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Compile Data Set for Download or QSAR

Found 497 hits Enz. Inhib. hit(s) with Target = 'Phospholipase D (PLD)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM154520
PNG
(1M39 (17a))
Show SMILES COc1cccc(c1)-c1sc2ccccc2c1-c1ccc(O)cc1
Show InChI InChI=1S/C21H16O2S/c1-23-17-6-4-5-15(13-17)21-20(14-9-11-16(22)12-10-14)18-7-2-3-8-19(18)24-21/h2-13,22H,1H3
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PubMed
n/an/a 1.34E+4n/an/an/an/a7.5n/a



Vanderbilt University



Assay Description
Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...


ACS Chem Biol 10: 421-32 (2015)


Article DOI: 10.1021/cb500828m
BindingDB Entry DOI: 10.7270/Q2H70DK8
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM154519
PNG
(Desketoraloxifene (10))
Show SMILES Oc1ccc(cc1)-c1sc2cc(O)ccc2c1-c1ccc(OCCN2CCCCC2)cc1
Show InChI InChI=1S/C27H27NO3S/c29-21-8-4-20(5-9-21)27-26(24-13-10-22(30)18-25(24)32-27)19-6-11-23(12-7-19)31-17-16-28-14-2-1-3-15-28/h4-13,18,29-30H,1-3,14-17H2
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n/an/a 6.10E+3n/an/an/an/a7.5n/a



Vanderbilt University



Assay Description
Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...


ACS Chem Biol 10: 421-32 (2015)


Article DOI: 10.1021/cb500828m
BindingDB Entry DOI: 10.7270/Q2H70DK8
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM75441
PNG
(1-[2-[4-[2-(3-methoxyphenyl)-1-benzothiophen-3-yl]...)
Show SMILES COc1cccc(c1)-c1sc2ccccc2c1-c1ccc(OCCN2CCCC2)cc1
Show InChI InChI=1S/C27H27NO2S/c1-29-23-8-6-7-21(19-23)27-26(24-9-2-3-10-25(24)31-27)20-11-13-22(14-12-20)30-18-17-28-15-4-5-16-28/h2-3,6-14,19H,4-5,15-18H2,1H3
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n/an/a 1.13E+4n/an/an/an/a7.5n/a



Vanderbilt University



Assay Description
Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...


ACS Chem Biol 10: 421-32 (2015)


Article DOI: 10.1021/cb500828m
BindingDB Entry DOI: 10.7270/Q2H70DK8
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM154520
PNG
(1M39 (17a))
Show SMILES COc1cccc(c1)-c1sc2ccccc2c1-c1ccc(O)cc1
Show InChI InChI=1S/C21H16O2S/c1-23-17-6-4-5-15(13-17)21-20(14-9-11-16(22)12-10-14)18-7-2-3-8-19(18)24-21/h2-13,22H,1H3
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n/an/a>2.00E+4n/an/an/an/a7.5n/a



Vanderbilt University



Assay Description
Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...


ACS Chem Biol 10: 421-32 (2015)


Article DOI: 10.1021/cb500828m
BindingDB Entry DOI: 10.7270/Q2H70DK8
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM75442
PNG
(2-[4-[2-(3-methoxyphenyl)-1-benzothiophen-3-yl]phe...)
Show SMILES COc1cccc(c1)-c1sc2ccccc2c1-c1ccc(OCCN(C)C)cc1
Show InChI InChI=1S/C25H25NO2S/c1-26(2)15-16-28-20-13-11-18(12-14-20)24-22-9-4-5-10-23(22)29-25(24)19-7-6-8-21(17-19)27-3/h4-14,17H,15-16H2,1-3H3
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n/an/a 4.70E+3n/an/an/an/a7.5n/a



Vanderbilt University



Assay Description
Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...


ACS Chem Biol 10: 421-32 (2015)


Article DOI: 10.1021/cb500828m
BindingDB Entry DOI: 10.7270/Q2H70DK8
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM75441
PNG
(1-[2-[4-[2-(3-methoxyphenyl)-1-benzothiophen-3-yl]...)
Show SMILES COc1cccc(c1)-c1sc2ccccc2c1-c1ccc(OCCN2CCCC2)cc1
Show InChI InChI=1S/C27H27NO2S/c1-29-23-8-6-7-21(19-23)27-26(24-9-2-3-10-25(24)31-27)20-11-13-22(14-12-20)30-18-17-28-15-4-5-16-28/h2-3,6-14,19H,4-5,15-18H2,1H3
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n/an/a 7.60E+3n/an/an/an/a7.5n/a



Vanderbilt University



Assay Description
Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...


ACS Chem Biol 10: 421-32 (2015)


Article DOI: 10.1021/cb500828m
BindingDB Entry DOI: 10.7270/Q2H70DK8
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM154521
PNG
(22GY (17d))
Show SMILES COc1cccc(c1)-c1sc2ccccc2c1-c1ccc(OCCN2CCOCC2)cc1
Show InChI InChI=1S/C27H27NO3S/c1-29-23-6-4-5-21(19-23)27-26(24-7-2-3-8-25(24)32-27)20-9-11-22(12-10-20)31-18-15-28-13-16-30-17-14-28/h2-12,19H,13-18H2,1H3
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n/an/a>2.00E+4n/an/an/an/a7.5n/a



Vanderbilt University



Assay Description
Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...


ACS Chem Biol 10: 421-32 (2015)


Article DOI: 10.1021/cb500828m
BindingDB Entry DOI: 10.7270/Q2H70DK8
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM154522
PNG
(24F1 (17e))
Show SMILES CN(C)CCOc1ccc(cc1)-c1c(sc2cc(O)ccc12)-c1ccc(O)cc1
Show InChI InChI=1S/C24H23NO3S/c1-25(2)13-14-28-20-10-5-16(6-11-20)23-21-12-9-19(27)15-22(21)29-24(23)17-3-7-18(26)8-4-17/h3-12,15,26-27H,13-14H2,1-2H3
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n/an/a 1.97E+4n/an/an/an/a7.5n/a



Vanderbilt University



Assay Description
Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...


ACS Chem Biol 10: 421-32 (2015)


Article DOI: 10.1021/cb500828m
BindingDB Entry DOI: 10.7270/Q2H70DK8
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM154523
PNG
(24DY (17f))
Show SMILES Oc1ccc(cc1)-c1sc2cc(O)ccc2c1-c1ccc(OCCN2CCCC2)cc1
Show InChI InChI=1S/C26H25NO3S/c28-20-7-3-19(4-8-20)26-25(23-12-9-21(29)17-24(23)31-26)18-5-10-22(11-6-18)30-16-15-27-13-1-2-14-27/h3-12,17,28-29H,1-2,13-16H2
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n/an/a 1.08E+4n/an/an/an/a7.5n/a



Vanderbilt University



Assay Description
Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...


ACS Chem Biol 10: 421-32 (2015)


Article DOI: 10.1021/cb500828m
BindingDB Entry DOI: 10.7270/Q2H70DK8
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM154524
PNG
(23VK (17g))
Show SMILES Oc1ccc(cc1)-c1sc2cc(O)ccc2c1-c1ccc(OCCN2CCCC2=O)cc1
Show InChI InChI=1S/C26H23NO4S/c28-19-7-3-18(4-8-19)26-25(22-12-9-20(29)16-23(22)32-26)17-5-10-21(11-6-17)31-15-14-27-13-1-2-24(27)30/h3-12,16,28-29H,1-2,13-15H2
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n/an/a 2.90E+3n/an/an/an/a7.5n/a



Vanderbilt University



Assay Description
Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...


ACS Chem Biol 10: 421-32 (2015)


Article DOI: 10.1021/cb500828m
BindingDB Entry DOI: 10.7270/Q2H70DK8
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM154525
PNG
(24F0 (17h))
Show SMILES Oc1ccc(cc1)-c1sc2cc(O)ccc2c1-c1ccc(OCCN2CCOCC2)cc1
Show InChI InChI=1S/C26H25NO4S/c28-20-5-1-19(2-6-20)26-25(23-10-7-21(29)17-24(23)32-26)18-3-8-22(9-4-18)31-16-13-27-11-14-30-15-12-27/h1-10,17,28-29H,11-16H2
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n/an/a 1.12E+4n/an/an/an/a7.5n/a



Vanderbilt University



Assay Description
Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...


ACS Chem Biol 10: 421-32 (2015)


Article DOI: 10.1021/cb500828m
BindingDB Entry DOI: 10.7270/Q2H70DK8
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM154526
PNG
(22B1 (17i))
Show SMILES Oc1ccc(cc1)-c1c(sc2ccccc12)-c1cccc(O)c1
Show InChI InChI=1S/C20H14O2S/c21-15-10-8-13(9-11-15)19-17-6-1-2-7-18(17)23-20(19)14-4-3-5-16(22)12-14/h1-12,21-22H
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n/an/a 1.15E+4n/an/an/an/a7.5n/a



Vanderbilt University



Assay Description
Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...


ACS Chem Biol 10: 421-32 (2015)


Article DOI: 10.1021/cb500828m
BindingDB Entry DOI: 10.7270/Q2H70DK8
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM154527
PNG
(2336 (17j))
Show SMILES COc1ccc(cc1)-c1sc2ccccc2c1-c1ccc(O)cc1
Show InChI InChI=1S/C21H16O2S/c1-23-17-12-8-15(9-13-17)21-20(14-6-10-16(22)11-7-14)18-4-2-3-5-19(18)24-21/h2-13,22H,1H3
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n/an/a 1.01E+4n/an/an/an/a7.5n/a



Vanderbilt University



Assay Description
Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...


ACS Chem Biol 10: 421-32 (2015)


Article DOI: 10.1021/cb500828m
BindingDB Entry DOI: 10.7270/Q2H70DK8
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM75443
PNG
(2-[4-[2-(4-methoxyphenyl)-1-benzothiophen-3-yl]phe...)
Show SMILES COc1ccc(cc1)-c1sc2ccccc2c1-c1ccc(OCCN(C)C)cc1
Show InChI InChI=1S/C25H25NO2S/c1-26(2)16-17-28-21-14-8-18(9-15-21)24-22-6-4-5-7-23(22)29-25(24)19-10-12-20(27-3)13-11-19/h4-15H,16-17H2,1-3H3
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n/an/a>2.00E+4n/an/an/an/a7.5n/a



Vanderbilt University



Assay Description
Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...


ACS Chem Biol 10: 421-32 (2015)


Article DOI: 10.1021/cb500828m
BindingDB Entry DOI: 10.7270/Q2H70DK8
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM154528
PNG
(234H (17l))
Show SMILES COc1ccc(cc1)-c1sc2ccccc2c1-c1ccc(OCCN2CCCC2)cc1
Show InChI InChI=1S/C27H27NO2S/c1-29-22-12-10-21(11-13-22)27-26(24-6-2-3-7-25(24)31-27)20-8-14-23(15-9-20)30-19-18-28-16-4-5-17-28/h2-3,6-15H,4-5,16-19H2,1H3
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n/an/a 1.76E+4n/an/an/an/a7.5n/a



Vanderbilt University



Assay Description
Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...


ACS Chem Biol 10: 421-32 (2015)


Article DOI: 10.1021/cb500828m
BindingDB Entry DOI: 10.7270/Q2H70DK8
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM75442
PNG
(2-[4-[2-(3-methoxyphenyl)-1-benzothiophen-3-yl]phe...)
Show SMILES COc1cccc(c1)-c1sc2ccccc2c1-c1ccc(OCCN(C)C)cc1
Show InChI InChI=1S/C25H25NO2S/c1-26(2)15-16-28-20-13-11-18(12-14-20)24-22-9-4-5-10-23(22)29-25(24)19-7-6-8-21(17-19)27-3/h4-14,17H,15-16H2,1-3H3
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n/an/a 2.60E+3n/an/an/an/a7.5n/a



Vanderbilt University



Assay Description
Briefly, PLD activity was measured as the release of free [3H]-choline from [choline-methyl-3H] dipalmitoylphosphatidylcholine ([3H]-DPPC). 3−5...


ACS Chem Biol 10: 421-32 (2015)


Article DOI: 10.1021/cb500828m
BindingDB Entry DOI: 10.7270/Q2H70DK8
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM50423651
PNG
(CHEMBL2304616)
Show SMILES Clc1ccc2n(C3CCN(CCNC(=O)C4C[C@@H]4c4ccccc4)CC3)c(=O)[nH]c2c1
Show InChI InChI=1S/C24H27ClN4O2/c25-17-6-7-22-21(14-17)27-24(31)29(22)18-8-11-28(12-9-18)13-10-26-23(30)20-15-19(20)16-4-2-1-3-5-16/h1-7,14,18-20H,8-13,15H2,(H,26,30)(H,27,31)/t19-,20?/m1/s1
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n/an/a 2n/an/an/an/an/an/a



