BindingDB logo
myBDB logout
Compile Data Set for Download or QSAR

Found 549 hits Enz. Inhib. hit(s) with Target = 'alpha-Glucosidase (α-Glucosidase)'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM222410
PNG
(3-(1-Naphthyl-1H-[1,2,3]triazol-4-yl)-N-(2,3,4,6-t...)
Show SMILES OCC1O[C@@H](NC(=O)CCc2cn(nn2)-c2ccc3ccccc3c2)C(O)C(O)[C@@H]1O
Show InChI InChI=1S/C21H24N4O6/c26-11-16-18(28)19(29)20(30)21(31-16)22-17(27)8-6-14-10-25(24-23-14)15-7-5-12-3-1-2-4-13(12)9-15/h1-5,7,9-10,16,18-21,26,28-30H,6,8,11H2,(H,22,27)/t16?,18-,19?,20?,21-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.57E+5n/an/an/an/a6.81



CSIR-Indian Institute of Chemical Biology



Assay Description
Briefly, the sample solution (25 μL, 1.0 mM solution in DMSO) was mixed with enzyme solution (25 μL, 0.5 U/mL prepared in 0.1 M phosphate buffe...


Bioorg Chem 72: 11-20 (2017)


Article DOI: 10.1016/j.bioorg.2017.03.006
BindingDB Entry DOI: 10.7270/Q2D7999X
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM222411
PNG
(3-[1-(2,5-Dimethoxyphenyl)-1H-[1,2,3]triazol-4-yl]...)
Show SMILES COc1ccc(OC)c(c1)-n1cc(CCC(=O)N[C@@H]2OC(CO)[C@@H](O)C(O)C2O)nn1
Show InChI InChI=1S/C19H26N4O8/c1-29-11-4-5-13(30-2)12(7-11)23-8-10(21-22-23)3-6-15(25)20-19-18(28)17(27)16(26)14(9-24)31-19/h4-5,7-8,14,16-19,24,26-28H,3,6,9H2,1-2H3,(H,20,25)/t14?,16-,17?,18?,19-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.28E+5n/an/an/an/a6.81



CSIR-Indian Institute of Chemical Biology



Assay Description
Briefly, the sample solution (25 μL, 1.0 mM solution in DMSO) was mixed with enzyme solution (25 μL, 0.5 U/mL prepared in 0.1 M phosphate buffe...


Bioorg Chem 72: 11-20 (2017)


Article DOI: 10.1016/j.bioorg.2017.03.006
BindingDB Entry DOI: 10.7270/Q2D7999X
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM222412
PNG
(3-[1-(3,4, 5-trimethoxyphenyl)-1H-[1,2,3]triazol-4...)
Show SMILES COc1cc(cc(OC)c1OC)-n1cc(CCC(=O)N[C@@H]2OC(CO)[C@@H](O)C(O)C2O)nn1
Show InChI InChI=1S/C20H28N4O9/c1-30-12-6-11(7-13(31-2)19(12)32-3)24-8-10(22-23-24)4-5-15(26)21-20-18(29)17(28)16(27)14(9-25)33-20/h6-8,14,16-18,20,25,27-29H,4-5,9H2,1-3H3,(H,21,26)/t14?,16-,17?,18?,20-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.21E+5n/an/an/an/a6.81



CSIR-Indian Institute of Chemical Biology



Assay Description
Briefly, the sample solution (25 μL, 1.0 mM solution in DMSO) was mixed with enzyme solution (25 μL, 0.5 U/mL prepared in 0.1 M phosphate buffe...


Bioorg Chem 72: 11-20 (2017)


Article DOI: 10.1016/j.bioorg.2017.03.006
BindingDB Entry DOI: 10.7270/Q2D7999X
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM23406
PNG
((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Show SMILES C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)OC(O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23?,24-,25-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 1.31E+5n/an/an/an/a6.81



CSIR-Indian Institute of Chemical Biology



Assay Description
Briefly, the sample solution (25 μL, 1.0 mM solution in DMSO) was mixed with enzyme solution (25 μL, 0.5 U/mL prepared in 0.1 M phosphate buffe...


Bioorg Chem 72: 11-20 (2017)


Article DOI: 10.1016/j.bioorg.2017.03.006
BindingDB Entry DOI: 10.7270/Q2D7999X
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Saccharomyces cerevisiae (Baker's yeast))
BDBM231682
PNG
(3-(4-(1-(4-Chlorophenyl)-4,5-diphenyl-1H-imidazol-...)
Show SMILES Clc1ccc(cc1)-n1c(nc(c1-c1ccccc1)-c1ccccc1)-c1cn(nc1C1=CC2C=CC=CC2OC1=O)-c1ccccc1
Show InChI InChI=1S/C39H27ClN4O2/c40-29-20-22-31(23-21-29)44-37(27-14-6-2-7-15-27)35(26-12-4-1-5-13-26)41-38(44)33-25-43(30-17-8-3-9-18-30)42-36(33)32-24-28-16-10-11-19-34(28)46-39(32)45/h1-25,28,34H
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.27E+4n/an/an/an/a6.837



Kinnaird College for Women



Assay Description
For α-glucosidase inhibition assay, α-glucosidase enzyme (Cat No. 5003-1KU Type I; isolated from Saccharomyces cereviciae) was used. Acarbo...


