Compile Data Set for Download or QSAR
maximum 50k data
Found 5285 Enz. Inhib. hit(s) with Target = 'Peroxisome proliferator-activated receptor alpha'
LigandPNGBDBM28667(5-bromo-2-{[3-(1,2,3,4-tetrahydroisoquinoline-2-su...)
Affinity DataIC50:  3.98E+3nMpH: 7.0 T: 2°CAssay Description:Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28668(5-fluoro-2-{[3-(1,2,3,4-tetrahydroisoquinoline-2-s...)
Affinity DataIC50:  6.31E+3nMpH: 7.0 T: 2°CAssay Description:Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28669(2-{[3-(1,2,3,4-tetrahydroisoquinoline-2-sulfonyl)b...)
Affinity DataIC50:  1.59E+3nMpH: 7.0 T: 2°CAssay Description:Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28670(4-bromo-2-{[3-(1,2,3,4-tetrahydroisoquinoline-2-su...)
Affinity DataIC50:  5.01E+3nMpH: 7.0 T: 2°CAssay Description:Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28671(3-methyl-2-{[3-(1,2,3,4-tetrahydroisoquinoline-2-s...)
Affinity DataIC50: >1.00E+4nMpH: 7.0 T: 2°CAssay Description:Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28672(5-chloro-2-({3-[(5-methoxy-1,2,3,4-tetrahydroisoqu...)
Affinity DataIC50:  7.94E+3nMpH: 7.0 T: 2°CAssay Description:Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28673(5-chloro-2-({3-[(5-hydroxy-1,2,3,4-tetrahydroisoqu...)
Affinity DataIC50: >1.00E+4nMpH: 7.0 T: 2°CAssay Description:Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28661(2-{2-methyl-4-[({4-methyl-2-[4-(trifluoromethyl)ph...)
Affinity DataIC50:  2.00E+3nMpH: 7.0 T: 2°CAssay Description:Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28663(2-{[3-(1,2,3,4-tetrahydroisoquinoline-2-sulfonyl)b...)
Affinity DataIC50: >1.00E+4nMpH: 7.0 T: 2°CAssay Description:Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28664(2-methyl-6-{[3-(1,2,3,4-tetrahydroisoquinoline-2-s...)
Affinity DataIC50: >1.00E+4nMpH: 7.0 T: 2°CAssay Description:Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28665(5-methyl-2-{[3-(1,2,3,4-tetrahydroisoquinoline-2-s...)
Affinity DataIC50:  1.00E+4nMpH: 7.0 T: 2°CAssay Description:Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM28666(5-chloro-2-{[3-(1,2,3,4-tetrahydroisoquinoline-2-s...)
Affinity DataIC50:  5.01E+3nMpH: 7.0 T: 2°CAssay Description:Competition-binding curves for test compounds were determined with expressed human PPAR LBD. Plots of inhibitor concentration versus cpm of radioliga...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29868(alkynyl ether, 10)
Affinity DataKi:  210nM ΔG°:  -37.7kJ/mole EC50:  6.10E+3nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29890(alkynyl ether, 32)
Affinity DataKi:  800nM ΔG°:  -34.4kJ/mole EC50: >1.00E+5nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29879(alkynyl ether, 21)
Affinity DataKi:  880nM ΔG°:  -34.2kJ/mole EC50: >1.00E+5nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29888(alkynyl ether, 30)
Affinity DataKi:  930nM ΔG°:  -34.1kJ/mole EC50: >1.00E+5nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29871(phenoxyacetic acid-ether, 13)
Affinity DataKi:  940nM ΔG°:  -34.1kJ/mole EC50: >1.00E+4nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM29877(alkynyl ether, 19)
Affinity DataKi:  960nM ΔG°:  -34.0kJ/mole EC50:  3.90E+3nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29886(alkynyl ether, 28)
Affinity DataKi:  1.00E+3nM ΔG°:  -33.9kJ/mole EC50: >1.00E+5nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29874(phenoxyacetic acid-ether, 16)
Affinity DataKi:  1.10E+3nM ΔG°:  -33.7kJ/mole EC50: >1.00E+4nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29878(alkynyl ether, 20)
Affinity DataKi:  1.10E+3nM ΔG°:  -33.7kJ/mole EC50: >1.00E+5nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29875(phenoxyacetic acid-ether, 17)
Affinity DataKi:  1.20E+3nM ΔG°:  -33.5kJ/mole EC50: >1.00E+4nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29867(phenoxyacetic acid-ether, 9)
Affinity DataKi:  1.20E+3nM ΔG°:  -33.5kJ/mole EC50: >1.00E+4nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29870(phenoxyacetic acid-ether, 12)
Affinity DataKi:  1.20E+3nM ΔG°:  -33.5kJ/mole EC50: >1.00E+4nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29887(alkynyl ether, 29)
