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Compile Data Set for Download or QSAR

Found 74 hits Enz. Inhib. hit(s) with Target = 'Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53441
PNG
(MLS001000876 | N-(1H-benzimidazol-2-yl)-3-chlorany...)
Show SMILES Clc1cccc(c1)C(=O)Nc1nc2ccccc2[nH]1
Show InChI InChI=1S/C14H10ClN3O/c15-10-5-3-4-9(8-10)13(19)18-14-16-11-6-1-2-7-12(11)17-14/h1-8H,(H2,16,17,18,19)
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400 -36.5 880n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53413
PNG
((2S)-2-[[[4-[(4-methylanilino)-oxomethyl]-1H-imida...)
Show SMILES Cc1ccc(NC(=O)c2[nH]cnc2C(=O)N[C@@H](CCCCNC(=O)OC(C)(C)C)C(=O)OC(C)(C)C)cc1
Show InChI InChI=1S/C27H39N5O6/c1-17-11-13-18(14-12-17)31-22(33)20-21(30-16-29-20)23(34)32-19(24(35)37-26(2,3)4)10-8-9-15-28-25(36)38-27(5,6)7/h11-14,16,19H,8-10,15H2,1-7H3,(H,28,36)(H,29,30)(H,31,33)(H,32,34)/t19-/m0/s1
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n/an/a 6.00E+3n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53414
PNG
((2S)-4-methyl-2-[[4-(m-tolylcarbamoyl)-1H-imidazol...)
Show SMILES CC(C)C[C@H](NC(=O)c1nc[nH]c1C(=O)Nc1cccc(C)c1)C(=O)OCc1ccccc1
Show InChI InChI=1S/C25H28N4O4/c1-16(2)12-20(25(32)33-14-18-9-5-4-6-10-18)29-24(31)22-21(26-15-27-22)23(30)28-19-11-7-8-17(3)13-19/h4-11,13,15-16,20H,12,14H2,1-3H3,(H,26,27)(H,28,30)(H,29,31)/t20-/m0/s1
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n/an/a 1.20E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53415
PNG
((2S)-2-[[4-(m-tolylcarbamoyl)-1H-imidazole-5-carbo...)
Show SMILES Cc1cccc(NC(=O)c2nc[nH]c2C(=O)N[C@@H](Cc2ccccc2)C(=O)OC(C)(C)C)c1
Show InChI InChI=1S/C25H28N4O4/c1-16-9-8-12-18(13-16)28-22(30)20-21(27-15-26-20)23(31)29-19(24(32)33-25(2,3)4)14-17-10-6-5-7-11-17/h5-13,15,19H,14H2,1-4H3,(H,26,27)(H,28,30)(H,29,31)/t19-/m0/s1
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n/an/a 1.20E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53416
PNG
((2S)-2-[[4-[(4-chlorophenyl)carbamoyl]-1H-imidazol...)
Show SMILES CC(C)(C)OC(=O)[C@H](Cc1ccccc1)NC(=O)c1[nH]cnc1C(=O)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C24H25ClN4O4/c1-24(2,3)33-23(32)18(13-15-7-5-4-6-8-15)29-22(31)20-19(26-14-27-20)21(30)28-17-11-9-16(25)10-12-17/h4-12,14,18H,13H2,1-3H3,(H,26,27)(H,28,30)(H,29,31)/t18-/m0/s1
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n/an/a 1.60E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53417
PNG
((2S)-2-[[4-[(3-chlorophenyl)carbamoyl]-1H-imidazol...)
Show SMILES CC(C)(C)OC(=O)[C@H](Cc1ccccc1)NC(=O)c1[nH]cnc1C(=O)Nc1cccc(Cl)c1
Show InChI InChI=1S/C24H25ClN4O4/c1-24(2,3)33-23(32)18(12-15-8-5-4-6-9-15)29-22(31)20-19(26-14-27-20)21(30)28-17-11-7-10-16(25)13-17/h4-11,13-14,18H,12H2,1-3H3,(H,26,27)(H,28,30)(H,29,31)/t18-/m0/s1
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n/an/a 1.70E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53418
PNG
((2S)-2-[[[4-[(4-chloroanilino)-oxomethyl]-1H-imida...)
