Compile Data Set for Download or QSAR

Found 415 hits Enz. Inhib. hit(s) with Target = 'Acetyl-CoA carboxylase 2 (ACC2)'   

Target/Host (Institution)	Ligand	Target/Host Links	Ligand Links	Trg + Lig Links	Ki nM	ΔG° kJ/mole	IC50 nM	Kd nM	EC50/IC50 nM	koff s-1	kon M-1s-1	pH	Temp °C
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM97610 (CHEMBL1630715 | US8470841, 35) Show SMILES CC(C)Oc1ccc(Oc2ccc(CC[C@H](C)NC(C)=O)cc2)cn1 Show InChI InChI=1S/C20H26N2O3/c1-14(2)24-20-12-11-19(13-21-20)25-18-9-7-17(8-10-18)6-5-15(3)22-16(4)23/h7-15H,5-6H2,1-4H3,(H,22,23)/t15-/m0/s1	PDB MMDB B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	30	n/a	n/a	n/a	n/a	7.5	37
Sanofi US Patent					Assay Description the enzymatic activity of ACC and its inhibition by test substances were determined by a luminometric assay.				US Patent US8470841 (2013) BindingDB Entry DOI: 10.7270/Q2183537
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM101974 (US8530460, 1.54) Show SMILES C[C@H](NC(C)=O)c1ccc(OC2CN(C2)c2ccc(OCC3CC3(F)F)cc2F)cc1 Show InChI InChI=1S/C23H25F3N2O3/c1-14(27-15(2)29)16-3-5-18(6-4-16)31-20-11-28(12-20)22-8-7-19(9-21(22)24)30-13-17-10-23(17,25)26/h3-9,14,17,20H,10-13H2,1-2H3,(H,27,29)/t14-,17?/m0/s1	PDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	40	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Enzyme assay using human acetyl-CoA carboxylase 2 (ACC).				US Patent US8530460 (2013) BindingDB Entry DOI: 10.7270/Q2X34W3N
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM212757 (US9278954, 7.1) Show SMILES CCNC(=O)C(C)c1ccc(O[C@@H]2CCN(C2)c2ccc(OC3CCC3)cc2)cc1 Show InChI InChI=1S/C25H32N2O3/c1-3-26-25(28)18(2)19-7-11-22(12-8-19)30-24-15-16-27(17-24)20-9-13-23(14-10-20)29-21-5-4-6-21/h7-14,18,21,24H,3-6,15-17H2,1-2H3,(H,26,28)/t18?,24-/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	41	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM212754 (US9278954, 6.8 isomer 1 | US9278954, 6.8 isomer 2 ...) Show SMILES CCCOc1ccc(cc1)N1CC[C@H](C1)Oc1ccc(cc1)C(C)C(=O)NCC Show InChI InChI=1S/C24H32N2O3/c1-4-16-28-21-12-8-20(9-13-21)26-15-14-23(17-26)29-22-10-6-19(7-11-22)18(3)24(27)25-5-2/h6-13,18,23H,4-5,14-17H2,1-3H3,(H,25,27)/t18?,23-/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	43	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM97600 (US8470841, 12) Show SMILES CC(CCc1ccc(Oc2ccc(OCC3CCC3)cn2)cc1)NC(C)=O Show InChI InChI=1S/C22H28N2O3/c1-16(24-17(2)25)6-7-18-8-10-20(11-9-18)27-22-13-12-21(14-23-22)26-15-19-4-3-5-19/h8-14,16,19H,3-7,15H2,1-2H3,(H,24,25)	PDB MMDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	7.5	37
Sanofi US Patent					Assay Description the enzymatic activity of ACC and its inhibition by test substances were determined by a luminometric assay.				US Patent US8470841 (2013) BindingDB Entry DOI: 10.7270/Q2183537
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM97601 (US8470841, 17) Show SMILES CC(=O)NCCC[C@H]1OC[C@@H](CO1)Oc1ccc(OCc2ccccc2)cn1 Show InChI InChI=1S/C21H26N2O5/c1-16(24)22-11-5-8-21-26-14-19(15-27-21)28-20-10-9-18(12-23-20)25-13-17-6-3-2-4-7-17/h2-4,6-7,9-10,12,19,21H,5,8,11,13-15H2,1H3,(H,22,24)/t19-,21-	PDB MMDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	7.5	37
Sanofi US Patent					Assay Description the enzymatic activity of ACC and its inhibition by test substances were determined by a luminometric assay.				US Patent US8470841 (2013) BindingDB Entry DOI: 10.7270/Q2183537
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM102069 (US8530460, 8.7) Show SMILES CCOc1ccc(cc1)N1CC(C1)Oc1ccc(cc1)[C@H](C)NC(=O)c1cn[nH]c1 Show InChI InChI=1S/C23H26N4O3/c1-3-29-20-10-6-19(7-11-20)27-14-22(15-27)30-21-8-4-17(5-9-21)16(2)26-23(28)18-12-24-25-13-18/h4-13,16,22H,3,14-15H2,1-2H3,(H,24,25)(H,26,28)/t16-/m0/s1	PDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	50	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Enzyme assay using human acetyl-CoA carboxylase 2 (ACC).				US Patent US8530460 (2013) BindingDB Entry DOI: 10.7270/Q2X34W3N
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Rattus norvegicus (Rat))	BDBM50189617 ((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...) Show SMILES O=C([C@@H]1CCCN(C1)C1CCN(CC1)C(=O)c1c2ccccc2cc2ccccc12)N1CCOCC1 Show InChI InChI=1S/C30H35N3O3/c34-29(32-16-18-36-19-17-32)24-8-5-13-33(21-24)25-11-14-31(15-12-25)30(35)28-26-9-3-1-6-22(26)20-23-7-2-4-10-27(23)28/h1-4,6-7,9-10,20,24-25H,5,8,11-19,21H2/t24-/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar	Purchase CHEBI CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	55	n/a	n/a	n/a	n/a	n/a	n/a
Torrent Pharmaceuticals Ltd Curated by ChEMBL					Assay Description Inhibition of rat acetyl-CoA carboxylase 2				Bioorg Med Chem Lett 19: 949-53 (2009) Article DOI: 10.1016/j.bmcl.2008.11.099 BindingDB Entry DOI: 10.7270/Q25T3KB3
					More data for this Ligand-Target Pair				3D Structure (crystal)
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM212610 (US9278954, 1.1 | US9278954, 6.1 isomer 1 | US92789...) Show SMILES CC(C(=O)NC1CC1)c1ccc(O[C@@H]2CCN(C2)c2ncnc(OCC(C)(C)O)c2Cl)cc1 Show InChI InChI=1S/C24H31ClN4O4/c1-15(22(30)28-17-6-7-17)16-4-8-18(9-5-16)33-19-10-11-29(12-19)21-20(25)23(27-14-26-21)32-13-24(2,3)31/h4-5,8-9,14-15,17,19,31H,6-7,10-13H2,1-3H3,(H,28,30)/t15?,19-/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	57	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM101955 (US8530460, 1.35) Show SMILES CCCOc1ccc(cc1)N1CC(C1)Oc1ccc(cc1)[C@H](C)NC(=O)C1CC1 Show InChI InChI=1S/C24H30N2O3/c1-3-14-28-21-12-8-20(9-13-21)26-15-23(16-26)29-22-10-6-18(7-11-22)17(2)25-24(27)19-4-5-19/h6-13,17,19,23H,3-5,14-16H2,1-2H3,(H,25,27)/t17-/m0/s1	PDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Enzyme assay using human acetyl-CoA carboxylase 2 (ACC).				US Patent US8530460 (2013) BindingDB Entry DOI: 10.7270/Q2X34W3N
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM97609 (US8470841, 33) Show SMILES CC(C)Oc1ccc(Oc2ccc(CCC(C)NC(C)=O)cc2)cn1 Show InChI InChI=1S/C20H26N2O3/c1-14(2)24-20-12-11-19(13-21-20)25-18-9-7-17(8-10-18)6-5-15(3)22-16(4)23/h7-15H,5-6H2,1-4H3,(H,22,23)	PDB MMDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	7.5	37
Sanofi US Patent					Assay Description the enzymatic activity of ACC and its inhibition by test substances were determined by a luminometric assay.				US Patent US8470841 (2013) BindingDB Entry DOI: 10.7270/Q2183537
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM101985 (US8530460, 2.2) Show SMILES C[C@H](NC(C)=O)c1ccc(OC2CN(C2)c2ccc(OCC3CC3)cc2F)cc1 Show InChI InChI=1S/C23H27FN2O3/c1-15(25-16(2)27)18-5-7-19(8-6-18)29-21-12-26(13-21)23-10-9-20(11-22(23)24)28-14-17-3-4-17/h5-11,15,17,21H,3-4,12-14H2,1-2H3,(H,25,27)/t15-/m0/s1	PDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	60	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Enzyme assay using human acetyl-CoA carboxylase 2 (ACC).				US Patent US8530460 (2013) BindingDB Entry DOI: 10.7270/Q2X34W3N
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Rattus norvegicus (Rat))	BDBM50189617 ((3R)-1'-(9-anthrylcarbonyl)-3-(morpholin-4-ylcarbo...) Show SMILES O=C([C@@H]1CCCN(C1)C1CCN(CC1)C(=O)c1c2ccccc2cc2ccccc12)N1CCOCC1 Show InChI InChI=1S/C30H35N3O3/c34-29(32-16-18-36-19-17-32)24-8-5-13-33(21-24)25-11-14-31(15-12-25)30(35)28-26-9-3-1-6-22(26)20-23-7-2-4-10-27(23)28/h1-4,6-7,9-10,20,24-25H,5,8,11-19,21H2/t24-/m1/s1	PDB MMDB UniProtKB/TrEMBL B.MOAD GoogleScholar	Purchase CHEBI CHEMBL MMDB PC cid PC sid PDB UniChem Patents Similars	PDB Article PubMed	n/a	n/a	61	n/a	n/a	n/a	n/a	n/a	n/a
Taisho Pharmaceutical Co., Ltd Curated by ChEMBL					Assay Description Inhibition of rat ACC2				Bioorg Med Chem Lett 19: 6645-8 (2009) Article DOI: 10.1016/j.bmcl.2009.10.012 BindingDB Entry DOI: 10.7270/Q2ZP468S
					More data for this Ligand-Target Pair				3D Structure (crystal)
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM212611 (US9278954, 1.2) Show SMILES CCCNc1nccc(N2CC[C@H](C2)Oc2ccc(cc2)C(C)C(=O)NC2CC2)c1F Show InChI InChI=1S/C24H31FN4O2/c1-3-12-26-23-22(25)21(10-13-27-23)29-14-11-20(15-29)31-19-8-4-17(5-9-19)16(2)24(30)28-18-6-7-18/h4-5,8-10,13,16,18,20H,3,6-7,11-12,14-15H2,1-2H3,(H,26,27)(H,28,30)/t16?,20-/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	61	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM97611 (CHEMBL1630712 | US8470841, 36) Show SMILES CC(CCc1ccc(Oc2ccc(OCc3ccccc3)nc2)cc1)NC(C)=O Show InChI InChI=1S/C24H26N2O3/c1-18(26-19(2)27)8-9-20-10-12-22(13-11-20)29-23-14-15-24(25-16-23)28-17-21-6-4-3-5-7-21/h3-7,10-16,18H,8-9,17H2,1-2H3,(H,26,27)	PDB MMDB B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	7.5	37
Sanofi US Patent					Assay Description the enzymatic activity of ACC and its inhibition by test substances were determined by a luminometric assay.				US Patent US8470841 (2013) BindingDB Entry DOI: 10.7270/Q2183537
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM101934 (US8530460, 1.14) Show SMILES C[C@H](NC(C)=O)c1ccc(OC2CN(C2)c2ccc(OCC3CC3)cc2)cc1 Show InChI InChI=1S/C23H28N2O3/c1-16(24-17(2)26)19-5-9-22(10-6-19)28-23-13-25(14-23)20-7-11-21(12-8-20)27-15-18-3-4-18/h5-12,16,18,23H,3-4,13-15H2,1-2H3,(H,24,26)/t16-/m0/s1	PDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Enzyme assay using human acetyl-CoA carboxylase 2 (ACC).				US Patent US8530460 (2013) BindingDB Entry DOI: 10.7270/Q2X34W3N
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM101933 (US8530460, 1.13) Show SMILES CCCOc1ccc(cc1)N1CC(C1)Oc1ccc(cc1)[C@H](C)NC(C)=O Show InChI InChI=1S/C22H28N2O3/c1-4-13-26-20-11-7-19(8-12-20)24-14-22(15-24)27-21-9-5-18(6-10-21)16(2)23-17(3)25/h5-12,16,22H,4,13-15H2,1-3H3,(H,23,25)/t16-/m0/s1	PDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	70	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Enzyme assay using human acetyl-CoA carboxylase 2 (ACC).				US Patent US8530460 (2013) BindingDB Entry DOI: 10.7270/Q2X34W3N
