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Found 6002 hits Enz. Inhib. hit(s) with Target = 'P2X purinoceptor 3'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183070
PNG
(US9150546, I-020 | US9688643, I-020 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2cccc(c2)C(F)(F)F)n(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C20H18ClF3N4O2/c1-12(2)28-18(29)26-17(25-16-5-3-4-14(10-16)20(22,23)24)27(19(28)30)11-13-6-8-15(21)9-7-13/h3-10,12H,11H2,1-2H3,(H,25,26,29)
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n/an/a 389n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183071
PNG
(US9150546, I-021 | US9688643, I-021 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2cccc(c2)C(F)(F)F)n(Cc2ccc(C)cc2)c1=O
Show InChI InChI=1S/C21H21F3N4O2/c1-13(2)28-19(29)26-18(25-17-6-4-5-16(11-17)21(22,23)24)27(20(28)30)12-15-9-7-14(3)8-10-15/h4-11,13H,12H2,1-3H3,(H,25,26,29)
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n/an/a 197n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183072
PNG
(US9150546, I-029 | US9688643, I-029 | US9718790, I...)
Show SMILES CCCCn1c(=O)nc(Nc2cccc(c2)C(F)(F)F)n(Cc2ccc(C)cc2)c1=O
Show InChI InChI=1S/C22H23F3N4O2/c1-3-4-12-28-20(30)27-19(26-18-7-5-6-17(13-18)22(23,24)25)29(21(28)31)14-16-10-8-15(2)9-11-16/h5-11,13H,3-4,12,14H2,1-2H3,(H,26,27,30)
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n/an/a 595n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183073
PNG
(US9150546, I-097 | US9688643, I-097 | US9718790, I...)
Show SMILES Cc1ccc(Cn2c(Nc3cccc(c3)C(F)(F)F)nc(=O)n(c2=O)C(C)(C)C)cc1
Show InChI InChI=1S/C22H23F3N4O2/c1-14-8-10-15(11-9-14)13-28-18(27-19(30)29(20(28)31)21(2,3)4)26-17-7-5-6-16(12-17)22(23,24)25/h5-12H,13H2,1-4H3,(H,26,27,30)
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n/an/a 505n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183074
PNG
(US9150546, I-116 | US9688643, I-116 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2ccc(Oc3ccccc3)cc2)n(Cc2ccc(C)cc2)c1=O
Show InChI InChI=1S/C26H26N4O3/c1-18(2)30-25(31)28-24(29(26(30)32)17-20-11-9-19(3)10-12-20)27-21-13-15-23(16-14-21)33-22-7-5-4-6-8-22/h4-16,18H,17H2,1-3H3,(H,27,28,31)
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n/an/a 484n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183075
PNG
(US9150546, I-117 | US9688643, I-117 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2cccc(Cl)c2)n(Cc2ccc(C)cc2)c1=O
Show InChI InChI=1S/C20H21ClN4O2/c1-13(2)25-19(26)23-18(22-17-6-4-5-16(21)11-17)24(20(25)27)12-15-9-7-14(3)8-10-15/h4-11,13H,12H2,1-3H3,(H,22,23,26)
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n/an/a 387n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183076
PNG
(US9150546, I-118 | US9688643, I-118 | US9718790, I...)