Bioorg Chem 73: 1-9 (2017)


Article DOI: 10.1016/j.bioorg.2017.05.009
BindingDB Entry DOI: 10.7270/Q2TD9W62
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Saccharomyces cerevisiae (Baker's yeast))
BDBM231683
PNG
(3-(4-(1-(4-Bromophenyl)-4,5-diphenyl-1H-imidazol-2...)
Show SMILES Brc1ccc(cc1)-n1c(nc(c1-c1ccccc1)-c1ccccc1)-c1cn(nc1C1=CC2C=CC=CC2OC1=O)-c1ccccc1
Show InChI InChI=1S/C39H27BrN4O2/c40-29-20-22-31(23-21-29)44-37(27-14-6-2-7-15-27)35(26-12-4-1-5-13-26)41-38(44)33-25-43(30-17-8-3-9-18-30)42-36(33)32-24-28-16-10-11-19-34(28)46-39(32)45/h1-25,28,34H
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.44E+4n/an/an/an/a6.837



Kinnaird College for Women



Assay Description
For α-glucosidase inhibition assay, α-glucosidase enzyme (Cat No. 5003-1KU Type I; isolated from Saccharomyces cereviciae) was used. Acarbo...


Bioorg Chem 73: 1-9 (2017)


Article DOI: 10.1016/j.bioorg.2017.05.009
BindingDB Entry DOI: 10.7270/Q2TD9W62
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Saccharomyces cerevisiae (Baker's yeast))
BDBM231684
PNG
(3-(4-(1-(4-Methoxyphenyl)-4,5-diphenyl-1H-imidazol...)
Show SMILES COc1ccc(cc1)-n1c(nc(c1-c1ccccc1)-c1ccccc1)-c1cn(nc1C1=CC2C=CC=CC2OC1=O)-c1ccccc1
Show InChI InChI=1S/C40H30N4O3/c1-46-32-23-21-31(22-24-32)44-38(28-15-7-3-8-16-28)36(27-13-5-2-6-14-27)41-39(44)34-26-43(30-18-9-4-10-19-30)42-37(34)33-25-29-17-11-12-20-35(29)47-40(33)45/h2-26,29,35H,1H3
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.54E+4n/an/an/an/a6.837



Kinnaird College for Women



Assay Description
For α-glucosidase inhibition assay, α-glucosidase enzyme (Cat No. 5003-1KU Type I; isolated from Saccharomyces cereviciae) was used. Acarbo...


Bioorg Chem 73: 1-9 (2017)


Article DOI: 10.1016/j.bioorg.2017.05.009
BindingDB Entry DOI: 10.7270/Q2TD9W62
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Saccharomyces cerevisiae (Baker's yeast))
BDBM231685
PNG
(3-(4-(1-(3,5-Dimethylphenyl)-4,5-diphenyl-1H-imida...)
Show SMILES Cc1cc(C)cc(c1)-n1c(nc(c1-c1ccccc1)-c1ccccc1)-c1cn(nc1C1=CC2C=CC=CC2OC1=O)-c1ccccc1
Show InChI InChI=1S/C41H32N4O2/c1-27-22-28(2)24-33(23-27)45-39(30-16-8-4-9-17-30)37(29-14-6-3-7-15-29)42-40(45)35-26-44(32-19-10-5-11-20-32)43-38(35)34-25-31-18-12-13-21-36(31)47-41(34)46/h3-26,31,36H,1-2H3
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.64E+4n/an/an/an/a6.837



Kinnaird College for Women



Assay Description
For α-glucosidase inhibition assay, α-glucosidase enzyme (Cat No. 5003-1KU Type I; isolated from Saccharomyces cereviciae) was used. Acarbo...


Bioorg Chem 73: 1-9 (2017)


Article DOI: 10.1016/j.bioorg.2017.05.009
BindingDB Entry DOI: 10.7270/Q2TD9W62
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Saccharomyces cerevisiae (Baker's yeast))
BDBM231686
PNG
(3-(4-(4,5-Diphenyl-1-propyl-1H-imidazol-2-yl)-1-ph...)
Show SMILES CCCn1c(nc(c1-c1ccccc1)-c1ccccc1)-c1cn(nc1C1=CC2C=CC=CC2OC1=O)-c1ccccc1
Show InChI InChI=1S/C36H30N4O2/c1-2-22-39-34(26-16-8-4-9-17-26)32(25-14-6-3-7-15-25)37-35(39)30-24-40(28-19-10-5-11-20-28)38-33(30)29-23-27-18-12-13-21-31(27)42-36(29)41/h3-21,23-24,27,31H,2,22H2,1H3
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.48E+4n/an/an/an/a6.837



Kinnaird College for Women



Assay Description
For α-glucosidase inhibition assay, α-glucosidase enzyme (Cat No. 5003-1KU Type I; isolated from Saccharomyces cereviciae) was used. Acarbo...