Vanderbilt University Medical Center

Curated by ChEMBL


Assay Description
Inhibition of human PLD1 in Calu1 cells


Bioorg Med Chem Lett 19: 1916-20 (2009)


Article DOI: 10.1016/j.bmcl.2009.02.057
BindingDB Entry DOI: 10.7270/Q2VM4C5W
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM19441
PNG
(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Show SMILES Oc1ccc(cc1)-c1sc2cc(O)ccc2c1C(=O)c1ccc(OCCN2CCCCC2)cc1
Show InChI InChI=1S/C28H27NO4S/c30-21-8-4-20(5-9-21)28-26(24-13-10-22(31)18-25(24)34-28)27(32)19-6-11-23(12-7-19)33-17-16-29-14-2-1-3-15-29/h4-13,18,30-31H,1-3,14-17H2
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n/an/a 4.30E+3n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D1(PLD1).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM50206160
PNG
(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)
Show SMILES Fc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O
Show InChI InChI=1S/C21H22ClFN4O2/c22-15-3-6-19-18(13-15)25-21(29)27(19)17-7-10-26(11-8-17)12-9-24-20(28)14-1-4-16(23)5-2-14/h1-6,13,17H,7-12H2,(H,24,28)(H,25,29)
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n/an/a 220n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D1(PLD1).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM123744
PNG
(5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imi...)
Show SMILES Fc1ccc2[nH]c(cc2c1)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C23H24FN5O2/c24-16-5-6-18-15(13-16)14-20(26-18)22(30)25-9-12-28-10-7-17(8-11-28)29-21-4-2-1-3-19(21)27-23(29)31/h1-6,13-14,17,26H,7-12H2,(H,25,30)(H,27,31)
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n/an/a 9.5n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D1(PLD1).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM50206157
PNG
(CHEMBL398568 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo...)
Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1cc2ccccc2s1
Show InChI InChI=1S/C23H24N4O2S/c28-22(21-15-16-5-1-4-8-20(16)30-21)24-11-14-26-12-9-17(10-13-26)27-19-7-3-2-6-18(19)25-23(27)29/h1-8,15,17H,9-14H2,(H,24,28)(H,25,29)
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n/an/a 100n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D1(PLD1).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87245
PNG
(CHEMBL492797 | ML272 | N-(2-(4-(2-Oxo-2,3-dihydro-...)
Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C25H26N4O2/c30-24(20-10-9-18-5-1-2-6-19(18)17-20)26-13-16-28-14-11-21(12-15-28)29-23-8-4-3-7-22(23)27-25(29)31/h1-10,17,21H,11-16H2,(H,26,30)(H,27,31)
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n/an/a 81n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D1(PLD1).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM36415
PNG
(4,5-Dibromo-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]...)
Show SMILES Brc1cc(oc1Br)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C19H20Br2N4O3/c20-13-11-16(28-17(13)21)18(26)22-7-10-24-8-5-12(6-9-24)25-15-4-2-1-3-14(15)23-19(25)27/h1-4,11-12H,5-10H2,(H,22,26)(H,23,27)
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n/an/a 79n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D1(PLD1).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM36416
PNG
(3,4-Difluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d...)
Show SMILES Fc1ccc(cc1F)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C21H22F2N4O2/c22-16-6-5-14(13-17(16)23)20(28)24-9-12-26-10-7-15(8-11-26)27-19-4-2-1-3-18(19)25-21(27)29/h1-6,13,15H,7-12H2,(H,24,28)(H,25,29)
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n/an/a 480n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D1(PLD1).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM36417
PNG
(9-Oxo-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidaz...)
Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1cccc2C(=O)c3ccccc3-c12
Show InChI InChI=1S/C28H26N4O3/c33-26-20-7-2-1-6-19(20)25-21(26)8-5-9-22(25)27(34)29-14-17-31-15-12-18(13-16-31)32-24-11-4-3-10-23(24)30-28(32)35/h1-11,18H,12-17H2,(H,29,34)(H,30,35)
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n/an/a 260n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D1(PLD1).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM36418
PNG
(3,4-Dichloro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d...)
Show SMILES Clc1ccc(cc1Cl)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C21H22Cl2N4O2/c22-16-6-5-14(13-17(16)23)20(28)24-9-12-26-10-7-15(8-11-26)27-19-4-2-1-3-18(19)25-21(27)29/h1-6,13,15H,7-12H2,(H,24,28)(H,25,29)
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n/an/a 46n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D1(PLD1).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM36419
PNG
(4-Chloro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imi...)
Show SMILES Clc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C21H23ClN4O2/c22-16-7-5-15(6-8-16)20(27)23-11-14-25-12-9-17(10-13-25)26-19-4-2-1-3-18(19)24-21(26)28/h1-8,17H,9-14H2,(H,23,27)(H,24,28)
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n/an/a 55n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D1(PLD1).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM36420
PNG
(4-Methoxy-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]im...)
Show SMILES COc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C22H26N4O3/c1-29-18-8-6-16(7-9-18)21(27)23-12-15-25-13-10-17(11-14-25)26-20-5-3-2-4-19(20)24-22(26)28/h2-9,17H,10-15H2,1H3,(H,23,27)(H,24,28)
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n/an/a 1.50E+4n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D1(PLD1).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM36422
PNG
(4-Fluoro-N-(4-fluorobenzoyl)-N-(2-(4-(2-oxo-2,3-di...)
Show SMILES Fc1ccc(cc1)C(=O)N(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)C(=O)c1ccc(F)cc1
Show InChI InChI=1S/C28H26F2N4O3/c29-21-9-5-19(6-10-21)26(35)33(27(36)20-7-11-22(30)12-8-20)18-17-32-15-13-23(14-16-32)34-25-4-2-1-3-24(25)31-28(34)37/h1-12,23H,13-18H2,(H,31,37)
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n/an/a 1.40E+3n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D1(PLD1).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM19441
PNG
(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Show SMILES Oc1ccc(cc1)-c1sc2cc(O)ccc2c1C(=O)c1ccc(OCCN2CCCCC2)cc1
Show InChI InChI=1S/C28H27NO4S/c30-21-8-4-20(5-9-21)28-26(24-13-10-22(31)18-25(24)34-28)27(32)19-6-11-23(12-7-19)33-17-16-29-14-2-1-3-15-29/h4-13,18,30-31H,1-3,14-17H2
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n/an/a 3.40E+3n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D2(PLD2).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM50206160
PNG
(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)
Show SMILES Fc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O
Show InChI InChI=1S/C21H22ClFN4O2/c22-15-3-6-19-18(13-15)25-21(29)27(19)17-7-10-26(11-8-17)12-9-24-20(28)14-1-4-16(23)5-2-14/h1-6,13,17H,7-12H2,(H,24,28)(H,25,29)
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n/an/a 310n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D2(PLD2).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM123744
PNG
(5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imi...)
Show SMILES Fc1ccc2[nH]c(cc2c1)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C23H24FN5O2/c24-16-5-6-18-15(13-16)14-20(26-18)22(30)25-9-12-28-10-7-17(8-11-28)29-21-4-2-1-3-19(21)27-23(29)31/h1-6,13-14,17,26H,7-12H2,(H,25,30)(H,27,31)
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n/an/a 17n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D2(PLD2).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM50206157
PNG
(CHEMBL398568 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo...)
Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1cc2ccccc2s1
Show InChI InChI=1S/C23H24N4O2S/c28-22(21-15-16-5-1-4-8-20(16)30-21)24-11-14-26-12-9-17(10-13-26)27-19-7-3-2-6-18(19)25-23(27)29/h1-8,15,17H,9-14H2,(H,24,28)(H,25,29)
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n/an/a 340n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D2(PLD2).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87245
PNG
(CHEMBL492797 | ML272 | N-(2-(4-(2-Oxo-2,3-dihydro-...)
Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C25H26N4O2/c30-24(20-10-9-18-5-1-2-6-19(18)17-20)26-13-16-28-14-11-21(12-15-28)29-23-8-4-3-7-22(23)27-25(29)31/h1-10,17,21H,11-16H2,(H,26,30)(H,27,31)
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n/an/a 240n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D2(PLD2).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM36415
PNG
(4,5-Dibromo-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]...)
Show SMILES Brc1cc(oc1Br)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C19H20Br2N4O3/c20-13-11-16(28-17(13)21)18(26)22-7-10-24-8-5-12(6-9-24)25-15-4-2-1-3-14(15)23-19(25)27/h1-4,11-12H,5-10H2,(H,22,26)(H,23,27)
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n/an/a 170n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D2(PLD2).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM36416
PNG
(3,4-Difluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d...)
Show SMILES Fc1ccc(cc1F)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C21H22F2N4O2/c22-16-6-5-14(13-17(16)23)20(28)24-9-12-26-10-7-15(8-11-26)27-19-4-2-1-3-18(19)25-21(27)29/h1-6,13,15H,7-12H2,(H,24,28)(H,25,29)
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n/an/a 560n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D2(PLD2).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM36417
PNG
(9-Oxo-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imidaz...)
Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1cccc2C(=O)c3ccccc3-c12
Show InChI InChI=1S/C28H26N4O3/c33-26-20-7-2-1-6-19(20)25-21(26)8-5-9-22(25)27(34)29-14-17-31-15-12-18(13-16-31)32-24-11-4-3-10-23(24)30-28(32)35/h1-11,18H,12-17H2,(H,29,34)(H,30,35)
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n/an/a 600n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D2(PLD2).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM36418
PNG
(3,4-Dichloro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d...)
Show SMILES Clc1ccc(cc1Cl)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C21H22Cl2N4O2/c22-16-6-5-14(13-17(16)23)20(28)24-9-12-26-10-7-15(8-11-26)27-19-4-2-1-3-18(19)25-21(27)29/h1-6,13,15H,7-12H2,(H,24,28)(H,25,29)
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n/an/a 250n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D2(PLD2).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM36419
PNG
(4-Chloro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]imi...)
Show SMILES Clc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C21H23ClN4O2/c22-16-7-5-15(6-8-16)20(27)23-11-14-25-12-9-17(10-13-25)26-19-4-2-1-3-18(19)24-21(26)28/h1-8,17H,9-14H2,(H,23,27)(H,24,28)
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n/an/a 130n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D2(PLD2).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM36420
PNG
(4-Methoxy-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]im...)
Show SMILES COc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C22H26N4O3/c1-29-18-8-6-16(7-9-18)21(27)23-12-15-25-13-10-17(11-14-25)26-20-5-3-2-4-19(20)24-22(26)28/h2-9,17H,10-15H2,1H3,(H,23,27)(H,24,28)
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n/an/a>2.00E+4n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D2(PLD2).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM36421
PNG
(CID25105707 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[...)
Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)n1c2ccccc2c2ccccc12
Show InChI InChI=1S/C27H27N5O2/c33-26(32-23-10-4-1-7-20(23)21-8-2-5-11-24(21)32)28-15-18-30-16-13-19(14-17-30)31-25-12-6-3-9-22(25)29-27(31)34/h1-12,19H,13-18H2,(H,28,33)(H,29,34)
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n/an/a 1.00E+3n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D2(PLD2).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM36422
PNG
(4-Fluoro-N-(4-fluorobenzoyl)-N-(2-(4-(2-oxo-2,3-di...)
Show SMILES Fc1ccc(cc1)C(=O)N(CCN1CCC(CC1)n1c2ccccc2[nH]c1=O)C(=O)c1ccc(F)cc1
Show InChI InChI=1S/C28H26F2N4O3/c29-21-9-5-19(6-10-21)26(35)33(27(36)20-7-11-22(30)12-8-20)18-17-32-15-13-23(14-16-32)34-25-4-2-1-3-24(25)31-28(34)37/h1-12,23H,13-18H2,(H,31,37)
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n/an/a 2.20E+3n/an/an/an/an/a37



Vanderbilt University



Assay Description
PLD in vitro enzymatic assay using phospholipase D2(PLD2).


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM19441
PNG
(2-(4-hydroxyphenyl)-3-({4-[2-(piperidin-1-yl)ethox...)
Show SMILES Oc1ccc(cc1)-c1sc2cc(O)ccc2c1C(=O)c1ccc(OCCN2CCCCC2)cc1
Show InChI InChI=1S/C28H27NO4S/c30-21-8-4-20(5-9-21)28-26(24-13-10-22(31)18-25(24)34-28)27(32)19-6-11-23(12-7-19)33-17-16-29-14-2-1-3-15-29/h4-13,18,30-31H,1-3,14-17H2
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n/an/a>2.00E+4n/an/an/an/an/a37



Vanderbilt University



Assay Description
Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM20607
PNG
((2-{4-[(1Z)-1,2-diphenylbut-1-en-1-yl]phenoxy}ethy...)
Show SMILES CC\C(=C(/c1ccccc1)c1ccc(OCCN(C)C)cc1)c1ccccc1
Show InChI InChI=1S/C26H29NO/c1-4-25(21-11-7-5-8-12-21)26(22-13-9-6-10-14-22)23-15-17-24(18-16-23)28-20-19-27(2)3/h5-18H,4,19-20H2,1-3H3/b26-25-
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n/an/a>2.00E+4n/an/an/an/an/a37



Vanderbilt University



Assay Description
Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM50206160
PNG
(CHEMBL245621 | Halopemide | Halopemide, 8 | N-(2-(...)
Show SMILES Fc1ccc(cc1)C(=O)NCCN1CCC(CC1)n1c2ccc(Cl)cc2[nH]c1=O
Show InChI InChI=1S/C21H22ClFN4O2/c22-15-3-6-19-18(13-15)25-21(29)27(19)17-7-10-26(11-8-17)12-9-24-20(28)14-1-4-16(23)5-2-14/h1-6,13,17H,7-12H2,(H,24,28)(H,25,29)
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n/an/a 11n/an/an/an/an/a37



Vanderbilt University



Assay Description
Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM123744
PNG
(5-Fluoro-N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo[d]imi...)
Show SMILES Fc1ccc2[nH]c(cc2c1)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C23H24FN5O2/c24-16-5-6-18-15(13-16)14-20(26-18)22(30)25-9-12-28-10-7-17(8-11-28)29-21-4-2-1-3-19(21)27-23(29)31/h1-6,13-14,17,26H,7-12H2,(H,25,30)(H,27,31)
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n/an/a 33n/an/an/an/an/a37



Vanderbilt University



Assay Description
Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM50206157
PNG
(CHEMBL398568 | N-(2-(4-(2-Oxo-2,3-dihydro-1H-benzo...)
Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1cc2ccccc2s1
Show InChI InChI=1S/C23H24N4O2S/c28-22(21-15-16-5-1-4-8-20(16)30-21)24-11-14-26-12-9-17(10-13-26)27-19-7-3-2-6-18(19)25-23(27)29/h1-8,15,17H,9-14H2,(H,24,28)(H,25,29)
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n/an/a 1.00E+3n/an/an/an/an/a37



Vanderbilt University



Assay Description
Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM87245
PNG
(CHEMBL492797 | ML272 | N-(2-(4-(2-Oxo-2,3-dihydro-...)
Show SMILES O=C(NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O)c1ccc2ccccc2c1
Show InChI InChI=1S/C25H26N4O2/c30-24(20-10-9-18-5-1-2-6-19(18)17-20)26-13-16-28-14-11-21(12-15-28)29-23-8-4-3-7-22(23)27-25(29)31/h1-10,17,21H,11-16H2,(H,26,30)(H,27,31)
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n/an/a 1.00E+3n/an/an/an/an/a37



Vanderbilt University



Assay Description
Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM36415
PNG
(4,5-Dibromo-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d]...)
Show SMILES Brc1cc(oc1Br)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C19H20Br2N4O3/c20-13-11-16(28-17(13)21)18(26)22-7-10-24-8-5-12(6-9-24)25-15-4-2-1-3-14(15)23-19(25)27/h1-4,11-12H,5-10H2,(H,22,26)(H,23,27)
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n/an/a 2.90E+3n/an/an/an/an/a37



Vanderbilt University



Assay Description
Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
Phospholipase D (PLD)


(Homo sapiens (Human))
BDBM36416
PNG
(3,4-Difluoro-N-(2-(4-(2-oxo-2,3-dihydro-1H-benzo[d...)
Show SMILES Fc1ccc(cc1F)C(=O)NCCN1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C21H22F2N4O2/c22-16-6-5-14(13-17(16)23)20(28)24-9-12-26-10-7-15(8-11-26)27-19-4-2-1-3-18(19)25-21(27)29/h1-6,13,15H,7-12H2,(H,24,28)(H,25,29)
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n/an/a 5.00E+3n/an/an/an/an/a37



Vanderbilt University



Assay Description
Phopholipase D1(PLD)enzymatic inhibition assay using PLD1.d311


Nat Chem Biol 5: 108-17 (2009)


Article DOI: 10.1038/nchembio.140
BindingDB Entry DOI: 10.7270/Q2D50KBK
More data for this
Ligand-Target Pair
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