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Compile Data Set for Download or QSAR

Found 433 hits Enz. Inhib. hit(s) with Target = 'Sentrin-specific protease 1 (SENP1)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM103831
PNG
(SPI-06)
Show SMILES Cc1ccccc1\N=N\c1cc(c2ccccc2c1N)S(O)(=O)=O
Show InChI InChI=1S/C17H15N3O3S/c1-11-6-2-5-9-14(11)19-20-15-10-16(24(21,22)23)12-7-3-4-8-13(12)17(15)18/h2-10H,18H2,1H3,(H,21,22,23)/b20-19+
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n/an/a>6.00E+7n/an/an/an/a7.4n/a



Beckman Research Institute of the City of Hope



Assay Description
Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...


ACS Chem Biol 8: 1435-41 (2013)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2KH0KZN
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM103834
PNG
(SPI-09)
Show SMILES Nc1ccc2cc(cc(c2c1\N=N\c1ccc(cc1)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O
Show InChI InChI=1S/C16H13N3O9S3/c17-13-6-1-9-7-12(30(23,24)25)8-14(31(26,27)28)15(9)16(13)19-18-10-2-4-11(5-3-10)29(20,21)22/h1-8H,17H2,(H,20,21,22)(H,23,24,25)(H,26,27,28)/b19-18+
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n/an/a>6.00E+4n/an/an/an/a7.4n/a



Beckman Research Institute of the City of Hope



Assay Description
Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...


ACS Chem Biol 8: 1435-41 (2013)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2KH0KZN
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM103833
PNG
(SPI-08)
Show SMILES Nc1c(cc(c2ccccc12)S([O-])(=O)=O)\N=N\c1ccccc1
Show InChI InChI=1S/C16H13N3O3S/c17-16-13-9-5-4-8-12(13)15(23(20,21)22)10-14(16)19-18-11-6-2-1-3-7-11/h1-10H,17H2,(H,20,21,22)/p-1/b19-18+
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n/an/a>6.00E+4n/an/an/an/a7.4n/a



Beckman Research Institute of the City of Hope



Assay Description
Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...


ACS Chem Biol 8: 1435-41 (2013)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2KH0KZN
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM103832
PNG
(SPI-07)
Show SMILES Cc1cc(N)ccc1\N=N\c1cc(c2cccc(c2c1)S([O-])(=O)=O)S([O-])(=O)=O
Show InChI InChI=1S/C17H15N3O6S2/c1-10-7-11(18)5-6-15(10)20-19-12-8-14-13(17(9-12)28(24,25)26)3-2-4-16(14)27(21,22)23/h2-9H,18H2,1H3,(H,21,22,23)(H,24,25,26)/p-2/b20-19+
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n/an/a 1.75E+4n/an/an/an/a7.4n/a



Beckman Research Institute of the City of Hope



Assay Description
Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...


ACS Chem Biol 8: 1435-41 (2013)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2KH0KZN
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM103831
PNG
(SPI-06)
Show SMILES Cc1ccccc1\N=N\c1cc(c2ccccc2c1N)S(O)(=O)=O
Show InChI InChI=1S/C17H15N3O3S/c1-11-6-2-5-9-14(11)19-20-15-10-16(24(21,22)23)12-7-3-4-8-13(12)17(15)18/h2-10H,18H2,1H3,(H,21,22,23)/b20-19+
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n/an/a 4.32E+4n/an/an/an/a7.4n/a



Beckman Research Institute of the City of Hope



Assay Description
Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...


ACS Chem Biol 8: 1435-41 (2013)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2KH0KZN
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM103830
PNG
(SPI-05)
Show SMILES Nc1ccc(\N=N\c2ccc(\C=C\c3ccc(cc3S(O)(=O)=O)\N=N\c3ccc(N)c4ccccc34)c(c2)S(O)(=O)=O)c2ccccc12
Show InChI InChI=1S/C34H26N6O6S2/c35-29-15-17-31(27-7-3-1-5-25(27)29)39-37-23-13-11-21(33(19-23)47(41,42)43)9-10-22-12-14-24(20-34(22)48(44,45)46)38-40-32-18-16-30(36)26-6-2-4-8-28(26)32/h1-20H,35-36H2,(H,41,42,43)(H,44,45,46)/b10-9+,39-37+,40-38+
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n/an/a 7.50E+3n/an/an/an/a7.4n/a



Beckman Research Institute of the City of Hope



Assay Description
Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...


