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Found 510 Enz. Inhib. hit(s) with Target = 'Protein kinase C zeta type'
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM218804(PS312)
Affinity DataIC50:  4.41E+4nMpH: 7.4Assay Description:Interaction assays were performed using the Alpha-Screen (amplified luminescent proximity homogeneous assay) technology, as described previously.19,2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM218807(PS432)
Affinity DataIC50:  1.85E+4nMpH: 7.4Assay Description:Interaction assays were performed using the Alpha-Screen (amplified luminescent proximity homogeneous assay) technology, as described previously.19,2...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM218806(PS267)
Affinity DataIC50:  1.78E+4nMpH: 7.4Assay Description:Interaction assays were performed using the Alpha-Screen (amplified luminescent proximity homogeneous assay) technology, as described previously.19,2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM2579((2S,3R,4R,6R)-3-methoxy-2-methyl-4-(methylamino)-2...)
Affinity DataIC50:  570nMpH: 7.4 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM15022(3-[(2S)-2-amino-3-({5-[(E)-2-(pyridin-4-yl)ethenyl...)
Affinity DataIC50:  930nMpH: 7.4 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM218805(PS212)
Affinity DataIC50:  2.05E+4nMpH: 7.4Assay Description:Interaction assays were performed using the Alpha-Screen (amplified luminescent proximity homogeneous assay) technology, as described previously.19,2...More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35171(indazole-benzimidazole, 7)
Affinity DataIC50:  5.52E+3nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35172(indazole-benzimidazole, 8)
Affinity DataIC50:  1.90E+4nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35173(indazole-benzimidazole, 9)
Affinity DataIC50:  5.18nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35174(indazole-benzimidazole, 10)
Affinity DataIC50:  1.51E+3nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35175(indazole-benzimidazole, 11)
Affinity DataIC50:  55.5nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35176(indazole-benzimidazole, 12)
Affinity DataIC50:  51.3nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35177(indazole-benzimidazole, 13)
Affinity DataIC50:  3.11E+4nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35178(indazole-benzimidazole, 14)
Affinity DataIC50:  8.80E+3nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35179(indazole-benzimidazole, 15)
Affinity DataIC50:  585nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35180(indazole-benzimidazole, 16)
Affinity DataIC50:  1.31E+3nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35181(indazole-benzimidazole, 17)
Affinity DataIC50:  23.3nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35182(indazole-benzimidazole, 18)
Affinity DataIC50:  2.73E+4nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35183(indazole-benzimidazole, 19)
Affinity DataIC50:  1.36E+4nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35184(indazole-benzimidazole, 20)
Affinity DataIC50:  1.18E+4nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35185(indazole-benzimidazole, 21)
Affinity DataIC50:  8.93E+3nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35186(indazole-benzimidazole, 22)
Affinity DataIC50:  4.08E+3nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35187(indazole-benzimidazole, 23)
Affinity DataIC50:  6.84E+3nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35188(indazole-benzimidazole, 24)
Affinity DataIC50:  1.07E+3nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35189(indazole-benzimidazole, 25)
Affinity DataIC50:  3.02E+3nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35170(indazole-benzimidazole, 6)
Affinity DataIC50:  1.24E+4nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35169(indazole-benzimidazole, 5)
Affinity DataIC50:  290nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35168(indazole-benzimidazole, 4)
Affinity DataIC50:  5.60nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35167(indazole-benzimidazole, 3)
Affinity DataIC50:  2.26nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM35166(indazole-benzimidazole, 1)
Affinity DataIC50:  22nMpH: 7.5 T: 2°CAssay Description:Protein kinase C (PKC), zeta activity was measured by following the phosphorylation of a biotinylated peptide substrate in the presence of ATP using ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM16954(6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]-2-chl...)
Affinity DataIC50: >5.00E+3nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM16958(6-{5-[(2S)-2-amino-3-(1H-indol-3-yl)propoxy]-2-eth...)
Affinity DataIC50:  8.90E+3nMpH: 7.5 T: 2°CAssay Description:The kinase assay uses purified recombinant enzyme and a biotinylated peptide as substrate. The biotinylated peptides were immobilized on streptavidi...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Rattus norvegicus)
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50478562(CHEMBL502491)
Affinity DataKi:  500nMAssay Description:Displacement of radiolabeled PDBU from PKC in rat forebrainMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM50427363(CHEMBL2326002)
Affinity DataKi: >5.00E+3nMAssay Description:Inhibition of PKC zeta (unknown origin)More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM50224883(7-chloro-3-oxo-8-[(thiazol-5-ylmethyl)-amino]-11,1...)
Affinity DataKi: >8.33E+3nMAssay Description:Inhibition of PKC zetaMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Rattus norvegicus)
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50241867(((2R,3R,4R,5R,6R)-6-(3,4-dihydroxyphenethoxy)-5-hy...)
Affinity DataKi:  2.20E+4nMAssay Description:Displacement of [gamma32P]ATP from rat brain PKC by competitive Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Rattus norvegicus)
Sterling Research Group

Curated by ChEMBL
LigandPNGBDBM50241867(((2R,3R,4R,5R,6R)-6-(3,4-dihydroxyphenethoxy)-5-hy...)
Affinity DataKi:  2.80E+4nMAssay Description:Inhibition of rat brain PKC using histone type 3-S as substrate by noncompetitive Lineweaver-Burke plot analysisMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM3149(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)
Affinity DataIC50:  3.50E+3nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM3150(2-{[2,6-dihydroxy-4-({[(1R,2R)-2-[(4-hydroxybenzen...)
Affinity DataIC50: >1.50E+5nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM3151(2-{[2,6-dihydroxy-4-({[(3R,4R)-3-[(4-hydroxybenzen...)
Affinity DataIC50: >1.50E+5nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM3152(2-{[2,6-dihydroxy-4-({[(3R,4R)-4-[(4-hydroxybenzen...)
Affinity DataIC50: >150nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM3153(2-{[2,6-dihydroxy-4-({[(1R,2R)-2-[(4-hydroxybenzen...)
Affinity DataIC50:  2.20E+4nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM3154(2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...)
Affinity DataIC50:  3.70E+4nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM3154(2-({2,6-dihydroxy-4-[({3-[(4-hydroxybenzene)amido]...)
Affinity DataIC50: >5.00E+4nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM3156(2-{[2,6-dihydroxy-4-({[(3S,5R)-2-[(4-hydroxybenzen...)
Affinity DataIC50: >5.00E+4nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM3156(2-{[2,6-dihydroxy-4-({[(3S,5R)-2-[(4-hydroxybenzen...)
Affinity DataIC50: >5.00E+4nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM3158(2-{[2,6-dihydroxy-4-({[(4S)-3-[(4-hydroxybenzene)a...)
Affinity DataIC50:  2.20E+4nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM3159(2-{[2,6-dihydroxy-4-({[(4S)-3-[(4-hydroxybenzene)a...)
Affinity DataIC50: >5.00E+4nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM3160(2-{[2,6-dihydroxy-4-({[(8R,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50:  3.70E+4nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article
TargetProtein kinase C zeta type(Homo sapiens (Human))
Universitätsklinikum Frankfurt

LigandPNGBDBM3161(2-{[2,6-dihydroxy-4-({[(8S,9R)-9-[(4-hydroxybenzen...)
Affinity DataIC50: >5.00E+4nMAssay Description:PKC was assayed by quantitating the incorporation of 32P from [gamma-32P]ATP into histone type IIIs.More data for this Ligand-Target Pair
In DepthDetails Article
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