Bioorg Chem 73: 1-9 (2017)


Article DOI: 10.1016/j.bioorg.2017.05.009
BindingDB Entry DOI: 10.7270/Q2TD9W62
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Saccharomyces cerevisiae (Baker's yeast))
BDBM231687
PNG
(6-Bromo-3-(4-(1-(4-chlorophenyl)-4,5-diphenyl-1H-i...)
Show SMILES Clc1ccc(cc1)-n1c(nc(c1-c1ccccc1)-c1ccccc1)-c1cn(nc1-c1cc2cc(Br)ccc2oc1=O)-c1ccccc1
Show InChI InChI=1S/C39H24BrClN4O2/c40-28-16-21-34-27(22-28)23-32(39(46)47-34)36-33(24-44(43-36)30-14-8-3-9-15-30)38-42-35(25-10-4-1-5-11-25)37(26-12-6-2-7-13-26)45(38)31-19-17-29(41)18-20-31/h1-24H
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.53E+3n/an/an/an/a6.837



Kinnaird College for Women



Assay Description
For α-glucosidase inhibition assay, α-glucosidase enzyme (Cat No. 5003-1KU Type I; isolated from Saccharomyces cereviciae) was used. Acarbo...


Bioorg Chem 73: 1-9 (2017)


Article DOI: 10.1016/j.bioorg.2017.05.009
BindingDB Entry DOI: 10.7270/Q2TD9W62
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Saccharomyces cerevisiae (Baker's yeast))
BDBM231688
PNG
(6-Bromo-3-(4-(1-(3,5-dimethylphenyl)-4,5-diphenyl-...)
Show SMILES Cc1cc(C)cc(c1)-n1c(nc(c1-c1ccccc1)-c1ccccc1)-c1cn(nc1C1=CC2C=C(Br)C=CC2OC1=O)-c1ccccc1
Show InChI InChI=1S/C41H31BrN4O2/c1-26-20-27(2)22-33(21-26)46-39(29-14-8-4-9-15-29)37(28-12-6-3-7-13-28)43-40(46)35-25-45(32-16-10-5-11-17-32)44-38(35)34-24-30-23-31(42)18-19-36(30)48-41(34)47/h3-25,30,36H,1-2H3
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.64E+3n/an/an/an/a6.837



Kinnaird College for Women



Assay Description
For α-glucosidase inhibition assay, α-glucosidase enzyme (Cat No. 5003-1KU Type I; isolated from Saccharomyces cereviciae) was used. Acarbo...


Bioorg Chem 73: 1-9 (2017)


Article DOI: 10.1016/j.bioorg.2017.05.009
BindingDB Entry DOI: 10.7270/Q2TD9W62
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Saccharomyces cerevisiae (Baker's yeast))
BDBM231689
PNG
(6-Bromo-3-(4-(1-(4-methoxyphenyl)-4,5-diphenyl-1Hi...)
Show SMILES COc1ccc(cc1)-n1c(nc(c1-c1ccccc1)-c1ccccc1)-c1cn(nc1-c1cc2cc(Br)ccc2oc1=O)-c1ccccc1
Show InChI InChI=1S/C40H27BrN4O3/c1-47-32-20-18-31(19-21-32)45-38(27-13-7-3-8-14-27)36(26-11-5-2-6-12-26)42-39(45)34-25-44(30-15-9-4-10-16-30)43-37(34)33-24-28-23-29(41)17-22-35(28)48-40(33)46/h2-25H,1H3
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.27E+3n/an/an/an/a6.837



Kinnaird College for Women



Assay Description
For α-glucosidase inhibition assay, α-glucosidase enzyme (Cat No. 5003-1KU Type I; isolated from Saccharomyces cereviciae) was used. Acarbo...


Bioorg Chem 73: 1-9 (2017)


Article DOI: 10.1016/j.bioorg.2017.05.009
BindingDB Entry DOI: 10.7270/Q2TD9W62
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Saccharomyces cerevisiae (Baker's yeast))
BDBM231690
PNG
(6-Bromo-3-(4-(4,5-diphenyl-1-(p-tolyl)-1H-imidazol...)
Show SMILES Cc1ccc(cc1)-n1c(nc(c1-c1ccccc1)-c1ccccc1)-c1cn(nc1-c1cc2cc(Br)ccc2oc1=O)-c1ccccc1
Show InChI InChI=1S/C40H27BrN4O2/c1-26-17-20-32(21-18-26)45-38(28-13-7-3-8-14-28)36(27-11-5-2-6-12-27)42-39(45)34-25-44(31-15-9-4-10-16-31)43-37(34)33-24-29-23-30(41)19-22-35(29)47-40(33)46/h2-25H,1H3
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.83E+3n/an/an/an/a6.837



Kinnaird College for Women



Assay Description
For α-glucosidase inhibition assay, α-glucosidase enzyme (Cat No. 5003-1KU Type I; isolated from Saccharomyces cereviciae) was used. Acarbo...


Bioorg Chem 73: 1-9 (2017)


Article DOI: 10.1016/j.bioorg.2017.05.009
BindingDB Entry DOI: 10.7270/Q2TD9W62
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Saccharomyces cerevisiae (Baker's yeast))
BDBM231691
PNG
(6-Bromo-3-(4-(1-(4-bromophenyl)-4,5-diphenyl-1H-im...)
Show SMILES Brc1ccc(cc1)-n1c(nc(c1-c1ccccc1)-c1ccccc1)-c1cn(nc1-c1cc2cc(Br)ccc2oc1=O)-c1ccccc1
Show InChI InChI=1S/C39H24Br2N4O2/c40-28-16-19-31(20-17-28)45-37(26-12-6-2-7-13-26)35(25-10-4-1-5-11-25)42-38(45)33-24-44(30-14-8-3-9-15-30)43-36(33)32-23-27-22-29(41)18-21-34(27)47-39(32)46/h1-24H
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.21E+3n/an/an/an/a6.837



Kinnaird College for Women



Assay Description
For α-glucosidase inhibition assay, α-glucosidase enzyme (Cat No. 5003-1KU Type I; isolated from Saccharomyces cereviciae) was used. Acarbo...


Bioorg Chem 73: 1-9 (2017)


Article DOI: 10.1016/j.bioorg.2017.05.009
BindingDB Entry DOI: 10.7270/Q2TD9W62
More data for this
Ligand-Target Pair
alpha-Glucosidase (α-Glucosidase)


(Saccharomyces cerevisiae (Baker's yeast))
BDBM23406
PNG
((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Show SMILES C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)OC(O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23?,24-,25-/m1/s1
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 3.83E+4n/an/an/an/a6.837



Kinnaird College for Women



Assay Description
For α-glucosidase inhibition assay, α-glucosidase enzyme (Cat No. 5003-1KU Type I; isolated from Saccharomyces cereviciae) was used. Acarbo...


Bioorg Chem 73: 1-9 (2017)


Article DOI: 10.1016/j.bioorg.2017.05.009
BindingDB Entry DOI: 10.7270/Q2TD9W62
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM222066
PNG
(2-(4-(5,6-Dimethyl-1H-benzo[d]imidazol-2-yl)benzoy...)
Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)NNC(=S)Nc1cccc(F)c1
Show InChI InChI=1S/C23H20FN5OS/c1-13-10-19-20(11-14(13)2)27-21(26-19)15-6-8-16(9-7-15)22(30)28-29-23(31)25-18-5-3-4-17(24)12-18/h3-12H,1-2H3,(H,26,27)(H,28,30)(H2,25,29,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.47E+5n/an/an/an/a6.837



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Zawawi et al. [Zawawi et al., Bioorg. Chem., 23:3119] with slight ...


Bioorg Chem 70: 184-191 (2017)


Article DOI: 10.1016/j.bioorg.2016.12.009
BindingDB Entry DOI: 10.7270/Q27P8X71
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM222067
PNG
(2-(4-(5,6-Dimethyl-1H-benzo[d]imidazol-2-yl)benzoy...)
Show SMILES COc1cccc(NC(=S)NNC(=O)c2ccc(cc2)-c2nc3cc(C)c(C)cc3[nH]2)c1
Show InChI InChI=1S/C24H23N5O2S/c1-14-11-20-21(12-15(14)2)27-22(26-20)16-7-9-17(10-8-16)23(30)28-29-24(32)25-18-5-4-6-19(13-18)31-3/h4-13H,1-3H3,(H,26,27)(H,28,30)(H2,25,29,32)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.18E+4n/an/an/an/a6.837



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Zawawi et al. [Zawawi et al., Bioorg. Chem., 23:3119] with slight ...


Bioorg Chem 70: 184-191 (2017)


Article DOI: 10.1016/j.bioorg.2016.12.009
BindingDB Entry DOI: 10.7270/Q27P8X71
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM222068
PNG
(2-(4-(5,6-Dimethyl-1H-benzo[d]imidazol-2-yl)benzoy...)
Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)NNC(=S)Nc1cccc(c1)[N+]([O-])=O
Show InChI InChI=1S/C23H20N6O3S/c1-13-10-19-20(11-14(13)2)26-21(25-19)15-6-8-16(9-7-15)22(30)27-28-23(33)24-17-4-3-5-18(12-17)29(31)32/h3-12H,1-2H3,(H,25,26)(H,27,30)(H2,24,28,33)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.17E+5n/an/an/an/a6.837



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Zawawi et al. [Zawawi et al., Bioorg. Chem., 23:3119] with slight ...


Bioorg Chem 70: 184-191 (2017)


Article DOI: 10.1016/j.bioorg.2016.12.009
BindingDB Entry DOI: 10.7270/Q27P8X71
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM222069
PNG
(N-(4-bromophenyl)-2-(4-(5,6-dimethyl-1H-benzo[d]im...)
Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)NNC(=S)Nc1ccc(Br)cc1
Show InChI InChI=1S/C23H20BrN5OS/c1-13-11-19-20(12-14(13)2)27-21(26-19)15-3-5-16(6-4-15)22(30)28-29-23(31)25-18-9-7-17(24)8-10-18/h3-12H,1-2H3,(H,26,27)(H,28,30)(H2,25,29,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 5.06E+4n/an/an/an/a6.837



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Zawawi et al. [Zawawi et al., Bioorg. Chem., 23:3119] with slight ...


Bioorg Chem 70: 184-191 (2017)


Article DOI: 10.1016/j.bioorg.2016.12.009
BindingDB Entry DOI: 10.7270/Q27P8X71
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM222070
PNG
(N-(4-chlorophenyl)-2-(4-(5,6-dimethyl-1H-benzo[d]i...)
Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)NNC(=S)Nc1ccc(Cl)cc1
Show InChI InChI=1S/C23H20ClN5OS/c1-13-11-19-20(12-14(13)2)27-21(26-19)15-3-5-16(6-4-15)22(30)28-29-23(31)25-18-9-7-17(24)8-10-18/h3-12H,1-2H3,(H,26,27)(H,28,30)(H2,25,29,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.87E+5n/an/an/an/a6.837



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Zawawi et al. [Zawawi et al., Bioorg. Chem., 23:3119] with slight ...


