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Compile Data Set for Download or QSAR

Found 495 hits Enz. Inhib. hit(s) with Target = 'Ribosomal protein S6 kinase alpha 2'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM25017
PNG
(2-[(3,5-difluoro-4-hydroxyphenyl)amino]-5,7-dimeth...)
Show SMILES CC(C)CCN1C(C)C(=O)N(C)c2cnc(Nc3cc(F)c(O)c(F)c3)nc12
Show InChI InChI=1S/C19H23F2N5O2/c1-10(2)5-6-26-11(3)18(28)25(4)15-9-22-19(24-17(15)26)23-12-7-13(20)16(27)14(21)8-12/h7-11,27H,5-6H2,1-4H3,(H,22,23,24)
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PubMed
n/an/a 18n/an/an/an/a7.522



University of Dundee



Assay Description
IC50 is the inhibitor concentration which inhibits 50% of kinase activity that catalyzes the transfer of the terminal phosphate from [gamma-33P] labe...


Biochem J 401: 29-38 (2007)


Article DOI: 10.1042/BJ20061088
BindingDB Entry DOI: 10.7270/Q25Q4TD7
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM50361874
PNG
(CHEMBL1938783 | US9150577, 1)
Show SMILES Clc1cccc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3c2)c1
Show InChI InChI=1S/C19H16ClN3O2/c20-14-3-1-4-15(11-14)22-18(24)13-6-5-12-9-17-19(25)21-7-2-8-23(17)16(12)10-13/h1,3-6,9-11H,2,7-8H2,(H,21,25)(H,22,24)
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n/an/a 270n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184158
PNG
(US9150577, 2)
Show SMILES Cc1cc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3c2)no1
Show InChI InChI=1S/C17H16N4O3/c1-10-7-15(20-24-10)19-16(22)12-4-3-11-8-14-17(23)18-5-2-6-21(14)13(11)9-12/h3-4,7-9H,2,5-6H2,1H3,(H,18,23)(H,19,20,22)
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n/an/a 30n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184159
PNG
(US9150577, 3)
Show SMILES CC(C)(C)c1cc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3c2)sn1
Show InChI InChI=1S/C20H22N4O2S/c1-20(2,3)16-11-17(27-23-16)22-18(25)13-6-5-12-9-15-19(26)21-7-4-8-24(15)14(12)10-13/h5-6,9-11H,4,7-8H2,1-3H3,(H,21,26)(H,22,25)
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n/an/a 240n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM50361873
PNG
(CHEMBL1938782 | US9150577, 4)
Show SMILES Clc1ccc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3c2)cc1
Show InChI InChI=1S/C19H16ClN3O2/c20-14-4-6-15(7-5-14)22-18(24)13-3-2-12-10-17-19(25)21-8-1-9-23(17)16(12)11-13/h2-7,10-11H,1,8-9H2,(H,21,25)(H,22,24)
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n/an/a 190n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM50361849
PNG
(CHEMBL1938800 | US9150577, 5)
Show SMILES O=C(Nc1ccc2ccccc2n1)c1ccc2cc3C(=O)NCCCn3c2c1
Show InChI InChI=1S/C22H18N4O2/c27-21(25-20-9-8-14-4-1-2-5-17(14)24-20)16-7-6-15-12-19-22(28)23-10-3-11-26(19)18(15)13-16/h1-2,4-9,12-13H,3,10-11H2,(H,23,28)(H,24,25,27)
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n/an/a 70n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184160
PNG
(US9150577, 6)
Show SMILES O=C(Nc1cccc(c1)C#N)c1ccc2cc3C(=O)NCCCn3c2c1
Show InChI InChI=1S/C20H16N4O2/c21-12-13-3-1-4-16(9-13)23-19(25)15-6-5-14-10-18-20(26)22-7-2-8-24(18)17(14)11-15/h1,3-6,9-11H,2,7-8H2,(H,22,26)(H,23,25)
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n/an/a 140n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184161
PNG
(US9150577, 7)
Show SMILES O=C(Nc1cccc(c1)N1CCOCC1)c1ccc2cc3C(=O)NCCCn3c2c1
Show InChI InChI=1S/C23H24N4O3/c28-22(25-18-3-1-4-19(15-18)26-9-11-30-12-10-26)17-6-5-16-13-21-23(29)24-7-2-8-27(21)20(16)14-17/h1,3-6,13-15H,2,7-12H2,(H,24,29)(H,25,28)
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n/an/a 60n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184162
PNG
(US9150577, 8)
Show SMILES O=C(Nc1cccc(Oc2ccccc2)c1)c1ccc2cc3C(=O)NCCCn3c2c1
Show InChI InChI=1S/C25H21N3O3/c29-24(27-19-6-4-9-21(16-19)31-20-7-2-1-3-8-20)18-11-10-17-14-23-25(30)26-12-5-13-28(23)22(17)15-18/h1-4,6-11,14-16H,5,12-13H2,(H,26,30)(H,27,29)
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n/an/a 900n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM50361855
PNG
(CHEMBL1938768 | US9150577, 9)
Show SMILES CC1(C)CNC(=O)c2cc3ccc(cc3n2C1)C(=O)Nc1cccnc1
Show InChI InChI=1S/C20H20N4O2/c1-20(2)11-22-19(26)17-8-13-5-6-14(9-16(13)24(17)12-20)18(25)23-15-4-3-7-21-10-15/h3-10H,11-12H2,1-2H3,(H,22,26)(H,23,25)
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n/an/a 4.60E+3n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM50361835
PNG
(CHEMBL1938765 | US9150577, 10)
Show SMILES CC1CCNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1cccnc1
Show InChI InChI=1S/C19H18N4O2/c1-12-6-8-21-19(25)17-9-13-4-5-14(10-16(13)23(12)17)18(24)22-15-3-2-7-20-11-15/h2-5,7,9-12H,6,8H2,1H3,(H,21,25)(H,22,24)
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n/an/a 41n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM50361869
PNG
(CHEMBL1938795 | US9150577, 11)
Show SMILES Cn1ccc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3c2)n1
Show InChI InChI=1S/C17H17N5O2/c1-21-8-5-15(20-21)19-16(23)12-4-3-11-9-14-17(24)18-6-2-7-22(14)13(11)10-12/h3-5,8-10H,2,6-7H2,1H3,(H,18,24)(H,19,20,23)
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n/an/a 540n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184163
PNG
(US9150577, 12)
Show SMILES Fc1ccc(Cn2ccc(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)n2)cc1
Show InChI InChI=1S/C23H20FN5O2/c24-18-6-2-15(3-7-18)14-28-11-8-21(27-28)26-22(30)17-5-4-16-12-20-23(31)25-9-1-10-29(20)19(16)13-17/h2-8,11-13H,1,9-10,14H2,(H,25,31)(H,26,27,30)
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n/an/a 220n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184164
PNG
(US9150577, 13)
Show SMILES CC(C)n1ccc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3c2)n1
Show InChI InChI=1S/C19H21N5O2/c1-12(2)24-9-6-17(22-24)21-18(25)14-5-4-13-10-16-19(26)20-7-3-8-23(16)15(13)11-14/h4-6,9-12H,3,7-8H2,1-2H3,(H,20,26)(H,21,22,25)
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n/an/a 1.60E+3n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184165
PNG
(US9150577, 14)
Show SMILES O=C(Nc1ccn(n1)-c1ccccc1)c1ccc2cc3C(=O)NCCCn3c2c1
Show InChI InChI=1S/C22H19N5O2/c28-21(24-20-9-12-27(25-20)17-5-2-1-3-6-17)16-8-7-15-13-19-22(29)23-10-4-11-26(19)18(15)14-16/h1-3,5-9,12-14H,4,10-11H2,(H,23,29)(H,24,25,28)
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n/an/a 108n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM50361846
PNG
(CHEMBL1938794 | US9150577, 15)
Show SMILES O=C(Nc1cn[nH]c1)c1ccc2cc3C(=O)NCCCn3c2c1
Show InChI InChI=1S/C16H15N5O2/c22-15(20-12-8-18-19-9-12)11-3-2-10-6-14-16(23)17-4-1-5-21(14)13(10)7-11/h2-3,6-9H,1,4-5H2,(H,17,23)(H,18,19)(H,20,22)
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n/an/a 43n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184166
PNG
(US9150577, 16)
Show SMILES CC1(C)CNC(=O)c2cc3ccc(cc3n2C1)C(=O)Nc1cn[nH]c1
Show InChI InChI=1S/C18H19N5O2/c1-18(2)9-19-17(25)15-5-11-3-4-12(6-14(11)23(15)10-18)16(24)22-13-7-20-21-8-13/h3-8H,9-10H2,1-2H3,(H,19,25)(H,20,21)(H,22,24)
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n/an/a 2.50E+3n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184167
PNG
(US9150577, 17)
Show SMILES CC1CNC(=O)c2cc3ccc(cc3n2C1)C(=O)Nc1cn[nH]c1
Show InChI InChI=1S/C17H17N5O2/c1-10-6-18-17(24)15-4-11-2-3-12(5-14(11)22(15)9-10)16(23)21-13-7-19-20-8-13/h2-5,7-8,10H,6,9H2,1H3,(H,18,24)(H,19,20)(H,21,23)
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n/an/a 145n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184168
PNG
(US9150577, 18)
Show SMILES CC(C)n1ncc2cc(NC(=O)c3ccc4cc5C(=O)N[C@H](C)[C@H](C)n5c4c3)cnc12
Show InChI InChI=1S/C23H24N6O2/c1-12(2)29-21-17(10-25-29)7-18(11-24-21)27-22(30)16-6-5-15-8-20-23(31)26-13(3)14(4)28(20)19(15)9-16/h5-14H,1-4H3,(H,26,31)(H,27,30)/t13-,14+/m1/s1
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n/an/a 8.10n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM50361848
PNG
(CHEMBL1938799 | US9150577, 19)
Show SMILES CC(C)n1ncc2cc(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)cnc12
Show InChI InChI=1S/C22H22N6O2/c1-13(2)28-20-16(11-25-28)8-17(12-24-20)26-21(29)15-5-4-14-9-19-22(30)23-6-3-7-27(19)18(14)10-15/h4-5,8-13H,3,6-7H2,1-2H3,(H,23,30)(H,26,29)
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n/an/a 53n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184169
PNG
(US9150577, 20)
Show SMILES Cn1ncc2cc(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)cnc12
Show InChI InChI=1S/C20H18N6O2/c1-25-18-14(10-23-25)7-15(11-22-18)24-19(27)13-4-3-12-8-17-20(28)21-5-2-6-26(17)16(12)9-13/h3-4,7-11H,2,5-6H2,1H3,(H,21,28)(H,24,27)
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n/an/a 87n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184170
PNG
(US9150577, 21)
Show SMILES C[C@H]1NC(=O)c2cc3ccc(cc3n2[C@H]1C)C(=O)Nc1cnn(C)c1
Show InChI InChI=1S/C18H19N5O2/c1-10-11(2)23-15-7-13(17(24)21-14-8-19-22(3)9-14)5-4-12(15)6-16(23)18(25)20-10/h4-11H,1-3H3,(H,20,25)(H,21,24)/t10-,11+/m1/s1
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n/an/a 4.30n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184171
PNG
(US9150577, 22)
Show SMILES CC1CNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1cnn(C)c1
Show InChI InChI=1S/C17H17N5O2/c1-10-7-18-17(24)15-5-11-3-4-12(6-14(11)22(10)15)16(23)20-13-8-19-21(2)9-13/h3-6,8-10H,7H2,1-2H3,(H,18,24)(H,20,23)
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n/an/a 5.10n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM50360288
PNG
(CHEMBL1933148 | US9150577, 23)
Show SMILES Cn1cc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3c2)cn1
Show InChI InChI=1S/C17H17N5O2/c1-21-10-13(9-19-21)20-16(23)12-4-3-11-7-15-17(24)18-5-2-6-22(15)14(11)8-12/h3-4,7-10H,2,5-6H2,1H3,(H,18,24)(H,20,23)
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n/an/a 11n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184172
PNG
(US9150577, 24)
Show SMILES Cn1cc(NC(=O)c2ccc3cc4C(=O)NCC5(CCC5)Cn4c3c2)cn1
Show InChI InChI=1S/C20H21N5O2/c1-24-10-15(9-22-24)23-18(26)14-4-3-13-7-17-19(27)21-11-20(5-2-6-20)12-25(17)16(13)8-14/h3-4,7-10H,2,5-6,11-12H2,1H3,(H,21,27)(H,23,26)
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n/an/a 320n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184173
PNG
(US9150577, 25)
Show SMILES CC(C)n1cc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3c2)cn1