ACS Chem Biol 8: 1435-41 (2013)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2KH0KZN
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM103829
PNG
(SPI-04)
Show SMILES Nc1ccc(\N=N\c2ccc(\C=C\c3ccc(cc3S(O)(=O)=O)\N=N\c3ccc(N)c4ccc(cc34)S([O-])(=O)=O)c(c2)S(O)(=O)=O)c2cc(ccc12)S(O)(=O)=O
Show InChI InChI=1S/C34H26N6O12S4/c35-29-11-13-31(27-17-23(53(41,42)43)7-9-25(27)29)39-37-21-5-3-19(33(15-21)55(47,48)49)1-2-20-4-6-22(16-34(20)56(50,51)52)38-40-32-14-12-30(36)26-10-8-24(18-28(26)32)54(44,45)46/h1-18H,35-36H2,(H,41,42,43)(H,44,45,46)(H,47,48,49)(H,50,51,52)/p-1/b2-1+,39-37+,40-38+
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n/an/a 2.32E+3n/an/an/an/a7.4n/a



Beckman Research Institute of the City of Hope



Assay Description
Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...


ACS Chem Biol 8: 1435-41 (2013)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2KH0KZN
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM103828
PNG
(SPI-03)
Show SMILES Cc1cc(ccc1-c1ccc(cc1C)\N=N\c1cc(c2ccccc2c1N)S(O)(=O)=O)\N=N\c1cc(c2ccccc2c1N)S(O)(=O)=O
Show InChI InChI=1S/C34H28N6O6S2/c1-19-15-21(37-39-29-17-31(47(41,42)43)25-7-3-5-9-27(25)33(29)35)11-13-23(19)24-14-12-22(16-20(24)2)38-40-30-18-32(48(44,45)46)26-8-4-6-10-28(26)34(30)36/h3-18H,35-36H2,1-2H3,(H,41,42,43)(H,44,45,46)/b39-37+,40-38+
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n/an/a 1.86E+3n/an/an/an/a7.4n/a



Beckman Research Institute of the City of Hope



Assay Description
Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...


ACS Chem Biol 8: 1435-41 (2013)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2KH0KZN
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM103826
PNG
(SPI-01)
Show SMILES Nc1ccc2ccccc2c1\N=N\c1ccc(\C=C\c2ccc(cc2S(O)(=O)=O)\N=N\c2c(N)ccc3ccccc23)c(c1)S(O)(=O)=O
Show InChI InChI=1S/C34H26N6O6S2/c35-29-17-13-21-5-1-3-7-27(21)33(29)39-37-25-15-11-23(31(19-25)47(41,42)43)9-10-24-12-16-26(20-32(24)48(44,45)46)38-40-34-28-8-4-2-6-22(28)14-18-30(34)36/h1-20H,35-36H2,(H,41,42,43)(H,44,45,46)/b10-9+,39-37+,40-38+
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n/an/a 3.28E+4n/an/an/an/a7.4n/a



Beckman Research Institute of the City of Hope



Assay Description
Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...


ACS Chem Biol 8: 1435-41 (2013)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2KH0KZN
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM103827
PNG
(SPI-02)
Show SMILES Cc1cc(ccc1\N=N\c1c(N)ccc2cc(ccc12)S(O)(=O)=O)-c1ccc(\N=N\c2c(N)c(cc3cc(ccc23)S(O)(=O)=O)S(O)(=O)=O)c(C)c1
Show InChI InChI=1S/C34H28N6O9S3/c1-18-13-20(4-11-29(18)37-39-33-26-8-6-24(50(41,42)43)15-22(26)3-10-28(33)35)21-5-12-30(19(2)14-21)38-40-34-27-9-7-25(51(44,45)46)16-23(27)17-31(32(34)36)52(47,48)49/h3-17H,35-36H2,1-2H3,(H,41,42,43)(H,44,45,46)(H,47,48,49)/b39-37+,40-38+
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n/an/a 2.65E+4n/an/an/an/a7.4n/a



Beckman Research Institute of the City of Hope



Assay Description
Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...


ACS Chem Biol 8: 1435-41 (2013)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2KH0KZN
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM103828
PNG
(SPI-03)
Show SMILES Cc1cc(ccc1-c1ccc(cc1C)\N=N\c1cc(c2ccccc2c1N)S(O)(=O)=O)\N=N\c1cc(c2ccccc2c1N)S(O)(=O)=O
Show InChI InChI=1S/C34H28N6O6S2/c1-19-15-21(37-39-29-17-31(47(41,42)43)25-7-3-5-9-27(25)33(29)35)11-13-23(19)24-14-12-22(16-20(24)2)38-40-30-18-32(48(44,45)46)26-8-4-6-10-28(26)34(30)36/h3-18H,35-36H2,1-2H3,(H,41,42,43)(H,44,45,46)/b39-37+,40-38+
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n/an/a 2.03E+4n/an/an/an/a7.4n/a



Beckman Research Institute of the City of Hope



Assay Description
Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...


ACS Chem Biol 8: 1435-41 (2013)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2KH0KZN
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM103829
PNG
(SPI-04)
Show SMILES Nc1ccc(\N=N\c2ccc(\C=C\c3ccc(cc3S(O)(=O)=O)\N=N\c3ccc(N)c4ccc(cc34)S([O-])(=O)=O)c(c2)S(O)(=O)=O)c2cc(ccc12)S(O)(=O)=O
Show InChI InChI=1S/C34H26N6O12S4/c35-29-11-13-31(27-17-23(53(41,42)43)7-9-25(27)29)39-37-21-5-3-19(33(15-21)55(47,48)49)1-2-20-4-6-22(16-34(20)56(50,51)52)38-40-32-14-12-30(36)26-10-8-24(18-28(26)32)54(44,45)46/h1-18H,35-36H2,(H,41,42,43)(H,44,45,46)(H,47,48,49)(H,50,51,52)/p-1/b2-1+,39-37+,40-38+
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n/an/a 1.12E+4n/an/an/an/a7.4n/a



Beckman Research Institute of the City of Hope



Assay Description
Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...


ACS Chem Biol 8: 1435-41 (2013)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2KH0KZN
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM103830
PNG
(SPI-05)
Show SMILES Nc1ccc(\N=N\c2ccc(\C=C\c3ccc(cc3S(O)(=O)=O)\N=N\c3ccc(N)c4ccccc34)c(c2)S(O)(=O)=O)c2ccccc12
Show InChI InChI=1S/C34H26N6O6S2/c35-29-15-17-31(27-7-3-1-5-25(27)29)39-37-23-13-11-21(33(19-23)47(41,42)43)9-10-22-12-14-24(20-34(22)48(44,45)46)38-40-32-18-16-30(36)26-6-2-4-8-28(26)32/h1-20H,35-36H2,(H,41,42,43)(H,44,45,46)/b10-9+,39-37+,40-38+
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n/an/a>6.00E+4n/an/an/an/a7.4n/a



Beckman Research Institute of the City of Hope



Assay Description
Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...


ACS Chem Biol 8: 1435-41 (2013)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2KH0KZN
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM103835
PNG
(SPI-10)
Show SMILES Nc1ccc(\N=N\c2cccc(c2)S([O-])(=O)=O)c2ccccc12
Show InChI InChI=1S/C16H13N3O3S/c17-15-8-9-16(14-7-2-1-6-13(14)15)19-18-11-4-3-5-12(10-11)23(20,21)22/h1-10H,17H2,(H,20,21,22)/p-1/b19-18+
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n/an/a 1.11E+4n/an/an/an/a7.4n/a



Beckman Research Institute of the City of Hope



Assay Description
Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...


ACS Chem Biol 8: 1435-41 (2013)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2KH0KZN
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM103832
PNG
(SPI-07)
Show SMILES Cc1cc(N)ccc1\N=N\c1cc(c2cccc(c2c1)S([O-])(=O)=O)S([O-])(=O)=O
Show InChI InChI=1S/C17H15N3O6S2/c1-10-7-11(18)5-6-15(10)20-19-12-8-14-13(17(9-12)28(24,25)26)3-2-4-16(14)27(21,22)23/h2-9H,18H2,1H3,(H,21,22,23)(H,24,25,26)/p-2/b20-19+
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n/an/a>6.00E+7n/an/an/an/a7.4n/a



Beckman Research Institute of the City of Hope



Assay Description
Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...


ACS Chem Biol 8: 1435-41 (2013)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2KH0KZN
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM103833
PNG
(SPI-08)
Show SMILES Nc1c(cc(c2ccccc12)S([O-])(=O)=O)\N=N\c1ccccc1
Show InChI InChI=1S/C16H13N3O3S/c17-16-13-9-5-4-8-12(13)15(23(20,21)22)10-14(16)19-18-11-6-2-1-3-7-11/h1-10H,17H2,(H,20,21,22)/p-1/b19-18+
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n/an/a>6.00E+7n/an/an/an/a7.4n/a



Beckman Research Institute of the City of Hope



Assay Description
Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...


ACS Chem Biol 8: 1435-41 (2013)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2KH0KZN
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM103834
PNG
(SPI-09)
Show SMILES Nc1ccc2cc(cc(c2c1\N=N\c1ccc(cc1)S(O)(=O)=O)S(O)(=O)=O)S(O)(=O)=O
Show InChI InChI=1S/C16H13N3O9S3/c17-13-6-1-9-7-12(30(23,24)25)8-14(31(26,27)28)15(9)16(13)19-18-10-2-4-11(5-3-10)29(20,21)22/h1-8H,17H2,(H,20,21,22)(H,23,24,25)(H,26,27,28)/b19-18+
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n/an/a>6.00E+7n/an/an/an/a7.4n/a



Beckman Research Institute of the City of Hope



Assay Description
Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...