Bioorg Chem 70: 184-191 (2017)


Article DOI: 10.1016/j.bioorg.2016.12.009
BindingDB Entry DOI: 10.7270/Q27P8X71
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM222071
PNG
(2-(4-(5,6-Dimethyl-1H-benzo[d]imidazol-2-yl)benzoy...)
Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)NNC(=S)Nc1ccc(F)cc1
Show InChI InChI=1S/C23H20FN5OS/c1-13-11-19-20(12-14(13)2)27-21(26-19)15-3-5-16(6-4-15)22(30)28-29-23(31)25-18-9-7-17(24)8-10-18/h3-12H,1-2H3,(H,26,27)(H,28,30)(H2,25,29,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.77E+5n/an/an/an/a6.837



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Zawawi et al. [Zawawi et al., Bioorg. Chem., 23:3119] with slight ...


Bioorg Chem 70: 184-191 (2017)


Article DOI: 10.1016/j.bioorg.2016.12.009
BindingDB Entry DOI: 10.7270/Q27P8X71
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM222072
PNG
(2-(4-(5,6-Dimethyl-1H-benzo[d]imidazol-2-yl)benzoy...)
Show SMILES COc1ccc(NC(=S)NNC(=O)c2ccc(cc2)-c2nc3cc(C)c(C)cc3[nH]2)cc1
Show InChI InChI=1S/C24H23N5O2S/c1-14-12-20-21(13-15(14)2)27-22(26-20)16-4-6-17(7-5-16)23(30)28-29-24(32)25-18-8-10-19(31-3)11-9-18/h4-13H,1-3H3,(H,26,27)(H,28,30)(H2,25,29,32)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.05E+5n/an/an/an/a6.837



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Zawawi et al. [Zawawi et al., Bioorg. Chem., 23:3119] with slight ...


Bioorg Chem 70: 184-191 (2017)


Article DOI: 10.1016/j.bioorg.2016.12.009
BindingDB Entry DOI: 10.7270/Q27P8X71
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM222073
PNG
(2-(4-(5,6-Dimethyl-1H-benzo[d]imidazol-2-yl)benzoy...)
Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)NNC(=S)Nc1ccc(cc1)[N+]([O-])=O
Show InChI InChI=1S/C23H20N6O3S/c1-13-11-19-20(12-14(13)2)26-21(25-19)15-3-5-16(6-4-15)22(30)27-28-23(33)24-17-7-9-18(10-8-17)29(31)32/h3-12H,1-2H3,(H,25,26)(H,27,30)(H2,24,28,33)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.58E+4n/an/an/an/a6.837



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Zawawi et al. [Zawawi et al., Bioorg. Chem., 23:3119] with slight ...


Bioorg Chem 70: 184-191 (2017)


Article DOI: 10.1016/j.bioorg.2016.12.009
BindingDB Entry DOI: 10.7270/Q27P8X71
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM222074
PNG
(2-(4-(5,6-Dimethyl-1H-benzo[d]imidazol-2-yl)benzoy...)
Show SMILES Cc1cc2nc([nH]c2cc1C)-c1ccc(cc1)C(=O)NNC(=S)Nc1ccc(cc1)C(F)(F)F
Show InChI InChI=1S/C24H20F3N5OS/c1-13-11-19-20(12-14(13)2)30-21(29-19)15-3-5-16(6-4-15)22(33)31-32-23(34)28-18-9-7-17(8-10-18)24(25,26)27/h3-12H,1-2H3,(H,29,30)(H,31,33)(H2,28,32,34)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.63E+5n/an/an/an/a6.837



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Zawawi et al. [Zawawi et al., Bioorg. Chem., 23:3119] with slight ...


Bioorg Chem 70: 184-191 (2017)


Article DOI: 10.1016/j.bioorg.2016.12.009
BindingDB Entry DOI: 10.7270/Q27P8X71
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM222075
PNG
(2-(4-(5,6-Dimethyl-1H-benzo[d]imidazol-2-yl)benzoy...)
Show SMILES Cc1cccc(NC(=S)NNC(=O)c2ccc(cc2)-c2nc3cc(C)c(C)cc3[nH]2)c1
Show InChI InChI=1S/C24H23N5OS/c1-14-5-4-6-19(11-14)25-24(31)29-28-23(30)18-9-7-17(8-10-18)22-26-20-12-15(2)16(3)13-21(20)27-22/h4-13H,1-3H3,(H,26,27)(H,28,30)(H2,25,29,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.19E+5n/an/an/an/a6.837



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Zawawi et al. [Zawawi et al., Bioorg. Chem., 23:3119] with slight ...


Bioorg Chem 70: 184-191 (2017)


Article DOI: 10.1016/j.bioorg.2016.12.009
BindingDB Entry DOI: 10.7270/Q27P8X71
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM222076
PNG
(2-(4-(5,6-Dimethyl-1H-benzo[d]imidazol-2-yl)benzoy...)
Show SMILES Cc1ccc(NC(=S)NNC(=O)c2ccc(cc2)-c2nc3cc(C)c(C)cc3[nH]2)cc1
Show InChI InChI=1S/C24H23N5OS/c1-14-4-10-19(11-5-14)25-24(31)29-28-23(30)18-8-6-17(7-9-18)22-26-20-12-15(2)16(3)13-21(20)27-22/h4-13H,1-3H3,(H,26,27)(H,28,30)(H2,25,29,31)
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.98E+5n/an/an/an/a6.837



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Zawawi et al. [Zawawi et al., Bioorg. Chem., 23:3119] with slight ...


