOI: 10.7270/Q2XS5SW0
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM81314
PNG
(URB602, 3d)
Show SMILES Cc1cccc(c1)-c1cccc(NC(=O)OC2CCCCC2)c1
Show InChI InChI=1S/C20H23NO2/c1-15-7-5-8-16(13-15)17-9-6-10-18(14-17)21-20(22)23-19-11-3-2-4-12-19/h5-10,13-14,19H,2-4,11-12H2,1H3,(H,21,22)
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n/an/a>3.00E+5n/an/an/an/a8.0n/a



University of California, Irvine



Assay Description
The measurement of the ability of URB602 compound to inhibit MGL activity.


Chem Biol 14: 1357-65 (2007)


Article DOI: 10.1016/j.chembiol.2007.10.017
BindingDB Entry DOI: 10.7270/Q2XS5SW0
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM81315
PNG
(URB602, 3e)
Show SMILES FC(F)(F)c1cccc(c1)-c1cccc(NC(=O)OC2CCCCC2)c1
Show InChI InChI=1S/C20H20F3NO2/c21-20(22,23)16-8-4-6-14(12-16)15-7-5-9-17(13-15)24-19(25)26-18-10-2-1-3-11-18/h4-9,12-13,18H,1-3,10-11H2,(H,24,25)
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n/an/a>3.00E+5n/an/an/an/a8.0n/a



University of California, Irvine



Assay Description
The measurement of the ability of URB602 compound to inhibit MGL activity.


Chem Biol 14: 1357-65 (2007)


Article DOI: 10.1016/j.chembiol.2007.10.017
BindingDB Entry DOI: 10.7270/Q2XS5SW0
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM81316
PNG
(URB602, 3f)
Show SMILES O=C(Nc1cccc(Oc2cccc(c2)-c2ccccc2)c1)OC1CCCCC1
Show InChI InChI=1S/C25H25NO3/c27-25(29-22-13-5-2-6-14-22)26-21-12-8-16-24(18-21)28-23-15-7-11-20(17-23)19-9-3-1-4-10-19/h1,3-4,7-12,15-18,22H,2,5-6,13-14H2,(H,26,27)
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n/an/a>3.00E+5n/an/an/an/a8.0n/a



University of California, Irvine



Assay Description
The measurement of the ability of URB602 compound to inhibit MGL activity.


Chem Biol 14: 1357-65 (2007)


Article DOI: 10.1016/j.chembiol.2007.10.017
BindingDB Entry DOI: 10.7270/Q2XS5SW0
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM81317
PNG
(URB602, 3g)
Show SMILES O=C(Nc1ccccc1-c1ccccc1)OC1CCCCC1
Show InChI InChI=1S/C19H21NO2/c21-19(22-16-11-5-2-6-12-16)20-18-14-8-7-13-17(18)15-9-3-1-4-10-15/h1,3-4,7-10,13-14,16H,2,5-6,11-12H2,(H,20,21)
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n/an/a>3.00E+5n/an/an/an/a8.0n/a



University of California, Irvine



Assay Description
The measurement of the ability of URB602 compound to inhibit MGL activity.


Chem Biol 14: 1357-65 (2007)


Article DOI: 10.1016/j.chembiol.2007.10.017
BindingDB Entry DOI: 10.7270/Q2XS5SW0
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM81318
PNG
(URB602, 3h)
Show SMILES OCC(O)COC(=O)Nc1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C16H17NO4/c18-10-15(19)11-21-16(20)17-14-8-4-7-13(9-14)12-5-2-1-3-6-12/h1-9,15,18-19H,10-11H2,(H,17,20)
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n/an/a>3.00E+5n/an/an/an/a8.0n/a



University of California, Irvine



Assay Description
The measurement of the ability of URB602 compound to inhibit MGL activity.


Chem Biol 14: 1357-65 (2007)


Article DOI: 10.1016/j.chembiol.2007.10.017
BindingDB Entry DOI: 10.7270/Q2XS5SW0
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM81319
PNG
(URB602, 3i)
Show SMILES CC1(C)OCC(CO1)OC(=O)Nc1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C19H21NO4/c1-19(2)22-12-17(13-23-19)24-18(21)20-16-10-6-9-15(11-16)14-7-4-3-5-8-14/h3-11,17H,12-13H2,1-2H3,(H,20,21)
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n/an/a>3.00E+5n/an/an/an/a8.0n/a



University of California, Irvine



Assay Description
The measurement of the ability of URB602 compound to inhibit MGL activity.


