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Found 148 Enz. Inhib. hit(s) with Target = 'Sarcoplasmic/endoplasmic reticulum calcium ATPase 1'
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34111(BMC171353 Compound 6b | hydroquinone derivative, 2...)
Affinity DataIC50:  1.20E+5nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34112(hydroquinone derivative, 2b)
Affinity DataIC50:  5.70E+3nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34140(2,2,2-methanetriyltris(4-tert-butylphenol), 11)
Affinity DataIC50:  2.13E+4nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34139(4-(7-methyloctyl)phenol, 10)
Affinity DataIC50:  1.72E+4nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34138(4,5-dibenzylbenzene-1,2-diol, 9)
Affinity DataIC50:  2.38E+4nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34137(4,4-butane-2,3-diyldiphenol, 8)
Affinity DataIC50:  2.83E+4nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34136(1,1-methanediyldinaphthalen-2-ol, 7b)
Affinity DataIC50:  1.50E+4nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34135(1-(naphthalen-1-ylmethyl)naphthalen-2-ol, 7a)
Affinity DataIC50:  2.73E+4nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34111(BMC171353 Compound 6b | hydroquinone derivative, 2...)
Affinity DataIC50:  2.02E+4nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34134(2,5-dibenzylbenzene-1,4-diol, 6a)
Affinity DataIC50:  9.40E+3nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34133(4,4-butane-2,2-diylbis(2-methylphenol), 5c)
Affinity DataIC50:  3.93E+4nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34132(4-(1,1-diphenylethyl)phenol, 5b)
Affinity DataIC50:  4.97E+4nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34113(hydroquinone derivative, 2c)
Affinity DataIC50:  7.30E+3nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34114(hydroquinone derivative, 2d)
Affinity DataIC50:  5.20E+4nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34115(hydroquinone derivative, 3a)
Affinity DataIC50:  3.80E+3nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34116(hydroquinone derivative, 3b)
Affinity DataIC50:  1.20E+4nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34117(hydroquinone derivative, 5a)
Affinity DataIC50:  340nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34118(hydroquinone derivative, 5b)
Affinity DataIC50:  610nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34119(hydroquinone derivative, 5c)
Affinity DataIC50:  3.30E+3nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34120(hydroquinone derivative, 6)
Affinity DataIC50:  6.00E+3nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34121(hydroquinone derivative, 8b)
Affinity DataIC50:  2.90E+4nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34122(hydroquinone derivative, 9)
Affinity DataIC50:  2.60E+3nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34123(phenol derivative, 1a)
Affinity DataIC50:  1.88E+4nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34124(hydroquinone derivative, 1b)
Affinity DataIC50:  1.15E+4nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34125(2-Phenylhydroquinone, 7 | hydroquinone derivative,...)
Affinity DataIC50:  2.29E+3nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34126(US9688816, 1 | bis(2,6-dimethylphenol), 2)
Affinity DataIC50:  1.95E+4nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34127(6-tert-butyl-2,3-dihydro-1H-inden-5-ol, 3)
Affinity DataIC50:  2.81E+4nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34128(2,4-di-tert-butyl-6-(1-phenylethyl)phenol, 4a)
Affinity DataIC50:  3.38E+4nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34129(2,4-di-tert-butyl-6-[1-(4-methoxyphenyl)ethyl]phen...)
Affinity DataIC50:  3.53E+4nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34130(2,6-di-tert-butyl-4-[1-(4-methoxyphenyl)ethyl]phen...)
Affinity DataIC50:  4.54E+4nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM34131(2,2-methanediylbis(4-tert-butylphenol), 5a)
Affinity DataIC50:  1.18E+4nMpH: 7.3 T: 2°CAssay Description:Inhibitory potencies of compounds were determined in a coupled ATPase activity assay using SERCA microsomes at 14 different inhibitor concentrations....More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50035612(CHEMBL96926 | OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4...)
