BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 240 hits Enz. Inhib. hit(s) with Target = 'PAI-1/uPA'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
PAI-1/uPA


(Homo sapiens (Human))
BDBM264533
PNG
(US9718760, C259)
Show SMILES CCOC(=O)C(=O)NCc1ccc(Br)cc1
Show InChI InChI=1S/C11H12BrNO3/c1-2-16-11(15)10(14)13-7-8-3-5-9(12)6-4-8/h3-6H,2,7H2,1H3,(H,13,14)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.26E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264534
PNG
(US9718760, C265)
Show SMILES CCOC(=O)C(=O)NCc1cccc(Cl)c1
Show InChI InChI=1S/C11H12ClNO3/c1-2-16-11(15)10(14)13-7-8-4-3-5-9(12)6-8/h3-6H,2,7H2,1H3,(H,13,14)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.02E+6n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264532
PNG
(US9718760, C256)
Show SMILES CCOC(=O)C(=O)NCc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C12H11ClF3NO3/c1-2-20-11(19)10(18)17-6-7-3-4-9(13)8(5-7)12(14,15)16/h3-5H,2,6H2,1H3,(H,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.14E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264533
PNG
(US9718760, C259)
Show SMILES CCOC(=O)C(=O)NCc1ccc(Br)cc1
Show InChI InChI=1S/C11H12BrNO3/c1-2-16-11(15)10(14)13-7-8-3-5-9(12)6-4-8/h3-6H,2,7H2,1H3,(H,13,14)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.02E+6n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264533
PNG
(US9718760, C259)
Show SMILES CCOC(=O)C(=O)NCc1ccc(Br)cc1
Show InChI InChI=1S/C11H12BrNO3/c1-2-16-11(15)10(14)13-7-8-3-5-9(12)6-4-8/h3-6H,2,7H2,1H3,(H,13,14)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.93E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264532
PNG
(US9718760, C256)
Show SMILES CCOC(=O)C(=O)NCc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C12H11ClF3NO3/c1-2-20-11(19)10(18)17-6-7-3-4-9(13)8(5-7)12(14,15)16/h3-5H,2,6H2,1H3,(H,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.20E+6n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264532
PNG
(US9718760, C256)
Show SMILES CCOC(=O)C(=O)NCc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C12H11ClF3NO3/c1-2-20-11(19)10(18)17-6-7-3-4-9(13)8(5-7)12(14,15)16/h3-5H,2,6H2,1H3,(H,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.20E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264535
PNG
(US9718760, C267)
Show SMILES CCOC(=O)C(=O)NCc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C12H12F3NO3/c1-2-19-11(18)10(17)16-7-8-4-3-5-9(6-8)12(13,14)15/h3-6H,2,7H2,1H3,(H,16,17)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.79E+6n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264536
PNG
(US9718760, C276)
Show SMILES COC(=O)CCC(=O)NCc1ccc(F)c(c1)C(F)(F)F
Show InChI InChI=1S/C13H13F4NO3/c1-21-12(20)5-4-11(19)18-7-8-2-3-10(14)9(6-8)13(15,16)17/h2-3,6H,4-5,7H2,1H3,(H,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.44E+6n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264536
PNG
(US9718760, C276)
Show SMILES COC(=O)CCC(=O)NCc1ccc(F)c(c1)C(F)(F)F
Show InChI InChI=1S/C13H13F4NO3/c1-21-12(20)5-4-11(19)18-7-8-2-3-10(14)9(6-8)13(15,16)17/h2-3,6H,4-5,7H2,1H3,(H,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.28E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264536
PNG
(US9718760, C276)
Show SMILES COC(=O)CCC(=O)NCc1ccc(F)c(c1)C(F)(F)F
Show InChI InChI=1S/C13H13F4NO3/c1-21-12(20)5-4-11(19)18-7-8-2-3-10(14)9(6-8)13(15,16)17/h2-3,6H,4-5,7H2,1H3,(H,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.76E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264537
PNG
(US9718760, C277)
Show SMILES COC(=O)CCC(=O)NCc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C13H13ClF3NO3/c1-21-12(20)5-4-11(19)18-7-8-2-3-10(14)9(6-8)13(15,16)17/h2-3,6H,4-5,7H2,1H3,(H,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.35E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264537
PNG
(US9718760, C277)