Bioorg Chem 70: 184-191 (2017)


Article DOI: 10.1016/j.bioorg.2016.12.009
BindingDB Entry DOI: 10.7270/Q27P8X71
More data for this
Ligand-Target Pair
α-glucosidase


(Saccharomyces cerevisiae S288c (Baker's yeast))
BDBM23406
PNG
((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Show SMILES C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)OC(O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23?,24-,25-/m1/s1
PDB
MMDB

Reactome pathway
KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 7.75E+5n/an/an/an/a6.837



Universiti Teknologi MARA (UiTM)



Assay Description
The enzyme inhibition was evaluated according to the method previously reported by Zawawi et al. [Zawawi et al., Bioorg. Chem., 23:3119] with slight ...


Bioorg Chem 70: 184-191 (2017)


Article DOI: 10.1016/j.bioorg.2016.12.009
BindingDB Entry DOI: 10.7270/Q27P8X71
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223106
PNG
((Z)-2-((2-oxo-2H-chromen-7-yl)oxy)-N'-(2-oxoin...)
Show SMILES O=C(COc1ccc2ccc(=O)oc2c1)N\N=C1/C(=O)Nc2ccccc12
Show InChI InChI=1S/C19H13N3O5/c23-16(21-22-18-13-3-1-2-4-14(13)20-19(18)25)10-26-12-7-5-11-6-8-17(24)27-15(11)9-12/h1-9H,10H2,(H,21,23)(H,20,22,25)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.87E+5n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223107
PNG
((Z)-N'-(5-methyl-2-oxoindolin-3-ylidene)-2-((2...)
Show SMILES Cc1ccc2NC(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c2c1
Show InChI InChI=1S/C20H15N3O5/c1-11-2-6-15-14(8-11)19(20(26)21-15)23-22-17(24)10-27-13-5-3-12-4-7-18(25)28-16(12)9-13/h2-9H,10H2,1H3,(H,22,24)(H,21,23,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.14E+5n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223108
PNG
((Z)-N'-(5,7-dimethyl-2-oxoindolin-3-ylidene)-2...)
Show SMILES Cc1cc2\C(=N\NC(=O)COc3ccc4ccc(=O)oc4c3)C(=O)Nc2c(C)c1
Show InChI InChI=1S/C21H17N3O5/c1-11-7-12(2)19-15(8-11)20(21(27)22-19)24-23-17(25)10-28-14-5-3-13-4-6-18(26)29-16(13)9-14/h3-9H,10H2,1-2H3,(H,23,25)(H,22,24,27)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.97E+5n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223109
PNG
((Z)-N'-(5-fluoro-2-oxoindolin-3-ylidene)-2-((2...)
Show SMILES Fc1ccc2NC(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c2c1
Show InChI InChI=1S/C19H12FN3O5/c20-11-3-5-14-13(7-11)18(19(26)21-14)23-22-16(24)9-27-12-4-1-10-2-6-17(25)28-15(10)8-12/h1-8H,9H2,(H,22,24)(H,21,23,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.20E+4n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223110
PNG
((Z)-N'-(5-chloro-2-oxoindolin-3-ylidene)-2-((2...)
Show SMILES Clc1ccc2NC(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c2c1
Show InChI InChI=1S/C19H12ClN3O5/c20-11-3-5-14-13(7-11)18(19(26)21-14)23-22-16(24)9-27-12-4-1-10-2-6-17(25)28-15(10)8-12/h1-8H,9H2,(H,22,24)(H,21,23,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.53E+5n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223111
PNG
((Z)-N'-(5-bromo-2-oxoindolin-3-ylidene)-2-((2-...)
Show SMILES Brc1ccc2NC(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c2c1
Show InChI InChI=1S/C19H12BrN3O5/c20-11-3-5-14-13(7-11)18(19(26)21-14)23-22-16(24)9-27-12-4-1-10-2-6-17(25)28-15(10)8-12/h1-8H,9H2,(H,22,24)(H,21,23,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.42E+4n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223112
PNG
((Z)-N'-(5-nitro-2-oxoindolin-3-ylidene)-2-((2-...)
Show SMILES [O-][N+](=O)c1ccc2NC(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c2c1
Show InChI InChI=1S/C19H12N4O7/c24-16(9-29-12-4-1-10-2-6-17(25)30-15(10)8-12)21-22-18-13-7-11(23(27)28)3-5-14(13)20-19(18)26/h1-8H,9H2,(H,21,24)(H,20,22,26)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.47E+3n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223113
PNG
((Z)-N'-(1-methyl-2-oxoindolin-3-ylidene)-2-((2...)
Show SMILES CN1C(=O)\C(=N/NC(=O)COc2ccc3ccc(=O)oc3c2)c2ccccc12
Show InChI InChI=1S/C20H15N3O5/c1-23-15-5-3-2-4-14(15)19(20(23)26)22-21-17(24)11-27-13-8-6-12-7-9-18(25)28-16(12)10-13/h2-10H,11H2,1H3,(H,21,24)/b22-19-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.69E+5n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223114
PNG
((Z)-N'-(1-benzyl-2-oxoindolin-3-ylidene)-2-((2...)
Show SMILES O=C(COc1ccc2ccc(=O)oc2c1)N\N=C1/C(=O)N(Cc2ccccc2)c2ccccc12
Show InChI InChI=1S/C26H19N3O5/c30-23(16-33-19-12-10-18-11-13-24(31)34-22(18)14-19)27-28-25-20-8-4-5-9-21(20)29(26(25)32)15-17-6-2-1-3-7-17/h1-14H,15-16H2,(H,27,30)/b28-25-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 1.41E+4n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223115
PNG
((Z)-N'-(1-(2-fluorobenzyl)-2-oxoindolin-3-ylid...)
Show SMILES Fc1ccccc1CN1C(=O)\C(=N/NC(=O)COc2ccc3ccc(=O)oc3c2)c2ccccc12
Show InChI InChI=1S/C26H18FN3O5/c27-20-7-3-1-5-17(20)14-30-21-8-4-2-6-19(21)25(26(30)33)29-28-23(31)15-34-18-11-9-16-10-12-24(32)35-22(16)13-18/h1-13H,14-15H2,(H,28,31)/b29-25-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.37E+3n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223116
PNG
((Z)-N'-(1-(3-fluorobenzyl)-2-oxoindolin-3-ylid...)
Show SMILES Fc1cccc(CN2C(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c3ccccc23)c1
Show InChI InChI=1S/C26H18FN3O5/c27-18-5-3-4-16(12-18)14-30-21-7-2-1-6-20(21)25(26(30)33)29-28-23(31)15-34-19-10-8-17-9-11-24(32)35-22(17)13-19/h1-13H,14-15H2,(H,28,31)/b29-25-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 9.33E+3n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223117
PNG
((Z)-N'-(1-(2-chlorobenzyl)-2-oxoindolin-3-ylid...)
Show SMILES Clc1ccccc1CN1C(=O)\C(=N/NC(=O)COc2ccc3ccc(=O)oc3c2)c2ccccc12
Show InChI InChI=1S/C26H18ClN3O5/c27-20-7-3-1-5-17(20)14-30-21-8-4-2-6-19(21)25(26(30)33)29-28-23(31)15-34-18-11-9-16-10-12-24(32)35-22(16)13-18/h1-13H,14-15H2,(H,28,31)/b29-25-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.31E+3n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223118
PNG
((Z)-N'-(1-(4-bromobenzyl)-2-oxoindolin-3-ylide...)
Show SMILES Brc1ccc(CN2C(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c3ccccc23)cc1
Show InChI InChI=1S/C26H18BrN3O5/c27-18-9-5-16(6-10-18)14-30-21-4-2-1-3-20(21)25(26(30)33)29-28-23(31)15-34-19-11-7-17-8-12-24(32)35-22(17)13-19/h1-13H,14-15H2,(H,28,31)/b29-25-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.07E+3n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223119
PNG
((Z)-N'-(1-(2-fluorobenzyl)-5-methyl-2-oxoindol...)
Show SMILES Cc1ccc2N(Cc3ccccc3F)C(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c2c1
Show InChI InChI=1S/C27H20FN3O5/c1-16-6-10-22-20(12-16)26(27(34)31(22)14-18-4-2-3-5-21(18)28)30-29-24(32)15-35-19-9-7-17-8-11-25(33)36-23(17)13-19/h2-13H,14-15H2,1H3,(H,29,32)/b30-26-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 6.68E+4n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223120
PNG
((Z)-N'-(1-(3-fluorobenzyl)-5-methyl-2-oxoindol...)
Show SMILES Cc1ccc2N(Cc3cccc(F)c3)C(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c2c1
Show InChI InChI=1S/C27H20FN3O5/c1-16-5-9-22-21(11-16)26(27(34)31(22)14-17-3-2-4-19(28)12-17)30-29-24(32)15-35-20-8-6-18-7-10-25(33)36-23(18)13-20/h2-13H,14-15H2,1H3,(H,29,32)/b30-26-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 7.78E+4n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223121
PNG
((Z)-N'-(5-chloro-1-(2-fluorobenzyl)-2-oxoindol...)
Show SMILES Fc1ccccc1CN1C(=O)\C(=N/NC(=O)COc2ccc3ccc(=O)oc3c2)c2cc(Cl)ccc12
Show InChI InChI=1S/C26H17ClFN3O5/c27-17-7-9-21-19(11-17)25(26(34)31(21)13-16-3-1-2-4-20(16)28)30-29-23(32)14-35-18-8-5-15-6-10-24(33)36-22(15)12-18/h1-12H,13-14H2,(H,29,32)/b30-25-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.56E+3n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223122
PNG
((Z)-N'-(5-chloro-1-(3-fluorobenzyl)-2-oxoindol...)
Show SMILES Fc1cccc(CN2C(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c3cc(Cl)ccc23)c1
Show InChI InChI=1S/C26H17ClFN3O5/c27-17-6-8-21-20(11-17)25(26(34)31(21)13-15-2-1-3-18(28)10-15)30-29-23(32)14-35-19-7-4-16-5-9-24(33)36-22(16)12-19/h1-12H,13-14H2,(H,29,32)/b30-25-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.88E+3n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223123
PNG
((Z)-N'-(1-benzyl-5-bromo-2-oxoindolin-3-yliden...)
Show SMILES Brc1ccc2N(Cc3ccccc3)C(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c2c1
Show InChI InChI=1S/C26H18BrN3O5/c27-18-8-10-21-20(12-18)25(26(33)30(21)14-16-4-2-1-3-5-16)29-28-23(31)15-34-19-9-6-17-7-11-24(32)35-22(17)13-19/h1-13H,14-15H2,(H,28,31)/b29-25-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 4.48E+3n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223124
PNG
((Z)-N'-(5-bromo-1-(2-chlorobenzyl)-2-oxoindoli...)
Show SMILES Clc1ccccc1CN1C(=O)\C(=N/NC(=O)COc2ccc3ccc(=O)oc3c2)c2cc(Br)ccc12
Show InChI InChI=1S/C26H17BrClN3O5/c27-17-7-9-21-19(11-17)25(26(34)31(21)13-16-3-1-2-4-20(16)28)30-29-23(32)14-35-18-8-5-15-6-10-24(33)36-22(15)12-18/h1-12H,13-14H2,(H,29,32)/b30-25-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 2.85E+3n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM223125
PNG
((Z)-N'-(5-bromo-1-(4-bromobenzyl)-2-oxoindolin...)
Show SMILES Brc1ccc(CN2C(=O)\C(=N/NC(=O)COc3ccc4ccc(=O)oc4c3)c3cc(Br)ccc23)cc1
Show InChI InChI=1S/C26H17Br2N3O5/c27-17-5-1-15(2-6-17)13-31-21-9-7-18(28)11-20(21)25(26(31)34)30-29-23(32)14-35-19-8-3-16-4-10-24(33)36-22(16)12-19/h1-12H,13-14H2,(H,29,32)/b30-25-
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
Article
PubMed
n/an/a 3.98E+3n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM23406
PNG
((3R,4R,5S,6R)-5-{[(2R,3R,4R,5S,6R)-5-{[(2R,3R,4S,5...)
Show SMILES C[C@H]1O[C@H](O[C@@H]2[C@@H](CO)O[C@H](O[C@@H]3[C@@H](CO)OC(O)[C@H](O)[C@H]3O)[C@H](O)[C@H]2O)[C@H](O)[C@@H](O)[C@@H]1N[C@H]1C=C(CO)[C@@H](O)[C@H](O)[C@H]1O
Show InChI InChI=1S/C25H43NO18/c1-6-11(26-8-2-7(3-27)12(30)15(33)13(8)31)14(32)19(37)24(40-6)43-22-10(5-29)42-25(20(38)17(22)35)44-21-9(4-28)41-23(39)18(36)16(21)34/h2,6,8-39H,3-5H2,1H3/t6-,8+,9-,10-,11-,12-,13+,14+,15+,16-,17-,18-,19-,20-,21-,22-,23?,24-,25-/m1/s1
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
Purchase