Show SMILES CC(C)(C)OC(=O)NCCCC[C@H](NC(=O)c1nc[nH]c1C(=O)Nc1ccc(Cl)cc1)C(=O)OC(C)(C)C
Show InChI InChI=1S/C26H36ClN5O6/c1-25(2,3)37-23(35)18(9-7-8-14-28-24(36)38-26(4,5)6)32-22(34)20-19(29-15-30-20)21(33)31-17-12-10-16(27)11-13-17/h10-13,15,18H,7-9,14H2,1-6H3,(H,28,36)(H,29,30)(H,31,33)(H,32,34)/t18-/m0/s1
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n/an/a 1.90E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53419
PNG
((2S)-2-[[4-[(4-methoxyphenyl)carbamoyl]-1H-imidazo...)
Show SMILES COc1ccc(NC(=O)c2[nH]cnc2C(=O)N[C@@H](CC(C)C)C(=O)OC(C)(C)C)cc1
Show InChI InChI=1S/C22H30N4O5/c1-13(2)11-16(21(29)31-22(3,4)5)26-20(28)18-17(23-12-24-18)19(27)25-14-7-9-15(30-6)10-8-14/h7-10,12-13,16H,11H2,1-6H3,(H,23,24)(H,25,27)(H,26,28)/t16-/m0/s1
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n/an/a 2.70E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53420
PNG
((4S,5S,6R)-1-benzyl-2-keto-6-methyl-4-phenethyl-he...)
Show SMILES COC(=O)[C@H]1[C@H](CCc2ccccc2)NC(=O)N(Cc2ccccc2)[C@@H]1C
Show InChI InChI=1S/C22H26N2O3/c1-16-20(21(25)27-2)19(14-13-17-9-5-3-6-10-17)23-22(26)24(16)15-18-11-7-4-8-12-18/h3-12,16,19-20H,13-15H2,1-2H3,(H,23,26)/t16-,19+,20-/m1/s1
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n/an/a 5.10E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM24778
PNG
(2-methyl-1,4-dihydronaphthalene-1,4-dione | 2-meth...)
Show SMILES CC1=CC(=O)c2ccccc2C1=O
Show InChI InChI=1S/C11H8O2/c1-7-6-10(12)8-4-2-3-5-9(8)11(7)13/h2-6H,1H3
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n/an/a 2.90E+5n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53422
PNG
(2,4-Dicyclohexyl-6-methoxy-quinazoline | 2,4-dicyc...)
Show SMILES COc1ccc2nc(nc(C3CCCCC3)c2c1)C1CCCCC1
Show InChI InChI=1S/C21H28N2O/c1-24-17-12-13-19-18(14-17)20(15-8-4-2-5-9-15)23-21(22-19)16-10-6-3-7-11-16/h12-16H,2-11H2,1H3
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n/an/a 1.26E+5n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53421
PNG
(4-Cyclohexyl-2-phenyl-quinazoline | 4-cyclohexyl-2...)
Show SMILES C1CCC(CC1)c1nc(nc2ccccc12)-c1ccccc1
Show InChI InChI=1S/C20H20N2/c1-3-9-15(10-4-1)19-17-13-7-8-14-18(17)21-20(22-19)16-11-5-2-6-12-16/h2,5-8,11-15H,1,3-4,9-10H2
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n/an/a 7.50E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53423
PNG
(1,3,5,6-tetrahydroxy-4-(2-methylbut-3-en-2-yl)-2-(...)
Show SMILES CC(C)=CCc1c(O)c(c2oc3c(O)c(O)ccc3c(=O)c2c1O)C(C)(C)C=C
Show InChI InChI=1S/C23H24O6/c1-6-23(4,5)16-19(27)12(8-7-11(2)3)17(25)15-18(26)13-9-10-14(24)20(28)21(13)29-22(15)16/h6-7,9-10,24-25,27-28H,1,8H2,2-5H3
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n/an/a 1.80E+3n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53424
PNG
((1R,12bR)-1,2,3,4,6,7,12,12b-octahydroindolo[2,3-a...)