Show SMILES COC(=O)CCC(=O)NCc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C13H13ClF3NO3/c1-21-12(20)5-4-11(19)18-7-8-2-3-10(14)9(6-8)13(15,16)17/h2-3,6H,4-5,7H2,1H3,(H,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.62E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264537
PNG
(US9718760, C277)
Show SMILES COC(=O)CCC(=O)NCc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C13H13ClF3NO3/c1-21-12(20)5-4-11(19)18-7-8-2-3-10(14)9(6-8)13(15,16)17/h2-3,6H,4-5,7H2,1H3,(H,18,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.45E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264538
PNG
(US9718760, C288)
Show SMILES COC(=O)CCC(=O)NCc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C13H14F3NO3/c1-20-12(19)6-5-11(18)17-8-9-3-2-4-10(7-9)13(14,15)16/h2-4,7H,5-6,8H2,1H3,(H,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.91E+6n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264538
PNG
(US9718760, C288)
Show SMILES COC(=O)CCC(=O)NCc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C13H14F3NO3/c1-20-12(19)6-5-11(18)17-8-9-3-2-4-10(7-9)13(14,15)16/h2-4,7H,5-6,8H2,1H3,(H,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.06E+6n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264538
PNG
(US9718760, C288)
Show SMILES COC(=O)CCC(=O)NCc1cccc(c1)C(F)(F)F
Show InChI InChI=1S/C13H14F3NO3/c1-20-12(19)6-5-11(18)17-8-9-3-2-4-10(7-9)13(14,15)16/h2-4,7H,5-6,8H2,1H3,(H,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.52E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264539
PNG
(US9718760, C309)
Show SMILES OC(=O)C(=O)NCc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C10H7ClF3NO3/c11-7-2-1-5(3-6(7)10(12,13)14)4-15-8(16)9(17)18/h1-3H,4H2,(H,15,16)(H,17,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.20E+6n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264540
PNG
(US9718760, C280)
Show SMILES ONC(=O)C(=O)NCc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C10H8ClF3N2O3/c11-7-2-1-5(3-6(7)10(12,13)14)4-15-8(17)9(18)16-19/h1-3,19H,4H2,(H,15,17)(H,16,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.05E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264540
PNG
(US9718760, C280)
Show SMILES ONC(=O)C(=O)NCc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C10H8ClF3N2O3/c11-7-2-1-5(3-6(7)10(12,13)14)4-15-8(17)9(18)16-19/h1-3,19H,4H2,(H,15,17)(H,16,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.63E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264540
PNG
(US9718760, C280)
Show SMILES ONC(=O)C(=O)NCc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C10H8ClF3N2O3/c11-7-2-1-5(3-6(7)10(12,13)14)4-15-8(17)9(18)16-19/h1-3,19H,4H2,(H,15,17)(H,16,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.68E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264541
PNG
(US9718760, C300)
Show SMILES Cc1cc(Cl)ccc1CNC(=O)C(=O)NO
Show InChI InChI=1S/C10H11ClN2O3/c1-6-4-8(11)3-2-7(6)5-12-9(14)10(15)13-16/h2-4,16H,5H2,1H3,(H,12,14)(H,13,15)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.49E+6n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264542
PNG
(US9718760, C313)
Show SMILES CC(C)=NNC(=O)C(=O)NCc1cc(F)cc(F)c1
Show InChI InChI=1S/C12H13F2N3O2/c1-7(2)16-17-12(19)11(18)15-6-8-3-9(13)5-10(14)4-8/h3-5H,6H2,1-2H3,(H,15,18)(H,17,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.20E+6n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264542
PNG
(US9718760, C313)
Show SMILES CC(C)=NNC(=O)C(=O)NCc1cc(F)cc(F)c1
Show InChI InChI=1S/C12H13F2N3O2/c1-7(2)16-17-12(19)11(18)15-6-8-3-9(13)5-10(14)4-8/h3-5H,6H2,1-2H3,(H,15,18)(H,17,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.32E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264542
PNG
(US9718760, C313)
Show SMILES CC(C)=NNC(=O)C(=O)NCc1cc(F)cc(F)c1
Show InChI InChI=1S/C12H13F2N3O2/c1-7(2)16-17-12(19)11(18)15-6-8-3-9(13)5-10(14)4-8/h3-5H,6H2,1-2H3,(H,15,18)(H,17,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.90E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264543
PNG
(US9718760, C320)