Show SMILES CSc1cccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(C)cc2)c1
Show InChI InChI=1S/C21H24N4O2S/c1-14(2)25-20(26)23-19(22-17-6-5-7-18(12-17)28-4)24(21(25)27)13-16-10-8-15(3)9-11-16/h5-12,14H,13H2,1-4H3,(H,22,23,26)
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n/an/a 231n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183077
PNG
(US9150546, I-121 | US9688643, I-121 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(C)cc2)cc1
Show InChI InChI=1S/C23H28N4O3/c1-15(2)27-22(28)25-21(24-19-10-12-20(13-11-19)30-16(3)4)26(23(27)29)14-18-8-6-17(5)7-9-18/h6-13,15-16H,14H2,1-5H3,(H,24,25,28)
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n/an/a 246n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183078
PNG
(US9150546, I-123 | US9688643, I-123 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2ccc3[nH]ccc3c2)n(Cc2ccc(C)cc2)c1=O
Show InChI InChI=1S/C22H23N5O2/c1-14(2)27-21(28)25-20(24-18-8-9-19-17(12-18)10-11-23-19)26(22(27)29)13-16-6-4-15(3)5-7-16/h4-12,14,23H,13H2,1-3H3,(H,24,25,28)
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n/an/a 815n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183079
PNG
(US9150546, I-126 | US9688643, I-126 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2cccc(c2)C(F)(F)F)n(Cc2ccc(F)cc2)c1=O
Show InChI InChI=1S/C20H18F4N4O2/c1-12(2)28-18(29)26-17(25-16-5-3-4-14(10-16)20(22,23)24)27(19(28)30)11-13-6-8-15(21)9-7-13/h3-10,12H,11H2,1-2H3,(H,25,26,29)
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n/an/a 689n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183080
PNG
(US9150546, I-128 | US9688643, I-128 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2ccc(Oc3ccccc3)cc2)n(Cc2ccc(F)cc2)c1=O
Show InChI InChI=1S/C25H23FN4O3/c1-17(2)30-24(31)28-23(29(25(30)32)16-18-8-10-19(26)11-9-18)27-20-12-14-22(15-13-20)33-21-6-4-3-5-7-21/h3-15,17H,16H2,1-2H3,(H,27,28,31)
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n/an/a 840n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183081
PNG
(US9150546, I-130 | US9688643, I-130 | US9718790, I...)
Show SMILES CSc1cccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(F)cc2)c1
Show InChI InChI=1S/C20H21FN4O2S/c1-13(2)25-19(26)23-18(22-16-5-4-6-17(11-16)28-3)24(20(25)27)12-14-7-9-15(21)10-8-14/h4-11,13H,12H2,1-3H3,(H,22,23,26)
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n/an/a 953n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183082
PNG
(US9150546, I-133 | US9688643, I-133 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(F)cc2)cc1
Show InChI InChI=1S/C22H25FN4O3/c1-14(2)27-21(28)25-20(24-18-9-11-19(12-10-18)30-15(3)4)26(22(27)29)13-16-5-7-17(23)8-6-16/h5-12,14-15H,13H2,1-4H3,(H,24,25,28)
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n/an/a 339n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183083
PNG
(US9150546, I-138 | US9688643, I-138 | US9718790, I...)
Show SMILES CCn1c(=O)nc(Nc2cccc(c2)C(F)(F)F)n(Cc2ccc(F)cc2)c1=O
Show InChI InChI=1S/C19H16F4N4O2/c1-2-26-17(28)25-16(24-15-5-3-4-13(10-15)19(21,22)23)27(18(26)29)11-12-6-8-14(20)9-7-12/h3-10H,2,11H2,1H3,(H,24,25,28)
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n/an/a 619n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183084
PNG
(US9150546, I-141 | US9688643, I-141 | US9718790, I...)
