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Compile Data Set for Download or QSAR

Found 27 hits Enz. Inhib. hit(s) with Target = 'Pancreatic lipase'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Pancreatic lipase


(Homo sapiens)
BDBM50212744
PNG
(CHEBI:35020 | TRIBUTYRIN)
Show SMILES CCCC(=O)OCC(COC(=O)CCC)OC(=O)CCC
Show InChI InChI=1S/C15H26O6/c1-4-7-13(16)19-10-12(21-15(18)9-6-3)11-20-14(17)8-5-2/h12H,4-11H2,1-3H3
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<1n/an/an/an/an/an/an/an/a


TBA

Assay Description
Tested for hydrolysis with 0.2 ug/mL of PPL (porcine pancreatic lipase), 1.5 ug/mL of colipase and 4 mM sodium taurodeoxycholatet (NaTDC) at a compou...


Citation and Details
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50212746
PNG
(CHEMBL119630)
Show SMILES CCCC(=O)O[C@@H]1C[C@@H]2C=CC[C@H]12
Show InChI InChI=1S/C11H16O2/c1-2-4-11(12)13-10-7-8-5-3-6-9(8)10/h3,5,8-10H,2,4,6-7H2,1H3/t8-,9-,10+/m0/s1
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220n/an/an/an/an/an/an/an/a


TBA

Assay Description
Tested for hydrolysis with 0.5 ug/mL of PPL (porcine pancreatic lipase), 1.5 ug/mL of colipase and 4 mM of sodium taurodeoxycholatet (NaTDC) at the c...


Citation and Details
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50212746
PNG
(CHEMBL119630)
Show SMILES CCCC(=O)O[C@@H]1C[C@@H]2C=CC[C@H]12
Show InChI InChI=1S/C11H16O2/c1-2-4-11(12)13-10-7-8-5-3-6-9(8)10/h3,5,8-10H,2,4,6-7H2,1H3/t8-,9-,10+/m0/s1
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710n/an/an/an/an/an/an/an/a


TBA

Assay Description
Tested for hydrolysis with 1.0 ug/mL of PPL (porcine pancreatic lipase), 2.2 ug/mL of colipase and 4 mM of sodium taurodeoxycholatet (NaTDC) at the c...


Citation and Details
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50212744
PNG
(CHEBI:35020 | TRIBUTYRIN)
Show SMILES CCCC(=O)OCC(COC(=O)CCC)OC(=O)CCC
Show InChI InChI=1S/C15H26O6/c1-4-7-13(16)19-10-12(21-15(18)9-6-3)11-20-14(17)8-5-2/h12H,4-11H2,1-3H3
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1.10E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Tested for hydrolysis with 0.2 ug/mL of PPL (porcine pancreatic lipase) at a compound dose of 0.2 g


Citation and Details
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50212746
PNG
(CHEMBL119630)
Show SMILES CCCC(=O)O[C@@H]1C[C@@H]2C=CC[C@H]12
Show InChI InChI=1S/C11H16O2/c1-2-4-11(12)13-10-7-8-5-3-6-9(8)10/h3,5,8-10H,2,4,6-7H2,1H3/t8-,9-,10+/m0/s1
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2.10E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Tested for hydrolysis with 0.2 ug/mL of PPL (porcine pancreatic lipase) at the compound dose of 0.2 g


Citation and Details
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50212746
PNG
(CHEMBL119630)
Show SMILES CCCC(=O)O[C@@H]1C[C@@H]2C=CC[C@H]12
Show InChI InChI=1S/C11H16O2/c1-2-4-11(12)13-10-7-8-5-3-6-9(8)10/h3,5,8-10H,2,4,6-7H2,1H3/t8-,9-,10+/m0/s1
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5.70E+3n/an/an/an/an/an/an/an/a


TBA

Assay Description
Tested for hydrolysis with 1.0 ug/mL of PPL (porcine pancreatic lipase)at the compound dose of 0.2 g


Citation and Details
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50381861
PNG
(CHEMBL2022676)
Show SMILES CCCCCCCOc1ccc(NC(=O)CCC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1
Show InChI InChI=1S/C35H44N4O5/c1-2-3-4-5-12-23-44-29-19-17-28(18-20-29)37-32(40)21-22-33(41)38-31(25-27-15-10-7-11-16-27)35(43)39-30(34(36)42)24-26-13-8-6-9-14-26/h6-11,13-20,30-31H,2-5,12,21-25H2,1H3,(H2,36,42)(H,37,40)(H,38,41)(H,39,43)/t30-,31-/m0/s1
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6.70E+4n/an/an/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibition of human pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysis


Bioorg Med Chem Lett 22: 3147-51 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.048
BindingDB Entry DOI: 10.7270/Q22R3SPF
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50381860
PNG
(CHEMBL2022680)
Show SMILES CCCCOc1ccc(NC(=O)CCC(=O)N[C@@H](Cc2ccc(O)cc2)C(=O)N[C@@H](Cc2ccccc2)C(N)=O)cc1
Show InChI InChI=1S/C32H38N4O6/c1-2-3-19-42-26-15-11-24(12-16-26)34-29(38)17-18-30(39)35-28(21-23-9-13-25(37)14-10-23)32(41)36-27(31(33)40)20-22-7-5-4-6-8-22/h4-16,27-28,37H,2-3,17-21H2,1H3,(H2,33,40)(H,34,38)(H,35,39)(H,36,41)/t27-,28-/m0/s1
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1.70E+5n/an/an/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibition of human pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysis


Bioorg Med Chem Lett 22: 3147-51 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.048
BindingDB Entry DOI: 10.7270/Q22R3SPF
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50381859
PNG
(CHEMBL2022681)
Show SMILES CCCCOc1ccc(NC(=O)CCC(=O)N[C@H](C(=O)N[C@H](C(N)=O)c2ccc3ccccc3c2)c2ccc3ccccc3c2)cc1
Show InChI InChI=1S/C38H38N4O5/c1-2-3-22-47-32-18-16-31(17-19-32)40-33(43)20-21-34(44)41-36(30-15-13-26-9-5-7-11-28(26)24-30)38(46)42-35(37(39)45)29-14-12-25-8-4-6-10-27(25)23-29/h4-19,23-24,35-36H,2-3,20-22H2,1H3,(H2,39,45)(H,40,43)(H,41,44)(H,42,46)/t35-,36-/m0/s1
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3.60E+5n/an/an/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibition of human pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysis


Bioorg Med Chem Lett 22: 3147-51 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.048
BindingDB Entry DOI: 10.7270/Q22R3SPF
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50381858
PNG
(CHEMBL2022679)
Show SMILES CCCCOc1ccc(NC(=O)CCC(=O)N[C@@H](Cc2ccccc2)C(=O)N[C@@H](Cc2ccc(O)cc2)C(N)=O)cc1
Show InChI InChI=1S/C32H38N4O6/c1-2-3-19-42-26-15-11-24(12-16-26)34-29(38)17-18-30(39)35-28(21-22-7-5-4-6-8-22)32(41)36-27(31(33)40)20-23-9-13-25(37)14-10-23/h4-16,27-28,37H,2-3,17-21H2,1H3,(H2,33,40)(H,34,38)(H,35,39)(H,36,41)/t27-,28-/m0/s1
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5.50E+5n/an/an/an/an/an/an/an/a



Seoul National University

Curated by ChEMBL


Assay Description
Inhibition of human pancreatic lipase using p-nitrophenylbutyrate as substrate by Dixon plot analysis


Bioorg Med Chem Lett 22: 3147-51 (2012)


Article DOI: 10.1016/j.bmcl.2012.03.048
BindingDB Entry DOI: 10.7270/Q22R3SPF
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50213686
PNG
(2-((2E,8E)-deca-2,8-dienoylamino)-3-(5-hydroxy-6-o...)
Show SMILES COC(=O)C(CC1(O)C2OC2C2OC2C1=O)NC(=O)\C=C\CCCC\C=C\C
Show InChI InChI=1S/C20H27NO7/c1-3-4-5-6-7-8-9-10-13(22)21-12(19(24)26-2)11-20(25)17(23)15-14(27-15)16-18(20)28-16/h3-4,9-10,12,14-16,18,25H,5-8,11H2,1-2H3,(H,21,22)/b4-3+,10-9+
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n/an/a 1.20E+5n/an/an/an/an/an/a



Sinhgad College of Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of pancreatic lipase


Bioorg Med Chem 15: 4674-99 (2007)


Article DOI: 10.1016/j.bmc.2007.04.031
BindingDB Entry DOI: 10.7270/Q24J0FZ9
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50213694
PNG
((R)-2-((2E,8E)-deca-2,8-dienoylamino)-3-((R)-5-hyd...)
Show SMILES COC(=O)[C@@H](C[C@@]1(O)C2OC2C2OC2C1=O)NC(=O)\C=C\CCCC\C=C\C
Show InChI InChI=1S/C20H27NO7/c1-3-4-5-6-7-8-9-10-13(22)21-12(19(24)26-2)11-20(25)17(23)15-14(27-15)16-18(20)28-16/h3-4,9-10,12,14-16,18,25H,5-8,11H2,1-2H3,(H,21,22)/b4-3+,10-9+/t12-,14?,15?,16?,18?,20+/m1/s1
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n/an/a 2.70E+5n/an/an/an/an/an/a