Show SMILES CONC(=O)C(=O)NCc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C11H10ClF3N2O3/c1-20-17-10(19)9(18)16-5-6-2-3-8(12)7(4-6)11(13,14)15/h2-4H,5H2,1H3,(H,16,18)(H,17,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.29E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264543
PNG
(US9718760, C320)
Show SMILES CONC(=O)C(=O)NCc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C11H10ClF3N2O3/c1-20-17-10(19)9(18)16-5-6-2-3-8(12)7(4-6)11(13,14)15/h2-4H,5H2,1H3,(H,16,18)(H,17,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.13E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264543
PNG
(US9718760, C320)
Show SMILES CONC(=O)C(=O)NCc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C11H10ClF3N2O3/c1-20-17-10(19)9(18)16-5-6-2-3-8(12)7(4-6)11(13,14)15/h2-4H,5H2,1H3,(H,16,18)(H,17,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.93E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264544
PNG
(US9718760, C328)
Show SMILES CON(C)C(=O)C(=O)NCc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C12H12ClF3N2O3/c1-18(21-2)11(20)10(19)17-6-7-3-4-9(13)8(5-7)12(14,15)16/h3-5H,6H2,1-2H3,(H,17,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.13E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264544
PNG
(US9718760, C328)
Show SMILES CON(C)C(=O)C(=O)NCc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C12H12ClF3N2O3/c1-18(21-2)11(20)10(19)17-6-7-3-4-9(13)8(5-7)12(14,15)16/h3-5H,6H2,1-2H3,(H,17,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.45E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264544
PNG
(US9718760, C328)
Show SMILES CON(C)C(=O)C(=O)NCc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C12H12ClF3N2O3/c1-18(21-2)11(20)10(19)17-6-7-3-4-9(13)8(5-7)12(14,15)16/h3-5H,6H2,1-2H3,(H,17,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.18E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264545
PNG
(US9718760, C334)
Show SMILES FC(F)(F)c1cc(CNC(=O)C(=O)NNS(=O)(=O)c2ccccc2)ccc1Cl
Show InChI InChI=1S/C16H13ClF3N3O4S/c17-13-7-6-10(8-12(13)16(18,19)20)9-21-14(24)15(25)22-23-28(26,27)11-4-2-1-3-5-11/h1-8,23H,9H2,(H,21,24)(H,22,25)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.89E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264546
PNG
(US9718760, C240)
Show SMILES CCCCCCNC(=O)C(=O)NN
Show InChI InChI=1S/C8H17N3O2/c1-2-3-4-5-6-10-7(12)8(13)11-9/h2-6,9H2,1H3,(H,10,12)(H,11,13)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 3.84E+6n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264546
PNG
(US9718760, C240)
Show SMILES CCCCCCNC(=O)C(=O)NN
Show InChI InChI=1S/C8H17N3O2/c1-2-3-4-5-6-10-7(12)8(13)11-9/h2-6,9H2,1H3,(H,10,12)(H,11,13)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.10E+6n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264546
PNG
(US9718760, C240)
Show SMILES CCCCCCNC(=O)C(=O)NN
Show InChI InChI=1S/C8H17N3O2/c1-2-3-4-5-6-10-7(12)8(13)11-9/h2-6,9H2,1H3,(H,10,12)(H,11,13)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.21E+6n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264547
PNG
(US9718760, C241)
Show SMILES CCCCCNC(=O)C(=O)NN
Show InChI InChI=1S/C7H15N3O2/c1-2-3-4-5-9-6(11)7(12)10-8/h2-5,8H2,1H3,(H,9,11)(H,10,12)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.93E+6n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264548
PNG
(US9718760, C246)
Show SMILES NNC(=O)C(=O)NCCc1ccc(CO)c(CO)c1
Show InChI InChI=1S/C12H17N3O4/c13-15-12(19)11(18)14-4-3-8-1-2-9(6-16)10(5-8)7-17/h1-2,5,16-17H,3-4,6-7,13H2,(H,14,18)(H,15,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.56E+6n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264549
PNG
(US9718760, C248)
Show SMILES NNC(=O)C(=O)NCc1ccc(F)cc1
Show InChI InChI=1S/C9H10FN3O2/c10-7-3-1-6(2-4-7)5-12-8(14)9(15)13-11/h1-4H,5,11H2,(H,12,14)(H,13,15)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.25E+6n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264549
PNG
(US9718760, C248)
Show SMILES NNC(=O)C(=O)NCc1ccc(F)cc1
Show InChI InChI=1S/C9H10FN3O2/c10-7-3-1-6(2-4-7)5-12-8(14)9(15)13-11/h1-4H,5,11H2,(H,12,14)(H,13,15)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 6.49E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264549
PNG
(US9718760, C248)
Show SMILES NNC(=O)C(=O)NCc1ccc(F)cc1
Show InChI InChI=1S/C9H10FN3O2/c10-7-3-1-6(2-4-7)5-12-8(14)9(15)13-11/h1-4H,5,11H2,(H,12,14)(H,13,15)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 4.78E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264550
PNG
(US9718760, C251)
Show SMILES NNC(=O)C(=O)NCc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C10H9ClF3N3O2/c11-7-2-1-5(3-6(7)10(12,13)14)4-16-8(18)9(19)17-15/h1-3H,4,15H2,(H,16,18)(H,17,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 7.23E+4n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264550
PNG
(US9718760, C251)
Show SMILES NNC(=O)C(=O)NCc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C10H9ClF3N3O2/c11-7-2-1-5(3-6(7)10(12,13)14)4-16-8(18)9(19)17-15/h1-3H,4,15H2,(H,16,18)(H,17,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.17E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264550
PNG
(US9718760, C251)
Show SMILES NNC(=O)C(=O)NCc1ccc(Cl)c(c1)C(F)(F)F
Show InChI InChI=1S/C10H9ClF3N3O2/c11-7-2-1-5(3-6(7)10(12,13)14)4-16-8(18)9(19)17-15/h1-3H,4,15H2,(H,16,18)(H,17,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.08E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264551
PNG
(US9718760, C255)
Show SMILES NNC(=O)C(=O)NCc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C10H10F3N3O3/c11-10(12,13)19-7-3-1-6(2-4-7)5-15-8(17)9(18)16-14/h1-4H,5,14H2,(H,15,17)(H,16,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.92E+6n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264551
PNG
(US9718760, C255)
Show SMILES NNC(=O)C(=O)NCc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C10H10F3N3O3/c11-10(12,13)19-7-3-1-6(2-4-7)5-15-8(17)9(18)16-14/h1-4H,5,14H2,(H,15,17)(H,16,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.57E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264551
PNG
(US9718760, C255)
Show SMILES NNC(=O)C(=O)NCc1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C10H10F3N3O3/c11-10(12,13)19-7-3-1-6(2-4-7)5-15-8(17)9(18)16-14/h1-4H,5,14H2,(H,15,17)(H,16,18)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.79E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264552
PNG
(US9718760, C260)
Show SMILES NNC(=O)C(=O)NCc1ccc(Br)cc1
Show InChI InChI=1S/C9H10BrN3O2/c10-7-3-1-6(2-4-7)5-12-8(14)9(15)13-11/h1-4H,5,11H2,(H,12,14)(H,13,15)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.67E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264552
PNG
(US9718760, C260)
Show SMILES NNC(=O)C(=O)NCc1ccc(Br)cc1
Show InChI InChI=1S/C9H10BrN3O2/c10-7-3-1-6(2-4-7)5-12-8(14)9(15)13-11/h1-4H,5,11H2,(H,12,14)(H,13,15)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 2.94E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264552
PNG
(US9718760, C260)
Show SMILES NNC(=O)C(=O)NCc1ccc(Br)cc1
Show InChI InChI=1S/C9H10BrN3O2/c10-7-3-1-6(2-4-7)5-12-8(14)9(15)13-11/h1-4H,5,11H2,(H,12,14)(H,13,15)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 5.25E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
PAI-1/uPA


(Homo sapiens (Human))
BDBM264553
PNG
(US9718760, C261)
Show SMILES NNC(=O)C(=O)NCc1ccc(F)c(c1)C(F)(F)F
Show InChI InChI=1S/C10H9F4N3O2/c11-7-2-1-5(3-6(7)10(12,13)14)4-16-8(18)9(19)17-15/h1-3H,4,15H2,(H,16,18)(H,17,19)
PDB

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
US Patent
n/an/a 1.03E+5n/an/an/an/a7.425



THE REGENTS OF THE UNIVERSITY OF MICHIGAN; EASTERN MICHIGAN UNIVERSITY

US Patent


Assay Description
To determine the efficacy of various synthesized compounds as PAI-1 inhibitors, a fluorometric plate assay was carried out to measure the half maxima...


US Patent US9718760 (2017)

More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 240 total )  |  Next  |  Last  >>
Jump to: