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Found 97 Enz. Inhib. hit(s) with Target = 'Polyphenol oxidase 1'
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM233016(p-Xylidine-bis(dithiocarbamate) sodium salt (II))
Affinity DataKi:  290nM ΔG°:  -37.6kJ/molepH: 6.8 T: 2°CAssay Description:The assay was performed as previously described with slight modifications [Chen et al., J. Agric. Food Chem., 50:4108-12]. The reaction medium was 1 ...More data for this Ligand-Target Pair
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TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM233016(p-Xylidine-bis(dithiocarbamate) sodium salt (II))
Affinity DataKi:  640nM ΔG°:  -35.6kJ/molepH: 6.8 T: 2°CAssay Description:The assay was performed as previously described with slight modifications [Chen et al., J. Agric. Food Chem., 50:4108-12]. The reaction medium was 1 ...More data for this Ligand-Target Pair
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TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM233016(p-Xylidine-bis(dithiocarbamate) sodium salt (II))
Affinity DataKi:  950nM ΔG°:  -35.8kJ/molepH: 6.8 T: 2°CAssay Description:The assay was performed as previously described with slight modifications [Chen et al., J. Agric. Food Chem., 50:4108-12]. The reaction medium was 1 ...More data for this Ligand-Target Pair
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TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM233016(p-Xylidine-bis(dithiocarbamate) sodium salt (II))
Affinity DataKi:  1.05E+3nM ΔG°:  -35.5kJ/molepH: 6.8 T: 2°CAssay Description:The assay was performed as previously described with slight modifications [Chen et al., J. Agric. Food Chem., 50:4108-12]. The reaction medium was 1 ...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
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TargetPolyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L](Agaricus bisporus (Mushroom))
University Of Technology Sydney

LigandPNGBDBM173587((2E)-3-(3,5-dihydroxyphenyl)-1-(3-hydroxynaphthale...)
Affinity DataKi:  3.80E+3nM IC50:  1.04E+4nMpH: 6.8Assay Description:The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L](Agaricus bisporus (Mushroom))
University Of Technology Sydney

LigandPNGBDBM173584((2E)-3-(2,4-dihydroxyphenyl)-1-(3-hydroxynaphthale...)
Affinity DataKi:  4.50E+3nM IC50:  1.44E+4nMpH: 6.8Assay Description:The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM50382706(Benzyldithiocarbamate sodium salt (I) | CHEMBL2023...)
Affinity DataKi:  5.70E+3nM ΔG°:  -31.1kJ/molepH: 6.8 T: 2°CAssay Description:The assay was performed as previously described with slight modifications [Chen et al., J. Agric. Food Chem., 50:4108-12]. The reaction medium was 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM50382706(Benzyldithiocarbamate sodium salt (I) | CHEMBL2023...)
Affinity DataKi:  5.90E+3nM ΔG°:  -31.0kJ/molepH: 6.8 T: 2°CAssay Description:The assay was performed as previously described with slight modifications [Chen et al., J. Agric. Food Chem., 50:4108-12]. The reaction medium was 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM50382706(Benzyldithiocarbamate sodium salt (I) | CHEMBL2023...)
Affinity DataKi:  9.40E+3nM ΔG°:  -28.9kJ/molepH: 6.8 T: 2°CAssay Description:The assay was performed as previously described with slight modifications [Chen et al., J. Agric. Food Chem., 50:4108-12]. The reaction medium was 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L](Agaricus bisporus (Mushroom))
University Of Technology Sydney

LigandPNGBDBM173583((2E)-3-(2,5-dihydroxyphenyl)-1-(3-hydroxynaphthale...)
Affinity DataKi:  1.08E+4nM IC50:  2.04E+4nMpH: 6.8Assay Description:The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L](Agaricus bisporus (Mushroom))
University Of Technology Sydney

LigandPNGBDBM173585((2E)-1-(3-hydroxynaphthalen-2-yl)-3-(2-hydroxy-4-n...)
Affinity DataKi:  1.12E+4nM IC50:  2.29E+4nMpH: 6.8Assay Description:The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...More data for this Ligand-Target Pair
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TargetPolyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L](Agaricus bisporus (Mushroom))
University Of Technology Sydney

LigandPNGBDBM173586((2E)-1-(3-hydroxynaphthalen-2-yl)-3-(4-hydroxy-3-n...)
Affinity DataKi:  1.19E+4nM IC50:  2.56E+4nMpH: 6.8Assay Description:The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1 [N65D,S176D,K211T,P277A,P406L](Agaricus bisporus (Mushroom))
University Of Technology Sydney

LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataKi:  1.22E+4nM IC50:  2.75E+4nMpH: 6.8Assay Description:The mushroom tyrosinase inhibition activity of hydroxy naphthylchalcone compounds was measured using L-DOPA as substrate. The activity assay used 3 m...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM50382706(Benzyldithiocarbamate sodium salt (I) | CHEMBL2023...)
Affinity DataKi:  1.41E+4nM ΔG°:  -27.9kJ/molepH: 6.8 T: 2°CAssay Description:The assay was performed as previously described with slight modifications [Chen et al., J. Agric. Food Chem., 50:4108-12]. The reaction medium was 1 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1 [61-568](Agaricus bisporus (Mushroom))
Shaoyang University

LigandPNGBDBM195539(2-(Benzylideneamino)-5-mercapto-1,3,4-thiadiazole ...)
Affinity DataIC50:  4.92E+4nMpH: 6.8Assay Description:Briefly, 1,3,4-thiadiazole derivatives were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1 [61-568](Agaricus bisporus (Mushroom))
Shaoyang University

LigandPNGBDBM195540(2-((2-Fluorobenzylidene)amino)-5-mercapto-1,3,4-th...)
Affinity DataIC50:  765nMpH: 6.8Assay Description:Briefly, 1,3,4-thiadiazole derivatives were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substra...More data for this Ligand-Target Pair
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TargetPolyphenol oxidase 1 [61-568](Agaricus bisporus (Mushroom))
Shaoyang University

LigandPNGBDBM195541(2-((3-Chlorobenzylidene)amino)-5-mercapto-1,3,4-th...)
Affinity DataIC50:  4.75E+3nMpH: 6.8Assay Description:Briefly, 1,3,4-thiadiazole derivatives were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substra...More data for this Ligand-Target Pair
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TargetPolyphenol oxidase 1 [61-568](Agaricus bisporus (Mushroom))
Shaoyang University

LigandPNGBDBM195542(2-((4-Chlorobenzylidene)amino)-5-mercapto-1,3,4-th...)
Affinity DataIC50:  2.46E+3nMpH: 6.8Assay Description:Briefly, 1,3,4-thiadiazole derivatives were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substra...More data for this Ligand-Target Pair
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TargetPolyphenol oxidase 1 [61-568](Agaricus bisporus (Mushroom))
Shaoyang University

LigandPNGBDBM195543(2-((3,4-Dichlorobenzylidene)amino)-5-mercapto-1,3,...)
Affinity DataIC50:  3.62E+3nMpH: 6.8Assay Description:Briefly, 1,3,4-thiadiazole derivatives were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substra...More data for this Ligand-Target Pair
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TargetPolyphenol oxidase 1 [61-568](Agaricus bisporus (Mushroom))
Shaoyang University

LigandPNGBDBM195544(4-Chloro-2-(((5-mercapto-1,3,4-thiadiazol-2-yl)imi...)
Affinity DataIC50:  1.72E+3nMpH: 6.8Assay Description:Briefly, 1,3,4-thiadiazole derivatives were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1 [61-568](Agaricus bisporus (Mushroom))
Shaoyang University

LigandPNGBDBM195545(4-Bromo-2-(((5-mercapto-1,3,4-thiadiazol-2-yl)imin...)
Affinity DataIC50:  1.97E+3nMpH: 6.8Assay Description:Briefly, 1,3,4-thiadiazole derivatives were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substra...More data for this Ligand-Target Pair
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In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1 [61-568](Agaricus bisporus (Mushroom))
Shaoyang University

LigandPNGBDBM195546(2-((4-(Tert-butyl)benzylidene)amino)-5-mercapto-1,...)
Affinity DataIC50:  1.39E+3nMpH: 6.8Assay Description:Briefly, 1,3,4-thiadiazole derivatives were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substra...More data for this Ligand-Target Pair
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TargetPolyphenol oxidase 1 [61-568](Agaricus bisporus (Mushroom))
Shaoyang University

LigandPNGBDBM195547(2-((2-Nitrobenzylidene)amino)-5-mercapto-1,3,4-thi...)
Affinity DataIC50:  671nMpH: 6.8Assay Description:Briefly, 1,3,4-thiadiazole derivatives were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substra...More data for this Ligand-Target Pair
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TargetPolyphenol oxidase 1 [61-568](Agaricus bisporus (Mushroom))
Shaoyang University

LigandPNGBDBM195548(2-((2-Methoxybenzylidene)amino)-5-mercapto-1,3,4-t...)
Affinity DataIC50:  733nMpH: 6.8Assay Description:Briefly, 1,3,4-thiadiazole derivatives were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substra...More data for this Ligand-Target Pair
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TargetPolyphenol oxidase 1 [61-568](Agaricus bisporus (Mushroom))
Shaoyang University

LigandPNGBDBM195549(2-((3,5-Dimethoxybenzylidene)amino)-5-mercapto-1,3...)
Affinity DataIC50:  5.35E+3nMpH: 6.8Assay Description:Briefly, 1,3,4-thiadiazole derivatives were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substra...More data for this Ligand-Target Pair
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In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1 [61-568](Agaricus bisporus (Mushroom))
Shaoyang University

LigandPNGBDBM195550(2-(((5-Mercapto-1,3,4-thiadiazol-2-yl)imino)methyl...)
Affinity DataIC50:  785nMpH: 6.8Assay Description:Briefly, 1,3,4-thiadiazole derivatives were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1 [61-568](Agaricus bisporus (Mushroom))
Shaoyang University

LigandPNGBDBM195551(4-(((5-Mercapto-1,3,4-thiadiazol-2-yl)imino)methyl...)
Affinity DataIC50:  255nMpH: 6.8Assay Description:Briefly, 1,3,4-thiadiazole derivatives were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1 [61-568](Agaricus bisporus (Mushroom))
Shaoyang University

LigandPNGBDBM195552(4-(((5-Mercapto-1,3,4-thiadiazol-2-yl)imino)methyl...)
Affinity DataIC50:  36nMpH: 6.8Assay Description:Briefly, 1,3,4-thiadiazole derivatives were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1 [61-568](Agaricus bisporus (Mushroom))
Shaoyang University

LigandPNGBDBM195553(4-(((5-Mercapto-1,3,4-thiadiazol-2-yl)imino)methyl...)
Affinity DataIC50:  473nMpH: 6.8Assay Description:Briefly, 1,3,4-thiadiazole derivatives were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1 [61-568](Agaricus bisporus (Mushroom))
Shaoyang University

LigandPNGBDBM195554(2-((2,4,6-Trimethoxybenzylidene)amino)-5-mercapto-...)
Affinity DataIC50:  907nMpH: 6.8Assay Description:Briefly, 1,3,4-thiadiazole derivatives were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1 [61-568](Agaricus bisporus (Mushroom))
Shaoyang University

LigandPNGBDBM195555(2-(((5-(Benzylthio)-1,3,4-thiadiazol-2-yl)imino)me...)
Affinity DataIC50:  2.47E+5nMpH: 6.8Assay Description:Briefly, 1,3,4-thiadiazole derivatives were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substra...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1 [61-568](Agaricus bisporus (Mushroom))
Shaoyang University

LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  2.36E+4nMpH: 6.8Assay Description:Briefly, 1,3,4-thiadiazole derivatives were tested for diphenolase inhibitory activity of tyrosinase using L-DOPA (dihydroxyphenylalanine) as substra...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM233165(3-Methyl-2-butenylbenzoate (1))
Affinity DataIC50:  8.34E+4nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using the SpectraMax 340 microplate reader (Molecular Devices, CA) accordi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM233166(3-Methyl-2-butenyl-4-hydroxybenzoate (2))
Affinity DataIC50:  1.48E+4nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using the SpectraMax 340 microplate reader (Molecular Devices, CA) accordi...More data for this Ligand-Target Pair
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TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM233167(4-Nitro-phenyl-(4-nitro-2-trifluoromethyl)-benzoat...)
Affinity DataIC50:  2.97E+4nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using the SpectraMax 340 microplate reader (Molecular Devices, CA) accordi...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM233168(N-(2-Hydroxy-ethyl)-3,5-dinitro-benzamide (7))
Affinity DataIC50:  1.09E+3nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using the SpectraMax 340 microplate reader (Molecular Devices, CA) accordi...More data for this Ligand-Target Pair
Ligand InfoKEGGPC cidPC sid
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM233169(N-(2-Bromo-ethyl)-3,5-dinitro-benzamide (8))
Affinity DataIC50:  3.08E+3nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using the SpectraMax 340 microplate reader (Molecular Devices, CA) accordi...More data for this Ligand-Target Pair
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TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM233170(N-Hydroxy-4,N-dimethyl-benzamide (9))
Affinity DataIC50:  2.09E+3nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using the SpectraMax 340 microplate reader (Molecular Devices, CA) accordi...More data for this Ligand-Target Pair
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TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM233171(N-Ethyl-benzamide (10))
Affinity DataIC50:  1.18E+4nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using the SpectraMax 340 microplate reader (Molecular Devices, CA) accordi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  1.67E+4nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using the SpectraMax 340 microplate reader (Molecular Devices, CA) accordi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM50198715((2S)-2-amino-3-(3-hydroxy-4-oxopyridin-1(4H)-yl)pr...)
Affinity DataIC50:  3.68E+3nMpH: 6.8 T: 2°CAssay Description:Tyrosinase inhibition assays were performed in a 96-well microplate format using the SpectraMax 340 microplate reader (Molecular Devices, CA) accordi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM240723(US9422261, Compound 1)
Affinity DataIC50:  90nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM240724(US9422261, Compound 2)
Affinity DataIC50:  400nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM240725(US9422261, Compound 3)
Affinity DataIC50:  200nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM240726(US9422261, Compound 4)
Affinity DataIC50:  80nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM240727(US9422261, Compound 5)
Affinity DataIC50:  1.50E+3nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM50031467(5-HYDROXY-2-(HYDROXYMETHYL)-4H-PYRAN-4-ONE | 5-Hyd...)
Affinity DataIC50:  1.50E+4nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM50248158(CHEMBL450195 | N-butylresorcinol | US8993596, 4-Bu...)
Affinity DataIC50:  1.00E+3nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM240728(US9422261, Arbutin)
Affinity DataIC50:  9.00E+4nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
In DepthDetails US Patent
TargetPolyphenol oxidase 1(Agaricus bisporus (White button mushroom))
University Of Tehran

LigandPNGBDBM240729(US9422261, Unigen resorcinol derivative | US968291...)
Affinity DataIC50:  2.00E+3nMpH: 6.8Assay Description:Reader: Synergy HT program: tyrosinase 280-490 kinetics: kinetics over 45 minutes, reading at t=10 minutes, Tests in transparent 96-well plates, Phos...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails US Patent
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