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Found 218 hits Enz. Inhib. hit(s) with Target = 'N-acylethanolamine-hydrolyzing acid amidase (NAAA)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50389007
PNG
(CHEMBL1214255 | US9321743, SD41)
Show SMILES O=C(N[C@H]1COC1=O)OCc1ccccc1
Show InChI InChI=1S/C11H11NO4/c13-10-9(7-15-10)12-11(14)16-6-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,12,14)/t9-/m0/s1
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n/an/a 2.96E+3n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50416518
PNG
(CHEMBL1214332 | US9321743, URB867)
Show SMILES O=C(Cc1ccccc1)N[C@H]1COC1=O
Show InChI InChI=1S/C11H11NO3/c13-10(12-9-7-15-11(9)14)6-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,12,13)/t9-/m0/s1
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n/an/a 1.85E+3n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM223535
PNG
(US9321743, URB788)
Show SMILES O=C(N[C@H]1CNC1=O)OCc1ccccc1
Show InChI InChI=1S/C11H12N2O3/c14-10-9(6-12-10)13-11(15)16-7-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,12,14)(H,13,15)/t9-/m0/s1
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n/an/a 1.60E+4n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50389010
PNG
(CHEMBL245258 | US9321743, Cbz-D-Ser)
Show SMILES OC[C@@H](NC(=O)OCc1ccccc1)C(O)=O
Show InChI InChI=1S/C11H13NO5/c13-6-9(10(14)15)12-11(16)17-7-8-4-2-1-3-5-8/h1-5,9,13H,6-7H2,(H,12,16)(H,14,15)/t9-/m1/s1
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n/an/a>1.00E+5n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50389012
PNG
(CHEMBL2064169 | US9321743, URB786)
Show SMILES O=C(NC1CCC1=O)OCc1ccccc1
Show InChI InChI=1S/C12H13NO3/c14-11-7-6-10(11)13-12(15)16-8-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H,13,15)
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n/an/a>1.00E+5n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM223536
PNG
(US9321743, Cbz-D-Ala)
Show SMILES C[C@@H](NC(=O)OCc1ccccc1)C(O)=O
Show InChI InChI=1S/C11H13NO4/c1-8(10(13)14)12-11(15)16-7-9-5-3-2-4-6-9/h2-6,8H,7H2,1H3,(H,12,15)(H,13,14)/t8-/m1/s1
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n/an/a>1.00E+5n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50389009
PNG
(CHEMBL1222399 | US9321743, Cbz-L-Ser)
Show SMILES OC[C@H](NC(=O)OCc1ccccc1)C(O)=O
Show InChI InChI=1S/C11H13NO5/c13-6-9(10(14)15)12-11(16)17-7-8-4-2-1-3-5-8/h1-5,9,13H,6-7H2,(H,12,16)(H,14,15)/t9-/m0/s1
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n/an/a>1.00E+5n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM223537
PNG
(US9321743, Cbz-gly)
Show SMILES OC(=O)CNC(=O)OCc1ccccc1
Show InChI InChI=1S/C10H11NO4/c12-9(13)6-11-10(14)15-7-8-4-2-1-3-5-8/h1-5H,6-7H2,(H,11,14)(H,12,13)
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n/an/a>1.00E+5n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM223538
PNG
(US9321743, Cbz-L-Ala)
Show SMILES C[C@H](NC(=O)OCc1ccccc1)C(O)=O
Show InChI InChI=1S/C11H13NO4/c1-8(10(13)14)12-11(15)16-7-9-5-3-2-4-6-9/h2-6,8H,7H2,1H3,(H,12,15)(H,13,14)/t8-/m0/s1
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n/an/a>1.00E+5n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50389011
PNG
(CHEMBL2064168 | US9321743, URB787)
Show SMILES O=C(NC1CCC1)OCc1ccccc1
Show InChI InChI=1S/C12H15NO2/c14-12(13-11-7-4-8-11)15-9-10-5-2-1-3-6-10/h1-3,5-6,11H,4,7-9H2,(H,13,14)
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n/an/a>1.00E+5n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50416509
PNG
(CHEMBL1214256 | US9321743, URB783)
Show SMILES O=C(CCc1ccccc1)N[C@H]1COC1=O
Show InChI InChI=1S/C12H13NO3/c14-11(13-10-8-16-12(10)15)7-6-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H,13,14)/t10-/m0/s1
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n/an/a 420n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50416510
PNG
(CHEMBL1214257 | US9321743, URB818)
Show SMILES O=C(CCc1ccccc1)N[C@@H]1COC1=O
Show InChI InChI=1S/C12H13NO3/c14-11(13-10-8-16-12(10)15)7-6-9-4-2-1-3-5-9/h1-5,10H,6-8H2,(H,13,14)/t10-/m1/s1
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n/an/a 6.00E+3n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50416515
PNG
(CHEMBL1214329 | US9321743, URB820)
Show SMILES C[C@H]1OC(=O)[C@H]1NC(=O)CCc1ccccc1
Show InChI InChI=1S/C13H15NO3/c1-9-12(13(16)17-9)14-11(15)8-7-10-5-3-2-4-6-10/h2-6,9,12H,7-8H2,1H3,(H,14,15)/t9-,12+/m1/s1
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n/an/a 1.00E+5n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50416516
PNG
(CHEMBL1214330 | US9321743, URB819)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)CCc1ccccc1
Show InChI InChI=1S/C13H15NO3/c1-9-12(13(16)17-9)14-11(15)8-7-10-5-3-2-4-6-10/h2-6,9,12H,7-8H2,1H3,(H,14,15)/t9-,12+/m0/s1
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n/an/a 3.20E+3n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM223539
PNG
(US9321743, URB868)
Show SMILES O=C(CCc1ccccc1)N[C@H]1CCC1=O
Show InChI InChI=1S/C13H15NO2/c15-12-8-7-11(12)14-13(16)9-6-10-4-2-1-3-5-10/h1-5,11H,6-9H2,(H,14,16)/t11-/m0/s1
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n/an/a>1.00E+5n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM223540
PNG
(US9321743, URB822)
Show SMILES O=C1OC[C@H]1NCCCc1ccccc1
Show InChI InChI=1S/C12H15NO2/c14-12-11(9-15-12)13-8-4-7-10-5-2-1-3-6-10/h1-3,5-6,11,13H,4,7-9H2/t11-/m1/s1
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n/an/a>1.00E+5n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50416513
PNG
(CHEMBL1214327 | US9321743, URB828)
Show SMILES O=C(CCc1ccccc1)NC1CCC1
Show InChI InChI=1S/C13H17NO/c15-13(14-12-7-4-8-12)10-9-11-5-2-1-3-6-11/h1-3,5-6,12H,4,7-10H2,(H,14,15)
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n/an/a>1.00E+5n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50389016
PNG
(CHEMBL2064173 | US9321743, URB863)
Show SMILES O=C(NCc1ccccc1)N[C@@H]1COC1=O
Show InChI InChI=1S/C11H12N2O3/c14-10-9(7-16-10)13-11(15)12-6-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H2,12,13,15)/t9-/m1/s1
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n/an/a 4.92E+4n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50416511
PNG
(CHEMBL1214258 | US9321743, URB827)
Show SMILES OC[C@H](NC(=O)CCc1ccccc1)C(O)=O
Show InChI InChI=1S/C12H15NO4/c14-8-10(12(16)17)13-11(15)7-6-9-4-2-1-3-5-9/h1-5,10,14H,6-8H2,(H,13,15)(H,16,17)/t10-/m0/s1
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n/an/a>1.00E+5n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50389015
PNG
(CHEMBL2064172 | US9321743, URB784)
Show SMILES O=C(NCc1ccccc1)N[C@H]1COC1=O
Show InChI InChI=1S/C11H12N2O3/c14-10-9(7-16-10)13-11(15)12-6-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H2,12,13,15)/t9-/m0/s1
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n/an/a 1.50E+4n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50416517
PNG
(CHEMBL1214331 | US9321743, URB821)
Show SMILES O=C1OCC1CCCCc1ccccc1
Show InChI InChI=1S/C13H16O2/c14-13-12(10-15-13)9-5-4-8-11-6-2-1-3-7-11/h1-3,6-7,12H,4-5,8-10H2
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US Patent
n/an/a 1.10E+4n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50416520
PNG
(CHEMBL1214386 | US9321743, URB864)
Show SMILES CCCCCCC(=O)N[C@H]1COC1=O
Show InChI InChI=1S/C10H17NO3/c1-2-3-4-5-6-9(12)11-8-7-14-10(8)13/h8H,2-7H2,1H3,(H,11,12)/t8-/m0/s1
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n/an/a 460n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50416519
PNG
(CHEMBL1214333 | US9321743, URB865)
Show SMILES O=C(CCCCCCc1ccccc1)N[C@H]1COC1=O
Show InChI InChI=1S/C16H21NO3/c18-15(17-14-12-20-16(14)19)11-7-2-1-4-8-13-9-5-3-6-10-13/h3,5-6,9-10,14H,1-2,4,7-8,11-12H2,(H,17,18)/t14-/m0/s1
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n/an/a 1.50E+3n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50416524
PNG
(CHEMBL1214390 | US9321743, URB866)
Show SMILES O=C(N[C@H]1COC1=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C14H11NO3/c16-13(15-12-8-18-14(12)17)11-6-5-9-3-1-2-4-10(9)7-11/h1-7,12H,8H2,(H,15,16)/t12-/m0/s1
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n/an/a 1.60E+3n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50389008
PNG
(CHEMBL2064167 | US9321743, URB785)
Show SMILES O=C(N[C@@H]1COC1=O)OCc1ccccc1
Show InChI InChI=1S/C11H11NO4/c13-10-9(7-15-10)12-11(14)16-6-8-4-2-1-3-5-8/h1-5,9H,6-7H2,(H,12,14)/t9-/m1/s1
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n/an/a 700n/an/an/an/a5.037



The Regents of the University of California; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Recombinant NAAA or native rat lung NAAA was incubated at 37 °C. for 30 min in 0.2 ml of sodium hydrogen phosphate buffer (50 mM, pH 5.0) contain...


US Patent US9321743 (2016)


BindingDB Entry DOI: 10.7270/Q26D5RVT
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50032454
PNG
(CHEMBL3354147 | US9353075, 44)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCc1ccc(cc1)-c1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C19H16F3NO4/c1-11-16(17(24)27-11)23-18(25)26-10-12-2-4-13(5-3-12)14-6-8-15(9-7-14)19(20,21)22/h2-9,11,16H,10H2,1H3,(H,23,25)/t11-,16+/m0/s1
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n/an/a 24n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50032457
PNG
(CHEMBL3354143 | US9353075, 45)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCc1ccc(cc1)-c1ccsc1
Show InChI InChI=1S/C16H15NO4S/c1-10-14(15(18)21-10)17-16(19)20-8-11-2-4-12(5-3-11)13-6-7-22-9-13/h2-7,9-10,14H,8H2,1H3,(H,17,19)/t10-,14+/m0/s1
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n/an/a 21n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50032453
PNG
(CHEMBL3354148 | US9353075, 46)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCc1ccc(OC2CCCCC2)cc1
Show InChI InChI=1S/C18H23NO5/c1-12-16(17(20)23-12)19-18(21)22-11-13-7-9-15(10-8-13)24-14-5-3-2-4-6-14/h7-10,12,14,16H,2-6,11H2,1H3,(H,19,21)/t12-,16+/m0/s1
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n/an/a 23n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50439659
PNG
(CHEMBL2419824 | US9353075, 1)
Show SMILES CCCCCOC(=O)N[C@@H]1[C@H](C)OC1=O
Show InChI InChI=1S/C10H17NO4/c1-3-4-5-6-14-10(13)11-8-7(2)15-9(8)12/h7-8H,3-6H2,1-2H3,(H,11,13)/t7-,8+/m0/s1
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n/an/a 670n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50439656
PNG
(CHEMBL2419827 | US9353075, 2)
Show SMILES CCCCCCCCOC(=O)N[C@@H]1[C@H](C)OC1=O
Show InChI InChI=1S/C13H23NO4/c1-3-4-5-6-7-8-9-17-13(16)14-11-10(2)18-12(11)15/h10-11H,3-9H2,1-2H3,(H,14,16)/t10-,11+/m0/s1
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n/an/a 30n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50032460
PNG
(CHEMBL3353550 | US9353075, 3)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCc1ccc(C)cc1
Show InChI InChI=1S/C14H17NO4/c1-9-3-5-11(6-4-9)7-8-18-14(17)15-12-10(2)19-13(12)16/h3-6,10,12H,7-8H2,1-2H3,(H,15,17)/t10-,12+/m0/s1
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n/an/a 1.21E+3n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50439662
PNG
(CHEMBL2419821 | US9353075, 4)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCc1ccccc1
Show InChI InChI=1S/C14H17NO4/c1-10-12(13(16)19-10)15-14(17)18-9-5-8-11-6-3-2-4-7-11/h2-4,6-7,10,12H,5,8-9H2,1H3,(H,15,17)/t10-,12+/m0/s1
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n/an/a 84n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50439661
PNG
(CHEMBL2419822 | US9353075, 5)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCCc1ccccc1
Show InChI InChI=1S/C15H19NO4/c1-11-13(14(17)20-11)16-15(18)19-10-6-5-9-12-7-3-2-4-8-12/h2-4,7-8,11,13H,5-6,9-10H2,1H3,(H,16,18)/t11-,13+/m0/s1
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n/an/a 390n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50389023
PNG
