Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
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20-alpha-Hydroxysteroid Dehydrogenase (AKR1C1) Mutant (H222S) (Homo sapiens (Human)) | BDBM26269![]() (3,5-dichloro-2-hydroxybenzoic acid | 3,5-dichloros...) | PDB MMDB B.MOAD GoogleScholar | Purchase CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars | PDB Article PubMed | 58 | -41.3 | n/a | n/a | n/a | n/a | n/a | 7.4 | 25 |
Monash University | Assay Description The activity was assayed by measuring the rate of change in NADPH fluorescence (at 455 nm with an excitation wavelength of 340 nm) at 298 K. When the... | J Med Chem 51: 4844-8 (2008) Article DOI: 10.1021/jm8003575 BindingDB Entry DOI: 10.7270/Q2MG7MTW | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |