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Compile Data Set for Download or QSAR

Found 1764 hits Enz. Inhib. hit(s) with Target = 'fMet-Leu-Phe receptor 1/2'   
Target/Host
(Institution)
LigandTarget/Host
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM21692
PNG
(1-(4-chlorophenyl)-3-[1-methyl-3-oxo-2-phenyl-5-(p...)
Show SMILES CC(C)c1c(NC(=O)Nc2ccc(Cl)cc2)c(=O)n(-c2ccccc2)n1C
Show InChI InChI=1S/C20H21ClN4O2/c1-13(2)18-17(23-20(27)22-15-11-9-14(21)10-12-15)19(26)25(24(18)3)16-7-5-4-6-8-16/h4-13H,1-3H3,(H2,22,23,27)
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n/an/an/an/a 44n/an/a7.237



Amgen



Assay Description
hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...


Bioorg Med Chem Lett 17: 6633-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.043
BindingDB Entry DOI: 10.7270/Q25H7DJ4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM21709
PNG
(2-ethyl-1-[(3R)-1-[(5-methoxy-1H-1,3-benzodiazol-2...)
Show SMILES CCc1nc2ccccc2n1[C@@H]1CCN(C1)C(=O)c1nc2ccc(OC)cc2[nH]1
Show InChI InChI=1S/C22H23N5O2/c1-3-20-23-17-6-4-5-7-19(17)27(20)14-10-11-26(13-14)22(28)21-24-16-9-8-15(29-2)12-18(16)25-21/h4-9,12,14H,3,10-11,13H2,1-2H3,(H,24,25)/t14-/m1/s1
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n/an/an/an/a 1.87E+3n/an/a7.237



Amgen



Assay Description
hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...


Bioorg Med Chem Lett 17: 6633-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.043
BindingDB Entry DOI: 10.7270/Q25H7DJ4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM21694
PNG
(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)N1CCC(CC1)n1c2ccccc2[nH]c1=O
Show InChI InChI=1S/C22H22N4O3/c1-29-16-6-7-17-14(12-16)13-19(23-17)21(27)25-10-8-15(9-11-25)26-20-5-3-2-4-18(20)24-22(26)28/h2-7,12-13,15,23H,8-11H2,1H3,(H,24,28)
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n/an/an/an/a 6.39E+3n/an/a7.237



Amgen



Assay Description
hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...


Bioorg Med Chem Lett 17: 6633-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.043
BindingDB Entry DOI: 10.7270/Q25H7DJ4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM21695
PNG
(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)N1CCC(CC1)n1cnc2ccccc12
Show InChI InChI=1S/C22H22N4O2/c1-28-17-6-7-18-15(12-17)13-20(24-18)22(27)25-10-8-16(9-11-25)26-14-23-19-4-2-3-5-21(19)26/h2-7,12-14,16,24H,8-11H2,1H3
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n/an/an/an/a 5.10E+3n/an/a7.237



Amgen



Assay Description
hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...


Bioorg Med Chem Lett 17: 6633-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.043
BindingDB Entry DOI: 10.7270/Q25H7DJ4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM21696
PNG
(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)N1CCC(CC1)n1c(C)nc2ccccc12
Show InChI InChI=1S/C23H24N4O2/c1-15-24-20-5-3-4-6-22(20)27(15)17-9-11-26(12-10-17)23(28)21-14-16-13-18(29-2)7-8-19(16)25-21/h3-8,13-14,17,25H,9-12H2,1-2H3
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n/an/an/an/a 1.02E+3n/an/a7.237



Amgen



Assay Description
hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...


Bioorg Med Chem Lett 17: 6633-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.043
BindingDB Entry DOI: 10.7270/Q25H7DJ4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM21697
PNG
(2-ethyl-1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]pi...)
Show SMILES CCc1nc2ccccc2n1C1CCN(CC1)C(=O)c1cc2cc(OC)ccc2[nH]1
Show InChI InChI=1S/C24H26N4O2/c1-3-23-26-20-6-4-5-7-22(20)28(23)17-10-12-27(13-11-17)24(29)21-15-16-14-18(30-2)8-9-19(16)25-21/h4-9,14-15,17,25H,3,10-13H2,1-2H3
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n/an/an/an/a 690n/an/a7.237



Amgen



Assay Description
hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...


Bioorg Med Chem Lett 17: 6633-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.043
BindingDB Entry DOI: 10.7270/Q25H7DJ4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM21698
PNG
(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)N1CCC(CC1)n1c(CC(C)C)nc2ccccc12
Show InChI InChI=1S/C26H30N4O2/c1-17(2)14-25-28-22-6-4-5-7-24(22)30(25)19-10-12-29(13-11-19)26(31)23-16-18-15-20(32-3)8-9-21(18)27-23/h4-9,15-17,19,27H,10-14H2,1-3H3
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n/an/an/an/a 830n/an/a7.237



Amgen



Assay Description
hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...