Affinity DataKi:  1.30E+3nM ΔG°:  -33.3kJ/mole EC50: >1.00E+5nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29869(phenoxyacetic acid-ether, 11)
Affinity DataKi:  1.30E+3nM ΔG°:  -33.3kJ/mole EC50: >1.00E+4nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29872(phenoxyacetic acid-ether, 14)
Affinity DataKi:  1.30E+3nM ΔG°:  -33.3kJ/mole EC50: >1.00E+4nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29873(phenoxyacetic acid-ether, 15)
Affinity DataKi:  1.30E+3nM ΔG°:  -33.3kJ/mole EC50: >1.00E+4nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29885(alkynyl ether, 27)
Affinity DataKi:  1.70E+3nM ΔG°:  -32.6kJ/mole EC50: >1.00E+5nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29881(alkynyl ether, 23)
Affinity DataKi:  1.70E+3nM ΔG°:  -32.6kJ/mole EC50: >1.00E+5nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29882(alkynyl ether, 24)
Affinity DataKi:  1.70E+3nM ΔG°:  -32.6kJ/mole EC50: >1.00E+5nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29880(alkynyl ether, 22)
Affinity DataKi:  1.90E+3nM ΔG°:  -32.3kJ/mole EC50: >1.00E+5nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29889(alkynyl ether, 31)
Affinity DataKi:  2.00E+3nM ΔG°:  -32.2kJ/mole EC50: >1.00E+5nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29884(alkynyl ether, 26)
Affinity DataKi:  2.00E+3nM ΔG°:  -32.2kJ/mole EC50: >1.00E+5nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29894(alkynyl ether, 36)
Affinity DataKi:  2.60E+3nM ΔG°:  -31.6kJ/mole EC50: >1.00E+5nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29883(alkynyl ether, 25)
Affinity DataKi:  2.90E+3nM ΔG°:  -31.3kJ/mole EC50: >1.00E+5nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29895(alkynyl ether, 37)
Affinity DataKi:  4.10E+3nM ΔG°:  -30.4kJ/mole EC50: >1.00E+5nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29893(alkynyl ether, 35)
Affinity DataKi:  5.50E+3nM ΔG°:  -29.7kJ/mole EC50: >1.00E+5nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29892(alkynyl ether, 34)
Affinity DataKi:  5.90E+3nM ΔG°:  -29.5kJ/mole EC50: >1.00E+5nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM29891(alkynyl ether, 33)
Affinity DataKi:  7.90E+3nM ΔG°:  -28.8kJ/mole EC50: >1.00E+5nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM29876(phenoxyacetic acid-ether, 18)
Affinity DataKi: >1.00E+4nM ΔG°: >-28.3kJ/mole EC50: >1.00E+4nMpH: 7.1 T: 2°CAssay Description:The human PPARalpha ligand binding was directly measured using a scintillation proximity assay. Plates were read on a Packard TopCount. IC50 values f...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM33288(phenylpropanoic acid derivative, 17d | racemic)
Affinity DataIC50:  877nM EC50:  2.60E+3nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM33291(phenylpropanoic acid derivative, 17g | racemic)
Affinity DataEC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM33292(phenylpropanoic acid derivative, 17h | racemic)
Affinity DataEC50: >1.00E+5nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM33293(phenylpropanoic acid derivative, 17i | racemic)
Affinity DataIC50:  24nM EC50:  182nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM33294(phenylpropanoic acid derivative, 17j)
Affinity DataIC50:  34nM EC50:  61nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM33295(phenylpropanoic acid derivative, 17k)
Affinity DataIC50: >3.30E+3nM EC50: >2.00E+4nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM33296(BMC164883 Compound 58 | phenylpropanoic acid deriv...)
Affinity DataIC50: >3.30E+3nM EC50:  5.00E+3nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM33289(phenylpropanoic acid derivative, 17e)
Affinity DataIC50:  899nM EC50:  874nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM33290(phenylpropanoic acid derivative, 17f)
Affinity DataEC50: >2.00E+4nMpH: 7.2 T: 2°CAssay Description:Human PPAR alpha receptor was expressed as recombinant glutathione-S-transferase (GST)-fusion proteins in Escherichia coli. The purified GST-hPPAR al...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
Displayed 1 to 50 (of 5285 total ) | Next | Last >>
Jump to: