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Found 14 Enz. Inhib. hit(s) with Target = 'NAD-dependent protein deacetylase sirtuin-7'
TargetNAD-dependent protein deacetylase sirtuin-7(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234205(US9359293, TA)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-7(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234206(US9359293, TB)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-7(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234207(US9359293, TH)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-7(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM234208(US9359293, TM)
Affinity DataIC50: >2.05E+5nMpH: 8.0Assay Description:Different concentrations of TA, TB, TH, or TM were pre-incubated with 1 μM of the sirtuin and 1 mM NAD in 20 mM Tris-HCl buffer (pH 8.0) with 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetNAD-dependent protein deacetylase sirtuin-7(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM29589(Faridak | LBH-589 | LBH-589B | Panobinostat | US10...)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of SIRT7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-7(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM50463739(CHEMBL4237803)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of SIRT7 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-7(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM50463743(CHEMBL4241370)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of SIRT7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-7(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM50105327(JNJ-26481585 | Quisinostat)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of SIRT7 (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-7(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM50463738(CHEMBL4244764)
Affinity DataKi: >1.00E+4nMAssay Description:Inhibition of SIRT7 (unknown origin)More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-7(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM50518648(CHEMBL4438364)
Affinity DataIC50:  5.00E+3nMAssay Description:Inhibition of tRNA-activated deacetylation activity of recombinant human full length N-terminal His6-tagged SIRT7 expressed in Escherichia coli using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-7(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM50518646(CHEMBL4522166)
Affinity DataIC50:  8.53E+4nMAssay Description:Inhibition of tRNA-activated deacetylation activity of recombinant human full length N-terminal His6-tagged SIRT7 expressed in Escherichia coli using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-7(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM50545085(CHEMBL4643590)
Affinity DataIC50:  7.89E+4nMAssay Description:Inhibition of tRNA-activated His6-tagged human SIRT7 deacetylation activity using acetyl-lysine as substrate in presence of beta-NAD+ after 30 mins b...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-7(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM50518647(CHEMBL4440955)
Affinity DataIC50:  1.11E+4nMAssay Description:Inhibition of tRNA-activated deacetylation activity of recombinant human full length N-terminal His6-tagged SIRT7 expressed in Escherichia coli using...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetNAD-dependent protein deacetylase sirtuin-7(Homo sapiens (Human))
Cornell University

US Patent
LigandPNGBDBM50449710(CHEMBL4170094)
Affinity DataIC50: >1.00E+5nMAssay Description:Inhibition of recombinant human N-terminal His6-tagged SIRT7 (68 to 354 residues) expressed in Escherichia coli Transetta(DE3) using AcIQF as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed