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Compile Data Set for Download or QSAR

Found 2577 hits Enz. Inhib. hit(s) with Target = '5-lipoxygenase-activating protein (FLAP)' AND taxid = 9606   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM145818
PNG
(US8952177, 174 | US9089569, 174)
Show SMILES Cc1cnc(COc2ccc3nc([C@H]4CCCC[C@H]4C(O)=O)n(Cc4ccc(cc4F)N4CCC(F)CC4)c3c2)c(F)c1
Show InChI InChI=1/C33H35F3N4O3/c1-20-14-28(36)30(37-17-20)19-43-24-8-9-29-31(16-24)40(32(38-29)25-4-2-3-5-26(25)33(41)42)18-21-6-7-23(15-27(21)35)39-12-10-22(34)11-13-39/h6-9,14-17,22,25-26H,2-5,10-13,18-19H2,1H3,(H,41,42)/t25-,26+/s2
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0.340n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9089569 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase-activating protein (FLAP)


(Homo sapiens (Human))
BDBM145818
PNG
(US8952177, 174 | US9089569, 174)
Show SMILES Cc1cnc(COc2ccc3nc([C@H]4CCCC[C@H]4C(O)=O)n(Cc4ccc(cc4F)N4CCC(F)CC4)c3c2)c(F)c1
Show InChI InChI=1/C33H35F3N4O3/c1-20-14-28(36)30(37-17-20)19-43-24-8-9-29-31(16-24)40(32(38-29)25-4-2-3-5-26(25)33(41)42)18-21-6-7-23(15-27(21)35)39-12-10-22(34)11-13-39/h6-9,14-17,22,25-26H,2-5,10-13,18-19H2,1H3,(H,41,42)/t25-,26+/s2
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0.340n/an/an/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
FLAP-containing membranes were prepared as was a FITC-labeled FLAP modulator (3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-in...


US Patent US8952177 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM167060
PNG
(US9073876, 146)
Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(Oc2cc(N)nc(Cc3ccccc3)n2)c1F
Show InChI InChI=1S/C25H23FN6O/c26-24-18(19-13-30-21(28)14-29-19)10-9-17(16-7-4-8-16)25(24)33-23-12-20(27)31-22(32-23)11-15-5-2-1-3-6-15/h1-3,5-6,9-10,12-14,16H,4,7-8,11H2,(H2,28,30)(H2,27,31,32)
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0.400n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9073876 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM169403
PNG
(US9079866, 808)
Show SMILES Nc1cnc(cn1)-c1ccc(cc1F)-c1cccnc1S(=O)(=O)C1CCCCC1
Show InChI InChI=1S/C21H21FN4O2S/c22-18-11-14(8-9-17(18)19-12-26-20(23)13-25-19)16-7-4-10-24-21(16)29(27,28)15-5-2-1-3-6-15/h4,7-13,15H,1-3,5-6H2,(H2,23,26)
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0.400n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM145820
PNG
(US8952177, 176 | US9089569, 176)
Show SMILES Cc1cnc(COc2ccc3nc([C@H]4CCCC[C@H]4C(O)=O)n(Cc4ccc(cc4)N4CCC(F)CC4)c3c2)c(F)c1
Show InChI InChI=1/C33H36F2N4O3/c1-21-16-28(35)30(36-18-21)20-42-25-10-11-29-31(17-25)39(32(37-29)26-4-2-3-5-27(26)33(40)41)19-22-6-8-24(9-7-22)38-14-12-23(34)13-15-38/h6-11,16-18,23,26-27H,2-5,12-15,19-20H2,1H3,(H,40,41)/t26-,27+/s2
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0.420n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9089569 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase-activating protein (FLAP)


(Homo sapiens (Human))
BDBM145820
PNG
(US8952177, 176 | US9089569, 176)
Show SMILES Cc1cnc(COc2ccc3nc([C@H]4CCCC[C@H]4C(O)=O)n(Cc4ccc(cc4)N4CCC(F)CC4)c3c2)c(F)c1
Show InChI InChI=1/C33H36F2N4O3/c1-21-16-28(35)30(36-18-21)20-42-25-10-11-29-31(17-25)39(32(37-29)26-4-2-3-5-27(26)33(40)41)19-22-6-8-24(9-7-22)38-14-12-23(34)13-15-38/h6-11,16-18,23,26-27H,2-5,12-15,19-20H2,1H3,(H,40,41)/t26-,27+/s2
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0.420n/an/an/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
FLAP-containing membranes were prepared as was a FITC-labeled FLAP modulator (3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-in...