Show InChI InChI=1S/C19H21N5O2/c1-12(2)24-11-15(10-21-24)22-18(25)14-5-4-13-8-17-19(26)20-6-3-7-23(17)16(13)9-14/h4-5,8-12H,3,6-7H2,1-2H3,(H,20,26)(H,22,25)
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n/an/a 14n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184174
PNG
(US9150577, 26)
Show SMILES O=C(Nc1cnn(c1)C1CCOC1)c1ccc2cc3C(=O)NCCCn3c2c1
Show InChI InChI=1S/C20H21N5O3/c26-19(23-15-10-22-25(11-15)16-4-7-28-12-16)14-3-2-13-8-18-20(27)21-5-1-6-24(18)17(13)9-14/h2-3,8-11,16H,1,4-7,12H2,(H,21,27)(H,23,26)
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n/an/a 27n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184175
PNG
(US9150577, 27)
Show SMILES O=C(Nc1cnn(c1)C1CCOCC1)c1ccc2cc3C(=O)NCCCn3c2c1
Show InChI InChI=1S/C21H23N5O3/c27-20(24-16-12-23-26(13-16)17-4-8-29-9-5-17)15-3-2-14-10-19-21(28)22-6-1-7-25(19)18(14)11-15/h2-3,10-13,17H,1,4-9H2,(H,22,28)(H,24,27)
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n/an/a 46n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184176
PNG
(US9150577, 28)
Show SMILES Cc1cc(C)cc(Cn2cc(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)cn2)c1
Show InChI InChI=1S/C25H25N5O2/c1-16-8-17(2)10-18(9-16)14-29-15-21(13-27-29)28-24(31)20-5-4-19-11-23-25(32)26-6-3-7-30(23)22(19)12-20/h4-5,8-13,15H,3,6-7,14H2,1-2H3,(H,26,32)(H,28,31)
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n/an/a 1.90n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184177
PNG
(BDBM184272 | US9150577, 29)
Show SMILES C[C@H]1NC(=O)c2cc3ccc(cc3n2[C@H]1C)C(=O)Nc1cnn(Cc2ccccc2)c1
Show InChI InChI=1S/C24H23N5O2/c1-15-16(2)29-21-11-19(9-8-18(21)10-22(29)24(31)26-15)23(30)27-20-12-25-28(14-20)13-17-6-4-3-5-7-17/h3-12,14-16H,13H2,1-2H3,(H,26,31)(H,27,30)/t15-,16+/m1/s1
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n/an/a 1.90n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184178
PNG
(US9150577, 30)
Show SMILES C[C@@H]1NC(=O)c2cc3ccc(cc3n2[C@H]1C)C(=O)Nc1cnn(Cc2ccccc2)c1
Show InChI InChI=1S/C24H23N5O2/c1-15-16(2)29-21-11-19(9-8-18(21)10-22(29)24(31)26-15)23(30)27-20-12-25-28(14-20)13-17-6-4-3-5-7-17/h3-12,14-16H,13H2,1-2H3,(H,26,31)(H,27,30)/t15-,16-/m0/s1
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n/an/a 10n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184179
PNG
(US9150577, 31)
Show SMILES O=C(Nc1cnn(Cc2ccccc2)c1)c1ccc2cc3C(=O)NCC4(CCOCC4)Cn3c2c1
Show InChI InChI=1S/C27H27N5O3/c33-25(30-22-14-29-31(16-22)15-19-4-2-1-3-5-19)21-7-6-20-12-24-26(34)28-17-27(8-10-35-11-9-27)18-32(24)23(20)13-21/h1-7,12-14,16H,8-11,15,17-18H2,(H,28,34)(H,30,33)
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n/an/a 900n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184180
PNG
(US9150577, 32)
Show SMILES O=C(Nc1cnn(Cc2ccccc2)c1)c1ccc2cc3C(=O)NCCCn3c2c1
Show InChI InChI=1S/C23H21N5O2/c29-22(26-19-13-25-27(15-19)14-16-5-2-1-3-6-16)18-8-7-17-11-21-23(30)24-9-4-10-28(21)20(17)12-18/h1-3,5-8,11-13,15H,4,9-10,14H2,(H,24,30)(H,26,29)
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n/an/a 4n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM50360289
PNG
(CHEMBL1933149 | US9150577, 33)
Show SMILES O=C(Nc1cnn(CC2CCCCC2)c1)c1ccc2cc3C(=O)NCCCn3c2c1
Show InChI InChI=1S/C23H27N5O2/c29-22(26-19-13-25-27(15-19)14-16-5-2-1-3-6-16)18-8-7-17-11-21-23(30)24-9-4-10-28(21)20(17)12-18/h7-8,11-13,15-16H,1-6,9-10,14H2,(H,24,30)(H,26,29)
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n/an/a 7.40n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184181