ACS Chem Biol 8: 1435-41 (2013)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2KH0KZN
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM103835
PNG
(SPI-10)
Show SMILES Nc1ccc(\N=N\c2cccc(c2)S([O-])(=O)=O)c2ccccc12
Show InChI InChI=1S/C16H13N3O3S/c17-15-8-9-16(14-7-2-1-6-13(14)15)19-18-11-4-3-5-12(10-11)23(20,21)22/h1-10H,17H2,(H,20,21,22)/p-1/b19-18+
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n/an/a>6.00E+7n/an/an/an/a7.4n/a



Beckman Research Institute of the City of Hope



Assay Description
Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...


ACS Chem Biol 8: 1435-41 (2013)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2KH0KZN
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM103826
PNG
(SPI-01)
Show SMILES Nc1ccc2ccccc2c1\N=N\c1ccc(\C=C\c2ccc(cc2S(O)(=O)=O)\N=N\c2c(N)ccc3ccccc23)c(c1)S(O)(=O)=O
Show InChI InChI=1S/C34H26N6O6S2/c35-29-17-13-21-5-1-3-7-27(21)33(29)39-37-25-15-11-23(31(19-25)47(41,42)43)9-10-24-12-16-26(20-32(24)48(44,45)46)38-40-34-28-8-4-2-6-22(28)14-18-30(34)36/h1-20H,35-36H2,(H,41,42,43)(H,44,45,46)/b10-9+,39-37+,40-38+
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n/an/a 1.88E+3n/an/an/an/a7.4n/a



Beckman Research Institute of the City of Hope



Assay Description
Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...


ACS Chem Biol 8: 1435-41 (2013)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2KH0KZN
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM103827
PNG
(SPI-02)
Show SMILES Cc1cc(ccc1\N=N\c1c(N)ccc2cc(ccc12)S(O)(=O)=O)-c1ccc(\N=N\c2c(N)c(cc3cc(ccc23)S(O)(=O)=O)S(O)(=O)=O)c(C)c1
Show InChI InChI=1S/C34H28N6O9S3/c1-18-13-20(4-11-29(18)37-39-33-26-8-6-24(50(41,42)43)15-22(26)3-10-28(33)35)21-5-12-30(19(2)14-21)38-40-34-27-9-7-25(51(44,45)46)16-23(27)17-31(32(34)36)52(47,48)49/h3-17H,35-36H2,1-2H3,(H,41,42,43)(H,44,45,46)(H,47,48,49)/b39-37+,40-38+
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n/an/a 2.08E+3n/an/an/an/a7.4n/a



Beckman Research Institute of the City of Hope



Assay Description
Assays were performedby incubating SENPs with various concentrations of the inhibitor (0−60 μM) at RT for 10 min in assay buffer (50 mM Tr...


ACS Chem Biol 8: 1435-41 (2013)


Article DOI: 10.1021/cb400177q
BindingDB Entry DOI: 10.7270/Q2KH0KZN
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM81512
PNG
(VEA-417)
Show SMILES NC(=O)CNC(=O)c1ccc(cc1)C(=O)NNC(=O)[C@H]1O[C@@H]1C(=O)N(Cc1cccc2ccccc12)Cc1cccc2ccccc12
Show InChI InChI=1S/C36H31N5O6/c37-30(42)19-38-33(43)24-15-17-25(18-16-24)34(44)39-40-35(45)31-32(47-31)36(46)41(20-26-11-5-9-22-7-1-3-13-28(22)26)21-27-12-6-10-23-8-2-4-14-29(23)27/h1-18,31-32H,19-21H2,(H2,37,42)(H,38,43)(H,39,44)(H,40,45)/t31-,32-/m0/s1
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n/an/a 3.25E+4n/an/an/an/a8.037



Stanford University



Assay Description
The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ...


Chem Biol 18: 722-32 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.008
BindingDB Entry DOI: 10.7270/Q2542M2N
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM81511
PNG
(VEA-260)
Show SMILES OC(=O)c1cccc(c1)C(=O)NCc1ccc(cc1)C(=O)NNC(=O)[C@H]1O[C@@H]1C(=O)N(Cc1cccc2ccccc12)Cc1cccc2ccccc12
Show InChI InChI=1S/C42H34N4O7/c47-38(30-12-7-13-31(22-30)42(51)52)43-23-26-18-20-29(21-19-26)39(48)44-45-40(49)36-37(53-36)41(50)46(24-32-14-5-10-27-8-1-3-16-34(27)32)25-33-15-6-11-28-9-2-4-17-35(28)33/h1-22,36-37H,23-25H2,(H,43,47)(H,44,48)(H,45,49)(H,51,52)/t36-,37-/m0/s1
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n/an/a 7.10E+3n/an/an/an/a8.037



Stanford University



Assay Description
The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ...