Chem Biol 14: 1357-65 (2007)


Article DOI: 10.1016/j.chembiol.2007.10.017
BindingDB Entry DOI: 10.7270/Q2XS5SW0
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM50271028
PNG
(Biphenyl-3-ylcarbamic Acid Biphenyl-3-yl Ester | C...)
Show SMILES O=C(Nc1cccc(c1)-c1ccccc1)Oc1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C25H19NO2/c27-25(26-23-15-7-13-21(17-23)19-9-3-1-4-10-19)28-24-16-8-14-22(18-24)20-11-5-2-6-12-20/h1-18H,(H,26,27)
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n/an/a>3.00E+5n/an/an/an/a8.0n/a



University of California, Irvine



Assay Description
The measurement of the ability of URB602 compound to inhibit MGL activity.


Chem Biol 14: 1357-65 (2007)


Article DOI: 10.1016/j.chembiol.2007.10.017
BindingDB Entry DOI: 10.7270/Q2XS5SW0
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM50295655
PNG
(CHEMBL541244 | URB602, 3k | cyclohexyl biphenyl-4-...)
Show SMILES O=C(Nc1ccc(cc1)-c1ccccc1)OC1CCCCC1
Show InChI InChI=1S/C19H21NO2/c21-19(22-18-9-5-2-6-10-18)20-17-13-11-16(12-14-17)15-7-3-1-4-8-15/h1,3-4,7-8,11-14,18H,2,5-6,9-10H2,(H,20,21)
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n/an/a>3.00E+5n/an/an/an/a8.0n/a



University of California, Irvine



Assay Description
The measurement of the ability of URB602 compound to inhibit MGL activity.


Chem Biol 14: 1357-65 (2007)


Article DOI: 10.1016/j.chembiol.2007.10.017
BindingDB Entry DOI: 10.7270/Q2XS5SW0
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM81320
PNG
(URB602, 3l)
Show SMILES O=C(Nc1cccc(c1)-c1ccccc1)Oc1ccccc1
Show InChI InChI=1S/C19H15NO2/c21-19(22-18-12-5-2-6-13-18)20-17-11-7-10-16(14-17)15-8-3-1-4-9-15/h1-14H,(H,20,21)
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n/an/a 2.43E+5n/an/an/an/a8.0n/a



University of California, Irvine



Assay Description
The measurement of the ability of URB602 compound to inhibit MGL activity.


Chem Biol 14: 1357-65 (2007)


Article DOI: 10.1016/j.chembiol.2007.10.017
BindingDB Entry DOI: 10.7270/Q2XS5SW0
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM81321
PNG
(URB602, 3m)
Show SMILES Cc1cccc(c1)-c1cccc(NC(=O)OC(CO)CO)c1
Show InChI InChI=1S/C17H19NO4/c1-12-4-2-5-13(8-12)14-6-3-7-15(9-14)18-17(21)22-16(10-19)11-20/h2-9,16,19-20H,10-11H2,1H3,(H,18,21)
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n/an/a>3.00E+5n/an/an/an/a8.0n/a



University of California, Irvine



Assay Description
The measurement of the ability of URB602 compound to inhibit MGL activity.


Chem Biol 14: 1357-65 (2007)


Article DOI: 10.1016/j.chembiol.2007.10.017
BindingDB Entry DOI: 10.7270/Q2XS5SW0
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM81322
PNG
(URB602, 3n)
Show SMILES OCC(CO)OC(=O)Nc1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C16H17NO4/c18-10-15(11-19)21-16(20)17-14-8-4-7-13(9-14)12-5-2-1-3-6-12/h1-9,15,18-19H,10-11H2,(H,17,20)
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n/an/a>3.00E+5n/an/an/an/a8.0n/a



University of California, Irvine



Assay Description
The measurement of the ability of URB602 compound to inhibit MGL activity.