Show SMILES O[C@@H]1CCCN2CCc3c([nH]c4ccccc34)[C@H]12
Show InChI InChI=1S/C15H18N2O/c18-13-6-3-8-17-9-7-11-10-4-1-2-5-12(10)16-14(11)15(13)17/h1-2,4-5,13,15-16,18H,3,6-9H2/t13-,15+/m1/s1
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n/an/a 3.40E+3n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53425
PNG
(2,3,3-trimethyl-4,8,9-tris(oxidanyl)-2H-furo[3,2-b...)
Show SMILES CC1Oc2cc3oc4c(O)c(O)ccc4c(=O)c3c(O)c2C1(C)C
Show InChI InChI=1S/C18H16O6/c1-7-18(2,3)13-11(23-7)6-10-12(16(13)22)14(20)8-4-5-9(19)15(21)17(8)24-10/h4-7,19,21-22H,1-3H3
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n/an/a 3.40E+3n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53426
PNG
(Acylated oxime isatin derivative, 15 | MLS00069763...)
Show SMILES CC1Oc2cc3oc4c(O)c5OC(C)(C)C=Cc5cc4c(=O)c3c(O)c2C1(C)C
Show InChI InChI=1S/C23H22O6/c1-10-23(4,5)16-14(27-10)9-13-15(18(16)25)17(24)12-8-11-6-7-22(2,3)29-20(11)19(26)21(12)28-13/h6-10,25-26H,1-5H3
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n/an/a 4.10E+3n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53427
PNG
(4-[(3R)-8,8-dimethyl-3,4-dihydro-2H-pyrano[2,3-f][...)
Show SMILES CC(C)=CCc1cc([C@@H]2COc3c(C2)ccc2OC(C)(C)C=Cc32)c(O)cc1O
Show InChI InChI=1S/C25H28O4/c1-15(2)5-6-16-12-20(22(27)13-21(16)26)18-11-17-7-8-23-19(24(17)28-14-18)9-10-25(3,4)29-23/h5,7-10,12-13,18,26-27H,6,11,14H2,1-4H3/t18-/m0/s1
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n/an/a 6.10E+3n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53428
PNG
(2-[(3R)-8,8-dimethyl-3,4-dihydro-2H-pyrano[2,3-f][...)
Show SMILES CC(C)=CCOc1ccc([C@@H]2COc3c(C2)ccc2OC(C)(C)C=Cc32)c(O)c1
Show InChI InChI=1S/C25H28O4/c1-16(2)10-12-27-19-6-7-20(22(26)14-19)18-13-17-5-8-23-21(24(17)28-15-18)9-11-25(3,4)29-23/h5-11,14,18,26H,12-13,15H2,1-4H3/t18-/m0/s1
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n/an/a 8.80E+3n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53429
PNG
(Acylated oxime isatin derivative, 18 | MLS00069758...)
Show SMILES CC(C)=CCc1c2OC(C)(C)C=Cc2c(O)c2c1oc1-c3cc(O)c(O)cc3OC(C=C(C)C)c1c2=O
Show InChI InChI=1S/C30H30O7/c1-14(2)7-8-17-27-16(9-10-30(5,6)37-27)25(33)24-26(34)23-22(11-15(3)4)35-21-13-20(32)19(31)12-18(21)29(23)36-28(17)24/h7,9-13,22,31-33H,8H2,1-6H3
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n/an/a 1.20E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53430
PNG
(Acylated oxime isatin derivative, 19)
Show InChI InChI=1S/C10H18O/c1-9(2)8-4-6-10(3,11-9)7-5-8/h8H,4-7H2,1-3H3
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n/an/a 1.80E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53431
PNG
(2-(3-methylphenoxy)-N-(4-pyridinyl)acetamide | 2-(...)