Chem Biol 18: 722-32 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.008
BindingDB Entry DOI: 10.7270/Q2542M2N
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM81510
PNG
(JCP-666)
Show SMILES OC(=O)CN(NC(=O)c1ccc(CNC(=O)c2cccc(c2)C(O)=O)cc1)C(=O)[C@H]1O[C@@H]1C(=O)N(Cc1cccc2ccccc12)Cc1cccc2ccccc12
Show InChI InChI=1S/C44H36N4O9/c49-37(50)26-48(46-41(52)30-20-18-27(19-21-30)23-45-40(51)31-12-7-13-32(22-31)44(55)56)43(54)39-38(57-39)42(53)47(24-33-14-5-10-28-8-1-3-16-35(28)33)25-34-15-6-11-29-9-2-4-17-36(29)34/h1-22,38-39H,23-26H2,(H,45,51)(H,46,52)(H,49,50)(H,55,56)/t38-,39-/m0/s1
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n/an/a 1.38E+4n/an/an/an/a8.037



Stanford University



Assay Description
The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ...


Chem Biol 18: 722-32 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.008
BindingDB Entry DOI: 10.7270/Q2542M2N
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM81517
PNG
(VEA-561)
Show SMILES CC(C)C[C@H](NC(=O)Cc1ccc(O)c(c1)N(=O)=O)C(=O)N[C@@H](CCCN=C(N)N)C(=O)NCC(=O)NCC(=O)COC(=O)c1c2ccccc2cc2ccccc12
Show InChI InChI=1S/C40H46N8O10/c1-23(2)16-31(46-34(51)18-24-13-14-33(50)32(17-24)48(56)57)38(54)47-30(12-7-15-43-40(41)42)37(53)45-21-35(52)44-20-27(49)22-58-39(55)36-28-10-5-3-8-25(28)19-26-9-4-6-11-29(26)36/h3-6,8-11,13-14,17,19,23,30-31,50H,7,12,15-16,18,20-22H2,1-2H3,(H,44,52)(H,45,53)(H,46,51)(H,47,54)(H4,41,42,43)/t30-,31-/m0/s1
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n/an/a>2.50E+4n/an/an/an/a8.037



Stanford University



Assay Description
The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ...


Chem Biol 18: 722-32 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.008
BindingDB Entry DOI: 10.7270/Q2542M2N
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM81516
PNG
(VEA-500)
Show SMILES C[C@H](O)C(NC(=O)[C@H](CCC(N)=O)NC(=O)[C@H](CCC(N)=O)NC(=O)Cc1ccc(O)c(c1)N(=O)=O)C(=O)NCC(=O)NCC(=O)COC(=O)c1c2ccccc2cc2ccccc12
Show InChI InChI=1S/C42H46N8O14/c1-22(51)38(41(60)46-20-36(57)45-19-26(52)21-64-42(61)37-27-8-4-2-6-24(27)18-25-7-3-5-9-28(25)37)49-40(59)30(12-15-34(44)55)48-39(58)29(11-14-33(43)54)47-35(56)17-23-10-13-32(53)31(16-23)50(62)63/h2-10,13,16,18,22,29-30,38,51,53H,11-12,14-15,17,19-21H2,1H3,(H2,43,54)(H2,44,55)(H,45,57)(H,46,60)(H,47,56)(H,48,58)(H,49,59)/t22-,29-,30-,38?/m0/s1
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n/an/a>2.00E+4n/an/an/an/a8.037



Stanford University



Assay Description
The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ...


Chem Biol 18: 722-32 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.008
BindingDB Entry DOI: 10.7270/Q2542M2N
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM81515
PNG
(VEA-499)
Show SMILES C[C@H](O)C(NC(=O)[C@H](CCC(N)=O)NC(=O)Cc1ccc(O)c(c1)N(=O)=O)C(=O)NCC(=O)NCC(=O)COC(=O)c1c2ccccc2cc2ccccc12
Show InChI InChI=1S/C37H38N6O12/c1-20(44)34(42-35(50)27(11-13-30(38)47)41-31(48)15-21-10-12-29(46)28(14-21)43(53)54)36(51)40-18-32(49)39-17-24(45)19-55-37(52)33-25-8-4-2-6-22(25)16-23-7-3-5-9-26(23)33/h2-10,12,14,16,20,27,34,44,46H,11,13,15,17-19H2,1H3,(H2,38,47)(H,39,49)(H,40,51)(H,41,48)(H,42,50)/t20-,27-,34?/m0/s1
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n/an/a 3.60E+3n/an/an/an/a8.037



Stanford University



Assay Description
The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ...