US Patent US8952177 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase-activating protein (FLAP)


(Homo sapiens (Human))
BDBM145785
PNG
(US8952177, 139 | US9089569, 139)
Show SMILES Cc1cnc(COc2ccc3nc([C@H]4CCCC[C@H]4C(O)=O)n(Cc4ccc(cc4)-c4ccc(cc4)C(F)(F)F)c3c2)c(F)c1
Show InChI InChI=1/C35H31F4N3O3/c1-21-16-29(36)31(40-18-21)20-45-26-14-15-30-32(17-26)42(33(41-30)27-4-2-3-5-28(27)34(43)44)19-22-6-8-23(9-7-22)24-10-12-25(13-11-24)35(37,38)39/h6-18,27-28H,2-5,19-20H2,1H3,(H,43,44)/t27-,28+/s2
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0.470n/an/an/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
FLAP-containing membranes were prepared as was a FITC-labeled FLAP modulator (3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-in...


US Patent US8952177 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM145785
PNG
(US8952177, 139 | US9089569, 139)
Show SMILES Cc1cnc(COc2ccc3nc([C@H]4CCCC[C@H]4C(O)=O)n(Cc4ccc(cc4)-c4ccc(cc4)C(F)(F)F)c3c2)c(F)c1
Show InChI InChI=1/C35H31F4N3O3/c1-21-16-29(36)31(40-18-21)20-45-26-14-15-30-32(17-26)42(33(41-30)27-4-2-3-5-28(27)34(43)44)19-22-6-8-23(9-7-22)24-10-12-25(13-11-24)35(37,38)39/h6-18,27-28H,2-5,19-20H2,1H3,(H,43,44)/t27-,28+/s2
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0.470n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9089569 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM167191
PNG
(US9073876, 272)
Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(Oc2nc(N)c3ccccc3n2)c1F
Show InChI InChI=1S/C22H19FN6O/c23-19-14(17-10-27-18(24)11-26-17)9-8-13(12-4-3-5-12)20(19)30-22-28-16-7-2-1-6-15(16)21(25)29-22/h1-2,6-12H,3-5H2,(H2,24,27)(H2,25,28,29)
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0.5n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9073876 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM145770
PNG
(US8952177, 124 | US9089569, 124)
Show SMILES Cc1cnc(COc2ccc3nc([C@H]4CCCC[C@@H]4C(O)=O)n(Cc4c(F)cc(Br)cc4F)c3c2)c(F)c1
Show InChI InChI=1/C28H25BrF3N3O3/c1-15-8-23(32)25(33-12-15)14-38-17-6-7-24-26(11-17)35(13-20-21(30)9-16(29)10-22(20)31)27(34-24)18-4-2-3-5-19(18)28(36)37/h6-12,18-19H,2-5,13-14H2,1H3,(H,36,37)/t18-,19-/s2
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0.520n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9089569 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase-activating protein (FLAP)


(Homo sapiens (Human))
BDBM145770
PNG
(US8952177, 124 | US9089569, 124)
Show SMILES Cc1cnc(COc2ccc3nc([C@H]4CCCC[C@@H]4C(O)=O)n(Cc4c(F)cc(Br)cc4F)c3c2)c(F)c1
Show InChI InChI=1/C28H25BrF3N3O3/c1-15-8-23(32)25(33-12-15)14-38-17-6-7-24-26(11-17)35(13-20-21(30)9-16(29)10-22(20)31)27(34-24)18-4-2-3-5-19(18)28(36)37/h6-12,18-19H,2-5,13-14H2,1H3,(H,36,37)/t18-,19-/s2
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0.520n/an/an/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
FLAP-containing membranes were prepared as was a FITC-labeled FLAP modulator (3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-in...


