TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
University Of North Carolina At Chapel Hill
Affinity DataIC50: 1nMpH: 7.5 T: 2°CAssay Description:PDE4 catalytic activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using PDE-SPA kit (Amersham International). [3H]-AMP was c...More data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
University Of North Carolina At Chapel Hill
Affinity DataIC50: 135nMpH: 7.5 T: 2°CAssay Description:PDE4 catalytic activity was monitored by measuring the hydrolysis of [3H]-cAMP to [3H]-AMP using PDE-SPA kit (Amersham International). [3H]-AMP was c...More data for this Ligand-Target Pair
Affinity DataKi: 0.00230nMAssay Description:Binding affinity towards rolipram binding site on phosphodiesterase 4 using [3H]rolipram as radioligand in crude rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 0.0190nMAssay Description:Binding affinity towards rolipram binding site on phosphodiesterase 4 using [3H]rolipram as radioligand in crude rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 0.0420nMAssay Description:Binding affinity towards rolipram binding site on phosphodiesterase 4 using [3H]rolipram as radioligand in crude rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 0.0460nMAssay Description:Binding affinity towards rolipram binding site on phosphodiesterase 4 using [3H]rolipram as radioligand in crude rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 0.0690nMAssay Description:Binding affinity towards rolipram binding site on phosphodiesterase 4 using [3H]rolipram as radioligand in crude rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 0.0920nMAssay Description:Binding affinity towards rolipram binding site on phosphodiesterase 4 using [3H]rolipram as radioligand in crude rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 0.146nMAssay Description:Binding affinity towards rolipram binding site on phosphodiesterase 4 using [3H]rolipram as radioligand in crude rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 0.336nMAssay Description:Binding affinity towards rolipram binding site on phosphodiesterase 4 using [3H]rolipram as radioligand in crude rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 1.20nMAssay Description:Binding affinity towards rolipram binding site on phosphodiesterase 4 using [3H]rolipram as radioligand in crude rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 1.60nMAssay Description:Binding affinity towards rolipram binding site on phosphodiesterase 4 using [3H]rolipram as radioligand in crude rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 2nMAssay Description:Binding affinity towards rolipram binding site on phosphodiesterase 4 using [3H]rolipram as radioligand in crude rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 2.30nMAssay Description:Binding affinity towards rolipram binding site on phosphodiesterase 4 using [3H]rolipram as radioligand in crude rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 2.70nMAssay Description:Binding affinity towards rolipram binding site on phosphodiesterase 4 using [3H]rolipram as radioligand in crude rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 3.5nMAssay Description:Binding affinity towards rolipram binding site on phosphodiesterase 4 using [3H]rolipram as radioligand in crude rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: >5nMAssay Description:Binding affinity towards rolipram binding site on phosphodiesterase 4 using [3H]rolipram as radioligand in crude rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: >5nMAssay Description:Binding affinity towards rolipram binding site on phosphodiesterase 4 using [3H]rolipram as radioligand in crude rat brain homogenateMore data for this Ligand-Target Pair
Affinity DataKi: 8.00E+3nMAssay Description:Inhibition of rat lung cAMP-phosphodiesteraseMore data for this Ligand-Target Pair
Affinity DataKi: 7.00E+4nMAssay Description:Inhibition of rat lung cAMP-phosphodiesteraseMore data for this Ligand-Target Pair
Affinity DataKi: 5.23E+5nMAssay Description:Inhibition of rat lung cAMP-phosphodiesteraseMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of phosphodiesterase 4 from rat brain cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 14nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 3.20nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.00E+3nMAssay Description:Inhibition of phosphodiesterase 4 from rat brain cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 1.30nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.90E+3nMAssay Description:Inhibition of phosphodiesterase 4 in rat brain cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 2.5nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 40nMAssay Description:Inhibition of phosphodiesterase 4 from rat brain cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 2.60nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 70nMAssay Description:Inhibition of phosphodiesterase 4 from rat brain cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 100nMAssay Description:Inhibition of phosphodiesterase 4 from rat brain cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 180nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 490nMAssay Description:Inhibition of phosphodiesterase 4 from rat brain cortexMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+3nMAssay Description:Displacement of [3H]rolipram binding to Phosphodiesterase 4 in rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: >1.00E+4nMAssay Description:Inhibition of phosphodiesterase 4 from rat brain cortexMore data for this Ligand-Target Pair
Affinity DataIC50: 295nMAssay Description:Inhibition of rolipram binding to rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 621nMAssay Description:Inhibition of rolipram binding to rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of rolipram binding to rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 1.01E+3nMAssay Description:Inhibition of rolipram binding to rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 151nMAssay Description:Inhibition of rolipram binding to rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 350nMAssay Description:Inhibition of rolipram binding to rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 580nMAssay Description:Inhibition of rolipram binding to rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 280nMAssay Description:Inhibition of rolipram binding to rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of rolipram binding to rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 270nMAssay Description:Inhibition of rolipram binding to rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 28nMAssay Description:Inhibition of rolipram binding to rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 84nMAssay Description:Inhibition of rolipram binding to rat brainMore data for this Ligand-Target Pair
Affinity DataIC50: 20nMAssay Description:Inhibition of rolipram binding to rat brainMore data for this Ligand-Target Pair
TargetcAMP-specific 3',5'-cyclic phosphodiesterase 4C(Homo sapiens (Human))
University Of North Carolina At Chapel Hill
University Of North Carolina At Chapel Hill
Affinity DataIC50: 126nMAssay Description:Evaluated in vitro for its inhibitory activity on unpurified recombinant Phosphodiesterase 4CMore data for this Ligand-Target Pair