Chem Biol 18: 722-32 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.008
BindingDB Entry DOI: 10.7270/Q2542M2N
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM81514
PNG
(VEA-401)
Show SMILES OC(=O)c1cccc(c1)C(=O)NCc1ccc(cc1)C(=O)NCC(=O)COC(=O)c1c2ccccc2cc2ccccc12
Show InChI InChI=1S/C34H26N2O7/c37-27(20-43-34(42)30-28-10-3-1-6-23(28)16-24-7-2-4-11-29(24)30)19-36-31(38)22-14-12-21(13-15-22)18-35-32(39)25-8-5-9-26(17-25)33(40)41/h1-17H,18-20H2,(H,35,39)(H,36,38)(H,40,41)
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n/an/a 2.31E+4n/an/an/an/a8.037



Stanford University



Assay Description
The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ...


Chem Biol 18: 722-32 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.008
BindingDB Entry DOI: 10.7270/Q2542M2N
More data for this
Ligand-Target Pair
Sentrin-specific protease 1 (SENP1)


(Homo sapiens (Human))
BDBM81513
PNG
(VEA-422)
Show SMILES NC(=O)[C@H](CC(O)=O)NC(=O)c1ccc(cc1)C(=O)NNC(=O)[C@H]1O[C@@H]1C(=O)N(Cc1cccc2ccccc12)Cc1cccc2ccccc12
Show InChI InChI=1S/C38H33N5O8/c39-34(46)30(19-31(44)45)40-35(47)24-15-17-25(18-16-24)36(48)41-42-37(49)32-33(51-32)38(50)43(20-26-11-5-9-22-7-1-3-13-28(22)26)21-27-12-6-10-23-8-2-4-14-29(23)27/h1-18,30,32-33H,19-21H2,(H2,39,46)(H,40,47)(H,41,48)(H,42,49)(H,44,45)/t30-,32-,33-/m0/s1
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n/an/a 2.24E+4n/an/an/an/a8.037



Stanford University



Assay Description
The fluorogenic substrate library screen was performed with hSENP1 in low salt tris buffer at final concentration of 2uM. Fluorophore release (AFC) ...


Chem Biol 18: 722-32 (2011)


Article DOI: 10.1016/j.chembiol.2011.05.008
BindingDB Entry DOI: 10.7270/Q2542M2N
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM52075
PNG
(1,3-dimethyl-5-(3-methylphenyl)pyrimido[1,2]pyrrol...)
Show SMILES Cc1cccc(c1)-c1c2c(n(C)c(=O)n(C)c2=O)c2cccnn12
Show InChI InChI=1S/C18H16N4O2/c1-11-6-4-7-12(10-11)15-14-16(13-8-5-9-19-22(13)15)20(2)18(24)21(3)17(14)23/h4-10H,1-3H3
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n/an/a 1.13E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM94771
PNG
(4-(5-Amino-1,3-dioxo-1,3-dihydro-isoindol-2-yl)-bu...)
Show SMILES Nc1ccc2C(=O)N(CCCC(O)=O)C(=O)c2c1
Show InChI InChI=1S/C12H12N2O4/c13-7-3-4-8-9(6-7)12(18)14(11(8)17)5-1-2-10(15)16/h3-4,6H,1-2,5,13H2,(H,15,16)
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n/an/a 1.90E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM94772
PNG
((3-Amino-7-methyl-thieno[2,3-b]quinolin-2-yl)-morp...)
Show SMILES Cc1ccc2cc3c(N)c(sc3nc2c1)C(=O)N1CCOCC1
Show InChI InChI=1S/C17H17N3O2S/c1-10-2-3-11-9-12-14(18)15(23-16(12)19-13(11)8-10)17(21)20-4-6-22-7-5-20/h2-3,8-9H,4-7,18H2,1H3
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n/an/a 3.06E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM87811
PNG
(2-(1-naphthalenyl)-N-[2,2,2-trichloro-1-[[(2-chlor...)
Show SMILES Clc1ccccc1NC(=S)NC(NC(=O)Cc1cccc2ccccc12)C(Cl)(Cl)Cl
Show InChI InChI=1S/C21H17Cl4N3OS/c22-16-10-3-4-11-17(16)26-20(30)28-19(21(23,24)25)27-18(29)12-14-8-5-7-13-6-1-2-9-15(13)14/h1-11,19H,12H2,(H,27,29)(H2,26,28,30)
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n/an/a 8.71E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM52089
PNG
(2-(4-methoxyphenyl)-1,3-dihydro-1,3,2-benzodiazaph...)
Show SMILES COc1ccc(cc1)P1(=O)Nc2ccccc2N1
Show InChI InChI=1S/C13H13N2O2P/c1-17-10-6-8-11(9-7-10)18(16)14-12-4-2-3-5-13(12)15-18/h2-9H,1H3,(H2,14,15,16)
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n/an/a>8.00E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM39962
PNG
(7-[[1-(3-methylphenyl)benzimidazol-2-yl]sulfanylme...)
Show SMILES Cc1cccc(c1)-n1c(SCc2cc(=O)n3ccsc3n2)nc2ccccc12
Show InChI InChI=1S/C21H16N4OS2/c1-14-5-4-6-16(11-14)25-18-8-3-2-7-17(18)23-21(25)28-13-15-12-19(26)24-9-10-27-20(24)22-15/h2-12H,13H2,1H3
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n/an/a 9.71E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM88820
PNG
(2-(7-methoxy-4-methyl-quinolin-2-yl)sulfanyl-1-mor...)
Show SMILES COc1ccc2c(C)cc(SCC(=O)N3CCOCC3)nc2c1
Show InChI InChI=1S/C17H20N2O3S/c1-12-9-16(18-15-10-13(21-2)3-4-14(12)15)23-11-17(20)19-5-7-22-8-6-19/h3-4,9-10H,5-8,11H2,1-2H3
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n/an/a 7.01E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM94773
PNG
(3-(2,5-dioxo-1-pyrrolidinyl)-N-(1-ethyl-2-oxo-6-be...)
Show SMILES CCN1C(=O)c2cccc3c(NC(=O)c4cccc(c4)-n4c(O)ccc4O)ccc1c23
Show InChI InChI=1S/C24H19N3O4/c1-2-26-19-10-9-18(16-7-4-8-17(22(16)19)24(26)31)25-23(30)14-5-3-6-15(13-14)27-20(28)11-12-21(27)29/h3-13,28-29H,2H2,1H3,(H,25,30)
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n/an/a 1.13E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM94774
PNG
(5-methyl-3H-[1,2,5]oxadiazolo[3,4-h][1,6]naphthyri...)
Show SMILES Cc1nc2nonc2c2nccc(O)c12
Show InChI InChI=1S/C9H6N4O2/c1-4-6-5(14)2-3-10-7(6)8-9(11-4)13-15-12-8/h2-3H,1H3,(H,10,14)
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n/an/a 8.04E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM94775
PNG
(5-amino-2-(2-oxolanylmethyl)isoindole-1,3-dione | ...)
Show SMILES Nc1ccc2C(=O)N(CC3CCCO3)C(=O)c2c1
Show InChI InChI=1S/C13H14N2O3/c14-8-3-4-10-11(6-8)13(17)15(12(10)16)7-9-2-1-5-18-9/h3-4,6,9H,1-2,5,7,14H2
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n/an/a 8.20E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM94776
PNG
((2Z)-5-(2,4-dimethoxyphenyl)-6-ethanoyl-2-(furan-2...)
Show SMILES COc1ccc(C2C(C(C)=O)=C(C)N=c3sc(=Cc4ccco4)c(=O)n23)c(OC)c1
Show InChI InChI=1S/C22H20N2O5S/c1-12-19(13(2)25)20(16-8-7-14(27-3)10-17(16)28-4)24-21(26)18(30-22(24)23-12)11-15-6-5-9-29-15/h5-11,20H,1-4H3
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n/an/a 2.02E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM50847
PNG
(6-(3-hydroxypropyl)-2,3-dihydro-[1,4]dithiino[2,3-...)
Show SMILES OCCCN1C(=O)C2=C(SCCS2)C1=O
Show InChI InChI=1S/C9H11NO3S2/c11-3-1-2-10-8(12)6-7(9(10)13)15-5-4-14-6/h11H,1-5H2
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n/an/a 3.52E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM34196
PNG
(7-(4,5,6,7-tetrahydro-2,1,3-benzoxadiazol-4-yl)-2,...)
Show SMILES Nc1ccc(C2CCCc3nonc23)c2nonc12
Show InChI InChI=1S/C12H11N5O2/c13-8-5-4-7(11-12(8)17-19-16-11)6-2-1-3-9-10(6)15-18-14-9/h4-6H,1-3,13H2
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n/an/a 3.94E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM94777
PNG
(7,9-bis(trifluoromethyl)pyrido[2,3]thieno[2,4-b]py...)
Show SMILES Nc1nc(N)c2sc3nc(cc(c3c2n1)C(F)(F)F)C(F)(F)F
Show InChI InChI=1S/C11H5F6N5S/c12-10(13,14)2-1-3(11(15,16)17)20-8-4(2)5-6(23-8)7(18)22-9(19)21-5/h1H,(H4,18,19,21,22)
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n/an/a 1.67E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM83491
PNG
((6E)-4-chloranyl-6-[4-(furan-2-yl)-1,3-dihydro-1,5...)
Show SMILES Oc1ccc(Cl)cc1C1=Nc2ccccc2N=C(C1)c1ccco1
Show InChI InChI=1S/C19H13ClN2O2/c20-12-7-8-18(23)13(10-12)16-11-17(19-6-3-9-24-19)22-15-5-2-1-4-14(15)21-16/h1-10,23H,11H2
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n/an/a 8.31E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM83493
PNG
(3-Amino-6-methyl-thieno[2,3-b]quinoline-2-carboxyl...)
Show SMILES Cc1ccc2nc3sc(C(=O)NCc4ccco4)c(N)c3cc2c1
Show InChI InChI=1S/C18H15N3O2S/c1-10-4-5-14-11(7-10)8-13-15(19)16(24-18(13)21-14)17(22)20-9-12-3-2-6-23-12/h2-8H,9,19H2,1H3,(H,20,22)
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n/an/a 7.17E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM94778
PNG
(2-Amino-7-phenylamino-4-pyridin-4-yl-4H-chromene-3...)
Show SMILES N=C1Oc2cc(Nc3ccccc3)ccc2C(C1C#N)c1ccncc1
Show InChI InChI=1S/C21H16N4O/c22-13-18-20(14-8-10-24-11-9-14)17-7-6-16(12-19(17)26-21(18)23)25-15-4-2-1-3-5-15/h1-12,18,20,23,25H
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n/an/a 3.05E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM71909
PNG
(1-(4-methylphenyl)-4-oxidanylidene-7-phenyl-3-(phe...)
Show SMILES Cc1ccc(cc1)-n1c2ccc(n[n+]2c([O-])c(Cc2ccccc2)c1=O)-c1ccccc1
Show InChI InChI=1S/C27H21N3O2/c1-19-12-14-22(15-13-19)29-25-17-16-24(21-10-6-3-7-11-21)28-30(25)27(32)23(26(29)31)18-20-8-4-2-5-9-20/h2-17H,18H2,1H3
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n/an/a 6.35E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM52244
PNG
(1-(4-chlorophenyl)-4-oxidanylidene-7-phenyl-3-(phe...)
Show SMILES [O-]c1c(Cc2ccccc2)c(=O)n(-c2ccc(Cl)cc2)c2ccc(n[n+]12)-c1ccccc1
Show InChI InChI=1S/C26H18ClN3O2/c27-20-11-13-21(14-12-20)29-24-16-15-23(19-9-5-2-6-10-19)28-30(24)26(32)22(25(29)31)17-18-7-3-1-4-8-18/h1-16H,17H2
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n/an/a 5.94E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM94779
PNG
(2-(2-allyloxyethyl)-4,7-diphenyl-3a,4,7,7a-tetrahy...)
Show SMILES C=CCOCCN1C(=O)C2C(C(C=CC2c2ccccc2)c2ccccc2)C1=O
Show InChI InChI=1S/C25H25NO3/c1-2-16-29-17-15-26-24(27)22-20(18-9-5-3-6-10-18)13-14-21(23(22)25(26)28)19-11-7-4-8-12-19/h2-14,20-23H,1,15-17H2
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n/an/a 4.30E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM58966
PNG
(MLS000520196 | N-cyclohexyl-2-(5-methyl-2-furanyl)...)
Show SMILES Cc1ccc(o1)-c1nc2ncccn2c1NC1CCCCC1
Show InChI InChI=1S/C17H20N4O/c1-12-8-9-14(22-12)15-16(19-13-6-3-2-4-7-13)21-11-5-10-18-17(21)20-15/h5,8-11,13,19H,2-4,6-7H2,1H3
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n/an/a 8.98E+3n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
sentrin-specific protease 1


(Homo sapiens (Human))
BDBM52296
PNG
(3-[2-(9-Methoxy-indolo[2,3-b]quinoxalin-6-yl)-ethy...)
Show SMILES COc1ccc2n(CCn3c4ccccc4oc3=O)c3nc4ccccc4nc3c2c1
Show InChI InChI=1S/C24H18N4O3/c1-30-15-10-11-19-16(14-15)22-23(26-18-7-3-2-6-17(18)25-22)27(19)12-13-28-20-8-4-5-9-21(20)31-24(28)29/h2-11,14H,12-13H2,1H3
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n/an/a 2.09E+4n/an/an/an/an/an/a



Burnham Center for Chemical Genomics

Curated by PubChem BioAssay




PubChem Bioassay (2012)


BindingDB Entry DOI: 10.7270/Q2R49PCF
More data for this
Ligand-Target Pair
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