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Found 6400 hits Enz. Inhib. hit(s) with Target = 'Tyrosine-protein kinase JAK1'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198642
PNG
(US9216999, 435a | US9556187, Example 435a)
Show SMILES N#CC[C@H]1CC[C@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C15H16N6/c16-7-5-10-1-3-11(4-2-10)13-14-12-6-8-17-15(12)18-9-21(14)20-19-13/h6,8-11,17H,1-5H2/t10-,11+
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n/an/a 5.40n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198643
PNG
(US9216999, 435b | US9556187, Example 435b)
Show SMILES N#CC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C15H16N6/c16-7-5-10-1-3-11(4-2-10)13-14-12-6-8-17-15(12)18-9-21(14)20-19-13/h6,8-11,17H,1-5H2/t10-,11-
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n/an/a 0.110n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198644
PNG
(US9216999, 436 | US9556187, Example 436)
Show InChI InChI=1S/C17H19N5O2/c1-2-24-14(23)9-11-3-5-12(6-4-11)15-16-13-7-8-18-17(13)19-10-22(16)21-20-15/h7-10,12,18H,2-6H2,1H3/b11-9-
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n/an/a 35n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198645
PNG
(US9216999, 437 | US9556187, Example 437)
Show InChI InChI=1S/C16H16N6/c1-10(8-17)11-2-4-12(5-3-11)14-15-13-6-7-18-16(13)19-9-22(15)21-20-14/h6-7,9,12,18H,2-5H2,1H3/b11-10-
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n/an/a 20n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198646
PNG
(US9216999, 438 | US9556187, Example 438)
Show SMILES CCOC(=O)CC1CCC(CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C17H21N5O2/c1-2-24-14(23)9-11-3-5-12(6-4-11)15-16-13-7-8-18-17(13)19-10-22(16)21-20-15/h7-8,10-12,18H,2-6,9H2,1H3
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n/an/a 17n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198647
PNG
(US9216999, 439a | US9556187, Example 439a)
Show SMILES CC(C#N)[C@H]1CC[C@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C16H18N6/c1-10(8-17)11-2-4-12(5-3-11)14-15-13-6-7-18-16(13)19-9-22(15)21-20-14/h6-7,9-12,18H,2-5H2,1H3/t10?,11-,12+
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n/an/a 130n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198648
PNG
(US9216999, 439b | US9556187, Example 439b)
Show SMILES CC(C#N)[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C16H18N6/c1-10(8-17)11-2-4-12(5-3-11)14-15-13-6-7-18-16(13)19-9-22(15)21-20-14/h6-7,9-12,18H,2-5H2,1H3/t10?,11-,12-
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n/an/a 3.10n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198649
PNG
(US9216999, 440 | US9556187, Example 440)
Show SMILES N#C\C=C\[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C16H16N6/c17-8-1-2-11-3-5-12(6-4-11)14-15-13-7-9-18-16(13)19-10-22(15)21-20-14/h1-2,7,9-12,18H,3-6H2/b2-1+/t11-,12-
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n/an/a 5.30n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198650
PNG
(US9216999, 441 | US9556187, Example 441)
Show SMILES N#CCC[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C16H18N6/c17-8-1-2-11-3-5-12(6-4-11)14-15-13-7-9-18-16(13)19-10-22(15)21-20-14/h7,9-12,18H,1-6H2/t11-,12-
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n/an/a 1.60n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198651
PNG
(US9216999, 442a | US9556187, Example 442a)
Show SMILES FC(F)(F)CNC(=O)C[C@H]1CC[C@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C17H19F3N6O/c18-17(19,20)8-22-13(27)7-10-1-3-11(4-2-10)14-15-12-5-6-21-16(12)23-9-26(15)25-24-14/h5-6,9-11,21H,1-4,7-8H2,(H,22,27)/t10-,11+
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n/an/a 27n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198652
PNG
(US9216999, 442b | US9556187, Example 442b)
Show SMILES FC(F)(F)CNC(=O)C[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C17H19F3N6O/c18-17(19,20)8-22-13(27)7-10-1-3-11(4-2-10)14-15-12-5-6-21-16(12)23-9-26(15)25-24-14/h5-6,9-11,21H,1-4,7-8H2,(H,22,27)/t10-,11-
PDB