Show SMILES CCn1c(=O)nc(Nc2ccc(Oc3ccccc3)cc2)n(Cc2ccc(F)cc2)c1=O
Show InChI InChI=1S/C24H21FN4O3/c1-2-28-23(30)27-22(29(24(28)31)16-17-8-10-18(25)11-9-17)26-19-12-14-21(15-13-19)32-20-6-4-3-5-7-20/h3-15H,2,16H2,1H3,(H,26,27,30)
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n/an/a 685n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183085
PNG
(US9150546, I-162 | US9688643, I-162 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2cccc(c2)C(F)(F)F)n(Cc2ccc(Cl)cn2)c1=O
Show InChI InChI=1S/C19H17ClF3N5O2/c1-11(2)28-17(29)26-16(25-14-5-3-4-12(8-14)19(21,22)23)27(18(28)30)10-15-7-6-13(20)9-24-15/h3-9,11H,10H2,1-2H3,(H,25,26,29)
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n/an/a 379n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183086
PNG
(US9150546, I-164 | US9688643, I-164 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2ccc(Oc3ccccc3)cc2)n(Cc2ccc(Cl)cn2)c1=O
Show InChI InChI=1S/C24H22ClN5O3/c1-16(2)30-23(31)28-22(29(24(30)32)15-19-9-8-17(25)14-26-19)27-18-10-12-21(13-11-18)33-20-6-4-3-5-7-20/h3-14,16H,15H2,1-2H3,(H,27,28,31)
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n/an/a 860n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183087
PNG
(US9150546, I-181 | US9688643, I-181 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2cccc(OC(F)(F)F)c2)n(Cc2ccc(F)cc2)c1=O
Show InChI InChI=1S/C20H18F4N4O3/c1-12(2)28-18(29)26-17(25-15-4-3-5-16(10-15)31-20(22,23)24)27(19(28)30)11-13-6-8-14(21)9-7-13/h3-10,12H,11H2,1-2H3,(H,25,26,29)
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n/an/a 985n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183088
PNG
(US9150546, I-182 | US9688643, I-182 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2cccc(F)c2)n(Cc2ccc(F)cc2)c1=O
Show InChI InChI=1S/C19H18F2N4O2/c1-12(2)25-18(26)23-17(22-16-5-3-4-15(21)10-16)24(19(25)27)11-13-6-8-14(20)9-7-13/h3-10,12H,11H2,1-2H3,(H,22,23,26)
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n/an/a 714n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183089
PNG
(US9150546, I-200 | US9688643, I-200 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C22H25ClN4O3/c1-14(2)27-21(28)25-20(24-18-9-11-19(12-10-18)30-15(3)4)26(22(27)29)13-16-5-7-17(23)8-6-16/h5-12,14-15H,13H2,1-4H3,(H,24,25,28)
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n/an/a 128n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183090
PNG
(US9150546, I-203 | US9688643, I-203 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(F)cc2)cc1Cl
Show InChI InChI=1S/C22H24ClFN4O3/c1-13(2)28-21(29)26-20(25-17-9-10-19(18(23)11-17)31-14(3)4)27(22(28)30)12-15-5-7-16(24)8-6-15/h5-11,13-14H,12H2,1-4H3,(H,25,26,29)
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n/an/a 110n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183091
PNG
(US9150546, I-204 | US9688643, I-204 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(F)cc2)cc1C(F)(F)F
Show InChI InChI=1S/C23H24F4N4O3/c1-13(2)31-21(32)29-20(30(22(31)33)12-15-5-7-16(24)8-6-15)28-17-9-10-19(34-14(3)4)18(11-17)23(25,26)27/h5-11,13-14H,12H2,1-4H3,(H,28,29,32)
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n/an/a 558n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183092
PNG
(US9150546, I-217 | US9688643, I-217 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(C)c(F)c2)cc1
Show InChI InChI=1S/C23H27FN4O3/c1-14(2)28-22(29)26-21(25-18-8-10-19(11-9-18)31-15(3)4)27(23(28)30)13-17-7-6-16(5)20(24)12-17/h6-12,14-15H,13H2,1-5H3,(H,25,26,29)
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n/an/a 268n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183093
PNG
(US9150546, I-218 | US9688643, I-218 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(C)c(c2)[N+]([O-])=O)cc1
Show InChI InChI=1S/C23H27N5O5/c1-14(2)27-22(29)25-21(24-18-8-10-19(11-9-18)33-15(3)4)26(23(27)30)13-17-7-6-16(5)20(12-17)28(31)32/h6-12,14-15H,13H2,1-5H3,(H,24,25,29)
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n/an/a 505n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183094
PNG
(US9150546, I-221 | US9688643, I-221 | US9718790, I...)
Show SMILES COC(=O)c1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(F)cc2)cc1
Show InChI InChI=1S/C21H21FN4O4/c1-13(2)26-20(28)24-19(23-17-10-6-15(7-11-17)18(27)30-3)25(21(26)29)12-14-4-8-16(22)9-5-14/h4-11,13H,12H2,1-3H3,(H,23,24,28)
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n/an/a 276n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183095
PNG
(US9150546, I-223 | US9688643, I-223 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(NC(C)c2ccc(Cl)cc2)n(Cc2ccc(F)cc2)c1=O
Show InChI InChI=1S/C21H22ClFN4O2/c1-13(2)27-20(28)25-19(24-14(3)16-6-8-17(22)9-7-16)26(21(27)29)12-15-4-10-18(23)11-5-15/h4-11,13-14H,12H2,1-3H3,(H,24,25,28)
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n/an/a 909n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183096
PNG
(US9150546, I-227 | US9688643, I-227 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(F)cc2)cc1C#N
Show InChI InChI=1S/C23H24FN5O3/c1-14(2)29-22(30)27-21(28(23(29)31)13-16-5-7-18(24)8-6-16)26-19-9-10-20(32-15(3)4)17(11-19)12-25/h5-11,14-15H,13H2,1-4H3,(H,26,27,30)
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n/an/a 970n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183097
PNG
(US9150546, I-228 | US9688643, I-228 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl
Show InChI InChI=1S/C22H24Cl2N4O3/c1-13(2)28-21(29)26-20(25-17-9-10-19(18(24)11-17)31-14(3)4)27(22(28)30)12-15-5-7-16(23)8-6-15/h5-11,13-14H,12H2,1-4H3,(H,25,26,29)
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n/an/a 31n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183098
PNG
(US9150546, I-234 | US9688643, I-234 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cn2)cc1Cl
Show InChI InChI=1S/C21H23Cl2N5O3/c1-12(2)28-20(29)26-19(25-15-7-8-18(17(23)9-15)31-13(3)4)27(21(28)30)11-16-6-5-14(22)10-24-16/h5-10,12-13H,11H2,1-4H3,(H,25,26,29)
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n/an/a 298n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183099
PNG
(US9150546, I-235 | US9688643, I-235 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)nc2)cc1Cl
Show InChI InChI=1S/C21H23Cl2N5O3/c1-12(2)28-20(29)26-19(25-15-6-7-17(16(22)9-15)31-13(3)4)27(21(28)30)11-14-5-8-18(23)24-10-14/h5-10,12-13H,11H2,1-4H3,(H,25,26,29)
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n/an/a 985n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183100
PNG
(US9150546, I-237 | US9688643, I-237 | US9718790, I...)
Show SMILES COCCOc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl
Show InChI InChI=1S/C22H24Cl2N4O4/c1-14(2)28-21(29)26-20(27(22(28)30)13-15-4-6-16(23)7-5-15)25-17-8-9-19(18(24)12-17)32-11-10-31-3/h4-9,12,14H,10-11,13H2,1-3H3,(H,25,26,29)
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n/an/a 230n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183101
PNG
(US9150546, I-238 | US9688643, I-238 | US9718790, I...)
Show SMILES COC(=O)c1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(F)cc2)cc1Cl
Show InChI InChI=1S/C21H20ClFN4O4/c1-12(2)27-20(29)25-19(24-15-8-9-16(17(22)10-15)18(28)31-3)26(21(27)30)11-13-4-6-14(23)7-5-13/h4-10,12H,11H2,1-3H3,(H,24,25,29)
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n/an/a 658n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183102
PNG
(US9150546, I-239 | US9688643, I-239 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2ccc(OC3CCOCC3)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C24H26Cl2N4O4/c1-15(2)30-23(31)28-22(29(24(30)32)14-16-3-5-17(25)6-4-16)27-18-7-8-21(20(26)13-18)34-19-9-11-33-12-10-19/h3-8,13,15,19H,9-12,14H2,1-2H3,(H,27,28,31)
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n/an/a 116n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183103
PNG
(US9150546, I-240 | US9688643, I-240)
Show SMILES CC(C)n1c(=O)nc(Nc2ccc(Oc3ccccc3)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C25H22Cl2N4O3/c1-16(2)31-24(32)29-23(30(25(31)33)15-17-8-10-18(26)11-9-17)28-19-12-13-22(21(27)14-19)34-20-6-4-3-5-7-20/h3-14,16H,15H2,1-2H3,(H,28,29,32)
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n/an/a 953n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183104
PNG
(US9150546, I-241 | US9688643, I-241 | US9718790, I...)