(CHEMBL2064166 | US9353075, 6)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCCCc1ccccc1
Show InChI InChI=1S/C16H21NO4/c1-12-14(15(18)21-12)17-16(19)20-11-7-3-6-10-13-8-4-2-5-9-13/h2,4-5,8-9,12,14H,3,6-7,10-11H2,1H3,(H,17,19)/t12-,14+/m0/s1
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n/an/a 50n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50439649
PNG
(CHEMBL2419811 | US9353075, 7)
Show SMILES CCCCCCC[C@H](C)OC(=O)N[C@@H]1[C@H](C)OC1=O
Show InChI InChI=1S/C14H25NO4/c1-4-5-6-7-8-9-10(2)18-14(17)15-12-11(3)19-13(12)16/h10-12H,4-9H2,1-3H3,(H,15,17)/t10-,11-,12+/m0/s1
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n/an/a 16n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM233776
PNG
(US9353075, 8)
Show SMILES CC(OC(=O)N[C@@H]1[C@H](C)OC1=O)c1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C19H19NO4/c1-12(24-19(22)20-17-13(2)23-18(17)21)14-8-10-16(11-9-14)15-6-4-3-5-7-15/h3-13,17H,1-2H3,(H,20,22)/t12?,13-,17+/m0/s1
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n/an/a 50n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM233777
PNG
(US9353075, 9)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OC1CCN(CC1)C(=O)c1ccccc1
Show InChI InChI=1S/C17H20N2O5/c1-11-14(16(21)23-11)18-17(22)24-13-7-9-19(10-8-13)15(20)12-5-3-2-4-6-12/h2-6,11,13-14H,7-10H2,1H3,(H,18,22)/t11-,14+/m0/s1
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n/an/a 1.31E+3n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM233778
PNG
(US9353075, 10)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OC1(C)CCCCC1
Show InChI InChI=1S/C12H19NO4/c1-8-9(10(14)16-8)13-11(15)17-12(2)6-4-3-5-7-12/h8-9H,3-7H2,1-2H3,(H,13,15)/t8-,9+/m0/s1
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n/an/a 840n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM233779
PNG
(US9353075, 11)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OC1(C)CCOCC1
Show InChI InChI=1S/C11H17NO5/c1-7-8(9(13)16-7)12-10(14)17-11(2)3-5-15-6-4-11/h7-8H,3-6H2,1-2H3,(H,12,14)/t7-,8+/m0/s1
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n/an/a 4.00E+4n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM233780
PNG
(US9353075, 12)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C15H21NO4/c1-8-12(13(17)19-8)16-14(18)20-15-5-9-2-10(6-15)4-11(3-9)7-15/h8-12H,2-7H2,1H3,(H,16,18)/t8-,9?,10?,11?,12+,15?/m0/s1
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n/an/a 870n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50032446
PNG
(CHEMBL3353542 | US9353075, 15)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCCCc1ccc(F)cc1
Show InChI InChI=1S/C16H20FNO4/c1-11-14(15(19)22-11)18-16(20)21-10-4-2-3-5-12-6-8-13(17)9-7-12/h6-9,11,14H,2-5,10H2,1H3,(H,18,20)/t11-,14+/m0/s1
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n/an/a 240n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50032461
PNG
(CHEMBL3353549 | US9353075, 16)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCCCCCc1ccccc1
Show InChI InChI=1S/C18H25NO4/c1-14-16(17(20)23-14)19-18(21)22-13-9-4-2-3-6-10-15-11-7-5-8-12-15/h5,7-8,11-12,14,16H,2-4,6,9-10,13H2,1H3,(H,19,21)/t14-,16+/m0/s1
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n/an/a 110n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50439664
PNG
(CHEMBL2419814 | US9353075, 17)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCc1ccc(cc1)-c1ccccc1