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n/an/a 3.20n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198653
PNG
(US9216999, 443a | US9556187, Example 443a)
Show SMILES O=C(C[C@H]1CC[C@H](CC1)c1nnn2cnc3[nH]ccc3c12)NCC#N
Show InChI InChI=1S/C17H19N7O/c18-6-8-19-14(25)9-11-1-3-12(4-2-11)15-16-13-5-7-20-17(13)21-10-24(16)23-22-15/h5,7,10-12,20H,1-4,8-9H2,(H,19,25)/t11-,12+
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n/an/a 26n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198654
PNG
(US9216999, 443b | US9556187, Example 443b)
Show SMILES O=C(C[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12)NCC#N
Show InChI InChI=1S/C17H19N7O/c18-6-8-19-14(25)9-11-1-3-12(4-2-11)15-16-13-5-7-20-17(13)21-10-24(16)23-22-15/h5,7,10-12,20H,1-4,8-9H2,(H,19,25)/t11-,12-
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n/an/a 10n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198655
PNG
(US9216999, 444 | US9556187, Example 444)
Show SMILES N#CC1CC11CCC(CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C16H16N6/c17-8-11-7-16(11)4-1-10(2-5-16)13-14-12-3-6-18-15(12)19-9-22(14)21-20-13/h3,6,9-11,18H,1-2,4-5,7H2
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n/an/a 3.40n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198656
PNG
(US9216999, 445 | US9556187, Example 445)
Show SMILES OC12CC3CC(C1)CC(C3)(C2)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C17H19N5O/c23-17-6-10-3-11(7-17)5-16(4-10,8-17)14-13-12-1-2-18-15(12)19-9-22(13)21-20-14/h1-2,9-11,18,23H,3-8H2
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n/an/a 31n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198578
PNG
(US9216999, 375 | US9556187, Example 375)
Show SMILES N#Cc1ccc(CCN2CCC(CC2)c2nnn3cnc4[nH]ccc4c23)cc1
Show InChI InChI=1S/C21H21N7/c22-13-16-3-1-15(2-4-16)6-10-27-11-7-17(8-12-27)19-20-18-5-9-23-21(18)24-14-28(20)26-25-19/h1-5,9,14,17,23H,6-8,10-12H2
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n/an/a 47n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198579
PNG
(US9216999, 376 | US9556187, Example 376)
Show SMILES N#Cc1ccc(cc1)N1CCC(CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C19H17N7/c20-11-13-1-3-15(4-2-13)25-9-6-14(7-10-25)17-18-16-5-8-21-19(16)22-12-26(18)24-23-17/h1-5,8,12,14,21H,6-7,9-10H2
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n/an/a 19n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198580
PNG
(US9216999, 377 | US9556187, Example 377)
Show SMILES Clc1c[nH]c2ncn3nnc(C4CCN(Cc5ccc(cc5)C#N)CC4)c3c12
Show InChI InChI=1S/C20H18ClN7/c21-16-10-23-20-17(16)19-18(25-26-28(19)12-24-20)15-5-7-27(8-6-15)11-14-3-1-13(9-22)2-4-14/h1-4,10,12,15,23H,5-8,11H2
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n/an/a 4.5n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198581
PNG
(US9216999, 378 | US9556187, Example 378)
Show SMILES O[C@H]1Cc2ccccc2[C@H]1NC1CCC(CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C22H24N6O/c29-18-11-14-3-1-2-4-16(14)20(18)25-15-7-5-13(6-8-15)19-21-17-9-10-23-22(17)24-12-28(21)27-26-19/h1-4,9-10,12-13,15,18,20,23,25,29H,5-8,11H2/t13?,15?,18-,20+/m0/s1
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n/an/a 4n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198582
PNG
(US9216999, 379 | US9556187, Example 379)
Show SMILES O[C@@H]1Cc2ccccc2[C@@H]1NC1CCC(CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C22H24N6O/c29-18-11-14-3-1-2-4-16(14)20(18)25-15-7-5-13(6-8-15)19-21-17-9-10-23-22(17)24-12-28(21)27-26-19/h1-4,9-10,12-13,15,18,20,23,25,29H,5-8,11H2/t13?,15?,18-,20+/m1/s1
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n/an/a 13n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198583
PNG
(US9216999, 380 | US9556187, Example 380)
Show SMILES N#CCCN(CCC#N)C1CCC(CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C19H22N8/c20-8-1-11-26(12-2-9-21)15-5-3-14(4-6-15)17-18-16-7-10-22-19(16)23-13-27(18)25-24-17/h7,10,13-15,22H,1-6,11-12H2
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198584
PNG
(US9216999, 381a | US9556187, Example 381a)
Show SMILES Fc1ccc(N[C@H]2CC[C@H](CC2)c2nnn3cnc4[nH]ccc4c23)cc1
Show InChI InChI=1S/C19H19FN6/c20-13-3-7-15(8-4-13)23-14-5-1-12(2-6-14)17-18-16-9-10-21-19(16)22-11-26(18)25-24-17/h3-4,7-12,14,21,23H,1-2,5-6H2/t12-,14+
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198585
PNG
(US9216999, 381b | US9556187, Example 381b)
Show SMILES Fc1ccc(N[C@H]2CC[C@@H](CC2)c2nnn3cnc4[nH]ccc4c23)cc1
Show InChI InChI=1S/C19H19FN6/c20-13-3-7-15(8-4-13)23-14-5-1-12(2-6-14)17-18-16-9-10-21-19(16)22-11-26(18)25-24-17/h3-4,7-12,14,21,23H,1-2,5-6H2/t12-,14-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198586
PNG
(US9216999, 382a | US9556187, Example 382a)
Show SMILES FC(F)(Br)CN[C@H]1CC[C@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C15H17BrF2N6/c16-15(17,18)7-20-10-3-1-9(2-4-10)12-13-11-5-6-19-14(11)21-8-24(13)23-22-12/h5-6,8-10,19-20H,1-4,7H2/t9-,10+
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198587
PNG
(US9216999, 382b | US9556187, Example 382b)
Show SMILES FC(F)(Br)CN[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C15H17BrF2N6/c16-15(17,18)7-20-10-3-1-9(2-4-10)12-13-11-5-6-19-14(11)21-8-24(13)23-22-12/h5-6,8-10,19-20H,1-4,7H2/t9-,10-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198588
PNG
(US9216999, 383a | US9556187, Example 383a)
Show SMILES FC(F)(F)C(F)(F)CN[C@H]1CC[C@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C16H17F5N6/c17-15(18,16(19,20)21)7-23-10-3-1-9(2-4-10)12-13-11-5-6-22-14(11)24-8-27(13)26-25-12/h5-6,8-10,22-23H,1-4,7H2/t9-,10+
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198589
PNG
(US9216999, 383b | US9556187, Example 383b)
Show SMILES FC(F)(F)C(F)(F)CN[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C16H17F5N6/c17-15(18,16(19,20)21)7-23-10-3-1-9(2-4-10)12-13-11-5-6-22-14(11)24-8-27(13)26-25-12/h5-6,8-10,22-23H,1-4,7H2/t9-,10-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198590
PNG
(US9216999, 384a | US9556187, Example 384a)
Show SMILES FC(F)(F)CNC(=O)CN[C@H]1CC[C@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C17H20F3N7O/c18-17(19,20)8-23-13(28)7-22-11-3-1-10(2-4-11)14-15-12-5-6-21-16(12)24-9-27(15)26-25-14/h5-6,9-11,21-22H,1-4,7-8H2,(H,23,28)/t10-,11+
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198591
PNG
(US9216999, 384b | US9556187, Example 384b)
Show SMILES FC(F)(F)CNC(=O)CN[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C17H20F3N7O/c18-17(19,20)8-23-13(28)7-22-11-3-1-10(2-4-11)14-15-12-5-6-21-16(12)24-9-27(15)26-25-14/h5-6,9-11,21-22H,1-4,7-8H2,(H,23,28)/t10-,11-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198657
PNG
(US9216999, 385b | US9556187, Example 385b)
Show SMILES OC(CN[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12)(c1cccnc1)C(F)(F)F
Show InChI InChI=1S/C21H22F3N7O/c22-21(23,24)20(32,14-2-1-8-25-10-14)11-27-15-5-3-13(4-6-15)17-18-16-7-9-26-19(16)28-12-31(18)30-29-17/h1-2,7-10,12-13,15,26-27,32H,3-6,11H2/t13-,15-,20?
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198593
PNG
(US9216999, 386b | US9556187, Example 386b)
Show SMILES CSc1ccc(cc1)C(O)(CN[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12)C(F)(F)F
Show InChI InChI=1S/C23H25F3N6OS/c1-34-17-8-4-15(5-9-17)22(33,23(24,25)26)12-28-16-6-2-14(3-7-16)19-20-18-10-11-27-21(18)29-13-32(20)31-30-19/h4-5,8-11,13-14,16,27-28,33H,2-3,6-7,12H2,1H3/t14-,16-,22?
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198594
PNG
(US9216999, 387b | US9556187, Example 387b)
Show SMILES COc1ccc(cn1)C(O)(CN[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12)C(F)(F)F
Show InChI InChI=1S/C22H24F3N7O2/c1-34-17-7-4-14(10-27-17)21(33,22(23,24)25)11-28-15-5-2-13(3-6-15)18-19-16-8-9-26-20(16)29-12-32(19)31-30-18/h4,7-10,12-13,15,26,28,33H,2-3,5-6,11H2,1H3/t13-,15-,21?
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198595
PNG
(US9216999, 388b | US9556187, Example 388b)
Show SMILES COc1ccc(cc1)C(O)(CN[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12)C(F)(F)F
Show InChI InChI=1S/C23H25F3N6O2/c1-34-17-8-4-15(5-9-17)22(33,23(24,25)26)12-28-16-6-2-14(3-7-16)19-20-18-10-11-27-21(18)29-13-32(20)31-30-19/h4-5,8-11,13-14,16,27-28,33H,2-3,6-7,12H2,1H3/t14-,16-,22?
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198596
PNG
(US9216999, 389b | US9556187, Example 389b)
Show SMILES Fc1ccc(cc1)[C@@H]1C[C@H]1CN[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C23H25FN6/c24-17-5-1-14(2-6-17)20-11-16(20)12-26-18-7-3-15(4-8-18)21-22-19-9-10-25-23(19)27-13-30(22)29-28-21/h1-2,5-6,9-10,13,15-16,18,20,25-26H,3-4,7-8,11-12H2/t15-,16-,18-,20-/m0/s1
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198597
PNG
(US9216999, 390b | US9556187, Example 390b)
Show SMILES COc1ccc(cc1OC)C(O)(CN[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12)C(F)(F)F
Show InChI InChI=1S/C24H27F3N6O3/c1-35-18-8-5-15(11-19(18)36-2)23(34,24(25,26)27)12-29-16-6-3-14(4-7-16)20-21-17-9-10-28-22(17)30-13-33(21)32-31-20/h5,8-11,13-14,16,28-29,34H,3-4,6-7,12H2,1-2H3/t14-,16-,23?
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198598
PNG
(US9216999, 391b | US9556187, Example 391b)
Show SMILES N#Cc1ccc(CCN[C@H]2CC[C@@H](CC2)c2nnn3cnc4[nH]ccc4c23)cc1
Show InChI InChI=1S/C22H23N7/c23-13-16-3-1-15(2-4-16)9-11-24-18-7-5-17(6-8-18)20-21-19-10-12-25-22(19)26-14-29(21)28-27-20/h1-4,10,12,14,17-18,24-25H,5-9,11H2/t17-,18-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198599
PNG
(US9216999, 392b | US9556187, Example 392b)
Show SMILES C1CC1N[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C16H20N6/c1-3-11(19-12-5-6-12)4-2-10(1)14-15-13-7-8-17-16(13)18-9-22(15)21-20-14/h7-12,17,19H,1-6H2/t10-,11-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198600
PNG
(US9216999, 393b | US9556187, Example 393b)
Show SMILES N#CCN[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C15H17N7/c16-6-8-17-11-3-1-10(2-4-11)13-14-12-5-7-18-15(12)19-9-22(14)21-20-13/h5,7,9-11,17-18H,1-4,8H2/t10-,11-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198601
PNG
(US9216999, 394b | US9556187, Example 394b)
Show SMILES N#CCCN[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C16H19N7/c17-7-1-8-18-12-4-2-11(3-5-12)14-15-13-6-9-19-16(13)20-10-23(15)22-21-14/h6,9-12,18-19H,1-5,8H2/t11-,12-
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Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198602
PNG
(US9216999, 395b | US9556187, Example 395b)
Show SMILES FC(F)(F)CN[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C15H17F3N6/c16-15(17,18)7-20-10-3-1-9(2-4-10)12-13-11-5-6-19-14(11)21-8-24(13)23-22-12/h5-6,8-10,19-20H,1-4,7H2/t9-,10-
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n/an/a 2.20n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198603
PNG
(US9216999, 396b | US9556187, Example 396b)
Show SMILES C(N[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12)C1CC1
Show InChI InChI=1S/C17H22N6/c1-2-11(1)9-19-13-5-3-12(4-6-13)15-16-14-7-8-18-17(14)20-10-23(16)22-21-15/h7-8,10-13,18-19H,1-6,9H2/t12-,13-
PDB

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n/an/a 22n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198604
PNG
(US9216999, 397b | US9556187, Example 397b)
Show SMILES CN(C)[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C15H20N6/c1-20(2)11-5-3-10(4-6-11)13-14-12-7-8-16-15(12)17-9-21(14)19-18-13/h7-11,16H,3-6H2,1-2H3/t10-,11-
PDB

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n/an/a 23n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198605
PNG
(US9216999, 398b | US9556187, Example 398b)
Show SMILES CN[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C14H18N6/c1-15-10-4-2-9(3-5-10)12-13-11-6-7-16-14(11)17-8-20(13)19-18-12/h6-10,15-16H,2-5H2,1H3/t9-,10-
PDB

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n/an/a 29n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198606
PNG
(US9216999, 399b | US9556187, Example 399b)
Show SMILES FC(F)CN[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C15H18F2N6/c16-12(17)7-19-10-3-1-9(2-4-10)13-14-11-5-6-18-15(11)20-8-23(14)22-21-13/h5-6,8-10,12,18-19H,1-4,7H2/t9-,10-
PDB

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n/an/a 7.5n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198607
PNG
(US9216999, 400b | US9556187, Example 400b)
Show SMILES FC(F)(F)C(N[C@H]1CC[C@@H](CC1)c1nnn2cnc3[nH]ccc3c12)C(F)(F)F
Show InChI InChI=1S/C16H16F6N6/c17-15(18,19)14(16(20,21)22)25-9-3-1-8(2-4-9)11-12-10-5-6-23-13(10)24-7-28(12)27-26-11/h5-9,14,23,25H,1-4H2/t8-,9-
PDB

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n/an/a 42n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198608
PNG
(US9216999, 401 | US9556187, Example 401)
Show SMILES OC[C@H]1CC[C@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C14H17N5O/c20-7-9-1-3-10(4-2-9)12-13-11-5-6-15-14(11)16-8-19(13)18-17-12/h5-6,8-10,15,20H,1-4,7H2/t9-,10+
PDB

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n/an/a 12n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198609
PNG
(US9216999, 402 | US9556187, Example 402)
Show SMILES O=C[C@H]1CC[C@H](CC1)c1nnn2cnc3[nH]ccc3c12
Show InChI InChI=1S/C14H15N5O/c20-7-9-1-3-10(4-2-9)12-13-11-5-6-15-14(11)16-8-19(13)18-17-12/h5-10,15H,1-4H2/t9-,10+
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n/an/a 11n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198610
PNG
(US9216999, 403 | US9556187, Example 403)
Show SMILES OC1CN(C[C@H]2CC[C@H](CC2)c2nnn3cnc4[nH]ccc4c23)C1
Show InChI InChI=1S/C17H22N6O/c24-13-8-22(9-13)7-11-1-3-12(4-2-11)15-16-14-5-6-18-17(14)19-10-23(16)21-20-15/h5-6,10-13,18,24H,1-4,7-9H2/t11-,12+
PDB

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n/an/a 40n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198611
PNG
(US9216999, 404 | US9556187, Example 404)
Show SMILES O[C@H]1CCN(C[C@H]2CC[C@H](CC2)c2nnn3cnc4[nH]ccc4c23)C1
Show InChI InChI=1S/C18H24N6O/c25-14-6-8-23(10-14)9-12-1-3-13(4-2-12)16-17-15-5-7-19-18(15)20-11-24(17)22-21-16/h5,7,11-14,19,25H,1-4,6,8-10H2/t12-,13+,14-/m0/s1
PDB

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n/an/a 110n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
Tyrosine-protein kinase JAK1


(Homo sapiens (Human))
BDBM198612
PNG
(US9216999, 405 | US9556187, Example 405)
Show SMILES O[C@@H]1CCN(C[C@H]2CC[C@H](CC2)c2nnn3cnc4[nH]ccc4c23)C1
Show InChI InChI=1S/C18H24N6O/c25-14-6-8-23(10-14)9-12-1-3-13(4-2-12)16-17-15-5-7-19-18(15)20-11-24(17)22-21-16/h5,7,11-14,19,25H,1-4,6,8-10H2/t12-,13+,14-/m1/s1
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n/an/a 25n/an/an/an/a7.5n/a



Nissan Chemical Industries, Ltd.

US Patent


Assay Description
JAK1, JAK2, JAK3 and Tyk2 were purchased from Carna Biosciences, Inc. As the substrate, LANCE Ultra ULight-JAK1 Peptide (manufactured by PerkinElmer ...


US Patent US9216999 (2015)


BindingDB Entry DOI: 10.7270/Q28C9V2J
More data for this
Ligand-Target Pair
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