US Patent US8952177 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM169405
PNG
(US9079866, 810)
Show SMILES Nc1cnc(cn1)-c1ccc(cc1F)-c1cccnc1S(=O)(=O)C1CCCC1
Show InChI InChI=1S/C20H19FN4O2S/c21-17-10-13(7-8-16(17)18-11-25-19(22)12-24-18)15-6-3-9-23-20(15)28(26,27)14-4-1-2-5-14/h3,6-12,14H,1-2,4-5H2,(H2,22,25)
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0.600n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM169201
PNG
(US9079866, 602)
Show SMILES Nc1cnc(cn1)-c1ccc(cc1F)-c1ccccc1-c1ccc(c(F)c1)-c1cnc(N)cn1
Show InChI InChI=1S/C26H18F2N6/c27-21-9-15(5-7-19(21)23-11-33-25(29)13-31-23)17-3-1-2-4-18(17)16-6-8-20(22(28)10-16)24-12-34-26(30)14-32-24/h1-14H,(H2,29,33)(H2,30,34)
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0.600n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase-activating protein (FLAP)


(Homo sapiens (Human))
BDBM145769
PNG
(US8952177, 123 | US9089569, 123)
Show SMILES Cc1cnc(COc2ccc3nc([C@@H]4CCCC[C@@H]4C(O)=O)n(Cc4c(F)cc(Br)cc4F)c3c2)c(F)c1
Show InChI InChI=1/C28H25BrF3N3O3/c1-15-8-23(32)25(33-12-15)14-38-17-6-7-24-26(11-17)35(13-20-21(30)9-16(29)10-22(20)31)27(34-24)18-4-2-3-5-19(18)28(36)37/h6-12,18-19H,2-5,13-14H2,1H3,(H,36,37)/t18-,19+/s2
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0.610n/an/an/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
FLAP-containing membranes were prepared as was a FITC-labeled FLAP modulator (3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-in...


US Patent US8952177 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM145769
PNG
(US8952177, 123 | US9089569, 123)
Show SMILES Cc1cnc(COc2ccc3nc([C@@H]4CCCC[C@@H]4C(O)=O)n(Cc4c(F)cc(Br)cc4F)c3c2)c(F)c1
Show InChI InChI=1/C28H25BrF3N3O3/c1-15-8-23(32)25(33-12-15)14-38-17-6-7-24-26(11-17)35(13-20-21(30)9-16(29)10-22(20)31)27(34-24)18-4-2-3-5-19(18)28(36)37/h6-12,18-19H,2-5,13-14H2,1H3,(H,36,37)/t18-,19+/s2
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0.610n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9089569 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase-activating protein (FLAP)


(Homo sapiens (Human))
BDBM145782
PNG
(US8952177, 136 | US9089569, 136)
Show SMILES CCC(CC)(Cc1nc2ccc(OCc3ncc(C)cc3F)cc2n1Cc1ccc(Br)cc1)C(O)=O
Show InChI InChI=1S/C28H29BrFN3O3/c1-4-28(5-2,27(34)35)14-26-32-23-11-10-21(36-17-24-22(30)12-18(3)15-31-24)13-25(23)33(26)16-19-6-8-20(29)9-7-19/h6-13,15H,4-5,14,16-17H2,1-3H3,(H,34,35)
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0.640n/an/an/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
FLAP-containing membranes were prepared as was a FITC-labeled FLAP modulator (3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-in...


US Patent US8952177 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM145782
PNG
(US8952177, 136 | US9089569, 136)
Show SMILES CCC(CC)(Cc1nc2ccc(OCc3ncc(C)cc3F)cc2n1Cc1ccc(Br)cc1)C(O)=O
Show InChI InChI=1S/C28H29BrFN3O3/c1-4-28(5-2,27(34)35)14-26-32-23-11-10-21(36-17-24-22(30)12-18(3)15-31-24)13-25(23)33(26)16-19-6-8-20(29)9-7-19/h6-13,15H,4-5,14,16-17H2,1-3H3,(H,34,35)
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0.640n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9089569 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase-activating protein (FLAP)


(Homo sapiens (Human))
BDBM145783
PNG
(US8952177, 137 | US9089569, 137)
Show SMILES Cc1cnc(COc2ccc3nc([C@H]4CCCC[C@H]4C(O)=O)n(Cc4c(F)cc(cc4F)-c4ccc(cc4)C(F)(F)F)c3c2)c(F)c1
Show InChI InChI=1/C35H29F6N3O3/c1-19-12-29(38)31(42-16-19)18-47-23-10-11-30-32(15-23)44(33(43-30)24-4-2-3-5-25(24)34(45)46)17-26-27(36)13-21(14-28(26)37)20-6-8-22(9-7-20)35(39,40)41/h6-16,24-25H,2-5,17-18H2,1H3,(H,45,46)/t24-,25+/s2
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0.660n/an/an/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
FLAP-containing membranes were prepared as was a FITC-labeled FLAP modulator (3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-in...


US Patent US8952177 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM145783
PNG
(US8952177, 137 | US9089569, 137)
Show SMILES Cc1cnc(COc2ccc3nc([C@H]4CCCC[C@H]4C(O)=O)n(Cc4c(F)cc(cc4F)-c4ccc(cc4)C(F)(F)F)c3c2)c(F)c1
Show InChI InChI=1/C35H29F6N3O3/c1-19-12-29(38)31(42-16-19)18-47-23-10-11-30-32(15-23)44(33(43-30)24-4-2-3-5-25(24)34(45)46)17-26-27(36)13-21(14-28(26)37)20-6-8-22(9-7-20)35(39,40)41/h6-16,24-25H,2-5,17-18H2,1H3,(H,45,46)/t24-,25+/s2
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0.660n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9089569 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM169421
PNG
(US9079866, 826)
Show SMILES CC(C)S(=O)(=O)c1ncccc1-c1ccc(c(F)c1)-c1cnc2[nH]ccc2c1
Show InChI InChI=1S/C21H18FN3O2S/c1-13(2)28(26,27)21-18(4-3-8-24-21)14-5-6-17(19(22)11-14)16-10-15-7-9-23-20(15)25-12-16/h3-13H,1-2H3,(H,23,25)
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0.700n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM169270
PNG
(US9079866, 675)
Show SMILES CC(C)(C)NS(=O)(=O)c1ccccc1-c1cnc(c(F)c1)-c1cnc(N)nc1
Show InChI InChI=1S/C19H20FN5O2S/c1-19(2,3)25-28(26,27)16-7-5-4-6-14(16)12-8-15(20)17(22-9-12)13-10-23-18(21)24-11-13/h4-11,25H,1-3H3,(H2,21,23,24)
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0.700n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM145657
PNG
(US8952177, 11 | US9089569, 11)
Show SMILES Cc1ccc(COc2ccc3nc([C@@H]4CCCC[C@@H]4C(O)=O)n(Cc4ccc(Br)cc4F)c3c2)nc1
Show InChI InChI=1/C28H27BrFN3O3/c1-17-6-9-20(31-14-17)16-36-21-10-11-25-26(13-21)33(15-18-7-8-19(29)12-24(18)30)27(32-25)22-4-2-3-5-23(22)28(34)35/h6-14,22-23H,2-5,15-16H2,1H3,(H,34,35)/t22-,23+/s2
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0.740n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9089569 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase-activating protein (FLAP)


(Homo sapiens (Human))
BDBM145657
PNG
(US8952177, 11 | US9089569, 11)
Show SMILES Cc1ccc(COc2ccc3nc([C@@H]4CCCC[C@@H]4C(O)=O)n(Cc4ccc(Br)cc4F)c3c2)nc1
Show InChI InChI=1/C28H27BrFN3O3/c1-17-6-9-20(31-14-17)16-36-21-10-11-25-26(13-21)33(15-18-7-8-19(29)12-24(18)30)27(32-25)22-4-2-3-5-23(22)28(34)35/h6-14,22-23H,2-5,15-16H2,1H3,(H,34,35)/t22-,23+/s2
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0.740n/an/an/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
FLAP-containing membranes were prepared as was a FITC-labeled FLAP modulator (3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-in...


US Patent US8952177 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase-activating protein (FLAP)


(Homo sapiens (Human))
BDBM145817
PNG
(US8952177, 173 | US8952177, 175 | US9089569, 175)
Show SMILES Cc1cnc(COc2ccc3nc([C@@H]4CCCC[C@@H]4C(O)=O)n(Cc4ccc(cc4F)N4CCC(F)CC4)c3c2)c(F)c1
Show InChI InChI=1/C33H35F3N4O3/c1-20-14-28(36)30(37-17-20)19-43-24-8-9-29-31(16-24)40(32(38-29)25-4-2-3-5-26(25)33(41)42)18-21-6-7-23(15-27(21)35)39-12-10-22(34)11-13-39/h6-9,14-17,22,25-26H,2-5,10-13,18-19H2,1H3,(H,41,42)/t25-,26+/s2
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0.820n/an/an/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
FLAP-containing membranes were prepared as was a FITC-labeled FLAP modulator (3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-in...


US Patent US8952177 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM145817
PNG
(US8952177, 173 | US8952177, 175 | US9089569, 175)
Show SMILES Cc1cnc(COc2ccc3nc([C@@H]4CCCC[C@@H]4C(O)=O)n(Cc4ccc(cc4F)N4CCC(F)CC4)c3c2)c(F)c1
Show InChI InChI=1/C33H35F3N4O3/c1-20-14-28(36)30(37-17-20)19-43-24-8-9-29-31(16-24)40(32(38-29)25-4-2-3-5-26(25)33(41)42)18-21-6-7-23(15-27(21)35)39-12-10-22(34)11-13-39/h6-9,14-17,22,25-26H,2-5,10-13,18-19H2,1H3,(H,41,42)/t25-,26+/s2
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0.820n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9089569 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase-activating protein (FLAP)


(Homo sapiens (Human))
BDBM145816
PNG
(US8952177, 172 | US9089569, 172)
Show SMILES Cc1cnc(COc2ccc3nc([C@@H]4CCCC[C@@H]4C(O)=O)n(Cc4c(F)cc(cc4F)N4CCC(F)CC4)c3c2)c(F)c1
Show InChI InChI=1/C33H34F4N4O3/c1-19-12-28(37)30(38-16-19)18-44-22-6-7-29-31(15-22)41(32(39-29)23-4-2-3-5-24(23)33(42)43)17-25-26(35)13-21(14-27(25)36)40-10-8-20(34)9-11-40/h6-7,12-16,20,23-24H,2-5,8-11,17-18H2,1H3,(H,42,43)/t23-,24+/s2
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0.840n/an/an/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
FLAP-containing membranes were prepared as was a FITC-labeled FLAP modulator (3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-in...


US Patent US8952177 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM145816
PNG
(US8952177, 172 | US9089569, 172)
Show SMILES Cc1cnc(COc2ccc3nc([C@@H]4CCCC[C@@H]4C(O)=O)n(Cc4c(F)cc(cc4F)N4CCC(F)CC4)c3c2)c(F)c1
Show InChI InChI=1/C33H34F4N4O3/c1-19-12-28(37)30(38-16-19)18-44-22-6-7-29-31(15-22)41(32(39-29)23-4-2-3-5-24(23)33(42)43)17-25-26(35)13-21(14-27(25)36)40-10-8-20(34)9-11-40/h6-7,12-16,20,23-24H,2-5,8-11,17-18H2,1H3,(H,42,43)/t23-,24+/s2
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0.840n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9089569 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM167188
PNG
(US9073876, 269)
Show SMILES CNc1nc(C)cc(Oc2c(F)c(ccc2C2CCC2)-c2cnc(N)cn2)n1
Show InChI InChI=1S/C20H21FN6O/c1-11-8-17(27-20(23-2)26-11)28-19-13(12-4-3-5-12)6-7-14(18(19)21)15-9-25-16(22)10-24-15/h6-10,12H,3-5H2,1-2H3,(H2,22,25)(H,23,26,27)
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0.900n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9073876 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM145807
PNG
(US8952177, 163 | US9089569, 163)
Show SMILES Cc1ccc(COc2ccc3nc([C@H]4CCCC[C@H]4C(O)=O)n(Cc4ccc(cc4F)N4CCC(F)(F)C4)c3c2)nc1
Show InChI InChI=1/C32H33F3N4O3/c1-20-6-8-22(36-16-20)18-42-24-10-11-28-29(15-24)39(30(37-28)25-4-2-3-5-26(25)31(40)41)17-21-7-9-23(14-27(21)33)38-13-12-32(34,35)19-38/h6-11,14-16,25-26H,2-5,12-13,17-19H2,1H3,(H,40,41)/t25-,26+/s2
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0.960n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9089569 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase-activating protein (FLAP)


(Homo sapiens (Human))
BDBM145807
PNG
(US8952177, 163 | US9089569, 163)
Show SMILES Cc1ccc(COc2ccc3nc([C@H]4CCCC[C@H]4C(O)=O)n(Cc4ccc(cc4F)N4CCC(F)(F)C4)c3c2)nc1
Show InChI InChI=1/C32H33F3N4O3/c1-20-6-8-22(36-16-20)18-42-24-10-11-28-29(15-24)39(30(37-28)25-4-2-3-5-26(25)31(40)41)17-21-7-9-23(14-27(21)33)38-13-12-32(34,35)19-38/h6-11,14-16,25-26H,2-5,12-13,17-19H2,1H3,(H,40,41)/t25-,26+/s2
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0.960n/an/an/an/an/an/an/an/a



Janssen Pharmaceutica NV

US Patent


Assay Description
FLAP-containing membranes were prepared as was a FITC-labeled FLAP modulator (3-(3-(tert-butylthio)-1-(4-chlorobenzyl)-5-(quinolin-2-ylmethoxy)-1H-in...


US Patent US8952177 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM168777
PNG
(US9079866, 175)
Show SMILES COC[C@H](C)NS(=O)(=O)c1ccccc1-c1ccc(c(F)c1)-c1cnc(N)cn1
Show InChI InChI=1/C20H21FN4O3S/c1-13(12-28-2)25-29(26,27)19-6-4-3-5-15(19)14-7-8-16(17(21)9-14)18-10-24-20(22)11-23-18/h3-11,13,25H,12H2,1-2H3,(H2,22,24)/t13-/s2
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1n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM168648
PNG
(US9079866, 22 | US9079866, 23)
Show SMILES Nc1cnc(cn1)-c1ccc(cc1F)-c1ccccc1S(=O)(=O)N[C@@H]1CCc2ccccc12
Show InChI InChI=1/C25H21FN4O2S/c26-21-13-17(9-11-20(21)23-14-29-25(27)15-28-23)19-7-3-4-8-24(19)33(31,32)30-22-12-10-16-5-1-2-6-18(16)22/h1-9,11,13-15,22,30H,10,12H2,(H2,27,29)/t22-/s2
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1n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM168649
PNG
(US9079866, 26)
Show SMILES Nc1cnc(cn1)-c1ccc(cc1F)-c1ccccc1S(=O)(=O)Nc1ccccc1
Show InChI InChI=1S/C22H17FN4O2S/c23-19-12-15(10-11-18(19)20-13-26-22(24)14-25-20)17-8-4-5-9-21(17)30(28,29)27-16-6-2-1-3-7-16/h1-14,27H,(H2,24,26)
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1n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM168670
PNG
(US9079866, 47)
Show SMILES CCN(CC)S(=O)(=O)c1ccccc1-c1ccc(c(F)c1)-c1cnc(N)cn1
Show InChI InChI=1S/C20H21FN4O2S/c1-3-25(4-2)28(26,27)19-8-6-5-7-15(19)14-9-10-16(17(21)11-14)18-12-24-20(22)13-23-18/h5-13H,3-4H2,1-2H3,(H2,22,24)
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1n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM168673
PNG
(US9079866, 50)
Show SMILES Nc1cnc(cn1)-c1ccc(cc1F)-c1ccccc1S(=O)(=O)N1CCCC(F)(F)C1
Show InChI InChI=1S/C21H19F3N4O2S/c22-17-10-14(6-7-16(17)18-11-27-20(25)12-26-18)15-4-1-2-5-19(15)31(29,30)28-9-3-8-21(23,24)13-28/h1-2,4-7,10-12H,3,8-9,13H2,(H2,25,27)
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1n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM168678
PNG
(US9079866, 55)
Show SMILES Nc1cnc(cn1)-c1ccc(cc1F)-c1ccccc1S(=O)(=O)N1CCC(O)(CC1)C(F)(F)F
Show InChI InChI=1S/C22H20F4N4O3S/c23-17-11-14(5-6-16(17)18-12-29-20(27)13-28-18)15-3-1-2-4-19(15)34(32,33)30-9-7-21(31,8-10-30)22(24,25)26/h1-6,11-13,31H,7-10H2,(H2,27,29)
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1n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM168691
PNG
(US9079866, 68)
Show SMILES Nc1cnc(cn1)-c1ccc(cc1F)-c1ccccc1S(=O)(=O)N1CCC(CO)CC1
Show InChI InChI=1S/C22H23FN4O3S/c23-19-11-16(5-6-18(19)20-12-26-22(24)13-25-20)17-3-1-2-4-21(17)31(29,30)27-9-7-15(14-28)8-10-27/h1-6,11-13,15,28H,7-10,14H2,(H2,24,26)
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1n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM168692
PNG
(US9079866, 69)
Show SMILES Nc1cnc(cn1)-c1ccc(cc1F)-c1ccccc1S(=O)(=O)N1CCC(CCO)CC1
Show InChI InChI=1S/C23H25FN4O3S/c24-20-13-17(5-6-19(20)21-14-27-23(25)15-26-21)18-3-1-2-4-22(18)32(30,31)28-10-7-16(8-11-28)9-12-29/h1-6,13-16,29H,7-12H2,(H2,25,27)
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1n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM168701
PNG
(US9079866, 78)
Show SMILES Nc1cnc(cn1)-c1ccc(cc1F)-c1ccccc1S(=O)(=O)N[C@@H](CO)[C@@H](O)c1ccccc1
Show InChI InChI=1/C25H23FN4O4S/c26-20-12-17(10-11-19(20)21-13-29-24(27)14-28-21)18-8-4-5-9-23(18)35(33,34)30-22(15-31)25(32)16-6-2-1-3-7-16/h1-14,22,25,30-32H,15H2,(H2,27,29)/t22-,25-/s2
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1n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM168705
PNG
(US9079866, 82)
Show SMILES Nc1cnc(cn1)-c1ccc(cc1F)-c1ccccc1S(=O)(=O)N[C@@H](CO)c1ccccc1
Show InChI InChI=1/C24H21FN4O3S/c25-20-12-17(10-11-19(20)21-13-28-24(26)14-27-21)18-8-4-5-9-23(18)33(31,32)29-22(15-30)16-6-2-1-3-7-16/h1-14,22,29-30H,15H2,(H2,26,28)/t22-/s2
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1n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM168706
PNG
(US9079866, 83)
Show SMILES C[C@H](NS(=O)(=O)c1ccccc1-c1ccc(c(F)c1)-c1cnc(N)cn1)[C@@H](O)c1ccccc1
Show InChI InChI=1/C25H23FN4O3S/c1-16(25(31)17-7-3-2-4-8-17)30-34(32,33)23-10-6-5-9-19(23)18-11-12-20(21(26)13-18)22-14-29-24(27)15-28-22/h2-16,25,30-31H,1H3,(H2,27,29)/t16-,25+/s2
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1n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM168631
PNG
(US9079866, 4)
Show SMILES CC(C)(C)NS(=O)(=O)c1ccccc1-c1ccc(c(F)c1)-c1cnc(N)cn1
Show InChI InChI=1S/C20H21FN4O2S/c1-20(2,3)25-28(26,27)18-7-5-4-6-14(18)13-8-9-15(16(21)10-13)17-11-24-19(22)12-23-17/h4-12,25H,1-3H3,(H2,22,24)
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1n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM168633
PNG
(US9079866, 6)
Show SMILES Nc1cnc(cn1)-c1ccc(cc1F)-c1ccccc1S(=O)(=O)NC1CCCCC1
Show InChI InChI=1S/C22H23FN4O2S/c23-19-12-15(10-11-18(19)20-13-26-22(24)14-25-20)17-8-4-5-9-21(17)30(28,29)27-16-6-2-1-3-7-16/h4-5,8-14,16,27H,1-3,6-7H2,(H2,24,26)
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1n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM168635
PNG
(US9079866, 8)
Show SMILES CC(NS(=O)(=O)c1ccccc1-c1ccc(c(F)c1)-c1cnc(N)cn1)C(F)(F)F
Show InChI InChI=1/C19H16F4N4O2S/c1-11(19(21,22)23)27-30(28,29)17-5-3-2-4-13(17)12-6-7-14(15(20)8-12)16-9-26-18(24)10-25-16/h2-11,27H,1H3,(H2,24,26)
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1n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM168640
PNG
(US9079866, 13)
Show SMILES CC(C)(NS(=O)(=O)c1ccccc1-c1ccc(c(F)c1)-c1cnc(N)cn1)C(F)(F)F
Show InChI InChI=1S/C20H18F4N4O2S/c1-19(2,20(22,23)24)28-31(29,30)17-6-4-3-5-13(17)12-7-8-14(15(21)9-12)16-10-27-18(25)11-26-16/h3-11,28H,1-2H3,(H2,25,27)
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1n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM60470
PNG
(BDBM168646 | US9079866, 127)
Show SMILES C[C@@H](NS(=O)(=O)c1ccccc1-c1ccc(c(F)c1)-c1cnc(N)cn1)C(F)(F)F
Show InChI InChI=1/C19H16F4N4O2S/c1-11(19(21,22)23)27-30(28,29)17-5-3-2-4-13(17)12-6-7-14(15(20)8-12)16-9-26-18(24)10-25-16/h2-11,27H,1H3,(H2,24,26)/t11-/s2
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1n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM167001
PNG
(US9073876, 87)
Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(Oc2nccc(n2)-c2ccccc2)c1F
Show InChI InChI=1S/C24H20FN5O/c25-22-18(20-13-29-21(26)14-28-20)10-9-17(15-7-4-8-15)23(22)31-24-27-12-11-19(30-24)16-5-2-1-3-6-16/h1-3,5-6,9-15H,4,7-8H2,(H2,26,29)
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1n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9073876 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM167005
PNG
(US9073876, 91)
Show SMILES Nc1cnc(cn1)-c1ccc(C2CCC2)c(Oc2nccc(n2)-c2cccs2)c1F
Show InChI InChI=1S/C22H18FN5OS/c23-20-15(17-11-27-19(24)12-26-17)7-6-14(13-3-1-4-13)21(20)29-22-25-9-8-16(28-22)18-5-2-10-30-18/h2,5-13H,1,3-4H2,(H2,24,27)
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1n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9073876 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM167014
PNG
(US9073876, 100)
Show SMILES COc1nc(N)cc(Oc2c(F)c(ccc2C2CCC2)-c2cnc(N)cn2)n1
Show InChI InChI=1S/C19H19FN6O2/c1-27-19-25-14(21)7-16(26-19)28-18-11(10-3-2-4-10)5-6-12(17(18)20)13-8-24-15(22)9-23-13/h5-10H,2-4H2,1H3,(H2,22,24)(H2,21,25,26)
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1n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9073876 (2015)

More data for this
Ligand-Target Pair
5-lipoxygenase/FLAP


(Homo sapiens (Human))
BDBM60476
PNG
(US9079866, 150)
Show SMILES CC(C)(C)[C@H](CO)NS(=O)(=O)c1ccccc1-c1ccc(c(F)c1)-c1cnc(N)cn1
Show InChI InChI=1/C22H25FN4O3S/c1-22(2,3)20(13-28)27-31(29,30)19-7-5-4-6-15(19)14-8-9-16(17(23)10-14)18-11-26-21(24)12-25-18/h4-12,20,27-28H,13H2,1-3H3,(H2,24,26)/t20-/s2
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1n/an/an/an/an/an/an/an/a



JANSSEN PHARMACEUTICA NV

US Patent


Assay Description
The assay below is used to test the modulatory activity of compounds against FLAP. Human and mouse FLAP-encoding DNA was amplified by polymerase chai...


US Patent US9079866 (2015)

More data for this
Ligand-Target Pair
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