Bioorg Med Chem Lett 17: 6633-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.043
BindingDB Entry DOI: 10.7270/Q25H7DJ4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM21699
PNG
(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)N1CCC(CC1)n1c(nc2ccccc12)C(F)(F)F
Show InChI InChI=1S/C23H21F3N4O2/c1-32-16-6-7-17-14(12-16)13-19(27-17)21(31)29-10-8-15(9-11-29)30-20-5-3-2-4-18(20)28-22(30)23(24,25)26/h2-7,12-13,15,27H,8-11H2,1H3
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n/an/an/an/a 1.52E+3n/an/a7.237



Amgen



Assay Description
hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...


Bioorg Med Chem Lett 17: 6633-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.043
BindingDB Entry DOI: 10.7270/Q25H7DJ4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM21700
PNG
(1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]piperidin-...)
Show SMILES COc1ccc2[nH]c(cc2c1)C(=O)N1CCC(CC1)n1c(nc2ccccc12)-c1ccccc1
Show InChI InChI=1S/C28H26N4O2/c1-34-22-11-12-23-20(17-22)18-25(29-23)28(33)31-15-13-21(14-16-31)32-26-10-6-5-9-24(26)30-27(32)19-7-3-2-4-8-19/h2-12,17-18,21,29H,13-16H2,1H3
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n/an/an/an/a 2.71E+3n/an/a7.237



Amgen



Assay Description
hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...


Bioorg Med Chem Lett 17: 6633-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.043
BindingDB Entry DOI: 10.7270/Q25H7DJ4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM21701
PNG
(2-ethyl-1-{1-[(5-methoxy-1H-indol-2-yl)carbonyl]py...)
Show SMILES CCc1nc2ccccc2n1C1CCN(C1)C(=O)c1cc2cc(OC)ccc2[nH]1
Show InChI InChI=1S/C23H24N4O2/c1-3-22-25-19-6-4-5-7-21(19)27(22)16-10-11-26(14-16)23(28)20-13-15-12-17(29-2)8-9-18(15)24-20/h4-9,12-13,16,24H,3,10-11,14H2,1-2H3
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n/an/an/an/a 130n/an/a7.237



Amgen



Assay Description
hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...


Bioorg Med Chem Lett 17: 6633-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.043
BindingDB Entry DOI: 10.7270/Q25H7DJ4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM21702
PNG
(2-ethyl-1-[(3R)-1-[(5-methoxy-1H-indol-2-yl)carbon...)
Show SMILES CCc1nc2ccccc2n1[C@@H]1CCN(C1)C(=O)c1cc2cc(OC)ccc2[nH]1
Show InChI InChI=1S/C23H24N4O2/c1-3-22-25-19-6-4-5-7-21(19)27(22)16-10-11-26(14-16)23(28)20-13-15-12-17(29-2)8-9-18(15)24-20/h4-9,12-13,16,24H,3,10-11,14H2,1-2H3/t16-/m1/s1
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n/an/an/an/a 34n/an/a7.237



Amgen



Assay Description
hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...


Bioorg Med Chem Lett 17: 6633-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.043
BindingDB Entry DOI: 10.7270/Q25H7DJ4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM21703
PNG
(2-ethyl-1-[(3S)-1-[(5-methoxy-1H-indol-2-yl)carbon...)
Show SMILES CCc1nc2ccccc2n1[C@H]1CCN(C1)C(=O)c1cc2cc(OC)ccc2[nH]1
Show InChI InChI=1S/C23H24N4O2/c1-3-22-25-19-6-4-5-7-21(19)27(22)16-10-11-26(14-16)23(28)20-13-15-12-17(29-2)8-9-18(15)24-20/h4-9,12-13,16,24H,3,10-11,14H2,1-2H3/t16-/m0/s1
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n/an/an/an/a 3.50E+3n/an/a7.237



Amgen



Assay Description
hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...


Bioorg Med Chem Lett 17: 6633-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.043
BindingDB Entry DOI: 10.7270/Q25H7DJ4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM21704
PNG
(2-ethyl-1-[(3R)-1-[(5-fluoro-1H-indol-2-yl)carbony...)
Show SMILES CCc1nc2ccccc2n1[C@@H]1CCN(C1)C(=O)c1cc2cc(F)ccc2[nH]1
Show InChI InChI=1S/C22H21FN4O/c1-2-21-25-18-5-3-4-6-20(18)27(21)16-9-10-26(13-16)22(28)19-12-14-11-15(23)7-8-17(14)24-19/h3-8,11-12,16,24H,2,9-10,13H2,1H3/t16-/m1/s1
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n/an/an/an/a 1.49E+3n/an/a7.237



Amgen



Assay Description
hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...


Bioorg Med Chem Lett 17: 6633-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.043
BindingDB Entry DOI: 10.7270/Q25H7DJ4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM21705
PNG
(1-[(3R)-1-[(5-chloro-1H-indol-2-yl)carbonyl]pyrrol...)
Show SMILES CCc1nc2ccccc2n1[C@@H]1CCN(C1)C(=O)c1cc2cc(Cl)ccc2[nH]1
Show InChI InChI=1S/C22H21ClN4O/c1-2-21-25-18-5-3-4-6-20(18)27(21)16-9-10-26(13-16)22(28)19-12-14-11-15(23)7-8-17(14)24-19/h3-8,11-12,16,24H,2,9-10,13H2,1H3/t16-/m1/s1
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n/an/an/an/a 1.41E+4n/an/a7.237



Amgen



Assay Description
hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...