Chem Biol 14: 1357-65 (2007)


Article DOI: 10.1016/j.chembiol.2007.10.017
BindingDB Entry DOI: 10.7270/Q2XS5SW0
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM81323
PNG
(URB602, 3o)
Show SMILES CN(C(=O)OC1CCCCC1)c1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C20H23NO2/c1-21(20(22)23-19-13-6-3-7-14-19)18-12-8-11-17(15-18)16-9-4-2-5-10-16/h2,4-5,8-12,15,19H,3,6-7,13-14H2,1H3
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n/an/a>3.00E+5n/an/an/an/a8.0n/a



University of California, Irvine



Assay Description
The measurement of the ability of URB602 compound to inhibit MGL activity.


Chem Biol 14: 1357-65 (2007)


Article DOI: 10.1016/j.chembiol.2007.10.017
BindingDB Entry DOI: 10.7270/Q2XS5SW0
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM81324
PNG
(URB602, 4a)
Show SMILES O=C(NC1CCCCC1)Nc1cccc(c1)-c1ccccc1
Show InChI InChI=1S/C19H22N2O/c22-19(20-17-11-5-2-6-12-17)21-18-13-7-10-16(14-18)15-8-3-1-4-9-15/h1,3-4,7-10,13-14,17H,2,5-6,11-12H2,(H2,20,21,22)
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n/an/a 1.15E+5n/an/an/an/a8.0n/a



University of California, Irvine



Assay Description
The measurement of the ability of URB602 compound to inhibit MGL activity.


Chem Biol 14: 1357-65 (2007)


Article DOI: 10.1016/j.chembiol.2007.10.017
BindingDB Entry DOI: 10.7270/Q2XS5SW0
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM50274152
PNG
((2S,9Z)-octadec-9-ene-1,2-diamine dihydrochloride ...)
Show SMILES CCCCCCCC\C=C/CCCCCC[C@H](N)CN
Show InChI InChI=1S/C18H38N2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18(20)17-19/h9-10,18H,2-8,11-17,19-20H2,1H3/b10-9-/t18-/m0/s1
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2.18E+4n/an/an/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Inhibition of Sprague-Dawley rat MGL


Bioorg Med Chem Lett 18: 5424-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.09.039
BindingDB Entry DOI: 10.7270/Q2VM4C30
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM50274153
PNG
((2R,9Z)-octadec-9-ene-1,2-diamine dihydrochloride ...)
Show SMILES CCCCCCCC\C=C/CCCCCC[C@@H](N)CN
Show InChI InChI=1S/C18H38N2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-18(20)17-19/h9-10,18H,2-8,11-17,19-20H2,1H3/b10-9-/t18-/m1/s1
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3.90E+4n/an/an/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Inhibition of Sprague-Dawley rat MGL


Bioorg Med Chem Lett 18: 5424-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.09.039
BindingDB Entry DOI: 10.7270/Q2VM4C30
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM50274151
PNG
(CHEMBL473249 | hexadecane-1,2-diamine dihydrochlor...)
Show SMILES CCCCCCCCCCCCCCC(N)CN
Show InChI InChI=1S/C16H36N2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-16(18)15-17/h16H,2-15,17-18H2,1H3
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5.87E+4n/an/an/an/an/an/an/an/a



University of Athens

Curated by ChEMBL


Assay Description
Inhibition of Sprague-Dawley rat MGL


Bioorg Med Chem Lett 18: 5424-7 (2008)


Article DOI: 10.1016/j.bmcl.2008.09.039
BindingDB Entry DOI: 10.7270/Q2VM4C30
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM81363
PNG
(Pristimerin)
Show SMILES COC(=O)[C@]1(C)CC[C@]2(C)CC[C@]3(C)C4=CC=c5c(cc(O)c(O)c5=C)[C@]4(C)CC[C@@]3(C)C2C1
Show InChI InChI=1S/C30H40O4/c1-18-19-8-9-22-28(4,20(19)16-21(31)24(18)32)13-15-30(6)23-17-27(3,25(33)34-7)11-10-26(23,2)12-14-29(22,30)5/h8-9,16,23,31-32H,1,10-15,17H2,2-7H3/t23?,26-,27-,28+,29-,30+/m1/s1
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n/an/a 93n/an/an/an/an/a37



University of California Irvine



Assay Description
Purified recombinant rat MGL was prepared and enzyme activity was assayed.


Chem Biol 16: 1045-52 (2009)


Article DOI: 10.1016/j.chembiol.2009.09.012
BindingDB Entry DOI: 10.7270/Q2HH6HJ3
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM50071058
PNG
((2R,4aS,6aS,12bR,14aS,14bR)-10-Hydroxy-2,4a,6a,9,1...)
Show SMILES C[C@]12CC[C@](C)(C[C@H]1[C@]1(C)CC[C@]3(C)C(=CC=c4c3cc(O)c(O)c4=C)[C@@]1(C)CC2)C(O)=O
Show InChI InChI=1S/C29H38O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h7-8,15,22,30-31H,1,9-14,16H2,2-6H3,(H,32,33)/t22-,25-,26-,27+,28-,29+/m1/s1
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n/an/a 1.60E+3n/an/an/an/an/a37



University of California Irvine



Assay Description
Purified recombinant rat MGL was prepared and enzyme activity was assayed.


Chem Biol 16: 1045-52 (2009)


Article DOI: 10.1016/j.chembiol.2009.09.012
BindingDB Entry DOI: 10.7270/Q2HH6HJ3
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM81364
PNG
(Pristimerol)
Show SMILES COC(=O)[C@]1(C)CC[C@]2(C)CC[C@]3(C)C4=CCc5c(C)c(O)c(O)cc5[C@]4(C)CC[C@@]3(C)C2C1
Show InChI InChI=1S/C30H42O4/c1-18-19-8-9-22-28(4,20(19)16-21(31)24(18)32)13-15-30(6)23-17-27(3,25(33)34-7)11-10-26(23,2)12-14-29(22,30)5/h9,16,23,31-32H,8,10-15,17H2,1-7H3/t23?,26-,27-,28+,29-,30+/m1/s1
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n/an/a 4.00E+3n/an/an/an/an/a37



University of California Irvine



Assay Description
Purified recombinant rat MGL was prepared and enzyme activity was assayed.


Chem Biol 16: 1045-52 (2009)


Article DOI: 10.1016/j.chembiol.2009.09.012
BindingDB Entry DOI: 10.7270/Q2HH6HJ3
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM81365
PNG
(Dihydrocelastrol)
Show SMILES Cc1c(O)c(O)cc2c1CC=C1[C@@]2(C)CC[C@@]2(C)C3C[C@@](C)(CC[C@]3(C)CC[C@]12C)C(O)=O
Show InChI InChI=1S/C29H40O4/c1-17-18-7-8-21-27(4,19(18)15-20(30)23(17)31)12-14-29(6)22-16-26(3,24(32)33)10-9-25(22,2)11-13-28(21,29)5/h8,15,22,30-31H,7,9-14,16H2,1-6H3,(H,32,33)/t22?,25-,26-,27+,28-,29+/m1/s1
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n/an/a 1.50E+4n/an/an/an/an/a37



University of California Irvine



Assay Description
Purified recombinant rat MGL was prepared and enzyme activity was assayed.


Chem Biol 16: 1045-52 (2009)


Article DOI: 10.1016/j.chembiol.2009.09.012
BindingDB Entry DOI: 10.7270/Q2HH6HJ3
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM81366
PNG
(Dihydrocelastryl diacetate)
Show SMILES CC(=O)Oc1cc2c(CC=C3[C@@]2(C)CC[C@@]2(C)[C@@H]4C[C@@](C)(CC[C@]4(C)CC[C@]32C)C(O)=O)c(C)c1OC(C)=O
Show InChI InChI=1S/C33H44O6/c1-19-22-9-10-25-31(6,23(22)17-24(38-20(2)34)27(19)39-21(3)35)14-16-33(8)26-18-30(5,28(36)37)12-11-29(26,4)13-15-32(25,33)7/h10,17,26H,9,11-16,18H2,1-8H3,(H,36,37)/t26-,29-,30-,31+,32-,33+/m1/s1
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n/an/a 1.50E+4n/an/an/an/an/a37



University of California Irvine



Assay Description
Purified recombinant rat MGL was prepared and enzyme activity was assayed.


Chem Biol 16: 1045-52 (2009)


Article DOI: 10.1016/j.chembiol.2009.09.012
BindingDB Entry DOI: 10.7270/Q2HH6HJ3
More data for this
Ligand-Target Pair
Monoglyceride Lipase (MGL)


(Mus musculus (mouse))
BDBM50012157
PNG
(CHEMBL3264462)
Show SMILES O=C(C1CCc2cc(Oc3ccccc3)ccc2O1)c1ncc(o1)-c1ccccn1
Show InChI InChI=1S/C24H18N2O4/c27-23(24-26-15-22(30-24)19-8-4-5-13-25-19)21-11-9-16-14-18(10-12-20(16)29-21)28-17-6-2-1-3-7-17/h1-8,10,12-15,21H,9,11H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of mouse brain MAGL incubated for 10 mins prior to rhodamine-tagged fluorophosphonate addition measured after 10 mins by SDS-PAGE


Bioorg Med Chem 22: 2763-70 (2014)


Article DOI: 10.1016/j.bmc.2014.03.013
BindingDB Entry DOI: 10.7270/Q2X92CVM
More data for this
Ligand-Target Pair
Monoglyceride Lipase (MGL)


(Mus musculus (mouse))
BDBM50012157
PNG
(CHEMBL3264462)
Show SMILES O=C(C1CCc2cc(Oc3ccccc3)ccc2O1)c1ncc(o1)-c1ccccn1
Show InChI InChI=1S/C24H18N2O4/c27-23(24-26-15-22(30-24)19-8-4-5-13-25-19)21-11-9-16-14-18(10-12-20(16)29-21)28-17-6-2-1-3-7-17/h1-8,10,12-15,21H,9,11H2
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n/an/a>1.00E+5n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of mouse brain MAGL incubated for 10 mins prior to rhodamine-tagged fluorophosphonate addition measured after 10 mins by SDS-PAGE


Bioorg Med Chem 22: 2763-70 (2014)


Article DOI: 10.1016/j.bmc.2014.03.013
BindingDB Entry DOI: 10.7270/Q2X92CVM
More data for this
Ligand-Target Pair
Monoglyceride Lipase (MGL)


(Mus musculus (mouse))
BDBM50012169
PNG
(CHEMBL3264473)
Show SMILES O=C([C@H]1COc2cc(Oc3ccccc3)ccc2C1)c1ncc(o1)-c1ccccn1
Show InChI InChI=1S/C24H18N2O4/c27-23(24-26-14-22(30-24)20-8-4-5-11-25-20)17-12-16-9-10-19(13-21(16)28-15-17)29-18-6-2-1-3-7-18/h1-11,13-14,17H,12,15H2/t17-/m1/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of mouse brain MAGL incubated for 10 mins prior to rhodamine-tagged fluorophosphonate addition measured after 10 mins by SDS-PAGE


Bioorg Med Chem 22: 2763-70 (2014)


Article DOI: 10.1016/j.bmc.2014.03.013
BindingDB Entry DOI: 10.7270/Q2X92CVM
More data for this
Ligand-Target Pair
Monoglyceride Lipase (MGL)


(Mus musculus (mouse))
BDBM50012171
PNG
(CHEMBL3264474)
Show SMILES O=C([C@@H]1COc2cc(Oc3ccccc3)ccc2C1)c1ncc(o1)-c1ccccn1
Show InChI InChI=1S/C24H18N2O4/c27-23(24-26-14-22(30-24)20-8-4-5-11-25-20)17-12-16-9-10-19(13-21(16)28-15-17)29-18-6-2-1-3-7-18/h1-11,13-14,17H,12,15H2/t17-/m0/s1
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n/an/a>1.00E+5n/an/an/an/an/an/a



The Scripps Research Institute

Curated by ChEMBL


Assay Description
Inhibition of mouse brain MAGL incubated for 10 mins prior to rhodamine-tagged fluorophosphonate addition measured after 10 mins by SDS-PAGE


Bioorg Med Chem 22: 2763-70 (2014)


Article DOI: 10.1016/j.bmc.2014.03.013
BindingDB Entry DOI: 10.7270/Q2X92CVM
More data for this
Ligand-Target Pair
Monoglyceride Lipase (MGL)


(Mus musculus (mouse))
BDBM50438783
PNG
(CHEMBL2415106)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)NCc1ccccc1
Show InChI InChI=1S/C25H39NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-25(27)26-23-24-20-17-16-18-21-24/h6-7,9-10,16-18,20-21H,2-5,8,11-15,19,22-23H2,1H3,(H,26,27)/b7-6-,10-9-
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n/an/a>1.00E+5n/an/an/an/an/an/a



University of Szeged

Curated by ChEMBL


Assay Description
Inhibition of mouse brain MAGL-mediated [glycerol-1,2,3-3H]-2-OG hydrolysis preincubated for 15 mins measured 15 mins post 2-OG addition by liquid sc...


J Nat Prod 77: 1663-9 (2014)


Article DOI: 10.1021/np500292g
BindingDB Entry DOI: 10.7270/Q269757F
More data for this
Ligand-Target Pair
Monoglyceride Lipase (MGL)


(Mus musculus (mouse))
BDBM50438779
PNG
(CHEMBL2413161)
Show SMILES CC\C=C/C\C=C/C\C=C/CCCCCCCC(=O)NCc1ccccc1
Show InChI InChI=1S/C25H37NO/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-19-22-25(27)26-23-24-20-17-16-18-21-24/h3-4,6-7,9-10,16-18,20-21H,2,5,8,11-15,19,22-23H2,1H3,(H,26,27)/b4-3-,7-6-,10-9-
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n/an/a>1.00E+5n/an/an/an/an/an/a



University of Szeged

Curated by ChEMBL


Assay Description
Inhibition of mouse brain MAGL-mediated [glycerol-1,2,3-3H]-2-OG hydrolysis preincubated for 15 mins measured 15 mins post 2-OG addition by liquid sc...


J Nat Prod 77: 1663-9 (2014)


Article DOI: 10.1021/np500292g
BindingDB Entry DOI: 10.7270/Q269757F
More data for this
Ligand-Target Pair
Monoglyceride Lipase (MGL)


(Mus musculus (mouse))
BDBM50438782
PNG
(CHEMBL2413162)
Show SMILES CC\C=C/C\C=C/C\C=C/CCCCCCCC(=O)NCc1cccc(OC)c1
Show InChI InChI=1S/C26H39NO2/c1-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21-26(28)27-23-24-19-18-20-25(22-24)29-2/h4-5,7-8,10-11,18-20,22H,3,6,9,12-17,21,23H2,1-2H3,(H,27,28)/b5-4-,8-7-,11-10-
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n/an/a>1.00E+5n/an/an/an/an/an/a



University of Szeged

Curated by ChEMBL


Assay Description
Inhibition of mouse brain MAGL-mediated [glycerol-1,2,3-3H]-2-OG hydrolysis preincubated for 15 mins measured 15 mins post 2-OG addition by liquid sc...


J Nat Prod 77: 1663-9 (2014)


Article DOI: 10.1021/np500292g
BindingDB Entry DOI: 10.7270/Q269757F
More data for this
Ligand-Target Pair
Monoglyceride Lipase (MGL)


(Mus musculus (mouse))
BDBM50048063
PNG
(CHEMBL3314943)
Show SMILES CCC\C=C\C\C=C\CCC\C=C\C=C\C(=O)NCC(C)CC
Show InChI InChI=1S/C21H35NO/c1-4-6-7-8-9-10-11-12-13-14-15-16-17-18-21(23)22-19-20(3)5-2/h7-8,10-11,15-18,20H,4-6,9,12-14,19H2,1-3H3,(H,22,23)/b8-7+,11-10+,16-15+,18-17+
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n/an/a>1.00E+5n/an/an/an/an/an/a



University of Szeged

Curated by ChEMBL


Assay Description
Inhibition of mouse brain MAGL-mediated [glycerol-1,2,3-3H]-2-OG hydrolysis preincubated for 15 mins measured 15 mins post 2-OG addition by liquid sc...