PC cid
PC sid
UniChem

Similars

Article
PubMed
n/an/a 8.17E+5n/an/an/an/a6.8n/a



Jishou University



Assay Description
The test compounds were dissolved in DMSO to prepare the required distributing concentration. α-Glucosidase inhibitory activity was assayed usin...


Chem Biol Drug Des 89: 456-463 (2017)


Article DOI: 10.1111/cbdd.12867
BindingDB Entry DOI: 10.7270/Q25M64KX
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM225281
PNG
(1H,1''H-[3,3':3',3''-terin...)
Show SMILES O=C1Nc2ccccc2C1(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12
Show InChI InChI=1S/C24H17N3O/c28-23-24(17-9-3-6-12-22(17)27-23,18-13-25-20-10-4-1-7-15(18)20)19-14-26-21-11-5-2-8-16(19)21/h1-14,25-26H,(H,27,28)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 1.46E+5n/an/an/an/a6.837



Jishou University



Assay Description
The α-glucosidase inhibition assay had been carried out using baker's yeast α-glucosidase (EC 3.2.1.20) and p-nitrophenyl α-d-gluco...


Bioorg Chem 72: 228-233 (2017)


BindingDB Entry DOI: 10.7270/Q2DV1HSV
More data for this
Ligand-Target Pair
alpha-Glucosidase (alpha-Glu)


(Saccharomyces cerevisiae)
BDBM225282
PNG
(5'-Bromo-1H,1''H-[3,3':3',3...)
Show SMILES Brc1ccc2NC(=O)C(c2c1)(c1c[nH]c2ccccc12)c1c[nH]c2ccccc12
Show InChI InChI=1S/C24H16BrN3O/c25-14-9-10-22-17(11-14)24(23(29)28-22,18-12-26-20-7-3-1-5-15(18)20)19-13-27-21-8-4-2-6-16(19)21/h1-13,26-27H,(H,28,29)
Reactome pathway
KEGG

UniProtKB/SwissProt

GoogleScholar
AffyNet 
PC cid
PC sid
UniChem
n/an/a 2.05E+4n/an/an/an/a6.837



Jishou University



Assay Description
The α-glucosidase inhibition assay had been carried out using baker's yeast α-glucosidase (EC 3.2.1.20) and p-nitrophenyl α-d-gluco...


Bioorg Chem 72: 228-233 (2017)


BindingDB Entry DOI: 10.7270/Q2DV1HSV
More data for this
Ligand-Target Pair
Displayed 1 to 50 (of 549 total )  |  Next  |  Last  >>
Jump to: