BindingDB PrimarySearch

Found 27 hits Enz. Inhib. hit(s) with Target = 'Pancreatic lipase'
Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	k_off s^-1	k_on M^-1s^-1	pH	Temp °C
Pancreatic lipase (Homo sapiens)	BDBM50212744 (CHEBI:35020 \| TRIBUTYRIN) Show SMILES CCCC(=O)OCC(COC(=O)CCC)OC(=O)CCC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars		<1	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Tested for hydrolysis with 0.2 ug/mL of PPL (porcine pancreatic lipase), 1.5 ug/mL of colipase and 4 mM sodium taurodeoxycholatet (NaTDC) at a compou...				Citation and Details
TBA					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50212746 (CHEMBL119630) Show SMILES CCCC(=O)O[C@@H]1C[C@@H]2C=CC[C@H]12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars		220	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Tested for hydrolysis with 0.5 ug/mL of PPL (porcine pancreatic lipase), 1.5 ug/mL of colipase and 4 mM of sodium taurodeoxycholatet (NaTDC) at the c...				Citation and Details
TBA					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50212746 (CHEMBL119630) Show SMILES CCCC(=O)O[C@@H]1C[C@@H]2C=CC[C@H]12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars		710	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Tested for hydrolysis with 1.0 ug/mL of PPL (porcine pancreatic lipase), 2.2 ug/mL of colipase and 4 mM of sodium taurodeoxycholatet (NaTDC) at the c...				Citation and Details
TBA					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50212744 (CHEBI:35020 \| TRIBUTYRIN) Show SMILES CCCC(=O)OCC(COC(=O)CCC)OC(=O)CCC Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	KEGG PC cid PC sid UniChem Similars		1.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Tested for hydrolysis with 0.2 ug/mL of PPL (porcine pancreatic lipase) at a compound dose of 0.2 g				Citation and Details
TBA					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50212746 (CHEMBL119630) Show SMILES CCCC(=O)O[C@@H]1C[C@@H]2C=CC[C@H]12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars		2.10E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Tested for hydrolysis with 0.2 ug/mL of PPL (porcine pancreatic lipase) at the compound dose of 0.2 g				Citation and Details
TBA					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50212746 (CHEMBL119630) Show SMILES CCCC(=O)O[C@@H]1C[C@@H]2C=CC[C@H]12 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars		5.70E+3	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
TBA					Assay Description Tested for hydrolysis with 1.0 ug/mL of PPL (porcine pancreatic lipase)at the compound dose of 0.2 g				Citation and Details
TBA					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50381861 (CHEMBL2022676) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	6.70E+4	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of human pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysis				Bioorg Med Chem Lett 22: 3147-51 (2012) Article DOI: 10.1016/j.bmcl.2012.03.048 BindingDB Entry DOI: 10.7270/Q22R3SPF
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50381860 (CHEMBL2022680) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	1.70E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of human pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysis				Bioorg Med Chem Lett 22: 3147-51 (2012) Article DOI: 10.1016/j.bmcl.2012.03.048 BindingDB Entry DOI: 10.7270/Q22R3SPF
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50381859 (CHEMBL2022681) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	3.60E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of human pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysis				Bioorg Med Chem Lett 22: 3147-51 (2012) Article DOI: 10.1016/j.bmcl.2012.03.048 BindingDB Entry DOI: 10.7270/Q22R3SPF
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50381858 (CHEMBL2022679) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	5.50E+5	n/a	n/a	n/a	n/a	n/a	n/a	n/a	n/a
Seoul National University Curated by ChEMBL					Assay Description Inhibition of human pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysis				Bioorg Med Chem Lett 22: 3147-51 (2012) Article DOI: 10.1016/j.bmcl.2012.03.048 BindingDB Entry DOI: 10.7270/Q22R3SPF
Seoul National University Curated by ChEMBL					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50213686 (2-((2E,8E)-deca-2,8-dienoylamino)-3-(5-hydroxy-6-o...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.20E+5	n/a	n/a	n/a	n/a	n/a	n/a
Sinhgad College of Pharmacy Curated by ChEMBL					Assay Description Inhibition of pancreatic lipase				Bioorg Med Chem 15: 4674-99 (2007) Article DOI: 10.1016/j.bmc.2007.04.031 BindingDB Entry DOI: 10.7270/Q24J0FZ9
Sinhgad College of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50213694 ((R)-2-((2E,8E)-deca-2,8-dienoylamino)-3-((R)-5-hyd...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+5	n/a	n/a	n/a	n/a	n/a	n/a
Sinhgad College of Pharmacy Curated by ChEMBL					Assay Description Inhibition of pancreatic lipase				Bioorg Med Chem 15: 4674-99 (2007) Article DOI: 10.1016/j.bmc.2007.04.031 BindingDB Entry DOI: 10.7270/Q24J0FZ9
Sinhgad College of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50213689 ((S)-2-((2E,8E)-deca-2,8-dienoylamino)-3-((S)-5-hyd...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	2.70E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sinhgad College of Pharmacy Curated by ChEMBL					Assay Description Inhibition of pancreatic lipase				Bioorg Med Chem 15: 4674-99 (2007) Article DOI: 10.1016/j.bmc.2007.04.031 BindingDB Entry DOI: 10.7270/Q24J0FZ9
Sinhgad College of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50207383 (CHEMBL3893262) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	4.29E+5	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology and Science Pilani (Pilani Campus) Curated by ChEMBL					Assay Description Inhibition of pancreatic lipase (unknown origin)				Bioorg Med Chem 25: 609-620 (2017) Article DOI: 10.1016/j.bmc.2016.11.031 BindingDB Entry DOI: 10.7270/Q2J968C6
					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50207384 (KOENIMBINE \| Koenimbine) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.69E+5	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology and Science Pilani (Pilani Campus) Curated by ChEMBL					Assay Description Inhibition of pancreatic lipase (unknown origin)				Bioorg Med Chem 25: 609-620 (2017) Article DOI: 10.1016/j.bmc.2016.11.031 BindingDB Entry DOI: 10.7270/Q2J968C6
					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50207385 (CHEBI:6646 \| MAHANIMBINE \| Mahanimbine \| Rel-(+)-M...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.79E+4	n/a	n/a	n/a	n/a	n/a	n/a
Birla Institute of Technology and Science Pilani (Pilani Campus) Curated by ChEMBL					Assay Description Inhibition of pancreatic lipase (unknown origin)				Bioorg Med Chem 25: 609-620 (2017) Article DOI: 10.1016/j.bmc.2016.11.031 BindingDB Entry DOI: 10.7270/Q2J968C6
					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50371232 (CARNOSIC ACID) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase PC cid PC sid UniChem	Article PubMed	n/a	n/a	3.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sinhgad College of Pharmacy Curated by ChEMBL					Assay Description Inhibition of pancreatic lipase				Bioorg Med Chem 15: 4674-99 (2007) Article DOI: 10.1016/j.bmc.2007.04.031 BindingDB Entry DOI: 10.7270/Q24J0FZ9
Sinhgad College of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50213683 (CHEMBL218693 \| carnosol) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL KEGG PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	1.30E+4	n/a	n/a	n/a	n/a	n/a	n/a
Sinhgad College of Pharmacy Curated by ChEMBL					Assay Description Inhibition of pancreatic lipase				Bioorg Med Chem 15: 4674-99 (2007) Article DOI: 10.1016/j.bmc.2007.04.031 BindingDB Entry DOI: 10.7270/Q24J0FZ9
