Target/Host (Institution) | Ligand | Target/Host Links | Ligand Links | Trg + Lig Links | Ki nM | ΔG° kJ/mole | IC50 nM | Kd nM | EC50/IC50 nM | koff s-1 | kon M-1s-1 | pH | Temp °C |
---|---|---|---|---|---|---|---|---|---|---|---|---|---|
ALK tyrosine kinase receptor (F1174L) (Homo sapiens (Human)) | BDBM261689![]() (US9708295, 30) | PDB UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 2.60 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd US Patent | US Patent US9708295 (2017) BindingDB Entry DOI: 10.7270/Q2GM899Z | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (F1174L) (Homo sapiens (Human)) | BDBM261711![]() (US9708295, 53) | PDB UniProtKB/TrEMBL GoogleScholar | PC cid PC sid UniChem | US Patent | 3.10 | n/a | n/a | n/a | n/a | n/a | n/a | n/a | n/a |
Chia Tai Tianqing Pharmaceutical Group Co., Ltd US Patent | US Patent US9708295 (2017) BindingDB Entry DOI: 10.7270/Q2GM899Z | ||||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (F1174L) (Homo sapiens (Human)) | BDBM199945![]() (US9226923, 3) | PDB UniProtKB/TrEMBL GoogleScholar | Purchase PC cid PC sid UniChem | US Patent | n/a | n/a | 1.40 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing Allgen Pharma Co. Ltd. US Patent | Assay Description The inhibitory activities of compounds of Formula I were assay at Reaction Biology Corporation, One Great Valley Parkway, Malvern, Pa., USA. Human ... | US Patent US9226923 (2016) BindingDB Entry DOI: 10.7270/Q2JQ0ZT5 | |||||||||||
More data for this Ligand-Target Pair | |||||||||||||
ALK tyrosine kinase receptor (F1174L) (Homo sapiens (Human)) | BDBM50306682![]() ((R)-3-(1-(2,6-dichloro-3-fluorophenyl)ethoxy)-5-(1...) | PDB UniProtKB/TrEMBL GoogleScholar | Purchase CHEBI CHEMBL DrugBank MMDB PC cid PC sid PDB UniChem Patents Similars | PDB US Patent | n/a | n/a | 2.70 | n/a | n/a | n/a | n/a | n/a | n/a |
Nanjing Allgen Pharma Co. Ltd. US Patent | Assay Description The inhibitory activities of compounds of Formula I were assay at Reaction Biology Corporation, One Great Valley Parkway, Malvern, Pa., USA. Human ... | US Patent US9226923 (2016) BindingDB Entry DOI: 10.7270/Q2JQ0ZT5 | |||||||||||
More data for this Ligand-Target Pair | ![]() 3D Structure (crystal) |