Bioorg Med Chem Lett 17: 6633-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.043
BindingDB Entry DOI: 10.7270/Q25H7DJ4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM21706
PNG
(1-[(3R)-1-[(5-bromo-1H-indol-2-yl)carbonyl]pyrroli...)
Show SMILES CCc1nc2ccccc2n1[C@@H]1CCN(C1)C(=O)c1cc2cc(Br)ccc2[nH]1
Show InChI InChI=1S/C22H21BrN4O/c1-2-21-25-18-5-3-4-6-20(18)27(21)16-9-10-26(13-16)22(28)19-12-14-11-15(23)7-8-17(14)24-19/h3-8,11-12,16,24H,2,9-10,13H2,1H3/t16-/m1/s1
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n/an/an/an/a 810n/an/a7.237



Amgen



Assay Description
hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...


Bioorg Med Chem Lett 17: 6633-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.043
BindingDB Entry DOI: 10.7270/Q25H7DJ4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM21707
PNG
(2-ethyl-1-[(3R)-1-{[5-(trifluoromethoxy)-1H-indol-...)
Show SMILES CCc1nc2ccccc2n1[C@@H]1CCN(C1)C(=O)c1cc2cc(OC(F)(F)F)ccc2[nH]1
Show InChI InChI=1S/C23H21F3N4O2/c1-2-21-28-18-5-3-4-6-20(18)30(21)15-9-10-29(13-15)22(31)19-12-14-11-16(32-23(24,25)26)7-8-17(14)27-19/h3-8,11-12,15,27H,2,9-10,13H2,1H3/t15-/m1/s1
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n/an/an/an/a 1.22E+4n/an/a7.237



Amgen



Assay Description
hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...


Bioorg Med Chem Lett 17: 6633-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.043
BindingDB Entry DOI: 10.7270/Q25H7DJ4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM21708
PNG
(2-ethyl-1-[(3R)-1-[(5-ethyl-1H-indol-2-yl)carbonyl...)
Show SMILES CCc1nc2ccccc2n1[C@@H]1CCN(C1)C(=O)c1cc2cc(CC)ccc2[nH]1
Show InChI InChI=1S/C24H26N4O/c1-3-16-9-10-19-17(13-16)14-21(25-19)24(29)27-12-11-18(15-27)28-22-8-6-5-7-20(22)26-23(28)4-2/h5-10,13-14,18,25H,3-4,11-12,15H2,1-2H3/t18-/m1/s1
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n/an/an/an/a 270n/an/a7.237



Amgen



Assay Description
hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...


Bioorg Med Chem Lett 17: 6633-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.043
BindingDB Entry DOI: 10.7270/Q25H7DJ4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM21693
PNG
(1-(2-chlorophenyl)-3-[1-methyl-3-oxo-2-phenyl-5-(p...)
Show SMILES CC(C)c1c(NC(=O)Nc2ccccc2Cl)c(=O)n(-c2ccccc2)n1C
Show InChI InChI=1S/C20H21ClN4O2/c1-13(2)18-17(23-20(27)22-16-12-8-7-11-15(16)21)19(26)25(24(18)3)14-9-5-4-6-10-14/h4-13H,1-3H3,(H2,22,23,27)
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n/an/an/an/a>1.00E+4n/an/a7.237



Amgen



Assay Description
hFPRL 1 activity was assayed using an aequorin-based bioluminescence assay (Ca2+ flux). EC50 values have been determined by Ca2+ flux in CHO recombin...


Bioorg Med Chem Lett 17: 6633-7 (2007)


Article DOI: 10.1016/j.bmcl.2007.09.043
BindingDB Entry DOI: 10.7270/Q25H7DJ4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM86298
PNG
(WKFMVm-NH2)
Show SMILES CSCC[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(C)C)C(N)=O
Show InChI InChI=1S/C41H61N9O6S2/c1-25(2)35(41(56)46-31(36(44)51)17-20-57-3)50-39(54)33(18-21-58-4)48-40(55)34(22-26-12-6-5-7-13-26)49-38(53)32(16-10-11-19-42)47-37(52)29(43)23-27-24-45-30-15-9-8-14-28(27)30/h5-9,12-15,24-25,29,31-35,45H,10-11,16-23,42-43H2,1-4H3,(H2,44,51)(H,46,56)(H,47,52)(H,48,55)(H,49,53)(H,50,54)/t29-,31+,32+,33-,34-,35-/m0/s1
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18n/an/an/an/an/an/an/an/a



Pohang University of Science and Technology

Curated by PDSP Ki Database




Mol Pharmacol 64: 841-7 (2003)