Sinhgad College of Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of pancreatic lipase


Bioorg Med Chem 15: 4674-99 (2007)


Article DOI: 10.1016/j.bmc.2007.04.031
BindingDB Entry DOI: 10.7270/Q24J0FZ9
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50213689
PNG
((S)-2-((2E,8E)-deca-2,8-dienoylamino)-3-((S)-5-hyd...)
Show SMILES COC(=O)[C@H](C[C@]1(O)C2OC2C2OC2C1=O)NC(=O)\C=C\CCCC\C=C\C
Show InChI InChI=1S/C20H27NO7/c1-3-4-5-6-7-8-9-10-13(22)21-12(19(24)26-2)11-20(25)17(23)15-14(27-15)16-18(20)28-16/h3-4,9-10,12,14-16,18,25H,5-8,11H2,1-2H3,(H,21,22)/b4-3+,10-9+/t12-,14?,15?,16?,18?,20+/m0/s1
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n/an/a 2.70E+4n/an/an/an/an/an/a



Sinhgad College of Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of pancreatic lipase


Bioorg Med Chem 15: 4674-99 (2007)


Article DOI: 10.1016/j.bmc.2007.04.031
BindingDB Entry DOI: 10.7270/Q24J0FZ9
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50207383
PNG
(CHEMBL3893262)
Show SMILES COc1cc2[nH]c3c4C=CC(C)(C)Oc4c(C)cc3c2cc1OC
Show InChI InChI=1S/C20H21NO3/c1-11-8-14-13-9-16(22-4)17(23-5)10-15(13)21-18(14)12-6-7-20(2,3)24-19(11)12/h6-10,21H,1-5H3
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n/an/a 4.29E+5n/an/an/an/an/an/a



Birla Institute of Technology and Science Pilani (Pilani Campus)

Curated by ChEMBL


Assay Description
Inhibition of pancreatic lipase (unknown origin)


Bioorg Med Chem 25: 609-620 (2017)


Article DOI: 10.1016/j.bmc.2016.11.031
BindingDB Entry DOI: 10.7270/Q2J968C6
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50207384
PNG
(KOENIMBINE | Koenimbine)
Show SMILES COc1ccc2[nH]c3c4C=CC(C)(C)Oc4c(C)cc3c2c1
Show InChI InChI=1S/C19H19NO2/c1-11-9-15-14-10-12(21-4)5-6-16(14)20-17(15)13-7-8-19(2,3)22-18(11)13/h5-10,20H,1-4H3
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n/an/a 1.69E+5n/an/an/an/an/an/a



Birla Institute of Technology and Science Pilani (Pilani Campus)

Curated by ChEMBL


Assay Description
Inhibition of pancreatic lipase (unknown origin)


Bioorg Med Chem 25: 609-620 (2017)


Article DOI: 10.1016/j.bmc.2016.11.031
BindingDB Entry DOI: 10.7270/Q2J968C6
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50207385
PNG
(CHEBI:6646 | MAHANIMBINE | Mahanimbine | Rel-(+)-M...)
Show SMILES CC(C)=CCCC1(C)Oc2c(C)cc3c([nH]c4ccccc34)c2C=C1
Show InChI InChI=1S/C23H25NO/c1-15(2)8-7-12-23(4)13-11-18-21-19(14-16(3)22(18)25-23)17-9-5-6-10-20(17)24-21/h5-6,8-11,13-14,24H,7,12H2,1-4H3
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n/an/a 1.79E+4n/an/an/an/an/an/a



Birla Institute of Technology and Science Pilani (Pilani Campus)

Curated by ChEMBL


Assay Description
Inhibition of pancreatic lipase (unknown origin)


Bioorg Med Chem 25: 609-620 (2017)


Article DOI: 10.1016/j.bmc.2016.11.031
BindingDB Entry DOI: 10.7270/Q2J968C6
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50371232
PNG
(CARNOSIC ACID)
Show SMILES CC(C)c1cc2CC[C@H]3C(C)(C)CCC[C@]3(C(O)=O)c2c(O)c1O
Show InChI InChI=1S/C20H28O4/c1-11(2)13-10-12-6-7-14-19(3,4)8-5-9-20(14,18(23)24)15(12)17(22)16(13)21/h10-11,14,21-22H,5-9H2,1-4H3,(H,23,24)/t14-,20+/m0/s1
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n/an/a 3.60E+4n/an/an/an/an/an/a



Sinhgad College of Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of pancreatic lipase