PNG
(US9150577, 34)
Show SMILES Cc1ccccc1Cn1cc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3c2)cn1
Show InChI InChI=1S/C24H23N5O2/c1-16-5-2-3-6-19(16)14-28-15-20(13-26-28)27-23(30)18-8-7-17-11-22-24(31)25-9-4-10-29(22)21(17)12-18/h2-3,5-8,11-13,15H,4,9-10,14H2,1H3,(H,25,31)(H,27,30)
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n/an/a 7.90n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184182
PNG
(US9150577, 35)
Show SMILES CC(C)CCn1cc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3c2)cn1
Show InChI InChI=1S/C21H25N5O2/c1-14(2)6-9-25-13-17(12-23-25)24-20(27)16-5-4-15-10-19-21(28)22-7-3-8-26(19)18(15)11-16/h4-5,10-14H,3,6-9H2,1-2H3,(H,22,28)(H,24,27)
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n/an/a 11n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184183
PNG
(US9150577, 36)
Show SMILES CN(C)CCCn1cc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3c2)cn1
Show InChI InChI=1S/C21H26N6O2/c1-25(2)8-4-9-26-14-17(13-23-26)24-20(28)16-6-5-15-11-19-21(29)22-7-3-10-27(19)18(15)12-16/h5-6,11-14H,3-4,7-10H2,1-2H3,(H,22,29)(H,24,28)
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n/an/a 84n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184184
PNG
(US9150577, 37)
Show SMILES O=C(Nc1cnn(CCN2CCOCC2)c1)c1ccc2cc3C(=O)NCCCn3c2c1
Show InChI InChI=1S/C22H26N6O3/c29-21(25-18-14-24-27(15-18)7-6-26-8-10-31-11-9-26)17-3-2-16-12-20-22(30)23-4-1-5-28(20)19(16)13-17/h2-3,12-15H,1,4-11H2,(H,23,30)(H,25,29)
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n/an/a 84n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184185
PNG
(US9150577, 38)
Show SMILES COCCn1cc(NC(=O)c2ccc3cc4C(=O)NCCCn4c3c2)cn1
Show InChI InChI=1S/C19H21N5O3/c1-27-8-7-23-12-15(11-21-23)22-18(25)14-4-3-13-9-17-19(26)20-5-2-6-24(17)16(13)10-14/h3-4,9-12H,2,5-8H2,1H3,(H,20,26)(H,22,25)
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n/an/a 19n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184186
PNG
(US9150577, 39)
Show SMILES Cc1ccc2[nH]c(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)nc2c1
Show InChI InChI=1S/C21H19N5O2/c1-12-3-6-15-16(9-12)24-21(23-15)25-19(27)14-5-4-13-10-18-20(28)22-7-2-8-26(18)17(13)11-14/h3-6,9-11H,2,7-8H2,1H3,(H,22,28)(H2,23,24,25,27)
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n/an/a 3n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184187
PNG
(US9150577, 40)
Show SMILES CCn1c(NC(=O)c2ccc3cc4C(=O)NCCCn4c3c2)nc2cc(C)ccc12
Show InChI InChI=1S/C23H23N5O2/c1-3-27-18-8-5-14(2)11-17(18)25-23(27)26-21(29)16-7-6-15-12-20-22(30)24-9-4-10-28(20)19(15)13-16/h5-8,11-13H,3-4,9-10H2,1-2H3,(H,24,30)(H,25,26,29)
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n/an/a 4.80n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184188
PNG
(US9150577, 41)
Show SMILES O=C(Nc1nc2cc(ccc2[nH]1)C#N)c1ccc2cc3C(=O)NCCCn3c2c1
Show InChI InChI=1S/C21H16N6O2/c22-11-12-2-5-15-16(8-12)25-21(24-15)26-19(28)14-4-3-13-9-18-20(29)23-6-1-7-27(18)17(13)10-14/h2-5,8-10H,1,6-7H2,(H,23,29)(H2,24,25,26,28)
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n/an/a 4.90n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184189
PNG
(US9150577, 42)
Show SMILES CC(C)c1ccc2[nH]c(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)nc2c1
Show InChI InChI=1S/C23H23N5O2/c1-13(2)14-6-7-17-18(10-14)26-23(25-17)27-21(29)16-5-4-15-11-20-22(30)24-8-3-9-28(20)19(15)12-16/h4-7,10-13H,3,8-9H2,1-2H3,(H,24,30)(H2,25,26,27,29)
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n/an/a 6.20n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184190
PNG
(US9150577, 43)
Show SMILES FC(F)(F)c1ccc2[nH]c(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)nc2c1
Show InChI InChI=1S/C21H16F3N5O2/c22-21(23,24)13-4-5-14-15(10-13)27-20(26-14)28-18(30)12-3-2-11-8-17-19(31)25-6-1-7-29(17)16(11)9-12/h2-5,8-10H,1,6-7H2,(H,25,31)(H2,26,27,28,30)
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n/an/a 24n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184191
PNG
(US9150577, 44)
Show SMILES CN1CCN(CC1)c1ccc2[nH]c(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)nc2c1
Show InChI InChI=1S/C25H27N7O2/c1-30-9-11-31(12-10-30)18-5-6-19-20(15-18)28-25(27-19)29-23(33)17-4-3-16-13-22-24(34)26-7-2-8-32(22)21(16)14-17/h3-6,13-15H,2,7-12H2,1H3,(H,26,34)(H2,27,28,29,33)
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n/an/a 2.60n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184192
PNG
(US9150577, 45)
Show SMILES CCCS(=O)(=O)c1ccc2[nH]c(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)nc2c1
Show InChI InChI=1S/C23H25N5O4S/c1-2-10-33(31,32)16-6-7-17-18(13-16)26-23(25-17)27-21(29)15-5-4-14-11-20-22(30)24-8-3-9-28(20)19(14)12-15/h4-7,11-13,33H,2-3,8-10H2,1H3,(H,24,30)(H,31,32)(H2,25,26,27,29)
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n/an/a 3.60n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184193
PNG
(US9150577, 46)
Show SMILES Clc1cc(CN2CCOCC2)c2[nH]c(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)nc2c1
Show InChI InChI=1S/C25H25ClN6O3/c26-18-10-17(14-31-6-8-35-9-7-31)22-19(13-18)28-25(29-22)30-23(33)16-3-2-15-11-21-24(34)27-4-1-5-32(21)20(15)12-16/h2-3,10-13H,1,4-9,14H2,(H,27,34)(H2,28,29,30,33)
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n/an/a 8.70n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184194
PNG
(US9150577, 47)
Show SMILES Clc1ccc2[nH]c(NC(=O)c3ccc4cc5C(=O)NCCCn5c4c3)nc2c1
Show InChI InChI=1S/C20H16ClN5O2/c21-13-4-5-14-15(10-13)24-20(23-14)25-18(27)12-3-2-11-8-17-19(28)22-6-1-7-26(17)16(11)9-12/h2-5,8-10H,1,6-7H2,(H,22,28)(H2,23,24,25,27)
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n/an/a 8n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184195
PNG
(US9150577, 48)
Show SMILES CC1CCNC(=O)c2cc3ccc(cc3n12)C(=O)Nc1nc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C21H18ClN5O2/c1-11-6-7-23-20(29)18-8-12-2-3-13(9-17(12)27(11)18)19(28)26-21-24-15-5-4-14(22)10-16(15)25-21/h2-5,8-11H,6-7H2,1H3,(H,23,29)(H2,24,25,26,28)
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n/an/a 2.5n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
Ribosomal protein S6 kinase alpha 2


(Homo sapiens (human))
BDBM184196
PNG
(US9150577, 49)
Show SMILES Cn1c(NC(=O)c2ccc3cc4C(=O)NCCCn4c3c2)nc2cc(Cl)ccc12
Show InChI InChI=1S/C21H18ClN5O2/c1-26-16-6-5-14(22)11-15(16)24-21(26)25-19(28)13-4-3-12-9-18-20(29)23-7-2-8-27(18)17(12)10-13/h3-6,9-11H,2,7-8H2,1H3,(H,23,29)(H,24,25,28)
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n/an/a 26n/an/an/an/a7.5n/a



Boehringer Ingelheim International GmbH

US Patent


Assay Description
Human RSK2 protein, purchased from Invitrogen, is used to measure kinase activity utilizing Kinase Glo Plus (Promega) a homogeneous assay technology,...


US Patent US9150577 (2015)


BindingDB Entry DOI: 10.7270/Q2GB22V6
More data for this
Ligand-Target Pair
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