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Compile Data Set for Download or QSAR

Found 3 hits Enz. Inhib. hit(s) with Target = 'AMP-activated protein kinase, alpha-2 subunit' AND taxid = 10116   
Target
(Institution)
LigandTarget
Links
Ligand
Links
Trg + Lig
Links
Ki
nM
ΔG°
kJ/mole
IC50
nM
Kd
nM
EC50/IC50
nM
koff
s-1
kon
M-1s-1
pHTemp
°C
AMP-activated protein kinase, alpha-2 subunit


(Rattus norvegicus)
BDBM50436622
PNG
(CHEMBL568708)
Show SMILES CCOc1ccc2nc(S)sc2c1
Show InChI InChI=1S/C9H9NOS2/c1-2-11-6-3-4-7-8(5-6)13-9(12)10-7/h3-5H,2H2,1H3,(H,10,12)
PDB
MMDB

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CHEMBL
PC cid
PC sid
UniChem
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Article
PubMed
n/an/an/an/a 7.61E+4n/an/an/an/a



Bar Ilan University

Curated by ChEMBL


Assay Description
Activation of AMPK in rat L6 cells assessed as increase of [3H]dGlc uptake after 5 hrs


Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase, alpha-2 subunit


(Rattus norvegicus)
BDBM50436624
PNG
(CHEMBL1522339)
Show SMILES CCc1sc(N)nc1O
Show InChI InChI=1S/C5H8N2OS/c1-2-3-4(8)7-5(6)9-3/h8H,2H2,1H3,(H2,6,7)
PDB
MMDB

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UniProtKB/SwissProt

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CHEMBL
PC cid
PC sid
UniChem
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Article
PubMed
n/an/an/an/a 6.15E+4n/an/an/an/a



Bar Ilan University

Curated by ChEMBL


Assay Description
Activation of AMPK in rat L6 cells assessed as increase of [3H]dGlc uptake after 5 hrs


Citation and Details
More data for this
Ligand-Target Pair
AMP-activated protein kinase, alpha-2 subunit


(Rattus norvegicus)
BDBM50436623
PNG
(CHEMBL2398100)
Show SMILES Brc1ccc2[nH]c(=O)sc2c1
Show InChI InChI=1S/C7H4BrNOS/c8-4-1-2-5-6(3-4)11-7(10)9-5/h1-3H,(H,9,10)
PDB
MMDB

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KEGG

UniProtKB/SwissProt

B.MOAD
GoogleScholar
AffyNet 
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CHEMBL
PC cid
PC sid
UniChem
AffyNet 
Article
PubMed
n/an/an/an/a 7.29E+4n/an/an/an/a



Bar Ilan University

Curated by ChEMBL


Assay Description
Activation of AMPK in rat L6 cells assessed as increase of [3H]dGlc uptake after 5 hrs


Citation and Details
More data for this
Ligand-Target Pair