Bioorg Med Chem 15: 4674-99 (2007)


Article DOI: 10.1016/j.bmc.2007.04.031
BindingDB Entry DOI: 10.7270/Q24J0FZ9
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50213683
PNG
(CHEMBL218693 | carnosol)
Show SMILES CC(C)c1cc2[C@@H]3C[C@H]4C(C)(C)CCC[C@]4(C(=O)O3)c2c(O)c1O
Show InChI InChI=1S/C20H26O4/c1-10(2)11-8-12-13-9-14-19(3,4)6-5-7-20(14,18(23)24-13)15(12)17(22)16(11)21/h8,10,13-14,21-22H,5-7,9H2,1-4H3/t13-,14-,20+/m0/s1
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n/an/a 1.30E+4n/an/an/an/an/an/a



Sinhgad College of Pharmacy

Curated by ChEMBL


Assay Description
Inhibition of pancreatic lipase


Bioorg Med Chem 15: 4674-99 (2007)


Article DOI: 10.1016/j.bmc.2007.04.031
BindingDB Entry DOI: 10.7270/Q24J0FZ9
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50326047
PNG
((6S,9R,12R)-1-((R)-1-((R)-2-((S)-1-((S)-5-amino-2-...)
Show SMILES C[C@@H](O)[C@@H](NC(=O)[C@@H](CCC(N)=O)NC(=O)CNC(=O)[C@H]1CCCN1C(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H]1CCCN1C(=O)[C@H](CCC(N)=O)NC(=O)[C@@H](N)CS)C(=O)N[C@H](CS)C(O)=O
Show InChI InChI=1S/C38H59N13O13S2/c1-18(52)30(35(60)48-24(16-66)38(63)64)49-32(57)21(6-8-27(40)53)45-29(55)14-43-33(58)25-4-2-10-50(25)37(62)23(12-19-13-42-17-44-19)47-34(59)26-5-3-11-51(26)36(61)22(7-9-28(41)54)46-31(56)20(39)15-65/h13,17-18,20-26,30,52,65-66H,2-12,14-16,39H2,1H3,(H2,40,53)(H2,41,54)(H,42,44)(H,43,58)(H,45,55)(H,46,56)(H,47,59)(H,48,60)(H,49,57)(H,63,64)/t18-,20+,21-,22+,23+,24-,25-,26+,30-/m1/s1
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n/an/a 1.60E+4n/an/an/an/an/an/a



Laboratory of Molecular Biology, Medical Research Council

Curated by ChEMBL


Assay Description
Binding affinity to pancreatic lipase


Nat Chem Biol 5: 502-7 (2009)


Article DOI: 10.1038/nchembio.184
BindingDB Entry DOI: 10.7270/Q2Z60P9P
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50138737
PNG
(3-(4-Chloro-phenyl)-5-(2,2,2-trifluoro-ethylsulfan...)
Show SMILES CN(C(=O)n1nc(nc1SCC(F)(F)F)-c1ccc(Cl)cc1)c1ccccc1
Show InChI InChI=1S/C18H14ClF3N4OS/c1-25(14-5-3-2-4-6-14)17(27)26-16(28-11-18(20,21)22)23-15(24-26)12-7-9-13(19)10-8-12/h2-10H,11H2,1H3
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n/an/a>5.00E+4n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Compound was tested to inhibit pancreatic lipase (PL)


J Med Chem 47: 400-10 (2004)


Article DOI: 10.1021/jm031004s
BindingDB Entry DOI: 10.7270/Q2ZG6RN1
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50138734
PNG
(3-(3-(benzyloxy)phenyl)-5-ethoxy-1,3,4-oxadiazol-2...)
Show SMILES CCOc1nn(-c2cccc(OCc3ccccc3)c2)c(=O)o1
Show InChI InChI=1S/C17H16N2O4/c1-2-21-16-18-19(17(20)23-16)14-9-6-10-15(11-14)22-12-13-7-4-3-5-8-13/h3-11H,2,12H2,1H3
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n/an/a>1.00E+4n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Compound was tested to inhibit pancreatic lipase (PL)


J Med Chem 47: 400-10 (2004)


Article DOI: 10.1021/jm031004s
BindingDB Entry DOI: 10.7270/Q2ZG6RN1
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50138751
PNG
(5-Methylsulfanyl-3-(4-trifluoromethoxy-phenyl)-[1,...)
Show SMILES CSc1nc(nn1C(=O)N(C)c1ccccc1)-c1ccc(OC(F)(F)F)cc1
Show InChI InChI=1S/C18H15F3N4O2S/c1-24(13-6-4-3-5-7-13)17(26)25-16(28-2)22-15(23-25)12-8-10-14(11-9-12)27-18(19,20)21/h3-11H,1-2H3
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n/an/a>5.00E+4n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Compound was tested to inhibit pancreatic lipase (PL)