Show InChI InChI=1S/C18H17NO4/c1-12-16(17(20)23-12)19-18(21)22-11-13-7-9-15(10-8-13)14-5-3-2-4-6-14/h2-10,12,16H,11H2,1H3,(H,19,21)/t12-,16+/m0/s1
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n/an/a 7n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50439655
PNG
(CHEMBL2419828 | US9353075, 18)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCOCc1ccccc1
Show InChI InChI=1S/C15H19NO5/c1-11-13(14(17)21-11)16-15(18)20-9-5-8-19-10-12-6-3-2-4-7-12/h2-4,6-7,11,13H,5,8-10H2,1H3,(H,16,18)/t11-,13+/m0/s1
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n/an/a 50n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50032463
PNG
(CHEMBL3353547 | US9353075, 19)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCCCCC1CCCCC1
Show InChI InChI=1S/C15H25NO4/c1-11-13(14(17)20-11)16-15(18)19-10-6-5-9-12-7-3-2-4-8-12/h11-13H,2-10H2,1H3,(H,16,18)/t11-,13+/m0/s1
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n/an/a 20n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50032464
PNG
(CHEMBL3353546 | US9353075, 20)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OCC(C)(C)CCc1ccccc1
Show InChI InChI=1S/C17H23NO4/c1-12-14(15(19)22-12)18-16(20)21-11-17(2,3)10-9-13-7-5-4-6-8-13/h4-8,12,14H,9-11H2,1-3H3,(H,18,20)/t12-,14+/m0/s1
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n/an/a 3.43E+3n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM233783
PNG
(US9353075, 22)
Show SMILES CC(CCCCc1ccccc1)OC(=O)N[C@@H]1[C@H](C)OC1=O
Show InChI InChI=1S/C17H23NO4/c1-12(8-6-7-11-14-9-4-3-5-10-14)21-17(20)18-15-13(2)22-16(15)19/h3-5,9-10,12-13,15H,6-8,11H2,1-2H3,(H,18,20)/t12?,13-,15+/m0/s1
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n/an/a 30n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM233784
PNG
(US9353075, 23)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OC1(C)CCCC1
Show InChI InChI=1S/C11H17NO4/c1-7-8(9(13)15-7)12-10(14)16-11(2)5-3-4-6-11/h7-8H,3-6H2,1-2H3,(H,12,14)/t7-,8+/m0/s1
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n/an/a 1.23E+3n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50032466
PNG
(CHEMBL3353544 | US9353075, 24)
Show SMILES CCCCC1(COC1)OC(=O)N[C@@H]1[C@H](C)OC1=O
Show InChI InChI=1S/C12H19NO5/c1-3-4-5-12(6-16-7-12)18-11(15)13-9-8(2)17-10(9)14/h8-9H,3-7H2,1-2H3,(H,13,15)/t8-,9+/m0/s1
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n/an/a 3.76E+3n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
N-acylethanolamine-hydrolyzing acid amidase (NAAA)


(Rattus norvegicus (Rat))
BDBM50439652
PNG
(CHEMBL2419809 | US9353075, 25)
Show SMILES C[C@@H]1OC(=O)[C@@H]1NC(=O)OC(C)(C)CCCCc1ccccc1
Show InChI InChI=1S/C18H25NO4/c1-13-15(16(20)22-13)19-17(21)23-18(2,3)12-8-7-11-14-9-5-4-6-10-14/h4-6,9-10,13,15H,7-8,11-12H2,1-3H3,(H,19,21)/t13-,15+/m0/s1
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n/an/a 310n/an/an/an/a7.4n/a



The Regents of the University of California; Fondazione Istituto Italiano Di Technologia; Universita Degli Studi Di Parma; Universita Degli Studi Di Urbino “Carlo Bo”

US Patent


Assay Description
Lysosomal NAAA protein preparation were obtained by homogenizing male Sprague-Dawley rat lungs (Charles River) in 20 mM Tris-HCl buffer pH 7.4 contai...


US Patent US9353075 (2016)


BindingDB Entry DOI: 10.7270/Q23N229Q
More data for this
Ligand-Target Pair
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