Affinity DataKi:  0.100nMAssay Description:Inhibition of SERCA1a (unknown origin) ATPase activityMore data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM50527063(CHEMBL4534285)
Affinity DataKi:  11nMAssay Description:Inhibition of rabbit skeletal muscle microsomes SERCA1aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM50453612(CHEMBL4216774)
Affinity DataKi:  17nMAssay Description:Inhibition of rabbit skeletal muscle microsomes SERCA1aMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50453612(CHEMBL4216774)
Affinity DataKi:  17nMAssay Description:Inhibition of SERCA1a (unknown origin) ATPase activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM50527071(CHEMBL4514624)
Affinity DataKi:  18nMAssay Description:Inhibition of rabbit skeletal muscle microsomes SERCA1aMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM50453611(CHEMBL4207081)
Affinity DataKi:  19nMAssay Description:Inhibition of rabbit skeletal muscle microsomes SERCA1aMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
LigandPNGBDBM50453611(CHEMBL4207081)
Affinity DataKi:  19nMAssay Description:Inhibition of SERCA1a (unknown origin) ATPase activityMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sidPDB
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM50527070(CHEMBL4467779)
Affinity DataKi:  1.00E+3nMAssay Description:Inhibition of rabbit skeletal muscle microsomes SERCA1a by enzyme-coupled methodMore data for this Ligand-Target Pair
Ligand InfoPC cidPC sid
In DepthDetails ArticlePubMed
LigandPNGBDBM50453613(Alpha-Cyclopiazonic Acid | CHEBI:22450 | Cyclopiaz...)
Affinity DataKi:  1.80E+3nMAssay Description:Inhibition of SERCA1a (unknown origin) ATPase activityMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM50140172(CHEBI:3962 | CHEMBL140 | Curcumin | US9409845, Tab...)
Affinity DataKi:  5.80E+3nMAssay Description:Inhibition of rabbit SERCA1b expressed in COS7 cells microsomal membranes preincubated for 10 mins followed by addition of ATP and measured after 40 ...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM31774(CHEMBL104 | Canesten | Clotrimazole | Lotrimin | M...)
Affinity DataKi:  3.50E+4nMAssay Description:Inhibition of rabbit skeletal muscle microsomes SERCA1aMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50165366(CHEMBL191927 | Pentanedioic acid mono-((2S,3aR,4S,...)
Affinity DataIC50:  19.8nMAssay Description:Inhibitory activity against sarco- endoplasmic reticulum calcium-ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50165367(CHEMBL362947 | Octanoic acid (2S,3aR,4S,6S,6aR,7S,...)
Affinity DataIC50:  9.04E+3nMAssay Description:Inhibitory activity against sarco- endoplasmic reticulum calcium-ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50165368(CHEMBL191633 | Dodecanedioic acid mono-((2S,3aR,4S...)
Affinity DataIC50:  2.08nMAssay Description:Inhibitory activity against sarco- endoplasmic reticulum calcium-ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
LigandPNGBDBM50165369(12-(4-Amino-4-carboxy-butyrylamino)-dodecanoic aci...)
Affinity DataIC50:  1.20nMAssay Description:Inhibitory activity against sarco- endoplasmic reticulum calcium-ATPaseMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Rattus norvegicus)
Albert-Ludwigs-University Of Freiburg

Curated by ChEMBL
LigandPNGBDBM50409816(ABAMECTIN)
Affinity DataIC50:  1.69E+4nMAssay Description:Inhibition of Wistar rat EDL muscle SERCA1a after 1 hrMore data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM50035612(CHEMBL96926 | OCTANOIC ACID [3S-[3ALPHA, 3ABETA, 4...)
Affinity DataKd:  0.200nMAssay Description:Binding affinity to rabbit skeletal muscle SERCA1a preincubated for 5 mins followed by Mg-ATP addition measured over 6 mins by spectrophotometric ana...More data for this Ligand-Target Pair
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM50097525(CHEMBL3586099)
Affinity DataKd: >1.00E+5nMAssay Description:Binding affinity to rabbit skeletal muscle SERCA1a preincubated for 5 mins followed by Mg-ATP addition measured over 6 mins by spectrophotometric ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
TargetSarcoplasmic/endoplasmic reticulum calcium ATPase 1(Oryctolagus cuniculus)
Northern Kentucky University

LigandPNGBDBM50097535(CHEMBL3125414)
Affinity DataKd:  3.15E+4nMAssay Description:Binding affinity to rabbit skeletal muscle SERCA1a preincubated for 5 mins followed by Mg-ATP addition measured over 6 mins by spectrophotometric ana...More data for this Ligand-Target Pair
In DepthDetails ArticlePubMed
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