J Med Chem 47: 400-10 (2004)


Article DOI: 10.1021/jm031004s
BindingDB Entry DOI: 10.7270/Q2ZG6RN1
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50138739
PNG
(4-tert-Butyl-N-[4-(5-methoxy-2-oxo-[1,3,4]oxadiazo...)
Show SMILES COc1nn(-c2ccc(NC(=O)c3ccc(cc3)C(C)(C)C)cc2)c(=O)o1
Show InChI InChI=1S/C20H21N3O4/c1-20(2,3)14-7-5-13(6-8-14)17(24)21-15-9-11-16(12-10-15)23-19(25)27-18(22-23)26-4/h5-12H,1-4H3,(H,21,24)
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n/an/a>1.00E+4n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Compound was tested to inhibit pancreatic lipase (PL)


J Med Chem 47: 400-10 (2004)


Article DOI: 10.1021/jm031004s
BindingDB Entry DOI: 10.7270/Q2ZG6RN1
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50138735
PNG
((S)-4-isopropyl-3-methyl-2-(3-methylpiperidine-1-c...)
Show SMILES CC(C)c1c(C)n(oc1=O)C(=O)N1CCC[C@H](C)C1
Show InChI InChI=1S/C14H22N2O3/c1-9(2)12-11(4)16(19-13(12)17)14(18)15-7-5-6-10(3)8-15/h9-10H,5-8H2,1-4H3/t10-/m0/s1
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n/an/a>5.00E+4n/an/an/an/an/an/a



Novo Nordisk A/S

Curated by ChEMBL


Assay Description
Compound was tested to inhibit pancreatic lipase (PL)


J Med Chem 47: 400-10 (2004)


Article DOI: 10.1021/jm031004s
BindingDB Entry DOI: 10.7270/Q2ZG6RN1
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM24567
PNG
((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Show SMILES CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O
Show InChI InChI=1S/C29H53NO5/c1-5-7-9-11-12-13-14-15-16-18-24(34-29(33)26(30-22-31)20-23(3)4)21-27-25(28(32)35-27)19-17-10-8-6-2/h22-27H,5-21H2,1-4H3,(H,30,31)/t24-,25-,26-,27-/m0/s1
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n/an/a 0.0400n/an/an/an/an/an/a



Toho University

Curated by ChEMBL


Assay Description
Inhibition of pancreatic lipase assessed as umoles of oleic acic released per millimiter of triolein per hour


J Nat Prod 69: 1577-81 (2006)


Article DOI: 10.1021/np060195+
BindingDB Entry DOI: 10.7270/Q2SX6FQ4
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM24567
PNG
((2S)-1-[(2S,3S)-3-hexyl-4-oxooxetan-2-yl]tridecan-...)
Show SMILES CCCCCCCCCCC[C@@H](C[C@@H]1OC(=O)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O
Show InChI InChI=1S/C29H53NO5/c1-5-7-9-11-12-13-14-15-16-18-24(34-29(33)26(30-22-31)20-23(3)4)21-27-25(28(32)35-27)19-17-10-8-6-2/h22-27H,5-21H2,1-4H3,(H,30,31)/t24-,25-,26-,27-/m0/s1
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n/an/a 806n/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of porcine pancreatic lipase


Bioorg Med Chem Lett 8: 977-8 (1998)


Article DOI: 10.1016/s0960-894x(98)00140-1
More data for this
Ligand-Target Pair
Pancreatic lipase


(Homo sapiens)
BDBM50215413
PNG
(CHEMBL360443)
Show SMILES CCCCCCCCCCC[C@@H](C[C@@H]1OC(=C)[C@H]1CCCCCC)OC(=O)[C@H](CC(C)C)NC=O
Show InChI InChI=1S/C30H55NO4/c1-6-8-10-12-13-14-15-16-17-19-26(35-30(33)28(31-23-32)21-24(3)4)22-29-27(25(5)34-29)20-18-11-9-7-2/h23-24,26-29H,5-22H2,1-4H3,(H,31,32)/t26-,27+,28-,29-/m0/s1
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n/an/a 3.44E+3n/an/an/an/an/an/a



University of Connecticut

Curated by ChEMBL


Assay Description
Compound was tested for inhibition of porcine pancreatic lipase


Bioorg Med Chem Lett 8: 977-8 (1998)


Article DOI: 10.1016/s0960-894x(98)00140-1
More data for this
Ligand-Target Pair