Show SMILES Cc1cccc(OCC(=O)Nc2ccncc2)c1
Show InChI InChI=1S/C14H14N2O2/c1-11-3-2-4-13(9-11)18-10-14(17)16-12-5-7-15-8-6-12/h2-9H,10H2,1H3,(H,15,16,17)
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n/an/a 3.60E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53432
PNG
(4-(4-bromophenyl)-2-[(2-fluorobenzoyl)amino]-3-the...)
Show SMILES OC(=O)c1c(NC(=O)c2ccccc2F)scc1-c1ccc(Br)cc1
Show InChI InChI=1S/C18H11BrFNO3S/c19-11-7-5-10(6-8-11)13-9-25-17(15(13)18(23)24)21-16(22)12-3-1-2-4-14(12)20/h1-9H,(H,21,22)(H,23,24)
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n/an/a 1.20E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53433
PNG
(2-[(4-tert-butylbenzoyl)amino]-4-(4-methoxyphenyl)...)
Show SMILES COc1ccc(cc1)-c1csc(NC(=O)c2ccc(cc2)C(C)(C)C)c1C(O)=O
Show InChI InChI=1S/C23H23NO4S/c1-23(2,3)16-9-5-15(6-10-16)20(25)24-21-19(22(26)27)18(13-29-21)14-7-11-17(28-4)12-8-14/h5-13H,1-4H3,(H,24,25)(H,26,27)
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n/an/a 2.20E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53434
PNG
(4-(1-piperidinyl)-1,2-naphthalenedione | 4-(1-pipe...)
Show SMILES O=C1C=C(N2CCCCC2)c2ccccc2C1=O
Show InChI InChI=1S/C15H15NO2/c17-14-10-13(16-8-4-1-5-9-16)11-6-2-3-7-12(11)15(14)18/h2-3,6-7,10H,1,4-5,8-9H2
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n/an/a 7.80E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53435
PNG
((1S,2S,5R)-4,6,6-trimethyl-2-(2,4,6-trimethoxyphen...)
Show SMILES COc1cc(OC)c([C@H]2C=C(C)[C@H]3C[C@@H]2C3(C)C)c(OC)c1
Show InChI InChI=1S/C19H26O3/c1-11-7-13(15-10-14(11)19(15,2)3)18-16(21-5)8-12(20-4)9-17(18)22-6/h7-9,13-15H,10H2,1-6H3/t13-,14+,15-/m0/s1
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n/an/a 8.00E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53436
PNG
(2-[4-[[5-(4-chlorophenyl)-6-ethoxycarbonyl-7-methy...)
Show SMILES CCOC(=O)C1=C(C)N=c2sc(=Cc3ccc(OCC(O)=O)c(OC)c3)c(=O)n2C1c1ccc(Cl)cc1
Show InChI InChI=1S/C26H23ClN2O7S/c1-4-35-25(33)22-14(2)28-26-29(23(22)16-6-8-17(27)9-7-16)24(32)20(37-26)12-15-5-10-18(19(11-15)34-3)36-13-21(30)31/h5-12,23H,4,13H2,1-3H3,(H,30,31)
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n/an/a 4.30E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53437
PNG
(1,3-bis(4-methoxy-2,6-dimethyl-phenyl)propane-1,3-...)
Show SMILES COc1cc(C)c(C(=O)CC(=O)c2c(C)cc(OC)cc2C)c(C)c1
Show InChI InChI=1S/C21H24O4/c1-12-7-16(24-5)8-13(2)20(12)18(22)11-19(23)21-14(3)9-17(25-6)10-15(21)4/h7-10H,11H2,1-6H3
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n/an/a 4.50E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53438
PNG
(4-bromanyl-2,6-diphenyl-pyrimidine | 4-bromo-2,6-d...)
Show SMILES Brc1cc(nc(n1)-c1ccccc1)-c1ccccc1
Show InChI InChI=1S/C16H11BrN2/c17-15-11-14(12-7-3-1-4-8-12)18-16(19-15)13-9-5-2-6-10-13/h1-11H
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n/an/a 1.30E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53439
PNG
(1-(3-chloro-8-fluoro-10,11-dihydrodibenzo[b,f]thie...)