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM212759 (US9278954, 7.2) Show SMILES CCNC(=O)C(C)c1ccc(O[C@@H]2CCN(C2)c2ccc(OC3CCCC3)cc2)cc1 Show InChI InChI=1S/C26H34N2O3/c1-3-27-26(29)19(2)20-8-12-23(13-9-20)31-25-16-17-28(18-25)21-10-14-24(15-11-21)30-22-6-4-5-7-22/h8-15,19,22,25H,3-7,16-18H2,1-2H3,(H,27,29)/t19?,25-/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	72	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM212754 (US9278954, 6.8 isomer 1 | US9278954, 6.8 isomer 2 ...) Show SMILES CCCOc1ccc(cc1)N1CC[C@H](C1)Oc1ccc(cc1)C(C)C(=O)NCC Show InChI InChI=1S/C24H32N2O3/c1-4-16-28-21-12-8-20(9-13-21)26-15-14-23(17-26)29-22-10-6-19(7-11-22)18(3)24(27)25-5-2/h6-13,18,23H,4-5,14-17H2,1-3H3,(H,25,27)/t18?,23-/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	75	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM97623 (US8470841, 52) Show SMILES CC(C)Oc1ccc(OC2CCC(CCC(C)NC(C)=O)CC2)cn1 Show InChI InChI=1S/C20H32N2O3/c1-14(2)24-20-12-11-19(13-21-20)25-18-9-7-17(8-10-18)6-5-15(3)22-16(4)23/h11-15,17-18H,5-10H2,1-4H3,(H,22,23)	PDB MMDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	7.5	37
Sanofi US Patent					Assay Description the enzymatic activity of ACC and its inhibition by test substances were determined by a luminometric assay.				US Patent US8470841 (2013) BindingDB Entry DOI: 10.7270/Q2183537
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM101926 (US8530460, 1.6) Show SMILES CC(NC(C)=O)c1ccc(OC2CN(C2)c2ccc(OC3CCCC3)cc2)cc1 Show InChI InChI=1S/C24H30N2O3/c1-17(25-18(2)27)19-7-11-22(12-8-19)29-24-15-26(16-24)20-9-13-23(14-10-20)28-21-5-3-4-6-21/h7-14,17,21,24H,3-6,15-16H2,1-2H3,(H,25,27)	PDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Enzyme assay using human acetyl-CoA carboxylase 2 (ACC).				US Patent US8530460 (2013) BindingDB Entry DOI: 10.7270/Q2X34W3N
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM97622 (CHEMBL1630701 | US8470841, 51) Show SMILES CC(C)Oc1ccc(Oc2ccc(CC[C@H](C)NC(=O)C3CC3)cc2)cn1 Show InChI InChI=1S/C22H28N2O3/c1-15(2)26-21-13-12-20(14-23-21)27-19-10-6-17(7-11-19)5-4-16(3)24-22(25)18-8-9-18/h6-7,10-16,18H,4-5,8-9H2,1-3H3,(H,24,25)/t16-/m0/s1	PDB MMDB B.MOAD GoogleScholar	CHEMBL PC cid PC sid UniChem Similars	US Patent	n/a	n/a	80	n/a	n/a	n/a	n/a	7.5	37
Sanofi US Patent					Assay Description the enzymatic activity of ACC and its inhibition by test substances were determined by a luminometric assay.				US Patent US8470841 (2013) BindingDB Entry DOI: 10.7270/Q2183537
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM212615 (BDBM212741 | US9278954, 1.6 | US9278954, 1.9) Show SMILES CC(C(=O)NC1CC1C)c1ccc(O[C@@H]2CCN(C2)c2nc(ncc2F)N(C)C)cc1 Show InChI InChI=1S/C23H30FN5O2/c1-14-11-20(14)26-22(30)15(2)16-5-7-17(8-6-16)31-18-9-10-29(13-18)21-19(24)12-25-23(27-21)28(3)4/h5-8,12,14-15,18,20H,9-11,13H2,1-4H3,(H,26,30)/t14?,15?,18-,20?/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	86	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM101989 (US8530460, 2.6) Show SMILES CCCOc1ccc(N2CC(C2)Oc2ccc(cc2)[C@H](C)NC(C)=O)c(Cl)c1 Show InChI InChI=1S/C22H27ClN2O3/c1-4-11-27-19-9-10-22(21(23)12-19)25-13-20(14-25)28-18-7-5-17(6-8-18)15(2)24-16(3)26/h5-10,12,15,20H,4,11,13-14H2,1-3H3,(H,24,26)/t15-/m0/s1	PDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Enzyme assay using human acetyl-CoA carboxylase 2 (ACC).				US Patent US8530460 (2013) BindingDB Entry DOI: 10.7270/Q2X34W3N
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM101972 (US8530460, 1.52) Show SMILES CCCOc1ccc(nc1)N1CC(C1)Oc1ccc(cc1)[C@H](C)NC(C)=O Show InChI InChI=1S/C21H27N3O3/c1-4-11-26-19-9-10-21(22-12-19)24-13-20(14-24)27-18-7-5-17(6-8-18)15(2)23-16(3)25/h5-10,12,15,20H,4,11,13-14H2,1-3H3,(H,23,25)/t15-/m0/s1	PDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Enzyme assay using human acetyl-CoA carboxylase 2 (ACC).				US Patent US8530460 (2013) BindingDB Entry DOI: 10.7270/Q2X34W3N
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM101939 (US8530460, 1.19) Show SMILES CCOc1ccc(cc1)N1CC(C1)Oc1ccc(cc1)[C@H](C)NC(C)=O Show InChI InChI=1S/C21H26N2O3/c1-4-25-19-11-7-18(8-12-19)23-13-21(14-23)26-20-9-5-17(6-10-20)15(2)22-16(3)24/h5-12,15,21H,4,13-14H2,1-3H3,(H,22,24)/t15-/m0/s1	PDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Enzyme assay using human acetyl-CoA carboxylase 2 (ACC).				US Patent US8530460 (2013) BindingDB Entry DOI: 10.7270/Q2X34W3N
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM97615 (US8470841, 44) Show SMILES CC(C)Oc1ccc(Oc2ccc(CCC(C)NC(=O)C3CC3)cc2)cn1 Show InChI InChI=1S/C22H28N2O3/c1-15(2)26-21-13-12-20(14-23-21)27-19-10-6-17(7-11-19)5-4-16(3)24-22(25)18-8-9-18/h6-7,10-16,18H,4-5,8-9H2,1-3H3,(H,24,25)	PDB MMDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	7.5	37
Sanofi US Patent					Assay Description the enzymatic activity of ACC and its inhibition by test substances were determined by a luminometric assay.				US Patent US8470841 (2013) BindingDB Entry DOI: 10.7270/Q2183537
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM102055 (US8530460, 6.1) Show SMILES C[C@H](NC(C)=O)c1ccc(OC2CN(C2)c2ncc(cn2)-c2ccc(F)cc2)cc1 Show InChI InChI=1S/C23H23FN4O2/c1-15(27-16(2)29)17-5-9-21(10-6-17)30-22-13-28(14-22)23-25-11-19(12-26-23)18-3-7-20(24)8-4-18/h3-12,15,22H,13-14H2,1-2H3,(H,27,29)/t15-/m0/s1	PDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	90	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Enzyme assay using human acetyl-CoA carboxylase 2 (ACC).				US Patent US8530460 (2013) BindingDB Entry DOI: 10.7270/Q2X34W3N
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM212626 (BDBM212745 | US9278954, 1.17) Show SMILES CCNC(=O)C(C)c1ccc(O[C@@H]2CCN(C2)c2ncnc(OCC(C)(C)O)c2Cl)cc1 Show InChI InChI=1S/C23H31ClN4O4/c1-5-25-21(29)15(2)16-6-8-17(9-7-16)32-18-10-11-28(12-18)20-19(24)22(27-14-26-20)31-13-23(3,4)30/h6-9,14-15,18,30H,5,10-13H2,1-4H3,(H,25,29)/t15?,18-/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	95	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM212703 (US9278954, 2.1) Show SMILES CCNC(=O)C(C)c1ccc(O[C@@H]2CCN(C2)c2ccnc(n2)N(CC)CC)cc1 Show InChI InChI=1S/C23H33N5O2/c1-5-24-22(29)17(4)18-8-10-19(11-9-18)30-20-13-15-28(16-20)21-12-14-25-23(26-21)27(6-2)7-3/h8-12,14,17,20H,5-7,13,15-16H2,1-4H3,(H,24,29)/t17?,20-/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	95	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM64583 (BDBM50332551 | US8470841, 19) Show SMILES C[C@@H](CCc1ccc(Oc2ccc(OCc3ccccc3)cn2)cc1)NC(C)=O Show InChI InChI=1S/C24H26N2O3/c1-18(26-19(2)27)8-9-20-10-12-22(13-11-20)29-24-15-14-23(16-25-24)28-17-21-6-4-3-5-7-21/h3-7,10-16,18H,8-9,17H2,1-2H3,(H,26,27)/t18-/m0/s1	PDB MMDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	7.5	37
Sanofi US Patent					Assay Description the enzymatic activity of ACC and its inhibition by test substances were determined by a luminometric assay.				US Patent US8470841 (2013) BindingDB Entry DOI: 10.7270/Q2183537
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM102038 (US8530460, 4.32) Show SMILES C[C@H](NC(C)=O)c1ccc(OC2CN(C2)c2ccc(Cl)c(n2)C(F)(F)F)cc1 Show InChI InChI=1S/C19H19ClF3N3O2/c1-11(24-12(2)27)13-3-5-14(6-4-13)28-15-9-26(10-15)17-8-7-16(20)18(25-17)19(21,22)23/h3-8,11,15H,9-10H2,1-2H3,(H,24,27)/t11-/m0/s1	PDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Enzyme assay using human acetyl-CoA carboxylase 2 (ACC).				US Patent US8530460 (2013) BindingDB Entry DOI: 10.7270/Q2X34W3N
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM102129 (US8530460, 13) Show SMILES CC(NC(C)=O)c1ccc(OC2CN(C2)c2ccc(OCC3CC3)cc2)c(F)c1 Show InChI InChI=1S/C23H27FN2O3/c1-15(25-16(2)27)18-5-10-23(22(24)11-18)29-21-12-26(13-21)19-6-8-20(9-7-19)28-14-17-3-4-17/h5-11,15,17,21H,3-4,12-14H2,1-2H3,(H,25,27)	PDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	100	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Enzyme assay using human acetyl-CoA carboxylase 2 (ACC).				US Patent US8530460 (2013) BindingDB Entry DOI: 10.7270/Q2X34W3N
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM212612 (US9278954, 1.3 | US9278954, 1.4) Show SMILES CCCNc1nccc(N2CC[C@H](C2)Oc2ccc(cc2)C(C)C(=O)NC2CC2C)c1F Show InChI InChI=1S/C25H33FN4O2/c1-4-11-27-24-23(26)22(9-12-28-24)30-13-10-20(15-30)32-19-7-5-18(6-8-19)17(3)25(31)29-21-14-16(21)2/h5-9,12,16-17,20-21H,4,10-11,13-15H2,1-3H3,(H,27,28)(H,29,31)/t16?,17?,20-,21?/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	101	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM212822 (US9278954, 8.1) Show SMILES CCNC(=O)C(C)c1ccc(O[C@@H]2CCN(C2)c2ncc(CC3CCCC3)cc2F)cc1 Show InChI InChI=1S/C26H34FN3O2/c1-3-28-26(31)18(2)21-8-10-22(11-9-21)32-23-12-13-30(17-23)25-24(27)15-20(16-29-25)14-19-6-4-5-7-19/h8-11,15-16,18-19,23H,3-7,12-14,17H2,1-2H3,(H,28,31)/t18?,23-/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	104	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM101975 (US8530460, 1.55) Show SMILES C[C@H](NC(C)=O)c1ccc(OC2CN(C2)c2ccc(OC3CC3)cc2F)cc1 Show InChI InChI=1S/C22H25FN2O3/c1-14(24-15(2)26)16-3-5-17(6-4-16)28-20-12-25(13-20)22-10-9-19(11-21(22)23)27-18-7-8-18/h3-6,9-11,14,18,20H,7-8,12-13H2,1-2H3,(H,24,26)/t14-/m0/s1	PDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	110	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Enzyme assay using human acetyl-CoA carboxylase 2 (ACC).				US Patent US8530460 (2013) BindingDB Entry DOI: 10.7270/Q2X34W3N
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM212612 (US9278954, 1.3 | US9278954, 1.4) Show SMILES CCCNc1nccc(N2CC[C@H](C2)Oc2ccc(cc2)C(C)C(=O)NC2CC2C)c1F Show InChI InChI=1S/C25H33FN4O2/c1-4-11-27-24-23(26)22(9-12-28-24)30-13-10-20(15-30)32-19-7-5-18(6-8-19)17(3)25(31)29-21-14-16(21)2/h5-9,12,16-17,20-21H,4,10-11,13-15H2,1-3H3,(H,27,28)(H,29,31)/t16?,17?,20-,21?/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	118	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM101944 (US8530460, 1.24) Show SMILES C[C@H](NC(C)=O)c1ccc(OC2CN(C2)c2ccc3OCCOc3c2)cc1 Show InChI InChI=1S/C21H24N2O4/c1-14(22-15(2)24)16-3-6-18(7-4-16)27-19-12-23(13-19)17-5-8-20-21(11-17)26-10-9-25-20/h3-8,11,14,19H,9-10,12-13H2,1-2H3,(H,22,24)/t14-/m0/s1	PDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Enzyme assay using human acetyl-CoA carboxylase 2 (ACC).				US Patent US8530460 (2013) BindingDB Entry DOI: 10.7270/Q2X34W3N
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM97624 (US8470841, 59) Show SMILES CC(C)Oc1ccc(Oc2ccc(OC[C@H](C)NC(C)=O)cc2)cc1 Show InChI InChI=1S/C20H25NO4/c1-14(2)24-18-9-11-20(12-10-18)25-19-7-5-17(6-8-19)23-13-15(3)21-16(4)22/h5-12,14-15H,13H2,1-4H3,(H,21,22)/t15-/m0/s1	PDB MMDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	120	n/a	n/a	n/a	n/a	7.5	37
Sanofi US Patent					Assay Description the enzymatic activity of ACC and its inhibition by test substances were determined by a luminometric assay.				US Patent US8470841 (2013) BindingDB Entry DOI: 10.7270/Q2183537
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM212622 (BDBM212747 | US9278954, 1.13 | US9278954, 1.26) Show SMILES CC(C(=O)NC1CC1C)c1ccc(O[C@@H]2CCN(C2)c2ncnc(OCC(C)(C)O)c2Cl)cc1 Show InChI InChI=1S/C25H33ClN4O4/c1-15-11-20(15)29-23(31)16(2)17-5-7-18(8-6-17)34-19-9-10-30(12-19)22-21(26)24(28-14-27-22)33-13-25(3,4)32/h5-8,14-16,19-20,32H,9-13H2,1-4H3,(H,29,31)/t15?,16?,19-,20?/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	121	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM212636 (BDBM212752 | US9278954, 1.27) Show SMILES CCNC(=O)C(C)c1ccc(O[C@@H]2CCN(C2)c2nc(ncc2F)N(C)C)cc1 Show InChI InChI=1S/C21H28FN5O2/c1-5-23-20(28)14(2)15-6-8-16(9-7-15)29-17-10-11-27(13-17)19-18(22)12-24-21(25-19)26(3)4/h6-9,12,14,17H,5,10-11,13H2,1-4H3,(H,23,28)/t14?,17-/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	126	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM212622 (BDBM212747 | US9278954, 1.13 | US9278954, 1.26) Show SMILES CC(C(=O)NC1CC1C)c1ccc(O[C@@H]2CCN(C2)c2ncnc(OCC(C)(C)O)c2Cl)cc1 Show InChI InChI=1S/C25H33ClN4O4/c1-15-11-20(15)29-23(31)16(2)17-5-7-18(8-6-17)34-19-9-10-30(12-19)22-21(26)24(28-14-27-22)33-13-25(3,4)32/h5-8,14-16,19-20,32H,9-13H2,1-4H3,(H,29,31)/t15?,16?,19-,20?/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	127	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM101924 (US8530460, 1.4) Show SMILES CC(NC(C)=O)c1ccc(OC2CN(C2)c2ccc(OC3CCC3)cc2)cc1 Show InChI InChI=1S/C23H28N2O3/c1-16(24-17(2)26)18-6-10-21(11-7-18)28-23-14-25(15-23)19-8-12-22(13-9-19)27-20-4-3-5-20/h6-13,16,20,23H,3-5,14-15H2,1-2H3,(H,24,26)	PDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Enzyme assay using human acetyl-CoA carboxylase 2 (ACC).				US Patent US8530460 (2013) BindingDB Entry DOI: 10.7270/Q2X34W3N
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM101965 (US8530460, 1.45) Show SMILES C[C@H](NC(C)=O)c1ccc(OC2CN(C2)c2c(F)cc(OC3CC3)cc2F)cc1 Show InChI InChI=1S/C22H24F2N2O3/c1-13(25-14(2)27)15-3-5-16(6-4-15)29-19-11-26(12-19)22-20(23)9-18(10-21(22)24)28-17-7-8-17/h3-6,9-10,13,17,19H,7-8,11-12H2,1-2H3,(H,25,27)/t13-/m0/s1	PDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	130	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Enzyme assay using human acetyl-CoA carboxylase 2 (ACC).				US Patent US8530460 (2013) BindingDB Entry DOI: 10.7270/Q2X34W3N
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM212614 (US9278954, 1.5) Show SMILES CC(C(=O)NC1CC1)c1ccc(O[C@@H]2CCN(C2)c2ncnc(OCC(C)(F)F)c2F)cc1 Show InChI InChI=1S/C23H27F3N4O3/c1-14(21(31)29-16-5-6-16)15-3-7-17(8-4-15)33-18-9-10-30(11-18)20-19(24)22(28-13-27-20)32-12-23(2,25)26/h3-4,7-8,13-14,16,18H,5-6,9-12H2,1-2H3,(H,29,31)/t14?,18-/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	133	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM212645 (BDBM212750 | US9278954, 1.36) Show SMILES CC(C(=O)NCC(F)F)c1ccc(O[C@@H]2CCN(C2)c2ncnc(OCC(C)(C)O)c2Cl)cc1 Show InChI InChI=1S/C23H29ClF2N4O4/c1-14(21(31)27-10-18(25)26)15-4-6-16(7-5-15)34-17-8-9-30(11-17)20-19(24)22(29-13-28-20)33-12-23(2,3)32/h4-7,13-14,17-18,32H,8-12H2,1-3H3,(H,27,31)/t14?,17-/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	135	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM212610 (US9278954, 1.1 | US9278954, 6.1 isomer 1 | US92789...) Show SMILES CC(C(=O)NC1CC1)c1ccc(O[C@@H]2CCN(C2)c2ncnc(OCC(C)(C)O)c2Cl)cc1 Show InChI InChI=1S/C24H31ClN4O4/c1-15(22(30)28-17-6-7-17)16-4-8-18(9-5-16)33-19-10-11-29(12-19)21-20(25)23(27-14-26-21)32-13-24(2,3)31/h4-5,8-9,14-15,17,19,31H,6-7,10-13H2,1-3H3,(H,28,30)/t15?,19-/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	139	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM101938 (US8530460, 1.18) Show SMILES C[C@H](NC(C)=O)c1ccc(OC2CN(C2)c2ccc3OCC(C)(C)COc3c2)cc1 Show InChI InChI=1S/C24H30N2O4/c1-16(25-17(2)27)18-5-8-20(9-6-18)30-21-12-26(13-21)19-7-10-22-23(11-19)29-15-24(3,4)14-28-22/h5-11,16,21H,12-15H2,1-4H3,(H,25,27)/t16-/m0/s1	PDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Enzyme assay using human acetyl-CoA carboxylase 2 (ACC).				US Patent US8530460 (2013) BindingDB Entry DOI: 10.7270/Q2X34W3N
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM101993 (US8530460, 2.10) Show SMILES CCOc1ccc(cc1)N1CC(C1)Oc1ccc(cc1)[C@H](C)NC(=O)C1CC1 Show InChI InChI=1S/C23H28N2O3/c1-3-27-20-12-8-19(9-13-20)25-14-22(15-25)28-21-10-6-17(7-11-21)16(2)24-23(26)18-4-5-18/h6-13,16,18,22H,3-5,14-15H2,1-2H3,(H,24,26)/t16-/m0/s1	PDB B.MOAD GoogleScholar	PC cid PC sid UniChem Similars	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	n/a	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Enzyme assay using human acetyl-CoA carboxylase 2 (ACC).				US Patent US8530460 (2013) BindingDB Entry DOI: 10.7270/Q2X34W3N
					More data for this Ligand-Target Pair
Acetyl-CoA carboxylase 2 (ACC2) (Homo sapiens (Human))	BDBM212615 (BDBM212741 | US9278954, 1.6 | US9278954, 1.9) Show SMILES CC(C(=O)NC1CC1C)c1ccc(O[C@@H]2CCN(C2)c2nc(ncc2F)N(C)C)cc1 Show InChI InChI=1S/C23H30FN5O2/c1-14-11-20(14)26-22(30)15(2)16-5-7-17(8-6-16)31-18-9-10-29(13-18)21-19(24)12-25-23(27-21)28(3)4/h5-8,12,14-15,18,20H,9-11,13H2,1-4H3,(H,26,30)/t14?,15?,18-,20?/m1/s1	PDB GoogleScholar	PC cid PC sid UniChem	US Patent	n/a	n/a	140	n/a	n/a	n/a	n/a	7.5	n/a
Boehringer Ingelheim International GmbH US Patent					Assay Description Malonyl CoA formation by acetyl CoA carboxylases is stoichometrically linked to the consumption of ATP. ACC2 activity is measured in a NADH-linked ki...				US Patent US9278954 (2016) BindingDB Entry DOI: 10.7270/Q2RB73FM
					More data for this Ligand-Target Pair

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