Show SMILES CCOC(=O)COc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl
Show InChI InChI=1S/C23H24Cl2N4O5/c1-4-33-20(30)13-34-19-10-9-17(11-18(19)25)26-21-27-22(31)29(14(2)3)23(32)28(21)12-15-5-7-16(24)8-6-15/h5-11,14H,4,12-13H2,1-3H3,(H,26,27,31)
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n/an/a 447n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183105
PNG
(US9150546, I-242 | US9688643, I-242 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2ccc(OC3CCNCC3)c(Cl)c2)n(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C24H27Cl2N5O3/c1-15(2)31-23(32)29-22(30(24(31)33)14-16-3-5-17(25)6-4-16)28-18-7-8-21(20(26)13-18)34-19-9-11-27-12-10-19/h3-8,13,15,19,27H,9-12,14H2,1-2H3,(H,28,29,32)
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n/an/a 787n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183106
PNG
(US9150546, I-243 | US9688643, I-243 | US9718790, I...)
Show SMILES COc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1Cl
Show InChI InChI=1S/C20H20Cl2N4O3/c1-12(2)26-19(27)24-18(23-15-8-9-17(29-3)16(22)10-15)25(20(26)28)11-13-4-6-14(21)7-5-13/h4-10,12H,11H2,1-3H3,(H,23,24,27)
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n/an/a 450n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183107
PNG
(US9150546, I-244 | US9688643, I-244 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1F
Show InChI InChI=1S/C22H24ClFN4O3/c1-13(2)28-21(29)26-20(25-17-9-10-19(18(24)11-17)31-14(3)4)27(22(28)30)12-15-5-7-16(23)8-6-15/h5-11,13-14H,12H2,1-4H3,(H,25,26,29)
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n/an/a 45n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183108
PNG
(US9150546, I-245 | US9688643, I-245 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1C#N
Show InChI InChI=1S/C23H24ClN5O3/c1-14(2)29-22(30)27-21(28(23(29)31)13-16-5-7-18(24)8-6-16)26-19-9-10-20(32-15(3)4)17(11-19)12-25/h5-11,14-15H,13H2,1-4H3,(H,26,27,30)
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n/an/a 168n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183109
PNG
(US9150546, I-246 | US9688643, I-246 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2ccc3[nH]c(=O)oc3c2)n(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C20H18ClN5O4/c1-11(2)26-18(27)24-17(22-14-7-8-15-16(9-14)30-19(28)23-15)25(20(26)29)10-12-3-5-13(21)6-4-12/h3-9,11H,10H2,1-2H3,(H,23,28)(H,22,24,27)
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n/an/a 996n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183110
PNG
(US9150546, I-248 | US9688643, I-248 | US9718790, I...)
Show SMILES COC(=O)c1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C21H21ClN4O4/c1-13(2)26-20(28)24-19(23-17-10-6-15(7-11-17)18(27)30-3)25(21(26)29)12-14-4-8-16(22)9-5-14/h4-11,13H,12H2,1-3H3,(H,23,24,28)
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n/an/a 420n/an/an/an/a7.537



SHIONOGI & CO., LTD.

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Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183111
PNG
(US9150546, I-254 | US9688643, I-254 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)s2)cc1F
Show InChI InChI=1S/C20H22ClFN4O3S/c1-11(2)26-19(27)24-18(25(20(26)28)10-14-6-8-17(21)30-14)23-13-5-7-16(15(22)9-13)29-12(3)4/h5-9,11-12H,10H2,1-4H3,(H,23,24,27)
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n/an/a 144n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183112
PNG
(US9150546, I-255 | US9688643, I-255 | US9718790, I...)
Show SMILES CC(C)NC(=O)c1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C23H26ClN5O3/c1-14(2)25-20(30)17-7-11-19(12-8-17)26-21-27-22(31)29(15(3)4)23(32)28(21)13-16-5-9-18(24)10-6-16/h5-12,14-15H,13H2,1-4H3,(H,25,30)(H,26,27,31)
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n/an/a 520n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183113
PNG
(US9150546, I-256 | US9688643, I-256 | US9718790, I...)