Show SMILES CN1CCN(CC1)C1Cc2ccc(Cl)cc2Sc2ccc(F)cc12
Show InChI InChI=1S/C19H20ClFN2S/c1-22-6-8-23(9-7-22)17-10-13-2-3-14(20)11-19(13)24-18-5-4-15(21)12-16(17)18/h2-5,11-12,17H,6-10H2,1H3
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n/an/a 3.21E+5n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53440
PNG
(2-(4-methoxybenzyl)naphthoquinone | 2-[(4-methoxyp...)
Show SMILES COc1ccc(CC2=CC(=O)c3ccccc3C2=O)cc1
Show InChI InChI=1S/C18H14O3/c1-21-14-8-6-12(7-9-14)10-13-11-17(19)15-4-2-3-5-16(15)18(13)20/h2-9,11H,10H2,1H3
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n/an/a 1.14E+5n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53442
PNG
((7-chloranyl-3,5-dimethyl-1-benzofuran-2-yl)-(4-ox...)
Show SMILES Cc1c(oc2c(Cl)cc(C)cc12)C(=O)N1CCC(O)(CC1)c1ccccc1
Show InChI InChI=1S/C22H22ClNO3/c1-14-12-17-15(2)19(27-20(17)18(23)13-14)21(25)24-10-8-22(26,9-11-24)16-6-4-3-5-7-16/h3-7,12-13,26H,8-11H2,1-2H3
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n/an/a 1.20E+3n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53443
PNG
(2-(3-chloro-4-methoxy-N-methylsulfonylanilino)-N-[...)
Show SMILES COc1ccc(cc1Cl)N(CC(=O)NCCSCc1cccc(Cl)c1)S(C)(=O)=O
Show InChI InChI=1S/C19H22Cl2N2O4S2/c1-27-18-7-6-16(11-17(18)21)23(29(2,25)26)12-19(24)22-8-9-28-13-14-4-3-5-15(20)10-14/h3-7,10-11H,8-9,12-13H2,1-2H3,(H,22,24)
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n/an/a 1.30E+3n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53444
PNG
(3,5-dimethyl-4-[4-(4-methylphenoxy)butyl]-1H-pyraz...)
Show SMILES Cc1n[nH]c(C)c1CCCCOc1ccc(C)cc1
Show InChI InChI=1S/C16H22N2O/c1-12-7-9-15(10-8-12)19-11-5-4-6-16-13(2)17-18-14(16)3/h7-10H,4-6,11H2,1-3H3,(H,17,18)
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n/an/a 1.30E+3n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53445
PNG
(2-(4-hydroxy-3-nitro-benzylidene)-3-keto-5-(2-meth...)
Show SMILES CCOC(=O)C1=C(C)N=c2s\c(=C/c3ccc(O)c(c3)[N+]([O-])=O)c(=O)n2C1c1ccccc1OC
Show InChI InChI=1S/C24H21N3O7S/c1-4-34-23(30)20-13(2)25-24-26(21(20)15-7-5-6-8-18(15)33-3)22(29)19(35-24)12-14-9-10-17(28)16(11-14)27(31)32/h5-12,21,28H,4H2,1-3H3/b19-12-
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n/an/a 1.80E+3n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53446
PNG
(1-isopropyl-3-trityl-thiourea | 1-propan-2-yl-3-(t...)
Show SMILES CC(C)NC(=S)NC(c1ccccc1)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C23H24N2S/c1-18(2)24-22(26)25-23(19-12-6-3-7-13-19,20-14-8-4-9-15-20)21-16-10-5-11-17-21/h3-18H,1-2H3,(H2,24,25,26)
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n/an/a 2.70E+3n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53447
PNG
(4,4'-[1,4-phenylenebis(oxy)]diphenol | 4-[4-(4...)
Show SMILES Oc1ccc(Oc2ccc(Oc3ccc(O)cc3)cc2)cc1
Show InChI InChI=1S/C18H14O4/c19-13-1-5-15(6-2-13)21-17-9-11-18(12-10-17)22-16-7-3-14(20)4-8-16/h1-12,19-20H
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n/an/a 3.40E+3n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53448
PNG
(1-methyl-1-[4-(4-methylphenyl)-6-phenyl-2-pyrimidi...)
Show SMILES CN(N)c1nc(cc(n1)-c1ccc(C)cc1)-c1ccccc1
Show InChI InChI=1S/C18H18N4/c1-13-8-10-15(11-9-13)17-12-16(14-6-4-3-5-7-14)20-18(21-17)22(2)19/h3-12H,19H2,1-2H3
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n/an/a 4.10E+3n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53449
PNG
(4-(4-bromophenyl)-2-(o-toluoylamino)-3-thenoic aci...)
Show SMILES Cc1ccccc1C(=O)Nc1scc(c1C(O)=O)-c1ccc(Br)cc1
Show InChI InChI=1S/C19H14BrNO3S/c1-11-4-2-3-5-14(11)17(22)21-18-16(19(23)24)15(10-25-18)12-6-8-13(20)9-7-12/h2-10H,1H3,(H,21,22)(H,23,24)
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n/an/a 6.00E+3n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53450
PNG
(4-(4-bromophenyl)-2-(m-toluoylamino)-3-thenoic aci...)
Show SMILES Cc1cccc(c1)C(=O)Nc1scc(c1C(O)=O)-c1ccc(Br)cc1
Show InChI InChI=1S/C19H14BrNO3S/c1-11-3-2-4-13(9-11)17(22)21-18-16(19(23)24)15(10-25-18)12-5-7-14(20)8-6-12/h2-10H,1H3,(H,21,22)(H,23,24)
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n/an/a 6.20E+3n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53451
PNG
(MLS001163735 | N-(1-adamantyl)-5-nitro-2-furamide ...)
Show SMILES [O-][N+](=O)c1ccc(o1)C(=O)NC12CC3CC(CC(C3)C1)C2
Show InChI InChI=1S/C15H18N2O4/c18-14(12-1-2-13(21-12)17(19)20)16-15-6-9-3-10(7-15)5-11(4-9)8-15/h1-2,9-11H,3-8H2,(H,16,18)
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n/an/a 6.50E+3n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53452
PNG
(2-[4-(4-Fluoro-phenyl)-thiazol-2-ylamino]-2-[1-(4-...)
Show SMILES Cc1ccc(Cn2c(nc3ccccc23)C(CO)Nc2nc(cs2)-c2ccc(F)cc2)cc1
Show InChI InChI=1S/C26H23FN4OS/c1-17-6-8-18(9-7-17)14-31-24-5-3-2-4-21(24)28-25(31)22(15-32)29-26-30-23(16-33-26)19-10-12-20(27)13-11-19/h2-13,16,22,32H,14-15H2,1H3,(H,29,30)
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n/an/a 8.80E+3n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53453
PNG
(2-hydroxy-N''''-[(E)-(3-nitro-6-oxo-1-cyclohexa-2,...)
Show SMILES OC(C(=O)N\[NH+]=C\[c-]1cc(ccc1=O)[N+]([O-])=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C21H16N3O5/c25-19-12-11-18(24(28)29)13-15(19)14-22-23-20(26)21(27,16-7-3-1-4-8-16)17-9-5-2-6-10-17/h1-14,27H,(H,23,26)/q-1/p+1/b22-14+
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n/an/a 9.50E+3n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53454
PNG
((2E)-2-[(2Z)-2-(3-methoxy-4-oxidanylidene-cyclohex...)
Show SMILES COc1ccc(cc1)-n1c(C=Cc2ccc(O)c(OC)c2)nc2ccccc2c1=O
Show InChI InChI=1S/C24H20N2O4/c1-29-18-11-9-17(10-12-18)26-23(25-20-6-4-3-5-19(20)24(26)28)14-8-16-7-13-21(27)22(15-16)30-2/h3-15,27H,1-2H3
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n/an/a 1.20E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53455
PNG
((6E)-6-[(4-methoxyphenyl)hydrazinylidene]-4-phenyl...)
Show SMILES COc1ccc(cc1)N=Nc1cc(ccc1O)-c1ccccc1
Show InChI InChI=1S/C19H16N2O2/c1-23-17-10-8-16(9-11-17)20-21-18-13-15(7-12-19(18)22)14-5-3-2-4-6-14/h2-13,22H,1H3
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n/an/a 1.20E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53456
PNG
(3-phenyl-4-[(4-propan-2-ylphenyl)methylideneamino]...)
Show SMILES CC(C)c1ccc(C=Nn2c(n[nH]c2=S)-c2ccccc2)cc1
Show InChI InChI=1S/C18H18N4S/c1-13(2)15-10-8-14(9-11-15)12-19-22-17(20-21-18(22)23)16-6-4-3-5-7-16/h3-13H,1-2H3,(H,21,23)
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n/an/a 1.30E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53457
PNG
(2,4-bis(bromanyl)-6-[(quinolin-8-ylamino)methyl]ph...)
Show SMILES Oc1c(Br)cc(Br)cc1CNc1cccc2cccnc12
Show InChI InChI=1S/C16H12Br2N2O/c17-12-7-11(16(21)13(18)8-12)9-20-14-5-1-3-10-4-2-6-19-15(10)14/h1-8,20-21H,9H2
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n/an/a 1.40E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53041
PNG
(MLS001181166 | N''''-[(E)-(3-chloranyl-5-nitro-6-o...)
Show SMILES OC(C(=O)N\[NH+]=C\[c-]1cc(Cl)cc([N+]([O-])=O)c1=O)(c1ccccc1)c1ccccc1
Show InChI InChI=1S/C21H15ClN3O5/c22-17-11-14(19(26)18(12-17)25(29)30)13-23-24-20(27)21(28,15-7-3-1-4-8-15)16-9-5-2-6-10-16/h1-13,28H,(H,24,27)/q-1/p+1/b23-13+
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n/an/a 1.60E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53459
PNG
((5E)-3-benzyl-2-thioxo-5-vanillylidene-thiazolidin...)
Show SMILES COc1cc(\C=C2\SC(=S)N(Cc3ccccc3)C2=O)ccc1O
Show InChI InChI=1S/C18H15NO3S2/c1-22-15-9-13(7-8-14(15)20)10-16-17(21)19(18(23)24-16)11-12-5-3-2-4-6-12/h2-10,20H,11H2,1H3/b16-10+
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n/an/a 1.80E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53460
PNG
(1-[2-(2-Isopropyl-4-methyl-phenoxy)-ethyl]-1H-benz...)
Show SMILES CC(C)c1cc(C)ccc1OCCn1c2ccccc2[nH]c1=S
Show InChI InChI=1S/C19H22N2OS/c1-13(2)15-12-14(3)8-9-18(15)22-11-10-21-17-7-5-4-6-16(17)20-19(21)23/h4-9,12-13H,10-11H2,1-3H3,(H,20,23)
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n/an/a 1.90E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
Ubiquitin carboxyl-terminal hydrolase isozyme L1 (UCH-L1)


(Mus musculus (Mouse))
BDBM53461
PNG
((6E)-3-ethoxy-6-[[2-(2-methyl-6-morpholin-4-yl-pyr...)
Show SMILES CCOc1ccc(CN=Nc2cc(nc(C)n2)N2CCOCC2)c(O)c1
Show InChI InChI=1S/C18H23N5O3/c1-3-26-15-5-4-14(16(24)10-15)12-19-22-17-11-18(21-13(2)20-17)23-6-8-25-9-7-23/h4-5,10-11,24H,3,6-9,12H2,1-2H3
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n/an/a 1.90E+4n/an/an/an/a7.625



Brigham and Women's Hospital



Assay Description
Inhibition activity and selectivity for UCH-L1 and UCH-L3.


Chem Biol 10: 837-46 (2003)


Article DOI: 10.1016/j.chembiol.2003.08.010
BindingDB Entry DOI: 10.7270/Q20Z71P9
More data for this
Ligand-Target Pair
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