Article DOI: 10.1124/mol.64.4.841
BindingDB Entry DOI: 10.7270/Q2WQ02D4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM86301
PNG
(WKWMVm-NH2)
Show SMILES CSCC[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1c[nH]c2ccccc12)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(C)C)C(N)=O
Show InChI InChI=1S/C43H62N10O6S2/c1-25(2)37(43(59)49-33(38(46)54)16-19-60-3)53-41(57)35(17-20-61-4)51-42(58)36(22-27-24-48-32-14-8-6-12-29(27)32)52-40(56)34(15-9-10-18-44)50-39(55)30(45)21-26-23-47-31-13-7-5-11-28(26)31/h5-8,11-14,23-25,30,33-37,47-48H,9-10,15-22,44-45H2,1-4H3,(H2,46,54)(H,49,59)(H,50,55)(H,51,58)(H,52,56)(H,53,57)/t30-,33+,34+,35-,36-,37-/m0/s1
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19n/an/an/an/an/an/an/an/a



Pohang University of Science and Technology

Curated by PDSP Ki Database




Mol Pharmacol 64: 841-7 (2003)


Article DOI: 10.1124/mol.64.4.841
BindingDB Entry DOI: 10.7270/Q2WQ02D4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM86299
PNG
(WHYMVm-NH2)
Show SMILES CSCC[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](Cc1cnc[nH]1)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(C)C)C(N)=O
Show InChI InChI=1S/C41H56N10O7S2/c1-23(2)35(41(58)47-31(36(43)53)13-15-59-3)51-38(55)32(14-16-60-4)48-39(56)33(17-24-9-11-27(52)12-10-24)50-40(57)34(19-26-21-44-22-46-26)49-37(54)29(42)18-25-20-45-30-8-6-5-7-28(25)30/h5-12,20-23,29,31-35,45,52H,13-19,42H2,1-4H3,(H2,43,53)(H,44,46)(H,47,58)(H,48,56)(H,49,54)(H,50,57)(H,51,55)/t29-,31+,32-,33-,34+,35-/m0/s1
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32n/an/an/an/an/an/an/an/a



Pohang University of Science and Technology

Curated by PDSP Ki Database




Mol Pharmacol 64: 841-7 (2003)


Article DOI: 10.1124/mol.64.4.841
BindingDB Entry DOI: 10.7270/Q2WQ02D4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM50050937
PNG
((S)-2-[(S)-2-((S)-2-Formylamino-4-methylsulfanyl-b...)
Show SMILES CSCC[C@H](NC=O)C(=O)N[C@@H](CC(C)C)C(=O)N[C@@H](Cc1ccccc1)C(O)=O
Show InChI InChI=1S/C21H31N3O5S/c1-14(2)11-17(23-19(26)16(22-13-25)9-10-30-3)20(27)24-18(21(28)29)12-15-7-5-4-6-8-15/h4-8,13-14,16-18H,9-12H2,1-3H3,(H,22,25)(H,23,26)(H,24,27)(H,28,29)/t16-,17-,18-/m0/s1
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42n/an/an/an/an/an/an/an/a



Universit£ di Genova

Curated by ChEMBL


Assay Description
Displacement of [3H]-fMLP from FPR in human neutrophils


Bioorg Med Chem Lett 17: 3696-701 (2007)


Article DOI: 10.1016/j.bmcl.2007.04.036
BindingDB Entry DOI: 10.7270/Q2R21261
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM86297
PNG
(WKYMVm-NH2)
Show SMILES CSCC[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(C)C)C(N)=O
Show InChI InChI=1S/C41H61N9O7S2/c1-24(2)35(41(57)46-31(36(44)52)16-19-58-3)50-39(55)33(17-20-59-4)48-40(56)34(21-25-12-14-27(51)15-13-25)49-38(54)32(11-7-8-18-42)47-37(53)29(43)22-26-23-45-30-10-6-5-9-28(26)30/h5-6,9-10,12-15,23-24,29,31-35,45,51H,7-8,11,16-22,42-43H2,1-4H3,(H2,44,52)(H,46,57)(H,47,53)(H,48,56)(H,49,54)(H,50,55)/t29-,31+,32+,33-,34-,35-/m0/s1
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47n/an/an/an/an/an/an/an/a



Pohang University of Science and Technology

Curated by PDSP Ki Database




Mol Pharmacol 64: 841-7 (2003)


Article DOI: 10.1124/mol.64.4.841
BindingDB Entry DOI: 10.7270/Q2WQ02D4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM86308
PNG
(WRYMVm-NH2)
Show SMILES CSCC[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCN=C(N)N)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(C)C)C(N)=O
Show InChI InChI=1S/C41H61N11O7S2/c1-23(2)34(40(59)48-30(35(43)54)15-18-60-3)52-38(57)32(16-19-61-4)50-39(58)33(20-24-11-13-26(53)14-12-24)51-37(56)31(10-7-17-46-41(44)45)49-36(55)28(42)21-25-22-47-29-9-6-5-8-27(25)29/h5-6,8-9,11-14,22-23,28,30-34,47,53H,7,10,15-21,42H2,1-4H3,(H2,43,54)(H,48,59)(H,49,55)(H,50,58)(H,51,56)(H,52,57)(H4,44,45,46)/t28-,30+,31+,32-,33-,34-/m0/s1
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55n/an/an/an/an/an/an/an/a



Pohang University of Science and Technology

Curated by PDSP Ki Database




Mol Pharmacol 64: 841-7 (2003)


Article DOI: 10.1124/mol.64.4.841
BindingDB Entry DOI: 10.7270/Q2WQ02D4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM86300
PNG
(WKYM(F/W)m-NH2)
Show SMILES CSCC[C@@H](NC(=O)[C@H](Cc1ccccc1)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C45H61N9O7S2/c1-62-22-19-35(40(48)56)50-44(60)38(24-28-10-4-3-5-11-28)54-43(59)37(20-23-63-2)52-45(61)39(25-29-15-17-31(55)18-16-29)53-42(58)36(14-8-9-21-46)51-41(57)33(47)26-30-27-49-34-13-7-6-12-32(30)34/h3-7,10-13,15-18,27,33,35-39,49,55H,8-9,14,19-26,46-47H2,1-2H3,(H2,48,56)(H,50,60)(H,51,57)(H,52,61)(H,53,58)(H,54,59)/t33-,35+,36+,37-,38-,39-/m0/s1
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57n/an/an/an/an/an/an/an/a



Pohang University of Science and Technology

Curated by PDSP Ki Database




Mol Pharmacol 64: 841-7 (2003)


Article DOI: 10.1124/mol.64.4.841
BindingDB Entry DOI: 10.7270/Q2WQ02D4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM86302
PNG
(WDYMVm-NH2)
Show SMILES CSCC[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CC(O)=O)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(C)C)C(N)=O
Show InChI InChI=1S/C39H54N8O9S2/c1-21(2)33(39(56)43-28(34(41)51)13-15-57-3)47-36(53)29(14-16-58-4)44-37(54)30(17-22-9-11-24(48)12-10-22)46-38(55)31(19-32(49)50)45-35(52)26(40)18-23-20-42-27-8-6-5-7-25(23)27/h5-12,20-21,26,28-31,33,42,48H,13-19,40H2,1-4H3,(H2,41,51)(H,43,56)(H,44,54)(H,45,52)(H,46,55)(H,47,53)(H,49,50)/t26-,28+,29-,30-,31+,33-/m0/s1
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99n/an/an/an/an/an/an/an/a



Pohang University of Science and Technology

Curated by PDSP Ki Database




Mol Pharmacol 64: 841-7 (2003)


Article DOI: 10.1124/mol.64.4.841
BindingDB Entry DOI: 10.7270/Q2WQ02D4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM86303
PNG
(WKHMVm-NH2)
Show SMILES CSCC[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1cnc[nH]1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(C)C)C(N)=O
Show InChI InChI=1S/C38H59N11O6S2/c1-22(2)32(38(55)45-28(33(41)50)12-15-56-3)49-36(53)30(13-16-57-4)47-37(54)31(18-24-20-42-21-44-24)48-35(52)29(11-7-8-14-39)46-34(51)26(40)17-23-19-43-27-10-6-5-9-25(23)27/h5-6,9-10,19-22,26,28-32,43H,7-8,11-18,39-40H2,1-4H3,(H2,41,50)(H,42,44)(H,45,55)(H,46,51)(H,47,54)(H,48,52)(H,49,53)/t26-,28+,29+,30-,31-,32-/m0/s1
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282n/an/an/an/an/an/an/an/a



Pohang University of Science and Technology

Curated by PDSP Ki Database




Mol Pharmacol 64: 841-7 (2003)


Article DOI: 10.1124/mol.64.4.841
BindingDB Entry DOI: 10.7270/Q2WQ02D4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM40404
PNG
(UNM000003536701 | [6-ethyl-2-methyl-3-(1-methylben...)
Show SMILES CCc1cc2c(cc1OC(C)=O)oc(C)c(-c1nc3ccccc3n1C)c2=O
Show InChI InChI=1S/C22H20N2O4/c1-5-14-10-15-19(11-18(14)28-13(3)25)27-12(2)20(21(15)26)22-23-16-8-6-7-9-17(16)24(22)4/h6-11H,5H2,1-4H3
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300n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2Z31X1B
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM86306
PNG
(WEYMVm-NH2)
Show SMILES CSCC[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCC(O)=O)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(C)C)C(N)=O
Show InChI InChI=1S/C40H56N8O9S2/c1-22(2)34(40(57)44-29(35(42)52)15-17-58-3)48-38(55)31(16-18-59-4)46-39(56)32(19-23-9-11-25(49)12-10-23)47-37(54)30(13-14-33(50)51)45-36(53)27(41)20-24-21-43-28-8-6-5-7-26(24)28/h5-12,21-22,27,29-32,34,43,49H,13-20,41H2,1-4H3,(H2,42,52)(H,44,57)(H,45,53)(H,46,56)(H,47,54)(H,48,55)(H,50,51)/t27-,29+,30+,31-,32-,34-/m0/s1
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323n/an/an/an/an/an/an/an/a



Pohang University of Science and Technology

Curated by PDSP Ki Database




Mol Pharmacol 64: 841-7 (2003)


Article DOI: 10.1124/mol.64.4.841
BindingDB Entry DOI: 10.7270/Q2WQ02D4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM86305
PNG
(YMVm-NH2)
Show SMILES CSCC[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@@H](N)Cc1ccc(O)cc1)C(C)C)C(N)=O
Show InChI InChI=1S/C24H39N5O5S2/c1-14(2)20(24(34)27-18(21(26)31)9-11-35-3)29-23(33)19(10-12-36-4)28-22(32)17(25)13-15-5-7-16(30)8-6-15/h5-8,14,17-20,30H,9-13,25H2,1-4H3,(H2,26,31)(H,27,34)(H,28,32)(H,29,33)/t17-,18+,19-,20-/m0/s1
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567n/an/an/an/an/an/an/an/a



Pohang University of Science and Technology

Curated by PDSP Ki Database




Mol Pharmacol 64: 841-7 (2003)


Article DOI: 10.1124/mol.64.4.841
BindingDB Entry DOI: 10.7270/Q2WQ02D4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM86307
PNG
(WKYMYm-NH2)
Show SMILES CSCC[C@@H](NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@H](CCSC)NC(=O)[C@H](Cc1ccc(O)cc1)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(N)=O
Show InChI InChI=1S/C45H61N9O8S2/c1-63-21-18-35(40(48)57)50-44(61)38(23-27-10-14-30(55)15-11-27)54-43(60)37(19-22-64-2)52-45(62)39(24-28-12-16-31(56)17-13-28)53-42(59)36(9-5-6-20-46)51-41(58)33(47)25-29-26-49-34-8-4-3-7-32(29)34/h3-4,7-8,10-17,26,33,35-39,49,55-56H,5-6,9,18-25,46-47H2,1-2H3,(H2,48,57)(H,50,61)(H,51,58)(H,52,62)(H,53,59)(H,54,60)/t33-,35+,36+,37-,38-,39-/m0/s1
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671n/an/an/an/an/an/an/an/a



Pohang University of Science and Technology

Curated by PDSP Ki Database




Mol Pharmacol 64: 841-7 (2003)


Article DOI: 10.1124/mol.64.4.841
BindingDB Entry DOI: 10.7270/Q2WQ02D4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM40402
PNG
(2-furancarboxylic acid [3-(2-methoxyphenyl)-4-oxo-...)
Show SMILES COc1ccccc1-c1c(oc2cc(OC(=O)c3ccco3)ccc2c1=O)C(F)(F)F
Show InChI InChI=1S/C22H13F3O6/c1-28-15-6-3-2-5-13(15)18-19(26)14-9-8-12(30-21(27)16-7-4-10-29-16)11-17(14)31-20(18)22(23,24)25/h2-11H,1H3
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1.10E+3n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2Z31X1B
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM40416
PNG
(2-thiophenecarboxylic acid [3-(2-chlorophenyl)-4-o...)
Show SMILES FC(F)(F)c1oc2cc(OC(=O)c3cccs3)ccc2c(=O)c1-c1ccccc1Cl
Show InChI InChI=1S/C21H10ClF3O4S/c22-14-5-2-1-4-12(14)17-18(26)13-8-7-11(28-20(27)16-6-3-9-30-16)10-15(13)29-19(17)21(23,24)25/h1-10H
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1.10E+3n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2Z31X1B
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM86304
PNG
(WKDMVm-NH2)
Show SMILES CSCC[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CC(O)=O)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(C)C)C(N)=O
Show InChI InChI=1S/C36H57N9O8S2/c1-20(2)30(36(53)41-25(31(39)48)12-15-54-3)45-34(51)27(13-16-55-4)43-35(52)28(18-29(46)47)44-33(50)26(11-7-8-14-37)42-32(49)23(38)17-21-19-40-24-10-6-5-9-22(21)24/h5-6,9-10,19-20,23,25-28,30,40H,7-8,11-18,37-38H2,1-4H3,(H2,39,48)(H,41,53)(H,42,49)(H,43,52)(H,44,50)(H,45,51)(H,46,47)/t23-,25+,26+,27-,28-,30-/m0/s1
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1.30E+3n/an/an/an/an/an/an/an/a



Pohang University of Science and Technology

Curated by PDSP Ki Database




Mol Pharmacol 64: 841-7 (2003)


Article DOI: 10.1124/mol.64.4.841
BindingDB Entry DOI: 10.7270/Q2WQ02D4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM86296
PNG
(WKEMVm-NH2)
Show SMILES CSCC[C@@H](NC(=O)[C@@H](NC(=O)[C@H](CCSC)NC(=O)[C@H](CCC(O)=O)NC(=O)[C@@H](CCCCN)NC(=O)[C@@H](N)Cc1c[nH]c2ccccc12)C(C)C)C(N)=O
Show InChI InChI=1S/C37H59N9O8S2/c1-21(2)31(37(54)42-26(32(40)49)14-17-55-3)46-36(53)29(15-18-56-4)45-35(52)28(12-13-30(47)48)44-34(51)27(11-7-8-16-38)43-33(50)24(39)19-22-20-41-25-10-6-5-9-23(22)25/h5-6,9-10,20-21,24,26-29,31,41H,7-8,11-19,38-39H2,1-4H3,(H2,40,49)(H,42,54)(H,43,50)(H,44,51)(H,45,52)(H,46,53)(H,47,48)/t24-,26+,27+,28-,29-,31-/m0/s1
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Article
PubMed
1.30E+3n/an/an/an/an/an/an/an/a



Pohang University of Science and Technology

Curated by PDSP Ki Database




Mol Pharmacol 64: 841-7 (2003)


Article DOI: 10.1124/mol.64.4.841
BindingDB Entry DOI: 10.7270/Q2WQ02D4
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM40406
PNG
((4E)-5-(2,5-dimethoxyphenyl)-1-(2-methoxyethyl)-4-...)
Show SMILES COCCN1C(C(C(=O)c2ccccc2)C(=O)C1=O)c1cc(OC)ccc1OC
Show InChI InChI=1S/C22H23NO6/c1-27-12-11-23-19(16-13-15(28-2)9-10-17(16)29-3)18(21(25)22(23)26)20(24)14-7-5-4-6-8-14/h4-10,13,18-19H,11-12H2,1-3H3
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1.80E+3n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2Z31X1B
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM37643
PNG
((4Z)-5-(2,5-dimethoxyphenyl)-1-(2-furanylmethyl)-4...)
Show SMILES COc1ccc(OC)c(c1)C1C(C(=O)c2ccccc2)C(=O)C(=O)N1Cc1ccco1
Show InChI InChI=1S/C24H21NO6/c1-29-16-10-11-19(30-2)18(13-16)21-20(22(26)15-7-4-3-5-8-15)23(27)24(28)25(21)14-17-9-6-12-31-17/h3-13,20-21H,14H2,1-2H3
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2.20E+3n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2NZ862K
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM40750
PNG
(N-(5-imidazo[1,2-a]pyrimidin-2-yl-2-methoxy-phenyl...)
Show SMILES COc1ccc(cc1NC(=O)C(C)C)-c1cn2cccnc2n1
Show InChI InChI=1S/C17H18N4O2/c1-11(2)16(22)19-13-9-12(5-6-15(13)23-3)14-10-21-8-4-7-18-17(21)20-14/h4-11H,1-3H3,(H,19,22)
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2.20E+3n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2SF2TKJ
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM40457
PNG
(3-(4-chlorophenyl)-5-methyl-6-(phenylmethyl)-2-(tr...)
Show SMILES Cc1nc2c(c([nH]n2c(=O)c1Cc1ccccc1)C(F)(F)F)-c1ccc(Cl)cc1
Show InChI InChI=1S/C21H15ClF3N3O/c1-12-16(11-13-5-3-2-4-6-13)20(29)28-19(26-12)17(18(27-28)21(23,24)25)14-7-9-15(22)10-8-14/h2-10,27H,11H2,1H3
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2.50E+3n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2Z31X1B
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM40415
PNG
(2-furancarboxylic acid [3-(2-chlorophenyl)-4-oxo-2...)
Show SMILES FC(F)(F)c1oc2cc(OC(=O)c3ccco3)ccc2c(=O)c1-c1ccccc1Cl
Show InChI InChI=1S/C21H10ClF3O5/c22-14-5-2-1-4-12(14)17-18(26)13-8-7-11(29-20(27)15-6-3-9-28-15)10-16(13)30-19(17)21(23,24)25/h1-10H
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2.50E+3n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2Z31X1B
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM40418
PNG
(2-(2,4-dimethoxyphenyl)-1-(2-morpholin-4-ylethyl)-...)
Show SMILES COc1ccc(C2C(C(=O)c3cccs3)C(=O)C(=O)N2CCN2CCOCC2)c(OC)c1
Show InChI InChI=1S/C23H26N2O6S/c1-29-15-5-6-16(17(14-15)30-2)20-19(21(26)18-4-3-13-32-18)22(27)23(28)25(20)8-7-24-9-11-31-12-10-24/h3-6,13-14,19-20H,7-12H2,1-2H3
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2.90E+3n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2Z31X1B
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM40755
PNG
(2-(4-chlorophenyl)-N-(5-imidazo[1,2-a]pyrimidin-2-...)
Show SMILES COc1ccc(cc1NC(=O)Cc1ccc(Cl)cc1)-c1cn2cccnc2n1
Show InChI InChI=1S/C21H17ClN4O2/c1-28-19-8-5-15(18-13-26-10-2-9-23-21(26)25-18)12-17(19)24-20(27)11-14-3-6-16(22)7-4-14/h2-10,12-13H,11H2,1H3,(H,24,27)
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3.20E+3n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2SF2TKJ
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM37667
PNG
(4-[(E)-[4,5-diketo-1-(2-morpholinoethyl)-2-(2-thie...)
Show SMILES COC(=O)c1[nH]c(C)c(C(=O)C2C(N(CCN3CCOCC3)C(=O)C2=O)c2cccs2)c1C
Show InChI InChI=1S/C23H27N3O6S/c1-13-16(14(2)24-18(13)23(30)31-3)20(27)17-19(15-5-4-12-33-15)26(22(29)21(17)28)7-6-25-8-10-32-11-9-25/h4-5,12,17,19,24H,6-11H2,1-3H3
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3.30E+3n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2NZ862K
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM40413
PNG
(2-furancarboxylic acid [3-(3,4-dimethoxyphenyl)-4-...)
Show SMILES COc1ccc(cc1OC)-c1c(oc2cc(OC(=O)c3ccco3)ccc2c1=O)C(F)(F)F
Show InChI InChI=1S/C23H15F3O7/c1-29-15-8-5-12(10-18(15)30-2)19-20(27)14-7-6-13(32-22(28)16-4-3-9-31-16)11-17(14)33-21(19)23(24,25)26/h3-11H,1-2H3
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3.30E+3n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2Z31X1B
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM40419
PNG
((4E)-5-(2,4-dimethoxyphenyl)-1-(3-imidazol-1-ylpro...)
Show SMILES COc1ccc(C2C(C(=O)c3ccccc3)C(=O)C(=O)N2CCCn2ccnc2)c(OC)c1
Show InChI InChI=1S/C25H25N3O5/c1-32-18-9-10-19(20(15-18)33-2)22-21(23(29)17-7-4-3-5-8-17)24(30)25(31)28(22)13-6-12-27-14-11-26-16-27/h3-5,7-11,14-16,21-22H,6,12-13H2,1-2H3
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3.40E+3n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2Z31X1B
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM50022309
PNG
(3,5-Dioxo-1,2-diphenyl-4-n-butylpyrazolidine | 4-b...)
Show SMILES CCCCc1c(O)n(-c2ccccc2)n(-c2ccccc2)c1=O
Show InChI InChI=1S/C19H20N2O2/c1-2-3-14-17-18(22)20(15-10-6-4-7-11-15)21(19(17)23)16-12-8-5-9-13-16/h4-13,22H,2-3,14H2,1H3
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3.50E+3n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2NZ862K
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens)
BDBM37613
PNG
((4Z)-4-[hydroxy(phenyl)methylene]-1-isobutyl-5-(2-...)
Show SMILES COc1ccccc1C1C(C(=O)c2ccccc2)C(=O)C(=O)N1CC(C)C
Show InChI InChI=1S/C22H23NO4/c1-14(2)13-23-19(16-11-7-8-12-17(16)27-3)18(21(25)22(23)26)20(24)15-9-5-4-6-10-15/h4-12,14,18-19H,13H2,1-3H3
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3.60E+3n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2NZ862K
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM37690
PNG
(MLS000045944 | N-(5-imidazo[1,2-a]pyrimidin-2-yl-2...)
Show SMILES COc1ccc(cc1NC(=O)C1CC1)-c1cn2cccnc2n1
Show InChI InChI=1S/C17H16N4O2/c1-23-15-6-5-12(9-13(15)19-16(22)11-3-4-11)14-10-21-8-2-7-18-17(21)20-14/h2,5-11H,3-4H2,1H3,(H,19,22)
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4.10E+3n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview: Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph...


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2SF2TKJ
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM37792
PNG
(MLS000118373 | SMR000095315 | cid_5308727)
Show SMILES CN1CCN(CC1)c1cc(NCCOC(C)=O)c2C(=O)c3ccccc3-c3onc1c23
Show InChI InChI=1S/C23H24N4O4/c1-14(28)30-12-7-24-17-13-18(27-10-8-26(2)9-11-27)21-20-19(17)22(29)15-5-3-4-6-16(15)23(20)31-25-21/h3-6,13,24H,7-12H2,1-2H3
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4.20E+3n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2DF6PMF
More data for this
Ligand-Target Pair
fMet-Leu-Phe receptor 1/2


(Homo sapiens (human))
BDBM37690
PNG
(MLS000045944 | N-(5-imidazo[1,2-a]pyrimidin-2-yl-2...)
Show SMILES COc1ccc(cc1NC(=O)C1CC1)-c1cn2cccnc2n1
Show InChI InChI=1S/C17H16N4O2/c1-23-15-6-5-12(9-13(15)19-16(22)11-3-4-11)14-10-21-8-2-7-18-17(21)20-14/h2,5-11H,3-4H2,1H3,(H,19,22)
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4.60E+3n/an/an/an/an/an/an/an/a



NMMLSC

Curated by PubChem BioAssay


Assay Description
University of New Mexico Assay Overview Assay Support: NIH 1R03MH076381-01 Assay for Formylpeptide Receptor Family Ligands PI: Bruce S. Edwards, Ph....


PubChem Bioassay (2007)


BindingDB Entry DOI: 10.7270/Q2DF6PMF
More data for this
Ligand-Target Pair
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