Sinhgad College of Pharmacy Curated by ChEMBL					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50326047 ((6S,9R,12R)-1-((R)-1-((R)-2-((S)-1-((S)-5-amino-2-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	1.60E+4	n/a	n/a	n/a	n/a	n/a	n/a
Laboratory of Molecular Biology, Medical Research Council Curated by ChEMBL					Assay Description Binding affinity to pancreatic lipase				Nat Chem Biol 5: 502-7 (2009) Article DOI: 10.1038/nchembio.184 BindingDB Entry DOI: 10.7270/Q2Z60P9P
					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50138737 (3-(4-Chloro-phenyl)-5-(2,2,2-trifluoro-ethylsulfan...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested to inhibit pancreatic lipase (PL)				J Med Chem 47: 400-10 (2004) Article DOI: 10.1021/jm031004s BindingDB Entry DOI: 10.7270/Q2ZG6RN1
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50138734 (3-(3-(benzyloxy)phenyl)-5-ethoxy-1,3,4-oxadiazol-2...) Show SMILES CCOc1nn(-c2cccc(OCc3ccccc3)c2)c(=O)o1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested to inhibit pancreatic lipase (PL)				J Med Chem 47: 400-10 (2004) Article DOI: 10.1021/jm031004s BindingDB Entry DOI: 10.7270/Q2ZG6RN1
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50138751 (5-Methylsulfanyl-3-(4-trifluoromethoxy-phenyl)-[1,...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested to inhibit pancreatic lipase (PL)				J Med Chem 47: 400-10 (2004) Article DOI: 10.1021/jm031004s BindingDB Entry DOI: 10.7270/Q2ZG6RN1
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50138739 (4-tert-Butyl-N-[4-(5-methoxy-2-oxo-[1,3,4]oxadiazo...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	CHEMBL PC cid PC sid UniChem	Article PubMed	n/a	n/a	>1.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested to inhibit pancreatic lipase (PL)				J Med Chem 47: 400-10 (2004) Article DOI: 10.1021/jm031004s BindingDB Entry DOI: 10.7270/Q2ZG6RN1
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50138735 ((S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-c...) Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N1CCC[C@H](C)C1 Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	>5.00E+4	n/a	n/a	n/a	n/a	n/a	n/a
Novo Nordisk A/S Curated by ChEMBL					Assay Description Compound was tested to inhibit pancreatic lipase (PL)				J Med Chem 47: 400-10 (2004) Article DOI: 10.1021/jm031004s BindingDB Entry DOI: 10.7270/Q2ZG6RN1
Novo Nordisk A/S Curated by ChEMBL					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM24567 ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	0.0400	n/a	n/a	n/a	n/a	n/a	n/a
Toho University Curated by ChEMBL					Assay Description Inhibition of pancreatic lipase assessed as umoles of oleic acic released per millimiter of triolein per hour				J Nat Prod 69: 1577-81 (2006) Article DOI: 10.1021/np060195+ BindingDB Entry DOI: 10.7270/Q2SX6FQ4
Toho University Curated by ChEMBL					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM24567 ((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	Purchase CHEMBL DrugBank PC cid PC sid UniChem Patents Similars	Article PubMed	n/a	n/a	806	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Compound was tested for inhibition of porcine pancreatic lipase				Bioorg Med Chem Lett 8: 977-8 (1998) Article DOI: 10.1016/s0960-894x(98)00140-1
University of Connecticut Curated by ChEMBL					More data for this Ligand-Target Pair
Pancreatic lipase (Homo sapiens)	BDBM50215413 (CHEMBL360443) Show SMILES Show InChI	PDB MMDB Reactome pathway KEGG UniProtKB/SwissProt B.MOAD DrugBank GoogleScholar AffyNet	PC cid PC sid UniChem Similars	Article PubMed	n/a	n/a	3.44E+3	n/a	n/a	n/a	n/a	n/a	n/a
University of Connecticut Curated by ChEMBL					Assay Description Compound was tested for inhibition of porcine pancreatic lipase				Bioorg Med Chem Lett 8: 977-8 (1998) Article DOI: 10.1016/s0960-894x(98)00140-1
University of Connecticut Curated by ChEMBL					More data for this Ligand-Target Pair