Show SMILES CC(C)CNC(=O)c1ccc(Nc2nc(=O)n(C(C)C)c(=O)n2Cc2ccc(Cl)cc2)cc1
Show InChI InChI=1S/C24H28ClN5O3/c1-15(2)13-26-21(31)18-7-11-20(12-8-18)27-22-28-23(32)30(16(3)4)24(33)29(22)14-17-5-9-19(25)10-6-17/h5-12,15-16H,13-14H2,1-4H3,(H,26,31)(H,27,28,32)
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n/an/a 867n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183114
PNG
(US9150546, I-257 | US9688643, I-257 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2ccc(cc2)C(=O)NC2CC2)n(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C23H24ClN5O3/c1-14(2)29-22(31)27-21(28(23(29)32)13-15-3-7-17(24)8-4-15)26-19-9-5-16(6-10-19)20(30)25-18-11-12-18/h3-10,14,18H,11-13H2,1-2H3,(H,25,30)(H,26,27,31)
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n/an/a 682n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183115
PNG
(US9150546, I-258 | US9688643, I-258 | US9718790, I...)
Show SMILES CC(C)n1c(=O)nc(Nc2ccc(cc2)C(=O)NCC2CC2)n(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C24H26ClN5O3/c1-15(2)30-23(32)28-22(29(24(30)33)14-17-5-9-19(25)10-6-17)27-20-11-7-18(8-12-20)21(31)26-13-16-3-4-16/h5-12,15-16H,3-4,13-14H2,1-2H3,(H,26,31)(H,27,28,32)
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n/an/a 683n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183116
PNG
(US9150546, I-266 | US9688643, I-266)
Show SMILES CC(C)n1c(=O)nc(Nc2ccc(cc2)C(=O)Nc2ccccc2)n(Cc2ccc(Cl)cc2)c1=O
Show InChI InChI=1S/C26H24ClN5O3/c1-17(2)32-25(34)30-24(31(26(32)35)16-18-8-12-20(27)13-9-18)29-22-14-10-19(11-15-22)23(33)28-21-6-4-3-5-7-21/h3-15,17H,16H2,1-2H3,(H,28,33)(H,29,30,34)
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n/an/a 861n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183117
PNG
(US9150546, I-269 | US9688643, I-269 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)[nH]c(=O)n2Cc2ccc(Cl)cc2)cc1F
Show InChI InChI=1S/C19H18ClFN4O3/c1-11(2)28-16-8-7-14(9-15(16)21)22-17-23-18(26)24-19(27)25(17)10-12-3-5-13(20)6-4-12/h3-9,11H,10H2,1-2H3,(H2,22,23,24,26,27)
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n/an/a 415n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183118
PNG
(US9150546, I-270 | US9688643, I-270 | US9718790, I...)
Show SMILES COc1cc(Cl)ccc1Cn1c(Nc2ccc(OC(C)C)c(F)c2)nc(=O)n(C(C)C)c1=O
Show InChI InChI=1S/C23H26ClFN4O4/c1-13(2)29-22(30)27-21(26-17-8-9-19(18(25)11-17)33-14(3)4)28(23(29)31)12-15-6-7-16(24)10-20(15)32-5/h6-11,13-14H,12H2,1-5H3,(H,26,27,30)
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n/an/a 271n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
P2X purinoceptor 3


(Homo sapiens (human))
BDBM183119
PNG
(US9150546, I-271 | US9688643, I-271 | US9718790, I...)
Show SMILES CC(C)Oc1ccc(Nc2nc(=O)n(CC3CC3)c(=O)n2Cc2ccc(Cl)cc2)cc1F
Show InChI InChI=1S/C23H24ClFN4O3/c1-14(2)32-20-10-9-18(11-19(20)25)26-21-27-22(30)29(13-15-3-4-15)23(31)28(21)12-16-5-7-17(24)8-6-16/h5-11,14-15H,3-4,12-13H2,1-2H3,(H,26,27,30)
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n/an/a 32n/an/an/an/a7.537



SHIONOGI & CO., LTD.

US Patent


Assay Description
Stably expressing cell line (C6BU-1 cell transfected with human P2X3 receptor gene (GenBank accession number Y07683)) was used. The cells were seeded...


US Patent US9150546 (2015)


BindingDB Entry DOI: 10.7270/Q2416VV1
More data for this
Ligand-Target Pair
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