J Nat Prod 77: 1663-9 (2014)


Article DOI: 10.1021/np500292g
BindingDB Entry DOI: 10.7270/Q269757F
More data for this
Ligand-Target Pair
Monoglyceride Lipase (MGL)


(Mus musculus (mouse))
BDBM50048064
PNG
(CHEMBL3314942)
Show SMILES CC#CC#CC\C=C/CCC\C=C\C=C\C(=O)NCC(C)C
Show InChI InChI=1S/C20H27NO/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-20(22)21-18-19(2)3/h9-10,14-17,19H,8,11-13,18H2,1-3H3,(H,21,22)/b10-9-,15-14+,17-16+
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n/an/a>1.00E+5n/an/an/an/an/an/a



University of Szeged

Curated by ChEMBL


Assay Description
Inhibition of mouse brain MAGL-mediated [glycerol-1,2,3-3H]-2-OG hydrolysis preincubated for 15 mins measured 15 mins post 2-OG addition by liquid sc...


J Nat Prod 77: 1663-9 (2014)


Article DOI: 10.1021/np500292g
BindingDB Entry DOI: 10.7270/Q269757F
More data for this
Ligand-Target Pair
Monoglyceride Lipase (MGL)


(Mus musculus (mouse))
BDBM50048065
PNG
(CHEMBL3314941)
Show SMILES CCC\C=C/C#C\C=C/C=C/CC\C=C\C=C\C(=O)NCC(C)C
Show InChI InChI=1S/C22H31NO/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-22(24)23-20-21(2)3/h6-7,10-13,16-19,21H,4-5,14-15,20H2,1-3H3,(H,23,24)/b7-6-,11-10-,13-12+,17-16+,19-18+
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n/an/a>1.00E+5n/an/an/an/an/an/a



University of Szeged

Curated by ChEMBL


Assay Description
Inhibition of mouse brain MAGL-mediated [glycerol-1,2,3-3H]-2-OG hydrolysis preincubated for 15 mins measured 15 mins post 2-OG addition by liquid sc...


J Nat Prod 77: 1663-9 (2014)


Article DOI: 10.1021/np500292g
BindingDB Entry DOI: 10.7270/Q269757F
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM50191457
PNG
(4-(thiazol-2-yl)phenyl butylcarbamate | CHEMBL3767...)
Show SMILES CCCCNC(=O)Oc1ccc(cc1)-c1nccs1
Show InChI InChI=1S/C14H16N2O2S/c1-2-3-8-16-14(17)18-12-6-4-11(5-7-12)13-15-9-10-19-13/h4-7,9-10H,2-3,8H2,1H3,(H,16,17)
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n/an/a 3.10E+4n/an/an/an/an/an/a



University of Kuopio

Curated by ChEMBL


Assay Description
Inhibition of MGL-like activity in Wistar rat cerebellar membranes


J Med Chem 49: 4650-6 (2006)


Article DOI: 10.1021/jm060394q
BindingDB Entry DOI: 10.7270/Q2Q52P8G
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM50220342
PNG
(CHEMBL230760 | tetrahydro-2H-pyran-4-yl (5Z,8Z,11Z...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC1CCOCC1
Show InChI InChI=1S/C25H40O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-25(26)28-24-20-22-27-23-21-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-23H2,1H3/b7-6-,10-9-,13-12-,16-15-
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n/an/a 3.00E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis


J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM50107601
PNG
((5Z,8Z,11Z,14Z)-Icosa-5,8,11,14-tetraenoic acid (t...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)NCC1CCCO1
Show InChI InChI=1S/C25H41NO2/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-21-25(27)26-23-24-20-19-22-28-24/h6-7,9-10,12-13,15-16,24H,2-5,8,11,14,17-23H2,1H3,(H,26,27)/b7-6-,10-9-,13-12-,16-15-
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n/an/a 3.40E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis


J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM50220345
PNG
((+/-)-oxiran-2-ylmethyl (9Z,12Z,15Z)-octadeca-9,12...)
Show SMILES CC\C=C/C\C=C/C\C=C/CCCCCCCC(=O)OCC1CO1
Show InChI InChI=1S/C21H34O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(22)24-19-20-18-23-20/h3-4,6-7,9-10,20H,2,5,8,11-19H2,1H3/b4-3-,7-6-,10-9-
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n/an/a 5.00E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum membrane fractions assessed as [3H]-2-oleoglycerol hydrolysis


J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM50220347
PNG
((+/-)-oxiran-2-ylmethyl (5Z,8Z,11Z,14Z)-icosa-5,8,...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC1CO1
Show InChI InChI=1S/C23H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(24)26-21-22-20-25-22/h6-7,9-10,12-13,15-16,22H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-
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n/an/a 4.50E+3n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis


J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM50220348
PNG
((+/-)-2,2-Dimethyl-1,3-dioxolan-4-ylmethyl (5Z,8Z,...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC1COC(C)(C)O1
Show InChI InChI=1S/C26H42O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-25(27)28-22-24-23-29-26(2,3)30-24/h8-9,11-12,14-15,17-18,24H,4-7,10,13,16,19-23H2,1-3H3/b9-8-,12-11-,15-14-,18-17-
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n/an/a 4.50E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis


J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM50220345
PNG
((+/-)-oxiran-2-ylmethyl (9Z,12Z,15Z)-octadeca-9,12...)
Show SMILES CC\C=C/C\C=C/C\C=C/CCCCCCCC(=O)OCC1CO1
Show InChI InChI=1S/C21H34O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-21(22)24-19-20-18-23-20/h3-4,6-7,9-10,20H,2,5,8,11-19H2,1H3/b4-3-,7-6-,10-9-
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n/an/a 1.10E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis


J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM50220347
PNG
((+/-)-oxiran-2-ylmethyl (5Z,8Z,11Z,14Z)-icosa-5,8,...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCC1CO1
Show InChI InChI=1S/C23H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(24)26-21-22-20-25-22/h6-7,9-10,12-13,15-16,22H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-
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n/an/a 1.90E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum membrane fractions assessed as [3H]-2-oleoglycerol hydrolysis


J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM50220350
PNG
(1,3-benzodioxol-5-ylmethyl (5Z,8Z,11Z,14Z)-icosa-5...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCc1ccc2OCOc2c1
Show InChI InChI=1S/C28H38O4/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-28(29)30-23-25-20-21-26-27(22-25)32-24-31-26/h6-7,9-10,12-13,15-16,20-22H,2-5,8,11,14,17-19,23-24H2,1H3/b7-6-,10-9-,13-12-,16-15-
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n/an/a 4.50E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis


J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM50220349
PNG
((S,5Z,8Z,11Z,14Z)-oxiran-2-ylmethyl icosa-5,8,11,1...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OC[C@@H]1CO1
Show InChI InChI=1S/C23H36O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-23(24)26-21-22-20-25-22/h6-7,9-10,12-13,15-16,22H,2-5,8,11,14,17-21H2,1H3/b7-6-,10-9-,13-12-,16-15-/t22-/m0/s1
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n/an/a 8.00E+3n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis


J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM50220343
PNG
((+/-)-tetrahydro-2H-pyran-2-ylmethyl (9Z,12Z)-octa...)
Show SMILES CCCCC\C=C/C\C=C/CCCCCCCC(=O)OCC1CCCCO1
Show InChI InChI=1S/C24H42O3/c1-2-3-4-5-6-7-8-9-10-11-12-13-14-15-16-20-24(25)27-22-23-19-17-18-21-26-23/h6-7,9-10,23H,2-5,8,11-22H2,1H3/b7-6-,10-9-
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n/an/a 7.30E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis


J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
Monoglyceride lipase (MGL)


(Rattus norvegicus (Rat))
BDBM50220344
PNG
(2-(5,5-dimethyl-1,3-dioxan-2-yl)ethyl (5Z,8Z,11Z,1...)
Show SMILES CCCCC\C=C/C\C=C/C\C=C/C\C=C/CCCC(=O)OCCC1OCC(C)(C)CO1
Show InChI InChI=1S/C28H46O4/c1-4-5-6-7-8-9-10-11-12-13-14-15-16-17-18-19-20-21-26(29)30-23-22-27-31-24-28(2,3)25-32-27/h8-9,11-12,14-15,17-18,27H,4-7,10,13,16,19-25H2,1-3H3/b9-8-,12-11-,15-14-,18-17-
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n/an/a 2.70E+4n/an/an/an/an/an/a



Universidad Complutense

Curated by ChEMBL


Assay Description
Inhibition of MGL in rat cerebellum cytosolic fractions assessed as [3H]-2-oleoglycerol hydrolysis


J Med Chem 50: 5012-23 (2007)


Article DOI: 10.1021/jm070642y
BindingDB Entry DOI: 10.7270/Q2N879HC
More data for this
Ligand-Target Pair
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